[ { "uniprot_canonical_ac": "P40089-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 93, "chemical_mass": 10423.0, "gene_names": "LSM5;LSM5", "protein_name": "LSM complex subunit LSM5", "disease": [], "biological_process": [ { "name": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0000290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000290", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "sno(s)RNA-containing ribonucleoprotein complex", "id": "GO:0005732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005732", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "U6 snRNP", "id": "GO:0005688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005688", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" }, { "name": "Lsm1-7-Pat1 complex", "id": "GO:1990726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990726", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40089-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000948", "url": "https://www.yeastgenome.org/locus/S000000948" }, { "database": "iPTMnet", "id": "P40089", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40089" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40089-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Thr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000948", "url": "https://www.yeastgenome.org/locus/S000000948" }, { "database": "iPTMnet", "id": "P40089", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40089" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40089-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Slightly increases affinity for poly-URNA ends.", "evidence": [ { "database": "UniProtKB", "id": "P40089", "url": "https://www.uniprot.org/uniprotkb/P40089" }, { "database": "PubMed", "id": "24240276", "url": "https://glygen.org/publication/PubMed/24240276" }, { "database": "PubMed", "id": "24513854", "url": "https://glygen.org/publication/PubMed/24513854" } ] } ] } ], "record_id": "P40089-1" }, { "uniprot_canonical_ac": "P40090-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 624, "chemical_mass": 72141.0, "gene_names": "SCC4;SCC4", "protein_name": "MAU2 chromatid cohesion factor homolog", "disease": [], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" }, { "name": "mitotic chromosome condensation", "id": "GO:0007076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007076", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" }, { "name": "establishment of mitotic sister chromatid cohesion", "id": "GO:0034087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034087", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" }, { "name": "establishment of protein localization to chromatin", "id": "GO:0071169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071169", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" }, { "name": "rDNA chromatin condensation", "id": "GO:0070550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070550", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" } ], "cellular_component": [ { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" }, { "name": "SMC loading complex", "id": "GO:0032116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032116", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" } ], "molecular_function": [ { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" }, { "name": "kinetochore binding", "id": "GO:0043515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043515", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40090-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Ser387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000949", "url": "https://www.yeastgenome.org/locus/S000000949" }, { "database": "iPTMnet", "id": "P40090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40090" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40090-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Leu256", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "K", "comment": "In scc4m7; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with A-298; D-299; A-313; A-324; D-327; and D-331.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] } ] }, { "uniprot_canonical_ac": "P40090-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Tyr298", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "In scc4m7; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with K-256; D-299; A-313; A-324; D-327; and D-331.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] } ] }, { "uniprot_canonical_ac": "P40090-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Lys299", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "D", "comment": "In scc4m7; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with K-256; A-298; A-313; A-324; D-327; and D-331.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] } ] }, { "uniprot_canonical_ac": "P40090-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Tyr313", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "In scc4m7; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with K-256; A-298; D-299; A-324; D-327; and D-331.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] } ] }, { "uniprot_canonical_ac": "P40090-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Phe324", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "In scc4m35; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with A-327; A-331; A-540 and A-541. In scc4m7; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with K-256; A-298; D-299; A-313; D-327; and D-331.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] } ] }, { "uniprot_canonical_ac": "P40090-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Lys327", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In scc4m35; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with A-324; A-331; A-540 and A-541.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] }, { "sequence_org": "K", "sequence_mut": "D", "comment": "In scc4m7; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with K-256; A-298; D-299; A-313; A-324 and D-331.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] } ] }, { "uniprot_canonical_ac": "P40090-1", "start_pos": "331", "end_pos": "331", "site_lbl": "Lys331", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In scc4m35; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with A-324; A-327; A-540 and A-541.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] }, { "sequence_org": "K", "sequence_mut": "D", "comment": "In scc4m7; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with K-256; A-298; D-299; A-313; A-324 and D-327.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] } ] }, { "uniprot_canonical_ac": "P40090-1", "start_pos": "540", "end_pos": "540", "site_lbl": "Lys540", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In scc4m35; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with A-324; A-327; A-331 and A-541.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] } ] }, { "uniprot_canonical_ac": "P40090-1", "start_pos": "541", "end_pos": "541", "site_lbl": "Lys541", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In scc4m35; eliminates centromeric localization of SCC2 in mitotic cells and reduces association of the cohesin subunit SCC1 with the centromere and pericentromere; when associated with A-324; A-327; A-331 and A-540.", "evidence": [ { "database": "UniProtKB", "id": "P40090", "url": "https://www.uniprot.org/uniprotkb/P40090" }, { "database": "PubMed", "id": "26038942", "url": "https://glygen.org/publication/PubMed/26038942" } ] } ] } ], "record_id": "P40090-1" }, { "uniprot_canonical_ac": "P40094-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 801, "chemical_mass": 92544.0, "gene_names": "COG3;COG3;GRD20;SEC34", "protein_name": "Conserved oligomeric Golgi complex subunit 3", "disease": [ { "disease_id": "DOID:0051047", "name": "congenital disorder of glycosylation type IIbb", "description": "A congenital disorder of glycosylation type II that is characterized by global developmental delay, severely impaired intellectual development, microcephaly, epilepsy, facial dysmorphism, and variable neurologic findings and that has_material_basis_in homozygous mutation in the COG3 gene on chromosome 13q14.", "url": "https://disease-ontology.org/term/DOID:0051047", "evidence": [ { "id": "0051047", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051047" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" } ], "biological_process": [ { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" }, { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" } ], "molecular_function": [ { "name": "cargo adaptor activity", "id": "GO:0140312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140312", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40094-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Thr264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Ser469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Thr471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Ser472", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Ser507", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Ser515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Ser518", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "521", "end_pos": "521", "site_lbl": "Ser521", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Thr522", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "645", "end_pos": "645", "site_lbl": "Ser645", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Ser647", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40094", "url": "https://www.uniprot.org/uniprotkb/P40094" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "798", "end_pos": "798", "site_lbl": "Thr798", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "800", "end_pos": "800", "site_lbl": "Thr800", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40094-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000959", "url": "https://www.yeastgenome.org/locus/S000000959" }, { "database": "iPTMnet", "id": "P40094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40094" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40094-1" }, { "uniprot_canonical_ac": "P40096-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 142, "chemical_mass": 15517.0, "gene_names": "BUR6;BUR6;NCB1", "protein_name": "Negative cofactor 2 complex subunit alpha", "disease": [], "biological_process": [ { "name": "negative regulation of RNA polymerase II transcription preinitiation complex assembly", "id": "GO:0017055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017055", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" }, { "name": "negative cofactor 2 complex", "id": "GO:0017054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017054", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40096-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Thr135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40096" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000961", "url": "https://www.yeastgenome.org/locus/S000000961" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40096-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40096" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000961", "url": "https://www.yeastgenome.org/locus/S000000961" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40096-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40096", "url": "https://www.uniprot.org/uniprotkb/P40096" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40096" }, { "database": "SGD", "id": "S000000961", "url": "https://www.yeastgenome.org/locus/S000000961" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40096-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Thr64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P15790-1", "kinase_gene_name": "CKA1", "evidence": [ { "database": "iPTMnet", "id": "P40096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40096" }, { "database": "PubMed", "id": "12502746", "url": "https://glygen.org/publication/PubMed/12502746" } ] }, { "kinase_uniprot_canonical_ac": "P19454-1", "kinase_gene_name": "CKA2", "evidence": [ { "database": "iPTMnet", "id": "P40096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40096" }, { "database": "PubMed", "id": "12502746", "url": "https://glygen.org/publication/PubMed/12502746" } ] }, { "kinase_uniprot_canonical_ac": "P38930-1", "kinase_gene_name": "CKB2", "evidence": [ { "database": "iPTMnet", "id": "P40096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40096" }, { "database": "PubMed", "id": "12502746", "url": "https://glygen.org/publication/PubMed/12502746" } ] }, { "kinase_uniprot_canonical_ac": "P43639-1", "kinase_gene_name": "CKB1", "evidence": [ { "database": "iPTMnet", "id": "P40096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40096" }, { "database": "PubMed", "id": "12502746", "url": "https://glygen.org/publication/PubMed/12502746" } ] } ] }, { "uniprot_canonical_ac": "P40096-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40096" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40096-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000961", "url": "https://www.yeastgenome.org/locus/S000000961" }, { "database": "iPTMnet", "id": "P40096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40096" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P40096-1" }, { "uniprot_canonical_ac": "P40416-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 690, "chemical_mass": 77522.0, "gene_names": "ATM1;ATM1;MDY;YM9952.03C", "protein_name": "Iron-sulfur clusters transporter ATM1, mitochondrial", "disease": [ { "disease_id": "DOID:0050554", "name": "X-linked sideroblastic anemia with ataxia", "description": "A sideroblastic anemia that is characterized by decreased production of hemoglobin and ataxia and has_material_basis_in the mutation in the ABCB7 gene.", "url": "https://disease-ontology.org/term/DOID:0050554", "evidence": [ { "id": "0050554", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050554" } ], "weight": 0.0 }, { "disease_id": "DOID:8955", "name": "sideroblastic anemia", "description": "A microcytic anemia where the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes).", "url": "https://disease-ontology.org/term/DOID:8955", "evidence": [ { "id": "8955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8955" } ], "weight": 0.0 } ], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" }, { "name": "mitochondrial transmembrane transport", "id": "GO:1990542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990542", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" }, { "name": "iron-sulfur cluster export from the mitochondrion", "id": "GO:0140466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140466", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" }, { "name": "iron-sulfur cluster transmembrane transport", "id": "GO:1902497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902497", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40416-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40416", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40416" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004916", "url": "https://www.yeastgenome.org/locus/S000004916" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40416-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Arg216", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Decreases ATP hydrolysis. Decreases transporter activity.", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" }, { "database": "PubMed", "id": "25006243", "url": "https://glygen.org/publication/PubMed/25006243" } ] } ] }, { "uniprot_canonical_ac": "P40416-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Lys475", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "M", "comment": "Loss of function; significant decrease in ATP-binding; no homodimerization.", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" }, { "database": "PubMed", "id": "15225610", "url": "https://glygen.org/publication/PubMed/15225610" } ] }, { "sequence_org": "K", "sequence_mut": "", "comment": "Decreases ATP hydrolysis. Decreases transporter activity.", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" }, { "database": "PubMed", "id": "25006243", "url": "https://glygen.org/publication/PubMed/25006243" } ] } ] }, { "uniprot_canonical_ac": "P40416-1", "start_pos": "598", "end_pos": "598", "site_lbl": "Glu598", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Loss of function; slight decrease in ATP-binding.", "evidence": [ { "database": "UniProtKB", "id": "P40416", "url": "https://www.uniprot.org/uniprotkb/P40416" }, { "database": "PubMed", "id": "15225610", "url": "https://glygen.org/publication/PubMed/15225610" } ] } ] } ], "record_id": "P40416-1" }, { "uniprot_canonical_ac": "P49166-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49166", "url": "https://www.uniprot.org/uniprotkb/P49166" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 88, "chemical_mass": 9850.0, "gene_names": "RPL37A;L9470.6;RPL35A;RPL37A", "protein_name": "Large ribosomal subunit protein eL37A", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P49166", "url": "https://www.uniprot.org/uniprotkb/P49166" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P49166", "url": "https://www.uniprot.org/uniprotkb/P49166" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "P49166", "url": "https://www.uniprot.org/uniprotkb/P49166" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P49166", "url": "https://www.uniprot.org/uniprotkb/P49166" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P49166", "url": "https://www.uniprot.org/uniprotkb/P49166" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P49166", "url": "https://www.uniprot.org/uniprotkb/P49166" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P49166", "url": "https://www.uniprot.org/uniprotkb/P49166" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P49166", "url": "https://www.uniprot.org/uniprotkb/P49166" } ], "pmid": "" }, { "name": "cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000448", "evidence": [ { "database": "UniProtKB", "id": "P49166", "url": "https://www.uniprot.org/uniprotkb/P49166" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49166-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Thr17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Thr44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Tyr47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Thr80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49166-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004175", "url": "https://www.yeastgenome.org/locus/S000004175" }, { "database": "iPTMnet", "id": "P49166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49166" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P49166-1" }, { "uniprot_canonical_ac": "P52553-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 114, "chemical_mass": 13284.0, "gene_names": "YKE2;GIM1;L8167.8;PFD6;YKE2", "protein_name": "Prefoldin subunit 6", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "pmid": "" }, { "name": "prefoldin complex", "id": "GO:0016272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016272", "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "pmid": "" }, { "name": "tubulin complex assembly", "id": "GO:0007021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007021", "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "pmid": "" }, { "name": "chaperone-mediated protein complex assembly", "id": "GO:0051131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051131", "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P52553", "url": "https://www.uniprot.org/uniprotkb/P52553" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P52553-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Thr106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52553", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52553" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P52553-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004190", "url": "https://www.yeastgenome.org/locus/S000004190" }, { "database": "iPTMnet", "id": "P52553", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52553" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52553-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Thr110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004190", "url": "https://www.yeastgenome.org/locus/S000004190" }, { "database": "iPTMnet", "id": "P52553", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52553" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P52553-1" }, { "uniprot_canonical_ac": "P53137-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53137", "url": "https://www.uniprot.org/uniprotkb/P53137" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 624, "chemical_mass": 72043.0, "gene_names": "CUE3;CUE3;G3060;RQT3", "protein_name": "RQC trigger complex subunit CUE3", "disease": [], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "P53137", "url": "https://www.uniprot.org/uniprotkb/P53137" } ], "pmid": "" }, { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "P53137", "url": "https://www.uniprot.org/uniprotkb/P53137" } ], "pmid": "" }, { "name": "ribosome-associated ubiquitin-dependent protein catabolic process", "id": "GO:1990116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990116", "evidence": [ { "database": "UniProtKB", "id": "P53137", "url": "https://www.uniprot.org/uniprotkb/P53137" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53137", "url": "https://www.uniprot.org/uniprotkb/P53137" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "P53137", "url": "https://www.uniprot.org/uniprotkb/P53137" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "P53137", "url": "https://www.uniprot.org/uniprotkb/P53137" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "P53137", "url": "https://www.uniprot.org/uniprotkb/P53137" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53137-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Ser288", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53137", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53137" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003078", "url": "https://www.yeastgenome.org/locus/S000003078" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53137-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53137", "url": "https://www.uniprot.org/uniprotkb/P53137" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53137", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53137" }, { "database": "SGD", "id": "S000003078", "url": "https://www.yeastgenome.org/locus/S000003078" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53137-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Ser383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003078", "url": "https://www.yeastgenome.org/locus/S000003078" }, { "database": "iPTMnet", "id": "P53137", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53137" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53137-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Thr385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003078", "url": "https://www.yeastgenome.org/locus/S000003078" }, { "database": "iPTMnet", "id": "P53137", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53137" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53137-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Ser461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003078", "url": "https://www.yeastgenome.org/locus/S000003078" }, { "database": "iPTMnet", "id": "P53137", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53137" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53137-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Ser529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003078", "url": "https://www.yeastgenome.org/locus/S000003078" }, { "database": "iPTMnet", "id": "P53137", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53137" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53137-1" }, { "uniprot_canonical_ac": "P53251-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53251", "url": "https://www.uniprot.org/uniprotkb/P53251" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 210, "chemical_mass": 24069.0, "gene_names": "SLX9;SLX9", "protein_name": "Ribosome biogenesis protein SLX9", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53251", "url": "https://www.uniprot.org/uniprotkb/P53251" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P53251", "url": "https://www.uniprot.org/uniprotkb/P53251" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "P53251", "url": "https://www.uniprot.org/uniprotkb/P53251" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P53251", "url": "https://www.uniprot.org/uniprotkb/P53251" } ], "pmid": "" } ], "molecular_function": [ { "name": "G-quadruplex DNA binding", "id": "GO:0051880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051880", "evidence": [ { "database": "UniProtKB", "id": "P53251", "url": "https://www.uniprot.org/uniprotkb/P53251" } ], "pmid": "" } ], "biological_process": [ { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "P53251", "url": "https://www.uniprot.org/uniprotkb/P53251" } ], "pmid": "" }, { "name": "ribosomal small subunit export from nucleus", "id": "GO:0000056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000056", "evidence": [ { "database": "UniProtKB", "id": "P53251", "url": "https://www.uniprot.org/uniprotkb/P53251" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53251-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003313", "url": "https://www.yeastgenome.org/locus/S000003313" }, { "database": "iPTMnet", "id": "P53251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53251" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53251-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Thr72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53251" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] } ], "record_id": "P53251-1" }, { "uniprot_canonical_ac": "P53759-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53759", "url": "https://www.uniprot.org/uniprotkb/P53759" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 423, "chemical_mass": 48131.0, "gene_names": "DUS1;DUS1", "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53759", "url": "https://www.uniprot.org/uniprotkb/P53759" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "P53759", "url": "https://www.uniprot.org/uniprotkb/P53759" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "P53759", "url": "https://www.uniprot.org/uniprotkb/P53759" } ], "pmid": "" } ], "molecular_function": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "P53759", "url": "https://www.uniprot.org/uniprotkb/P53759" } ], "pmid": "" }, { "name": "tRNA dihydrouridine synthase activity", "id": "GO:0017150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017150", "evidence": [ { "database": "UniProtKB", "id": "P53759", "url": "https://www.uniprot.org/uniprotkb/P53759" } ], "pmid": "" }, { "name": "mRNA dihydrouridine synthase activity", "id": "GO:0106414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106414", "evidence": [ { "database": "UniProtKB", "id": "P53759", "url": "https://www.uniprot.org/uniprotkb/P53759" } ], "pmid": "" }, { "name": "tRNA-dihydrouridine16 synthase activity", "id": "GO:0102262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102262", "evidence": [ { "database": "UniProtKB", "id": "P53759", "url": "https://www.uniprot.org/uniprotkb/P53759" } ], "pmid": "" }, { "name": "tRNA-dihydrouridine17 synthase activity", "id": "GO:0102263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102263", "evidence": [ { "database": "UniProtKB", "id": "P53759", "url": "https://www.uniprot.org/uniprotkb/P53759" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53759-1" }, { "uniprot_canonical_ac": "Q06217-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 110, "chemical_mass": 12853.0, "gene_names": "SMD2;L9328.5;SMD2", "protein_name": "Small nuclear ribonucleoprotein Sm D2", "disease": [ { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "pICln-Sm protein complex", "id": "GO:0034715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034715", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "Prp19 complex", "id": "GO:0000974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000974", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" } ], "biological_process": [ { "name": "7-methylguanosine cap hypermethylation", "id": "GO:0036261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036261", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q06217", "url": "https://www.uniprot.org/uniprotkb/Q06217" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06217-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004265", "url": "https://www.yeastgenome.org/locus/S000004265" }, { "database": "iPTMnet", "id": "Q06217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06217" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06217-1" }, { "uniprot_canonical_ac": "Q06696-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 566, "chemical_mass": 64018.0, "gene_names": "VPS36;GRD12;VAC3;VPL11;VPS36", "protein_name": "Vacuolar protein-sorting-associated protein 36", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ESCRT II complex", "id": "GO:0000814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000814", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043328", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" }, { "name": "protein retention in Golgi apparatus", "id": "GO:0045053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045053", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "Q06696", "url": "https://www.uniprot.org/uniprotkb/Q06696" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06696-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Ser232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004409", "url": "https://www.yeastgenome.org/locus/S000004409" }, { "database": "iPTMnet", "id": "Q06696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06696" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06696-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Ser305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004409", "url": "https://www.yeastgenome.org/locus/S000004409" }, { "database": "iPTMnet", "id": "Q06696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06696" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06696-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Ser327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004409", "url": "https://www.yeastgenome.org/locus/S000004409" }, { "database": "iPTMnet", "id": "Q06696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06696" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06696-1" }, { "uniprot_canonical_ac": "P31412-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 392, "chemical_mass": 44189.0, "gene_names": "VMA5;CSL5;VAT3;VATC;VMA5;YKL410", "protein_name": "V-type proton ATPase subunit C", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:5517", "name": "stomach carcinoma", "description": "A stomach cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:5517", "evidence": [ { "id": "5517", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5517" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V1 domain", "id": "GO:0000221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000221", "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" } ], "pmid": "" }, { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" } ], "pmid": "" } ], "biological_process": [ { "name": "endosomal lumen acidification", "id": "GO:0048388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048388", "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" } ], "pmid": "" }, { "name": "Golgi lumen acidification", "id": "GO:0061795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061795", "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31412-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Thr167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31412" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P31412-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001563", "url": "https://www.yeastgenome.org/locus/S000001563" }, { "database": "iPTMnet", "id": "P31412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31412" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31412-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001563", "url": "https://www.yeastgenome.org/locus/S000001563" }, { "database": "iPTMnet", "id": "P31412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31412" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31412-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Ser209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001563", "url": "https://www.yeastgenome.org/locus/S000001563" }, { "database": "iPTMnet", "id": "P31412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31412" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31412-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001563", "url": "https://www.yeastgenome.org/locus/S000001563" }, { "database": "iPTMnet", "id": "P31412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31412" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31412-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Ser338", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31412" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P31412-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Thr37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001563", "url": "https://www.yeastgenome.org/locus/S000001563" }, { "database": "iPTMnet", "id": "P31412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31412" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31412-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001563", "url": "https://www.yeastgenome.org/locus/S000001563" }, { "database": "iPTMnet", "id": "P31412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31412" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31412-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Thr60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001563", "url": "https://www.yeastgenome.org/locus/S000001563" }, { "database": "iPTMnet", "id": "P31412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31412" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31412-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001563", "url": "https://www.yeastgenome.org/locus/S000001563" }, { "database": "iPTMnet", "id": "P31412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31412" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31412-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Phe255", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Is rapidly degraded and disrupts stable ATPase assembly.", "evidence": [ { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412" }, { "database": "PubMed", "id": "11777935", "url": "https://glygen.org/publication/PubMed/11777935" } ] } ] } ], "record_id": "P31412-1" }, { "uniprot_canonical_ac": "P32074-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 935, "chemical_mass": 104831.0, "gene_names": "SEC21;N0543;SEC21", "protein_name": "Coatomer subunit gamma", "disease": [ { "disease_id": "DOID:0061093", "name": "immunodeficiency 128", "description": "A T cell, B cell, and NK cell deficiency that is characterized by the onset of recurrent bacterial and viral infections in the first year of life and that has_material_basis_in homozygous mutation in the COPG1 gene on chromosome 3q21.", "url": "https://disease-ontology.org/term/DOID:0061093", "evidence": [ { "id": "0061093", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061093" } ], "weight": 0.0 }, { "disease_id": "DOID:0111962", "name": "combined immunodeficiency", "description": "A primary immunodeficiency disease that involves multiple components of the immune system.", "url": "https://disease-ontology.org/term/DOID:0111962", "evidence": [ { "id": "0111962", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111962" } ], "weight": 0.0 }, { "disease_id": "DOID:2344", "name": "polyclonal hypergammaglobulinemia", "description": "", "url": "https://disease-ontology.org/term/DOID:2344", "evidence": [ { "id": "2344", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2344" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" }, { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32074-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Thr175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Ser278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Thr283", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Ser504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "581", "end_pos": "581", "site_lbl": "Ser581", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "584", "end_pos": "584", "site_lbl": "Ser584", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Thr610", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "631", "end_pos": "631", "site_lbl": "Ser631", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "633", "end_pos": "633", "site_lbl": "Thr633", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "634", "end_pos": "634", "site_lbl": "Thr634", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "637", "end_pos": "637", "site_lbl": "Thr637", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "638", "end_pos": "638", "site_lbl": "Thr638", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "643", "end_pos": "643", "site_lbl": "Ser643", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "653", "end_pos": "653", "site_lbl": "Ser653", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32074", "url": "https://www.uniprot.org/uniprotkb/P32074" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "695", "end_pos": "695", "site_lbl": "Ser695", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32074-1", "start_pos": "873", "end_pos": "873", "site_lbl": "Ser873", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005231", "url": "https://www.yeastgenome.org/locus/S000005231" }, { "database": "iPTMnet", "id": "P32074", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32074" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32074-1" }, { "uniprot_canonical_ac": "P32461-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 534, "chemical_mass": 59775.0, "gene_names": "DPH2;DPH2", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "disease": [ { "disease_id": "DOID:0070476", "name": "diphthamide deficiency syndrome", "description": "An inherited metabolic disorder characterized by global developmental delay, short stature, dysmorphic craniofacial features, and sparse hair that has_material_basis_in deficient diphthamidylation of the eukaryotic translation Elongation Factor 2 protein (gene: EEF2).", "url": "https://disease-ontology.org/term/DOID:0070476", "evidence": [ { "id": "0070476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070476" } ], "weight": 0.0 }, { "disease_id": "DOID:0070478", "name": "diphthamide deficiency syndrome 2", "description": "A diphthamide deficiency syndrome that has_material_basis_in homozygous or compound heterozygous mutations in the DPH2 gene on chromosome 1p34.1.", "url": "https://disease-ontology.org/term/DOID:0070478", "evidence": [ { "id": "0070478", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070478" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" } ], "pmid": "" }, { "name": "2-(3-amino-3-carboxypropyl)histidine synthase complex", "id": "GO:0120513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120513", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" } ], "pmid": "" }, { "name": "2-(3-amino-3-carboxypropyl)histidine synthase activity", "id": "GO:0090560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090560", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" } ], "pmid": "" } ], "biological_process": [ { "name": "protein histidyl modification to diphthamide", "id": "GO:0017183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017183", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32461-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Thr21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001674", "url": "https://www.yeastgenome.org/locus/S000001674" }, { "database": "iPTMnet", "id": "P32461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32461" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "440", "end_pos": "440", "site_lbl": "Ser440", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001674", "url": "https://www.yeastgenome.org/locus/S000001674" }, { "database": "iPTMnet", "id": "P32461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32461" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "449", "end_pos": "449", "site_lbl": "Thr449", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001674", "url": "https://www.yeastgenome.org/locus/S000001674" }, { "database": "iPTMnet", "id": "P32461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32461" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Thr469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001674", "url": "https://www.yeastgenome.org/locus/S000001674" }, { "database": "iPTMnet", "id": "P32461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32461" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Ser471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001674", "url": "https://www.yeastgenome.org/locus/S000001674" }, { "database": "iPTMnet", "id": "P32461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32461" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "478", "end_pos": "478", "site_lbl": "Thr478", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001674", "url": "https://www.yeastgenome.org/locus/S000001674" }, { "database": "iPTMnet", "id": "P32461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32461" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "482", "end_pos": "482", "site_lbl": "Ser482", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001674", "url": "https://www.yeastgenome.org/locus/S000001674" }, { "database": "iPTMnet", "id": "P32461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32461" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ser484", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001674", "url": "https://www.yeastgenome.org/locus/S000001674" }, { "database": "iPTMnet", "id": "P32461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32461" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "496", "end_pos": "496", "site_lbl": "Ser496", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32461" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001674", "url": "https://www.yeastgenome.org/locus/S000001674" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Thr506", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001674", "url": "https://www.yeastgenome.org/locus/S000001674" }, { "database": "iPTMnet", "id": "P32461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32461" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Cys106", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Normal sensitivity to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Cys107", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Resistance to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Normal sensitivity to diphtheria toxin. Abolishes [4Fe-4S] cluster binding and leads to abnormal reduction of the DPH1 [4Fe-4S] cluster; when associated with S-362.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Cys128", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Resistance to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Normal sensitivity to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Cys167", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Normal sensitivity to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Lys239", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "C", "comment": "Abolishes diphthamide modification of elongation factor 2. Resistance to diphtheria toxin and sordarin. Sensitive to hygromycin B.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "32576952", "url": "https://glygen.org/publication/PubMed/32576952" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Cys304", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Normal sensitivity to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Cys33", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Normal sensitivity to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Cys358", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Normal sensitivity to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] }, { "uniprot_canonical_ac": "P32461-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Cys362", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Resistance to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Resistance to diphtheria toxin. Abolishes [4Fe-4S] cluster binding and leads to abnormal reduction of the DPH1 [4Fe-4S] cluster; when associated with S-107.", "evidence": [ { "database": "UniProtKB", "id": "P32461", "url": "https://www.uniprot.org/uniprotkb/P32461" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] } ], "record_id": "P32461-1" }, { "uniprot_canonical_ac": "P32563-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 840, "chemical_mass": 95529.0, "gene_names": "VPH1;VPH1", "protein_name": "V-type proton ATPase subunit a, vacuolar isoform", "disease": [ { "disease_id": "DOID:0061166", "name": "autosomal recessive distal renal tubular acidosis 3 with or without sensorineural hearing loss", "description": "A renal tubular transport disease characterized by the failure of the kidney to produce an appropriately acid urine in the presence of systemic metabolic acidosis or after acid loading, due to failure of hydrogen ion secretion or bicarbonate reabsorption in the distal nephron that has_material_basis_in homozygous mutation in the ATP6N1B gene on chromosome 7q34.", "url": "https://disease-ontology.org/term/DOID:0061166", "evidence": [ { "id": "0061166", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061166" } ], "weight": 0.0 }, { "disease_id": "DOID:0070134", "name": "autosomal recessive cutis laxa type IIA", "description": "An autosomal recessive cutis laxa type II classic type that has_material_basis_in homozygous or compound heterozygous mutations in the ATP6V0A2 gene on chromosome 12q24.", "url": "https://disease-ontology.org/term/DOID:0070134", "evidence": [ { "id": "0070134", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070134" } ], "weight": 0.0 }, { "disease_id": "DOID:0070390", "name": "developmental and epileptic encephalopathy 104", "description": "A developmental and epileptic encephalopathy characterized by developmental delay in the first few months of life and drug-resistant focal and generalized tonic-clonic seizures that has_material_basis_in heterozygous mutation in the ATP6V0A1 on chromosome 17q21.", "url": "https://disease-ontology.org/term/DOID:0070390", "evidence": [ { "id": "0070390", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070390" } ], "weight": 0.0 }, { "disease_id": "DOID:0110942", "name": "autosomal recessive osteopetrosis 1", "description": "An osteopetrosis characterized by autosomal recessive inheritance that has_material_basis_in homozygous or compound heterozygous mutation in the TCIRG1 gene on chromosome 11q13.2.", "url": "https://disease-ontology.org/term/DOID:0110942", "evidence": [ { "id": "0110942", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110942" } ], "weight": 0.0 }, { "disease_id": "DOID:0112171", "name": "wrinkly skin syndrome", "description": "A syndrome characterized by sagging or wrinkly skin, reduced skin elasticity, delayed closure of the fontanel, typically mild developmental delay, and variable other skeletal, neurological and facial features that has_material_basis_in homozygous or compound heterozygous mutation in the ATP6V0A2 gene on chromosome 12q24.31.", "url": "https://disease-ontology.org/term/DOID:0112171", "evidence": [ { "id": "0112171", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112171" } ], "weight": 0.0 }, { "disease_id": "DOID:11836", "name": "clubfoot", "description": "A bone development disease where one or both are inclined inwards, axially rotated outwards, and pointing downwards with concomitant soft tissue abnormalities.", "url": "https://disease-ontology.org/term/DOID:11836", "evidence": [ { "id": "11836", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11836" } ], "weight": 0.0 }, { "disease_id": "DOID:14219", "name": "renal tubular acidosis", "description": "A renal tubular transport disease characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic acidosis.", "url": "https://disease-ontology.org/term/DOID:14219", "evidence": [ { "id": "14219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14219" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cellular response to alkaline pH", "id": "GO:0071469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071469", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "cellular hyperosmotic response", "id": "GO:0071474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071474", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "protein localization to vacuolar membrane", "id": "GO:1903778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903778", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "polyphosphate metabolic process", "id": "GO:0006797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006797", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase complex", "id": "GO:0016471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016471", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V0 domain", "id": "GO:0000220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000220", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" }, { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32563-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005796", "url": "https://www.yeastgenome.org/locus/S000005796" }, { "database": "iPTMnet", "id": "P32563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32563" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Ser162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005796", "url": "https://www.yeastgenome.org/locus/S000005796" }, { "database": "iPTMnet", "id": "P32563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32563" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "671", "end_pos": "671", "site_lbl": "Thr671", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005796", "url": "https://www.yeastgenome.org/locus/S000005796" }, { "database": "iPTMnet", "id": "P32563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32563" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "676", "end_pos": "676", "site_lbl": "Ser676", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32563" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005796", "url": "https://www.yeastgenome.org/locus/S000005796" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "677", "end_pos": "677", "site_lbl": "Ser677", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32563" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005796", "url": "https://www.yeastgenome.org/locus/S000005796" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "687", "end_pos": "687", "site_lbl": "Ser687", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005796", "url": "https://www.yeastgenome.org/locus/S000005796" }, { "database": "iPTMnet", "id": "P32563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32563" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "425", "end_pos": "425", "site_lbl": "Asp425", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Reduces assembly of V-ATPase complexes and reduces ATPase activity of the assembled complexes.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Lys538", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Reduces assembly of V-ATPase complexes.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "593", "end_pos": "593", "site_lbl": "Lys593", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Reduces ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "634", "end_pos": "634", "site_lbl": "Gln634", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "L", "comment": "Reduces subunit stability.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "729", "end_pos": "729", "site_lbl": "His729", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "R", "comment": "Reduces ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "735", "end_pos": "735", "site_lbl": "Arg735", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "L", "comment": "Reduces subunit stability.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "739", "end_pos": "739", "site_lbl": "Leu739", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "Reduces ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "743", "end_pos": "743", "site_lbl": "His743", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Reduces ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] }, { "sequence_org": "H", "sequence_mut": "E", "comment": "Reduces ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] }, { "sequence_org": "H", "sequence_mut": "Y", "comment": "Reduces ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "746", "end_pos": "746", "site_lbl": "Leu746", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "Reduces ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "780", "end_pos": "780", "site_lbl": "Leu780", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "Reduces assembly of V-ATPase complexes.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "789", "end_pos": "789", "site_lbl": "Glu789", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Abolishes ATPase activity and proton transport, but does not affect complex assembly.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] }, { "sequence_org": "E", "sequence_mut": "D", "comment": "Abolishes ATPase activity and proton transport, but does not affect complex assembly.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] }, { "sequence_org": "E", "sequence_mut": "H", "comment": "Abolishes ATPase activity and proton transport, but does not affect complex assembly.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] }, { "sequence_org": "E", "sequence_mut": "Q", "comment": "Abolishes ATPase activity and proton transport, but does not affect complex assembly.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" }, { "database": "PubMed", "id": "8798414", "url": "https://glygen.org/publication/PubMed/8798414" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "800", "end_pos": "800", "site_lbl": "Leu800", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "Reduces assembly of V-ATPase complexes.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "802", "end_pos": "802", "site_lbl": "Trp802", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "R", "comment": "Reduces assembly of V-ATPase complexes.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "803", "end_pos": "803", "site_lbl": "Val803", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "D", "comment": "Reduces ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" } ] }, { "sequence_org": "V", "sequence_mut": "F", "comment": "Reduces assembly of V-ATPase complexes.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "809", "end_pos": "809", "site_lbl": "Phe809", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "L", "comment": "Reduces assembly of V-ATPase complexes.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" } ] } ] }, { "uniprot_canonical_ac": "P32563-1", "start_pos": "814", "end_pos": "814", "site_lbl": "Gly814", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Reduces assembly of V-ATPase complexes.", "evidence": [ { "database": "UniProtKB", "id": "P32563", "url": "https://www.uniprot.org/uniprotkb/P32563" }, { "database": "PubMed", "id": "9506970", "url": "https://glygen.org/publication/PubMed/9506970" } ] } ] } ], "record_id": "P32563-1" }, { "uniprot_canonical_ac": "P32800-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 271, "chemical_mass": 30752.0, "gene_names": "PEX2;CRT1;HRA271;J0240;PAS5;PEX2", "protein_name": "Peroxisomal biogenesis factor 2", "disease": [ { "disease_id": "DOID:0080480", "name": "peroxisome biogenesis disorder 5A", "description": "A Zellweger syndrome that has_material_basis_in homozygous mutation in the PEX2 gene on chromosome 8q21.", "url": "https://disease-ontology.org/term/DOID:0080480", "evidence": [ { "id": "0080480", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080480" } ], "weight": 0.0 }, { "disease_id": "DOID:0081434", "name": "Peroxisome biogenesis disorder 5B", "description": "A peroxisomal biogenesis disorder that is characterized by the overlapping phenotypes of neonatal adrenoleukodystrophy and infantile Refsum disease and that has_material_basis_in homozygous or compound heterozygous mutation in the PEX2 gene on chromosome 8q21.", "url": "https://disease-ontology.org/term/DOID:0081434", "evidence": [ { "id": "0081434", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081434" } ], "weight": 0.0 }, { "disease_id": "DOID:905", "name": "Zellweger syndrome", "description": "A peroxisomal biogenesis disorder that is characterized by severe neurologic dysfunction, craniofacial abnormalities, and liver dysfunction, and biochemically by the absence of peroxisome and that has_material_basis_in autosomal recessive inheritance of a mutation in the peroxisome biogenesis factor (PEX) genes.", "url": "https://disease-ontology.org/term/DOID:905", "evidence": [ { "id": "905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:905" } ], "weight": 0.0 }, { "disease_id": "DOID:906", "name": "peroxisomal disease", "description": "An inherited metabolic disorder that involves peroxisome malfunction.", "url": "https://disease-ontology.org/term/DOID:906", "evidence": [ { "id": "906", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:906" } ], "weight": 0.0 } ], "biological_process": [ { "name": "protein import into peroxisome matrix, substrate release", "id": "GO:0044721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044721", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix", "id": "GO:0016558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016558", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix, receptor recycling", "id": "GO:0016562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016562", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" } ], "cellular_component": [ { "name": "peroxisomal importomer complex", "id": "GO:1990429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990429", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" }, { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" }, { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32800-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003746", "url": "https://www.yeastgenome.org/locus/S000003746" }, { "database": "iPTMnet", "id": "P32800", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32800" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32800-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32800", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32800" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003746", "url": "https://www.yeastgenome.org/locus/S000003746" } ] } ] }, { "uniprot_canonical_ac": "P32800-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Cys237", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolished protein import in peroxisomes.", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" }, { "database": "PubMed", "id": "35768507", "url": "https://glygen.org/publication/PubMed/35768507" } ] } ] }, { "uniprot_canonical_ac": "P32800-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Asp257", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Does not affect assembly of the PEX2-PEX10-PEX12 complex.", "evidence": [ { "database": "UniProtKB", "id": "P32800", "url": "https://www.uniprot.org/uniprotkb/P32800" }, { "database": "PubMed", "id": "35768507", "url": "https://glygen.org/publication/PubMed/35768507" } ] } ] } ], "record_id": "P32800-1" }, { "uniprot_canonical_ac": "P32916-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 621, "chemical_mass": 69278.0, "gene_names": "SRP101;D9819.3;SRP101", "protein_name": "Signal recognition particle receptor subunit alpha homolog", "disease": [], "cellular_component": [ { "name": "signal recognition particle receptor complex", "id": "GO:0005785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005785", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" } ], "pmid": "" } ], "molecular_function": [ { "name": "signal recognition particle binding", "id": "GO:0005047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005047", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition", "id": "GO:0006617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006617", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32916-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" }, { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32916-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" }, { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32916-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Ser232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" }, { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32916-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" }, { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32916-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32916-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Ser238", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" } ] } ] }, { "uniprot_canonical_ac": "P32916-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32916-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Thr246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" }, { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32916-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Ser271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" }, { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32916-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Ser272", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" }, { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32916-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Ser523", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32916", "url": "https://www.uniprot.org/uniprotkb/P32916" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32916", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32916" }, { "database": "SGD", "id": "S000002700", "url": "https://www.yeastgenome.org/locus/S000002700" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32916-1" }, { "uniprot_canonical_ac": "P33309-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 386, "chemical_mass": 44058.0, "gene_names": "DOM34;DOM34;N2016", "protein_name": "Protein DOM34", "disease": [], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, non-stop decay", "id": "GO:0070481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070481", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "nonfunctional rRNA decay", "id": "GO:0070651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070651", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "RNA surveillance", "id": "GO:0071025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071025", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, no-go decay", "id": "GO:0070966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070966", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "Dom34-Hbs1 complex", "id": "GO:1990533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990533", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33309-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Pro216", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "Reduced No-Go Decay (NGD) pathway.", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" }, { "database": "PubMed", "id": "19420139", "url": "https://glygen.org/publication/PubMed/19420139" } ] } ] }, { "uniprot_canonical_ac": "P33309-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Glu23", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Does not affect the No-Go Decay (NGD) pathway.", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" }, { "database": "PubMed", "id": "19420139", "url": "https://glygen.org/publication/PubMed/19420139" } ] } ] }, { "uniprot_canonical_ac": "P33309-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Glu26", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Does not affect the No-Go Decay (NGD) pathway.", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" }, { "database": "PubMed", "id": "19420139", "url": "https://glygen.org/publication/PubMed/19420139" } ] } ] }, { "uniprot_canonical_ac": "P33309-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Asp27", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduced No-Go Decay (NGD) pathway.", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" }, { "database": "PubMed", "id": "19420139", "url": "https://glygen.org/publication/PubMed/19420139" } ] } ] }, { "uniprot_canonical_ac": "P33309-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Tyr300", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Reduced ability to trigger the No-Go Decay (NGD) pathway, reduced ability to promote degradation of non-functional rRNAs; when associated with A-361.", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" }, { "database": "PubMed", "id": "21102444", "url": "https://glygen.org/publication/PubMed/21102444" } ] } ] }, { "uniprot_canonical_ac": "P33309-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Glu361", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Reduced ability to trigger the No-Go Decay (NGD) pathway, reduced ability to promote degradation of non-functional rRNAs; when associated with A-300.", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" }, { "database": "PubMed", "id": "21102444", "url": "https://glygen.org/publication/PubMed/21102444" } ] }, { "sequence_org": "E", "sequence_mut": "R", "comment": "Reduced ability to trigger the No-Go Decay (NGD) pathway, reduced ability to promote degradation of non-functional rRNAs.", "evidence": [ { "database": "UniProtKB", "id": "P33309", "url": "https://www.uniprot.org/uniprotkb/P33309" }, { "database": "PubMed", "id": "21102444", "url": "https://glygen.org/publication/PubMed/21102444" } ] } ] } ], "record_id": "P33309-1" }, { "uniprot_canonical_ac": "P40487-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 425, "chemical_mass": 48311.0, "gene_names": "DPH1;DPH1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "disease": [ { "disease_id": "DOID:0060469", "name": "Miller-Dieker lissencephaly syndrome", "description": "A syndrome characterized by classical lissencephaly and distinct facial features and has_material_basis_in submicroscopic deletions of 17p13.3, including the LIS1 gene.", "url": "https://disease-ontology.org/term/DOID:0060469", "evidence": [ { "id": "0060469", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060469" } ], "weight": 0.0 }, { "disease_id": "DOID:0070476", "name": "diphthamide deficiency syndrome", "description": "An inherited metabolic disorder characterized by global developmental delay, short stature, dysmorphic craniofacial features, and sparse hair that has_material_basis_in deficient diphthamidylation of the eukaryotic translation Elongation Factor 2 protein (gene: EEF2).", "url": "https://disease-ontology.org/term/DOID:0070476", "evidence": [ { "id": "0070476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070476" } ], "weight": 0.0 }, { "disease_id": "DOID:0070477", "name": "diphthamide deficiency syndrome 1", "description": "A diphthamide deficiency syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the DPH1 gene on chromosome 17p13.3.", "url": "https://disease-ontology.org/term/DOID:0070477", "evidence": [ { "id": "0070477", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070477" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" } ], "pmid": "" }, { "name": "2-(3-amino-3-carboxypropyl)histidine synthase complex", "id": "GO:0120513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120513", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" } ], "pmid": "" }, { "name": "2-(3-amino-3-carboxypropyl)histidine synthase activity", "id": "GO:0090560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090560", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" } ], "pmid": "" } ], "biological_process": [ { "name": "protein histidyl modification to diphthamide", "id": "GO:0017183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017183", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40487-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Thr340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40487", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40487" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P40487-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P40487", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40487" } ] } ] }, { "uniprot_canonical_ac": "P40487-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Cys133", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Resistance to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Resistance to diphtheria toxin.", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] }, { "uniprot_canonical_ac": "P40487-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Cys239", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Resistance to diphtheria toxin. Abolishes [4Fe-4S] cluster binding and catalytic activity; when associated with S-368.", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Resistance to diphtheria toxin. Abolishes [4Fe-4S] cluster binding and catalytic activity; when associated with S-368.", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] }, { "uniprot_canonical_ac": "P40487-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Cys368", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Resistance to diphtheria toxin. Abolishes [4Fe-4S] cluster binding and catalytic activity; when associated with S-239.", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Resistance to diphtheria toxin. Abolishes [4Fe-4S] cluster binding and catalytic activity; when associated with S-239.", "evidence": [ { "database": "UniProtKB", "id": "P40487", "url": "https://www.uniprot.org/uniprotkb/P40487" }, { "database": "PubMed", "id": "31463593", "url": "https://glygen.org/publication/PubMed/31463593" } ] } ] } ], "record_id": "P40487-1" }, { "uniprot_canonical_ac": "P41807-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41807", "url": "https://www.uniprot.org/uniprotkb/P41807" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 478, "chemical_mass": 54416.0, "gene_names": "VMA13;CLS11;VMA13;YP3085.02", "protein_name": "V-type proton ATPase subunit H", "disease": [ { "disease_id": "DOID:11476", "name": "osteoporosis", "description": "A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.", "url": "https://disease-ontology.org/term/DOID:11476", "evidence": [ { "id": "11476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11476" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P41807", "url": "https://www.uniprot.org/uniprotkb/P41807" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V1 domain", "id": "GO:0000221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000221", "evidence": [ { "database": "UniProtKB", "id": "P41807", "url": "https://www.uniprot.org/uniprotkb/P41807" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P41807", "url": "https://www.uniprot.org/uniprotkb/P41807" } ], "pmid": "" } ], "biological_process": [ { "name": "endosomal lumen acidification", "id": "GO:0048388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048388", "evidence": [ { "database": "UniProtKB", "id": "P41807", "url": "https://www.uniprot.org/uniprotkb/P41807" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "P41807", "url": "https://www.uniprot.org/uniprotkb/P41807" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "P41807", "url": "https://www.uniprot.org/uniprotkb/P41807" } ], "pmid": "" }, { "name": "Golgi lumen acidification", "id": "GO:0061795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061795", "evidence": [ { "database": "UniProtKB", "id": "P41807", "url": "https://www.uniprot.org/uniprotkb/P41807" } ], "pmid": "" } ], "molecular_function": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "P41807", "url": "https://www.uniprot.org/uniprotkb/P41807" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41807-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Thr11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006240", "url": "https://www.yeastgenome.org/locus/S000006240" }, { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006240", "url": "https://www.yeastgenome.org/locus/S000006240" }, { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006240", "url": "https://www.yeastgenome.org/locus/S000006240" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "459", "end_pos": "459", "site_lbl": "Ser459", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006240", "url": "https://www.yeastgenome.org/locus/S000006240" }, { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006240", "url": "https://www.yeastgenome.org/locus/S000006240" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006240", "url": "https://www.yeastgenome.org/locus/S000006240" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Ser62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006240", "url": "https://www.yeastgenome.org/locus/S000006240" }, { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006240", "url": "https://www.yeastgenome.org/locus/S000006240" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006240", "url": "https://www.yeastgenome.org/locus/S000006240" }, { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41807" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P41807-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Asp410", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Appears to have no effect on the ATPase activity of membrane-detached V-ATPase V1 or on cell population growth.", "evidence": [ { "database": "UniProtKB", "id": "P41807", "url": "https://www.uniprot.org/uniprotkb/P41807" }, { "database": "PubMed", "id": "27295975", "url": "https://glygen.org/publication/PubMed/27295975" } ] } ] } ], "record_id": "P41807-1" }, { "uniprot_canonical_ac": "P53622-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53622", "url": "https://www.uniprot.org/uniprotkb/P53622" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1201, "chemical_mass": 135607.0, "gene_names": "COP1;COP1;D1578;RET1;SEC33;SOO1", "protein_name": "Coatomer subunit alpha", "disease": [ { "disease_id": "DOID:0081242", "name": "autoimmune interstitial lung, joint, and kidney disease", "description": "An autoimmune disease that is characterized by interstitial lung disease, inflammatory arthritis, and immune complex-mediated renal disease and that has_material_basis_in heterozygous mutation in the COPA gene on chromosome 1q23.", "url": "https://disease-ontology.org/term/DOID:0081242", "evidence": [ { "id": "0081242", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081242" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P53622", "url": "https://www.uniprot.org/uniprotkb/P53622" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "P53622", "url": "https://www.uniprot.org/uniprotkb/P53622" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P53622", "url": "https://www.uniprot.org/uniprotkb/P53622" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P53622", "url": "https://www.uniprot.org/uniprotkb/P53622" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "P53622", "url": "https://www.uniprot.org/uniprotkb/P53622" } ], "pmid": "" }, { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "P53622", "url": "https://www.uniprot.org/uniprotkb/P53622" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P53622", "url": "https://www.uniprot.org/uniprotkb/P53622" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "P53622", "url": "https://www.uniprot.org/uniprotkb/P53622" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "P53622", "url": "https://www.uniprot.org/uniprotkb/P53622" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53622-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Ser180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Thr286", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" }, { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "357", "end_pos": "357", "site_lbl": "Ser357", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" }, { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" }, { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Thr599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" }, { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "750", "end_pos": "750", "site_lbl": "Ser750", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" }, { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "751", "end_pos": "751", "site_lbl": "Ser751", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" }, { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "956", "end_pos": "956", "site_lbl": "Ser956", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "957", "end_pos": "957", "site_lbl": "Thr957", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "974", "end_pos": "974", "site_lbl": "Thr974", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" }, { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53622-1", "start_pos": "976", "end_pos": "976", "site_lbl": "Ser976", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002304", "url": "https://www.yeastgenome.org/locus/S000002304" }, { "database": "iPTMnet", "id": "P53622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53622" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53622-1" }, { "uniprot_canonical_ac": "P40005-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40005", "url": "https://www.uniprot.org/uniprotkb/P40005" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 111, "chemical_mass": 12994.0, "gene_names": "GIM4;GIM4;PFD2", "protein_name": "Prefoldin subunit 2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40005", "url": "https://www.uniprot.org/uniprotkb/P40005" } ], "pmid": "" }, { "name": "prefoldin complex", "id": "GO:0016272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016272", "evidence": [ { "database": "UniProtKB", "id": "P40005", "url": "https://www.uniprot.org/uniprotkb/P40005" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P40005", "url": "https://www.uniprot.org/uniprotkb/P40005" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "P40005", "url": "https://www.uniprot.org/uniprotkb/P40005" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "P40005", "url": "https://www.uniprot.org/uniprotkb/P40005" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P40005", "url": "https://www.uniprot.org/uniprotkb/P40005" } ], "pmid": "" }, { "name": "tubulin complex assembly", "id": "GO:0007021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007021", "evidence": [ { "database": "UniProtKB", "id": "P40005", "url": "https://www.uniprot.org/uniprotkb/P40005" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40005-1" }, { "uniprot_canonical_ac": "Q04969-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04969", "url": "https://www.uniprot.org/uniprotkb/Q04969" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 178, "chemical_mass": 20802.0, "gene_names": "SPC2;SPC2;SPY1;YM9958.07", "protein_name": "Signal peptidase complex subunit 2", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q04969", "url": "https://www.uniprot.org/uniprotkb/Q04969" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q04969", "url": "https://www.uniprot.org/uniprotkb/Q04969" } ], "pmid": "" }, { "name": "signal peptidase complex", "id": "GO:0005787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005787", "evidence": [ { "database": "UniProtKB", "id": "Q04969", "url": "https://www.uniprot.org/uniprotkb/Q04969" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "Q04969", "url": "https://www.uniprot.org/uniprotkb/Q04969" } ], "pmid": "" }, { "name": "signal peptide processing", "id": "GO:0006465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006465", "evidence": [ { "database": "UniProtKB", "id": "Q04969", "url": "https://www.uniprot.org/uniprotkb/Q04969" } ], "pmid": "" }, { "name": "negative regulation of post-translational protein targeting to membrane, translocation", "id": "GO:0120236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120236", "evidence": [ { "database": "UniProtKB", "id": "Q04969", "url": "https://www.uniprot.org/uniprotkb/Q04969" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q04969-1" }, { "uniprot_canonical_ac": "P25443-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 254, "chemical_mass": 27450.0, "gene_names": "RPS2;G2893;RPS2;RPS4;SUP138;SUP38;SUP44", "protein_name": "Small ribosomal subunit protein uS5", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" }, { "name": "positive regulation of translational fidelity", "id": "GO:0045903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045903", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" }, { "name": "small ribosomal subunit rRNA binding", "id": "GO:0070181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070181", "evidence": [ { "database": "UniProtKB", "id": "P25443", "url": "https://www.uniprot.org/uniprotkb/P25443" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P25443-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P25443-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Thr146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P25443-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P25443-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P25443-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P25443-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Thr206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P25443-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Ser238", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "17545469", "url": "https://glygen.org/publication/PubMed/17545469" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P25443-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Tyr243", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P25443-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Ser244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P25443-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Ser248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P25443-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P25443", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25443" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003091", "url": "https://www.yeastgenome.org/locus/S000003091" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P25443-1" }, { "uniprot_canonical_ac": "P26321-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 297, "chemical_mass": 33715.0, "gene_names": "RPL5;LPI14W;LPI14;RPL1A;RPL1;RPL5", "protein_name": "Large ribosomal subunit protein uL18", "disease": [ { "disease_id": "DOID:0060036", "name": "intrinsic cardiomyopathy", "description": "A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause.", "url": "https://disease-ontology.org/term/DOID:0060036", "evidence": [ { "id": "0060036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060036" } ], "weight": 0.0 }, { "disease_id": "DOID:0111879", "name": "Diamond-Blackfan anemia 6", "description": "A Diamond-Blackfan anemia that has_material_basis_in heterozygous mutation in the RPL5 gene on chromosome 1p22.1.", "url": "https://disease-ontology.org/term/DOID:0111879", "evidence": [ { "id": "0111879", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111879" } ], "weight": 0.0 }, { "disease_id": "DOID:1339", "name": "Diamond-Blackfan anemia", "description": "A pure red-cell aplasia that is characterized by anemia (low red blood cell counts) with decreased erythroid progenitors in the bone marrow and has_material_basis_insufficient levels of red blood cells due to bone marrow dysfunction.", "url": "https://disease-ontology.org/term/DOID:1339", "evidence": [ { "id": "1339", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1339" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:5603", "name": "T-cell acute lymphoblastic leukemia", "description": "An acute lymphoblastic leukemia that is characterized by too many T-cell lymphoblasts found in the bone marrow and blood.", "url": "https://disease-ontology.org/term/DOID:5603", "evidence": [ { "id": "5603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5603" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" } ], "pmid": "" } ], "molecular_function": [ { "name": "5S rRNA binding", "id": "GO:0008097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008097", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P26321-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Thr118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Thr132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Thr153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Thr154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Thr155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Tyr172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Thr18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P26321", "url": "https://www.uniprot.org/uniprotkb/P26321" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Thr256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Thr261", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Ser278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P26321-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006052", "url": "https://www.yeastgenome.org/locus/S000006052" }, { "database": "iPTMnet", "id": "P26321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P26321" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P26321-1" }, { "uniprot_canonical_ac": "P46965-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46965", "url": "https://www.uniprot.org/uniprotkb/P46965" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 94, "chemical_mass": 10819.0, "gene_names": "SPC1;SPC1;YJR010BW", "protein_name": "Signal peptidase complex subunit 1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P46965", "url": "https://www.uniprot.org/uniprotkb/P46965" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P46965", "url": "https://www.uniprot.org/uniprotkb/P46965" } ], "pmid": "" }, { "name": "signal peptidase complex", "id": "GO:0005787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005787", "evidence": [ { "database": "UniProtKB", "id": "P46965", "url": "https://www.uniprot.org/uniprotkb/P46965" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "P46965", "url": "https://www.uniprot.org/uniprotkb/P46965" } ], "pmid": "" }, { "name": "signal peptide processing", "id": "GO:0006465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006465", "evidence": [ { "database": "UniProtKB", "id": "P46965", "url": "https://www.uniprot.org/uniprotkb/P46965" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P46965-1" }, { "uniprot_canonical_ac": "Q02892-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 647, "chemical_mass": 74410.0, "gene_names": "NOG1;LPG15W;NOG1", "protein_name": "Nucleolar GTP-binding protein 1", "disease": [ { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "pmid": "" }, { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "pmid": "" }, { "name": "assembly of large subunit precursor of preribosome", "id": "GO:1902626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902626", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02892-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Ser350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Thr375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Ser381", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Ser471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "478", "end_pos": "478", "site_lbl": "Tyr478", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ser484", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "558", "end_pos": "558", "site_lbl": "Tyr558", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "563", "end_pos": "563", "site_lbl": "Ser563", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02892", "url": "https://www.uniprot.org/uniprotkb/Q02892" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "574", "end_pos": "574", "site_lbl": "Thr574", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "576", "end_pos": "576", "site_lbl": "Ser576", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Thr577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "597", "end_pos": "597", "site_lbl": "Ser597", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02892-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006014", "url": "https://www.yeastgenome.org/locus/S000006014" }, { "database": "iPTMnet", "id": "Q02892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "Q02892-1" }, { "uniprot_canonical_ac": "P11986-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 533, "chemical_mass": 59642.0, "gene_names": "INO1;APR1;INO1;J0610", "protein_name": "Inositol-3-phosphate synthase", "disease": [ { "disease_id": "DOID:0060158", "name": "acquired metabolic disease", "description": "A disease of metabolism that has_material_basis_in enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to an endocrine organ disease, organ malfunction, inadequate intake, dietary deficiency, or malabsorption.", "url": "https://disease-ontology.org/term/DOID:0060158", "evidence": [ { "id": "0060158", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060158" } ], "weight": 0.0 }, { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" } ], "pmid": "" } ], "biological_process": [ { "name": "inositol biosynthetic process", "id": "GO:0006021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006021", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" } ], "pmid": "" }, { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" } ], "pmid": "" } ], "molecular_function": [ { "name": "inositol-3-phosphate synthase activity", "id": "GO:0004512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004512", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P11986-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003689", "url": "https://www.yeastgenome.org/locus/S000003689" }, { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "23902760", "url": "https://glygen.org/publication/PubMed/23902760" }, { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "23902760", "url": "https://glygen.org/publication/PubMed/23902760" }, { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "D", "comment": "Decreases activity. Inositol auxotrophy.", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "23902760", "url": "https://glygen.org/publication/PubMed/23902760" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Ser254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003689", "url": "https://www.yeastgenome.org/locus/S000003689" }, { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Ser296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "23902760", "url": "https://glygen.org/publication/PubMed/23902760" }, { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Decreases activity. Inositol auxotrophy.", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "23902760", "url": "https://glygen.org/publication/PubMed/23902760" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Decreases activity. Inositol auxotrophy.", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "23902760", "url": "https://glygen.org/publication/PubMed/23902760" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003689", "url": "https://www.yeastgenome.org/locus/S000003689" }, { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Ser330", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003689", "url": "https://www.yeastgenome.org/locus/S000003689" }, { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Ser368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Ser374", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "23902760", "url": "https://glygen.org/publication/PubMed/23902760" }, { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "D", "comment": "Decreases activity. Inositol auxotrophy.", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "23902760", "url": "https://glygen.org/publication/PubMed/23902760" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Thr40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003689", "url": "https://www.yeastgenome.org/locus/S000003689" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Ser42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003689", "url": "https://www.yeastgenome.org/locus/S000003689" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Thr48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "23902760", "url": "https://glygen.org/publication/PubMed/23902760" }, { "database": "iPTMnet", "id": "P11986", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11986" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003689", "url": "https://www.yeastgenome.org/locus/S000003689" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Lys369", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "14684747", "url": "https://glygen.org/publication/PubMed/14684747" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Lys412", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "14684747", "url": "https://glygen.org/publication/PubMed/14684747" } ] } ] }, { "uniprot_canonical_ac": "P11986-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Lys489", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P11986", "url": "https://www.uniprot.org/uniprotkb/P11986" }, { "database": "PubMed", "id": "14684747", "url": "https://glygen.org/publication/PubMed/14684747" } ] } ] } ], "record_id": "P11986-1" }, { "uniprot_canonical_ac": "P40106-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40106", "url": "https://www.uniprot.org/uniprotkb/P40106" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 250, "chemical_mass": 27814.0, "gene_names": "GPP2;GPP2;HOR2", "protein_name": "Glycerol-1-phosphate phosphohydrolase 2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40106", "url": "https://www.uniprot.org/uniprotkb/P40106" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40106", "url": "https://www.uniprot.org/uniprotkb/P40106" } ], "pmid": "" } ], "biological_process": [ { "name": "response to osmotic stress", "id": "GO:0006970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006970", "evidence": [ { "database": "UniProtKB", "id": "P40106", "url": "https://www.uniprot.org/uniprotkb/P40106" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "P40106", "url": "https://www.uniprot.org/uniprotkb/P40106" } ], "pmid": "" }, { "name": "glycerol biosynthetic process", "id": "GO:0006114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006114", "evidence": [ { "database": "UniProtKB", "id": "P40106", "url": "https://www.uniprot.org/uniprotkb/P40106" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P40106", "url": "https://www.uniprot.org/uniprotkb/P40106" } ], "pmid": "" }, { "name": "sn-glycerol 1-phosphatase activity", "id": "GO:0000121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000121", "evidence": [ { "database": "UniProtKB", "id": "P40106", "url": "https://www.uniprot.org/uniprotkb/P40106" } ], "pmid": "" }, { "name": "sn-glycerol 3-phosphatase activity", "id": "GO:0043136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043136", "evidence": [ { "database": "UniProtKB", "id": "P40106", "url": "https://www.uniprot.org/uniprotkb/P40106" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40106-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Thr115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40106" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000864", "url": "https://www.yeastgenome.org/locus/S000000864" } ] } ] }, { "uniprot_canonical_ac": "P40106-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40106" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000864", "url": "https://www.yeastgenome.org/locus/S000000864" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40106-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Thr118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40106" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000864", "url": "https://www.yeastgenome.org/locus/S000000864" } ] } ] }, { "uniprot_canonical_ac": "P40106-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40106", "url": "https://www.uniprot.org/uniprotkb/P40106" }, { "database": "SGD", "id": "S000000864", "url": "https://www.yeastgenome.org/locus/S000000864" }, { "database": "iPTMnet", "id": "P40106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40106" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40106-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000864", "url": "https://www.yeastgenome.org/locus/S000000864" }, { "database": "iPTMnet", "id": "P40106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40106" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40106-1" }, { "uniprot_canonical_ac": "P40107-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 337, "chemical_mass": 37019.0, "gene_names": "VRG4;GOG5;LDB3;MCD3;VAN2;VIG4;VRG4", "protein_name": "GDP-mannose transporter 1", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" } ], "pmid": "" } ], "molecular_function": [ { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" } ], "pmid": "" }, { "name": "GDP-mannose transmembrane transporter activity", "id": "GO:0005458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005458", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" } ], "pmid": "" } ], "biological_process": [ { "name": "GDP-mannose transmembrane transport", "id": "GO:1990570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990570", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40107-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Asn119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 119, "start_aa": "Asn", "end_pos": 119, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn119", "evidence": [ { "id": "P40107", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40107#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Asn242", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 242, "start_aa": "Asn", "end_pos": 242, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn242", "evidence": [ { "id": "P40107", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40107#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Asn246", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 246, "start_aa": "Asn", "end_pos": 246, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn246", "evidence": [ { "id": "P40107", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40107#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Asn249", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 249, "start_aa": "Asn", "end_pos": 249, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn249", "evidence": [ { "id": "P40107", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40107#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Ser278", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "C", "comment": "In VIG4-2; increases drug sensitivity and decreases protein glycolysis.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "10570930", "url": "https://glygen.org/publication/PubMed/10570930" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Thr280", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Decreases transport activity and GDP-mannose-binding.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "11067855", "url": "https://glygen.org/publication/PubMed/11067855" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Decreases transport activity and GDP-mannose-binding.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "11067855", "url": "https://glygen.org/publication/PubMed/11067855" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Gly285", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Decreases transport activity and GDP-mannose-binding.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "11067855", "url": "https://glygen.org/publication/PubMed/11067855" } ] }, { "sequence_org": "G", "sequence_mut": "D", "comment": "Decreases transport activity and GDP-mannose-binding.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "11067855", "url": "https://glygen.org/publication/PubMed/11067855" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Ala286", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "V", "comment": "In VIG4-1; increases drug sensitivity and decreases protein glycolysis.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "11067855", "url": "https://glygen.org/publication/PubMed/11067855" }, { "database": "PubMed", "id": "10570930", "url": "https://glygen.org/publication/PubMed/10570930" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Leu287", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Decreases transport activity and GDP-mannose-binding.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "11067855", "url": "https://glygen.org/publication/PubMed/11067855" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Asn288", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Decreases transport activity and GDP-mannose-binding.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "11067855", "url": "https://glygen.org/publication/PubMed/11067855" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Lys289", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Decreases transport activity and GDP-mannose-binding.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "11067855", "url": "https://glygen.org/publication/PubMed/11067855" } ] }, { "sequence_org": "K", "sequence_mut": "D", "comment": "Decreases transport activity and GDP-mannose-binding.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "11067855", "url": "https://glygen.org/publication/PubMed/11067855" } ] } ] }, { "uniprot_canonical_ac": "P40107-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Pro291", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "Decreases transport activity and GDP-mannose-binding.", "evidence": [ { "database": "UniProtKB", "id": "P40107", "url": "https://www.uniprot.org/uniprotkb/P40107" }, { "database": "PubMed", "id": "11067855", "url": "https://glygen.org/publication/PubMed/11067855" } ] } ] } ], "record_id": "P40107-1" }, { "uniprot_canonical_ac": "P40150-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 613, "chemical_mass": 66595.0, "gene_names": "SSB2;N1333;SSB2;YG103", "protein_name": "Ribosome-associated molecular chaperone SSB2", "disease": [], "biological_process": [ { "name": "'de novo' cotranslational protein folding", "id": "GO:0051083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051083", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "translational frameshifting", "id": "GO:0006452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006452", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40150-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Thr40", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Thr115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Tyr151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Tyr185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Thr252", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Ser289", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Thr301", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Ser315", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Thr316", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Ser332", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Ser343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "422", "end_pos": "422", "site_lbl": "Thr422", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "423", "end_pos": "423", "site_lbl": "Thr423", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Thr426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Thr431", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Thr434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "440", "end_pos": "440", "site_lbl": "Thr440", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Thr441", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Thr458", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Thr47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40150", "url": "https://www.uniprot.org/uniprotkb/P40150" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "502", "end_pos": "502", "site_lbl": "Ser502", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Ser503", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Thr506", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "508", "end_pos": "508", "site_lbl": "Ser508", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Ser515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "516", "end_pos": "516", "site_lbl": "Ser516", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "548", "end_pos": "548", "site_lbl": "Ser548", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "549", "end_pos": "549", "site_lbl": "Tyr549", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "572", "end_pos": "572", "site_lbl": "Ser572", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "591", "end_pos": "591", "site_lbl": "Ser591", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40150-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40150" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000005153", "url": "https://www.yeastgenome.org/locus/S000005153" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P40150-1" }, { "uniprot_canonical_ac": "P40152-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 326, "chemical_mass": 37151.0, "gene_names": "PPN2;N1306;PPN2", "protein_name": "Zinc-dependent endopolyphosphatase", "disease": [], "molecular_function": [ { "name": "endopolyphosphatase activity", "id": "GO:0000298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000298", "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" } ], "pmid": "" }, { "name": "vacuolar lumen", "id": "GO:0005775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005775", "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" } ], "pmid": "" } ], "biological_process": [ { "name": "polyphosphate catabolic process", "id": "GO:0006798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006798", "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" } ], "pmid": "" }, { "name": "cellular response to phosphate starvation", "id": "GO:0016036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016036", "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40152-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Asn241", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 241, "start_aa": "Asn", "end_pos": 241, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn241", "evidence": [ { "id": "P40152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40152#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P40152-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Asn90", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 90, "start_aa": "Asn", "end_pos": 90, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn90", "evidence": [ { "id": "P40152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40152#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P40152-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Asp68", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Almost completely abolishes polyphosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" }, { "database": "PubMed", "id": "28302909", "url": "https://glygen.org/publication/PubMed/28302909" } ] } ] }, { "uniprot_canonical_ac": "P40152-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Asp98", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Almost completely abolishes polyphosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "P40152", "url": "https://www.uniprot.org/uniprotkb/P40152" }, { "database": "PubMed", "id": "28302909", "url": "https://glygen.org/publication/PubMed/28302909" } ] } ] } ], "record_id": "P40152-1" }, { "uniprot_canonical_ac": "P40155-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40155", "url": "https://www.uniprot.org/uniprotkb/P40155" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 199, "chemical_mass": 23169.0, "gene_names": "PEX17;N1319;PAS9;PEX17", "protein_name": "Peroxisomal membrane protein PEX17", "disease": [], "biological_process": [ { "name": "protein import into peroxisome matrix, translocation", "id": "GO:0016561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016561", "evidence": [ { "database": "UniProtKB", "id": "P40155", "url": "https://www.uniprot.org/uniprotkb/P40155" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix, docking", "id": "GO:0016560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016560", "evidence": [ { "database": "UniProtKB", "id": "P40155", "url": "https://www.uniprot.org/uniprotkb/P40155" } ], "pmid": "" } ], "cellular_component": [ { "name": "peroxisomal importomer complex", "id": "GO:1990429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990429", "evidence": [ { "database": "UniProtKB", "id": "P40155", "url": "https://www.uniprot.org/uniprotkb/P40155" } ], "pmid": "" }, { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "P40155", "url": "https://www.uniprot.org/uniprotkb/P40155" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40155-1" }, { "uniprot_canonical_ac": "P40167-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40167", "url": "https://www.uniprot.org/uniprotkb/P40167" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 298, "chemical_mass": 34318.0, "gene_names": "SLZ1;N1386;SLZ1", "protein_name": "Sporulation-specific with a leucine zipper motif protein 1", "disease": [], "cellular_component": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "P40167", "url": "https://www.uniprot.org/uniprotkb/P40167" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P40167", "url": "https://www.uniprot.org/uniprotkb/P40167" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40167", "url": "https://www.uniprot.org/uniprotkb/P40167" } ], "pmid": "" } ], "biological_process": [ { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P40167", "url": "https://www.uniprot.org/uniprotkb/P40167" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P40167", "url": "https://www.uniprot.org/uniprotkb/P40167" } ], "pmid": "" }, { "name": "negative regulation of pseudohyphal growth", "id": "GO:2000221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000221", "evidence": [ { "database": "UniProtKB", "id": "P40167", "url": "https://www.uniprot.org/uniprotkb/P40167" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40167-1" }, { "uniprot_canonical_ac": "P40204-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 77, "chemical_mass": 8482.0, "gene_names": "SMX2;SMX2;SNP2;YFL017Bw;YFL018W-A", "protein_name": "Small nuclear ribonucleoprotein G", "disease": [ { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "U4 snRNP", "id": "GO:0005687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005687", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "SMN-Sm protein complex", "id": "GO:0034719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034719", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "spliceosomal tri-snRNP complex", "id": "GO:0097526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097526", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" } ], "biological_process": [ { "name": "7-methylguanosine cap hypermethylation", "id": "GO:0036261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036261", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P40204", "url": "https://www.uniprot.org/uniprotkb/P40204" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40204-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002965", "url": "https://www.yeastgenome.org/locus/S000002965" }, { "database": "iPTMnet", "id": "P40204", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40204" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40204-1" }, { "uniprot_canonical_ac": "P40208-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40208", "url": "https://www.uniprot.org/uniprotkb/P40208" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 455, "chemical_mass": 51729.0, "gene_names": "GID8;DCR1;GID8;YM9375.04C", "protein_name": "GID complex subunit 8", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40208", "url": "https://www.uniprot.org/uniprotkb/P40208" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40208", "url": "https://www.uniprot.org/uniprotkb/P40208" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40208", "url": "https://www.uniprot.org/uniprotkb/P40208" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "P40208", "url": "https://www.uniprot.org/uniprotkb/P40208" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "P40208", "url": "https://www.uniprot.org/uniprotkb/P40208" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P40208", "url": "https://www.uniprot.org/uniprotkb/P40208" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P40208", "url": "https://www.uniprot.org/uniprotkb/P40208" } ], "pmid": "" }, { "name": "negative regulation of gluconeogenesis", "id": "GO:0045721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045721", "evidence": [ { "database": "UniProtKB", "id": "P40208", "url": "https://www.uniprot.org/uniprotkb/P40208" } ], "pmid": "" }, { "name": "traversing start control point of mitotic cell cycle", "id": "GO:0007089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007089", "evidence": [ { "database": "UniProtKB", "id": "P40208", "url": "https://www.uniprot.org/uniprotkb/P40208" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40208-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Thr10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004742", "url": "https://www.yeastgenome.org/locus/S000004742" }, { "database": "iPTMnet", "id": "P40208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40208" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40208-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Ser349", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004742", "url": "https://www.yeastgenome.org/locus/S000004742" }, { "database": "iPTMnet", "id": "P40208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40208" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40208-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004742", "url": "https://www.yeastgenome.org/locus/S000004742" }, { "database": "iPTMnet", "id": "P40208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40208" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40208-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004742", "url": "https://www.yeastgenome.org/locus/S000004742" }, { "database": "iPTMnet", "id": "P40208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40208" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40208-1" }, { "uniprot_canonical_ac": "P40215-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40215", "url": "https://www.uniprot.org/uniprotkb/P40215" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 560, "chemical_mass": 62774.0, "gene_names": "NDE1;NDE1;NDH1;YM9375.14C", "protein_name": "External NADH-ubiquinone oxidoreductase 1, mitochondrial", "disease": [], "molecular_function": [ { "name": "NADH dehydrogenase activity", "id": "GO:0003954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003954", "evidence": [ { "database": "UniProtKB", "id": "P40215", "url": "https://www.uniprot.org/uniprotkb/P40215" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "P40215", "url": "https://www.uniprot.org/uniprotkb/P40215" } ], "pmid": "" }, { "name": "NADH dehydrogenase (ubiquinone) (non-electrogenic) activity", "id": "GO:0120555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120555", "evidence": [ { "database": "UniProtKB", "id": "P40215", "url": "https://www.uniprot.org/uniprotkb/P40215" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40215", "url": "https://www.uniprot.org/uniprotkb/P40215" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P40215", "url": "https://www.uniprot.org/uniprotkb/P40215" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "P40215", "url": "https://www.uniprot.org/uniprotkb/P40215" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "P40215", "url": "https://www.uniprot.org/uniprotkb/P40215" } ], "pmid": "" }, { "name": "glycolytic fermentation to ethanol", "id": "GO:0019655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019655", "evidence": [ { "database": "UniProtKB", "id": "P40215", "url": "https://www.uniprot.org/uniprotkb/P40215" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40215-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Thr285", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 285, "start_aa": "Thr", "end_pos": 285, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr285", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P40215-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Thr54", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 54, "start_aa": "Thr", "end_pos": 54, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr54", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P40215-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004753", "url": "https://www.yeastgenome.org/locus/S000004753" }, { "database": "iPTMnet", "id": "P40215", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40215" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40215-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ser484", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004753", "url": "https://www.yeastgenome.org/locus/S000004753" }, { "database": "iPTMnet", "id": "P40215", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40215" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40215-1" }, { "uniprot_canonical_ac": "P40308-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40308", "url": "https://www.uniprot.org/uniprotkb/P40308" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 642, "chemical_mass": 73613.0, "gene_names": "TGL3;TGL3;YM9924.05C", "protein_name": "Triacylglycerol lipase 3", "disease": [], "cellular_component": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P40308", "url": "https://www.uniprot.org/uniprotkb/P40308" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "P40308", "url": "https://www.uniprot.org/uniprotkb/P40308" } ], "pmid": "" }, { "name": "triglyceride catabolic process", "id": "GO:0019433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019433", "evidence": [ { "database": "UniProtKB", "id": "P40308", "url": "https://www.uniprot.org/uniprotkb/P40308" } ], "pmid": "" }, { "name": "cell budding", "id": "GO:0007114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007114", "evidence": [ { "database": "UniProtKB", "id": "P40308", "url": "https://www.uniprot.org/uniprotkb/P40308" } ], "pmid": "" } ], "molecular_function": [ { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "P40308", "url": "https://www.uniprot.org/uniprotkb/P40308" } ], "pmid": "" }, { "name": "lysophosphatidylethanolamine acyltransferase activity", "id": "GO:0071618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071618", "evidence": [ { "database": "UniProtKB", "id": "P40308", "url": "https://www.uniprot.org/uniprotkb/P40308" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40308-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Tyr129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40308", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40308" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004930", "url": "https://www.yeastgenome.org/locus/S000004930" } ] } ] }, { "uniprot_canonical_ac": "P40308-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Thr473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40308", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40308" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P40308-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Ser477", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004930", "url": "https://www.yeastgenome.org/locus/S000004930" }, { "database": "iPTMnet", "id": "P40308", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40308" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40308-1", "start_pos": "478", "end_pos": "478", "site_lbl": "Ser478", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40308", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40308" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004930", "url": "https://www.yeastgenome.org/locus/S000004930" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40308-1", "start_pos": "480", "end_pos": "480", "site_lbl": "Ser480", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40308", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40308" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004930", "url": "https://www.yeastgenome.org/locus/S000004930" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40308-1", "start_pos": "590", "end_pos": "590", "site_lbl": "Ser590", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004930", "url": "https://www.yeastgenome.org/locus/S000004930" }, { "database": "iPTMnet", "id": "P40308", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40308" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40308-1", "start_pos": "614", "end_pos": "614", "site_lbl": "Ser614", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40308", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40308" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40308-1", "start_pos": "615", "end_pos": "615", "site_lbl": "Thr615", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40308", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40308" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40308-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Ser237", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes TAG lipolytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P40308", "url": "https://www.uniprot.org/uniprotkb/P40308" }, { "database": "PubMed", "id": "16267052", "url": "https://glygen.org/publication/PubMed/16267052" } ] } ] } ], "record_id": "P40308-1" }, { "uniprot_canonical_ac": "P40316-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 373, "chemical_mass": 41838.0, "gene_names": "PDS1;PDS1;YD9727.08C", "protein_name": "Securin", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" }, { "name": "recombinational repair", "id": "GO:0000725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000725", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" }, { "name": "negative regulation of exit from mitosis", "id": "GO:0001100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001100", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" }, { "name": "meiosis I", "id": "GO:0007127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007127", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" }, { "name": "positive regulation of metaphase/anaphase transition of meiotic cell cycle", "id": "GO:1902104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902104", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40316-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "11390356", "url": "https://glygen.org/publication/PubMed/11390356" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Ser132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "11390356", "url": "https://glygen.org/publication/PubMed/11390356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "11390356", "url": "https://glygen.org/publication/PubMed/11390356" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Tyr156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "11390356", "url": "https://glygen.org/publication/PubMed/11390356" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Ser170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "11390356", "url": "https://glygen.org/publication/PubMed/11390356" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Ser212", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "11390356", "url": "https://glygen.org/publication/PubMed/11390356" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Ser213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "11390356", "url": "https://glygen.org/publication/PubMed/11390356" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" }, { "database": "PubMed", "id": "12050115", "url": "https://glygen.org/publication/PubMed/12050115" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Affects phosphorylation and the interaction with ESP1.", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" }, { "database": "PubMed", "id": "12050115", "url": "https://glygen.org/publication/PubMed/12050115" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "20421994", "url": "https://glygen.org/publication/PubMed/20421994" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Thr289", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "11390356", "url": "https://glygen.org/publication/PubMed/11390356" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" }, { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "12050115", "url": "https://glygen.org/publication/PubMed/12050115" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Affects phosphorylation and the interaction with ESP1.", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" }, { "database": "PubMed", "id": "12050115", "url": "https://glygen.org/publication/PubMed/12050115" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "11390356", "url": "https://glygen.org/publication/PubMed/11390356" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826" }, { "database": "PubMed", "id": "20421994", "url": "https://glygen.org/publication/PubMed/20421994" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40316" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002520", "url": "https://www.yeastgenome.org/locus/S000002520" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40316-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Thr304", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P40316", "url": "https://www.uniprot.org/uniprotkb/P40316" }, { "database": "PubMed", "id": "12050115", "url": "https://glygen.org/publication/PubMed/12050115" } ] } ] } ], "record_id": "P40316-1" }, { "uniprot_canonical_ac": "P40319-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 345, "chemical_mass": 39465.0, "gene_names": "ELO3;APA1;ELO3;L8039.2;SRE1;SUR4;VBM1", "protein_name": "Fatty acid elongase 3", "disease": [ { "disease_id": "DOID:0050981", "name": "spinocerebellar ataxia 34", "description": "An autosomal dominant cerebellar ataxia that is characterized by papulosquamous, ichthyosiform plaques at birth and progressive ataxia, dysarthria, nystagmus and hyporeflexia, has_material_basis_in mutation in the ELOVL4 gene.", "url": "https://disease-ontology.org/term/DOID:0050981", "evidence": [ { "id": "0050981", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050981" } ], "weight": 0.0 }, { "disease_id": "DOID:0050985", "name": "spinocerebellar ataxia 38", "description": "An autosomal dominant cerebellar ataxia that is characterized by slowly progressive ataxia and nystagmus, presenting in mid-adulthood, and has_material_basis_in mutation to the ELOVL5 gene.", "url": "https://disease-ontology.org/term/DOID:0050985", "evidence": [ { "id": "0050985", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050985" } ], "weight": 0.0 }, { "disease_id": "DOID:10588", "name": "adrenoleukodystrophy", "description": "A leukodystrophy that disrupts the breakdown of very-long-chain fatty acids resulting in progressive brain damage, failure of the adrenal glands and eventually death.", "url": "https://disease-ontology.org/term/DOID:10588", "evidence": [ { "id": "10588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10588" } ], "weight": 0.0 }, { "disease_id": "DOID:2566", "name": "corneal dystrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:2566", "evidence": [ { "id": "2566", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2566" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" }, { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" }, { "name": "post-Golgi vesicle-mediated transport", "id": "GO:0006892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006892", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" }, { "name": "fatty acid elongation", "id": "GO:0030497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030497", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" }, { "name": "fatty acid elongation, monounsaturated fatty acid", "id": "GO:0034625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034625", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" }, { "name": "fatty acid elongation, polyunsaturated fatty acid", "id": "GO:0034626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034626", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" }, { "name": "fatty acid elongation, saturated fatty acid", "id": "GO:0019367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019367", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" }, { "name": "very long-chain fatty acid biosynthetic process", "id": "GO:0042761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042761", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty acid elongase activity", "id": "GO:0009922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009922", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40319-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Asn20", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 20, "start_aa": "Asn", "end_pos": 20, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn20", "evidence": [ { "id": "P40319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40319#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P40319-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Asn2", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2, "start_aa": "Asn", "end_pos": 2, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2", "evidence": [ { "id": "P40319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40319#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P40319-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Asn66", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 66, "start_aa": "Asn", "end_pos": 66, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn66", "evidence": [ { "id": "P40319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40319#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P40319-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004364", "url": "https://www.yeastgenome.org/locus/S000004364" }, { "database": "iPTMnet", "id": "P40319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40319" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40319-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Ser322", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004364", "url": "https://www.yeastgenome.org/locus/S000004364" }, { "database": "iPTMnet", "id": "P40319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40319" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40319-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Ser324", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004364", "url": "https://www.yeastgenome.org/locus/S000004364" }, { "database": "iPTMnet", "id": "P40319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40319" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40319-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Ser327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40319" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004364", "url": "https://www.yeastgenome.org/locus/S000004364" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40319-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Ser329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004364", "url": "https://www.yeastgenome.org/locus/S000004364" }, { "database": "iPTMnet", "id": "P40319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40319" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40319-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Phe262", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "K", "comment": "Terminates elongation following the production of C22 instead of C-26; when associated with L-266.", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" }, { "database": "PubMed", "id": "17719544", "url": "https://glygen.org/publication/PubMed/17719544" } ] } ] }, { "uniprot_canonical_ac": "P40319-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Lys266", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "L", "comment": "Terminates elongation following the production of C22 instead of C-26; when associated with K-262.", "evidence": [ { "database": "UniProtKB", "id": "P40319", "url": "https://www.uniprot.org/uniprotkb/P40319" }, { "database": "PubMed", "id": "17719544", "url": "https://glygen.org/publication/PubMed/17719544" } ] } ] } ], "record_id": "P40319-1" }, { "uniprot_canonical_ac": "P40335-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 379, "chemical_mass": 42547.0, "gene_names": "PEP8;GRD6;J1152;PEP8;VPS26;VPT4", "protein_name": "Carboxypeptidase Y-deficient protein 8", "disease": [ { "disease_id": "DOID:1319", "name": "brain cancer", "description": "A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain.", "url": "https://disease-ontology.org/term/DOID:1319", "evidence": [ { "id": "1319", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1319" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "protein retention in Golgi apparatus", "id": "GO:0045053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045053", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" } ], "cellular_component": [ { "name": "retromer, cargo-selective complex", "id": "GO:0030906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030906", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" }, { "name": "CROP complex", "id": "GO:0170071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170071", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein transporter activity", "id": "GO:0140318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140318", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40335-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P40335-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003589", "url": "https://www.yeastgenome.org/locus/S000003589" }, { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40335-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003589", "url": "https://www.yeastgenome.org/locus/S000003589" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40335-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003589", "url": "https://www.yeastgenome.org/locus/S000003589" }, { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40335-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Tyr147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P40335-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P40335-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Tyr150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P40335-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Thr201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40335-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40335", "url": "https://www.uniprot.org/uniprotkb/P40335" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003589", "url": "https://www.yeastgenome.org/locus/S000003589" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40335-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Thr219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003589", "url": "https://www.yeastgenome.org/locus/S000003589" }, { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40335-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40335" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] } ], "record_id": "P40335-1" }, { "uniprot_canonical_ac": "P40340-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1379, "chemical_mass": 157407.0, "gene_names": "YTA7;YTA7", "protein_name": "ATPase histone chaperone YTA7", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "CENP-A containing chromatin assembly", "id": "GO:0034080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034080", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "positive regulation of invasive growth in response to glucose limitation", "id": "GO:2000219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000219", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "ATP-dependent histone chaperone activity", "id": "GO:0140674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140674", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40340-1", "start_pos": "445", "end_pos": "445", "site_lbl": "Thr445", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 445, "start_aa": "Thr", "end_pos": 445, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr445", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "34471130", "url": "https://glygen.org/publication/PubMed/34471130" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-94; A-212; A-230; A-241; A-259; A-285; A-304; A-369; A-370 and A-380.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "1016", "end_pos": "1016", "site_lbl": "Ser1016", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Thr106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "1142", "end_pos": "1142", "site_lbl": "Ser1142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "15972895", "url": "https://glygen.org/publication/PubMed/15972895" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "15972895", "url": "https://glygen.org/publication/PubMed/15972895" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-67; A-94; A-212; A-230; A-241; A-259; A-285; A-304; A-369; A-370; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "1206", "end_pos": "1206", "site_lbl": "Ser1206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "1256", "end_pos": "1256", "site_lbl": "Ser1256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "15972895", "url": "https://glygen.org/publication/PubMed/15972895" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "1259", "end_pos": "1259", "site_lbl": "Thr1259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "1262", "end_pos": "1262", "site_lbl": "Thr1262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "1284", "end_pos": "1284", "site_lbl": "Ser1284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "1290", "end_pos": "1290", "site_lbl": "Ser1290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "1301", "end_pos": "1301", "site_lbl": "Ser1301", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Ser190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Thr212", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34471130", "url": "https://glygen.org/publication/PubMed/34471130" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-94; A-230; A-241; A-259; A-285; A-304; A-369; A-370; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Thr229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-94; A-212; A-241; A-259; A-285; A-304; A-369; A-370; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Ser241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-94; A-212; A-230; A-259; A-285; A-304; A-369; A-370; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34471130", "url": "https://glygen.org/publication/PubMed/34471130" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-94; A-212; A-230; A-241; A-285; A-304; A-369; A-370; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-94; A-212; A-230; A-241; A-259; A-304; A-369; A-370; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Ser299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Ser304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34471130", "url": "https://glygen.org/publication/PubMed/34471130" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-94; A-212; A-230; A-241; A-259; A-285; A-369; A-370; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Ser316", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "15972895", "url": "https://glygen.org/publication/PubMed/15972895" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Ser356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-94; A-212; A-230; A-241; A-259; A-285; A-304; A-370; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-94; A-212; A-230; A-241; A-259; A-285; A-304; A-369; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Thr67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "34471130", "url": "https://glygen.org/publication/PubMed/34471130" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-94; A-212; A-230; A-241; A-259; A-285; A-304; A-369; A-370; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Thr72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "735", "end_pos": "735", "site_lbl": "Ser735", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Ser752", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "940", "end_pos": "940", "site_lbl": "Thr940", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "941", "end_pos": "941", "site_lbl": "Ser941", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34471130", "url": "https://glygen.org/publication/PubMed/34471130" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-212; A-230; A-241; A-259; A-285; A-304; A-369; A-370; A-380 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "967", "end_pos": "967", "site_lbl": "Ser967", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003502", "url": "https://www.yeastgenome.org/locus/S000003502" }, { "database": "iPTMnet", "id": "P40340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "380", "end_pos": "380", "site_lbl": "Thr380", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Severely decreases phosphorylation, causes a G2/M transition delay, and leads to sensitivity to 6-azauracil (impairs transcriptional elongation); when associated with A-11; A-67; A-94; A-212; A-230; A-241; A-259; A-285; A-304; A-369; A-370 and A-445.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] }, { "uniprot_canonical_ac": "P40340-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Lys460", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Increases YTA7 binding to the HTA1 open reading frame outside of S-phase. Increases localization of RTT106 and RSC8 to the HTA1 gene locus. Increases nucleosome occupancy at core histone loci. Decreases transcription of HTA1.", "evidence": [ { "database": "UniProtKB", "id": "P40340", "url": "https://www.uniprot.org/uniprotkb/P40340" }, { "database": "PubMed", "id": "22156209", "url": "https://glygen.org/publication/PubMed/22156209" } ] } ] } ], "record_id": "P40340-1" }, { "uniprot_canonical_ac": "P40341-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 825, "chemical_mass": 93276.0, "gene_names": "YTA12;RCA1;YM9582.14C;YTA12", "protein_name": "Mitochondrial inner membrane m-AAA protease component YTA12", "disease": [ { "disease_id": "DOID:0050944", "name": "spastic ataxia 5", "description": "A spastic ataxia that is characterized by early onset of cerebellar ataxia, spasticity, oculomotor apraxia, dystonia and myoclonic epilepsy, has_material_basis_in homozygous mutation in the AFG3L2 gene on chromosome 18p11.", "url": "https://disease-ontology.org/term/DOID:0050944", "evidence": [ { "id": "0050944", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050944" } ], "weight": 0.0 }, { "disease_id": "DOID:0050952", "name": "spastic ataxia", "description": "A hereditary ataxia that is characterized by early onset of cerebellar ataxia, pyramidal tract signs and peripheral neuropathy.", "url": "https://disease-ontology.org/term/DOID:0050952", "evidence": [ { "id": "0050952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050952" } ], "weight": 0.0 }, { "disease_id": "DOID:0050977", "name": "spinocerebellar ataxia 28", "description": "An autosomal dominant cerebellar ataxia that is characterized by progressive ataxia, dysarthria, hyperreflexia, ophthalmoparesis, nystagmus and ptosis, and has_material_basis_in mutation in the AFG3L2 gene.", "url": "https://disease-ontology.org/term/DOID:0050977", "evidence": [ { "id": "0050977", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050977" } ], "weight": 0.0 }, { "disease_id": "DOID:0080840", "name": "optic atrophy 12", "description": "An optic atrophy that is characterized by slowly progressive visual impairment with onset usually in the first decade and that has_material_basis_in heterozygous mutation in the AFG3L2 gene on chromosome 18p11.", "url": "https://disease-ontology.org/term/DOID:0080840", "evidence": [ { "id": "0080840", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080840" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.", "url": "https://disease-ontology.org/term/DOID:2476", "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "ATP-dependent peptidase activity", "id": "GO:0004176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004176", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "membrane protein dislocase activity", "id": "GO:0140567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140567", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "m-AAA complex", "id": "GO:0005745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005745", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "mitochondrial inner boundary membrane", "id": "GO:0097002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097002", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" } ], "biological_process": [ { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "mitochondrial protein processing", "id": "GO:0034982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034982", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "signal peptide processing", "id": "GO:0006465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006465", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40341-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Lys394", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Slightly impaired respiratory growth. Impaired maturation of CCP1.", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" }, { "database": "PubMed", "id": "19748354", "url": "https://glygen.org/publication/PubMed/19748354" } ] } ] }, { "uniprot_canonical_ac": "P40341-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Met420", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "K", "comment": "Slightly decreased ATPase activity, highly impaired maturation of CCP1.", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" }, { "database": "PubMed", "id": "17245427", "url": "https://glygen.org/publication/PubMed/17245427" } ] } ] }, { "uniprot_canonical_ac": "P40341-1", "start_pos": "421", "end_pos": "421", "site_lbl": "Phe421", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Decreased ATPase activity and maturation of CCP1.", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" }, { "database": "PubMed", "id": "17245427", "url": "https://glygen.org/publication/PubMed/17245427" } ] }, { "sequence_org": "F", "sequence_mut": "E", "comment": "Decreased ATPase activity and maturation of CCP1.", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" }, { "database": "PubMed", "id": "17245427", "url": "https://glygen.org/publication/PubMed/17245427" } ] } ] }, { "uniprot_canonical_ac": "P40341-1", "start_pos": "423", "end_pos": "423", "site_lbl": "Gly423", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Impaired maturation of CCP1.", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" }, { "database": "PubMed", "id": "17245427", "url": "https://glygen.org/publication/PubMed/17245427" } ] } ] }, { "uniprot_canonical_ac": "P40341-1", "start_pos": "448", "end_pos": "448", "site_lbl": "Glu448", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "Abolished ATPase activity, leading to impaired respiratory growth. Does not affect the protease activity.", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" }, { "database": "PubMed", "id": "19748354", "url": "https://glygen.org/publication/PubMed/19748354" } ] } ] }, { "uniprot_canonical_ac": "P40341-1", "start_pos": "614", "end_pos": "614", "site_lbl": "Glu614", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "Abolishes proteolytic activity; impairs synthesis of respiratory chain proteins COB and COX1. No effect on m-AAA protease assembly. Decreased ATPase activity and maturation of CCP1.", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" }, { "database": "PubMed", "id": "9707443", "url": "https://glygen.org/publication/PubMed/9707443" }, { "database": "PubMed", "id": "17245427", "url": "https://glygen.org/publication/PubMed/17245427" } ] } ] }, { "uniprot_canonical_ac": "P40341-1", "start_pos": "689", "end_pos": "689", "site_lbl": "Asp689", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Does not affect maturation of CCP1.", "evidence": [ { "database": "UniProtKB", "id": "P40341", "url": "https://www.uniprot.org/uniprotkb/P40341" }, { "database": "PubMed", "id": "17245427", "url": "https://glygen.org/publication/PubMed/17245427" } ] } ] } ], "record_id": "P40341-1" }, { "uniprot_canonical_ac": "P40345-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 661, "chemical_mass": 75393.0, "gene_names": "LRO1;LRO1;N2042", "protein_name": "Phospholipid:diacylglycerol acyltransferase", "disease": [ { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:1391", "name": "Norum disease", "description": "", "url": "https://disease-ontology.org/term/DOID:1391", "evidence": [ { "id": "1391", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1391" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide metabolic process", "id": "GO:0006672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006672", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" }, { "name": "triglyceride biosynthetic process", "id": "GO:0019432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019432", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" } ], "molecular_function": [ { "name": "O-acyltransferase activity", "id": "GO:0008374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008374", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" }, { "name": "phospholipid:diacylglycerol acyltransferase activity", "id": "GO:0046027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046027", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40345-1", "start_pos": "453", "end_pos": "453", "site_lbl": "Asn453", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 453, "start_aa": "Asn", "end_pos": 453, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn453", "evidence": [ { "id": "P40345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40345#ptm_processing" }, { "id": "30706417", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30706417" } ] } ] }, { "uniprot_canonical_ac": "P40345-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Asn461", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 461, "start_aa": "Asn", "end_pos": 461, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn461", "evidence": [ { "id": "P40345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40345#ptm_processing" }, { "id": "30706417", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30706417" } ] } ] }, { "uniprot_canonical_ac": "P40345-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Asn469", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 469, "start_aa": "Asn", "end_pos": 469, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn469", "evidence": [ { "id": "P40345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40345#ptm_processing" }, { "id": "30706417", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30706417" } ] } ] }, { "uniprot_canonical_ac": "P40345-1", "start_pos": "594", "end_pos": "594", "site_lbl": "Asn594", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 594, "start_aa": "Asn", "end_pos": 594, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn594", "evidence": [ { "id": "P40345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40345#ptm_processing" }, { "id": "30706417", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30706417" } ] } ] }, { "uniprot_canonical_ac": "P40345-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005291", "url": "https://www.yeastgenome.org/locus/S000005291" }, { "database": "iPTMnet", "id": "P40345", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40345" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40345-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005291", "url": "https://www.yeastgenome.org/locus/S000005291" }, { "database": "iPTMnet", "id": "P40345", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40345" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40345-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005291", "url": "https://www.yeastgenome.org/locus/S000005291" }, { "database": "iPTMnet", "id": "P40345", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40345" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40345-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005291", "url": "https://www.yeastgenome.org/locus/S000005291" }, { "database": "iPTMnet", "id": "P40345", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40345" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40345-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005291", "url": "https://www.yeastgenome.org/locus/S000005291" }, { "database": "iPTMnet", "id": "P40345", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40345" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40345-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Ser324", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" }, { "database": "PubMed", "id": "31422915", "url": "https://glygen.org/publication/PubMed/31422915" } ] } ] }, { "uniprot_canonical_ac": "P40345-1", "start_pos": "618", "end_pos": "618", "site_lbl": "His618", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes catalytic activity. Fails to localize to lipid droplet biogenesis sites on the ER.", "evidence": [ { "database": "UniProtKB", "id": "P40345", "url": "https://www.uniprot.org/uniprotkb/P40345" }, { "database": "PubMed", "id": "32349126", "url": "https://glygen.org/publication/PubMed/32349126" } ] } ] } ], "record_id": "P40345-1" }, { "uniprot_canonical_ac": "P40347-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40347", "url": "https://www.uniprot.org/uniprotkb/P40347" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 161, "chemical_mass": 18675.0, "gene_names": "LTP1;LTP1;YP9499.28C", "protein_name": "Low molecular weight phosphotyrosine protein phosphatase", "disease": [ { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:12995", "name": "conduct disorder", "description": "A specific developmental disorder marked by a pattern of repetitive behavior wherein the rights of others or social norms are violated.", "url": "https://disease-ontology.org/term/DOID:12995", "evidence": [ { "id": "12995", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12995" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40347", "url": "https://www.uniprot.org/uniprotkb/P40347" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40347", "url": "https://www.uniprot.org/uniprotkb/P40347" } ], "pmid": "" } ], "molecular_function": [ { "name": "acid phosphatase activity", "id": "GO:0003993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003993", "evidence": [ { "database": "UniProtKB", "id": "P40347", "url": "https://www.uniprot.org/uniprotkb/P40347" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "P40347", "url": "https://www.uniprot.org/uniprotkb/P40347" } ], "pmid": "" } ], "biological_process": [ { "name": "protein dephosphorylation", "id": "GO:0006470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006470", "evidence": [ { "database": "UniProtKB", "id": "P40347", "url": "https://www.uniprot.org/uniprotkb/P40347" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40347-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006277", "url": "https://www.yeastgenome.org/locus/S000006277" }, { "database": "iPTMnet", "id": "P40347", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40347" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40347-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40347", "url": "https://www.uniprot.org/uniprotkb/P40347" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40347", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40347" }, { "database": "SGD", "id": "S000006277", "url": "https://www.yeastgenome.org/locus/S000006277" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40347-1" }, { "uniprot_canonical_ac": "P40350-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40350", "url": "https://www.uniprot.org/uniprotkb/P40350" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 334, "chemical_mass": 38347.0, "gene_names": "ALG5;ALG5;P1437", "protein_name": "Dolichyl-phosphate beta-glucosyltransferase", "disease": [ { "disease_id": "DOID:0050570", "name": "congenital disorder of glycosylation type I", "description": "A congenital disorder of glycosylation characterized by under-glycosylated serum glycoproteins.", "url": "https://disease-ontology.org/term/DOID:0050570", "evidence": [ { "id": "0050570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050570" } ], "weight": 0.0 }, { "disease_id": "DOID:0060952", "name": "polycystic kidney disease 7", "description": "A autosomal dominant polycystic kidney disease characterized by the development of small kidney cysts and renal interstitial fibrosis causing adult-onset progressive loss of kidney function leading to end-stage kidney disease after around 60 years of age that has_material_basis_in heterozygous mutation in the ALG5 gene on chromosome 13q13.", "url": "https://disease-ontology.org/term/DOID:0060952", "evidence": [ { "id": "0060952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P40350", "url": "https://www.uniprot.org/uniprotkb/P40350" } ], "pmid": "" } ], "biological_process": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "P40350", "url": "https://www.uniprot.org/uniprotkb/P40350" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "P40350", "url": "https://www.uniprot.org/uniprotkb/P40350" } ], "pmid": "" } ], "molecular_function": [ { "name": "dolichyl-phosphate beta-glucosyltransferase activity", "id": "GO:0004581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004581", "evidence": [ { "database": "UniProtKB", "id": "P40350", "url": "https://www.uniprot.org/uniprotkb/P40350" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40350-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Ser301", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006148", "url": "https://www.yeastgenome.org/locus/S000006148" }, { "database": "iPTMnet", "id": "P40350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40350" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40350-1" }, { "uniprot_canonical_ac": "P40353-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40353", "url": "https://www.uniprot.org/uniprotkb/P40353" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 525, "chemical_mass": 61036.0, "gene_names": "ATF1;ATF1", "protein_name": "Alcohol O-acetyltransferase 1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40353", "url": "https://www.uniprot.org/uniprotkb/P40353" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P40353", "url": "https://www.uniprot.org/uniprotkb/P40353" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P40353", "url": "https://www.uniprot.org/uniprotkb/P40353" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "P40353", "url": "https://www.uniprot.org/uniprotkb/P40353" } ], "pmid": "" }, { "name": "N-acetyltransferase activity", "id": "GO:0008080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008080", "evidence": [ { "database": "UniProtKB", "id": "P40353", "url": "https://www.uniprot.org/uniprotkb/P40353" } ], "pmid": "" }, { "name": "alcohol O-acetyltransferase activity", "id": "GO:0004026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004026", "evidence": [ { "database": "UniProtKB", "id": "P40353", "url": "https://www.uniprot.org/uniprotkb/P40353" } ], "pmid": "" } ], "biological_process": [ { "name": "acetate ester metabolic process involved in fermentation", "id": "GO:1901089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901089", "evidence": [ { "database": "UniProtKB", "id": "P40353", "url": "https://www.uniprot.org/uniprotkb/P40353" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40353-1", "start_pos": "191", "end_pos": "191", "site_lbl": "His191", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Only moderately reduces the thioesterase activity.", "evidence": [ { "database": "UniProtKB", "id": "P40353", "url": "https://www.uniprot.org/uniprotkb/P40353" }, { "database": "PubMed", "id": "28160314", "url": "https://glygen.org/publication/PubMed/28160314" } ] } ] } ], "record_id": "P40353-1" }, { "uniprot_canonical_ac": "P40358-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 645, "chemical_mass": 75144.0, "gene_names": "JEM1;HRC558;J1083;JEM1;KAR8", "protein_name": "DnaJ-like chaperone JEM1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "pmid": "" }, { "name": "nuclear outer membrane-endoplasmic reticulum membrane network", "id": "GO:0042175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042175", "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "pmid": "" }, { "name": "misfolded protein binding", "id": "GO:0051787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051787", "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "pmid": "" } ], "biological_process": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "pmid": "" }, { "name": "protein folding in endoplasmic reticulum", "id": "GO:0034975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034975", "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "pmid": "" }, { "name": "karyogamy involved in conjugation with cellular fusion", "id": "GO:0000742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000742", "evidence": [ { "database": "UniProtKB", "id": "P40358", "url": "https://www.uniprot.org/uniprotkb/P40358" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40358-1" }, { "uniprot_canonical_ac": "P40359-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40359", "url": "https://www.uniprot.org/uniprotkb/P40359" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 213, "chemical_mass": 25061.0, "gene_names": "PSF2;CDC102;HRF213;J1086;PSF2", "protein_name": "DNA replication complex GINS protein PSF2", "disease": [], "cellular_component": [ { "name": "DNA replication preinitiation complex", "id": "GO:0031261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031261", "evidence": [ { "database": "UniProtKB", "id": "P40359", "url": "https://www.uniprot.org/uniprotkb/P40359" } ], "pmid": "" }, { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "P40359", "url": "https://www.uniprot.org/uniprotkb/P40359" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40359", "url": "https://www.uniprot.org/uniprotkb/P40359" } ], "pmid": "" }, { "name": "GINS complex", "id": "GO:0000811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000811", "evidence": [ { "database": "UniProtKB", "id": "P40359", "url": "https://www.uniprot.org/uniprotkb/P40359" } ], "pmid": "" }, { "name": "CMG complex", "id": "GO:0071162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071162", "evidence": [ { "database": "UniProtKB", "id": "P40359", "url": "https://www.uniprot.org/uniprotkb/P40359" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "P40359", "url": "https://www.uniprot.org/uniprotkb/P40359" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "P40359", "url": "https://www.uniprot.org/uniprotkb/P40359" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "P40359", "url": "https://www.uniprot.org/uniprotkb/P40359" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40359-1" }, { "uniprot_canonical_ac": "P40360-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40360", "url": "https://www.uniprot.org/uniprotkb/P40360" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 574, "chemical_mass": 65610.0, "gene_names": "ARG2;ARG2;HRB574;J1091", "protein_name": "Amino-acid acetyltransferase, mitochondrial", "disease": [ { "disease_id": "DOID:0112258", "name": "N-acetylglutamate synthase deficiency", "description": "A urea cycle disorder characterized by accumulation of ammonia in the blood that has_material_basis_in homozygous or compound heterozygous mutation in the NAGS gene on chromosome 17q21.31.", "url": "https://disease-ontology.org/term/DOID:0112258", "evidence": [ { "id": "0112258", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112258" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "L-glutamate N-acetyltransferase activity", "id": "GO:0004042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004042", "evidence": [ { "database": "UniProtKB", "id": "P40360", "url": "https://www.uniprot.org/uniprotkb/P40360" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P40360", "url": "https://www.uniprot.org/uniprotkb/P40360" } ], "pmid": "" } ], "biological_process": [ { "name": "L-arginine biosynthetic process", "id": "GO:0006526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006526", "evidence": [ { "database": "UniProtKB", "id": "P40360", "url": "https://www.uniprot.org/uniprotkb/P40360" } ], "pmid": "" }, { "name": "ornithine biosynthetic process", "id": "GO:0006592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006592", "evidence": [ { "database": "UniProtKB", "id": "P40360", "url": "https://www.uniprot.org/uniprotkb/P40360" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40360-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Ser312", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 312, "start_aa": "Ser", "end_pos": 312, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser312", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40360", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40360" } ] } ] }, { "uniprot_canonical_ac": "P40360-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 313, "start_aa": "Ser", "end_pos": 313, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser313", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40360", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40360" } ] } ] }, { "uniprot_canonical_ac": "P40360-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 314, "start_aa": "Ser", "end_pos": 314, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser314", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40360", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40360" } ] } ] }, { "uniprot_canonical_ac": "P40360-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40360", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40360" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P40360-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Thr29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40360", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40360" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] } ], "record_id": "P40360-1" }, { "uniprot_canonical_ac": "P40367-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40367", "url": "https://www.uniprot.org/uniprotkb/P40367" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 830, "chemical_mass": 94851.0, "gene_names": "LAS21;GPI7;HRC830;J1132;LAS21", "protein_name": "GPI ethanolamine phosphate transferase 2", "disease": [], "molecular_function": [ { "name": "CP2 mannose-ethanolamine phosphotransferase activity", "id": "GO:0051267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051267", "evidence": [ { "database": "UniProtKB", "id": "P40367", "url": "https://www.uniprot.org/uniprotkb/P40367" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40367", "url": "https://www.uniprot.org/uniprotkb/P40367" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P40367", "url": "https://www.uniprot.org/uniprotkb/P40367" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P40367", "url": "https://www.uniprot.org/uniprotkb/P40367" } ], "pmid": "" } ], "biological_process": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "P40367", "url": "https://www.uniprot.org/uniprotkb/P40367" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40367-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Asn145", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 145, "start_aa": "Asn", "end_pos": 145, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn145", "evidence": [ { "id": "P40367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40367#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40367-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Asn185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 185, "start_aa": "Asn", "end_pos": 185, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn185", "evidence": [ { "id": "P40367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40367#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40367-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Asn298", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 298, "start_aa": "Asn", "end_pos": 298, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn298", "evidence": [ { "id": "P40367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40367#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40367-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Asn506", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 506, "start_aa": "Asn", "end_pos": 506, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn506", "evidence": [ { "id": "P40367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40367#ptm_processing" } ] } ] } ], "record_id": "P40367-1" }, { "uniprot_canonical_ac": "P40414-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 161, "chemical_mass": 19093.0, "gene_names": "TPM2;TPM2", "protein_name": "Tropomyosin-2", "disease": [], "cellular_component": [ { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" }, { "name": "actomyosin contractile ring", "id": "GO:0005826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005826", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" }, { "name": "actin filament bundle", "id": "GO:0032432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032432", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" }, { "name": "cellular bud neck contractile ring", "id": "GO:0000142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000142", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" }, { "name": "mitotic actomyosin contractile ring assembly", "id": "GO:1903475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903475", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" }, { "name": "cellular bud site selection", "id": "GO:0000282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000282", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" }, { "name": "actin lateral binding", "id": "GO:0003786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003786", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40414-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001400", "url": "https://www.yeastgenome.org/locus/S000001400" }, { "database": "iPTMnet", "id": "P40414", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40414" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40414-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40414", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40414" }, { "database": "SGD", "id": "S000001400", "url": "https://www.yeastgenome.org/locus/S000001400" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40414-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40414", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40414" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001400", "url": "https://www.yeastgenome.org/locus/S000001400" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40414-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001400", "url": "https://www.yeastgenome.org/locus/S000001400" }, { "database": "iPTMnet", "id": "P40414", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40414" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40414-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40414", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40414" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001400", "url": "https://www.yeastgenome.org/locus/S000001400" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40414-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40414", "url": "https://www.uniprot.org/uniprotkb/P40414" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40414", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40414" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001400", "url": "https://www.yeastgenome.org/locus/S000001400" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40414-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001400", "url": "https://www.yeastgenome.org/locus/S000001400" }, { "database": "iPTMnet", "id": "P40414", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40414" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40414-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001400", "url": "https://www.yeastgenome.org/locus/S000001400" }, { "database": "iPTMnet", "id": "P40414", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40414" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40414-1" }, { "uniprot_canonical_ac": "P40422-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 70, "chemical_mass": 7716.0, "gene_names": "RPC10;RPB12;RPC10;YHR143BW", "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC4", "disease": [], "biological_process": [ { "name": "transcription by RNA polymerase I", "id": "GO:0006360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006360", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "tRNA transcription by RNA polymerase III", "id": "GO:0042797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042797", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase I", "id": "GO:0006362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006362", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "termination of RNA polymerase III transcription", "id": "GO:0006386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006386", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase I promoter", "id": "GO:0006361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006361", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "termination of RNA polymerase I transcription", "id": "GO:0006363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006363", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "RNA-templated transcription", "id": "GO:0001172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001172", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "nucleolar large rRNA transcription by RNA polymerase I", "id": "GO:0042790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042790", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "RNA polymerase II, core complex", "id": "GO:0005665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005665", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "RNA polymerase I complex", "id": "GO:0005736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005736", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" }, { "name": "RNA polymerase III complex", "id": "GO:0005666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005666", "evidence": [ { "database": "UniProtKB", "id": "P40422", "url": "https://www.uniprot.org/uniprotkb/P40422" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40422-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001185", "url": "https://www.yeastgenome.org/locus/S000001185" }, { "database": "iPTMnet", "id": "P40422", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40422" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40422-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40422", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40422" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001185", "url": "https://www.yeastgenome.org/locus/S000001185" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40422-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Thr26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001185", "url": "https://www.yeastgenome.org/locus/S000001185" }, { "database": "iPTMnet", "id": "P40422", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40422" }, { "database": "PubMed", "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345" } ] } ] }, { "uniprot_canonical_ac": "P40422-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001185", "url": "https://www.yeastgenome.org/locus/S000001185" }, { "database": "iPTMnet", "id": "P40422", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40422" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40422-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40422", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40422" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001185", "url": "https://www.yeastgenome.org/locus/S000001185" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40422-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001185", "url": "https://www.yeastgenome.org/locus/S000001185" }, { "database": "iPTMnet", "id": "P40422", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40422" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40422-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001185", "url": "https://www.yeastgenome.org/locus/S000001185" }, { "database": "iPTMnet", "id": "P40422", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40422" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40422-1" }, { "uniprot_canonical_ac": "P40438-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1549, "chemical_mass": 174428.0, "gene_names": "VTH1;VTH1", "protein_name": "VPS10 homolog 1", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:576", "name": "proteinuria", "description": "A kidney disease that is characterized by the presence of excess proteins in the urine.", "url": "https://disease-ontology.org/term/DOID:576", "evidence": [ { "id": "576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:576" } ], "weight": 0.0 }, { "disease_id": "DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta.", "url": "https://disease-ontology.org/term/DOID:7693", "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" }, { "name": "signal sequence binding", "id": "GO:0005048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005048", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" } ], "biological_process": [ { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "P40438", "url": "https://www.uniprot.org/uniprotkb/P40438" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40438-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Asn479", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 479, "start_aa": "Asn", "end_pos": 479, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn479", "evidence": [ { "id": "P40438", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40438#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40438-1", "start_pos": "769", "end_pos": "769", "site_lbl": "Asn769", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 769, "start_aa": "Asn", "end_pos": 769, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn769", "evidence": [ { "id": "P40438", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40438#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40438-1", "start_pos": "986", "end_pos": "986", "site_lbl": "Asn986", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 986, "start_aa": "Asn", "end_pos": 986, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn986", "evidence": [ { "id": "P40438", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40438#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40438-1", "start_pos": "1498", "end_pos": "1498", "site_lbl": "Ser1498", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001435", "url": "https://www.yeastgenome.org/locus/S000001435" }, { "database": "iPTMnet", "id": "P40438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40438" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40438-1", "start_pos": "1500", "end_pos": "1500", "site_lbl": "Ser1500", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001435", "url": "https://www.yeastgenome.org/locus/S000001435" }, { "database": "iPTMnet", "id": "P40438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40438" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40438-1", "start_pos": "1536", "end_pos": "1536", "site_lbl": "Ser1536", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001435", "url": "https://www.yeastgenome.org/locus/S000001435" }, { "database": "iPTMnet", "id": "P40438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40438" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40438-1", "start_pos": "1539", "end_pos": "1539", "site_lbl": "Ser1539", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001435", "url": "https://www.yeastgenome.org/locus/S000001435" }, { "database": "iPTMnet", "id": "P40438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40438" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40438-1", "start_pos": "500", "end_pos": "500", "site_lbl": "Ser500", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40438" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] } ], "record_id": "P40438-1" }, { "uniprot_canonical_ac": "P40462-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40462", "url": "https://www.uniprot.org/uniprotkb/P40462" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 946, "chemical_mass": 107723.0, "gene_names": "TMA108;TAE3;TMA108", "protein_name": "Protein TMA108", "disease": [ { "disease_id": "DOID:13129", "name": "severe pre-eclampsia", "description": "A pre-eclampsia that has_symptom at least one of the following: SBP of 160mm HG or higher or DPB of 110mm HG or higher on 2 occasions at least 6 hours apart, proteinuria more than 5g in a 24-hour collection, pulmonary edema or cyanosis, oliguria, persistent headaches, epigastric pain and/or impaired liver function, thrombocytopenia, oligohydramnios, decreased fetal growth or placental abruption.", "url": "https://disease-ontology.org/term/DOID:13129", "evidence": [ { "id": "13129", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13129" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 }, { "disease_id": "DOID:2893", "name": "cervix carcinoma", "description": "A cervical cancer that is located_in the cervix uteri or located_in the cervical area and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2893", "evidence": [ { "id": "2893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2893" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of cytoplasmic translation", "id": "GO:2000765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000765", "evidence": [ { "database": "UniProtKB", "id": "P40462", "url": "https://www.uniprot.org/uniprotkb/P40462" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P40462", "url": "https://www.uniprot.org/uniprotkb/P40462" } ], "pmid": "" }, { "name": "peptide catabolic process", "id": "GO:0043171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043171", "evidence": [ { "database": "UniProtKB", "id": "P40462", "url": "https://www.uniprot.org/uniprotkb/P40462" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "P40462", "url": "https://www.uniprot.org/uniprotkb/P40462" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40462", "url": "https://www.uniprot.org/uniprotkb/P40462" } ], "pmid": "" }, { "name": "nascent polypeptide-associated complex", "id": "GO:0005854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005854", "evidence": [ { "database": "UniProtKB", "id": "P40462", "url": "https://www.uniprot.org/uniprotkb/P40462" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P40462", "url": "https://www.uniprot.org/uniprotkb/P40462" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "P40462", "url": "https://www.uniprot.org/uniprotkb/P40462" } ], "pmid": "" }, { "name": "nascent polypeptide-associated complex binding", "id": "GO:1990593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990593", "evidence": [ { "database": "UniProtKB", "id": "P40462", "url": "https://www.uniprot.org/uniprotkb/P40462" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40462-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Ser460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40462", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40462" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40462-1", "start_pos": "666", "end_pos": "666", "site_lbl": "Ser666", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001399", "url": "https://www.yeastgenome.org/locus/S000001399" }, { "database": "iPTMnet", "id": "P40462", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40462" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40462-1", "start_pos": "704", "end_pos": "704", "site_lbl": "Ser704", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40462", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40462" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] } ], "record_id": "P40462-1" }, { "uniprot_canonical_ac": "P40465-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 213, "chemical_mass": 24953.0, "gene_names": "CSM2;CSM2", "protein_name": "Chromosome segregation in meiosis protein 2", "disease": [], "molecular_function": [ { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" }, { "name": "Shu complex", "id": "GO:0097196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097196", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" } ], "biological_process": [ { "name": "meiotic chromosome segregation", "id": "GO:0045132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045132", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" }, { "name": "recombinational repair", "id": "GO:0000725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000725", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" }, { "name": "DNA recombinase assembly", "id": "GO:0000730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000730", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" }, { "name": "error-free postreplication DNA repair", "id": "GO:0042275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042275", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" }, { "name": "maintenance of rDNA", "id": "GO:0043007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043007", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" }, { "name": "positive regulation of single-strand break repair via homologous recombination", "id": "GO:1903112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903112", "evidence": [ { "database": "UniProtKB", "id": "P40465", "url": "https://www.uniprot.org/uniprotkb/P40465" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40465-1" }, { "uniprot_canonical_ac": "P40466-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 484, "chemical_mass": 53490.0, "gene_names": "FKH1;FKH1", "protein_name": "Fork head protein homolog 1", "disease": [ { "disease_id": "DOID:0050328", "name": "congenital hypothyroidism", "description": "A hypothyroidism that is present at birth.", "url": "https://disease-ontology.org/term/DOID:0050328", "evidence": [ { "id": "0050328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050328" } ], "weight": 0.0 }, { "disease_id": "DOID:0050655", "name": "Bamforth-Lazarus syndrome", "description": "A hypothyroidism that is characterized by thyroid dysgenesis, cleft palate, spiky hair and bifid epiglottis, has_material_basis_in homozygous mutation in the FKHL15 gene on chromosome 9q22.", "url": "https://disease-ontology.org/term/DOID:0050655", "evidence": [ { "id": "0050655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050655" } ], "weight": 0.0 }, { "disease_id": "DOID:0060108", "name": "brain glioma", "description": "A brain cancer that has_material_basis_in glial cells.", "url": "https://disease-ontology.org/term/DOID:0060108", "evidence": [ { "id": "0060108", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060108" } ], "weight": 0.0 }, { "disease_id": "DOID:0060260", "name": "ptosis", "description": "An eye disease characterized by the drooping or falling of the upper or lower eyelid.", "url": "https://disease-ontology.org/term/DOID:0060260", "evidence": [ { "id": "0060260", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060260" } ], "weight": 0.0 }, { "disease_id": "DOID:0060648", "name": "anterior segment dysgenesis", "description": "An eye disease that is characterized by iris hypoplasia, an enlarged or reduced corneal diameter, corneal vascularization and opacity, posterior embryotoxon, corectopia, polycoria, an abnormal iridocorneal angle, ectopia lentis, and anterior synechiae between the iris and posterior corneal surface and is located_in the anterior segment of the eye.", "url": "https://disease-ontology.org/term/DOID:0060648", "evidence": [ { "id": "0060648", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060648" } ], "weight": 0.0 }, { "disease_id": "DOID:0060744", "name": "Pendred Syndrome", "description": "A syndrome characterized by bilateral prelingual sensorineural hearing loss and euthyroid goiter and that has_material_basis_in homozygous or compound heterozygous mutation in the SLC26A4 gene on chromosome 7q.", "url": "https://disease-ontology.org/term/DOID:0060744", "evidence": [ { "id": "0060744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060744" } ], "weight": 0.0 }, { "disease_id": "DOID:0060928", "name": "otosclerosis 11", "description": "An otosclerosis that is characterized by onset of progressive hearing loss in the second to third decade of life and that has_material_basis_in the locus associated with Forkhead Box L1 gene (FOXL1) on chromosome 16q24.", "url": "https://disease-ontology.org/term/DOID:0060928", "evidence": [ { "id": "0060928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060928" } ], "weight": 0.0 }, { "disease_id": "DOID:0080607", "name": "anterior segment dysgenesis 2", "description": "An anterior segment dysgenesis that has_material_basis_in homozygous, compound heterozygous, or heterozygous mutation in the FOXE3 gene on chromosome 1p33.", "url": "https://disease-ontology.org/term/DOID:0080607", "evidence": [ { "id": "0080607", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080607" } ], "weight": 0.0 }, { "disease_id": "DOID:0080608", "name": "anterior segment dysgenesis 3", "description": "An anterior segment dysgenesis that has_material_basis_in heterozygous mutation in the FOXC1 gene on chromosome 6p25.", "url": "https://disease-ontology.org/term/DOID:0080608", "evidence": [ { "id": "0080608", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080608" } ], "weight": 0.0 }, { "disease_id": "DOID:0110122", "name": "Axenfeld-Rieger syndrome type 3", "description": "An Axenfeld-Rieger characterized by an anteriorly displaced Schwalbe line, the presence of another ocular anomaly (hypoplasia of iris stroma, corectopia, or iridocorneal adhesions), and nonocular anomalies including maxillary hypoplasia, hypodontia, microdontia, protuberant periumbilical skin, sensorineural hearing loss, and congenital cardiac or renal anomalies syndrome that has_material_basis_in heterozygous mutation in the FOXC1 gene on chromosome 6p25.", "url": "https://disease-ontology.org/term/DOID:0110122", "evidence": [ { "id": "0110122", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110122" } ], "weight": 0.0 }, { "disease_id": "DOID:0110230", "name": "cataract 34 multiple types", "description": "A cataract that has_material_basis_in variation in the region 1p34.3-p32.2.", "url": "https://disease-ontology.org/term/DOID:0110230", "evidence": [ { "id": "0110230", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110230" } ], "weight": 0.0 }, { "disease_id": "DOID:0110498", "name": "autosomal recessive nonsyndromic deafness 4", "description": "An autosomal recessive nonsyndromic deafness that has_material_basis_in mutation in the SLC26A4 gene on chromosome 7q22.", "url": "https://disease-ontology.org/term/DOID:0110498", "evidence": [ { "id": "0110498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110498" } ], "weight": 0.0 }, { "disease_id": "DOID:0111509", "name": "lymphedema-distichiasis syndrome", "description": "A syndrome characterized by lymphedema of the limbs and double rows of eyelashes that has_material_basis_in heterozygous mutation in the FOXC2 gene on chromosome 16q24.1.", "url": "https://disease-ontology.org/term/DOID:0111509", "evidence": [ { "id": "0111509", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111509" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10952", "name": "nephritis", "description": "A kidney disease that is characterized by an inflammation of the kidneys.", "url": "https://disease-ontology.org/term/DOID:10952", "evidence": [ { "id": "10952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10952" } ], "weight": 0.0 }, { "disease_id": "DOID:11211", "name": "buphthalmos", "description": "A hydrophthalmos characterized by early onset glaucoma in one or both eyes with elevated intraocular pressure, increased corneal diameter, and swelling of the globe and has_symptom early vision loss, photophobia, blepharospasm, tearing, increased corneal diameter, increased corneal thickness, and enlarged globe. Buphthalmos is caused by severe congenital defects of the trabecular meshwork and anterior chamber angle that block aqueous outflow and raises intraocular pressure, leading to optic nerve atrophy and early vision loss.", "url": "https://disease-ontology.org/term/DOID:11211", "evidence": [ { "id": "11211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11211" } ], "weight": 0.0 }, { "disease_id": "DOID:11367", "name": "congenital aphakia", "description": "", "url": "https://disease-ontology.org/term/DOID:11367", "evidence": [ { "id": "11367", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11367" } ], "weight": 0.0 }, { "disease_id": "DOID:11476", "name": "osteoporosis", "description": "A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.", "url": "https://disease-ontology.org/term/DOID:11476", "evidence": [ { "id": "11476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11476" } ], "weight": 0.0 }, { "disease_id": "DOID:12185", "name": "otosclerosis", "description": "An otitis interna characterized by isolated endochondral bone sclerosis of the labyrinthine capsule.", "url": "https://disease-ontology.org/term/DOID:12185", "evidence": [ { "id": "12185", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12185" } ], "weight": 0.0 }, { "disease_id": "DOID:12306", "name": "vitiligo", "description": "An autoimmune disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes.", "url": "https://disease-ontology.org/term/DOID:12306", "evidence": [ { "id": "12306", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12306" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:14004", "name": "thoracic aortic aneurysm", "description": "An aortic aneurysm that is located_in the thoracic aorta.", "url": "https://disease-ontology.org/term/DOID:14004", "evidence": [ { "id": "14004", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14004" } ], "weight": 0.0 }, { "disease_id": "DOID:14686", "name": "Axenfeld-Rieger syndrome", "description": "An eye disease characterized by anterior segment ocular dysgenesis in addition to systemic abnormalities such as dental, cardiac, craniofacial, and abdominal wall defects.", "url": "https://disease-ontology.org/term/DOID:14686", "evidence": [ { "id": "14686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14686" } ], "weight": 0.0 }, { "disease_id": "DOID:1520", "name": "colon carcinoma", "description": "A colon cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1520", "evidence": [ { "id": "1520", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1520" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:2907", "name": "Goldenhar syndrome", "description": "A syndrome that is characterized by incomplete development of the ear, nose, soft palate, lip, and mandible. It is associated with anomalous development of the first branchial arch and second branchial arch.", "url": "https://disease-ontology.org/term/DOID:2907", "evidence": [ { "id": "2907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2907" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3905", "name": "lung carcinoma", "description": "A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.", "url": "https://disease-ontology.org/term/DOID:3905", "evidence": [ { "id": "3905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3905" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:3969", "name": "papillary thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer and arises from the follicular cells of the thyroid gland.", "url": "https://disease-ontology.org/term/DOID:3969", "evidence": [ { "id": "3969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3969" } ], "weight": 0.0 }, { "disease_id": "DOID:4914", "name": "esophagus adenocarcinoma", "description": "An esophageal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:4914", "evidence": [ { "id": "4914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4914" } ], "weight": 0.0 }, { "disease_id": "DOID:4977", "name": "lymphedema", "description": "A lymphatic system disease that is characterized by the abnormal accumulation of lymph fluid in the body's tissues, leading to swelling.", "url": "https://disease-ontology.org/term/DOID:4977", "evidence": [ { "id": "4977", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4977" } ], "weight": 0.0 }, { "disease_id": "DOID:530", "name": "eyelid disease", "description": "An adnexa disease that is located_in the eyelid.", "url": "https://disease-ontology.org/term/DOID:530", "evidence": [ { "id": "530", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:530" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "centromeric DNA binding", "id": "GO:0019237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019237", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "negative regulation of transcription elongation by RNA polymerase II", "id": "GO:0034244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034244", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription", "id": "GO:0006369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006369", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated DNA replication initiation", "id": "GO:0032298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032298", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "positive regulation of silent mating-type cassette heterochromatin formation", "id": "GO:0090055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090055", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "positive regulation of DNA replication initiation", "id": "GO:1903468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903468", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "donor selection", "id": "GO:0007535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007535", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "negative regulation of pseudohyphal growth", "id": "GO:2000221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000221", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40466-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001393", "url": "https://www.yeastgenome.org/locus/S000001393" }, { "database": "iPTMnet", "id": "P40466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40466" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40466-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001393", "url": "https://www.yeastgenome.org/locus/S000001393" }, { "database": "iPTMnet", "id": "P40466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40466" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40466-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Tyr301", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001393", "url": "https://www.yeastgenome.org/locus/S000001393" }, { "database": "iPTMnet", "id": "P40466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40466" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40466-1", "start_pos": "446", "end_pos": "446", "site_lbl": "Ser446", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001393", "url": "https://www.yeastgenome.org/locus/S000001393" }, { "database": "iPTMnet", "id": "P40466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40466" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40466-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001393", "url": "https://www.yeastgenome.org/locus/S000001393" }, { "database": "iPTMnet", "id": "P40466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40466" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40466-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to reduced colony size when FKH2 is deleted.", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] }, { "uniprot_canonical_ac": "P40466-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Arg111", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Leads to reduced colony size when FKH2 is deleted.", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] }, { "uniprot_canonical_ac": "P40466-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Arg80", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Leads to reduced colony size when FKH2 is deleted.", "evidence": [ { "database": "UniProtKB", "id": "P40466", "url": "https://www.uniprot.org/uniprotkb/P40466" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] } ], "record_id": "P40466-1" }, { "uniprot_canonical_ac": "P40469-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40469", "url": "https://www.uniprot.org/uniprotkb/P40469" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1032, "chemical_mass": 117883.0, "gene_names": "MET18;MET18;MMS19", "protein_name": "DNA repair/transcription protein MET18/MMS19", "disease": [], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "P40469", "url": "https://www.uniprot.org/uniprotkb/P40469" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P40469", "url": "https://www.uniprot.org/uniprotkb/P40469" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P40469", "url": "https://www.uniprot.org/uniprotkb/P40469" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "P40469", "url": "https://www.uniprot.org/uniprotkb/P40469" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic [4Fe-4S] assembly targeting complex", "id": "GO:0097361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097361", "evidence": [ { "database": "UniProtKB", "id": "P40469", "url": "https://www.uniprot.org/uniprotkb/P40469" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40469", "url": "https://www.uniprot.org/uniprotkb/P40469" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40469", "url": "https://www.uniprot.org/uniprotkb/P40469" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40469", "url": "https://www.uniprot.org/uniprotkb/P40469" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40469-1", "start_pos": "448", "end_pos": "448", "site_lbl": "Ser448", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40469", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40469" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] } ], "record_id": "P40469-1" }, { "uniprot_canonical_ac": "P40471-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 297, "chemical_mass": 32814.0, "gene_names": "AYR1;AYR1;GBG1", "protein_name": "NADPH-dependent 1-acyldihydroxyacetone phosphate reductase", "disease": [ { "disease_id": "DOID:0080257", "name": "autosomal recessive congenital ichthyosis 13", "description": "An autosomal recessive congenital ichthyosis that is characterized by lamellar ichthyosis, ectropion, eclabium and hyperkeratosis that has_material_basis_in homozygous mutation in the SDR9C7 gene on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0080257", "evidence": [ { "id": "0080257", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080257" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidic acid biosynthetic process", "id": "GO:0006654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006654", "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" } ], "pmid": "" }, { "name": "triglyceride catabolic process", "id": "GO:0019433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019433", "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" } ], "pmid": "" } ], "molecular_function": [ { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" } ], "pmid": "" }, { "name": "acylglycerone-phosphate reductase (NADP+) activity", "id": "GO:0000140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000140", "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40471-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Ser243", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40471", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40471" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001386", "url": "https://www.yeastgenome.org/locus/S000001386" } ] } ] }, { "uniprot_canonical_ac": "P40471-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001386", "url": "https://www.yeastgenome.org/locus/S000001386" }, { "database": "iPTMnet", "id": "P40471", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40471" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40471-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001386", "url": "https://www.yeastgenome.org/locus/S000001386" }, { "database": "iPTMnet", "id": "P40471", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40471" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40471-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Completely abolishes lipase activity.", "evidence": [ { "database": "UniProtKB", "id": "P40471", "url": "https://www.uniprot.org/uniprotkb/P40471" }, { "database": "PubMed", "id": "24187129", "url": "https://glygen.org/publication/PubMed/24187129" } ] } ] } ], "record_id": "P40471-1" }, { "uniprot_canonical_ac": "P40472-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40472", "url": "https://www.uniprot.org/uniprotkb/P40472" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 476, "chemical_mass": 48190.0, "gene_names": "SIM1;PBP3;SIM1", "protein_name": "Probable secreted beta-glucosidase SIM1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40472", "url": "https://www.uniprot.org/uniprotkb/P40472" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "P40472", "url": "https://www.uniprot.org/uniprotkb/P40472" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P40472", "url": "https://www.uniprot.org/uniprotkb/P40472" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity, acting on glycosyl bonds", "id": "GO:0016798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016798", "evidence": [ { "database": "UniProtKB", "id": "P40472", "url": "https://www.uniprot.org/uniprotkb/P40472" } ], "pmid": "" } ], "biological_process": [ { "name": "polysaccharide catabolic process", "id": "GO:0000272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000272", "evidence": [ { "database": "UniProtKB", "id": "P40472", "url": "https://www.uniprot.org/uniprotkb/P40472" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P40472", "url": "https://www.uniprot.org/uniprotkb/P40472" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40472-1", "start_pos": "423", "end_pos": "423", "site_lbl": "Asn423", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 423, "start_aa": "Asn", "end_pos": 423, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn423", "evidence": [ { "id": "P40472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40472#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40472-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 56, "start_aa": "Thr", "end_pos": 56, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr56", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] } ], "record_id": "P40472-1" }, { "uniprot_canonical_ac": "P40477-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1460, "chemical_mass": 158908.0, "gene_names": "NUP159;NUP158;NUP159;RAT7", "protein_name": "Nucleoporin NUP159", "disease": [], "biological_process": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "NLS-bearing protein import into nucleus", "id": "GO:0006607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006607", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "ribosomal small subunit export from nucleus", "id": "GO:0000056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000056", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "nuclear pore localization", "id": "GO:0051664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051664", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "nuclear pore cytoplasmic filaments", "id": "GO:0044614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044614", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "nuclear pore central transport channel", "id": "GO:0044613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044613", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "adenyl-nucleotide exchange factor activity", "id": "GO:0000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000774", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" }, { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40477-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Ser431", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 431, "start_aa": "Ser", "end_pos": 431, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser431", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Thr436", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 436, "start_aa": "Thr", "end_pos": 436, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr436", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "437", "end_pos": "437", "site_lbl": "Ser437", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 437, "start_aa": "Ser", "end_pos": 437, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser437", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Ser441", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 441, "start_aa": "Ser", "end_pos": 441, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser441", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "448", "end_pos": "448", "site_lbl": "Thr448", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 448, "start_aa": "Thr", "end_pos": 448, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr448", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Ser455", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 455, "start_aa": "Ser", "end_pos": 455, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser455", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Ser458", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 458, "start_aa": "Ser", "end_pos": 458, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser458", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Ser460", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 460, "start_aa": "Ser", "end_pos": 460, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser460", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Ser461", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 461, "start_aa": "Ser", "end_pos": 461, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser461", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "462", "end_pos": "462", "site_lbl": "Ser462", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 462, "start_aa": "Ser", "end_pos": 462, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser462", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Ser468", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 468, "start_aa": "Ser", "end_pos": 468, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser468", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Ser471", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 471, "start_aa": "Ser", "end_pos": 471, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser471", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Ser472", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 472, "start_aa": "Ser", "end_pos": 472, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser472", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "557", "end_pos": "557", "site_lbl": "Thr557", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 557, "start_aa": "Thr", "end_pos": 557, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr557", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "583", "end_pos": "583", "site_lbl": "Thr583", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 583, "start_aa": "Thr", "end_pos": 583, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr583", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "721", "end_pos": "721", "site_lbl": "Ser721", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 721, "start_aa": "Ser", "end_pos": 721, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser721", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "724", "end_pos": "724", "site_lbl": "Ser724", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 724, "start_aa": "Ser", "end_pos": 724, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser724", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "726", "end_pos": "726", "site_lbl": "Thr726", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 726, "start_aa": "Thr", "end_pos": 726, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr726", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "727", "end_pos": "727", "site_lbl": "Thr727", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 727, "start_aa": "Thr", "end_pos": 727, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr727", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "732", "end_pos": "732", "site_lbl": "Thr732", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 732, "start_aa": "Thr", "end_pos": 732, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr732", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "735", "end_pos": "735", "site_lbl": "Ser735", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 735, "start_aa": "Ser", "end_pos": 735, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser735", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "738", "end_pos": "738", "site_lbl": "Ser738", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 738, "start_aa": "Ser", "end_pos": 738, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser738", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "739", "end_pos": "739", "site_lbl": "Ser739", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 739, "start_aa": "Ser", "end_pos": 739, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser739", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "949", "end_pos": "949", "site_lbl": "Ser949", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 949, "start_aa": "Ser", "end_pos": 949, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser949", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "951", "end_pos": "951", "site_lbl": "Ser951", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 951, "start_aa": "Ser", "end_pos": 951, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser951", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40477", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40477" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "1041", "end_pos": "1041", "site_lbl": "Ser1041", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "1042", "end_pos": "1042", "site_lbl": "Ser1042", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "1047", "end_pos": "1047", "site_lbl": "Ser1047", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "1065", "end_pos": "1065", "site_lbl": "Ser1065", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "1068", "end_pos": "1068", "site_lbl": "Ser1068", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "1209", "end_pos": "1209", "site_lbl": "Ser1209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "1307", "end_pos": "1307", "site_lbl": "Thr1307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "1420", "end_pos": "1420", "site_lbl": "Ser1420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "1426", "end_pos": "1426", "site_lbl": "Ser1426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "1428", "end_pos": "1428", "site_lbl": "Thr1428", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Ser402", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Thr406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "533", "end_pos": "533", "site_lbl": "Ser533", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "543", "end_pos": "543", "site_lbl": "Ser543", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "654", "end_pos": "654", "site_lbl": "Thr654", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "657", "end_pos": "657", "site_lbl": "Ser657", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "674", "end_pos": "674", "site_lbl": "Ser674", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "678", "end_pos": "678", "site_lbl": "Ser678", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "680", "end_pos": "680", "site_lbl": "Ser680", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "709", "end_pos": "709", "site_lbl": "Ser709", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "710", "end_pos": "710", "site_lbl": "Ser710", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "745", "end_pos": "745", "site_lbl": "Ser745", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "748", "end_pos": "748", "site_lbl": "Ser748", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "749", "end_pos": "749", "site_lbl": "Ser749", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "751", "end_pos": "751", "site_lbl": "Thr751", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "755", "end_pos": "755", "site_lbl": "Thr755", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "759", "end_pos": "759", "site_lbl": "Ser759", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "765", "end_pos": "765", "site_lbl": "Thr765", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "777", "end_pos": "777", "site_lbl": "Ser777", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "783", "end_pos": "783", "site_lbl": "Ser783", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "803", "end_pos": "803", "site_lbl": "Thr803", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "805", "end_pos": "805", "site_lbl": "Ser805", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "819", "end_pos": "819", "site_lbl": "Ser819", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "852", "end_pos": "852", "site_lbl": "Ser852", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "854", "end_pos": "854", "site_lbl": "Ser854", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "883", "end_pos": "883", "site_lbl": "Ser883", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "885", "end_pos": "885", "site_lbl": "Thr885", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "886", "end_pos": "886", "site_lbl": "Ser886", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "887", "end_pos": "887", "site_lbl": "Thr887", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "889", "end_pos": "889", "site_lbl": "Ser889", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "22213798", "url": "https://glygen.org/publication/PubMed/22213798" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "938", "end_pos": "938", "site_lbl": "Tyr938", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "940", "end_pos": "940", "site_lbl": "Ser940", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40477", "url": "https://www.uniprot.org/uniprotkb/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "942", "end_pos": "942", "site_lbl": "Ser942", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "945", "end_pos": "945", "site_lbl": "Ser945", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "948", "end_pos": "948", "site_lbl": "Thr948", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40477-1", "start_pos": "956", "end_pos": "956", "site_lbl": "Thr956", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001377", "url": "https://www.yeastgenome.org/locus/S000001377" }, { "database": "iPTMnet", "id": "P40477", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40477" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40477-1" }, { "uniprot_canonical_ac": "P40479-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40479", "url": "https://www.uniprot.org/uniprotkb/P40479" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 209, "chemical_mass": 23886.0, "gene_names": "SDP1;SDP1", "protein_name": "Dual-specificity protein phosphatase SDP1", "disease": [ { "disease_id": "DOID:0060404", "name": "chromosome 17q12 deletion syndrome", "description": "A chromosomal deletion syndrome that has_material_basis_in a chromosome 17q12 deletion and that is characterized by renal cystic disease, maturity onset diabetes of the young type 5, cognitive impairment, developmental delay (particularly of speech), autistic traits and autism spectrum disorder.", "url": "https://disease-ontology.org/term/DOID:0060404", "evidence": [ { "id": "0060404", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060404" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40479", "url": "https://www.uniprot.org/uniprotkb/P40479" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40479", "url": "https://www.uniprot.org/uniprotkb/P40479" } ], "pmid": "" } ], "molecular_function": [ { "name": "MAP kinase tyrosine/serine/threonine phosphatase activity", "id": "GO:0017017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017017", "evidence": [ { "database": "UniProtKB", "id": "P40479", "url": "https://www.uniprot.org/uniprotkb/P40479" } ], "pmid": "" }, { "name": "protein tyrosine/threonine phosphatase activity", "id": "GO:0008330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008330", "evidence": [ { "database": "UniProtKB", "id": "P40479", "url": "https://www.uniprot.org/uniprotkb/P40479" } ], "pmid": "" }, { "name": "MAP kinase tyrosine phosphatase activity", "id": "GO:0033550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033550", "evidence": [ { "database": "UniProtKB", "id": "P40479", "url": "https://www.uniprot.org/uniprotkb/P40479" } ], "pmid": "" } ], "biological_process": [ { "name": "cell integrity MAPK cascade", "id": "GO:0000196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000196", "evidence": [ { "database": "UniProtKB", "id": "P40479", "url": "https://www.uniprot.org/uniprotkb/P40479" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40479-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001375", "url": "https://www.yeastgenome.org/locus/S000001375" }, { "database": "iPTMnet", "id": "P40479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40479" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40479-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40479" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001375", "url": "https://www.yeastgenome.org/locus/S000001375" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40479-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001375", "url": "https://www.yeastgenome.org/locus/S000001375" }, { "database": "iPTMnet", "id": "P40479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40479" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40479-1" }, { "uniprot_canonical_ac": "P40480-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1083, "chemical_mass": 123556.0, "gene_names": "HOS4;HOS4", "protein_name": "Protein HOS4", "disease": [ { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:4676", "name": "uremia", "description": "", "url": "https://disease-ontology.org/term/DOID:4676", "evidence": [ { "id": "4676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4676" } ], "weight": 0.0 }, { "disease_id": "DOID:576", "name": "proteinuria", "description": "A kidney disease that is characterized by the presence of excess proteins in the urine.", "url": "https://disease-ontology.org/term/DOID:576", "evidence": [ { "id": "576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:576" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" } ], "pmid": "" }, { "name": "Set3 complex", "id": "GO:0034967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034967", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" } ], "pmid": "" }, { "name": "negative regulation of meiotic nuclear division", "id": "GO:0045835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045835", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40480-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Ser131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Ser132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Thr191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Thr192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Ser255", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Ser260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Ser268", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Ser274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Ser275", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Thr280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Ser289", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Ser290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Ser328", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Thr37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "443", "end_pos": "443", "site_lbl": "Ser443", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Ser507", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "512", "end_pos": "512", "site_lbl": "Ser512", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Thr52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Ser54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "688", "end_pos": "688", "site_lbl": "Thr688", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "690", "end_pos": "690", "site_lbl": "Ser690", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "698", "end_pos": "698", "site_lbl": "Ser698", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "700", "end_pos": "700", "site_lbl": "Thr700", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "770", "end_pos": "770", "site_lbl": "Ser770", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "773", "end_pos": "773", "site_lbl": "Ser773", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "778", "end_pos": "778", "site_lbl": "Ser778", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40480", "url": "https://www.uniprot.org/uniprotkb/P40480" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40480-1", "start_pos": "784", "end_pos": "784", "site_lbl": "Ser784", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001374", "url": "https://www.yeastgenome.org/locus/S000001374" }, { "database": "iPTMnet", "id": "P40480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40480" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40480-1" }, { "uniprot_canonical_ac": "P40485-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 686, "chemical_mass": 77995.0, "gene_names": "SLM1;LIT2;SLM1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "sphingolipid binding", "id": "GO:0046625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046625", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" } ], "biological_process": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "sphingolipid metabolic process", "id": "GO:0006665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006665", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "TOR signaling", "id": "GO:0031929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031929", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "establishment or maintenance of actin cytoskeleton polarity", "id": "GO:0030950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030950", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" }, { "name": "eisosome assembly", "id": "GO:0070941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070941", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40485-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Thr147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Thr149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Ser150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Ser346", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "530", "end_pos": "530", "site_lbl": "Ser530", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "532", "end_pos": "532", "site_lbl": "Ser532", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "533", "end_pos": "533", "site_lbl": "Ser533", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "536", "end_pos": "536", "site_lbl": "Ser536", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Ser539", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "600", "end_pos": "600", "site_lbl": "Ser600", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "611", "end_pos": "611", "site_lbl": "Thr611", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "612", "end_pos": "612", "site_lbl": "Ser612", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "638", "end_pos": "638", "site_lbl": "Tyr638", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "641", "end_pos": "641", "site_lbl": "Ser641", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "644", "end_pos": "644", "site_lbl": "Thr644", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "658", "end_pos": "658", "site_lbl": "Ser658", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "659", "end_pos": "659", "site_lbl": "Ser659", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "Q03407-1", "kinase_gene_name": "PKH1", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "17101780", "url": "https://glygen.org/publication/PubMed/17101780" } ] }, { "kinase_uniprot_canonical_ac": "Q12236-1", "kinase_gene_name": "PKH2", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "17101780", "url": "https://glygen.org/publication/PubMed/17101780" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "17101780", "url": "https://glygen.org/publication/PubMed/17101780" }, { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "686", "end_pos": "686", "site_lbl": "Ser686", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001367", "url": "https://www.yeastgenome.org/locus/S000001367" }, { "database": "iPTMnet", "id": "P40485", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40485" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Lys483", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In SLM1-PHM1; reduces phosphoinositide binding by 80% and causes mislocalization to the cytoplasm; when associated with A-487.", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" }, { "database": "PubMed", "id": "15689497", "url": "https://glygen.org/publication/PubMed/15689497" }, { "database": "PubMed", "id": "15372071", "url": "https://glygen.org/publication/PubMed/15372071" } ] } ] }, { "uniprot_canonical_ac": "P40485-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Lys487", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In SLM1-PHM1; reduces phosphoinositide binding by 80% and causes mislocalization to the cytoplasm; when associated with A-483. In SLM1-PHM2; reduces phosphoinositide binding by 95%; when associated with 477-AA-478.", "evidence": [ { "database": "UniProtKB", "id": "P40485", "url": "https://www.uniprot.org/uniprotkb/P40485" }, { "database": "PubMed", "id": "15689497", "url": "https://glygen.org/publication/PubMed/15689497" }, { "database": "PubMed", "id": "15372071", "url": "https://glygen.org/publication/PubMed/15372071" } ] } ] } ], "record_id": "P40485-1" }, { "uniprot_canonical_ac": "P40495-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40495", "url": "https://www.uniprot.org/uniprotkb/P40495" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 371, "chemical_mass": 40069.0, "gene_names": "LYS12;LYS10;LYS11;LYS12;YI9910.02C", "protein_name": "Homoisocitrate dehydrogenase, mitochondrial", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P40495", "url": "https://www.uniprot.org/uniprotkb/P40495" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "P40495", "url": "https://www.uniprot.org/uniprotkb/P40495" } ], "pmid": "" }, { "name": "homoisocitrate dehydrogenase activity", "id": "GO:0047046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047046", "evidence": [ { "database": "UniProtKB", "id": "P40495", "url": "https://www.uniprot.org/uniprotkb/P40495" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40495", "url": "https://www.uniprot.org/uniprotkb/P40495" } ], "pmid": "" } ], "biological_process": [ { "name": "lysine biosynthetic process via aminoadipic acid", "id": "GO:0019878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019878", "evidence": [ { "database": "UniProtKB", "id": "P40495", "url": "https://www.uniprot.org/uniprotkb/P40495" } ], "pmid": "" }, { "name": "lysine biosynthetic process", "id": "GO:0009085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009085", "evidence": [ { "database": "UniProtKB", "id": "P40495", "url": "https://www.uniprot.org/uniprotkb/P40495" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40495-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Thr100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Thr146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Ser207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Ser348", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Thr351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40495", "url": "https://www.uniprot.org/uniprotkb/P40495" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40495" }, { "database": "SGD", "id": "S000001356", "url": "https://www.yeastgenome.org/locus/S000001356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Tyr150", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Strongly reduced enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P40495", "url": "https://www.uniprot.org/uniprotkb/P40495" }, { "database": "PubMed", "id": "19530703", "url": "https://glygen.org/publication/PubMed/19530703" } ] } ] }, { "uniprot_canonical_ac": "P40495-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Lys206", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "M", "comment": "Strongly reduced enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P40495", "url": "https://www.uniprot.org/uniprotkb/P40495" }, { "database": "PubMed", "id": "19530703", "url": "https://glygen.org/publication/PubMed/19530703" } ] } ] } ], "record_id": "P40495-1" }, { "uniprot_canonical_ac": "P40501-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 490, "chemical_mass": 53737.0, "gene_names": "AVT7;AVT7", "protein_name": "Vacuolar amino acid transporter 7", "disease": [ { "disease_id": "DOID:0070531", "name": "foveal hypoplasia 2", "description": "A retinal disease characterized by foveal hypoplasia with decreased visual acuity and nystagmus that has_material_basis_in homozygous or compound heterozygous mutation in the SLC38A8 gene on chromosome 16q23.3. Optic nerve decussation defects and anterior segment dysgenesis are also frequently seen.", "url": "https://disease-ontology.org/term/DOID:0070531", "evidence": [ { "id": "0070531", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070531" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "regulation of sporulation", "id": "GO:0043937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043937", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" } ], "molecular_function": [ { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "L-serine transmembrane transporter activity", "id": "GO:0015194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015194", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "L-lysine transmembrane transporter activity", "id": "GO:0015189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015189", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "L-histidine transmembrane transporter activity", "id": "GO:0005290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005290", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "L-tyrosine transmembrane transporter activity", "id": "GO:0005302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005302", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transporter activity", "id": "GO:0005313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005313", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" }, { "name": "L-arginine transmembrane transporter activity", "id": "GO:0061459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061459", "evidence": [ { "database": "UniProtKB", "id": "P40501", "url": "https://www.uniprot.org/uniprotkb/P40501" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40501-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Ser316", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001350", "url": "https://www.yeastgenome.org/locus/S000001350" }, { "database": "iPTMnet", "id": "P40501", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40501" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40501-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Ser322", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001350", "url": "https://www.yeastgenome.org/locus/S000001350" }, { "database": "iPTMnet", "id": "P40501", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40501" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40501-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Ser328", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001350", "url": "https://www.yeastgenome.org/locus/S000001350" }, { "database": "iPTMnet", "id": "P40501", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40501" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40501-1", "start_pos": "345", "end_pos": "345", "site_lbl": "Ser345", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001350", "url": "https://www.yeastgenome.org/locus/S000001350" }, { "database": "iPTMnet", "id": "P40501", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40501" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40501-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001350", "url": "https://www.yeastgenome.org/locus/S000001350" }, { "database": "iPTMnet", "id": "P40501", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40501" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40501-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001350", "url": "https://www.yeastgenome.org/locus/S000001350" }, { "database": "iPTMnet", "id": "P40501", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40501" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40501-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Thr375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001350", "url": "https://www.yeastgenome.org/locus/S000001350" }, { "database": "iPTMnet", "id": "P40501", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40501" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P40501-1" }, { "uniprot_canonical_ac": "P40505-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 327, "chemical_mass": 37625.0, "gene_names": "SDS3;SDS3", "protein_name": "Transcriptional regulatory protein SDS3", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "negative regulation of rDNA heterochromatin formation", "id": "GO:0061188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061188", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "cell adhesion involved in single-species biofilm formation", "id": "GO:0043709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043709", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "negative regulation of silent mating-type cassette heterochromatin formation", "id": "GO:0061186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061186", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "regulation of invasive growth in response to glucose limitation", "id": "GO:2000217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000217", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "Rpd3L-Expanded complex", "id": "GO:0070210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070210", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" }, { "name": "Rpd3L complex", "id": "GO:0033698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033698", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40505-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Thr156", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 156, "start_aa": "Thr", "end_pos": 156, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr156", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40505", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40505" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Ser162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Thr175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Thr181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40505", "url": "https://www.uniprot.org/uniprotkb/P40505" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Thr215", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40505-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001346", "url": "https://www.yeastgenome.org/locus/S000001346" }, { "database": "iPTMnet", "id": "P40505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40505" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40505-1" }, { "uniprot_canonical_ac": "P40507-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 360, "chemical_mass": 41631.0, "gene_names": "AIR1;AIR1", "protein_name": "Protein AIR1", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" }, { "name": "TRAMP complex", "id": "GO:0031499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031499", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snoRNA catabolic process", "id": "GO:0071036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071036", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snRNA catabolic process", "id": "GO:0071037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071037", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent CUT catabolic process", "id": "GO:0071039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071039", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" }, { "name": "nuclear mRNA surveillance of mRNA 3'-end processing", "id": "GO:0071031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071031", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" }, { "name": "polyadenylation-dependent RNA catabolic process", "id": "GO:0043633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043633", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" }, { "name": "RNA fragment catabolic process", "id": "GO:0000292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000292", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40507-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Thr20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40507", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40507" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001341", "url": "https://www.yeastgenome.org/locus/S000001341" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40507-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Thr21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40507", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40507" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001341", "url": "https://www.yeastgenome.org/locus/S000001341" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40507-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Thr23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001341", "url": "https://www.yeastgenome.org/locus/S000001341" }, { "database": "iPTMnet", "id": "P40507", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40507" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40507-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001341", "url": "https://www.yeastgenome.org/locus/S000001341" }, { "database": "iPTMnet", "id": "P40507", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40507" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40507-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Ser272", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40507", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40507" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P40507-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Thr273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40507", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40507" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P40507-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001341", "url": "https://www.yeastgenome.org/locus/S000001341" }, { "database": "iPTMnet", "id": "P40507", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40507" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40507-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40507", "url": "https://www.uniprot.org/uniprotkb/P40507" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40507", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40507" }, { "database": "SGD", "id": "S000001341", "url": "https://www.yeastgenome.org/locus/S000001341" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40507-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001341", "url": "https://www.yeastgenome.org/locus/S000001341" }, { "database": "iPTMnet", "id": "P40507", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40507" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40507-1" }, { "uniprot_canonical_ac": "P40509-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 296, "chemical_mass": 33829.0, "gene_names": "SEC28;ANU2;SEC28", "protein_name": "Coatomer subunit epsilon", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "pmid": "" }, { "name": "vesicle coating", "id": "GO:0006901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006901", "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "P40509", "url": "https://www.uniprot.org/uniprotkb/P40509" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40509-1" }, { "uniprot_canonical_ac": "P40510-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 469, "chemical_mass": 51188.0, "gene_names": "SER33;SER33", "protein_name": "D-3-phosphoglycerate dehydrogenase 2", "disease": [ { "disease_id": "DOID:0050722", "name": "PHGDH deficiency", "description": "A serine deficiency that has_material_basis_in deficiency of phosphoglycerate dehydrogenase which results in a disruption of L-serine biosynthesis.", "url": "https://disease-ontology.org/term/DOID:0050722", "evidence": [ { "id": "0050722", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050722" } ], "weight": 0.0 }, { "disease_id": "DOID:0080076", "name": "Neu-Laxova syndrome 1", "description": "A serine deficiency that is characterized by multiple fatal malformations including ichthyosis, microcephaly, central nervous system abnormalities, limb deformities, intrauterine growth restriction, proptosis, anasarca, and micrognathia, and has_material_basis_in autosomal recessive inheritance of mutation in the PHGDH gene on chromosome 1p12, causing issues producing the amino acid serine.", "url": "https://disease-ontology.org/term/DOID:0080076", "evidence": [ { "id": "0080076", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080076" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" } ], "pmid": "" }, { "name": "alcohol metabolic process", "id": "GO:0006066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006066", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" } ], "pmid": "" }, { "name": "L-serine biosynthetic process", "id": "GO:0006564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006564", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" } ], "pmid": "" }, { "name": "phosphoglycerate dehydrogenase activity", "id": "GO:0004617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004617", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" } ], "pmid": "" }, { "name": "(S)-2-hydroxyglutarate dehydrogenase activity", "id": "GO:0047545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047545", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40510-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Thr31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40510", "url": "https://www.uniprot.org/uniprotkb/P40510" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Ser389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Thr45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40510-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001336", "url": "https://www.yeastgenome.org/locus/S000001336" }, { "database": "iPTMnet", "id": "P40510", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40510" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40510-1" }, { "uniprot_canonical_ac": "P40517-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40517", "url": "https://www.uniprot.org/uniprotkb/P40517" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 327, "chemical_mass": 36054.0, "gene_names": "YRB2;YRB2", "protein_name": "Ran-specific GTPase-activating protein 2", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "P40517", "url": "https://www.uniprot.org/uniprotkb/P40517" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40517", "url": "https://www.uniprot.org/uniprotkb/P40517" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P40517", "url": "https://www.uniprot.org/uniprotkb/P40517" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40517", "url": "https://www.uniprot.org/uniprotkb/P40517" } ], "pmid": "" } ], "biological_process": [ { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "P40517", "url": "https://www.uniprot.org/uniprotkb/P40517" } ], "pmid": "" }, { "name": "ribosomal small subunit export from nucleus", "id": "GO:0000056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000056", "evidence": [ { "database": "UniProtKB", "id": "P40517", "url": "https://www.uniprot.org/uniprotkb/P40517" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40517-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Thr117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Thr123", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Thr126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Ser128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Ser132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Ser163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Ser165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Thr170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40517", "url": "https://www.uniprot.org/uniprotkb/P40517" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Ser207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40517-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Thr31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40517", "url": "https://www.uniprot.org/uniprotkb/P40517" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40517" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001325", "url": "https://www.yeastgenome.org/locus/S000001325" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40517-1" }, { "uniprot_canonical_ac": "P40526-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40526", "url": "https://www.uniprot.org/uniprotkb/P40526" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 253, "chemical_mass": 30306.0, "gene_names": "DFG10;DFG10", "protein_name": "Polyprenal reductase", "disease": [ { "disease_id": "DOID:0050570", "name": "congenital disorder of glycosylation type I", "description": "A congenital disorder of glycosylation characterized by under-glycosylated serum glycoproteins.", "url": "https://disease-ontology.org/term/DOID:0050570", "evidence": [ { "id": "0050570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050570" } ], "weight": 0.0 }, { "disease_id": "DOID:0050807", "name": "Kahrizi syndrome", "description": "A syndrome that is characterized by mental retardation, cataracts, coloboma, kyphosis, and coarse facial features and has_material_basis_in mutation in the SRD5A3 gene.", "url": "https://disease-ontology.org/term/DOID:0050807", "evidence": [ { "id": "0050807", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050807" } ], "weight": 0.0 }, { "disease_id": "DOID:0080568", "name": "congenital disorder of glycosylation Iq", "description": "A congenital disorder of glycosylation I that is characterized by a highly variable phenotype typically presenting with severe visual impairment, variable ocular anomalies (such as optic nerve hypoplasia/atrophy, iris and optic nerve coloboma, congenital cataract, glaucoma), intellectual disability, cerebellar abnormalities, nystagmus, hypotonia, ataxia, and/or ichthyosiform skin lesions and has_material_basis_in homozygous or compound heterozygous mutation in the SRD5A3 gene on chromosome 4q12.", "url": "https://disease-ontology.org/term/DOID:0080568", "evidence": [ { "id": "0080568", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080568" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40526", "url": "https://www.uniprot.org/uniprotkb/P40526" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P40526", "url": "https://www.uniprot.org/uniprotkb/P40526" } ], "pmid": "" } ], "biological_process": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "P40526", "url": "https://www.uniprot.org/uniprotkb/P40526" } ], "pmid": "" }, { "name": "dolichyl monophosphate biosynthetic process", "id": "GO:0043048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043048", "evidence": [ { "database": "UniProtKB", "id": "P40526", "url": "https://www.uniprot.org/uniprotkb/P40526" } ], "pmid": "" }, { "name": "pseudohyphal growth", "id": "GO:0007124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007124", "evidence": [ { "database": "UniProtKB", "id": "P40526", "url": "https://www.uniprot.org/uniprotkb/P40526" } ], "pmid": "" } ], "molecular_function": [ { "name": "3-oxo-5-alpha-steroid 4-dehydrogenase activity", "id": "GO:0003865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003865", "evidence": [ { "database": "UniProtKB", "id": "P40526", "url": "https://www.uniprot.org/uniprotkb/P40526" } ], "pmid": "" }, { "name": "polyprenal reductase activity", "id": "GO:0160198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160198", "evidence": [ { "database": "UniProtKB", "id": "P40526", "url": "https://www.uniprot.org/uniprotkb/P40526" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40526-1" }, { "uniprot_canonical_ac": "P40527-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1151, "chemical_mass": 130218.0, "gene_names": "NEO1;NEO1", "protein_name": "Phospholipid-transporting ATPase NEO1", "disease": [ { "disease_id": "DOID:0081444", "name": "neurodevelopmental disorder with poor growth and behavioral abnormalities", "description": "An autosomal recessive intellectual developmental disorder that is characterized by global developmental delay, moderately to severely impaired intellectual development, often with absent speech, and behavioral abnormalities, including hyperactivity, short attention span, and ADHD and that has_material_basis_in homozygous or compound heterozygous mutation in the ATP9A gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0081444", "evidence": [ { "id": "0081444", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081444" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "phosphatidylethanolamine flippase activity", "id": "GO:0090555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090555", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "phosphatidylserine floppase activity", "id": "GO:0090556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090556", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "ATPase-coupled intramembrane lipid transporter activity", "id": "GO:0140326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140326", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "phosphatidylserine flippase activity", "id": "GO:0140346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140346", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "lysophosphatidylserine flippase activity", "id": "GO:0180013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180013", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "vacuole organization", "id": "GO:0007033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007033", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" }, { "name": "trans-Golgi network membrane organization", "id": "GO:0098629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098629", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40527-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "1150", "end_pos": "1150", "site_lbl": "Thr1150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "547", "end_pos": "547", "site_lbl": "Ser547", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Ser551", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Thr69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Ser81", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Ser83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Ser88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Thr90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001310", "url": "https://www.yeastgenome.org/locus/S000001310" }, { "database": "iPTMnet", "id": "P40527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40527" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Gln193", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin). Localization to the Golgi apparatus appears normal.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Gln209", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "G", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin) and papuamide A (phosphatidylserine-binding cytotoxin). Localization to the Golgi apparatus appears normal.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "L", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin).", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Tyr222", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "May enhance substrate loading. Decreases cell population growth; when associated with V-228 and D-237.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] }, { "sequence_org": "Y", "sequence_mut": "S", "comment": "Does not appear to affect its physical interaction with ANY1. Increases localization to late Golgi compartments. Decreases cell population growth; when associated with V-228 and D-237.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] }, { "sequence_org": "Y", "sequence_mut": "S", "comment": "May enhance substrate loading. Decreases cell population growth; when associated with V-228 and D-237.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Phe228", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "V", "comment": "Decreases cell population growth; when associated with S-222 and D-237.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Glu237", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "D", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin) and papuamide A (phosphatidylserine-binding cytotoxin). Localization to the Golgi apparatus appears normal. Decreases cell population growth; when associated with S-222 and V-228.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Arg247", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin).", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" } ] }, { "sequence_org": "R", "sequence_mut": "L", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin).", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin).", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] }, { "sequence_org": "S", "sequence_mut": "Q", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin).", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] }, { "sequence_org": "S", "sequence_mut": "Q", "comment": "Sensitive to papuamide A (phosphatidylserine-binding cytotoxin). Localization to the Golgi apparatus appears normal.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "453", "end_pos": "453", "site_lbl": "Thr453", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "S", "comment": "Sensitive to papuamide A.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "456", "end_pos": "456", "site_lbl": "Pro456", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "No apparent effect on viability. Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin) and papuamide A (phosphatidylserine-binding cytotoxin). Localization to the Golgi apparatus appears normal.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" } ] }, { "sequence_org": "P", "sequence_mut": "G", "comment": "Inviable.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "457", "end_pos": "457", "site_lbl": "Val457", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin).", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] }, { "sequence_org": "V", "sequence_mut": "E", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin).", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] }, { "sequence_org": "V", "sequence_mut": "F", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin).", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Ser488", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Localization to the Golgi apparatus appears normal.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" } ] }, { "sequence_org": "S", "sequence_mut": "A", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin) and papuamide A (phosphatidylserine-binding cytotoxin).", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" } ] }, { "sequence_org": "S", "sequence_mut": "W", "comment": "Sensitive to duramycin (phosphatidylethanolamine-binding cytotoxin) and papuamide A (phosphatidylserine-binding cytotoxin).", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "34645814", "url": "https://glygen.org/publication/PubMed/34645814" } ] } ] }, { "uniprot_canonical_ac": "P40527-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Asp503", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Inviable.", "evidence": [ { "database": "UniProtKB", "id": "P40527", "url": "https://www.uniprot.org/uniprotkb/P40527" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" }, { "database": "PubMed", "id": "27235400", "url": "https://glygen.org/publication/PubMed/27235400" } ] } ] } ], "record_id": "P40527-1" }, { "uniprot_canonical_ac": "P40530-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 394, "chemical_mass": 45444.0, "gene_names": "PKP1;PKP1", "protein_name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase 1, mitochondrial", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0090126", "name": "branched-chain keto acid dehydrogenase kinase deficiency", "description": "An amino acid metabolic disorder that is characterized by autism, epilepsy, intellectual disability, and reduced levels of branched-chain amino acids that has_material_basis_in homozygous mutation in the branched chain keto acid dehydrogenase kinase gene (BCKDK) on chromosome 16p11.", "url": "https://disease-ontology.org/term/DOID:0090126", "evidence": [ { "id": "0090126", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090126" } ], "weight": 0.0 }, { "disease_id": "DOID:0110207", "name": "Charcot-Marie-Tooth disease X-linked dominant 6", "description": "A Charcot-Marie-Tooth disease X-linked that has_material_basis_in mutation in the PDK3 gene on chromosome Xp22.", "url": "https://disease-ontology.org/term/DOID:0110207", "evidence": [ { "id": "0110207", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110207" } ], "weight": 0.0 }, { "disease_id": "DOID:14228", "name": "oligospermia", "description": "A male fertility issue defined as a low sperm concentration in the ejaculate.", "url": "https://disease-ontology.org/term/DOID:14228", "evidence": [ { "id": "14228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14228" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "pyruvate dehydrogenase (acetyl-transferring) kinase activity", "id": "GO:0004740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004740", "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of glucose metabolic process", "id": "GO:0010906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010906", "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ], "pmid": "" }, { "name": "regulation of pyruvate decarboxylation to acetyl-CoA", "id": "GO:0010510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010510", "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ], "pmid": "" }, { "name": "regulation of mitophagy", "id": "GO:1901524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901524", "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40530-1", "start_pos": "148", "end_pos": "148", "site_lbl": "His148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40530", "url": "https://www.uniprot.org/uniprotkb/P40530" } ] } ] } ], "record_id": "P40530-1" }, { "uniprot_canonical_ac": "P40535-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 587, "chemical_mass": 65264.0, "gene_names": "CST6;ACA2;CST6;SHF1", "protein_name": "ATF/CREB activator 2", "disease": [], "biological_process": [ { "name": "cellular response to oleic acid", "id": "GO:0071400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071400", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" }, { "name": "cellular response to stress", "id": "GO:0033554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033554", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" }, { "name": "cellular response to carbon dioxide", "id": "GO:0071244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071244", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40535-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 104, "start_aa": "Ser", "end_pos": 104, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser104", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 179, "start_aa": "Ser", "end_pos": 179, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser179", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 184, "start_aa": "Ser", "end_pos": 184, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser184", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 192, "start_aa": "Ser", "end_pos": 192, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser192", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Ser199", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 199, "start_aa": "Ser", "end_pos": 199, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser199", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 309, "start_aa": "Ser", "end_pos": 309, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser309", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Ser321", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 321, "start_aa": "Ser", "end_pos": 321, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser321", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Ser322", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 322, "start_aa": "Ser", "end_pos": 322, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser322", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Ser338", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 338, "start_aa": "Ser", "end_pos": 338, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser338", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 344, "start_aa": "Ser", "end_pos": 344, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser344", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Ser348", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 348, "start_aa": "Ser", "end_pos": 348, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser348", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 404, "start_aa": "Ser", "end_pos": 404, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser404", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 407, "start_aa": "Ser", "end_pos": 407, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser407", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 61, "start_aa": "Ser", "end_pos": 61, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser61", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Thr65", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 65, "start_aa": "Thr", "end_pos": 65, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr65", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 70, "start_aa": "Ser", "end_pos": 70, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser70", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Ser86", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 86, "start_aa": "Ser", "end_pos": 86, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser86", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 90, "start_aa": "Ser", "end_pos": 90, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser90", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 96, "start_aa": "Ser", "end_pos": 96, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser96", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40535", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40535" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Ser394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Thr401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "519", "end_pos": "519", "site_lbl": "Ser519", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "552", "end_pos": "552", "site_lbl": "Ser552", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "557", "end_pos": "557", "site_lbl": "Ser557", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "559", "end_pos": "559", "site_lbl": "Thr559", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40535", "url": "https://www.uniprot.org/uniprotkb/P40535" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "579", "end_pos": "579", "site_lbl": "Ser579", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "583", "end_pos": "583", "site_lbl": "Ser583", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "92", "end_pos": "92", "site_lbl": "Thr92", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40535-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Tyr95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001298", "url": "https://www.yeastgenome.org/locus/S000001298" }, { "database": "iPTMnet", "id": "P40535", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40535" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P40535-1" }, { "uniprot_canonical_ac": "P40540-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40540", "url": "https://www.uniprot.org/uniprotkb/P40540" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 141, "chemical_mass": 15907.0, "gene_names": "EMC5;EMC5;KRE27", "protein_name": "ER membrane protein complex subunit 5", "disease": [], "cellular_component": [ { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "P40540", "url": "https://www.uniprot.org/uniprotkb/P40540" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40540", "url": "https://www.uniprot.org/uniprotkb/P40540" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "P40540", "url": "https://www.uniprot.org/uniprotkb/P40540" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "P40540", "url": "https://www.uniprot.org/uniprotkb/P40540" } ], "pmid": "" }, { "name": "protein folding in endoplasmic reticulum", "id": "GO:0034975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034975", "evidence": [ { "database": "UniProtKB", "id": "P40540", "url": "https://www.uniprot.org/uniprotkb/P40540" } ], "pmid": "" }, { "name": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "id": "GO:0045050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045050", "evidence": [ { "database": "UniProtKB", "id": "P40540", "url": "https://www.uniprot.org/uniprotkb/P40540" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40540-1" }, { "uniprot_canonical_ac": "P40541-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1150, "chemical_mass": 133009.0, "gene_names": "IRR1;IRR1;SCC3", "protein_name": "Cohesin subunit SCC3", "disease": [ { "disease_id": "DOID:0060954", "name": "Holoprosencephaly 13, X-linked", "description": "A holoprosencephaly characterized by midline developmental defects that mainly affect the brain and craniofacial structure that has_material_basis_in heterozygous mutation in the STAG2 gene on chromosome Xq25.", "url": "https://disease-ontology.org/term/DOID:0060954", "evidence": [ { "id": "0060954", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060954" } ], "weight": 0.0 }, { "disease_id": "DOID:0080238", "name": "autosomal dominant intellectual developmental disorder 47", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the STAG1 gene on chromosome 3q22.", "url": "https://disease-ontology.org/term/DOID:0080238", "evidence": [ { "id": "0080238", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080238" } ], "weight": 0.0 }, { "disease_id": "DOID:0080865", "name": "primary ovarian insufficiency 8", "description": "A primary ovarian insufficiency that has_material_basis_in homozygous mutation in the STAG3 gene on chromosome 7q22.", "url": "https://disease-ontology.org/term/DOID:0080865", "evidence": [ { "id": "0080865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080865" } ], "weight": 0.0 }, { "disease_id": "DOID:0111845", "name": "Mullegama-Klein-Martinez syndrome", "description": "A syndromic X-linked intellectual disability characterized by global developmental delay with impaired intellectual development and poor speech and commonly associated with ear abnormalities, hearing loss, and dysmorphic facial features that has_material_basis_in heterozygous or hemizygous mutation in the STAG2 gene on chromosome Xq25.", "url": "https://disease-ontology.org/term/DOID:0111845", "evidence": [ { "id": "0111845", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111845" } ], "weight": 0.0 }, { "disease_id": "DOID:0112350", "name": "spermatogenic failure 61", "description": "A spermatogenic failure that is characterized by male infertility due to nonobstructive azoospermia with complete meiotic arrest at the primary spermatocyte stage that has_material_basis_in homozygous or compound heterozygous mutation in the STAG3 gene on chromosome 7q22.1.", "url": "https://disease-ontology.org/term/DOID:0112350", "evidence": [ { "id": "0112350", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112350" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitotic cohesin complex", "id": "GO:0030892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030892", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "cohesin complex", "id": "GO:0008278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008278", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "protein acetylation", "id": "GO:0006473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006473", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "establishment of mitotic sister chromatid cohesion", "id": "GO:0034087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034087", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "sister chromatid cohesion", "id": "GO:0007062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007062", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" }, { "name": "establishment of meiotic sister chromatid cohesion", "id": "GO:0034089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034089", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40541-1", "start_pos": "1093", "end_pos": "1093", "site_lbl": "Ser1093", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Tyr21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Thr264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Ser325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Ser343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "609", "end_pos": "609", "site_lbl": "Ser609", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Ser613", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "623", "end_pos": "623", "site_lbl": "Ser623", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "628", "end_pos": "628", "site_lbl": "Ser628", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40541", "url": "https://www.uniprot.org/uniprotkb/P40541" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40541-1", "start_pos": "884", "end_pos": "884", "site_lbl": "Ser884", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001288", "url": "https://www.yeastgenome.org/locus/S000001288" }, { "database": "iPTMnet", "id": "P40541", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40541" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40541-1" }, { "uniprot_canonical_ac": "P40547-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40547", "url": "https://www.uniprot.org/uniprotkb/P40547" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 921, "chemical_mass": 105491.0, "gene_names": "VID28;GID5;VID28;YIL017W", "protein_name": "GID complex subunit 5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40547", "url": "https://www.uniprot.org/uniprotkb/P40547" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40547", "url": "https://www.uniprot.org/uniprotkb/P40547" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "P40547", "url": "https://www.uniprot.org/uniprotkb/P40547" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "P40547", "url": "https://www.uniprot.org/uniprotkb/P40547" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P40547", "url": "https://www.uniprot.org/uniprotkb/P40547" } ], "pmid": "" }, { "name": "negative regulation of gluconeogenesis", "id": "GO:0045721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045721", "evidence": [ { "database": "UniProtKB", "id": "P40547", "url": "https://www.uniprot.org/uniprotkb/P40547" } ], "pmid": "" }, { "name": "protein catabolic process in the vacuole", "id": "GO:0007039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007039", "evidence": [ { "database": "UniProtKB", "id": "P40547", "url": "https://www.uniprot.org/uniprotkb/P40547" } ], "pmid": "" }, { "name": "ascospore formation", "id": "GO:0030437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030437", "evidence": [ { "database": "UniProtKB", "id": "P40547", "url": "https://www.uniprot.org/uniprotkb/P40547" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40547-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Ser577", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 577, "start_aa": "Ser", "end_pos": 577, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser577", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40547", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40547" } ] } ] }, { "uniprot_canonical_ac": "P40547-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Ser222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001279", "url": "https://www.yeastgenome.org/locus/S000001279" }, { "database": "iPTMnet", "id": "P40547", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40547" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40547-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40547", "url": "https://www.uniprot.org/uniprotkb/P40547" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40547", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40547" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001279", "url": "https://www.yeastgenome.org/locus/S000001279" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40547-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Ser228", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001279", "url": "https://www.yeastgenome.org/locus/S000001279" }, { "database": "iPTMnet", "id": "P40547", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40547" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40547-1", "start_pos": "835", "end_pos": "835", "site_lbl": "Ser835", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001279", "url": "https://www.yeastgenome.org/locus/S000001279" }, { "database": "iPTMnet", "id": "P40547", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40547" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P40547-1" }, { "uniprot_canonical_ac": "P40548-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 159, "chemical_mass": 18306.0, "gene_names": "SNL1;SNL1", "protein_name": "HSP70 co-chaperone SNL1", "disease": [], "biological_process": [ { "name": "nuclear pore organization", "id": "GO:0006999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006999", "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40548-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001278", "url": "https://www.yeastgenome.org/locus/S000001278" }, { "database": "iPTMnet", "id": "P40548", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40548" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40548-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Glu112", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Strongly reduces interaction with HSP70 family members.", "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" }, { "database": "PubMed", "id": "12105220", "url": "https://glygen.org/publication/PubMed/12105220" } ] } ] }, { "uniprot_canonical_ac": "P40548-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Arg141", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Strongly reduces interaction with HSP70 family members.", "evidence": [ { "database": "UniProtKB", "id": "P40548", "url": "https://www.uniprot.org/uniprotkb/P40548" }, { "database": "PubMed", "id": "12105220", "url": "https://glygen.org/publication/PubMed/12105220" } ] } ] } ], "record_id": "P40548-1" }, { "uniprot_canonical_ac": "P40553-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40553", "url": "https://www.uniprot.org/uniprotkb/P40553" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 215, "chemical_mass": 24120.0, "gene_names": "DOT5;DOT5", "protein_name": "Peroxiredoxin DOT5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40553", "url": "https://www.uniprot.org/uniprotkb/P40553" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40553", "url": "https://www.uniprot.org/uniprotkb/P40553" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P40553", "url": "https://www.uniprot.org/uniprotkb/P40553" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P40553", "url": "https://www.uniprot.org/uniprotkb/P40553" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P40553", "url": "https://www.uniprot.org/uniprotkb/P40553" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "P40553", "url": "https://www.uniprot.org/uniprotkb/P40553" } ], "pmid": "" } ], "molecular_function": [ { "name": "thioredoxin peroxidase activity", "id": "GO:0008379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008379", "evidence": [ { "database": "UniProtKB", "id": "P40553", "url": "https://www.uniprot.org/uniprotkb/P40553" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40553-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Thr104", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 104, "start_aa": "Thr", "end_pos": 104, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr104", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P40553-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Thr168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001272", "url": "https://www.yeastgenome.org/locus/S000001272" }, { "database": "iPTMnet", "id": "P40553", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40553" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40553-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001272", "url": "https://www.yeastgenome.org/locus/S000001272" }, { "database": "iPTMnet", "id": "P40553", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40553" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40553-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001272", "url": "https://www.yeastgenome.org/locus/S000001272" }, { "database": "iPTMnet", "id": "P40553", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40553" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40553-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Thr30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40553", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40553" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001272", "url": "https://www.yeastgenome.org/locus/S000001272" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40553-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Cys107", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No TPx activity, no effect on DOT activity.", "evidence": [ { "database": "UniProtKB", "id": "P40553", "url": "https://www.uniprot.org/uniprotkb/P40553" }, { "database": "PubMed", "id": "12730197", "url": "https://glygen.org/publication/PubMed/12730197" }, { "database": "PubMed", "id": "12925864", "url": "https://glygen.org/publication/PubMed/12925864" }, { "database": "PubMed", "id": "10681558", "url": "https://glygen.org/publication/PubMed/10681558" } ] } ] }, { "uniprot_canonical_ac": "P40553-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Cys112", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No TPx activity, no effect on DOT activity.", "evidence": [ { "database": "UniProtKB", "id": "P40553", "url": "https://www.uniprot.org/uniprotkb/P40553" }, { "database": "PubMed", "id": "12730197", "url": "https://glygen.org/publication/PubMed/12730197" }, { "database": "PubMed", "id": "12925864", "url": "https://glygen.org/publication/PubMed/12925864" } ] } ] } ], "record_id": "P40553-1" }, { "uniprot_canonical_ac": "P40554-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 99, "chemical_mass": 11028.0, "gene_names": "URM1;URM1", "protein_name": "Ubiquitin-related modifier 1", "disease": [], "biological_process": [ { "name": "tRNA wobble position uridine thiolation", "id": "GO:0002143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002143", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" }, { "name": "tRNA thio-modification", "id": "GO:0034227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034227", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" }, { "name": "protein urmylation", "id": "GO:0032447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032447", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" }, { "name": "invasive growth in response to glucose limitation", "id": "GO:0001403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001403", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" }, { "name": "cell budding", "id": "GO:0007114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007114", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" }, { "name": "protein tag activity", "id": "GO:0031386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031386", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" }, { "name": "sulfur carrier activity", "id": "GO:0097163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097163", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40554-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Gly99", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "", "comment": "Abolishes URM1 conjugate formation.", "evidence": [ { "database": "UniProtKB", "id": "P40554", "url": "https://www.uniprot.org/uniprotkb/P40554" }, { "database": "PubMed", "id": "10713047", "url": "https://glygen.org/publication/PubMed/10713047" } ] } ] } ], "record_id": "P40554-1" }, { "uniprot_canonical_ac": "P40556-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40556", "url": "https://www.uniprot.org/uniprotkb/P40556" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 373, "chemical_mass": 41954.0, "gene_names": "YIA6;NDT1;YIA6", "protein_name": "Mitochondrial nicotinamide adenine dinucleotide transporter 1", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40556", "url": "https://www.uniprot.org/uniprotkb/P40556" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P40556", "url": "https://www.uniprot.org/uniprotkb/P40556" } ], "pmid": "" } ], "molecular_function": [ { "name": "NAD transmembrane transporter activity", "id": "GO:0051724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051724", "evidence": [ { "database": "UniProtKB", "id": "P40556", "url": "https://www.uniprot.org/uniprotkb/P40556" } ], "pmid": "" } ], "biological_process": [ { "name": "pyruvate import into mitochondria", "id": "GO:0006850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006850", "evidence": [ { "database": "UniProtKB", "id": "P40556", "url": "https://www.uniprot.org/uniprotkb/P40556" } ], "pmid": "" }, { "name": "mitochondrial NAD transmembrane transport", "id": "GO:1990549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990549", "evidence": [ { "database": "UniProtKB", "id": "P40556", "url": "https://www.uniprot.org/uniprotkb/P40556" } ], "pmid": "" }, { "name": "NAD transmembrane transport", "id": "GO:0035352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035352", "evidence": [ { "database": "UniProtKB", "id": "P40556", "url": "https://www.uniprot.org/uniprotkb/P40556" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40556-1" }, { "uniprot_canonical_ac": "P40557-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40557", "url": "https://www.uniprot.org/uniprotkb/P40557" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 701, "chemical_mass": 81219.0, "gene_names": "EPS1;EPS1;YIA5W", "protein_name": "ER-retained PMA1-suppressing protein 1", "disease": [], "molecular_function": [ { "name": "protein-disulfide reductase (glutathione) activity", "id": "GO:0019153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019153", "evidence": [ { "database": "UniProtKB", "id": "P40557", "url": "https://www.uniprot.org/uniprotkb/P40557" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P40557", "url": "https://www.uniprot.org/uniprotkb/P40557" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "P40557", "url": "https://www.uniprot.org/uniprotkb/P40557" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40557", "url": "https://www.uniprot.org/uniprotkb/P40557" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P40557", "url": "https://www.uniprot.org/uniprotkb/P40557" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P40557", "url": "https://www.uniprot.org/uniprotkb/P40557" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "P40557", "url": "https://www.uniprot.org/uniprotkb/P40557" } ], "pmid": "" }, { "name": "protein retention in ER lumen", "id": "GO:0006621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006621", "evidence": [ { "database": "UniProtKB", "id": "P40557", "url": "https://www.uniprot.org/uniprotkb/P40557" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40557-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Asn264", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 264, "start_aa": "Asn", "end_pos": 264, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn264", "evidence": [ { "id": "P40557", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40557#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40557-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Asn299", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 299, "start_aa": "Asn", "end_pos": 299, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn299", "evidence": [ { "id": "P40557", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40557#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40557-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Asn370", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 370, "start_aa": "Asn", "end_pos": 370, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn370", "evidence": [ { "id": "P40557", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40557#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40557-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Asn85", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 85, "start_aa": "Asn", "end_pos": 85, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn85", "evidence": [ { "id": "P40557", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40557#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P40557-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001267", "url": "https://www.yeastgenome.org/locus/S000001267" }, { "database": "iPTMnet", "id": "P40557", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40557" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40557-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Thr149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001267", "url": "https://www.yeastgenome.org/locus/S000001267" }, { "database": "iPTMnet", "id": "P40557", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40557" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40557-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001267", "url": "https://www.yeastgenome.org/locus/S000001267" }, { "database": "iPTMnet", "id": "P40557", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40557" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P40557-1" }, { "uniprot_canonical_ac": "P40558-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 293, "chemical_mass": 31922.0, "gene_names": "CFD1;CFD1;DRE3;RIX19;YIA3W", "protein_name": "Cytosolic Fe-S cluster assembly factor CFD1", "disease": [], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "pmid": "" }, { "name": "ATP-dependent FeS chaperone activity", "id": "GO:0140663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140663", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "pmid": "" }, { "name": "cytosolic [4Fe-4S] assembly scaffold complex", "id": "GO:1904564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904564", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40558-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Thr165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001265", "url": "https://www.yeastgenome.org/locus/S000001265" }, { "database": "iPTMnet", "id": "P40558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Thr166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001265", "url": "https://www.yeastgenome.org/locus/S000001265" }, { "database": "iPTMnet", "id": "P40558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Ser169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001265", "url": "https://www.yeastgenome.org/locus/S000001265" }, { "database": "iPTMnet", "id": "P40558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Thr172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001265", "url": "https://www.yeastgenome.org/locus/S000001265" }, { "database": "iPTMnet", "id": "P40558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Thr276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001265", "url": "https://www.yeastgenome.org/locus/S000001265" }, { "database": "iPTMnet", "id": "P40558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Thr278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001265", "url": "https://www.yeastgenome.org/locus/S000001265" }, { "database": "iPTMnet", "id": "P40558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Ser291", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40558" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001265", "url": "https://www.yeastgenome.org/locus/S000001265" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Cys182", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Does not impair function.", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Cys201", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of function and disrupts heterotetramer formation.", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Cys204", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of function and disrupts heterotetramer formation.", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Cys207", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Does not impair function.", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Lys31", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ] } ] }, { "uniprot_canonical_ac": "P40558-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Thr86", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P40558", "url": "https://www.uniprot.org/uniprotkb/P40558" } ] } ] } ], "record_id": "P40558-1" }, { "uniprot_canonical_ac": "P40562-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 993, "chemical_mass": 114058.0, "gene_names": "MPH1;MPH1;YIB2C", "protein_name": "ATP-dependent DNA helicase MPH1", "disease": [ { "disease_id": "DOID:0050629", "name": "Aicardi-Goutieres syndrome", "description": "A syndrome that is a genetically heterogeneous encephalopathy characterized in its most severe form by cerebral atrophy, leukodystrophy, intracranial calcifications, chronic cerebrospinal fluid lymphocytosis, increased CSF alpha-interferon, and negative serologic investigations for common prenatal infections.", "url": "https://disease-ontology.org/term/DOID:0050629", "evidence": [ { "id": "0050629", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050629" } ], "weight": 0.0 }, { "disease_id": "DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue.", "url": "https://disease-ontology.org/term/DOID:0050865", "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ], "weight": 0.0 }, { "disease_id": "DOID:0061065", "name": "immunodeficiency 95", "description": "A primary immunodeficiency disease that is characterized by the onset of recurrent and severe viral respiratory infections in infancy or early childhood and that has_material_basis_in homozygous loss-of-function mutation in the IFIH1 gene on chromosome 2q24.", "url": "https://disease-ontology.org/term/DOID:0061065", "evidence": [ { "id": "0061065", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061065" } ], "weight": 0.0 }, { "disease_id": "DOID:0080872", "name": "primary ovarian insufficiency 15", "description": "A primary ovarian insufficiency that is characterized by onset of oligomenorrhea in the third decade of life, with small ovaries, reduced number of follicles, and elevated gonadotropic hormones and that has_material_basis_in homozygous mutation in the FANCM gene on chromosome 14q21.", "url": "https://disease-ontology.org/term/DOID:0080872", "evidence": [ { "id": "0080872", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080872" } ], "weight": 0.0 }, { "disease_id": "DOID:0111916", "name": "spermatogenic failure 28", "description": "A spermatogenic failure characterized by nonobstructive azoospermia and a Sertoli cell-only phenotype in testes that has_material_basis_in homozygous or compound heterozygous mutation in the FANCM gene on chromosome 14q21.2.", "url": "https://disease-ontology.org/term/DOID:0111916", "evidence": [ { "id": "0111916", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111916" } ], "weight": 0.0 }, { "disease_id": "DOID:13636", "name": "Fanconi anemia", "description": "A congenital hypoplastic anemia characterized by progressive pancytopenia with bone marrow failure, variable congenital malformations and predisposition to develop hematological or solid tumors. It is a result of a genetic defect in a cluster of proteins responsible for DNA repair.", "url": "https://disease-ontology.org/term/DOID:13636", "evidence": [ { "id": "13636", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13636" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "DNA/RNA helicase activity", "id": "GO:0033677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033677", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "four-way junction helicase activity", "id": "GO:0009378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009378", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "flap-structured DNA binding", "id": "GO:0070336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070336", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" } ], "biological_process": [ { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "recombinational repair", "id": "GO:0000725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000725", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "DNA replication, Okazaki fragment processing", "id": "GO:0033567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033567", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "double-strand break repair via synthesis-dependent strand annealing", "id": "GO:0045003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045003", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "negative regulation of strand invasion", "id": "GO:0060543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060543", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" }, { "name": "donor selection", "id": "GO:0007535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007535", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40562-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Thr242", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 242, "start_aa": "Thr", "end_pos": 242, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr242", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001441", "url": "https://www.yeastgenome.org/locus/S000001441" }, { "database": "iPTMnet", "id": "P40562", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40562" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "540", "end_pos": "540", "site_lbl": "Thr540", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40562", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40562" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001441", "url": "https://www.yeastgenome.org/locus/S000001441" }, { "database": "PubMed", "id": "27017623", "url": "https://glygen.org/publication/PubMed/27017623" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Ser542", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40562", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40562" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001441", "url": "https://www.yeastgenome.org/locus/S000001441" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "543", "end_pos": "543", "site_lbl": "Ser543", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001441", "url": "https://www.yeastgenome.org/locus/S000001441" }, { "database": "iPTMnet", "id": "P40562", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40562" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001441", "url": "https://www.yeastgenome.org/locus/S000001441" }, { "database": "iPTMnet", "id": "P40562", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40562" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "776", "end_pos": "776", "site_lbl": "Thr776", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" }, { "database": "iPTMnet", "id": "P40562", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40562" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes the interaction with FKH1; when associated with A-785.", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "785", "end_pos": "785", "site_lbl": "Thr785", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" }, { "database": "iPTMnet", "id": "P40562", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40562" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes the interaction with FKH1; when associated with A-776.", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "894", "end_pos": "894", "site_lbl": "Ser894", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001441", "url": "https://www.yeastgenome.org/locus/S000001441" }, { "database": "iPTMnet", "id": "P40562", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40562" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "973", "end_pos": "973", "site_lbl": "Ser973", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001441", "url": "https://www.yeastgenome.org/locus/S000001441" }, { "database": "iPTMnet", "id": "P40562", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40562" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001441", "url": "https://www.yeastgenome.org/locus/S000001441" }, { "database": "iPTMnet", "id": "P40562", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40562" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "774", "end_pos": "774", "site_lbl": "Asp774", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduces the interaction with FKH1; when associated with A-785.", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "775", "end_pos": "775", "site_lbl": "Ser775", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces the interaction with FKH1; when associated with A-785.", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "777", "end_pos": "777", "site_lbl": "Glu777", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Reduces the interaction with FKH1; when associated with A-785.", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "782", "end_pos": "782", "site_lbl": "Ser782", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces the interaction with FKH1; when associated with A-776.", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "784", "end_pos": "784", "site_lbl": "Glu784", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Reduces the interaction with FKH1; when associated with A-776.", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] }, { "uniprot_canonical_ac": "P40562-1", "start_pos": "786", "end_pos": "786", "site_lbl": "Glu786", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Reduces the interaction with FKH1; when associated with A-776.", "evidence": [ { "database": "UniProtKB", "id": "P40562", "url": "https://www.uniprot.org/uniprotkb/P40562" }, { "database": "PubMed", "id": "27257873", "url": "https://glygen.org/publication/PubMed/27257873" } ] } ] } ], "record_id": "P40562-1" }, { "uniprot_canonical_ac": "P40564-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40564", "url": "https://www.uniprot.org/uniprotkb/P40564" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 432, "chemical_mass": 48575.0, "gene_names": "DJP1;DJP1;ICS1;PAS22;YIB4W", "protein_name": "DnaJ-like protein 1", "disease": [], "biological_process": [ { "name": "protein insertion into mitochondrial outer membrane", "id": "GO:0045040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045040", "evidence": [ { "database": "UniProtKB", "id": "P40564", "url": "https://www.uniprot.org/uniprotkb/P40564" } ], "pmid": "" }, { "name": "protein targeting to mitochondrion", "id": "GO:0006626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006626", "evidence": [ { "database": "UniProtKB", "id": "P40564", "url": "https://www.uniprot.org/uniprotkb/P40564" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix", "id": "GO:0016558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016558", "evidence": [ { "database": "UniProtKB", "id": "P40564", "url": "https://www.uniprot.org/uniprotkb/P40564" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40564", "url": "https://www.uniprot.org/uniprotkb/P40564" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P40564", "url": "https://www.uniprot.org/uniprotkb/P40564" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40564", "url": "https://www.uniprot.org/uniprotkb/P40564" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P40564", "url": "https://www.uniprot.org/uniprotkb/P40564" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "P40564", "url": "https://www.uniprot.org/uniprotkb/P40564" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "P40564", "url": "https://www.uniprot.org/uniprotkb/P40564" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40564-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Thr131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40564" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40564-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001443", "url": "https://www.yeastgenome.org/locus/S000001443" }, { "database": "iPTMnet", "id": "P40564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40564" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40564-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Thr166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001443", "url": "https://www.yeastgenome.org/locus/S000001443" }, { "database": "iPTMnet", "id": "P40564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40564" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40564-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Thr167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001443", "url": "https://www.yeastgenome.org/locus/S000001443" }, { "database": "iPTMnet", "id": "P40564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40564" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40564-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40564" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001443", "url": "https://www.yeastgenome.org/locus/S000001443" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40564-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Thr172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001443", "url": "https://www.yeastgenome.org/locus/S000001443" }, { "database": "iPTMnet", "id": "P40564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40564" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P40564-1" }, { "uniprot_canonical_ac": "P40565-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 148, "chemical_mass": 17098.0, "gene_names": "IST3;IST3;SNU17;YIB5W", "protein_name": "U2 snRNP component IST3", "disease": [], "biological_process": [ { "name": "generation of catalytic spliceosome for first transesterification step", "id": "GO:0000349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000349", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" }, { "name": "maintenance of RNA location", "id": "GO:0051237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051237", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" }, { "name": "RES complex", "id": "GO:0070274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070274", "evidence": [ { "database": "UniProtKB", "id": "P40565", "url": "https://www.uniprot.org/uniprotkb/P40565" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40565-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001444", "url": "https://www.yeastgenome.org/locus/S000001444" }, { "database": "iPTMnet", "id": "P40565", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40565" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40565-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001444", "url": "https://www.yeastgenome.org/locus/S000001444" }, { "database": "iPTMnet", "id": "P40565", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40565" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40565-1" }, { "uniprot_canonical_ac": "P40571-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40571", "url": "https://www.uniprot.org/uniprotkb/P40571" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 144, "chemical_mass": 16344.0, "gene_names": "RPR2;RPR2", "protein_name": "Ribonuclease P protein subunit RPR2", "disease": [], "cellular_component": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "P40571", "url": "https://www.uniprot.org/uniprotkb/P40571" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "P40571", "url": "https://www.uniprot.org/uniprotkb/P40571" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "P40571", "url": "https://www.uniprot.org/uniprotkb/P40571" } ], "pmid": "" }, { "name": "intronic box C/D snoRNA processing", "id": "GO:0034965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034965", "evidence": [ { "database": "UniProtKB", "id": "P40571", "url": "https://www.uniprot.org/uniprotkb/P40571" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P40571", "url": "https://www.uniprot.org/uniprotkb/P40571" } ], "pmid": "" }, { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "P40571", "url": "https://www.uniprot.org/uniprotkb/P40571" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P40571-1" }, { "uniprot_canonical_ac": "P40581-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40581", "url": "https://www.uniprot.org/uniprotkb/P40581" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 163, "chemical_mass": 18641.0, "gene_names": "HYR1;GPX3;HYR1;ORP1", "protein_name": "Glutathione peroxidase-like peroxiredoxin HYR1", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0112298", "name": "spondylometaphyseal dysplasia Sedaghatian type", "description": "A spondylometaphyseal dysplasia characterized by neonatal lethality, severe metaphyseal chondrodysplasia with mild limb shortening, platyspondyly, delayed epiphyseal ossification, irregular iliac crests, pulmonary hemorrhage, severe hypotonia and cardiorespiratory problems that has_material_basis_in homozygous or compound heterozygous mutation in the GPX4 gene on chromosome 19p13.3.", "url": "https://disease-ontology.org/term/DOID:0112298", "evidence": [ { "id": "0112298", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112298" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40581", "url": "https://www.uniprot.org/uniprotkb/P40581" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P40581", "url": "https://www.uniprot.org/uniprotkb/P40581" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "P40581", "url": "https://www.uniprot.org/uniprotkb/P40581" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40581", "url": "https://www.uniprot.org/uniprotkb/P40581" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P40581", "url": "https://www.uniprot.org/uniprotkb/P40581" } ], "pmid": "" } ], "molecular_function": [ { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "P40581", "url": "https://www.uniprot.org/uniprotkb/P40581" } ], "pmid": "" }, { "name": "phospholipid-hydroperoxide glutathione peroxidase activity", "id": "GO:0047066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047066", "evidence": [ { "database": "UniProtKB", "id": "P40581", "url": "https://www.uniprot.org/uniprotkb/P40581" } ], "pmid": "" }, { "name": "thioredoxin-dependent peroxiredoxin activity", "id": "GO:0140824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140824", "evidence": [ { "database": "UniProtKB", "id": "P40581", "url": "https://www.uniprot.org/uniprotkb/P40581" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40581-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40581" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001476", "url": "https://www.yeastgenome.org/locus/S000001476" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40581-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Ser150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001476", "url": "https://www.yeastgenome.org/locus/S000001476" }, { "database": "iPTMnet", "id": "P40581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40581" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40581-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001476", "url": "https://www.yeastgenome.org/locus/S000001476" }, { "database": "iPTMnet", "id": "P40581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40581" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40581-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Cys82", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Loss of enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P40581", "url": "https://www.uniprot.org/uniprotkb/P40581" }, { "database": "PubMed", "id": "18767166", "url": "https://glygen.org/publication/PubMed/18767166" } ] } ] } ], "record_id": "P40581-1" }, { "uniprot_canonical_ac": "P40825-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 983, "chemical_mass": 110059.0, "gene_names": "ALA1;ALA1;CDC64", "protein_name": "Alanine--tRNA ligase, mitochondrial", "disease": [ { "disease_id": "DOID:0050753", "name": "cerebellar ataxia", "description": "A hereditary ataxia that is characterized by ataxia originating in the cerebellum.", "url": "https://disease-ontology.org/term/DOID:0050753", "evidence": [ { "id": "0050753", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050753" } ], "weight": 0.0 }, { "disease_id": "DOID:0061023", "name": "nonphotosensitive trichothiodystrophy 8", "description": "A nonphotosensitive trichothiodystrophy that is characterized by brittle hair and nails and scaly skin, accompanied by failure to thrive, microcephaly, and neuromotor developmental delay that has_material_basis_in compound heterozygous mutation in the AARS1 gene on chromosome 16q22.", "url": "https://disease-ontology.org/term/DOID:0061023", "evidence": [ { "id": "0061023", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061023" } ], "weight": 0.0 }, { "disease_id": "DOID:0070396", "name": "progressive leukoencephalopathy with ovarian failure", "description": "An leukodystrophy characterized by loss of motor and cognitive skills, usually with onset in young adulthood, that has_material_basis_in compound heterozygous mutation in the AARS2 gene on chromosome 6p21.", "url": "https://disease-ontology.org/term/DOID:0070396", "evidence": [ { "id": "0070396", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070396" } ], "weight": 0.0 }, { "disease_id": "DOID:0080451", "name": "developmental and epileptic encephalopathy 29", "description": "A developmental and epileptic encephalopathy characterized by onset in the first months of life of refractory myoclonic seizures, poor overall growth, congenital microcephaly with cerebral atrophy and impaired myelination on brain imaging, spasticity with abnormal movements, peripheral neuropathy, and poor visual fixation that has_material_basis_in homozygous or compound heterozygous mutation in the AARS1 gene on chromosome 16q22.", "url": "https://disease-ontology.org/term/DOID:0080451", "evidence": [ { "id": "0080451", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080451" } ], "weight": 0.0 }, { "disease_id": "DOID:0110177", "name": "Charcot-Marie-Tooth disease axonal type 2N", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in heterozygous mutation in the AARS gene on chromosome 16q21.", "url": "https://disease-ontology.org/term/DOID:0110177", "evidence": [ { "id": "0110177", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110177" } ], "weight": 0.0 }, { "disease_id": "DOID:0111479", "name": "combined oxidative phosphorylation deficiency 8", "description": "A combined oxidative phosphorylation deficiency characterized by lethal infantile hypertrophic cardiomyopathy and in some cases subtle skeletal muscle and brain involvement that has_material_basis_in homozygous or compound heterozygous mutation in the AARS2 gene on chromosome 6p21.1.", "url": "https://disease-ontology.org/term/DOID:0111479", "evidence": [ { "id": "0111479", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111479" } ], "weight": 0.0 }, { "disease_id": "DOID:10223", "name": "dermatomyositis", "description": "A myositis that results_in inflammation located_in muscle or located_in skin where a skin rash is often seen prior to the onset of muscle weakness. The disease may result from either a viral infection or an autoimmune reaction.", "url": "https://disease-ontology.org/term/DOID:10223", "evidence": [ { "id": "10223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10223" } ], "weight": 0.0 }, { "disease_id": "DOID:10579", "name": "leukodystrophy", "description": "A cerebral degeneration characterized by dysfunction of the white matter of the brain.", "url": "https://disease-ontology.org/term/DOID:10579", "evidence": [ { "id": "10579", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10579" } ], "weight": 0.0 }, { "disease_id": "DOID:10595", "name": "Charcot-Marie-Tooth disease", "description": "A neuromuscular disease that is characterized by a slowly progressive degeneration of the muscles of the foot, lower leg, hand and forearm.", "url": "https://disease-ontology.org/term/DOID:10595", "evidence": [ { "id": "10595", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10595" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:7319", "name": "axonal neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:7319", "evidence": [ { "id": "7319", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7319" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "aminoacyl-tRNA deacylase activity", "id": "GO:0002161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002161", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "pmid": "" }, { "name": "sequence-specific mRNA binding", "id": "GO:1990825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990825", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "pmid": "" }, { "name": "alanine-tRNA ligase activity", "id": "GO:0004813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004813", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial alanyl-tRNA aminoacylation", "id": "GO:0070143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070143", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "pmid": "" }, { "name": "alanyl-tRNA aminoacylation", "id": "GO:0006419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006419", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40825-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Ser278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Thr293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Tyr308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Ser504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Ser522", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "612", "end_pos": "612", "site_lbl": "Ser612", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "666", "end_pos": "666", "site_lbl": "Ser666", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "804", "end_pos": "804", "site_lbl": "Ser804", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "881", "end_pos": "881", "site_lbl": "Ser881", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "899", "end_pos": "899", "site_lbl": "Ser899", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "904", "end_pos": "904", "site_lbl": "Ser904", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "943", "end_pos": "943", "site_lbl": "Ser943", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40825-1", "start_pos": "975", "end_pos": "975", "site_lbl": "Ser975", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40825", "url": "https://www.uniprot.org/uniprotkb/P40825" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005862", "url": "https://www.yeastgenome.org/locus/S000005862" }, { "database": "iPTMnet", "id": "P40825", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40825" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40825-1" }, { "uniprot_canonical_ac": "P40850-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 830, "chemical_mass": 94495.0, "gene_names": "MKT1;MKT1;N2302", "protein_name": "Post-transcriptional regulator MKT1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" }, { "name": "regulation of mating type switching", "id": "GO:0031494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031494", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA endonuclease activity", "id": "GO:0004520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004520", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40850-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Ser358", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 358, "start_aa": "Ser", "end_pos": 358, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser358", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40850", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40850" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Ser361", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 361, "start_aa": "Ser", "end_pos": 361, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser361", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40850", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40850" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 362, "start_aa": "Ser", "end_pos": 362, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser362", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40850", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40850" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Ser364", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 364, "start_aa": "Ser", "end_pos": 364, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser364", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40850", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40850" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 365, "start_aa": "Ser", "end_pos": 365, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser365", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40850", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40850" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 367, "start_aa": "Ser", "end_pos": 367, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser367", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40850", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40850" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Ser368", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 368, "start_aa": "Ser", "end_pos": 368, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser368", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40850", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40850" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 369, "start_aa": "Ser", "end_pos": 369, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser369", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40850", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40850" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Ser371", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 371, "start_aa": "Ser", "end_pos": 371, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser371", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P40850", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P40850" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Thr374", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Thr375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Ser381", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005029", "url": "https://www.yeastgenome.org/locus/S000005029" }, { "database": "iPTMnet", "id": "P40850", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40850" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40850-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Asp32", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Decreases gene expression from the ho locus.", "evidence": [ { "database": "UniProtKB", "id": "P40850", "url": "https://www.uniprot.org/uniprotkb/P40850" }, { "database": "PubMed", "id": "15082763", "url": "https://glygen.org/publication/PubMed/15082763" } ] } ] } ], "record_id": "P40850-1" }, { "uniprot_canonical_ac": "P40851-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1208, "chemical_mass": 138332.0, "gene_names": "AXL1;AXL1;FUS5;P9642.4;STE22", "protein_name": "A-factor-processing protease AXL1", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" } ], "pmid": "" }, { "name": "cytogamy", "id": "GO:0000755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000755", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" } ], "pmid": "" }, { "name": "axial cellular bud site selection", "id": "GO:0007120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007120", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" } ], "pmid": "" }, { "name": "peptide pheromone maturation", "id": "GO:0007323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007323", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40851-1", "start_pos": "1134", "end_pos": "1134", "site_lbl": "Tyr1134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40851" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40851-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Thr164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006326", "url": "https://www.yeastgenome.org/locus/S000006326" }, { "database": "iPTMnet", "id": "P40851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40851" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40851-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Ser262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P40851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40851" } ] } ] }, { "uniprot_canonical_ac": "P40851-1", "start_pos": "68", "end_pos": "68", "site_lbl": "His68", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes protease activity and A-factor processing, but not bud-site selection.", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" }, { "database": "PubMed", "id": "7569998", "url": "https://glygen.org/publication/PubMed/7569998" } ] } ] }, { "uniprot_canonical_ac": "P40851-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Glu71", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Abolishes protease activity and A-factor processing, but not bud-site selection.", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" }, { "database": "PubMed", "id": "7569998", "url": "https://glygen.org/publication/PubMed/7569998" } ] }, { "sequence_org": "E", "sequence_mut": "D", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P40851", "url": "https://www.uniprot.org/uniprotkb/P40851" }, { "database": "PubMed", "id": "7569998", "url": "https://glygen.org/publication/PubMed/7569998" } ] } ] } ], "record_id": "P40851-1" }, { "uniprot_canonical_ac": "P40892-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40892", "url": "https://www.uniprot.org/uniprotkb/P40892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 196, "chemical_mass": 21480.0, "gene_names": "HRA196;J0224", "protein_name": "Putative acetyltransferase YJL218W", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40892", "url": "https://www.uniprot.org/uniprotkb/P40892" } ], "pmid": "" } ], "molecular_function": [ { "name": "galactoside O-acetyltransferase activity", "id": "GO:0008870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008870", "evidence": [ { "database": "UniProtKB", "id": "P40892", "url": "https://www.uniprot.org/uniprotkb/P40892" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40892-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003754", "url": "https://www.yeastgenome.org/locus/S000003754" }, { "database": "iPTMnet", "id": "P40892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40892" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40892-1" }, { "uniprot_canonical_ac": "P40917-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 295, "chemical_mass": 32975.0, "gene_names": "CIN5;CIN5;HAL6;OR26.18;SDS15;YAP4", "protein_name": "AP-1-like transcription factor YAP4", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" }, { "name": "hyperosmotic salinity response", "id": "GO:0042538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042538", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" }, { "name": "hyperosmotic response", "id": "GO:0006972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006972", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40917-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Thr189", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 189, "start_aa": "Thr", "end_pos": 189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr189", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Thr192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "19774548", "url": "https://glygen.org/publication/PubMed/19774548" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19774548", "url": "https://glygen.org/publication/PubMed/19774548" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Thr198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Thr199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Ser210", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Ser280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Thr77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Tyr83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Thr87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Ser89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40917", "url": "https://www.uniprot.org/uniprotkb/P40917" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40917-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005554", "url": "https://www.yeastgenome.org/locus/S000005554" }, { "database": "iPTMnet", "id": "P40917", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40917" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40917-1" }, { "uniprot_canonical_ac": "P40959-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 511, "chemical_mass": 59657.0, "gene_names": "MVP1;MVP1;YM8270.06", "protein_name": "Sorting nexin MVP1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "pmid": "" } ], "biological_process": [ { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "pmid": "" }, { "name": "plasma membrane tubulation", "id": "GO:0097320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097320", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40959-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Ser162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40959", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40959" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004606", "url": "https://www.yeastgenome.org/locus/S000004606" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40959-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004606", "url": "https://www.yeastgenome.org/locus/S000004606" }, { "database": "iPTMnet", "id": "P40959", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40959" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40959-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Thr43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004606", "url": "https://www.yeastgenome.org/locus/S000004606" }, { "database": "iPTMnet", "id": "P40959", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40959" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40959-1", "start_pos": "509", "end_pos": "509", "site_lbl": "Ser509", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40959", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40959" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004606", "url": "https://www.yeastgenome.org/locus/S000004606" } ] } ] }, { "uniprot_canonical_ac": "P40959-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Arg172", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Disprupts localization to endosomal system.", "evidence": [ { "database": "UniProtKB", "id": "P40959", "url": "https://www.uniprot.org/uniprotkb/P40959" }, { "database": "PubMed", "id": "24567361", "url": "https://glygen.org/publication/PubMed/24567361" } ] } ] } ], "record_id": "P40959-1" }, { "uniprot_canonical_ac": "P40961-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 287, "chemical_mass": 31427.0, "gene_names": "PHB1;PHB1;PHB", "protein_name": "Prohibitin-1", "disease": [ { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:8029", "name": "sporadic breast cancer", "description": "A breast carcinoma that occurs in people who do not have a family history of that cancer or an inherited change in their DNA that would increase their risk for that cancer.", "url": "https://disease-ontology.org/term/DOID:8029", "evidence": [ { "id": "8029", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8029" } ], "weight": 0.0 }, { "disease_id": "DOID:8634", "name": "prostate carcinoma in situ", "description": "An in situ carcinoma that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:8634", "evidence": [ { "id": "8634", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8634" } ], "weight": 0.0 }, { "disease_id": "DOID:8991", "name": "cervix uteri carcinoma in situ", "description": "An uterus carcinoma in situ that is located_in the uterine cervix.", "url": "https://disease-ontology.org/term/DOID:8991", "evidence": [ { "id": "8991", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8991" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "pmid": "" } ], "biological_process": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "pmid": "" }, { "name": "negative regulation of proteolysis", "id": "GO:0045861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045861", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "pmid": "" }, { "name": "substrate localization to autophagosome", "id": "GO:0061753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061753", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "pmid": "" }, { "name": "inner mitochondrial membrane organization", "id": "GO:0007007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007007", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "pmid": "" }, { "name": "mitochondrion inheritance", "id": "GO:0000001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000001", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40961-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003364", "url": "https://www.yeastgenome.org/locus/S000003364" }, { "database": "iPTMnet", "id": "P40961", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40961" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40961-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Thr80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003364", "url": "https://www.yeastgenome.org/locus/S000003364" }, { "database": "iPTMnet", "id": "P40961", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40961" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40961-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Thr82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003364", "url": "https://www.yeastgenome.org/locus/S000003364" }, { "database": "iPTMnet", "id": "P40961", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40961" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40961-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Thr84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003364", "url": "https://www.yeastgenome.org/locus/S000003364" }, { "database": "iPTMnet", "id": "P40961", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40961" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40961-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Val202", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "P", "comment": "Inviable.", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" }, { "database": "PubMed", "id": "31522117", "url": "https://glygen.org/publication/PubMed/31522117" } ] } ] }, { "uniprot_canonical_ac": "P40961-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Val213", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "P", "comment": "Inviable.", "evidence": [ { "database": "UniProtKB", "id": "P40961", "url": "https://www.uniprot.org/uniprotkb/P40961" }, { "database": "PubMed", "id": "31522117", "url": "https://glygen.org/publication/PubMed/31522117" } ] } ] } ], "record_id": "P40961-1" }, { "uniprot_canonical_ac": "P40988-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 552, "chemical_mass": 62792.0, "gene_names": "FET4;FET4;YM9924.11C", "protein_name": "Low-affinity Fe(2+) transport protein", "disease": [], "biological_process": [ { "name": "zinc ion transport", "id": "GO:0006829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006829", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" } ], "pmid": "" }, { "name": "iron ion transmembrane transport", "id": "GO:0034755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034755", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" } ], "pmid": "" }, { "name": "copper ion transport", "id": "GO:0006825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006825", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" } ], "pmid": "" }, { "name": "copper ion import", "id": "GO:0015677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015677", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" } ], "pmid": "" } ], "molecular_function": [ { "name": "copper ion transmembrane transporter activity", "id": "GO:0005375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005375", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" } ], "pmid": "" }, { "name": "iron ion transmembrane transporter activity", "id": "GO:0005381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005381", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40988-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Tyr29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004938", "url": "https://www.yeastgenome.org/locus/S000004938" }, { "database": "iPTMnet", "id": "P40988", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40988" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40988-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004938", "url": "https://www.yeastgenome.org/locus/S000004938" }, { "database": "iPTMnet", "id": "P40988", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40988" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40988-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40988", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40988" }, { "database": "SGD", "id": "S000004938", "url": "https://www.yeastgenome.org/locus/S000004938" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P40988-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40988", "url": "https://www.uniprot.org/uniprotkb/P40988" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P40988", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40988" }, { "database": "SGD", "id": "S000004938", "url": "https://www.yeastgenome.org/locus/S000004938" } ] } ] }, { "uniprot_canonical_ac": "P40988-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40988", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40988" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004938", "url": "https://www.yeastgenome.org/locus/S000004938" } ] } ] }, { "uniprot_canonical_ac": "P40988-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Thr54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40988", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40988" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004938", "url": "https://www.yeastgenome.org/locus/S000004938" } ] } ] } ], "record_id": "P40988-1" }, { "uniprot_canonical_ac": "P40989-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1895, "chemical_mass": 216990.0, "gene_names": "GSC2;FKS2;GLS2;GSC2", "protein_name": "1,3-beta-glucan synthase component GSC2", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "pmid": "" }, { "name": "1,3-beta-D-glucan synthase complex", "id": "GO:0000148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000148", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "pmid": "" } ], "molecular_function": [ { "name": "1,3-beta-D-glucan synthase activity", "id": "GO:0003843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003843", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "pmid": "" } ], "biological_process": [ { "name": "(1->3)-beta-D-glucan biosynthetic process", "id": "GO:0006075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006075", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "pmid": "" }, { "name": "ascospore wall assembly", "id": "GO:0030476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030476", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "pmid": "" }, { "name": "fungal-type cell wall polysaccharide biosynthetic process", "id": "GO:0051278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051278", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40989-1", "start_pos": "1540", "end_pos": "1540", "site_lbl": "Ser1540", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40989", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40989" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003264", "url": "https://www.yeastgenome.org/locus/S000003264" } ] } ] }, { "uniprot_canonical_ac": "P40989-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003264", "url": "https://www.yeastgenome.org/locus/S000003264" }, { "database": "iPTMnet", "id": "P40989", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40989" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40989-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Thr288", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ] } ] }, { "uniprot_canonical_ac": "P40989-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Thr291", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40989", "url": "https://www.uniprot.org/uniprotkb/P40989" } ] } ] }, { "uniprot_canonical_ac": "P40989-1", "start_pos": "974", "end_pos": "974", "site_lbl": "Ser974", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40989", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40989" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003264", "url": "https://www.yeastgenome.org/locus/S000003264" } ] } ] } ], "record_id": "P40989-1" }, { "uniprot_canonical_ac": "P40991-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 618, "chemical_mass": 69812.0, "gene_names": "NOP2;N2428;NOP2;YNA1;YNL2428W", "protein_name": "25S rRNA (cytosine(2870)-C(5))-methyltransferase", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1928", "name": "Williams-Beuren syndrome", "description": "A syndrome that is characterized by mild to moderate intellectual disability, a broad forehead, a short nose with a broad tip, full cheeks, and a wide mouth with full lips and difficulty with visual-spatial tasks and has_material_basis_in hemizygous deletion of 1.5 to 1.8 Mb on chromosome 7q11.23.", "url": "https://disease-ontology.org/term/DOID:1928", "evidence": [ { "id": "1928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1928" } ], "weight": 0.0 } ], "biological_process": [ { "name": "rRNA methylation", "id": "GO:0031167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031167", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" }, { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" }, { "name": "rRNA base methylation", "id": "GO:0070475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070475", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" }, { "name": "assembly of large subunit precursor of preribosome", "id": "GO:1902626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902626", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" } ], "molecular_function": [ { "name": "rRNA (cytosine-C5-)-methyltransferase activity", "id": "GO:0009383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009383", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40991-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Thr319", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 319, "start_aa": "Thr", "end_pos": 319, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr319", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Thr183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40991", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40991" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005005", "url": "https://www.yeastgenome.org/locus/S000005005" }, { "database": "iPTMnet", "id": "P40991", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Ser385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005005", "url": "https://www.yeastgenome.org/locus/S000005005" }, { "database": "iPTMnet", "id": "P40991", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40991" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005005", "url": "https://www.yeastgenome.org/locus/S000005005" }, { "database": "iPTMnet", "id": "P40991", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005005", "url": "https://www.yeastgenome.org/locus/S000005005" }, { "database": "iPTMnet", "id": "P40991", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40991" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Ser515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005005", "url": "https://www.yeastgenome.org/locus/S000005005" }, { "database": "iPTMnet", "id": "P40991", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40991" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Ser553", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005005", "url": "https://www.yeastgenome.org/locus/S000005005" }, { "database": "iPTMnet", "id": "P40991", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40991" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "580", "end_pos": "580", "site_lbl": "Ser580", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P40991", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40991" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005005", "url": "https://www.yeastgenome.org/locus/S000005005" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "615", "end_pos": "615", "site_lbl": "Ser615", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005005", "url": "https://www.yeastgenome.org/locus/S000005005" }, { "database": "iPTMnet", "id": "P40991", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40991" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Cys424", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Cannot complement loss of wild type NOP2.", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" }, { "database": "PubMed", "id": "9854021", "url": "https://glygen.org/publication/PubMed/9854021" }, { "database": "PubMed", "id": "23913415", "url": "https://glygen.org/publication/PubMed/23913415" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Cannot complement loss of wild type NOP2.", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" }, { "database": "PubMed", "id": "9854021", "url": "https://glygen.org/publication/PubMed/9854021" }, { "database": "PubMed", "id": "23913415", "url": "https://glygen.org/publication/PubMed/23913415" } ] } ] }, { "uniprot_canonical_ac": "P40991-1", "start_pos": "478", "end_pos": "478", "site_lbl": "Cys478", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Fails to ctalyze the C-5 methylation of the C2870 residue and strongly affects 60S biogenesis.", "evidence": [ { "database": "UniProtKB", "id": "P40991", "url": "https://www.uniprot.org/uniprotkb/P40991" }, { "database": "PubMed", "id": "9854021", "url": "https://glygen.org/publication/PubMed/9854021" }, { "database": "PubMed", "id": "23913415", "url": "https://glygen.org/publication/PubMed/23913415" } ] } ] } ], "record_id": "P40991-1" }, { "uniprot_canonical_ac": "P40992-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40992", "url": "https://www.uniprot.org/uniprotkb/P40992" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 514, "chemical_mass": 60357.0, "gene_names": "RRN7;J1273;RRN7", "protein_name": "RNA polymerase I-specific transcription initiation factor RRN7", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P40992", "url": "https://www.uniprot.org/uniprotkb/P40992" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P40992", "url": "https://www.uniprot.org/uniprotkb/P40992" } ], "pmid": "" }, { "name": "RNA polymerase I core factor complex", "id": "GO:0070860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070860", "evidence": [ { "database": "UniProtKB", "id": "P40992", "url": "https://www.uniprot.org/uniprotkb/P40992" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P40992", "url": "https://www.uniprot.org/uniprotkb/P40992" } ], "pmid": "" }, { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "P40992", "url": "https://www.uniprot.org/uniprotkb/P40992" } ], "pmid": "" }, { "name": "RNA polymerase I core promoter sequence-specific DNA binding", "id": "GO:0001164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001164", "evidence": [ { "database": "UniProtKB", "id": "P40992", "url": "https://www.uniprot.org/uniprotkb/P40992" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleolar large rRNA transcription by RNA polymerase I", "id": "GO:0042790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042790", "evidence": [ { "database": "UniProtKB", "id": "P40992", "url": "https://www.uniprot.org/uniprotkb/P40992" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40992-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Cys29", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Impaired binding to Pol I.", "evidence": [ { "database": "UniProtKB", "id": "P40992", "url": "https://www.uniprot.org/uniprotkb/P40992" }, { "database": "PubMed", "id": "21921198", "url": "https://glygen.org/publication/PubMed/21921198" } ] } ] }, { "uniprot_canonical_ac": "P40992-1", "start_pos": "33", "end_pos": "33", "site_lbl": "His33", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "S", "comment": "Impaired binding to Pol I.", "evidence": [ { "database": "UniProtKB", "id": "P40992", "url": "https://www.uniprot.org/uniprotkb/P40992" }, { "database": "PubMed", "id": "21921198", "url": "https://glygen.org/publication/PubMed/21921198" } ] } ] } ], "record_id": "P40992-1" }, { "uniprot_canonical_ac": "P40993-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 198, "chemical_mass": 22541.0, "gene_names": "SNM1;D8035.21;SNM1", "protein_name": "Ribonuclease MRP protein subunit SNM1", "disease": [], "cellular_component": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "pmid": "" }, { "name": "plasmid partitioning", "id": "GO:0030541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030541", "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "pmid": "" }, { "name": "nuclease activity", "id": "GO:0004518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004518", "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "pmid": "" }, { "name": "rRNA primary transcript binding", "id": "GO:0042134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042134", "evidence": [ { "database": "UniProtKB", "id": "P40993", "url": "https://www.uniprot.org/uniprotkb/P40993" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P40993-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40993", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40993" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002886", "url": "https://www.yeastgenome.org/locus/S000002886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40993-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P40993", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40993" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002886", "url": "https://www.yeastgenome.org/locus/S000002886" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P40993-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002886", "url": "https://www.yeastgenome.org/locus/S000002886" }, { "database": "iPTMnet", "id": "P40993", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40993" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P40993-1" }, { "uniprot_canonical_ac": "P41056-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41056", "url": "https://www.uniprot.org/uniprotkb/P41056" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 107, "chemical_mass": 12168.0, "gene_names": "RPL33B;O5224;RPL33B;RPL37B", "protein_name": "Large ribosomal subunit protein eL33B", "disease": [ { "disease_id": "DOID:0111883", "name": "Diamond-Blackfan anemia 5", "description": "A Diamond-Blackfan anemia that has_material_basis_in heterozygous mutation in the RPL35A gene on chromosome 3q29.", "url": "https://disease-ontology.org/term/DOID:0111883", "evidence": [ { "id": "0111883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111883" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P41056", "url": "https://www.uniprot.org/uniprotkb/P41056" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P41056", "url": "https://www.uniprot.org/uniprotkb/P41056" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P41056", "url": "https://www.uniprot.org/uniprotkb/P41056" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P41056", "url": "https://www.uniprot.org/uniprotkb/P41056" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P41056", "url": "https://www.uniprot.org/uniprotkb/P41056" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41056-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Thr37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005760", "url": "https://www.yeastgenome.org/locus/S000005760" }, { "database": "iPTMnet", "id": "P41056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41056" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41056-1" }, { "uniprot_canonical_ac": "P41277-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41277", "url": "https://www.uniprot.org/uniprotkb/P41277" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 250, "chemical_mass": 27947.0, "gene_names": "GPP1;GPP1;RHR2", "protein_name": "Glycerol-1-phosphate phosphohydrolase 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P41277", "url": "https://www.uniprot.org/uniprotkb/P41277" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P41277", "url": "https://www.uniprot.org/uniprotkb/P41277" } ], "pmid": "" } ], "biological_process": [ { "name": "response to osmotic stress", "id": "GO:0006970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006970", "evidence": [ { "database": "UniProtKB", "id": "P41277", "url": "https://www.uniprot.org/uniprotkb/P41277" } ], "pmid": "" }, { "name": "glycerol biosynthetic process", "id": "GO:0006114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006114", "evidence": [ { "database": "UniProtKB", "id": "P41277", "url": "https://www.uniprot.org/uniprotkb/P41277" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P41277", "url": "https://www.uniprot.org/uniprotkb/P41277" } ], "pmid": "" }, { "name": "sn-glycerol 1-phosphatase activity", "id": "GO:0000121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000121", "evidence": [ { "database": "UniProtKB", "id": "P41277", "url": "https://www.uniprot.org/uniprotkb/P41277" } ], "pmid": "" }, { "name": "sn-glycerol 3-phosphatase activity", "id": "GO:0043136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043136", "evidence": [ { "database": "UniProtKB", "id": "P41277", "url": "https://www.uniprot.org/uniprotkb/P41277" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41277-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Thr115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41277", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41277" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P41277-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41277", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41277" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001315", "url": "https://www.yeastgenome.org/locus/S000001315" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41277-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Thr118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001315", "url": "https://www.yeastgenome.org/locus/S000001315" }, { "database": "iPTMnet", "id": "P41277", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41277" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P41277-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Ser170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001315", "url": "https://www.yeastgenome.org/locus/S000001315" }, { "database": "iPTMnet", "id": "P41277", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41277" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41277-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001315", "url": "https://www.yeastgenome.org/locus/S000001315" }, { "database": "iPTMnet", "id": "P41277", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41277" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41277-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41277", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41277" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000001315", "url": "https://www.yeastgenome.org/locus/S000001315" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41277-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001315", "url": "https://www.yeastgenome.org/locus/S000001315" }, { "database": "iPTMnet", "id": "P41277", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41277" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41277-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Tyr86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001315", "url": "https://www.yeastgenome.org/locus/S000001315" }, { "database": "iPTMnet", "id": "P41277", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41277" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41277-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41277", "url": "https://www.uniprot.org/uniprotkb/P41277" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P41277", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41277" }, { "database": "SGD", "id": "S000001315", "url": "https://www.yeastgenome.org/locus/S000001315" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41277-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41277", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41277" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001315", "url": "https://www.yeastgenome.org/locus/S000001315" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41277-1" }, { "uniprot_canonical_ac": "P41338-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41338", "url": "https://www.uniprot.org/uniprotkb/P41338" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 398, "chemical_mass": 41729.0, "gene_names": "ERG10;ERG10;LPB3;TSM0115", "protein_name": "Acetyl-CoA acetyltransferase", "disease": [ { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:14723", "name": "beta-ketothiolase deficiency", "description": "An amino acid metabolic disorder characterized by inability to process isoleucine and ketones, has_symptom recurrent ketoacidotic attacks in infancy marked by vomiting, lethargy, dehydration, and seizures, and has_material_basis_in mutation in the ACAT1 gene of chromosome 11q22.3 responsible for producing the ACAT1 enzyme in mitochondria, which processes isoleucine and ketones.", "url": "https://disease-ontology.org/term/DOID:14723", "evidence": [ { "id": "14723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14723" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2978", "name": "carbohydrate metabolic disorder", "description": "An inherited metabolic disorder that affect the catabolism and anabolism of carbohydrates.", "url": "https://disease-ontology.org/term/DOID:2978", "evidence": [ { "id": "2978", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2978" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ergosterol biosynthetic process", "id": "GO:0006696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006696", "evidence": [ { "database": "UniProtKB", "id": "P41338", "url": "https://www.uniprot.org/uniprotkb/P41338" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P41338", "url": "https://www.uniprot.org/uniprotkb/P41338" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P41338", "url": "https://www.uniprot.org/uniprotkb/P41338" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P41338", "url": "https://www.uniprot.org/uniprotkb/P41338" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P41338", "url": "https://www.uniprot.org/uniprotkb/P41338" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "P41338", "url": "https://www.uniprot.org/uniprotkb/P41338" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P41338", "url": "https://www.uniprot.org/uniprotkb/P41338" } ], "pmid": "" }, { "name": "acetyl-CoA C-acetyltransferase activity", "id": "GO:0003985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003985", "evidence": [ { "database": "UniProtKB", "id": "P41338", "url": "https://www.uniprot.org/uniprotkb/P41338" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41338-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005949", "url": "https://www.yeastgenome.org/locus/S000005949" }, { "database": "iPTMnet", "id": "P41338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41338-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Thr13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005949", "url": "https://www.yeastgenome.org/locus/S000005949" }, { "database": "iPTMnet", "id": "P41338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41338-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005949", "url": "https://www.yeastgenome.org/locus/S000005949" }, { "database": "iPTMnet", "id": "P41338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41338-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005949", "url": "https://www.yeastgenome.org/locus/S000005949" }, { "database": "iPTMnet", "id": "P41338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41338-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Thr206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005949", "url": "https://www.yeastgenome.org/locus/S000005949" }, { "database": "iPTMnet", "id": "P41338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41338-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005949", "url": "https://www.yeastgenome.org/locus/S000005949" }, { "database": "iPTMnet", "id": "P41338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41338" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41338-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005949", "url": "https://www.yeastgenome.org/locus/S000005949" }, { "database": "iPTMnet", "id": "P41338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41338" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41338-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41338" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005949", "url": "https://www.yeastgenome.org/locus/S000005949" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41338-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Thr26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005949", "url": "https://www.yeastgenome.org/locus/S000005949" }, { "database": "iPTMnet", "id": "P41338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41338-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005949", "url": "https://www.yeastgenome.org/locus/S000005949" }, { "database": "iPTMnet", "id": "P41338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P41338-1" }, { "uniprot_canonical_ac": "P41546-2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41546", "url": "https://www.uniprot.org/uniprotkb/P41546" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 238, "chemical_mass": 26905.0, "gene_names": "HAC1;ERN4;HAC1;IRE15;IRE2", "protein_name": "Transcriptional activator HAC1", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P41546", "url": "https://www.uniprot.org/uniprotkb/P41546" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P41546", "url": "https://www.uniprot.org/uniprotkb/P41546" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P41546", "url": "https://www.uniprot.org/uniprotkb/P41546" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "P41546", "url": "https://www.uniprot.org/uniprotkb/P41546" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "P41546", "url": "https://www.uniprot.org/uniprotkb/P41546" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P41546", "url": "https://www.uniprot.org/uniprotkb/P41546" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P41546", "url": "https://www.uniprot.org/uniprotkb/P41546" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P41546", "url": "https://www.uniprot.org/uniprotkb/P41546" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P41546", "url": "https://www.uniprot.org/uniprotkb/P41546" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41546-2", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001863", "url": "https://www.yeastgenome.org/locus/S000001863" }, { "database": "iPTMnet", "id": "P41546", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41546" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41546-2", "start_pos": "144", "end_pos": "144", "site_lbl": "Thr144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001863", "url": "https://www.yeastgenome.org/locus/S000001863" }, { "database": "iPTMnet", "id": "P41546", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41546" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41546-2", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001863", "url": "https://www.yeastgenome.org/locus/S000001863" }, { "database": "iPTMnet", "id": "P41546", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41546" }, { "database": "PubMed", "id": "17108329", "url": "https://glygen.org/publication/PubMed/17108329" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41546-2", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001863", "url": "https://www.yeastgenome.org/locus/S000001863" }, { "database": "iPTMnet", "id": "P41546", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41546" }, { "database": "PubMed", "id": "17108329", "url": "https://glygen.org/publication/PubMed/17108329" } ] } ] }, { "uniprot_canonical_ac": "P41546-2", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001863", "url": "https://www.yeastgenome.org/locus/S000001863" }, { "database": "iPTMnet", "id": "P41546", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41546" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41546-2", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001863", "url": "https://www.yeastgenome.org/locus/S000001863" }, { "database": "iPTMnet", "id": "P41546", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41546" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41546-2" }, { "uniprot_canonical_ac": "P41697-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 788, "chemical_mass": 88817.0, "gene_names": "BUD6;AIP3;BUD6;L8543.5", "protein_name": "Bud site selection protein 6", "disease": [], "cellular_component": [ { "name": "secretory vesicle", "id": "GO:0099503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099503", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "cell tip", "id": "GO:0051286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051286", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "polarisome", "id": "GO:0000133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000133", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "cytoskeletal regulatory protein binding", "id": "GO:0005519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005519", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "actin nucleation", "id": "GO:0045010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045010", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "positive regulation of actin nucleation", "id": "GO:0051127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051127", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "cellular hyperosmotic response", "id": "GO:0071474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071474", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "vesicle targeting", "id": "GO:0006903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006903", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "establishment or maintenance of actin cytoskeleton polarity", "id": "GO:0030950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030950", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "astral microtubule organization", "id": "GO:0030953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030953", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "budding cell apical bud growth", "id": "GO:0007118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007118", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "bipolar cellular bud site selection", "id": "GO:0007121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007121", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "pseudohyphal growth", "id": "GO:0007124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007124", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" }, { "name": "positive regulation of formin-nucleated actin cable assembly", "id": "GO:0090338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090338", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41697-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Thr203", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 203, "start_aa": "Thr", "end_pos": 203, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr203", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Tyr10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Thr12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Ser143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Thr155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ser159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Ser162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Thr165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Thr169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Ser173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Thr18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Ser208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Ser240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Thr281", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Ser283", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Ser296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Ser324", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Ser327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "20020052", "url": "https://glygen.org/publication/PubMed/20020052" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Thr332", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "342", "end_pos": "342", "site_lbl": "Ser342", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41697", "url": "https://www.uniprot.org/uniprotkb/P41697" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "20020052", "url": "https://glygen.org/publication/PubMed/20020052" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Ser347", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Ser348", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Thr351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Thr352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "687", "end_pos": "687", "site_lbl": "Ser687", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "689", "end_pos": "689", "site_lbl": "Ser689", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "700", "end_pos": "700", "site_lbl": "Thr700", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41697-1", "start_pos": "761", "end_pos": "761", "site_lbl": "Ser761", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004311", "url": "https://www.yeastgenome.org/locus/S000004311" }, { "database": "iPTMnet", "id": "P41697", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41697" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41697-1" }, { "uniprot_canonical_ac": "P41735-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 233, "chemical_mass": 26060.0, "gene_names": "CAT5;CAT5;COQ7;O3284;YOR3284C", "protein_name": "5-demethoxyubiquinone hydroxylase, mitochondrial", "disease": [ { "disease_id": "DOID:0070245", "name": "primary coenzyme Q10 deficiency 8", "description": "A primary coenzyme Q10 deficiency that has_material_basis_in an autosomal recessive mutation of the COQ7 gene on chromosome 16p12.3.", "url": "https://disease-ontology.org/term/DOID:0070245", "evidence": [ { "id": "0070245", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070245" } ], "weight": 0.0 }, { "disease_id": "DOID:0081428", "name": "autosomal recessive distal hereditary motor neuronopathy 9", "description": "An autosomal recessive distal hereditary motor neuronopathy characterized by juvenile onset of distal muscle weakness and atrophy, resulting in gait difficulties and that has_material_basis_in homozygous or compound heterozygous mutation in the COQ7 gene on chromosome 16p12.", "url": "https://disease-ontology.org/term/DOID:0081428", "evidence": [ { "id": "0081428", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081428" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" } ], "pmid": "" }, { "name": "3-demethoxyubiquinol 3-hydroxylase activity", "id": "GO:0008682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008682", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" } ], "pmid": "" }, { "name": "3-demethoxyubiquinone 3-hydroxylase (NADH) activity", "id": "GO:0160224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160224", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" } ], "pmid": "" } ], "biological_process": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41735-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005651", "url": "https://www.yeastgenome.org/locus/S000005651" }, { "database": "iPTMnet", "id": "P41735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41735" }, { "database": "PubMed", "id": "26497406", "url": "https://glygen.org/publication/PubMed/26497406" } ] } ] }, { "uniprot_canonical_ac": "P41735-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" }, { "database": "PubMed", "id": "23940037", "url": "https://glygen.org/publication/PubMed/23940037" }, { "database": "SGD", "id": "S000005651", "url": "https://www.yeastgenome.org/locus/S000005651" }, { "database": "iPTMnet", "id": "P41735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41735" }, { "database": "PubMed", "id": "21812761", "url": "https://glygen.org/publication/PubMed/21812761" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of phosphorylation and increased levels of COQ6; when associated with S-28 and T-32.", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" }, { "database": "PubMed", "id": "23940037", "url": "https://glygen.org/publication/PubMed/23940037" } ] } ] }, { "uniprot_canonical_ac": "P41735-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" }, { "database": "PubMed", "id": "23940037", "url": "https://glygen.org/publication/PubMed/23940037" }, { "database": "SGD", "id": "S000005651", "url": "https://www.yeastgenome.org/locus/S000005651" }, { "database": "iPTMnet", "id": "P41735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41735" }, { "database": "PubMed", "id": "21812761", "url": "https://glygen.org/publication/PubMed/21812761" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of phosphorylation and increased levels of COQ6; when associated with S-20 and T-32.", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" }, { "database": "PubMed", "id": "23940037", "url": "https://glygen.org/publication/PubMed/23940037" } ] } ] }, { "uniprot_canonical_ac": "P41735-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Thr32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" }, { "database": "PubMed", "id": "23940037", "url": "https://glygen.org/publication/PubMed/23940037" }, { "database": "SGD", "id": "S000005651", "url": "https://www.yeastgenome.org/locus/S000005651" }, { "database": "iPTMnet", "id": "P41735", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41735" }, { "database": "PubMed", "id": "21812761", "url": "https://glygen.org/publication/PubMed/21812761" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Loss of phosphorylation and increased levels of COQ6; when associated with S-20 and S-28.", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" }, { "database": "PubMed", "id": "23940037", "url": "https://glygen.org/publication/PubMed/23940037" } ] } ] }, { "uniprot_canonical_ac": "P41735-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Glu194", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Lacks ubiquinone and accumulates the intermediate DMQH2, causing respiratory deficiency.", "evidence": [ { "database": "UniProtKB", "id": "P41735", "url": "https://www.uniprot.org/uniprotkb/P41735" }, { "database": "PubMed", "id": "16624818", "url": "https://glygen.org/publication/PubMed/16624818" } ] } ] } ], "record_id": "P41735-1" }, { "uniprot_canonical_ac": "P41800-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 426, "chemical_mass": 48660.0, "gene_names": "MMM1;L1357;MMM1;YME6", "protein_name": "Maintenance of mitochondrial morphology protein 1", "disease": [], "biological_process": [ { "name": "protein insertion into mitochondrial outer membrane", "id": "GO:0045040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045040", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "intermembrane lipid transfer", "id": "GO:0120009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120009", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "aminophospholipid transport", "id": "GO:0015917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015917", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "mitochondrial outer membrane translocase complex assembly", "id": "GO:0070096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070096", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "mitochondrion-endoplasmic reticulum membrane tethering", "id": "GO:1990456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990456", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" }, { "name": "ERMES complex", "id": "GO:0032865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032865", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41800-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Asn50", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 50, "start_aa": "Asn", "end_pos": 50, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn50", "evidence": [ { "id": "P41800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41800#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P41800-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Asn55", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 55, "start_aa": "Asn", "end_pos": 55, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn55", "evidence": [ { "id": "P41800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41800#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P41800-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Asn59", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 59, "start_aa": "Asn", "end_pos": 59, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn59", "evidence": [ { "id": "P41800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41800#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P41800-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Asn6", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 6, "start_aa": "Asn", "end_pos": 6, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn6", "evidence": [ { "id": "P41800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41800#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P41800-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Glu215", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "In MMM1-6; impairs both mtDNA maintenance and mitochondrial morpholgy.", "evidence": [ { "database": "UniProtKB", "id": "P41800", "url": "https://www.uniprot.org/uniprotkb/P41800" }, { "database": "PubMed", "id": "12454062", "url": "https://glygen.org/publication/PubMed/12454062" } ] } ] } ], "record_id": "P41800-1" }, { "uniprot_canonical_ac": "P41805-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 221, "chemical_mass": 25361.0, "gene_names": "RPL10;GRC5;QSR1;RPL10", "protein_name": "Large ribosomal subunit protein uL16", "disease": [ { "disease_id": "DOID:0060807", "name": "syndromic X-linked intellectual disability Najm type", "description": "A syndromic X-linked intellectual disability characterized by severe intellectual disability, microcephaly with pontine and cerebellar hypoplasia that has_material_basis_in heterozygous mutation or deletion in the CASK gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0060807", "evidence": [ { "id": "0060807", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060807" } ], "weight": 0.0 }, { "disease_id": "DOID:0080241", "name": "syndromic X-linked mental retardation 35", "description": "A syndromic X-linked intellectual disability that has_material_basis_in mutation in the RPL10 gene on chromosome Xq28.", "url": "https://disease-ontology.org/term/DOID:0080241", "evidence": [ { "id": "0080241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080241" } ], "weight": 0.0 }, { "disease_id": "DOID:0112356", "name": "spermatogenic failure 63", "description": "A spermatogenic failure characterized by male infertility due to severe oligozoospermia with markedly reduced progressive sperm motility that has_material_basis_in homozygous or compound heterozygous mutation in the RPL10L gene on chromosome 14q21.2.", "url": "https://disease-ontology.org/term/DOID:0112356", "evidence": [ { "id": "0112356", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112356" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:14789", "name": "spondyloepiphyseal dysplasia congenita", "description": "A spondyloepiphyseal dysplasia characterized by disproportionate short stature (short trunk), abnormal epiphyses, and flattened vertebral bodies that has_material_basis_in heterozygous mutation in the COL2A1 gene on chromosome 12q13.11.", "url": "https://disease-ontology.org/term/DOID:14789", "evidence": [ { "id": "14789", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14789" } ], "weight": 0.0 }, { "disease_id": "DOID:5603", "name": "T-cell acute lymphoblastic leukemia", "description": "An acute lymphoblastic leukemia that is characterized by too many T-cell lymphoblasts found in the bone marrow and blood.", "url": "https://disease-ontology.org/term/DOID:5603", "evidence": [ { "id": "5603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5603" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" } ], "pmid": "" } ], "biological_process": [ { "name": "translational termination", "id": "GO:0006415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006415", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41805-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004065", "url": "https://www.yeastgenome.org/locus/S000004065" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41805-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Ser143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P41805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41805" }, { "database": "SGD", "id": "S000004065", "url": "https://www.yeastgenome.org/locus/S000004065" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41805-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P41805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41805" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004065", "url": "https://www.yeastgenome.org/locus/S000004065" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41805-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004065", "url": "https://www.yeastgenome.org/locus/S000004065" }, { "database": "iPTMnet", "id": "P41805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41805" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41805-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Tyr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004065", "url": "https://www.yeastgenome.org/locus/S000004065" }, { "database": "iPTMnet", "id": "P41805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41805-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Thr78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004065", "url": "https://www.yeastgenome.org/locus/S000004065" }, { "database": "iPTMnet", "id": "P41805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41805" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41805-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004065", "url": "https://www.yeastgenome.org/locus/S000004065" }, { "database": "iPTMnet", "id": "P41805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41805-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Gly194", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In QSR1-1; synthetic lethal.", "evidence": [ { "database": "UniProtKB", "id": "P41805", "url": "https://www.uniprot.org/uniprotkb/P41805" }, { "database": "PubMed", "id": "7730379", "url": "https://glygen.org/publication/PubMed/7730379" } ] } ] } ], "record_id": "P41805-1" }, { "uniprot_canonical_ac": "P41809-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1802, "chemical_mass": 188948.0, "gene_names": "HKR1;HKR1", "protein_name": "Signaling mucin HKR1", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" }, { "name": "site of polarized growth", "id": "GO:0030427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030427", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" } ], "biological_process": [ { "name": "hyperosmotic response", "id": "GO:0006972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006972", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" }, { "name": "cellular bud site selection", "id": "GO:0000282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000282", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" }, { "name": "signal transduction involved in filamentous growth", "id": "GO:0001402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001402", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" }, { "name": "(1->3)-beta-D-glucan biosynthetic process", "id": "GO:0006075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006075", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" }, { "name": "osmosensory signaling pathway via Sho1 osmosensor", "id": "GO:0007232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007232", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" } ], "molecular_function": [ { "name": "osmosensor activity", "id": "GO:0005034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005034", "evidence": [ { "database": "UniProtKB", "id": "P41809", "url": "https://www.uniprot.org/uniprotkb/P41809" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41809-1", "start_pos": "1225", "end_pos": "1225", "site_lbl": "Thr1225", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1225, "start_aa": "Thr", "end_pos": 1225, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1225", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "1252", "end_pos": "1252", "site_lbl": "Asn1252", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1252, "start_aa": "Asn", "end_pos": 1252, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1252", "evidence": [ { "id": "P41809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41809#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "1293", "end_pos": "1293", "site_lbl": "Asn1293", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1293, "start_aa": "Asn", "end_pos": 1293, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1293", "evidence": [ { "id": "P41809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41809#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "1342", "end_pos": "1342", "site_lbl": "Asn1342", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1342, "start_aa": "Asn", "end_pos": 1342, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1342", "evidence": [ { "id": "P41809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41809#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "1400", "end_pos": "1400", "site_lbl": "Asn1400", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1400, "start_aa": "Asn", "end_pos": 1400, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1400", "evidence": [ { "id": "P41809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41809#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Asn24", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 24, "start_aa": "Asn", "end_pos": 24, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn24", "evidence": [ { "id": "P41809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41809#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Thr39", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "1535", "end_pos": "1535", "site_lbl": "Ser1535", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002828", "url": "https://www.yeastgenome.org/locus/S000002828" }, { "database": "iPTMnet", "id": "P41809", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41809" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "1539", "end_pos": "1539", "site_lbl": "Ser1539", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002828", "url": "https://www.yeastgenome.org/locus/S000002828" }, { "database": "iPTMnet", "id": "P41809", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41809" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "1555", "end_pos": "1555", "site_lbl": "Ser1555", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002828", "url": "https://www.yeastgenome.org/locus/S000002828" }, { "database": "iPTMnet", "id": "P41809", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41809" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "1612", "end_pos": "1612", "site_lbl": "Ser1612", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002828", "url": "https://www.yeastgenome.org/locus/S000002828" }, { "database": "iPTMnet", "id": "P41809", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41809" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "1616", "end_pos": "1616", "site_lbl": "Ser1616", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002828", "url": "https://www.yeastgenome.org/locus/S000002828" }, { "database": "iPTMnet", "id": "P41809", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41809" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41809-1", "start_pos": "961", "end_pos": "961", "site_lbl": "Ser961", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002828", "url": "https://www.yeastgenome.org/locus/S000002828" }, { "database": "iPTMnet", "id": "P41809", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41809" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41809-1" }, { "uniprot_canonical_ac": "P41810-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 973, "chemical_mass": 109019.0, "gene_names": "SEC26;SEC26;YD8419.05C", "protein_name": "Coatomer subunit beta", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" } ], "pmid": "" }, { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41810-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41810-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Ser483", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41810-1", "start_pos": "540", "end_pos": "540", "site_lbl": "Ser540", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41810", "url": "https://www.uniprot.org/uniprotkb/P41810" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41810-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Thr542", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41810-1", "start_pos": "677", "end_pos": "677", "site_lbl": "Ser677", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41810-1", "start_pos": "686", "end_pos": "686", "site_lbl": "Thr686", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41810-1", "start_pos": "689", "end_pos": "689", "site_lbl": "Ser689", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41810-1", "start_pos": "723", "end_pos": "723", "site_lbl": "Ser723", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41810-1", "start_pos": "895", "end_pos": "895", "site_lbl": "Thr895", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41810-1", "start_pos": "897", "end_pos": "897", "site_lbl": "Ser897", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41810-1", "start_pos": "899", "end_pos": "899", "site_lbl": "Ser899", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002646", "url": "https://www.yeastgenome.org/locus/S000002646" }, { "database": "iPTMnet", "id": "P41810", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41810" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41810-1" }, { "uniprot_canonical_ac": "P41812-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 875, "chemical_mass": 100395.0, "gene_names": "POP1;N1285;POP1", "protein_name": "Ribonucleases P/MRP protein subunit POP1", "disease": [ { "disease_id": "DOID:0080962", "name": "anauxetic dysplasia 2", "description": "A spondyloepimetaphyseal dysplasia that is has_material_basis_in homozygous or compound heterozygous mutation in the POP1 gene on chromosome 8q22.", "url": "https://disease-ontology.org/term/DOID:0080962", "evidence": [ { "id": "0080962", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080962" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" }, { "name": "telomerase holoenzyme complex", "id": "GO:0005697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005697", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, RNase MRP-dependent", "id": "GO:0000294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000294", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" }, { "name": "intronic box C/D snoRNA processing", "id": "GO:0034965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034965", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" }, { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41812-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005165", "url": "https://www.yeastgenome.org/locus/S000005165" }, { "database": "iPTMnet", "id": "P41812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41812" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P41812-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Thr175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005165", "url": "https://www.yeastgenome.org/locus/S000005165" }, { "database": "iPTMnet", "id": "P41812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41812" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P41812-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Thr46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005165", "url": "https://www.yeastgenome.org/locus/S000005165" }, { "database": "iPTMnet", "id": "P41812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41812" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41812-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005165", "url": "https://www.yeastgenome.org/locus/S000005165" }, { "database": "iPTMnet", "id": "P41812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41812" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41812-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Tyr518", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005165", "url": "https://www.yeastgenome.org/locus/S000005165" }, { "database": "iPTMnet", "id": "P41812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41812" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41812-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005165", "url": "https://www.yeastgenome.org/locus/S000005165" }, { "database": "iPTMnet", "id": "P41812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41812" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41812-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Thr522", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41812" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P41812-1", "start_pos": "524", "end_pos": "524", "site_lbl": "Thr524", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41812", "url": "https://www.uniprot.org/uniprotkb/P41812" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P41812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41812" }, { "database": "SGD", "id": "S000005165", "url": "https://www.yeastgenome.org/locus/S000005165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41812-1" }, { "uniprot_canonical_ac": "P41816-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41816", "url": "https://www.uniprot.org/uniprotkb/P41816" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 400, "chemical_mass": 44920.0, "gene_names": "OYE3;OYE3;P2291;ZRG6", "protein_name": "NADPH dehydrogenase 3", "disease": [], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "P41816", "url": "https://www.uniprot.org/uniprotkb/P41816" } ], "pmid": "" } ], "molecular_function": [ { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "P41816", "url": "https://www.uniprot.org/uniprotkb/P41816" } ], "pmid": "" }, { "name": "NADPH dehydrogenase activity", "id": "GO:0003959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003959", "evidence": [ { "database": "UniProtKB", "id": "P41816", "url": "https://www.uniprot.org/uniprotkb/P41816" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41816-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006092", "url": "https://www.yeastgenome.org/locus/S000006092" }, { "database": "iPTMnet", "id": "P41816", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41816" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41816-1" }, { "uniprot_canonical_ac": "P41821-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 548, "chemical_mass": 61575.0, "gene_names": "MID1;MID1;N0530", "protein_name": "Stretch-activated cation channel MID1", "disease": [], "molecular_function": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" } ], "pmid": "" }, { "name": "stretch-activated, monoatomic cation-selective, calcium channel activity", "id": "GO:0015275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015275", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" } ], "pmid": "" }, { "name": "calcium ion import across plasma membrane", "id": "GO:0098703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098703", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41821-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Asn112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 112, "start_aa": "Asn", "end_pos": 112, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn112", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Asn125", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 125, "start_aa": "Asn", "end_pos": 125, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn125", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Asn159", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 159, "start_aa": "Asn", "end_pos": 159, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn159", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Asn175", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 175, "start_aa": "Asn", "end_pos": 175, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn175", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Asn228", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 228, "start_aa": "Asn", "end_pos": 228, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn228", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Asn238", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 238, "start_aa": "Asn", "end_pos": 238, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn238", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Asn265", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 265, "start_aa": "Asn", "end_pos": 265, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn265", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Asn282", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 282, "start_aa": "Asn", "end_pos": 282, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn282", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Asn285", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 285, "start_aa": "Asn", "end_pos": 285, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn285", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Asn291", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 291, "start_aa": "Asn", "end_pos": 291, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn291", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Asn324", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 324, "start_aa": "Asn", "end_pos": 324, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn324", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Asn32", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 32, "start_aa": "Asn", "end_pos": 32, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn32", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Asn70", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 70, "start_aa": "Asn", "end_pos": 70, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "P41821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41821#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Phe356", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Significantly low viability and relatively normal Ca(2+) accumulation.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "14697255", "url": "https://glygen.org/publication/PubMed/14697255" } ] }, { "sequence_org": "F", "sequence_mut": "D", "comment": "Substitution by hydrophilic amino acids causes lethality and low Ca(2+) accumulation.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "14697255", "url": "https://glygen.org/publication/PubMed/14697255" } ] }, { "sequence_org": "F", "sequence_mut": "E", "comment": "Substitution by hydrophilic amino acids causes lethality and low Ca(2+) accumulation.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "14697255", "url": "https://glygen.org/publication/PubMed/14697255" } ] }, { "sequence_org": "F", "sequence_mut": "H", "comment": "Substitution by hydrophilic amino acids causes lethality and low Ca(2+) accumulation.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "14697255", "url": "https://glygen.org/publication/PubMed/14697255" } ] }, { "sequence_org": "F", "sequence_mut": "K", "comment": "Substitution by hydrophilic amino acids causes lethality and low Ca(2+) accumulation.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "14697255", "url": "https://glygen.org/publication/PubMed/14697255" } ] }, { "sequence_org": "F", "sequence_mut": "L", "comment": "Substitution by hydrophobic, large amino acids does not cause lethality nor low Ca(2+) accumulation.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "14697255", "url": "https://glygen.org/publication/PubMed/14697255" } ] }, { "sequence_org": "F", "sequence_mut": "Q", "comment": "Substitution by hydrophilic amino acids causes lethality and low Ca(2+) accumulation.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "14697255", "url": "https://glygen.org/publication/PubMed/14697255" } ] }, { "sequence_org": "F", "sequence_mut": "R", "comment": "Substitution by hydrophilic amino acids causes lethality and low Ca(2+) accumulation.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "14697255", "url": "https://glygen.org/publication/PubMed/14697255" } ] }, { "sequence_org": "F", "sequence_mut": "W", "comment": "Substitution by hydrophobic, large amino acids does not cause lethality nor low Ca(2+) accumulation.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "14697255", "url": "https://glygen.org/publication/PubMed/14697255" } ] }, { "sequence_org": "F", "sequence_mut": "Y", "comment": "Substitution by hydrophobic, large amino acids does not cause lethality nor low Ca(2+) accumulation.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "14697255", "url": "https://glygen.org/publication/PubMed/14697255" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Cys417", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Non-functional.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "11796727", "url": "https://glygen.org/publication/PubMed/11796727" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Cys431", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Non-functional.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "11796727", "url": "https://glygen.org/publication/PubMed/11796727" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Cys434", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Non-functional.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "11796727", "url": "https://glygen.org/publication/PubMed/11796727" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "491", "end_pos": "491", "site_lbl": "Cys491", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Functionally impaired.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "11796727", "url": "https://glygen.org/publication/PubMed/11796727" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Cys498", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Non-functional.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "11796727", "url": "https://glygen.org/publication/PubMed/11796727" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Cys506", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Functionally impaired.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "11796727", "url": "https://glygen.org/publication/PubMed/11796727" } ] } ] }, { "uniprot_canonical_ac": "P41821-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Cys531", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Functionally impaired.", "evidence": [ { "database": "UniProtKB", "id": "P41821", "url": "https://www.uniprot.org/uniprotkb/P41821" }, { "database": "PubMed", "id": "11796727", "url": "https://glygen.org/publication/PubMed/11796727" } ] } ] } ], "record_id": "P41821-1" }, { "uniprot_canonical_ac": "P41833-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 600, "chemical_mass": 69396.0, "gene_names": "IME4;G1337;IME4;SPO8", "protein_name": "N(6)-adenosine-methyltransferase IME4", "disease": [ { "disease_id": "DOID:5223", "name": "infertility", "description": "", "url": "https://disease-ontology.org/term/DOID:5223", "evidence": [ { "id": "5223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5223" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA m(6)A methyltransferase activity", "id": "GO:0001734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001734", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" } ], "cellular_component": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA modification", "id": "GO:0016556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016556", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" }, { "name": "meiotic DNA replication initiation", "id": "GO:1902974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902974", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" }, { "name": "negative regulation of pseudohyphal growth", "id": "GO:2000221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000221", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41833-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003160", "url": "https://www.yeastgenome.org/locus/S000003160" }, { "database": "iPTMnet", "id": "P41833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41833" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41833-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Asp348", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Impairs ability to sporulate.", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" }, { "database": "PubMed", "id": "12384598", "url": "https://glygen.org/publication/PubMed/12384598" } ] } ] }, { "uniprot_canonical_ac": "P41833-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Trp351", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Impairs ability to sporulate.", "evidence": [ { "database": "UniProtKB", "id": "P41833", "url": "https://www.uniprot.org/uniprotkb/P41833" }, { "database": "PubMed", "id": "12384598", "url": "https://glygen.org/publication/PubMed/12384598" } ] } ] } ], "record_id": "P41833-1" }, { "uniprot_canonical_ac": "P41835-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41835", "url": "https://www.uniprot.org/uniprotkb/P41835" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 540, "chemical_mass": 58059.0, "gene_names": "THI6;THI6", "protein_name": "Thiamine biosynthetic bifunctional enzyme", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P41835", "url": "https://www.uniprot.org/uniprotkb/P41835" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P41835", "url": "https://www.uniprot.org/uniprotkb/P41835" } ], "pmid": "" }, { "name": "hydroxyethylthiazole kinase activity", "id": "GO:0004417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004417", "evidence": [ { "database": "UniProtKB", "id": "P41835", "url": "https://www.uniprot.org/uniprotkb/P41835" } ], "pmid": "" }, { "name": "thiamine-phosphate diphosphorylase activity", "id": "GO:0004789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004789", "evidence": [ { "database": "UniProtKB", "id": "P41835", "url": "https://www.uniprot.org/uniprotkb/P41835" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P41835", "url": "https://www.uniprot.org/uniprotkb/P41835" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P41835", "url": "https://www.uniprot.org/uniprotkb/P41835" } ], "pmid": "" } ], "biological_process": [ { "name": "thiamine diphosphate biosynthetic process", "id": "GO:0009229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009229", "evidence": [ { "database": "UniProtKB", "id": "P41835", "url": "https://www.uniprot.org/uniprotkb/P41835" } ], "pmid": "" }, { "name": "thiamine biosynthetic process", "id": "GO:0009228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009228", "evidence": [ { "database": "UniProtKB", "id": "P41835", "url": "https://www.uniprot.org/uniprotkb/P41835" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P41835-1" }, { "uniprot_canonical_ac": "P41895-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 735, "chemical_mass": 82194.0, "gene_names": "TFG1;G7526;RAP74;SSU71;TFG1", "protein_name": "Transcription initiation factor IIF subunit alpha", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" }, { "name": "protein phosphatase activator activity", "id": "GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" }, { "name": "TFIIF-class transcription factor complex binding", "id": "GO:0001096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001096", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" }, { "name": "transcription factor TFIIF complex", "id": "GO:0005674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005674", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" }, { "name": "transcriptional start site selection at RNA polymerase II promoter", "id": "GO:0001174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001174", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41895-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Thr16", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Thr176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33933450", "url": "https://glygen.org/publication/PubMed/33933450" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Thr200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33933450", "url": "https://glygen.org/publication/PubMed/33933450" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Thr202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Thr271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Thr305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "33933450", "url": "https://glygen.org/publication/PubMed/33933450" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Ser463", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Ser515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Ser54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "560", "end_pos": "560", "site_lbl": "Ser560", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "562", "end_pos": "562", "site_lbl": "Ser562", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "571", "end_pos": "571", "site_lbl": "Ser571", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33933450", "url": "https://glygen.org/publication/PubMed/33933450" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "579", "end_pos": "579", "site_lbl": "Ser579", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "581", "end_pos": "581", "site_lbl": "Thr581", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Ser585", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Thr652", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "655", "end_pos": "655", "site_lbl": "Ser655", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41895", "url": "https://www.uniprot.org/uniprotkb/P41895" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33933450", "url": "https://glygen.org/publication/PubMed/33933450" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "666", "end_pos": "666", "site_lbl": "Thr666", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41895-1", "start_pos": "673", "end_pos": "673", "site_lbl": "Thr673", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41895" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003418", "url": "https://www.yeastgenome.org/locus/S000003418" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41895-1" }, { "uniprot_canonical_ac": "P41901-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 512, "chemical_mass": 59845.0, "gene_names": "SPR3;SPR3", "protein_name": "Sporulation-regulated protein 3", "disease": [], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" } ], "cellular_component": [ { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "ascospore wall", "id": "GO:0005619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005619", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" }, { "name": "ascospore formation", "id": "GO:0030437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030437", "evidence": [ { "database": "UniProtKB", "id": "P41901", "url": "https://www.uniprot.org/uniprotkb/P41901" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P41901-1" }, { "uniprot_canonical_ac": "P41903-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 349, "chemical_mass": 40260.0, "gene_names": "TES1;J1456;PTE1;TES1", "protein_name": "Peroxisomal acyl-coenzyme A thioester hydrolase 1", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" }, { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" }, { "name": "fatty acid catabolic process", "id": "GO:0009062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009062", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" }, { "name": "fatty acid oxidation", "id": "GO:0019395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019395", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" }, { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" }, { "name": "palmitoyl-(protein) hydrolase activity", "id": "GO:0008474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008474", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" }, { "name": "long-chain fatty acyl-CoA hydrolase activity", "id": "GO:0052816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052816", "evidence": [ { "database": "UniProtKB", "id": "P41903", "url": "https://www.uniprot.org/uniprotkb/P41903" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P41903-1" }, { "uniprot_canonical_ac": "P41911-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 440, "chemical_mass": 49422.0, "gene_names": "GPD2;GPD2;GPD3;O1222", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)] 2, mitochondrial", "disease": [ { "disease_id": "DOID:0110219", "name": "Brugada syndrome 2", "description": "A Brugada syndrome that has_material_basis_in heterozygous mutation in the GPD1L gene on chromosome 3p22.", "url": "https://disease-ontology.org/term/DOID:0110219", "evidence": [ { "id": "0110219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110219" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "pmid": "" }, { "name": "glycerol-3-phosphate dehydrogenase [NAD(P)+] activity", "id": "GO:0047952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047952", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "pmid": "" }, { "name": "glycerol-3-phosphate dehydrogenase (NAD+) activity", "id": "GO:0141152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141152", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "pmid": "" } ], "biological_process": [ { "name": "glycerol metabolic process", "id": "GO:0006071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006071", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "pmid": "" }, { "name": "glycerol-3-phosphate metabolic process", "id": "GO:0006072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006072", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "pmid": "" }, { "name": "glycerol-3-phosphate catabolic process", "id": "GO:0046168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046168", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41911-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Ser207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005420", "url": "https://www.yeastgenome.org/locus/S000005420" }, { "database": "iPTMnet", "id": "P41911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41911" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41911-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P41911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41911" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005420", "url": "https://www.yeastgenome.org/locus/S000005420" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41911-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P41911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41911" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005420", "url": "https://www.yeastgenome.org/locus/S000005420" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41911-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41911", "url": "https://www.uniprot.org/uniprotkb/P41911" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P41911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41911" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005420", "url": "https://www.yeastgenome.org/locus/S000005420" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41911-1" }, { "uniprot_canonical_ac": "P41920-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 201, "chemical_mass": 22953.0, "gene_names": "YRB1;CST20;HTN1;SFO1;STP52;YD8119.08;YRB1", "protein_name": "Ran-specific GTPase-activating protein 1", "disease": [ { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "pmid": "" } ], "biological_process": [ { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "pmid": "" }, { "name": "nuclear export", "id": "GO:0051168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051168", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41920-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002409", "url": "https://www.yeastgenome.org/locus/S000002409" }, { "database": "iPTMnet", "id": "P41920", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41920" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41920-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002409", "url": "https://www.yeastgenome.org/locus/S000002409" }, { "database": "iPTMnet", "id": "P41920", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41920" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41920-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41920", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41920" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002409", "url": "https://www.yeastgenome.org/locus/S000002409" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41920-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002409", "url": "https://www.yeastgenome.org/locus/S000002409" }, { "database": "iPTMnet", "id": "P41920", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41920" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41920-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Thr50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41920", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41920" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002409", "url": "https://www.yeastgenome.org/locus/S000002409" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41920-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41920", "url": "https://www.uniprot.org/uniprotkb/P41920" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P41920", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41920" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002409", "url": "https://www.yeastgenome.org/locus/S000002409" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41920-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Thr78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002409", "url": "https://www.yeastgenome.org/locus/S000002409" }, { "database": "iPTMnet", "id": "P41920", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41920" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41920-1" }, { "uniprot_canonical_ac": "P41921-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 483, "chemical_mass": 53441.0, "gene_names": "GLR1;GLR1;LPG17W;LPG17", "protein_name": "Glutathione reductase", "disease": [ { "disease_id": "DOID:0050859", "name": "hemorrhagic cystitis", "description": "A cystitis that is characterized by dysuria, hematuria and hemorrhage located_in the lower urinary tract.", "url": "https://disease-ontology.org/term/DOID:0050859", "evidence": [ { "id": "0050859", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050859" } ], "weight": 0.0 }, { "disease_id": "DOID:0051009", "name": "congenital nonspherocytic hemolytic anemia 10", "description": "A congenital nonspherocytic hemolytic anemia that has_material_basis_in homozygous or compound heterozygous mutation in the GSR gene on chromosome 8p21.", "url": "https://disease-ontology.org/term/DOID:0051009", "evidence": [ { "id": "0051009", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051009" } ], "weight": 0.0 }, { "disease_id": "DOID:0080108", "name": "myoglobinuria", "description": "A myopathy that is characterized by an increased urinary excretion of myoglobin.", "url": "https://disease-ontology.org/term/DOID:0080108", "evidence": [ { "id": "0080108", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080108" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:0111363", "name": "Heinz body anemia", "description": "A congenital nonspherocytic hemolytic anemia characterized by nonspherocytic hemolytic anemia of Dacie type I with Heinz bodies seen in erythrocytes after splenectomy that has_material_basis_in heterozygous mutation in the HBA1, HBA2 or HBB genes on chromosome 11p15.4, 16p13.3, and 16p13.3, respectively.", "url": "https://disease-ontology.org/term/DOID:0111363", "evidence": [ { "id": "0111363", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111363" } ], "weight": 0.0 }, { "disease_id": "DOID:1037", "name": "lymphoid leukemia", "description": "A leukemia that has_material_basis_in a B-cell or T-cell lineage involving primarily the bone marrow and the peripheral blood.", "url": "https://disease-ontology.org/term/DOID:1037", "evidence": [ { "id": "1037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1037" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11476", "name": "osteoporosis", "description": "A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.", "url": "https://disease-ontology.org/term/DOID:11476", "evidence": [ { "id": "11476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11476" } ], "weight": 0.0 }, { "disease_id": "DOID:11713", "name": "diabetic angiopathy", "description": "A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes.", "url": "https://disease-ontology.org/term/DOID:11713", "evidence": [ { "id": "11713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11713" } ], "weight": 0.0 }, { "disease_id": "DOID:11724", "name": "limb-girdle muscular dystrophy", "description": "A muscular dystrophy that is characterized by weakening of the muscles of the hip and shoulders which comprise the limb girdle muscles.", "url": "https://disease-ontology.org/term/DOID:11724", "evidence": [ { "id": "11724", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11724" } ], "weight": 0.0 }, { "disease_id": "DOID:11758", "name": "iron deficiency anemia", "description": "A microcytic anemia that is characterized by pallor, fatigue, lightheadedness, and weakness and has_material_basis_in low total body iron causing impaired synthesis of red blood cells.", "url": "https://disease-ontology.org/term/DOID:11758", "evidence": [ { "id": "11758", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11758" } ], "weight": 0.0 }, { "disease_id": "DOID:12241", "name": "beta thalassemia", "description": "A thalassemia characterized by the reduced or absent synthesis of the beta globin chains of hemoglobin.", "url": "https://disease-ontology.org/term/DOID:12241", "evidence": [ { "id": "12241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12241" } ], "weight": 0.0 }, { "disease_id": "DOID:12556", "name": "acute kidney tubular necrosis", "description": "An acute kidney failure that is characterized by necrosis of epithelial tubule cells.", "url": "https://disease-ontology.org/term/DOID:12556", "evidence": [ { "id": "12556", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12556" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1307", "name": "dementia", "description": "A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior.", "url": "https://disease-ontology.org/term/DOID:1307", "evidence": [ { "id": "1307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1307" } ], "weight": 0.0 }, { "disease_id": "DOID:13328", "name": "diabetic cataract", "description": "A cataract that is characterized by loss of lens transparency secondary to hyperglycemia related to diabetes mellitus.", "url": "https://disease-ontology.org/term/DOID:13328", "evidence": [ { "id": "13328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13328" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:585", "name": "nephrolithiasis", "description": "A kidney disease characterized by the formation of stoney concentrations in the kidneys.", "url": "https://disease-ontology.org/term/DOID:585", "evidence": [ { "id": "585", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:585" } ], "weight": 0.0 }, { "disease_id": "DOID:589", "name": "congenital hemolytic anemia", "description": "", "url": "https://disease-ontology.org/term/DOID:589", "evidence": [ { "id": "589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:589" } ], "weight": 0.0 }, { "disease_id": "DOID:750", "name": "peptic ulcer disease", "description": "", "url": "https://disease-ontology.org/term/DOID:750", "evidence": [ { "id": "750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:750" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:7998", "name": "hyperthyroidism", "description": "A thyroid gland disease that involves an over production of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:7998", "evidence": [ { "id": "7998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7998" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:8680", "name": "alcoholic gastritis", "description": "", "url": "https://disease-ontology.org/term/DOID:8680", "evidence": [ { "id": "8680", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8680" } ], "weight": 0.0 }, { "disease_id": "DOID:8997", "name": "polycythemia vera", "description": "A myeloproliferative neoplasm characterized by erythroid hyperplasia, myeloid leukocytosis, thrombocytosis, and splenomegaly.", "url": "https://disease-ontology.org/term/DOID:8997", "evidence": [ { "id": "8997", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8997" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9669", "name": "senile cataract", "description": "A cataract that is characterized by thickening and loss of transparency of the lens with age progression, caused by a multifactorial etiology related to aging.", "url": "https://disease-ontology.org/term/DOID:9669", "evidence": [ { "id": "9669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9669" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" } ], "molecular_function": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" }, { "name": "glutathione-disulfide reductase (NADPH) activity", "id": "GO:0004362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004362", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" }, { "name": "protein glutathionylation", "id": "GO:0010731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010731", "evidence": [ { "database": "UniProtKB", "id": "P41921", "url": "https://www.uniprot.org/uniprotkb/P41921" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41921-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Asn278", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true, "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 278, "start_aa": "Asn", "end_pos": 278, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn278", "evidence": [ { "id": "P41921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41921#ptm_processing" }, { "id": "2HQM", "database": "PDB", "url": "https://www.rcsb.org/sequence/2HQM" }, { "id": "17554778", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/17554778" }, { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "mining_tool": "GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "GlycoSiteMiner_1.0" } ] } ] }, { "uniprot_canonical_ac": "P41921-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006012", "url": "https://www.yeastgenome.org/locus/S000006012" }, { "database": "iPTMnet", "id": "P41921", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41921" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41921-1", "start_pos": "342", "end_pos": "342", "site_lbl": "Thr342", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006012", "url": "https://www.yeastgenome.org/locus/S000006012" }, { "database": "iPTMnet", "id": "P41921", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41921" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41921-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Tyr396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41921", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41921" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P41921-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006012", "url": "https://www.yeastgenome.org/locus/S000006012" }, { "database": "iPTMnet", "id": "P41921", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41921" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41921-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006012", "url": "https://www.yeastgenome.org/locus/S000006012" }, { "database": "iPTMnet", "id": "P41921", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41921" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41921-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Ser475", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41921", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41921" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006012", "url": "https://www.yeastgenome.org/locus/S000006012" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41921-1" }, { "uniprot_canonical_ac": "P41939-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 412, "chemical_mass": 46562.0, "gene_names": "IDP2;IDP2;L9470.12", "protein_name": "Isocitrate dehydrogenase [NADP] cytoplasmic", "disease": [ { "disease_id": "DOID:0050575", "name": "D-2-hydroxyglutaric aciduria", "description": "An 2-hydroxyglutaric aciduria that involves developmental delay, seizures, weak muscle tone (hypotonia), and abnormalities in the largest part of the brain (the cerebrum), which controls many important functions such as muscle movement, speech, vision, thinking, emotion, and memory.", "url": "https://disease-ontology.org/term/DOID:0050575", "evidence": [ { "id": "0050575", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050575" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0080005", "name": "bone remodeling disease", "description": "A bone disease that results_in formation or resorption abnormalities located_in bone.", "url": "https://disease-ontology.org/term/DOID:0080005", "evidence": [ { "id": "0080005", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080005" } ], "weight": 0.0 }, { "disease_id": "DOID:0111352", "name": "D-2-hydroxyglutaric aciduria 2", "description": "A D-2-hydroxyglutaric aciduria that has_material_basis_in heterozygous mutation in IDH2 on 15q26.1.", "url": "https://disease-ontology.org/term/DOID:0111352", "evidence": [ { "id": "0111352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111352" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:417", "name": "autoimmune disease", "description": "An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.", "url": "https://disease-ontology.org/term/DOID:417", "evidence": [ { "id": "417", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:417" } ], "weight": 0.0 }, { "disease_id": "DOID:4928", "name": "intrahepatic cholangiocarcinoma", "description": "A cholangiocarcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree.", "url": "https://disease-ontology.org/term/DOID:4928", "evidence": [ { "id": "4928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4928" } ], "weight": 0.0 }, { "disease_id": "DOID:5016", "name": "hepatocellular clear cell carcinoma", "description": "", "url": "https://disease-ontology.org/term/DOID:5016", "evidence": [ { "id": "5016", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5016" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "biological_process": [ { "name": "NADP+ metabolic process", "id": "GO:0006739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006739", "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "pmid": "" }, { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "pmid": "" }, { "name": "isocitrate metabolic process", "id": "GO:0006102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006102", "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "pmid": "" }, { "name": "glyoxylate cycle", "id": "GO:0006097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006097", "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "pmid": "" }, { "name": "isocitrate dehydrogenase (NADP+) activity", "id": "GO:0004450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004450", "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P41939", "url": "https://www.uniprot.org/uniprotkb/P41939" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41939-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004164", "url": "https://www.yeastgenome.org/locus/S000004164" }, { "database": "iPTMnet", "id": "P41939", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41939" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41939-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Thr77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004164", "url": "https://www.yeastgenome.org/locus/S000004164" }, { "database": "iPTMnet", "id": "P41939", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41939" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P41939-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004164", "url": "https://www.yeastgenome.org/locus/S000004164" }, { "database": "iPTMnet", "id": "P41939", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41939" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P41939-1" }, { "uniprot_canonical_ac": "P41948-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 499, "chemical_mass": 53401.0, "gene_names": "MEP2;AMT2;MEP2;N1207;N1820", "protein_name": "Ammonium transporter MEP2", "disease": [ { "disease_id": "DOID:0050641", "name": "Rh deficiency syndrome", "description": "A hemolytic anemia that is characterized by deficiency of Rh antigens, has_material_basis_in homozygous or compound heterozygous mutation in the RHAG gene on chromosome 6p12.", "url": "https://disease-ontology.org/term/DOID:0050641", "evidence": [ { "id": "0050641", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050641" } ], "weight": 0.0 }, { "disease_id": "DOID:0050758", "name": "metabolic acidosis", "description": "An acquired metabolic disease that characterized by excessive production of acid.", "url": "https://disease-ontology.org/term/DOID:0050758", "evidence": [ { "id": "0050758", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050758" } ], "weight": 0.0 }, { "disease_id": "DOID:0111562", "name": "overhydrated hereditary stomatocytosis", "description": "A macrocytic anemia characterized by macrocytic hemolytic anemia and monovalent cation leak from red blood cells that has_material_basis_in heterozygous mutation in the RHAG gene on chromosome 6p12.3.", "url": "https://disease-ontology.org/term/DOID:0111562", "evidence": [ { "id": "0111562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111562" } ], "weight": 0.0 }, { "disease_id": "DOID:1074", "name": "kidney failure", "description": "A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood.", "url": "https://disease-ontology.org/term/DOID:1074", "evidence": [ { "id": "1074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1074" } ], "weight": 0.0 }, { "disease_id": "DOID:14219", "name": "renal tubular acidosis", "description": "A renal tubular transport disease characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic acidosis.", "url": "https://disease-ontology.org/term/DOID:14219", "evidence": [ { "id": "14219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14219" } ], "weight": 0.0 }, { "disease_id": "DOID:4175", "name": "Rh isoimmunization", "description": "", "url": "https://disease-ontology.org/term/DOID:4175", "evidence": [ { "id": "4175", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4175" } ], "weight": 0.0 }, { "disease_id": "DOID:4500", "name": "hypokalemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4500", "evidence": [ { "id": "4500", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4500" } ], "weight": 0.0 }, { "disease_id": "DOID:583", "name": "hemolytic anemia", "description": "A normocytic anemia that is characterized by the rate of descruction of red blood cells exceeding the rate than they can be made.", "url": "https://disease-ontology.org/term/DOID:583", "evidence": [ { "id": "583", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:583" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" } ], "pmid": "" } ], "molecular_function": [ { "name": "ammonium channel activity", "id": "GO:0008519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008519", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" } ], "pmid": "" } ], "biological_process": [ { "name": "ammonium transmembrane transport", "id": "GO:0072488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072488", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" } ], "pmid": "" }, { "name": "positive regulation of filamentous growth of a population of unicellular organisms", "id": "GO:1900430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900430", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" } ], "pmid": "" }, { "name": "pseudohyphal growth", "id": "GO:0007124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007124", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" } ], "pmid": "" }, { "name": "nitrogen utilization", "id": "GO:0019740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019740", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P41948-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Asn4", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 4, "start_aa": "Asn", "end_pos": 4, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn4", "evidence": [ { "id": "P41948", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41948#ptm_processing" }, { "id": "11069679", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11069679" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Impairs glycosylation.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "11069679", "url": "https://glygen.org/publication/PubMed/11069679" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "457", "end_pos": "457", "site_lbl": "Ser457", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "24476960", "url": "https://glygen.org/publication/PubMed/24476960" }, { "database": "PubMed", "id": "27088325", "url": "https://glygen.org/publication/PubMed/27088325" }, { "database": "iPTMnet", "id": "P41948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41948" }, { "database": "SGD", "id": "S000005086", "url": "https://www.yeastgenome.org/locus/S000005086" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "D", "comment": "Silences the autoinhibition of MEP2, conferring transport activity even in the absence of the NPR1 kinase.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "32069286", "url": "https://glygen.org/publication/PubMed/32069286" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "459", "end_pos": "459", "site_lbl": "Thr459", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41948" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005086", "url": "https://www.yeastgenome.org/locus/S000005086" }, { "database": "PubMed", "id": "24476960", "url": "https://glygen.org/publication/PubMed/24476960" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Ser460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005086", "url": "https://www.yeastgenome.org/locus/S000005086" }, { "database": "iPTMnet", "id": "P41948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41948" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ser484", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41948" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005086", "url": "https://www.yeastgenome.org/locus/S000005086" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Ser487", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41948" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005086", "url": "https://www.yeastgenome.org/locus/S000005086" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41948" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005086", "url": "https://www.yeastgenome.org/locus/S000005086" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "491", "end_pos": "491", "site_lbl": "Ser491", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P41948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41948" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005086", "url": "https://www.yeastgenome.org/locus/S000005086" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Thr492", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005086", "url": "https://www.yeastgenome.org/locus/S000005086" }, { "database": "iPTMnet", "id": "P41948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41948" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Thr495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005086", "url": "https://www.yeastgenome.org/locus/S000005086" }, { "database": "iPTMnet", "id": "P41948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41948" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Asp186", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Impairs transport activity.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "16477434", "url": "https://glygen.org/publication/PubMed/16477434" }, { "database": "PubMed", "id": "18434596", "url": "https://glygen.org/publication/PubMed/18434596" } ] }, { "sequence_org": "D", "sequence_mut": "E", "comment": "Decreases the affinity for the substrate.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "16477434", "url": "https://glygen.org/publication/PubMed/16477434" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Impairs transport activity.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "16477434", "url": "https://glygen.org/publication/PubMed/16477434" }, { "database": "PubMed", "id": "18434596", "url": "https://glygen.org/publication/PubMed/18434596" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "194", "end_pos": "194", "site_lbl": "His194", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Preserves transport activity while impairing the filamentation capacity.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "18434596", "url": "https://glygen.org/publication/PubMed/18434596" } ] }, { "sequence_org": "H", "sequence_mut": "E", "comment": "Leads to increased competence to acidify the submembrane pH while losing the signaling capability.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "32069286", "url": "https://glygen.org/publication/PubMed/32069286" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "199", "end_pos": "199", "site_lbl": "His199", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "Circumvents the requirement of the CTD to enhance substrate trans-location through the hydrophobic core.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "32069286", "url": "https://glygen.org/publication/PubMed/32069286" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Asn252", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Does not affect glycosylation.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "11069679", "url": "https://glygen.org/publication/PubMed/11069679" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "348", "end_pos": "348", "site_lbl": "His348", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Preserves transport activity while impairing the filamentation capacity.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "18434596", "url": "https://glygen.org/publication/PubMed/18434596" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Gly349", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "C", "comment": "Circumvents the requirement of the CTD to enhance substrate trans-location through the hydrophobic core.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "32069286", "url": "https://glygen.org/publication/PubMed/32069286" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Asn368", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Does not affect glycosylation.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "11069679", "url": "https://glygen.org/publication/PubMed/11069679" } ] } ] }, { "uniprot_canonical_ac": "P41948-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Asn483", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Does not affect glycosylation.", "evidence": [ { "database": "UniProtKB", "id": "P41948", "url": "https://www.uniprot.org/uniprotkb/P41948" }, { "database": "PubMed", "id": "11069679", "url": "https://glygen.org/publication/PubMed/11069679" } ] } ] } ], "record_id": "P41948-1" }, { "uniprot_canonical_ac": "P42835-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P42835", "url": "https://www.uniprot.org/uniprotkb/P42835" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1041, "chemical_mass": 108525.0, "gene_names": "EGT2;EGT2;N0320", "protein_name": "Protein EGT2", "disease": [], "biological_process": [ { "name": "septum digestion after cytokinesis", "id": "GO:0000920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000920", "evidence": [ { "database": "UniProtKB", "id": "P42835", "url": "https://www.uniprot.org/uniprotkb/P42835" } ], "pmid": "" } ], "cellular_component": [ { "name": "cell septum", "id": "GO:0030428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030428", "evidence": [ { "database": "UniProtKB", "id": "P42835", "url": "https://www.uniprot.org/uniprotkb/P42835" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P42835", "url": "https://www.uniprot.org/uniprotkb/P42835" } ], "pmid": "" }, { "name": "cellular bud scar", "id": "GO:0005621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005621", "evidence": [ { "database": "UniProtKB", "id": "P42835", "url": "https://www.uniprot.org/uniprotkb/P42835" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "P42835", "url": "https://www.uniprot.org/uniprotkb/P42835" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P42835", "url": "https://www.uniprot.org/uniprotkb/P42835" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P42835", "url": "https://www.uniprot.org/uniprotkb/P42835" } ], "pmid": "" } ], "molecular_function": [ { "name": "cellulase activity", "id": "GO:0008810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008810", "evidence": [ { "database": "UniProtKB", "id": "P42835", "url": "https://www.uniprot.org/uniprotkb/P42835" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P42835-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Asn103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 103, "start_aa": "Asn", "end_pos": 103, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn103", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Asn161", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 161, "start_aa": "Asn", "end_pos": 161, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn161", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Asn175", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 175, "start_aa": "Asn", "end_pos": 175, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn175", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Asn249", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 249, "start_aa": "Asn", "end_pos": 249, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn249", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Asn332", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 332, "start_aa": "Asn", "end_pos": 332, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn332", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Asn401", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 401, "start_aa": "Asn", "end_pos": 401, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn401", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Asn435", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 435, "start_aa": "Asn", "end_pos": 435, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn435", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "465", "end_pos": "465", "site_lbl": "Asn465", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 465, "start_aa": "Asn", "end_pos": 465, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn465", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "485", "end_pos": "485", "site_lbl": "Asn485", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 485, "start_aa": "Asn", "end_pos": 485, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn485", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Asn506", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 506, "start_aa": "Asn", "end_pos": 506, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn506", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Asn526", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 526, "start_aa": "Asn", "end_pos": 526, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn526", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Asn544", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 544, "start_aa": "Asn", "end_pos": 544, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn544", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "556", "end_pos": "556", "site_lbl": "Asn556", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 556, "start_aa": "Asn", "end_pos": 556, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn556", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "635", "end_pos": "635", "site_lbl": "Asn635", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 635, "start_aa": "Asn", "end_pos": 635, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn635", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "636", "end_pos": "636", "site_lbl": "Asn636", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 636, "start_aa": "Asn", "end_pos": 636, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn636", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "657", "end_pos": "657", "site_lbl": "Asn657", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 657, "start_aa": "Asn", "end_pos": 657, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn657", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Asn65", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 65, "start_aa": "Asn", "end_pos": 65, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn65", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "709", "end_pos": "709", "site_lbl": "Asn709", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 709, "start_aa": "Asn", "end_pos": 709, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn709", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42835-1", "start_pos": "756", "end_pos": "756", "site_lbl": "Asn756", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 756, "start_aa": "Asn", "end_pos": 756, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn756", "evidence": [ { "id": "P42835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42835#ptm_processing" } ] } ] } ], "record_id": "P42835-1" }, { "uniprot_canonical_ac": "P42836-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 336, "chemical_mass": 39184.0, "gene_names": "PFA3;N0325;PFA3", "protein_name": "Palmitoyltransferase PFA3", "disease": [ { "disease_id": "DOID:225", "name": "syndrome", "description": "A disease characterized by a group of signs and symptoms that occur together and characterize a particular abnormality.", "url": "https://disease-ontology.org/term/DOID:225", "evidence": [ { "id": "225", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:225" } ], "weight": 0.0 } ], "biological_process": [ { "name": "vacuole fusion, non-autophagic", "id": "GO:0042144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042144", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "pmid": "" }, { "name": "protein palmitoylation", "id": "GO:0018345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018345", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "pmid": "" }, { "name": "palmitoyltransferase activity", "id": "GO:0016409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016409", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P42836-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Thr318", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 318, "start_aa": "Thr", "end_pos": 318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr318", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42836", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42836" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005270", "url": "https://www.yeastgenome.org/locus/S000005270" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42836-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Ser322", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42836", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42836" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005270", "url": "https://www.yeastgenome.org/locus/S000005270" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42836-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Ser329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42836", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42836" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005270", "url": "https://www.yeastgenome.org/locus/S000005270" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42836-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Cys134", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes autopalmitoylation and VAC8 palmitoylation.", "evidence": [ { "database": "UniProtKB", "id": "P42836", "url": "https://www.uniprot.org/uniprotkb/P42836" }, { "database": "PubMed", "id": "16186255", "url": "https://glygen.org/publication/PubMed/16186255" } ] } ] } ], "record_id": "P42836-1" }, { "uniprot_canonical_ac": "P42839-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 908, "chemical_mass": 102499.0, "gene_names": "VNX1;N0339;VNX1", "protein_name": "Low affinity vacuolar monovalent cation/H(+) antiporter", "disease": [], "molecular_function": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" }, { "name": "calcium:proton antiporter activity", "id": "GO:0015369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015369", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" }, { "name": "vacuole-mitochondrion membrane contact site", "id": "GO:1990816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990816", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" }, { "name": "potassium ion transport", "id": "GO:0006813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006813", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P42839-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Thr26", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 26, "start_aa": "Thr", "end_pos": 26, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr26", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 28, "start_aa": "Thr", "end_pos": 28, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr28", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Thr29", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 29, "start_aa": "Thr", "end_pos": 29, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr29", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 30, "start_aa": "Ser", "end_pos": 30, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser30", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 32, "start_aa": "Ser", "end_pos": 32, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser32", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 33, "start_aa": "Thr", "end_pos": 33, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr33", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 353, "start_aa": "Ser", "end_pos": 353, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser353", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 354, "start_aa": "Ser", "end_pos": 354, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser354", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Ser355", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 355, "start_aa": "Ser", "end_pos": 355, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser355", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Asn361", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 361, "start_aa": "Asn", "end_pos": 361, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn361", "evidence": [ { "id": "P42839", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42839#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 369, "start_aa": "Ser", "end_pos": 369, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser369", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "373", "end_pos": "373", "site_lbl": "Ser373", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 373, "start_aa": "Ser", "end_pos": 373, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser373", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Ser376", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 376, "start_aa": "Ser", "end_pos": 376, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser376", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42839", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42839" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Thr116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Thr118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42839", "url": "https://www.uniprot.org/uniprotkb/P42839" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Ser336", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42839-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005265", "url": "https://www.yeastgenome.org/locus/S000005265" }, { "database": "iPTMnet", "id": "P42839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42839" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P42839-1" }, { "uniprot_canonical_ac": "P42843-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P42843", "url": "https://www.uniprot.org/uniprotkb/P42843" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 763, "chemical_mass": 88942.0, "gene_names": "SKP2;N0376;SKP2", "protein_name": "F-box protein SKP2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P42843", "url": "https://www.uniprot.org/uniprotkb/P42843" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "P42843", "url": "https://www.uniprot.org/uniprotkb/P42843" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P42843", "url": "https://www.uniprot.org/uniprotkb/P42843" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P42843", "url": "https://www.uniprot.org/uniprotkb/P42843" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "P42843", "url": "https://www.uniprot.org/uniprotkb/P42843" } ], "pmid": "" }, { "name": "regulation of cysteine metabolic process", "id": "GO:1901494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901494", "evidence": [ { "database": "UniProtKB", "id": "P42843", "url": "https://www.uniprot.org/uniprotkb/P42843" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P42843-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Thr490", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 490, "start_aa": "Thr", "end_pos": 490, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr490", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P42843-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005255", "url": "https://www.yeastgenome.org/locus/S000005255" }, { "database": "iPTMnet", "id": "P42843", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42843" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42843-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Ser402", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005255", "url": "https://www.yeastgenome.org/locus/S000005255" }, { "database": "iPTMnet", "id": "P42843", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42843" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42843-1", "start_pos": "411", "end_pos": "411", "site_lbl": "Ser411", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42843", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42843" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P42843-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005255", "url": "https://www.yeastgenome.org/locus/S000005255" }, { "database": "iPTMnet", "id": "P42843", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42843" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42843-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Thr461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005255", "url": "https://www.yeastgenome.org/locus/S000005255" }, { "database": "iPTMnet", "id": "P42843", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42843" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42843-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Ser470", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005255", "url": "https://www.yeastgenome.org/locus/S000005255" }, { "database": "iPTMnet", "id": "P42843", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42843" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42843-1", "start_pos": "594", "end_pos": "594", "site_lbl": "Thr594", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42843", "url": "https://www.uniprot.org/uniprotkb/P42843" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P42843", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42843" }, { "database": "SGD", "id": "S000005255", "url": "https://www.yeastgenome.org/locus/S000005255" } ] } ] }, { "uniprot_canonical_ac": "P42843-1", "start_pos": "636", "end_pos": "636", "site_lbl": "Ser636", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005255", "url": "https://www.yeastgenome.org/locus/S000005255" }, { "database": "iPTMnet", "id": "P42843", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42843" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P42843-1" }, { "uniprot_canonical_ac": "P42844-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 174, "chemical_mass": 19855.0, "gene_names": "ZIM17;FMP28;HEP1;N0381;TIM15;ZIM17", "protein_name": "Mitochondrial protein import protein ZIM17", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "pmid": "" } ], "biological_process": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P42844-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Asp111", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes interaction with SSC1, and leads to self-aggregation of mtHSP70 and accumulation of uncleaved precursor proteins.", "evidence": [ { "database": "UniProtKB", "id": "P42844", "url": "https://www.uniprot.org/uniprotkb/P42844" }, { "database": "PubMed", "id": "17571076", "url": "https://glygen.org/publication/PubMed/17571076" } ] } ] } ], "record_id": "P42844-1" }, { "uniprot_canonical_ac": "P42845-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 420, "chemical_mass": 45684.0, "gene_names": "STB1;N0384;STB1", "protein_name": "Protein STB1", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "pmid": "" }, { "name": "MBF transcription complex", "id": "GO:0030907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030907", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "pmid": "" }, { "name": "SBF transcription complex", "id": "GO:0033309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033309", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "pmid": "" }, { "name": "positive regulation of mating type switching", "id": "GO:0031496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031496", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P42845-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 221, "start_aa": "Ser", "end_pos": 221, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser221", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42845", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42845" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 226, "start_aa": "Ser", "end_pos": 226, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser226", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42845", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42845" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 229, "start_aa": "Ser", "end_pos": 229, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser229", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42845", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42845" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Ser236", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 236, "start_aa": "Ser", "end_pos": 236, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser236", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42845", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42845" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Ser238", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 238, "start_aa": "Ser", "end_pos": 238, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser238", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42845", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42845" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 245, "start_aa": "Ser", "end_pos": 245, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser245", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42845", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42845" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Ser250", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 250, "start_aa": "Ser", "end_pos": 250, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser250", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42845", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42845" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Ser252", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 252, "start_aa": "Ser", "end_pos": 252, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser252", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42845", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42845" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Ser253", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 253, "start_aa": "Ser", "end_pos": 253, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser253", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42845", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42845" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 256, "start_aa": "Ser", "end_pos": 256, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser256", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P42845", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P42845" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Thr122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Thr125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Thr152", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ser164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Thr209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Thr218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Thr257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "413", "end_pos": "413", "site_lbl": "Ser413", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Thr419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Thr86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Ser89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42845-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Thr99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P42845", "url": "https://www.uniprot.org/uniprotkb/P42845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P42845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42845" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005253", "url": "https://www.yeastgenome.org/locus/S000005253" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P42845-1" }, { "uniprot_canonical_ac": "P42884-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P42884", "url": "https://www.uniprot.org/uniprotkb/P42884" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 376, "chemical_mass": 41991.0, "gene_names": "AAD14;AAD14;N0300", "protein_name": "Putative aryl-alcohol dehydrogenase AAD14", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 } ], "biological_process": [ { "name": "aldehyde metabolic process", "id": "GO:0006081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006081", "evidence": [ { "database": "UniProtKB", "id": "P42884", "url": "https://www.uniprot.org/uniprotkb/P42884" } ], "pmid": "" } ], "molecular_function": [ { "name": "aryl-alcohol dehydrogenase (NADP+) activity", "id": "GO:0047681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047681", "evidence": [ { "database": "UniProtKB", "id": "P42884", "url": "https://www.uniprot.org/uniprotkb/P42884" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P42884-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Ser363", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005275", "url": "https://www.yeastgenome.org/locus/S000005275" }, { "database": "iPTMnet", "id": "P42884", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42884" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P42884-1" }, { "uniprot_canonical_ac": "P42945-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1769, "chemical_mass": 200082.0, "gene_names": "UTP10;J0808;UTP10", "protein_name": "U3 small nucleolar RNA-associated protein 10", "disease": [ { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "rDNA heterochromatin", "id": "GO:0033553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033553", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "t-UTP complex", "id": "GO:0034455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034455", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" } ], "molecular_function": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" }, { "name": "U3 snoRNA binding", "id": "GO:0034511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034511", "evidence": [ { "database": "UniProtKB", "id": "P42945", "url": "https://www.uniprot.org/uniprotkb/P42945" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P42945-1", "start_pos": "1213", "end_pos": "1213", "site_lbl": "Ser1213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003645", "url": "https://www.yeastgenome.org/locus/S000003645" }, { "database": "iPTMnet", "id": "P42945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42945" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42945-1", "start_pos": "1384", "end_pos": "1384", "site_lbl": "Ser1384", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003645", "url": "https://www.yeastgenome.org/locus/S000003645" }, { "database": "iPTMnet", "id": "P42945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42945" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42945-1", "start_pos": "1388", "end_pos": "1388", "site_lbl": "Ser1388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003645", "url": "https://www.yeastgenome.org/locus/S000003645" }, { "database": "iPTMnet", "id": "P42945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42945" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42945-1", "start_pos": "1389", "end_pos": "1389", "site_lbl": "Ser1389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003645", "url": "https://www.yeastgenome.org/locus/S000003645" }, { "database": "iPTMnet", "id": "P42945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42945" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42945-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003645", "url": "https://www.yeastgenome.org/locus/S000003645" }, { "database": "iPTMnet", "id": "P42945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42945" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42945-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003645", "url": "https://www.yeastgenome.org/locus/S000003645" }, { "database": "iPTMnet", "id": "P42945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42945" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42945-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Thr72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P42945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42945" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P42945-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003645", "url": "https://www.yeastgenome.org/locus/S000003645" }, { "database": "iPTMnet", "id": "P42945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42945" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42945-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003645", "url": "https://www.yeastgenome.org/locus/S000003645" }, { "database": "iPTMnet", "id": "P42945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42945" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42945-1", "start_pos": "841", "end_pos": "841", "site_lbl": "Ser841", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003645", "url": "https://www.yeastgenome.org/locus/S000003645" }, { "database": "iPTMnet", "id": "P42945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42945" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P42945-1" }, { "uniprot_canonical_ac": "P42951-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 607, "chemical_mass": 70217.0, "gene_names": "LSB6;J0834;LSB6", "protein_name": "Phosphatidylinositol 4-kinase LSB6", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" }, { "name": "1-phosphatidylinositol 4-kinase activity", "id": "GO:0004430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004430", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" } ], "biological_process": [ { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "P42951", "url": "https://www.uniprot.org/uniprotkb/P42951" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P42951-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Thr169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003636", "url": "https://www.yeastgenome.org/locus/S000003636" }, { "database": "iPTMnet", "id": "P42951", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42951" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42951-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003636", "url": "https://www.yeastgenome.org/locus/S000003636" }, { "database": "iPTMnet", "id": "P42951", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42951" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42951-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003636", "url": "https://www.yeastgenome.org/locus/S000003636" }, { "database": "iPTMnet", "id": "P42951", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42951" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P42951-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003636", "url": "https://www.yeastgenome.org/locus/S000003636" }, { "database": "iPTMnet", "id": "P42951", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42951" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42951-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003636", "url": "https://www.yeastgenome.org/locus/S000003636" }, { "database": "iPTMnet", "id": "P42951", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42951" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P42951-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Ser320", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003636", "url": "https://www.yeastgenome.org/locus/S000003636" }, { "database": "iPTMnet", "id": "P42951", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42951" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P42951-1" }, { "uniprot_canonical_ac": "P43122-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 407, "chemical_mass": 45543.0, "gene_names": "QRI7;D2366;QRI7", "protein_name": "tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "disease": [], "molecular_function": [ { "name": "nucleotidase activity", "id": "GO:0008252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008252", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" } ], "pmid": "" }, { "name": "tRNA N(6)-L-threonylcarbamoyladenine synthase activity", "id": "GO:0061711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061711", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA threonylcarbamoyladenosine modification", "id": "GO:0002949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002949", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" } ], "pmid": "" }, { "name": "mitochondrial tRNA threonylcarbamoyladenosine modification", "id": "GO:0072670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072670", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43122-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Arg104", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces enzyme activity by 35%. Partially impairs dimer formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Lys130", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation. Partially impairs dimer formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Val134", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "R", "comment": "Severely impairs t(6)A37 formation. Prevents dimerization.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "145", "end_pos": "145", "site_lbl": "His145", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "149", "end_pos": "149", "site_lbl": "His149", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "K", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Arg207", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation. No effect on dimer formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Ser258", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation. No effect on dimer formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Asp361", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Glu39", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Asp43", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation. No effect on dimer formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Asp44", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation. No effect on dimer formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P43122-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ile77", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "E", "comment": "Severely impairs t(6)A37 formation. No effect on dimer formation.", "evidence": [ { "database": "UniProtKB", "id": "P43122", "url": "https://www.uniprot.org/uniprotkb/P43122" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] } ], "record_id": "P43122-1" }, { "uniprot_canonical_ac": "P43123-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 477, "chemical_mass": 53476.0, "gene_names": "QRI1;D2362;QRI1;UAP1", "protein_name": "UDP-N-acetylglucosamine pyrophosphorylase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" } ], "pmid": "" } ], "biological_process": [ { "name": "UDP-N-acetylglucosamine biosynthetic process", "id": "GO:0006048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006048", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" } ], "pmid": "" } ], "molecular_function": [ { "name": "UDP-N-acetylglucosamine diphosphorylase activity", "id": "GO:0003977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003977", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43123-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002261", "url": "https://www.yeastgenome.org/locus/S000002261" }, { "database": "iPTMnet", "id": "P43123", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43123" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002261", "url": "https://www.yeastgenome.org/locus/S000002261" }, { "database": "iPTMnet", "id": "P43123", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43123" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Ser406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002261", "url": "https://www.yeastgenome.org/locus/S000002261" }, { "database": "iPTMnet", "id": "P43123", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43123" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Ser461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P43123", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43123" }, { "database": "SGD", "id": "S000002261", "url": "https://www.yeastgenome.org/locus/S000002261" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Ser471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002261", "url": "https://www.yeastgenome.org/locus/S000002261" }, { "database": "iPTMnet", "id": "P43123", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43123" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Gly111", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Decrease of activity.", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" }, { "database": "PubMed", "id": "9603950", "url": "https://glygen.org/publication/PubMed/9603950" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Gly112", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" }, { "database": "PubMed", "id": "9603950", "url": "https://glygen.org/publication/PubMed/9603950" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Gly114", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Decrease of activity.", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" }, { "database": "PubMed", "id": "9603950", "url": "https://glygen.org/publication/PubMed/9603950" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Thr115", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Decrease of activity.", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" }, { "database": "PubMed", "id": "9603950", "url": "https://glygen.org/publication/PubMed/9603950" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Arg116", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" }, { "database": "PubMed", "id": "9603950", "url": "https://glygen.org/publication/PubMed/9603950" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Leu117", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Decrease of activity.", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" }, { "database": "PubMed", "id": "9603950", "url": "https://glygen.org/publication/PubMed/9603950" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Pro122", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "Decrease of activity.", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" }, { "database": "PubMed", "id": "9603950", "url": "https://glygen.org/publication/PubMed/9603950" } ] } ] }, { "uniprot_canonical_ac": "P43123-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Lys123", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P43123", "url": "https://www.uniprot.org/uniprotkb/P43123" }, { "database": "PubMed", "id": "9603950", "url": "https://glygen.org/publication/PubMed/9603950" } ] } ] } ], "record_id": "P43123-1" }, { "uniprot_canonical_ac": "P43132-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43132", "url": "https://www.uniprot.org/uniprotkb/P43132" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 505, "chemical_mass": 58347.0, "gene_names": "BRE2;BRE2;CPS60", "protein_name": "COMPASS component BRE2", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P43132", "url": "https://www.uniprot.org/uniprotkb/P43132" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P43132", "url": "https://www.uniprot.org/uniprotkb/P43132" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P43132", "url": "https://www.uniprot.org/uniprotkb/P43132" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "P43132", "url": "https://www.uniprot.org/uniprotkb/P43132" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P43132", "url": "https://www.uniprot.org/uniprotkb/P43132" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "P43132", "url": "https://www.uniprot.org/uniprotkb/P43132" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43132-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43132", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43132" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004005", "url": "https://www.yeastgenome.org/locus/S000004005" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43132-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004005", "url": "https://www.yeastgenome.org/locus/S000004005" }, { "database": "iPTMnet", "id": "P43132", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43132" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43132-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Tyr16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43132", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43132" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P43132-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Thr179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004005", "url": "https://www.yeastgenome.org/locus/S000004005" }, { "database": "iPTMnet", "id": "P43132", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43132" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43132-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Ser227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43132", "url": "https://www.uniprot.org/uniprotkb/P43132" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P43132", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43132" }, { "database": "SGD", "id": "S000004005", "url": "https://www.yeastgenome.org/locus/S000004005" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43132-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Ser401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004005", "url": "https://www.yeastgenome.org/locus/S000004005" }, { "database": "iPTMnet", "id": "P43132", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43132" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P43132-1" }, { "uniprot_canonical_ac": "P43321-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 101, "chemical_mass": 11224.0, "gene_names": "SMD3;L9634.6;SLT16;SMD3", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "disease": [ { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "U4 snRNP", "id": "GO:0005687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005687", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "SMN-Sm protein complex", "id": "GO:0034719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034719", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "commitment complex", "id": "GO:0000243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000243", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "spliceosomal tri-snRNP complex", "id": "GO:0097526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097526", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" } ], "biological_process": [ { "name": "7-methylguanosine cap hypermethylation", "id": "GO:0036261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036261", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P43321", "url": "https://www.uniprot.org/uniprotkb/P43321" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P43321-1" }, { "uniprot_canonical_ac": "P43497-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43497", "url": "https://www.uniprot.org/uniprotkb/P43497" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 92, "chemical_mass": 8911.0, "gene_names": "CWP2;CWP2;LPR1;YKL096BW;YKL097W-A;YKL444", "protein_name": "Cell wall protein CWP2", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P43497", "url": "https://www.uniprot.org/uniprotkb/P43497" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P43497", "url": "https://www.uniprot.org/uniprotkb/P43497" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P43497", "url": "https://www.uniprot.org/uniprotkb/P43497" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of cell wall", "id": "GO:0005199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005199", "evidence": [ { "database": "UniProtKB", "id": "P43497", "url": "https://www.uniprot.org/uniprotkb/P43497" } ], "pmid": "" } ], "biological_process": [ { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P43497", "url": "https://www.uniprot.org/uniprotkb/P43497" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P43497-1" }, { "uniprot_canonical_ac": "P43534-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 340, "chemical_mass": 38592.0, "gene_names": "THI5;MOL2;THI5", "protein_name": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI5", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" } ], "pmid": "" }, { "name": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP", "id": "GO:0106344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106344", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" } ], "pmid": "" } ], "biological_process": [ { "name": "thiamine diphosphate biosynthetic process", "id": "GO:0009229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009229", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" } ], "pmid": "" }, { "name": "thiamine biosynthetic process", "id": "GO:0009228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009228", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43534-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Asn11", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Unable to sustain growth in thiamine-free medium.", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" }, { "database": "PubMed", "id": "23048037", "url": "https://glygen.org/publication/PubMed/23048037" } ] } ] }, { "uniprot_canonical_ac": "P43534-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Trp12", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Unable to sustain growth in thiamine-free medium.", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" }, { "database": "PubMed", "id": "23048037", "url": "https://glygen.org/publication/PubMed/23048037" } ] } ] }, { "uniprot_canonical_ac": "P43534-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Cys195", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Attenuates the coordination of ion and is unable to sustain growth in thiamine-free medium.", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" }, { "database": "PubMed", "id": "23048037", "url": "https://glygen.org/publication/PubMed/23048037" } ] } ] }, { "uniprot_canonical_ac": "P43534-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Cys196", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Attenuates the coordination of ion and is unable to sustain growth in thiamine-free medium.", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" }, { "database": "PubMed", "id": "23048037", "url": "https://glygen.org/publication/PubMed/23048037" } ] } ] }, { "uniprot_canonical_ac": "P43534-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Cys197", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Attenuates the coordination of ion and is unable to sustain growth in thiamine-free medium.", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" }, { "database": "PubMed", "id": "23048037", "url": "https://glygen.org/publication/PubMed/23048037" } ] } ] }, { "uniprot_canonical_ac": "P43534-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Cys199", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Attenuates the coordination of ion and is unable to sustain growth in thiamine-free medium.", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" }, { "database": "PubMed", "id": "23048037", "url": "https://glygen.org/publication/PubMed/23048037" } ] } ] }, { "uniprot_canonical_ac": "P43534-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Lys62", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Unable to sustain growth in thiamine-free medium.", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" }, { "database": "PubMed", "id": "23048037", "url": "https://glygen.org/publication/PubMed/23048037" } ] } ] }, { "uniprot_canonical_ac": "P43534-1", "start_pos": "66", "end_pos": "66", "site_lbl": "His66", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Unable to sustain growth in thiamine-free medium.", "evidence": [ { "database": "UniProtKB", "id": "P43534", "url": "https://www.uniprot.org/uniprotkb/P43534" }, { "database": "PubMed", "id": "23048037", "url": "https://glygen.org/publication/PubMed/23048037" } ] } ] } ], "record_id": "P43534-1" }, { "uniprot_canonical_ac": "P43555-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43555", "url": "https://www.uniprot.org/uniprotkb/P43555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 445, "chemical_mass": 50330.0, "gene_names": "EMP47;EMP47", "protein_name": "Protein EMP47", "disease": [ { "disease_id": "DOID:0061042", "name": "autosomal dominant intellectual developmental disorder 69", "description": "An autosomal dominant intellectual developmental disorder characterized by developmental delay with variably impaired intellectual development that has_material_basis_in heterozygous mutation in the LMAN2L gene on chromosome 2q11.", "url": "https://disease-ontology.org/term/DOID:0061042", "evidence": [ { "id": "0061042", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061042" } ], "weight": 0.0 }, { "disease_id": "DOID:0081215", "name": "autosomal recessive intellectual developmental disorder 52", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the LMAN2L gene on chromosome 2q11.", "url": "https://disease-ontology.org/term/DOID:0081215", "evidence": [ { "id": "0081215", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081215" } ], "weight": 0.0 }, { "disease_id": "DOID:2211", "name": "factor XIII deficiency", "description": "A blood coagulation disease that is characterized by easy bleeding, has_symptom prolonged umbilical cord bleeding, epistaxis, bleeding of the gums, menorrhagia, recurrent miscarriages, abnormal scar formation and wound healing, and hemarthrosis, and has_material_basis_in autosomal recessive inheritance of mutation of the F13A1 or F13B gene, which encodes Factor XIII, formally known as fibrin stabilizing factor.", "url": "https://disease-ontology.org/term/DOID:2211", "evidence": [ { "id": "2211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2211" } ], "weight": 0.0 }, { "disease_id": "DOID:2216", "name": "factor V deficiency", "description": "", "url": "https://disease-ontology.org/term/DOID:2216", "evidence": [ { "id": "2216", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2216" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P43555", "url": "https://www.uniprot.org/uniprotkb/P43555" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "P43555", "url": "https://www.uniprot.org/uniprotkb/P43555" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P43555", "url": "https://www.uniprot.org/uniprotkb/P43555" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "P43555", "url": "https://www.uniprot.org/uniprotkb/P43555" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P43555", "url": "https://www.uniprot.org/uniprotkb/P43555" } ], "pmid": "" } ], "biological_process": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P43555", "url": "https://www.uniprot.org/uniprotkb/P43555" } ], "pmid": "" } ], "molecular_function": [ { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "P43555", "url": "https://www.uniprot.org/uniprotkb/P43555" } ], "pmid": "" }, { "name": "carbohydrate derivative binding", "id": "GO:0097367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097367", "evidence": [ { "database": "UniProtKB", "id": "P43555", "url": "https://www.uniprot.org/uniprotkb/P43555" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P43555-1" }, { "uniprot_canonical_ac": "P43558-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43558", "url": "https://www.uniprot.org/uniprotkb/P43558" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 301, "chemical_mass": 33510.0, "gene_names": "OTU1;OTU1", "protein_name": "Ubiquitin thioesterase OTU1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P43558", "url": "https://www.uniprot.org/uniprotkb/P43558" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P43558", "url": "https://www.uniprot.org/uniprotkb/P43558" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P43558", "url": "https://www.uniprot.org/uniprotkb/P43558" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "P43558", "url": "https://www.uniprot.org/uniprotkb/P43558" } ], "pmid": "" } ], "biological_process": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "P43558", "url": "https://www.uniprot.org/uniprotkb/P43558" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P43558", "url": "https://www.uniprot.org/uniprotkb/P43558" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "P43558", "url": "https://www.uniprot.org/uniprotkb/P43558" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "P43558", "url": "https://www.uniprot.org/uniprotkb/P43558" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43558-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43558" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001850", "url": "https://www.yeastgenome.org/locus/S000001850" } ] } ] }, { "uniprot_canonical_ac": "P43558-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Ser262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001850", "url": "https://www.yeastgenome.org/locus/S000001850" }, { "database": "iPTMnet", "id": "P43558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43558-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Ser291", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001850", "url": "https://www.yeastgenome.org/locus/S000001850" }, { "database": "iPTMnet", "id": "P43558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43558-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Cys120", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P43558", "url": "https://www.uniprot.org/uniprotkb/P43558" }, { "database": "PubMed", "id": "16427015", "url": "https://glygen.org/publication/PubMed/16427015" } ] } ] } ], "record_id": "P43558-1" }, { "uniprot_canonical_ac": "P43561-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 622, "chemical_mass": 70880.0, "gene_names": "FET5;FET5", "protein_name": "Iron transport multicopper oxidase FET5", "disease": [], "biological_process": [ { "name": "iron ion transmembrane transport", "id": "GO:0034755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034755", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" }, { "name": "cellular response to iron ion starvation", "id": "GO:0010106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010106", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" }, { "name": "reductive iron assimilation", "id": "GO:0033215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033215", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" }, { "name": "transmembrane transporter complex", "id": "GO:1902495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902495", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" }, { "name": "ferroxidase complex", "id": "GO:1905862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905862", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" } ], "molecular_function": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" }, { "name": "ferroxidase activity", "id": "GO:0004322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004322", "evidence": [ { "database": "UniProtKB", "id": "P43561", "url": "https://www.uniprot.org/uniprotkb/P43561" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43561-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Asn115", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 115, "start_aa": "Asn", "end_pos": 115, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn115", "evidence": [ { "id": "P43561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43561#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43561-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Asn196", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 196, "start_aa": "Asn", "end_pos": 196, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn196", "evidence": [ { "id": "P43561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43561#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43561-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Asn200", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 200, "start_aa": "Asn", "end_pos": 200, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn200", "evidence": [ { "id": "P43561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43561#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43561-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Asn246", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 246, "start_aa": "Asn", "end_pos": 246, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn246", "evidence": [ { "id": "P43561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43561#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43561-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Asn24", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 24, "start_aa": "Asn", "end_pos": 24, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn24", "evidence": [ { "id": "P43561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43561#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43561-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Asn295", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 295, "start_aa": "Asn", "end_pos": 295, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn295", "evidence": [ { "id": "P43561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43561#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43561-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Asn364", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 364, "start_aa": "Asn", "end_pos": 364, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn364", "evidence": [ { "id": "P43561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43561#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43561-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Asn455", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 455, "start_aa": "Asn", "end_pos": 455, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn455", "evidence": [ { "id": "P43561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43561#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43561-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Asn86", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 86, "start_aa": "Asn", "end_pos": 86, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn86", "evidence": [ { "id": "P43561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43561#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43561-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Thr472", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43561", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43561" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001853", "url": "https://www.yeastgenome.org/locus/S000001853" } ] } ] } ], "record_id": "P43561-1" }, { "uniprot_canonical_ac": "P43563-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 287, "chemical_mass": 33276.0, "gene_names": "MOB2;MOB2;YFL035C-A;YFL035C", "protein_name": "CBK1 kinase activator protein MOB2", "disease": [], "biological_process": [ { "name": "septum digestion after cytokinesis", "id": "GO:0000920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000920", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" }, { "name": "positive regulation of protein phosphorylation", "id": "GO:0001934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001934", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" }, { "name": "budding cell apical bud growth", "id": "GO:0007118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007118", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43563-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 65, "start_aa": "Ser", "end_pos": 65, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser65", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P43563", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P43563" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Thr66", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P43563", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P43563" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 69, "start_aa": "Ser", "end_pos": 69, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser69", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P43563", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P43563" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Thr73", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P43563", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P43563" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 74, "start_aa": "Ser", "end_pos": 74, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser74", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P43563", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P43563" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 79, "start_aa": "Ser", "end_pos": 79, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser79", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P43563", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P43563" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 85, "start_aa": "Ser", "end_pos": 85, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser85", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P43563", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P43563" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Thr31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Tyr33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43563-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Thr76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43563", "url": "https://www.uniprot.org/uniprotkb/P43563" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P43563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43563" }, { "database": "SGD", "id": "S000001859", "url": "https://www.yeastgenome.org/locus/S000001859" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P43563-1" }, { "uniprot_canonical_ac": "P43564-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1073, "chemical_mass": 119510.0, "gene_names": "MIL1;MIL1", "protein_name": "Probable lipase MIL1", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" } ], "pmid": "" }, { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" } ], "pmid": "" }, { "name": "AP-1 adaptor complex binding", "id": "GO:0035650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035650", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" } ], "pmid": "" } ], "biological_process": [ { "name": "clathrin-coated vesicle cargo loading", "id": "GO:0035652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035652", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43564-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Asn190", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 190, "start_aa": "Asn", "end_pos": 190, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn190", "evidence": [ { "id": "P43564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43564#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Asn229", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 229, "start_aa": "Asn", "end_pos": 229, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn229", "evidence": [ { "id": "P43564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43564#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Asn236", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 236, "start_aa": "Asn", "end_pos": 236, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn236", "evidence": [ { "id": "P43564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43564#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Asn280", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 280, "start_aa": "Asn", "end_pos": 280, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn280", "evidence": [ { "id": "P43564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43564#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "411", "end_pos": "411", "site_lbl": "Asn411", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 411, "start_aa": "Asn", "end_pos": 411, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn411", "evidence": [ { "id": "P43564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43564#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Asn495", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 495, "start_aa": "Asn", "end_pos": 495, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn495", "evidence": [ { "id": "P43564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43564#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "726", "end_pos": "726", "site_lbl": "Asn726", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 726, "start_aa": "Asn", "end_pos": 726, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn726", "evidence": [ { "id": "P43564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43564#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "850", "end_pos": "850", "site_lbl": "Asn850", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 850, "start_aa": "Asn", "end_pos": 850, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn850", "evidence": [ { "id": "P43564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43564#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "1037", "end_pos": "1037", "site_lbl": "Ser1037", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "1045", "end_pos": "1045", "site_lbl": "Ser1045", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Thr176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Thr211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Thr215", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Ser240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Tyr260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Tyr263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Ser406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "418", "end_pos": "418", "site_lbl": "Thr418", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Thr426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Thr429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Ser435", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "785", "end_pos": "785", "site_lbl": "Tyr785", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "789", "end_pos": "789", "site_lbl": "Thr789", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Thr84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43564", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43564" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001860", "url": "https://www.yeastgenome.org/locus/S000001860" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "759", "end_pos": "759", "site_lbl": "Ser759", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Increases sensitivity to sertraline.", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" }, { "database": "PubMed", "id": "26658609", "url": "https://glygen.org/publication/PubMed/26658609" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "817", "end_pos": "817", "site_lbl": "Asp817", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Increases sensitivity to sertraline.", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" }, { "database": "PubMed", "id": "26658609", "url": "https://glygen.org/publication/PubMed/26658609" } ] } ] }, { "uniprot_canonical_ac": "P43564-1", "start_pos": "858", "end_pos": "858", "site_lbl": "His858", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Increases sensitivity to sertraline.", "evidence": [ { "database": "UniProtKB", "id": "P43564", "url": "https://www.uniprot.org/uniprotkb/P43564" }, { "database": "PubMed", "id": "26658609", "url": "https://glygen.org/publication/PubMed/26658609" } ] } ] } ], "record_id": "P43564-1" }, { "uniprot_canonical_ac": "P43567-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43567", "url": "https://www.uniprot.org/uniprotkb/P43567" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 385, "chemical_mass": 41907.0, "gene_names": "AGX1;AGX1", "protein_name": "Alanine--glyoxylate aminotransferase 1", "disease": [ { "disease_id": "DOID:0111670", "name": "primary hyperoxaluria type 1", "description": "A primary hyperoxaluria characterized by failure to transaminate glyoxylate resulting in accumulation of calcium oxalate in various tissues that has_material_basis_in homozygous or compound heterozygous mutation in the AGXT gene on chromosome 2q37.3.", "url": "https://disease-ontology.org/term/DOID:0111670", "evidence": [ { "id": "0111670", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111670" } ], "weight": 0.0 }, { "disease_id": "DOID:2977", "name": "primary hyperoxaluria", "description": "A carbohydrate metabolic disorder characterized by impaired glyoxylate metabolism resulting in accumulation of oxalate throughout the body typically manifesting as kidney and bladder stones.", "url": "https://disease-ontology.org/term/DOID:2977", "evidence": [ { "id": "2977", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2977" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "L-serine-pyruvate transaminase activity", "id": "GO:0004760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004760", "evidence": [ { "database": "UniProtKB", "id": "P43567", "url": "https://www.uniprot.org/uniprotkb/P43567" } ], "pmid": "" }, { "name": "alanine-glyoxylate transaminase activity", "id": "GO:0008453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008453", "evidence": [ { "database": "UniProtKB", "id": "P43567", "url": "https://www.uniprot.org/uniprotkb/P43567" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P43567", "url": "https://www.uniprot.org/uniprotkb/P43567" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P43567", "url": "https://www.uniprot.org/uniprotkb/P43567" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P43567", "url": "https://www.uniprot.org/uniprotkb/P43567" } ], "pmid": "" } ], "biological_process": [ { "name": "glycine biosynthetic process, by transamination of glyoxylate", "id": "GO:0019265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019265", "evidence": [ { "database": "UniProtKB", "id": "P43567", "url": "https://www.uniprot.org/uniprotkb/P43567" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43567-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P43567-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001864", "url": "https://www.yeastgenome.org/locus/S000001864" }, { "database": "iPTMnet", "id": "P43567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43567" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P43567-1" }, { "uniprot_canonical_ac": "P43571-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1029, "chemical_mass": 117755.0, "gene_names": "BST1;BST1;PER17", "protein_name": "GPI inositol-deacylase", "disease": [ { "disease_id": "DOID:4621", "name": "holoprosencephaly", "description": "A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies.", "url": "https://disease-ontology.org/term/DOID:4621", "evidence": [ { "id": "4621", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4621" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" }, { "name": "vesicle organization", "id": "GO:0016050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016050", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" }, { "name": "protein retention in ER lumen", "id": "GO:0006621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006621", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" }, { "name": "GPI anchor metabolic process", "id": "GO:0006505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006505", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" }, { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" }, { "name": "protein-lipid complex remodeling", "id": "GO:0034368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034368", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol deacylase activity", "id": "GO:0050185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050185", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" }, { "name": "deacylase activity", "id": "GO:0160215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160215", "evidence": [ { "database": "UniProtKB", "id": "P43571", "url": "https://www.uniprot.org/uniprotkb/P43571" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43571-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Asn19", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 19, "start_aa": "Asn", "end_pos": 19, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn19", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Asn295", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 295, "start_aa": "Asn", "end_pos": 295, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn295", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Asn302", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 302, "start_aa": "Asn", "end_pos": 302, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn302", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "447", "end_pos": "447", "site_lbl": "Asn447", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 447, "start_aa": "Asn", "end_pos": 447, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn447", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "456", "end_pos": "456", "site_lbl": "Asn456", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 456, "start_aa": "Asn", "end_pos": 456, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn456", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "485", "end_pos": "485", "site_lbl": "Asn485", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 485, "start_aa": "Asn", "end_pos": 485, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn485", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "565", "end_pos": "565", "site_lbl": "Asn565", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 565, "start_aa": "Asn", "end_pos": 565, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn565", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "651", "end_pos": "651", "site_lbl": "Asn651", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 651, "start_aa": "Asn", "end_pos": 651, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn651", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "668", "end_pos": "668", "site_lbl": "Asn668", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 668, "start_aa": "Asn", "end_pos": 668, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn668", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "694", "end_pos": "694", "site_lbl": "Asn694", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 694, "start_aa": "Asn", "end_pos": 694, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn694", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "918", "end_pos": "918", "site_lbl": "Asn918", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 918, "start_aa": "Asn", "end_pos": 918, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn918", "evidence": [ { "id": "P43571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43571#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001869", "url": "https://www.yeastgenome.org/locus/S000001869" }, { "database": "iPTMnet", "id": "P43571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43571" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43571-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001869", "url": "https://www.yeastgenome.org/locus/S000001869" }, { "database": "iPTMnet", "id": "P43571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43571" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P43571-1" }, { "uniprot_canonical_ac": "P43572-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 832, "chemical_mass": 96738.0, "gene_names": "EPL1;EPL1", "protein_name": "Enhancer of polycomb-like protein 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "pmid": "" }, { "name": "piccolo histone acetyltransferase complex", "id": "GO:0032777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032777", "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "pmid": "" }, { "name": "positive regulation of macroautophagy", "id": "GO:0016239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P43572", "url": "https://www.uniprot.org/uniprotkb/P43572" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43572-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Thr3", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3, "start_aa": "Thr", "end_pos": 3, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001870", "url": "https://www.yeastgenome.org/locus/S000001870" }, { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001870", "url": "https://www.yeastgenome.org/locus/S000001870" }, { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001870", "url": "https://www.yeastgenome.org/locus/S000001870" }, { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Ser385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001870", "url": "https://www.yeastgenome.org/locus/S000001870" }, { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Ser42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "645", "end_pos": "645", "site_lbl": "Ser645", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001870", "url": "https://www.yeastgenome.org/locus/S000001870" }, { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "686", "end_pos": "686", "site_lbl": "Ser686", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001870", "url": "https://www.yeastgenome.org/locus/S000001870" }, { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Ser713", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001870", "url": "https://www.yeastgenome.org/locus/S000001870" }, { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "804", "end_pos": "804", "site_lbl": "Ser804", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001870", "url": "https://www.yeastgenome.org/locus/S000001870" }, { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "814", "end_pos": "814", "site_lbl": "Ser814", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001870", "url": "https://www.yeastgenome.org/locus/S000001870" }, { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43572-1", "start_pos": "827", "end_pos": "827", "site_lbl": "Thr827", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001870", "url": "https://www.yeastgenome.org/locus/S000001870" }, { "database": "iPTMnet", "id": "P43572", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43572" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P43572-1" }, { "uniprot_canonical_ac": "P43593-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 499, "chemical_mass": 57111.0, "gene_names": "UBP6;UBP6", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 6", "disease": [ { "disease_id": "DOID:649", "name": "prion disease", "description": "A brain disease that is characterized by brain damage resulting from the abnormal folding, clumping and accumulation of cellular proteins in the brain induced by prion proteins.", "url": "https://disease-ontology.org/term/DOID:649", "evidence": [ { "id": "649", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:649" } ], "weight": 0.0 } ], "biological_process": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" } ], "pmid": "" }, { "name": "mitochondria-associated ubiquitin-dependent protein catabolic process", "id": "GO:0072671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072671", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" } ], "pmid": "" }, { "name": "regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032434", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" } ], "pmid": "" }, { "name": "negative regulation of proteasomal protein catabolic process", "id": "GO:1901799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901799", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" } ], "pmid": "" }, { "name": "negative regulation of ERAD pathway", "id": "GO:1904293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904293", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" } ], "pmid": "" } ], "cellular_component": [ { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" } ], "pmid": "" }, { "name": "proteasome regulatory particle", "id": "GO:0005838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005838", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" } ], "pmid": "" } ], "molecular_function": [ { "name": "proteasome binding", "id": "GO:0070628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070628", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43593-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Ser143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001906", "url": "https://www.yeastgenome.org/locus/S000001906" }, { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43593-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Thr244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P43593-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001906", "url": "https://www.yeastgenome.org/locus/S000001906" }, { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43593-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Ser295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001906", "url": "https://www.yeastgenome.org/locus/S000001906" }, { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43593-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001906", "url": "https://www.yeastgenome.org/locus/S000001906" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43593-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001906", "url": "https://www.yeastgenome.org/locus/S000001906" }, { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43593-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Ser382", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001906", "url": "https://www.yeastgenome.org/locus/S000001906" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43593-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Ser383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001906", "url": "https://www.yeastgenome.org/locus/S000001906" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43593-1", "start_pos": "384", "end_pos": "384", "site_lbl": "Ser384", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001906", "url": "https://www.yeastgenome.org/locus/S000001906" }, { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43593-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Thr389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001906", "url": "https://www.yeastgenome.org/locus/S000001906" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43593-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Ser470", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43593", "url": "https://www.uniprot.org/uniprotkb/P43593" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P43593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43593" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001906", "url": "https://www.yeastgenome.org/locus/S000001906" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P43593-1" }, { "uniprot_canonical_ac": "P43601-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 500, "chemical_mass": 55102.0, "gene_names": "ATG18;ATG18;AUT10;CVT18;NMR1;SVP1", "protein_name": "Autophagy-related protein 18", "disease": [ { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "positive regulation of vacuole organization", "id": "GO:0044090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044090", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "glycophagy", "id": "GO:0061723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061723", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "protein targeting to vacuole involved in autophagy", "id": "GO:0071211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071211", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "vacuolar protein processing", "id": "GO:0006624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006624", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process", "id": "GO:1903100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903100", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "regulation of phosphatidylinositol biosynthetic process", "id": "GO:0010511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010511", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "PAS complex", "id": "GO:0070772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070772", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "phagophore", "id": "GO:0061908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061908", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "CROP complex", "id": "GO:0170071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170071", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43601-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001917", "url": "https://www.yeastgenome.org/locus/S000001917" }, { "database": "iPTMnet", "id": "P43601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43601" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001917", "url": "https://www.yeastgenome.org/locus/S000001917" }, { "database": "iPTMnet", "id": "P43601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43601" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P43601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43601" }, { "database": "SGD", "id": "S000001917", "url": "https://www.yeastgenome.org/locus/S000001917" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Tyr381", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001917", "url": "https://www.yeastgenome.org/locus/S000001917" }, { "database": "iPTMnet", "id": "P43601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43601" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Ser383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001917", "url": "https://www.yeastgenome.org/locus/S000001917" }, { "database": "iPTMnet", "id": "P43601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43601" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Thr393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43601" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001917", "url": "https://www.yeastgenome.org/locus/S000001917" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001917", "url": "https://www.yeastgenome.org/locus/S000001917" }, { "database": "iPTMnet", "id": "P43601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43601" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Tyr47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "IntAct", "id": "P43601", "url": "https://www.ebi.ac.uk/intact/interactors/id:P43601*" }, { "database": "iPTMnet", "id": "P43601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43601" }, { "database": "PubMed", "id": "22333915", "url": "https://glygen.org/publication/PubMed/22333915" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Ser264", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Impairs membrane-association.", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" }, { "database": "PubMed", "id": "22753491", "url": "https://glygen.org/publication/PubMed/22753491" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Thr268", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Impairs membrane-association.", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" }, { "database": "PubMed", "id": "22753491", "url": "https://glygen.org/publication/PubMed/22753491" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Arg271", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs membrane-association.", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" }, { "database": "PubMed", "id": "22753491", "url": "https://glygen.org/publication/PubMed/22753491" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Arg285", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs membrane-association.", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" }, { "database": "PubMed", "id": "22753491", "url": "https://glygen.org/publication/PubMed/22753491" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Arg286", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs membrane-association.", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" }, { "database": "PubMed", "id": "22753491", "url": "https://glygen.org/publication/PubMed/22753491" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "311", "end_pos": "311", "site_lbl": "Ser311", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Impairs membrane-association.", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" }, { "database": "PubMed", "id": "22753491", "url": "https://glygen.org/publication/PubMed/22753491" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Thr313", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Impairs membrane-association.", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" }, { "database": "PubMed", "id": "22753491", "url": "https://glygen.org/publication/PubMed/22753491" } ] } ] }, { "uniprot_canonical_ac": "P43601-1", "start_pos": "315", "end_pos": "315", "site_lbl": "His315", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Impairs membrane-association.", "evidence": [ { "database": "UniProtKB", "id": "P43601", "url": "https://www.uniprot.org/uniprotkb/P43601" }, { "database": "PubMed", "id": "22753491", "url": "https://glygen.org/publication/PubMed/22753491" } ] } ] } ], "record_id": "P43601-1" }, { "uniprot_canonical_ac": "P43602-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43602", "url": "https://www.uniprot.org/uniprotkb/P43602" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 733, "chemical_mass": 79709.0, "gene_names": "ROG3;ART7;ROG3", "protein_name": "Protein ROG3", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:14525", "name": "Reye syndrome", "description": "A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.", "url": "https://disease-ontology.org/term/DOID:14525", "evidence": [ { "id": "14525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14525" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P43602", "url": "https://www.uniprot.org/uniprotkb/P43602" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P43602", "url": "https://www.uniprot.org/uniprotkb/P43602" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P43602", "url": "https://www.uniprot.org/uniprotkb/P43602" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P43602", "url": "https://www.uniprot.org/uniprotkb/P43602" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "P43602", "url": "https://www.uniprot.org/uniprotkb/P43602" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of receptor internalization", "id": "GO:0002092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002092", "evidence": [ { "database": "UniProtKB", "id": "P43602", "url": "https://www.uniprot.org/uniprotkb/P43602" } ], "pmid": "" }, { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "P43602", "url": "https://www.uniprot.org/uniprotkb/P43602" } ], "pmid": "" }, { "name": "cellular response to pheromone", "id": "GO:0071444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071444", "evidence": [ { "database": "UniProtKB", "id": "P43602", "url": "https://www.uniprot.org/uniprotkb/P43602" } ], "pmid": "" }, { "name": "conjugation with cellular fusion", "id": "GO:0000747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000747", "evidence": [ { "database": "UniProtKB", "id": "P43602", "url": "https://www.uniprot.org/uniprotkb/P43602" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43602-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Ser431", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "433", "end_pos": "433", "site_lbl": "Ser433", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Ser435", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Ser450", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Tyr468", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Ser473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Ser475", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Thr483", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "535", "end_pos": "535", "site_lbl": "Ser535", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "537", "end_pos": "537", "site_lbl": "Ser537", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "573", "end_pos": "573", "site_lbl": "Ser573", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Ser610", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Ser684", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "687", "end_pos": "687", "site_lbl": "Ser687", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "690", "end_pos": "690", "site_lbl": "Thr690", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "695", "end_pos": "695", "site_lbl": "Thr695", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "696", "end_pos": "696", "site_lbl": "Ser696", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "710", "end_pos": "710", "site_lbl": "Ser710", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "718", "end_pos": "718", "site_lbl": "Ser718", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43602-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001918", "url": "https://www.yeastgenome.org/locus/S000001918" }, { "database": "iPTMnet", "id": "P43602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43602" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] } ], "record_id": "P43602-1" }, { "uniprot_canonical_ac": "P43616-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 481, "chemical_mass": 52871.0, "gene_names": "DUG1;DUG1", "protein_name": "Cys-Gly metallodipeptidase DUG1", "disease": [ { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 } ], "biological_process": [ { "name": "glutathione catabolic process", "id": "GO:0006751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006751", "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" } ], "pmid": "" } ], "molecular_function": [ { "name": "omega peptidase activity", "id": "GO:0008242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008242", "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" } ], "pmid": "" }, { "name": "metallodipeptidase activity", "id": "GO:0070573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070573", "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43616-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Thr165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Ser173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "234", "end_pos": "234", "site_lbl": "Ser234", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Ser318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Ser375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "451", "end_pos": "451", "site_lbl": "Ser451", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43616", "url": "https://www.uniprot.org/uniprotkb/P43616" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "467", "end_pos": "467", "site_lbl": "Thr467", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Ser54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Thr6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43616-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001940", "url": "https://www.yeastgenome.org/locus/S000001940" }, { "database": "iPTMnet", "id": "P43616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P43616-1" }, { "uniprot_canonical_ac": "P43633-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 760, "chemical_mass": 86087.0, "gene_names": "ALK1;ALK1;G3686", "protein_name": "Serine/threonine-protein kinase Haspin homolog ALK1", "disease": [], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "pmid": "" }, { "name": "mitotic morphogenesis checkpoint signaling", "id": "GO:0044879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044879", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "pmid": "" }, { "name": "histone H3T3 kinase activity", "id": "GO:0072354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072354", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43633-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Thr126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Ser170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Thr172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Ser190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Ser212", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Ser251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Ser253", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Ser254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Ser257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Ser258", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Ser260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Ser261", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Thr262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Ser264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Ser291", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Ser303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Thr305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Ser318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Ser351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Ser356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Ser368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Ser374", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Tyr407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Ser419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "427", "end_pos": "427", "site_lbl": "Ser427", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "437", "end_pos": "437", "site_lbl": "Tyr437", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Thr439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "440", "end_pos": "440", "site_lbl": "Ser440", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "443", "end_pos": "443", "site_lbl": "Ser443", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "446", "end_pos": "446", "site_lbl": "Ser446", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "449", "end_pos": "449", "site_lbl": "Ser449", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P43633", "url": "https://www.uniprot.org/uniprotkb/P43633" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P43633-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Thr83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002989", "url": "https://www.yeastgenome.org/locus/S000002989" }, { "database": "iPTMnet", "id": "P43633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P43633-1" }, { "uniprot_canonical_ac": "P43635-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43635", "url": "https://www.uniprot.org/uniprotkb/P43635" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 486, "chemical_mass": 53811.0, "gene_names": "CIT3;CIT3;YP9723.01", "protein_name": "Citrate synthase 3, mitochondrial", "disease": [ { "disease_id": "DOID:0050852", "name": "limb ischemia", "description": "An ischemia that is characterized by low blood supply to tissues in the limb due to interruption in the arterial blood supply.", "url": "https://disease-ontology.org/term/DOID:0050852", "evidence": [ { "id": "0050852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050852" } ], "weight": 0.0 }, { "disease_id": "DOID:0051064", "name": "left ventricular failure", "description": "A congestive heart failure that is characterized by dysfunction of the left ventricle, resulting insufficient delivery of blood to vital organs.", "url": "https://disease-ontology.org/term/DOID:0051064", "evidence": [ { "id": "0051064", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051064" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:7998", "name": "hyperthyroidism", "description": "A thyroid gland disease that involves an over production of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:7998", "evidence": [ { "id": "7998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7998" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P43635", "url": "https://www.uniprot.org/uniprotkb/P43635" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P43635", "url": "https://www.uniprot.org/uniprotkb/P43635" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "P43635", "url": "https://www.uniprot.org/uniprotkb/P43635" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "P43635", "url": "https://www.uniprot.org/uniprotkb/P43635" } ], "pmid": "" }, { "name": "propionate catabolic process, 2-methylcitrate cycle", "id": "GO:0019629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019629", "evidence": [ { "database": "UniProtKB", "id": "P43635", "url": "https://www.uniprot.org/uniprotkb/P43635" } ], "pmid": "" } ], "molecular_function": [ { "name": "citrate synthase activity", "id": "GO:0036440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036440", "evidence": [ { "database": "UniProtKB", "id": "P43635", "url": "https://www.uniprot.org/uniprotkb/P43635" } ], "pmid": "" }, { "name": "2-methylcitrate synthase activity", "id": "GO:0050440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050440", "evidence": [ { "database": "UniProtKB", "id": "P43635", "url": "https://www.uniprot.org/uniprotkb/P43635" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P43635-1" }, { "uniprot_canonical_ac": "P43682-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 97, "chemical_mass": 10961.0, "gene_names": "SFT1;SFT1;YKL006BC", "protein_name": "Protein transport protein SFT1", "disease": [ { "disease_id": "DOID:13223", "name": "uterine fibroid", "description": "An uterine benign neoplasm derived from the smooth muscle layer of the uterus.", "url": "https://disease-ontology.org/term/DOID:13223", "evidence": [ { "id": "13223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13223" } ], "weight": 0.0 }, { "disease_id": "DOID:2870", "name": "endometrial adenocarcinoma", "description": "An endometrial carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2870", "evidence": [ { "id": "2870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2870" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi cis cisterna membrane", "id": "GO:1990674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990674", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" }, { "name": "Golgi trans cisterna", "id": "GO:0000138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000138", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" }, { "name": "vesicle fusion with Golgi apparatus", "id": "GO:0048280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048280", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "P43682", "url": "https://www.uniprot.org/uniprotkb/P43682" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43682-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002101", "url": "https://www.yeastgenome.org/locus/S000002101" }, { "database": "iPTMnet", "id": "P43682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43682" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P43682-1" }, { "uniprot_canonical_ac": "P45818-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 564, "chemical_mass": 63653.0, "gene_names": "ROK1;G1651;ROK1", "protein_name": "ATP-dependent RNA helicase ROK1", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on RNA", "id": "GO:0008186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008186", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" } ], "biological_process": [ { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" }, { "name": "snoRNA localization", "id": "GO:0048254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048254", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P45818-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Thr168", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 168, "start_aa": "Thr", "end_pos": 168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr168", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P45818-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003139", "url": "https://www.yeastgenome.org/locus/S000003139" }, { "database": "iPTMnet", "id": "P45818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45818" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P45818-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003139", "url": "https://www.yeastgenome.org/locus/S000003139" }, { "database": "iPTMnet", "id": "P45818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45818" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P45818-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Thr68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003139", "url": "https://www.yeastgenome.org/locus/S000003139" }, { "database": "iPTMnet", "id": "P45818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45818" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P45818-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003139", "url": "https://www.yeastgenome.org/locus/S000003139" }, { "database": "iPTMnet", "id": "P45818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45818" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P45818-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Gly166", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "No cell growth and 2-fold decrease in ATPase activity in vitro.", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" }, { "database": "PubMed", "id": "10373593", "url": "https://glygen.org/publication/PubMed/10373593" } ] } ] }, { "uniprot_canonical_ac": "P45818-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Lys172", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "G", "comment": "Slow cell growth.", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" }, { "database": "PubMed", "id": "10373593", "url": "https://glygen.org/publication/PubMed/10373593" } ] }, { "sequence_org": "K", "sequence_mut": "L", "comment": "No cell growth and drastic decrease in ATPase activity in vitro.", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" }, { "database": "PubMed", "id": "10373593", "url": "https://glygen.org/publication/PubMed/10373593" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Slow cell growth.", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" }, { "database": "PubMed", "id": "10373593", "url": "https://glygen.org/publication/PubMed/10373593" } ] }, { "sequence_org": "K", "sequence_mut": "S", "comment": "Slow cell growth.", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" }, { "database": "PubMed", "id": "10373593", "url": "https://glygen.org/publication/PubMed/10373593" } ] }, { "sequence_org": "K", "sequence_mut": "W", "comment": "Slow cell growth.", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" }, { "database": "PubMed", "id": "10373593", "url": "https://glygen.org/publication/PubMed/10373593" } ] } ] }, { "uniprot_canonical_ac": "P45818-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Asp280", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Slow cell growth.", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" }, { "database": "PubMed", "id": "10373593", "url": "https://glygen.org/publication/PubMed/10373593" } ] }, { "sequence_org": "D", "sequence_mut": "V", "comment": "Slow cell growth.", "evidence": [ { "database": "UniProtKB", "id": "P45818", "url": "https://www.uniprot.org/uniprotkb/P45818" }, { "database": "PubMed", "id": "10373593", "url": "https://glygen.org/publication/PubMed/10373593" } ] } ] } ], "record_id": "P45818-1" }, { "uniprot_canonical_ac": "P45978-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P45978", "url": "https://www.uniprot.org/uniprotkb/P45978" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 349, "chemical_mass": 39190.0, "gene_names": "SCD6;LSM13;P9659.10;SCD6", "protein_name": "Protein SCD6", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P45978", "url": "https://www.uniprot.org/uniprotkb/P45978" } ], "pmid": "" }, { "name": "eukaryotic initiation factor 4G binding", "id": "GO:0031370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031370", "evidence": [ { "database": "UniProtKB", "id": "P45978", "url": "https://www.uniprot.org/uniprotkb/P45978" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P45978", "url": "https://www.uniprot.org/uniprotkb/P45978" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "P45978", "url": "https://www.uniprot.org/uniprotkb/P45978" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P45978", "url": "https://www.uniprot.org/uniprotkb/P45978" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of translational initiation", "id": "GO:0045947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045947", "evidence": [ { "database": "UniProtKB", "id": "P45978", "url": "https://www.uniprot.org/uniprotkb/P45978" } ], "pmid": "" }, { "name": "P-body assembly", "id": "GO:0033962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962", "evidence": [ { "database": "UniProtKB", "id": "P45978", "url": "https://www.uniprot.org/uniprotkb/P45978" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "P45978", "url": "https://www.uniprot.org/uniprotkb/P45978" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P45978-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Thr139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P45978", "url": "https://www.uniprot.org/uniprotkb/P45978" }, { "database": "PubMed", "id": "33856219", "url": "https://glygen.org/publication/PubMed/33856219" }, { "database": "SGD", "id": "S000006333", "url": "https://www.yeastgenome.org/locus/S000006333" }, { "database": "iPTMnet", "id": "P45978", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45978" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P45978-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Ser154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006333", "url": "https://www.yeastgenome.org/locus/S000006333" }, { "database": "iPTMnet", "id": "P45978", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45978" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P45978-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Thr155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006333", "url": "https://www.yeastgenome.org/locus/S000006333" }, { "database": "iPTMnet", "id": "P45978", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45978" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P45978-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Ser163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006333", "url": "https://www.yeastgenome.org/locus/S000006333" }, { "database": "iPTMnet", "id": "P45978", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45978" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P45978-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Ser165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006333", "url": "https://www.yeastgenome.org/locus/S000006333" }, { "database": "iPTMnet", "id": "P45978", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45978" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P45978-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006333", "url": "https://www.yeastgenome.org/locus/S000006333" }, { "database": "iPTMnet", "id": "P45978", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45978" }, { "database": "PubMed", "id": "33566094", "url": "https://glygen.org/publication/PubMed/33566094" } ] } ] }, { "uniprot_canonical_ac": "P45978-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Ser280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006333", "url": "https://www.yeastgenome.org/locus/S000006333" }, { "database": "iPTMnet", "id": "P45978", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45978" }, { "database": "PubMed", "id": "33566094", "url": "https://glygen.org/publication/PubMed/33566094" } ] } ] }, { "uniprot_canonical_ac": "P45978-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Ser287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006333", "url": "https://www.yeastgenome.org/locus/S000006333" }, { "database": "iPTMnet", "id": "P45978", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P45978" }, { "database": "PubMed", "id": "33566094", "url": "https://glygen.org/publication/PubMed/33566094" } ] } ] } ], "record_id": "P45978-1" }, { "uniprot_canonical_ac": "P46367-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 519, "chemical_mass": 56724.0, "gene_names": "ALD4;ALD4;ALD7;ALDH2;O6730", "protein_name": "Potassium-activated aldehyde dehydrogenase, mitochondrial", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0060841", "name": "isolated microphthalmia 8", "description": "An isolated microphthalmia characterized by bilateral severe microphthalmia autosomal recessive inheritance of that has_material_basis_in homozygous mutation in the ALDH1A3 gene on chromosome 15q26.", "url": "https://disease-ontology.org/term/DOID:0060841", "evidence": [ { "id": "0060841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060841" } ], "weight": 0.0 }, { "disease_id": "DOID:0070508", "name": "metabolic dysfunction and alcohol associated liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and elevated alcohol consumption. This disease is distinguished from MASLD by increased alcohol consumption and from ALD by the evidence of one or more of the specified cardiometabolic risk factors. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0070508", "evidence": [ { "id": "0070508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070508" } ], "weight": 0.0 }, { "disease_id": "DOID:0070658", "name": "alcohol-associated liver disease", "description": "A liver disease resulting from excessive alcohol intake.", "url": "https://disease-ontology.org/term/DOID:0070658", "evidence": [ { "id": "0070658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070658" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11198", "name": "DiGeorge syndrome", "description": "A syndrome that has_material_basis_in a large deletion of the chromosome 22q11.2 region which includes the DGS gene needed for development of the thymus and related glands with subsequent lack of T-cell production.", "url": "https://disease-ontology.org/term/DOID:11198", "evidence": [ { "id": "11198", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11198" } ], "weight": 0.0 }, { "disease_id": "DOID:114", "name": "heart disease", "description": "A cardiovascular system disease that involves the heart.", "url": "https://disease-ontology.org/term/DOID:114", "evidence": [ { "id": "114", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:114" } ], "weight": 0.0 }, { "disease_id": "DOID:14018", "name": "alcoholic liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:14018", "evidence": [ { "id": "14018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14018" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:3454", "name": "brain infarction", "description": "A cerebrovascular disease that is characterized by tissue necrosis located_in the brain, resulting from inadequate blood flow through the brain.", "url": "https://disease-ontology.org/term/DOID:3454", "evidence": [ { "id": "3454", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3454" } ], "weight": 0.0 }, { "disease_id": "DOID:3827", "name": "congenital diaphragmatic hernia", "description": "A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs.", "url": "https://disease-ontology.org/term/DOID:3827", "evidence": [ { "id": "3827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3827" } ], "weight": 0.0 }, { "disease_id": "DOID:409", "name": "liver disease", "description": "", "url": "https://disease-ontology.org/term/DOID:409", "evidence": [ { "id": "409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:409" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" } ], "pmid": "" }, { "name": "acetate biosynthetic process", "id": "GO:0019413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019413", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" } ], "pmid": "" }, { "name": "NADPH regeneration", "id": "GO:0006740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006740", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" } ], "pmid": "" }, { "name": "ethanol metabolic process", "id": "GO:0006067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006067", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" } ], "pmid": "" } ], "molecular_function": [ { "name": "aldehyde dehydrogenase (NAD+) activity", "id": "GO:0004029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004029", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" } ], "pmid": "" }, { "name": "aldehyde dehydrogenase [NAD(P)+] activity", "id": "GO:0004030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004030", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" } ], "pmid": "" }, { "name": "acetaldehyde dehydrogenase (NADP+) activity", "id": "GO:0140088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140088", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46367-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46367-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46367-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Thr216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" } ] } ] }, { "uniprot_canonical_ac": "P46367-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Thr267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46367-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46367-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Thr270", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46367-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Thr272", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46367-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Ser398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46367-1", "start_pos": "500", "end_pos": "500", "site_lbl": "Ser500", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46367-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46367", "url": "https://www.uniprot.org/uniprotkb/P46367" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46367-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005901", "url": "https://www.yeastgenome.org/locus/S000005901" }, { "database": "iPTMnet", "id": "P46367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P46367-1" }, { "uniprot_canonical_ac": "P46654-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46654", "url": "https://www.uniprot.org/uniprotkb/P46654" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 252, "chemical_mass": 27962.0, "gene_names": "RPS0B;L2118;NAB1B;NAB4;RPS0B;YST2", "protein_name": "Small ribosomal subunit protein uS2B", "disease": [ { "disease_id": "DOID:0110074", "name": "arrhythmogenic right ventricular dysplasia 5", "description": "An arrhythmogenic right ventricular dysplasia that has_material_basis_in heterozygous mutation in the TMEM43 gene on chromosome 3p25.", "url": "https://disease-ontology.org/term/DOID:0110074", "evidence": [ { "id": "0110074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110074" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:1339", "name": "Diamond-Blackfan anemia", "description": "A pure red-cell aplasia that is characterized by anemia (low red blood cell counts) with decreased erythroid progenitors in the bone marrow and has_material_basis_insufficient levels of red blood cells due to bone marrow dysfunction.", "url": "https://disease-ontology.org/term/DOID:1339", "evidence": [ { "id": "1339", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1339" } ], "weight": 0.0 }, { "disease_id": "DOID:9778", "name": "irritable bowel syndrome", "description": "An intestinal disease that is characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause.", "url": "https://disease-ontology.org/term/DOID:9778", "evidence": [ { "id": "9778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9778" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P46654", "url": "https://www.uniprot.org/uniprotkb/P46654" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P46654", "url": "https://www.uniprot.org/uniprotkb/P46654" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "P46654", "url": "https://www.uniprot.org/uniprotkb/P46654" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "P46654", "url": "https://www.uniprot.org/uniprotkb/P46654" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P46654", "url": "https://www.uniprot.org/uniprotkb/P46654" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000461", "evidence": [ { "database": "UniProtKB", "id": "P46654", "url": "https://www.uniprot.org/uniprotkb/P46654" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "P46654", "url": "https://www.uniprot.org/uniprotkb/P46654" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P46654", "url": "https://www.uniprot.org/uniprotkb/P46654" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46654-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004038", "url": "https://www.yeastgenome.org/locus/S000004038" }, { "database": "iPTMnet", "id": "P46654", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46654" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P46654-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46654", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46654" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] } ] }, { "uniprot_canonical_ac": "P46654-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46654", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46654" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P46654-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004038", "url": "https://www.yeastgenome.org/locus/S000004038" }, { "database": "iPTMnet", "id": "P46654", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46654" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46654-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Thr80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004038", "url": "https://www.yeastgenome.org/locus/S000004038" }, { "database": "iPTMnet", "id": "P46654", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46654" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P46654-1" }, { "uniprot_canonical_ac": "P46655-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 708, "chemical_mass": 80843.0, "gene_names": "GUS1;G0583;GSN1;GUS1;HRB724", "protein_name": "Glutamate--tRNA ligase, cytoplasmic", "disease": [ { "disease_id": "DOID:0070398", "name": "hypomyelinating leukodystrophy 15", "description": "A hypomyelinating leukodystrophy characterized by onset of motor and cognitive impairment of variable severity in the first or second decade of life that has_material_basis_in homozygous or compound heterozygous mutation in the EPRS1 gene on chromosome 1q41.", "url": "https://disease-ontology.org/term/DOID:0070398", "evidence": [ { "id": "0070398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070398" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "sequence-specific mRNA binding", "id": "GO:1990825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990825", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" }, { "name": "glutamate-tRNA ligase activity", "id": "GO:0004818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004818", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" }, { "name": "methionyl glutamyl tRNA synthetase complex", "id": "GO:0017102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017102", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" } ], "biological_process": [ { "name": "glutamyl-tRNA aminoacylation", "id": "GO:0006424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006424", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" }, { "name": "methionyl-tRNA aminoacylation", "id": "GO:0006431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006431", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46655-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Thr298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Thr300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Thr472", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "482", "end_pos": "482", "site_lbl": "Ser482", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "486", "end_pos": "486", "site_lbl": "Ser486", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Ser526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "591", "end_pos": "591", "site_lbl": "Ser591", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Ser640", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003214", "url": "https://www.yeastgenome.org/locus/S000003214" }, { "database": "iPTMnet", "id": "P46655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46655" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46655-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Arg148", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Abolishes interaction with ARC1.", "evidence": [ { "database": "UniProtKB", "id": "P46655", "url": "https://www.uniprot.org/uniprotkb/P46655" }, { "database": "PubMed", "id": "16914447", "url": "https://glygen.org/publication/PubMed/16914447" } ] } ] } ], "record_id": "P46655-1" }, { "uniprot_canonical_ac": "P46669-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 326, "chemical_mass": 36224.0, "gene_names": "RPA43;O6271;RPA43;RRN12", "protein_name": "DNA-directed RNA polymerase I subunit RPA43", "disease": [], "biological_process": [ { "name": "transcription by RNA polymerase I", "id": "GO:0006360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006360", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase I", "id": "GO:0006362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006362", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase I promoter", "id": "GO:0006361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006361", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" } ], "pmid": "" }, { "name": "termination of RNA polymerase I transcription", "id": "GO:0006363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006363", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" } ], "pmid": "" }, { "name": "nucleolar large rRNA transcription by RNA polymerase I", "id": "GO:0042790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042790", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" } ], "pmid": "" }, { "name": "RNA polymerase I complex", "id": "GO:0005736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005736", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46669-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Thr100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Ser208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "18084032", "url": "https://glygen.org/publication/PubMed/18084032" }, { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "18084032", "url": "https://glygen.org/publication/PubMed/18084032" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Ser244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Ser251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Tyr260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Ser262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "18084032", "url": "https://glygen.org/publication/PubMed/18084032" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Ser263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "18084032", "url": "https://glygen.org/publication/PubMed/18084032" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46669", "url": "https://www.uniprot.org/uniprotkb/P46669" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46669-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005867", "url": "https://www.yeastgenome.org/locus/S000005867" }, { "database": "iPTMnet", "id": "P46669", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46669" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P46669-1" }, { "uniprot_canonical_ac": "P46675-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 888, "chemical_mass": 100918.0, "gene_names": "STU2;L2108;STU2", "protein_name": "Protein STU2", "disease": [], "biological_process": [ { "name": "microtubule polymerization", "id": "GO:0046785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046785", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "microtubule plus-end directed mitotic chromosome migration", "id": "GO:0099606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099606", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "establishment or maintenance of microtubule cytoskeleton polarity", "id": "GO:0030951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030951", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "mitotic sister chromatid biorientation", "id": "GO:1990758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990758", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "repair of mitotic kinetochore microtubule attachment defect", "id": "GO:0140273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140273", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "microtubule plus-end binding", "id": "GO:0051010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051010", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" }, { "name": "microtubule plus end polymerase", "id": "GO:0061863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061863", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46675-1", "start_pos": "618", "end_pos": "618", "site_lbl": "Ser618", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 618, "start_aa": "Ser", "end_pos": 618, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser618", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P46675", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P46675" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Ser621", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 621, "start_aa": "Ser", "end_pos": 621, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser621", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P46675", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P46675" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "623", "end_pos": "623", "site_lbl": "Ser623", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 623, "start_aa": "Ser", "end_pos": 623, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser623", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P46675", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P46675" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Ser626", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 626, "start_aa": "Ser", "end_pos": 626, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser626", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P46675", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P46675" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Ser251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Ser280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Thr294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Thr300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Thr570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "576", "end_pos": "576", "site_lbl": "Thr576", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "602", "end_pos": "602", "site_lbl": "Ser602", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "603", "end_pos": "603", "site_lbl": "Ser603", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Ser684", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "740", "end_pos": "740", "site_lbl": "Ser740", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "787", "end_pos": "787", "site_lbl": "Ser787", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "812", "end_pos": "812", "site_lbl": "Ser812", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "813", "end_pos": "813", "site_lbl": "Ser813", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "815", "end_pos": "815", "site_lbl": "Ser815", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "825", "end_pos": "825", "site_lbl": "Ser825", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "866", "end_pos": "866", "site_lbl": "Thr866", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004035", "url": "https://www.yeastgenome.org/locus/S000004035" }, { "database": "iPTMnet", "id": "P46675", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46675" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Arg116", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreases interaction with tubulin heterodimer.", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" }, { "database": "PubMed", "id": "17355870", "url": "https://glygen.org/publication/PubMed/17355870" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Lys151", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Disrupts interaction with tubulin heterodimer.", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" }, { "database": "PubMed", "id": "17355870", "url": "https://glygen.org/publication/PubMed/17355870" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Arg200", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on polymerase activity under normal conditions but impairs polymerase activity under microtubule stress.", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" }, { "database": "PubMed", "id": "22904013", "url": "https://glygen.org/publication/PubMed/22904013" }, { "database": "PubMed", "id": "25097237", "url": "https://glygen.org/publication/PubMed/25097237" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Trp23", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Disrupts interaction with tubulin heterodimer. Impairs polymerase activity under microtubule stress.", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" }, { "database": "PubMed", "id": "22904013", "url": "https://glygen.org/publication/PubMed/22904013" }, { "database": "PubMed", "id": "17355870", "url": "https://glygen.org/publication/PubMed/17355870" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Trp341", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Disrupts interaction with tubulin heterodimer. Impairs polymerase activity under microtubule stress.", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" }, { "database": "PubMed", "id": "22904013", "url": "https://glygen.org/publication/PubMed/22904013" }, { "database": "PubMed", "id": "25097237", "url": "https://glygen.org/publication/PubMed/25097237" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "519", "end_pos": "519", "site_lbl": "Arg519", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Disrupts interaction with tubulin heterodimer. No effect on polymerase activity under normal conditions but impairs polymerase activity under microtubule stress.", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" }, { "database": "PubMed", "id": "22904013", "url": "https://glygen.org/publication/PubMed/22904013" }, { "database": "PubMed", "id": "25097237", "url": "https://glygen.org/publication/PubMed/25097237" } ] } ] }, { "uniprot_canonical_ac": "P46675-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Val69", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "D", "comment": "Impairs polymerase activity under microtubule stress.", "evidence": [ { "database": "UniProtKB", "id": "P46675", "url": "https://www.uniprot.org/uniprotkb/P46675" }, { "database": "PubMed", "id": "22904013", "url": "https://glygen.org/publication/PubMed/22904013" } ] } ] } ], "record_id": "P46675-1" }, { "uniprot_canonical_ac": "P46678-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 594, "chemical_mass": 67688.0, "gene_names": "BDP1;BDP1;N2682;TFC5;TFC7", "protein_name": "Transcription factor TFIIIB component B''", "disease": [ { "disease_id": "DOID:0111637", "name": "autosomal recessive nonsyndromic deafness 112", "description": "An autosomal recessive nonsyndromic deafness characterized by postlingual progressive sensorineural hearing impairment that has_material_basis_in homozygous or compound heterozygous mutation in the BDP1 gene on chromosome 5q13.2.", "url": "https://disease-ontology.org/term/DOID:0111637", "evidence": [ { "id": "0111637", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111637" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" } ], "pmid": "" }, { "name": "transcription factor TFIIIB complex", "id": "GO:0000126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000126", "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" } ], "pmid": "" }, { "name": "RNA polymerase III preinitiation complex assembly", "id": "GO:0070898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070898", "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase III", "id": "GO:0006359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006359", "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" } ], "pmid": "" }, { "name": "DNA-templated transcription open complex formation", "id": "GO:0001112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001112", "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" } ], "pmid": "" } ], "molecular_function": [ { "name": "TFIIIC-class transcription factor complex binding", "id": "GO:0001156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001156", "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46678-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004984", "url": "https://www.yeastgenome.org/locus/S000004984" }, { "database": "iPTMnet", "id": "P46678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46678" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P46678-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004984", "url": "https://www.yeastgenome.org/locus/S000004984" }, { "database": "iPTMnet", "id": "P46678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46678" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] } ] }, { "uniprot_canonical_ac": "P46678-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ser164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46678" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "25970584", "url": "https://glygen.org/publication/PubMed/25970584" }, { "database": "SGD", "id": "S000004984", "url": "https://www.yeastgenome.org/locus/S000004984" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46678-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Ser178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46678" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "25970584", "url": "https://glygen.org/publication/PubMed/25970584" }, { "database": "SGD", "id": "S000004984", "url": "https://www.yeastgenome.org/locus/S000004984" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P46678-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Thr26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004984", "url": "https://www.yeastgenome.org/locus/S000004984" }, { "database": "iPTMnet", "id": "P46678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46678" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P46678-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004984", "url": "https://www.yeastgenome.org/locus/S000004984" }, { "database": "iPTMnet", "id": "P46678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46678" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46678-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46678" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004984", "url": "https://www.yeastgenome.org/locus/S000004984" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46678-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46678", "url": "https://www.uniprot.org/uniprotkb/P46678" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46678" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "25970584", "url": "https://glygen.org/publication/PubMed/25970584" }, { "database": "SGD", "id": "S000004984", "url": "https://www.yeastgenome.org/locus/S000004984" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46678-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Ser586", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46678" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "25970584", "url": "https://glygen.org/publication/PubMed/25970584" }, { "database": "SGD", "id": "S000004984", "url": "https://www.yeastgenome.org/locus/S000004984" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46678-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46678", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46678" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004984", "url": "https://www.yeastgenome.org/locus/S000004984" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P46678-1" }, { "uniprot_canonical_ac": "P46680-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 615, "chemical_mass": 67326.0, "gene_names": "AIP1;AIP1;YM9582.17C", "protein_name": "Actin-interacting protein 1", "disease": [ { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" } ], "biological_process": [ { "name": "barbed-end actin filament capping", "id": "GO:0051016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051016", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" }, { "name": "negative regulation of cytokinesis", "id": "GO:0032466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032466", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" }, { "name": "actin filament depolymerization", "id": "GO:0030042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030042", "evidence": [ { "database": "UniProtKB", "id": "P46680", "url": "https://www.uniprot.org/uniprotkb/P46680" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46680-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004698", "url": "https://www.yeastgenome.org/locus/S000004698" }, { "database": "iPTMnet", "id": "P46680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46680" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46680-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46680" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004698", "url": "https://www.yeastgenome.org/locus/S000004698" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46680-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Tyr355", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004698", "url": "https://www.yeastgenome.org/locus/S000004698" }, { "database": "iPTMnet", "id": "P46680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46680" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46680-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004698", "url": "https://www.yeastgenome.org/locus/S000004698" }, { "database": "iPTMnet", "id": "P46680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46680" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P46680-1" }, { "uniprot_canonical_ac": "P46681-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46681", "url": "https://www.uniprot.org/uniprotkb/P46681" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 530, "chemical_mass": 59268.0, "gene_names": "DLD2;AIP2;DLD2", "protein_name": "D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2", "disease": [ { "disease_id": "DOID:0111351", "name": "D-2-hydroxyglutaric aciduria 1", "description": "A D-2-hydroxyglutaric aciduria that has_material_basis_in homozygous or compound heterozygous mutation in D2HGDH on 2q37.3.", "url": "https://disease-ontology.org/term/DOID:0111351", "evidence": [ { "id": "0111351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111351" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P46681", "url": "https://www.uniprot.org/uniprotkb/P46681" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "P46681", "url": "https://www.uniprot.org/uniprotkb/P46681" } ], "pmid": "" }, { "name": "D-lactate dehydrogenase (cytochrome) activity", "id": "GO:0004458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004458", "evidence": [ { "database": "UniProtKB", "id": "P46681", "url": "https://www.uniprot.org/uniprotkb/P46681" } ], "pmid": "" }, { "name": "(R)-2-hydroxyglutarate dehydrogenase activity", "id": "GO:0051990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051990", "evidence": [ { "database": "UniProtKB", "id": "P46681", "url": "https://www.uniprot.org/uniprotkb/P46681" } ], "pmid": "" }, { "name": "(R)-2-hydroxyglutarate-pyruvate transhydrogenase activity", "id": "GO:0099615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099615", "evidence": [ { "database": "UniProtKB", "id": "P46681", "url": "https://www.uniprot.org/uniprotkb/P46681" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P46681", "url": "https://www.uniprot.org/uniprotkb/P46681" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P46681", "url": "https://www.uniprot.org/uniprotkb/P46681" } ], "pmid": "" } ], "biological_process": [ { "name": "lactate catabolic process", "id": "GO:1903457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903457", "evidence": [ { "database": "UniProtKB", "id": "P46681", "url": "https://www.uniprot.org/uniprotkb/P46681" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46681-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002337", "url": "https://www.yeastgenome.org/locus/S000002337" }, { "database": "iPTMnet", "id": "P46681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46681" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P46681-1" }, { "uniprot_canonical_ac": "P46682-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 809, "chemical_mass": 91607.0, "gene_names": "APL6;APL6;G9331;YKS5", "protein_name": "AP-3 complex subunit beta", "disease": [ { "disease_id": "DOID:0060540", "name": "Hermansky-Pudlak syndrome 2", "description": "A Hermansky-Pudlak syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding the beta-3A subunit of the AP3 complex (AP3B1) on chromosome 5q14.1.", "url": "https://disease-ontology.org/term/DOID:0060540", "evidence": [ { "id": "0060540", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060540" } ], "weight": 0.0 }, { "disease_id": "DOID:0080448", "name": "developmental and epileptic encephalopathy 48", "description": "A developmental and epileptic encephalopathy characterized by seizure onset before 1 year of age, global developmental delay, intellectual disability, absent speech, and minimal or absent motor development that has_material_basis_in homozygous or compound heterozygous mutation in the AP3B2 gene on chromosome 15q25.", "url": "https://disease-ontology.org/term/DOID:0080448", "evidence": [ { "id": "0080448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080448" } ], "weight": 0.0 }, { "disease_id": "DOID:1227", "name": "neutropenia", "description": "", "url": "https://disease-ontology.org/term/DOID:1227", "evidence": [ { "id": "1227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1227" } ], "weight": 0.0 }, { "disease_id": "DOID:2223", "name": "platelet storage pool deficiency", "description": "", "url": "https://disease-ontology.org/term/DOID:2223", "evidence": [ { "id": "2223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2223" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:3753", "name": "Hermansky-Pudlak syndrome", "description": "A syndrome characterized by oculocutaneous albinism, bleeding problems due to platelet storage pool defect, visual impairment and lysosomal accumulation of ceroid lipofuscin.", "url": "https://disease-ontology.org/term/DOID:3753", "evidence": [ { "id": "3753", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3753" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" } ], "pmid": "" }, { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" } ], "pmid": "" }, { "name": "AP-3 adaptor complex", "id": "GO:0030123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030123", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46682-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Thr91", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 91, "start_aa": "Thr", "end_pos": 91, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr91", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P46682", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P46682" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "92", "end_pos": "92", "site_lbl": "Thr92", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 92, "start_aa": "Thr", "end_pos": 92, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr92", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P46682", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P46682" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Thr95", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 95, "start_aa": "Thr", "end_pos": 95, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr95", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P46682", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P46682" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Ser132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Ser209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Tyr215", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ser273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "639", "end_pos": "639", "site_lbl": "Ser639", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Thr652", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "693", "end_pos": "693", "site_lbl": "Ser693", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "695", "end_pos": "695", "site_lbl": "Ser695", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "696", "end_pos": "696", "site_lbl": "Ser696", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "698", "end_pos": "698", "site_lbl": "Ser698", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "704", "end_pos": "704", "site_lbl": "Ser704", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "707", "end_pos": "707", "site_lbl": "Ser707", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "709", "end_pos": "709", "site_lbl": "Thr709", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "711", "end_pos": "711", "site_lbl": "Ser711", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "712", "end_pos": "712", "site_lbl": "Ser712", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "717", "end_pos": "717", "site_lbl": "Thr717", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "724", "end_pos": "724", "site_lbl": "Ser724", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "726", "end_pos": "726", "site_lbl": "Ser726", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46682", "url": "https://www.uniprot.org/uniprotkb/P46682" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "735", "end_pos": "735", "site_lbl": "Thr735", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "748", "end_pos": "748", "site_lbl": "Ser748", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46682-1", "start_pos": "754", "end_pos": "754", "site_lbl": "Ser754", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003493", "url": "https://www.yeastgenome.org/locus/S000003493" }, { "database": "iPTMnet", "id": "P46682", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46682" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P46682-1" }, { "uniprot_canonical_ac": "P46943-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46943", "url": "https://www.uniprot.org/uniprotkb/P46943" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 645, "chemical_mass": 73188.0, "gene_names": "GUF1;GUF1;L8003.7", "protein_name": "Translation factor GUF1, mitochondrial", "disease": [ { "disease_id": "DOID:0050562", "name": "West syndrome", "description": "An infancy electroclinical syndrome that is characterized by infantile spasms, hypsarrhythmia on electroencephalogram and intellectual disability.", "url": "https://disease-ontology.org/term/DOID:0050562", "evidence": [ { "id": "0050562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050562" } ], "weight": 0.0 }, { "disease_id": "DOID:0080427", "name": "developmental and epileptic encephalopathy 40", "description": "A developmental and epileptic encephalopathy that has_material_basis_in homozygous or compound heterozygous mutation in the GUF1 gene on chromosome 4p12.", "url": "https://disease-ontology.org/term/DOID:0080427", "evidence": [ { "id": "0080427", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080427" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P46943", "url": "https://www.uniprot.org/uniprotkb/P46943" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P46943", "url": "https://www.uniprot.org/uniprotkb/P46943" } ], "pmid": "" }, { "name": "mitochondrial ribosome binding", "id": "GO:0097177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097177", "evidence": [ { "database": "UniProtKB", "id": "P46943", "url": "https://www.uniprot.org/uniprotkb/P46943" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P46943", "url": "https://www.uniprot.org/uniprotkb/P46943" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P46943", "url": "https://www.uniprot.org/uniprotkb/P46943" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P46943", "url": "https://www.uniprot.org/uniprotkb/P46943" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P46943", "url": "https://www.uniprot.org/uniprotkb/P46943" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P46943", "url": "https://www.uniprot.org/uniprotkb/P46943" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "P46943", "url": "https://www.uniprot.org/uniprotkb/P46943" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P46943-1" }, { "uniprot_canonical_ac": "P46944-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 698, "chemical_mass": 80495.0, "gene_names": "TRS85;GSG1;MUM1;TRS85;YD9727.04", "protein_name": "Trafficking protein particle complex III-specific subunit 85", "disease": [], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "Cvt vesicle assembly", "id": "GO:0071255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071255", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" }, { "name": "TRAPPIII protein complex", "id": "GO:1990072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990072", "evidence": [ { "database": "UniProtKB", "id": "P46944", "url": "https://www.uniprot.org/uniprotkb/P46944" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46944-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Ser360", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 360, "start_aa": "Ser", "end_pos": 360, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser360", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P46944", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P46944" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Thr365", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 365, "start_aa": "Thr", "end_pos": 365, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr365", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P46944", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P46944" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Ser111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "651", "end_pos": "651", "site_lbl": "Ser651", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "685", "end_pos": "685", "site_lbl": "Ser685", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "692", "end_pos": "692", "site_lbl": "Thr692", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "693", "end_pos": "693", "site_lbl": "Ser693", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "695", "end_pos": "695", "site_lbl": "Ser695", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Ser93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Thr96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46944-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46944", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46944" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002515", "url": "https://www.yeastgenome.org/locus/S000002515" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P46944-1" }, { "uniprot_canonical_ac": "P46947-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46947", "url": "https://www.uniprot.org/uniprotkb/P46947" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 266, "chemical_mass": 30472.0, "gene_names": "BUD13;BUD13;CWC26;G1642;SLC7", "protein_name": "Pre-mRNA-splicing factor CWC26", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P46947", "url": "https://www.uniprot.org/uniprotkb/P46947" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P46947", "url": "https://www.uniprot.org/uniprotkb/P46947" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "P46947", "url": "https://www.uniprot.org/uniprotkb/P46947" } ], "pmid": "" }, { "name": "RES complex", "id": "GO:0070274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070274", "evidence": [ { "database": "UniProtKB", "id": "P46947", "url": "https://www.uniprot.org/uniprotkb/P46947" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P46947", "url": "https://www.uniprot.org/uniprotkb/P46947" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "P46947", "url": "https://www.uniprot.org/uniprotkb/P46947" } ], "pmid": "" }, { "name": "maintenance of RNA location", "id": "GO:0051237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051237", "evidence": [ { "database": "UniProtKB", "id": "P46947", "url": "https://www.uniprot.org/uniprotkb/P46947" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46947-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003142", "url": "https://www.yeastgenome.org/locus/S000003142" }, { "database": "iPTMnet", "id": "P46947", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46947" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46947-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003142", "url": "https://www.yeastgenome.org/locus/S000003142" }, { "database": "iPTMnet", "id": "P46947", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46947" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P46947-1" }, { "uniprot_canonical_ac": "P46962-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 323, "chemical_mass": 37905.0, "gene_names": "CTK2;CTK2;J1390", "protein_name": "CTD kinase subunit beta", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "cyclin/CDK positive transcription elongation factor complex", "id": "GO:0008024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008024", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "CTDK-1 complex", "id": "GO:0070692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070692", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "positive regulation of translational fidelity", "id": "GO:0045903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045903", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription, elongation", "id": "GO:0032786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032786", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" } ], "molecular_function": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activator activity", "id": "GO:0061575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061575", "evidence": [ { "database": "UniProtKB", "id": "P46962", "url": "https://www.uniprot.org/uniprotkb/P46962" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P46962-1" }, { "uniprot_canonical_ac": "P46963-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 296, "chemical_mass": 34809.0, "gene_names": "CTK3;CTK3;YM8339.07", "protein_name": "CTD kinase subunit gamma", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" }, { "name": "CTDK-1 complex", "id": "GO:0070692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070692", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" }, { "name": "positive regulation of translational fidelity", "id": "GO:0045903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045903", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription, elongation", "id": "GO:0032786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032786", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" } ], "molecular_function": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46963-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ser159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Ser190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Thr24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Thr29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Thr34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Thr35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46963", "url": "https://www.uniprot.org/uniprotkb/P46963" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46963-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004580", "url": "https://www.yeastgenome.org/locus/S000004580" }, { "database": "iPTMnet", "id": "P46963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46963" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P46963-1" }, { "uniprot_canonical_ac": "P46971-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46971", "url": "https://www.uniprot.org/uniprotkb/P46971" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 762, "chemical_mass": 87966.0, "gene_names": "PMT4;J2176;PMT4", "protein_name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 4", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:0050560", "name": "Walker-Warburg syndrome", "description": "A congenital muscular dystrophy that is characterized by hypotonia, seizures, severe intellectual and developmental disability, eye abnormalities and early death and has_material_basis_in mutations in multiple genes including POMT1, POMT2, ISPD, FKTN, FKRP, and LARGE1.", "url": "https://disease-ontology.org/term/DOID:0050560", "evidence": [ { "id": "0050560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050560" } ], "weight": 0.0 }, { "disease_id": "DOID:0050588", "name": "muscular dystrophy-dystroglycanopathy type B1", "description": "A congenital muscular dystrophy characterized by muscle weakness, cognitive impairment and brain abnormalities and has_material_basis_in mutation to the POMT1 gene that encodes O-mannosyltransferase.", "url": "https://disease-ontology.org/term/DOID:0050588", "evidence": [ { "id": "0050588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050588" } ], "weight": 0.0 }, { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:0110297", "name": "autosomal recessive limb-girdle muscular dystrophy type 2K", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding protein O-mannosyltransferase (POMT1).", "url": "https://disease-ontology.org/term/DOID:0110297", "evidence": [ { "id": "0110297", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110297" } ], "weight": 0.0 }, { "disease_id": "DOID:0111237", "name": "congenital muscular dystrophy-dystroglycanopathy type A1", "description": "A congenital muscular dystrophy-dystroglycanopathy type A that has_material_basis_in homozygous or compound heterozygous mutation in POMT1 on 9q34.13.", "url": "https://disease-ontology.org/term/DOID:0111237", "evidence": [ { "id": "0111237", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111237" } ], "weight": 0.0 }, { "disease_id": "DOID:0112374", "name": "muscular dystrophy-dystroglycanopathy", "description": "A congenital muscular dystrophy characterized by muscular dystrophy resulting from defective glycosylation of dystroglycan.", "url": "https://disease-ontology.org/term/DOID:0112374", "evidence": [ { "id": "0112374", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112374" } ], "weight": 0.0 }, { "disease_id": "DOID:9296", "name": "cleft lip", "description": "An orofacial cleft that is characterized by a congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences.", "url": "https://disease-ontology.org/term/DOID:9296", "evidence": [ { "id": "9296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9296" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase activity", "id": "GO:0004169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004169", "evidence": [ { "database": "UniProtKB", "id": "P46971", "url": "https://www.uniprot.org/uniprotkb/P46971" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P46971", "url": "https://www.uniprot.org/uniprotkb/P46971" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P46971", "url": "https://www.uniprot.org/uniprotkb/P46971" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P46971", "url": "https://www.uniprot.org/uniprotkb/P46971" } ], "pmid": "" }, { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex", "id": "GO:0097586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097586", "evidence": [ { "database": "UniProtKB", "id": "P46971", "url": "https://www.uniprot.org/uniprotkb/P46971" } ], "pmid": "" } ], "biological_process": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "P46971", "url": "https://www.uniprot.org/uniprotkb/P46971" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "P46971", "url": "https://www.uniprot.org/uniprotkb/P46971" } ], "pmid": "" }, { "name": "regulation of endoplasmic reticulum unfolded protein response", "id": "GO:1900101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900101", "evidence": [ { "database": "UniProtKB", "id": "P46971", "url": "https://www.uniprot.org/uniprotkb/P46971" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46971-1", "start_pos": "759", "end_pos": "759", "site_lbl": "Asn759", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 759, "start_aa": "Asn", "end_pos": 759, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn759", "evidence": [ { "id": "P46971", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46971#ptm_processing" } ] } ] } ], "record_id": "P46971-1" }, { "uniprot_canonical_ac": "P46972-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 177, "chemical_mass": 19930.0, "gene_names": "IMP2;IMP2;YM9973.09", "protein_name": "Mitochondrial inner membrane protease subunit 2", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane peptidase complex", "id": "GO:0042720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042720", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" } ], "pmid": "" } ], "molecular_function": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" } ], "pmid": "" }, { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing involved in protein targeting to mitochondrion", "id": "GO:0006627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006627", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" } ], "pmid": "" }, { "name": "signal peptide processing", "id": "GO:0006465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006465", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46972-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Gly123", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "Reduces processing of cytochrome c1; no effect on presence of IMP1 and SOM1 in the IMP complex.", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" }, { "database": "PubMed", "id": "15118906", "url": "https://glygen.org/publication/PubMed/15118906" } ] } ] }, { "uniprot_canonical_ac": "P46972-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Asp124", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] }, { "sequence_org": "D", "sequence_mut": "Y", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] } ] }, { "uniprot_canonical_ac": "P46972-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Asp131", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] } ] }, { "uniprot_canonical_ac": "P46972-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] }, { "sequence_org": "S", "sequence_mut": "T", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] } ] }, { "uniprot_canonical_ac": "P46972-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Lys91", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "H", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] } ] }, { "uniprot_canonical_ac": "P46972-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Gly95", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Reduces processing of CYB2 and presence of IMP1 and SOM1 in the IMP complex.", "evidence": [ { "database": "UniProtKB", "id": "P46972", "url": "https://www.uniprot.org/uniprotkb/P46972" }, { "database": "PubMed", "id": "15118906", "url": "https://glygen.org/publication/PubMed/15118906" } ] } ] } ], "record_id": "P46972-1" }, { "uniprot_canonical_ac": "P46989-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 271, "chemical_mass": 30201.0, "gene_names": "ATG27;ATG27;ETF1;J0490", "protein_name": "Autophagy-related protein 27", "disease": [], "biological_process": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "vesicle organization", "id": "GO:0016050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016050", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P46989", "url": "https://www.uniprot.org/uniprotkb/P46989" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P46989-1" }, { "uniprot_canonical_ac": "P46990-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46990", "url": "https://www.uniprot.org/uniprotkb/P46990" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 184, "chemical_mass": 20551.0, "gene_names": "RPL17B;J0493;RPL17B;RPL20B", "protein_name": "Large ribosomal subunit protein uL22B", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P46990", "url": "https://www.uniprot.org/uniprotkb/P46990" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P46990", "url": "https://www.uniprot.org/uniprotkb/P46990" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P46990", "url": "https://www.uniprot.org/uniprotkb/P46990" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P46990", "url": "https://www.uniprot.org/uniprotkb/P46990" } ], "pmid": "" }, { "name": "cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000448", "evidence": [ { "database": "UniProtKB", "id": "P46990", "url": "https://www.uniprot.org/uniprotkb/P46990" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P46990", "url": "https://www.uniprot.org/uniprotkb/P46990" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46990-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Tyr113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003713", "url": "https://www.yeastgenome.org/locus/S000003713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003713", "url": "https://www.yeastgenome.org/locus/S000003713" }, { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Ser170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Tyr47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003713", "url": "https://www.yeastgenome.org/locus/S000003713" }, { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000003713", "url": "https://www.yeastgenome.org/locus/S000003713" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003713", "url": "https://www.yeastgenome.org/locus/S000003713" }, { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P46990-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46990", "url": "https://www.uniprot.org/uniprotkb/P46990" }, { "database": "SGD", "id": "S000003713", "url": "https://www.yeastgenome.org/locus/S000003713" }, { "database": "iPTMnet", "id": "P46990", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46990" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P46990-1" }, { "uniprot_canonical_ac": "P46995-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 733, "chemical_mass": 84461.0, "gene_names": "SET2;EZL1;J0520;KMT3;SET2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "disease": [ { "disease_id": "DOID:0050156", "name": "idiopathic pulmonary fibrosis", "description": "A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe.", "url": "https://disease-ontology.org/term/DOID:0050156", "evidence": [ { "id": "0050156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050156" } ], "weight": 0.0 }, { "disease_id": "DOID:0061043", "name": "autosomal dominant intellectual developmental disorder 70", "description": "An autosomal dominant intellectual developmental disorder characterized by mild global developmental delay, moderately impaired intellectual disability with speech difficulties, and behavioral abnormalities that has_material_basis_in a specific heterozygous missense mutation (R1740Q) in the SETD2 gene on chromosome 3p21.", "url": "https://disease-ontology.org/term/DOID:0061043", "evidence": [ { "id": "0061043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061043" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1790", "name": "malignant mesothelioma", "description": "A cell type cancer that has_material_basis_in mesothelial tissue that develops from the thin layer of tissue that covers many of the internal organs. Exposure to airborne asbestos particles increases one's risk of developing malignant mesothelioma.", "url": "https://disease-ontology.org/term/DOID:1790", "evidence": [ { "id": "1790", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1790" } ], "weight": 0.0 }, { "disease_id": "DOID:3571", "name": "liver cancer", "description": "A hepatobiliary system cancer that is located_in the liver.", "url": "https://disease-ontology.org/term/DOID:3571", "evidence": [ { "id": "3571", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3571" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4467", "name": "clear cell renal cell carcinoma", "description": "A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope.", "url": "https://disease-ontology.org/term/DOID:4467", "evidence": [ { "id": "4467", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4467" } ], "weight": 0.0 }, { "disease_id": "DOID:7474", "name": "malignant pleural mesothelioma", "description": "A pleural cancer that has_material_basis_in mesothelium cells.", "url": "https://disease-ontology.org/term/DOID:7474", "evidence": [ { "id": "7474", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7474" } ], "weight": 0.0 }, { "disease_id": "DOID:9253", "name": "gastrointestinal stromal tumor", "description": "", "url": "https://disease-ontology.org/term/DOID:9253", "evidence": [ { "id": "9253", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9253" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "DNA-templated transcription termination", "id": "GO:0006353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006353", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "transcription-coupled nucleotide-excision repair", "id": "GO:0006283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006283", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "negative regulation of reciprocal meiotic recombination", "id": "GO:0045128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045128", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "DNA-templated transcription elongation", "id": "GO:0006354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006354", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "sno(s)RNA transcription", "id": "GO:0009302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009302", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "ascospore formation", "id": "GO:0030437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030437", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "negative regulation of antisense RNA transcription", "id": "GO:0060195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060195", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "histone H3K36 methyltransferase activity", "id": "GO:0046975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046975", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "histone H3K36 trimethyltransferase activity", "id": "GO:0140955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140955", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P46995-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Thr127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "12381723", "url": "https://glygen.org/publication/PubMed/12381723" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Thr429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "516", "end_pos": "516", "site_lbl": "Ser516", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Thr518", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Ser522", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "524", "end_pos": "524", "site_lbl": "Ser524", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Ser526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Thr531", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "543", "end_pos": "543", "site_lbl": "Ser543", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "572", "end_pos": "572", "site_lbl": "Ser572", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Ser585", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "718", "end_pos": "718", "site_lbl": "Ser718", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "719", "end_pos": "719", "site_lbl": "Ser719", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "721", "end_pos": "721", "site_lbl": "Ser721", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "726", "end_pos": "726", "site_lbl": "Ser726", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P46995", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46995" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "SGD", "id": "S000003704", "url": "https://www.yeastgenome.org/locus/S000003704" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Arg195", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "G", "comment": "Reduces dramatically histone methyltransferase activity toward nucleosomes.", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" }, { "database": "PubMed", "id": "11839797", "url": "https://glygen.org/publication/PubMed/11839797" } ] } ] }, { "uniprot_canonical_ac": "P46995-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Cys201", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Reduces dramatically histone methyltransferase activity toward nucleosomes.", "evidence": [ { "database": "UniProtKB", "id": "P46995", "url": "https://www.uniprot.org/uniprotkb/P46995" }, { "database": "PubMed", "id": "11839797", "url": "https://glygen.org/publication/PubMed/11839797" } ] } ] } ], "record_id": "P46995-1" }, { "uniprot_canonical_ac": "P47001-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 227, "chemical_mass": 23242.0, "gene_names": "CIS3;CCW11;CCW5;CIS3;J0561;PIR4;SCW8", "protein_name": "Cell wall mannoprotein CIS3", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of cell wall", "id": "GO:0005199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005199", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" } ], "pmid": "" } ], "biological_process": [ { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47001-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 105, "start_aa": "Ser", "end_pos": 105, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser105", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "12776183", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12776183" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 106, "start_aa": "Ser", "end_pos": 106, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser106", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "12776183", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12776183" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 107, "start_aa": "Ser", "end_pos": 107, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser107", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "12776183", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12776183" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 109, "start_aa": "Ser", "end_pos": 109, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser109", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "12776183", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12776183" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Thr111", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 111, "start_aa": "Thr", "end_pos": 111, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr111", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "12776183", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12776183" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 112, "start_aa": "Ser", "end_pos": 112, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser112", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "12776183", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12776183" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Thr113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 113, "start_aa": "Thr", "end_pos": 113, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr113", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "12776183", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12776183" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Asn114", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 114, "start_aa": "Asn", "end_pos": 114, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn114", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Thr116", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 116, "start_aa": "Thr", "end_pos": 116, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr116", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "12776183", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12776183" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 117, "start_aa": "Ser", "end_pos": 117, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser117", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "12776183", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12776183" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 118, "start_aa": "Ser", "end_pos": 118, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser118", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "12776183", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12776183" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Thr122", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 122, "start_aa": "Thr", "end_pos": 122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 68, "start_aa": "Ser", "end_pos": 68, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser68", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "16495216", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Does not affect cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "16495216", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Thr78", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 78, "start_aa": "Thr", "end_pos": 78, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr78", "evidence": [ { "id": "P47001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47001#ptm_processing" }, { "id": "16495216", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Does not affect cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "16495216", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Ser154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47001" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003694", "url": "https://www.yeastgenome.org/locus/S000003694" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Thr93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47001", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47001" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003694", "url": "https://www.yeastgenome.org/locus/S000003694" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Cys130", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Does not affect cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "12898712", "url": "https://glygen.org/publication/PubMed/12898712" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Cys197", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Results in the incorporation of KEX2-unprocessed precursor protein into the cell wall.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "12898712", "url": "https://glygen.org/publication/PubMed/12898712" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Cys227", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "", "comment": "Does not affect cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "12898712", "url": "https://glygen.org/publication/PubMed/12898712" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Asp65", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Does not affect cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "16495216", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Gln69", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Results in complete loss of cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "16495216", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Asp72", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Results in complete loss of cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "16495216", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Gln74", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Results in complete loss of cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "16495216", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Gln76", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Results in complete loss of cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "16495216", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Does not affect cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "16495216", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ] }, { "uniprot_canonical_ac": "P47001-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Thr82", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Does not affect cell wall incorporation.", "evidence": [ { "database": "UniProtKB", "id": "P47001", "url": "https://www.uniprot.org/uniprotkb/P47001" }, { "database": "PubMed", "id": "16495216", "url": "https://glygen.org/publication/PubMed/16495216" } ] } ] } ], "record_id": "P47001-1" }, { "uniprot_canonical_ac": "P47002-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 699, "chemical_mass": 77527.0, "gene_names": "SSY5;APF8;J0570;RAA3;SSY5", "protein_name": "SPS-sensor serine protease component SSY5", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" } ], "pmid": "" }, { "name": "protein autoprocessing", "id": "GO:0016540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016540", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" } ], "pmid": "" }, { "name": "response to amino acid", "id": "GO:0043200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043200", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47002-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003692", "url": "https://www.yeastgenome.org/locus/S000003692" }, { "database": "iPTMnet", "id": "P47002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47002" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003692", "url": "https://www.yeastgenome.org/locus/S000003692" }, { "database": "iPTMnet", "id": "P47002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47002" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "422", "end_pos": "422", "site_lbl": "Ser422", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47002" }, { "database": "PubMed", "id": "31461372", "url": "https://glygen.org/publication/PubMed/31461372" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Ser424", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47002" }, { "database": "PubMed", "id": "31461372", "url": "https://glygen.org/publication/PubMed/31461372" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Ser426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47002" }, { "database": "PubMed", "id": "31461372", "url": "https://glygen.org/publication/PubMed/31461372" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Thr80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47002" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003692", "url": "https://www.yeastgenome.org/locus/S000003692" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Glu131", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "In SSY5-13; constitutively active, confers 9.3% increased STP1 processing in the absence of amino acids.", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" }, { "database": "PubMed", "id": "16524914", "url": "https://glygen.org/publication/PubMed/16524914" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "512", "end_pos": "512", "site_lbl": "Glu512", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "In SSY5-6; constitutively active, confers 30% increased STP1 processing in the absence of amino acids.", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" }, { "database": "PubMed", "id": "15947203", "url": "https://glygen.org/publication/PubMed/15947203" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Phe575", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "V", "comment": "In SSY5-14; constitutively active, confers 30% increased STP1 processing in the absence of amino acids.", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" }, { "database": "PubMed", "id": "16524914", "url": "https://glygen.org/publication/PubMed/16524914" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "576", "end_pos": "576", "site_lbl": "Gln576", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "P", "comment": "In SSY5-15; constitutively active, confers 30% increased STP1 processing in the absence of amino acids.", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" }, { "database": "PubMed", "id": "16524914", "url": "https://glygen.org/publication/PubMed/16524914" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "581", "end_pos": "581", "site_lbl": "Lys581", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "N", "comment": "In SSY5-18; constitutively active, confers 15.5% increased STP1 processing in the absence of amino acids; when associated with H-632.", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" }, { "database": "PubMed", "id": "16524914", "url": "https://glygen.org/publication/PubMed/16524914" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Pro632", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "H", "comment": "In SSY5-18; constitutively active, confers 15.5% increased STP1 processing in the absence of amino acids; when associated with N-581.", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" }, { "database": "PubMed", "id": "16524914", "url": "https://glygen.org/publication/PubMed/16524914" } ] } ] }, { "uniprot_canonical_ac": "P47002-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Ser640", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Impairs maturation and amino acid-induced STP1 cleavage.", "evidence": [ { "database": "UniProtKB", "id": "P47002", "url": "https://www.uniprot.org/uniprotkb/P47002" }, { "database": "PubMed", "id": "15509782", "url": "https://glygen.org/publication/PubMed/15509782" } ] } ] } ], "record_id": "P47002-1" }, { "uniprot_canonical_ac": "P47005-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47005", "url": "https://www.uniprot.org/uniprotkb/P47005" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 663, "chemical_mass": 77367.0, "gene_names": "DAS1;DAS1;DUH1;J0634", "protein_name": "F-box protein DAS1", "disease": [], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P47005", "url": "https://www.uniprot.org/uniprotkb/P47005" } ], "pmid": "" } ], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "P47005", "url": "https://www.uniprot.org/uniprotkb/P47005" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P47005", "url": "https://www.uniprot.org/uniprotkb/P47005" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P47005", "url": "https://www.uniprot.org/uniprotkb/P47005" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "P47005", "url": "https://www.uniprot.org/uniprotkb/P47005" } ], "pmid": "" }, { "name": "regulation of transcription by galactose", "id": "GO:0000409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000409", "evidence": [ { "database": "UniProtKB", "id": "P47005", "url": "https://www.uniprot.org/uniprotkb/P47005" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47005-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003685", "url": "https://www.yeastgenome.org/locus/S000003685" }, { "database": "iPTMnet", "id": "P47005", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47005" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47005-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003685", "url": "https://www.yeastgenome.org/locus/S000003685" }, { "database": "iPTMnet", "id": "P47005", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47005" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P47005-1" }, { "uniprot_canonical_ac": "P47006-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 233, "chemical_mass": 26875.0, "gene_names": "RPA34;CST21;J0637;RPA34", "protein_name": "DNA-directed RNA polymerase I subunit RPA34", "disease": [], "biological_process": [ { "name": "transcription by RNA polymerase I", "id": "GO:0006360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006360", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase I", "id": "GO:0006362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006362", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase I promoter", "id": "GO:0006361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006361", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "pmid": "" }, { "name": "termination of RNA polymerase I transcription", "id": "GO:0006363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006363", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "pmid": "" }, { "name": "nucleolar large rRNA transcription by RNA polymerase I", "id": "GO:0042790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042790", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "pmid": "" }, { "name": "RNA polymerase I complex", "id": "GO:0005736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005736", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47006-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "18084032", "url": "https://glygen.org/publication/PubMed/18084032" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "18084032", "url": "https://glygen.org/publication/PubMed/18084032" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Ser140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47006", "url": "https://www.uniprot.org/uniprotkb/P47006" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47006-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Tyr8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47006" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003684", "url": "https://www.yeastgenome.org/locus/S000003684" } ] } ] } ], "record_id": "P47006-1" }, { "uniprot_canonical_ac": "P47008-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 294, "chemical_mass": 34388.0, "gene_names": "SFH5;J0644;SFH5", "protein_name": "Phosphatidylinositol transfer protein SFH5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "cortical endoplasmic reticulum", "id": "GO:0032541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032541", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "phosphatidylinositol transfer activity", "id": "GO:0008526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008526", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "regulation of establishment of cell polarity", "id": "GO:2000114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000114", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" }, { "name": "regulation of exocytosis", "id": "GO:0017157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017157", "evidence": [ { "database": "UniProtKB", "id": "P47008", "url": "https://www.uniprot.org/uniprotkb/P47008" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P47008-1" }, { "uniprot_canonical_ac": "P47011-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47011", "url": "https://www.uniprot.org/uniprotkb/P47011" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 380, "chemical_mass": 44546.0, "gene_names": "GLG2;GLG2;J0663", "protein_name": "Glycogenin-2", "disease": [ { "disease_id": "DOID:0050579", "name": "glycogen storage disease XV", "description": "A glycogen storage disease characterized by muscle weakness and cardiac abnormalities caused and has_material_basis_in mutation in the GYG1 gene that encodes glycogenin-1.", "url": "https://disease-ontology.org/term/DOID:0050579", "evidence": [ { "id": "0050579", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050579" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "glycogenin glucosyltransferase activity", "id": "GO:0008466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008466", "evidence": [ { "database": "UniProtKB", "id": "P47011", "url": "https://www.uniprot.org/uniprotkb/P47011" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P47011", "url": "https://www.uniprot.org/uniprotkb/P47011" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47011", "url": "https://www.uniprot.org/uniprotkb/P47011" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "P47011", "url": "https://www.uniprot.org/uniprotkb/P47011" } ], "pmid": "" } ], "biological_process": [ { "name": "glycogen biosynthetic process", "id": "GO:0005978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005978", "evidence": [ { "database": "UniProtKB", "id": "P47011", "url": "https://www.uniprot.org/uniprotkb/P47011" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47011-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Tyr230", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-glucosylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "Y", "relation": "attached", "comment": "O-linked (Glc...) tyrosine;O-glucosylation", "icn3d_view": {}, "start_pos": 230, "start_aa": "Tyr", "end_pos": 230, "end_aa": "Tyr", "residue": "Tyr", "site_lbl": "Tyr230", "evidence": [ { "id": "P47011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47011#ptm_processing" }, { "id": "15479227", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/15479227" } ] } ], "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Eliminates glycogen accumulation; when associated with F-232 and F-367.", "evidence": [ { "database": "UniProtKB", "id": "P47011", "url": "https://www.uniprot.org/uniprotkb/P47011" }, { "database": "PubMed", "id": "8900126", "url": "https://glygen.org/publication/PubMed/8900126" } ] } ] }, { "uniprot_canonical_ac": "P47011-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Tyr232", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-glucosylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "Y", "relation": "attached", "comment": "O-linked (Glc...) tyrosine;O-glucosylation", "icn3d_view": {}, "start_pos": 232, "start_aa": "Tyr", "end_pos": 232, "end_aa": "Tyr", "residue": "Tyr", "site_lbl": "Tyr232", "evidence": [ { "id": "P47011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47011#ptm_processing" }, { "id": "15479227", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/15479227" } ] } ], "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Eliminates glycogen accumulation; when associated with F-230 and F-367.", "evidence": [ { "database": "UniProtKB", "id": "P47011", "url": "https://www.uniprot.org/uniprotkb/P47011" }, { "database": "PubMed", "id": "8900126", "url": "https://glygen.org/publication/PubMed/8900126" } ] } ] }, { "uniprot_canonical_ac": "P47011-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Tyr367", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-glucosylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "Y", "relation": "attached", "comment": "O-linked (Glc...) tyrosine;O-glucosylation", "icn3d_view": {}, "start_pos": 367, "start_aa": "Tyr", "end_pos": 367, "end_aa": "Tyr", "residue": "Tyr", "site_lbl": "Tyr367", "evidence": [ { "id": "P47011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47011#ptm_processing" } ] } ], "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Eliminates glycogen accumulation; when associated with F-230 and F-232.", "evidence": [ { "database": "UniProtKB", "id": "P47011", "url": "https://www.uniprot.org/uniprotkb/P47011" }, { "database": "PubMed", "id": "8900126", "url": "https://glygen.org/publication/PubMed/8900126" } ] } ] } ], "record_id": "P47011-1" }, { "uniprot_canonical_ac": "P47013-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 409, "chemical_mass": 47372.0, "gene_names": "LCB3;J0671;LBP1;LCB3;YSR2", "protein_name": "Dihydrosphingosine 1-phosphate phosphatase LCB3", "disease": [], "molecular_function": [ { "name": "dihydrosphingosine-1-phosphate phosphatase activity", "id": "GO:0070780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070780", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" } ], "pmid": "" }, { "name": "sphingosine-1-phosphate phosphatase activity", "id": "GO:0042392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042392", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" } ], "pmid": "" }, { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47013-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Thr16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47013" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003670", "url": "https://www.yeastgenome.org/locus/S000003670" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47013-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P47013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47013" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003670", "url": "https://www.yeastgenome.org/locus/S000003670" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47013-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Tyr28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47013" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003670", "url": "https://www.yeastgenome.org/locus/S000003670" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47013-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Thr337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003670", "url": "https://www.yeastgenome.org/locus/S000003670" }, { "database": "iPTMnet", "id": "P47013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47013" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47013-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003670", "url": "https://www.yeastgenome.org/locus/S000003670" }, { "database": "iPTMnet", "id": "P47013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47013" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P47013-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Thr7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003670", "url": "https://www.yeastgenome.org/locus/S000003670" }, { "database": "iPTMnet", "id": "P47013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47013" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47013-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003670", "url": "https://www.yeastgenome.org/locus/S000003670" }, { "database": "iPTMnet", "id": "P47013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47013" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47013-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Lys128", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Impairs dihydrosphingosine 1-phosphate phosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" }, { "database": "PubMed", "id": "12786943", "url": "https://glygen.org/publication/PubMed/12786943" } ] } ] }, { "uniprot_canonical_ac": "P47013-1", "start_pos": "160", "end_pos": "160", "site_lbl": "His160", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Impairs dihydrosphingosine 1-phosphate phosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" }, { "database": "PubMed", "id": "12786943", "url": "https://glygen.org/publication/PubMed/12786943" } ] } ] }, { "uniprot_canonical_ac": "P47013-1", "start_pos": "210", "end_pos": "210", "site_lbl": "His210", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Impairs dihydrosphingosine 1-phosphate phosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "P47013", "url": "https://www.uniprot.org/uniprotkb/P47013" }, { "database": "PubMed", "id": "12786943", "url": "https://glygen.org/publication/PubMed/12786943" } ] } ] } ], "record_id": "P47013-1" }, { "uniprot_canonical_ac": "P47016-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47016", "url": "https://www.uniprot.org/uniprotkb/P47016" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 307, "chemical_mass": 34693.0, "gene_names": "NIT2;J0706;NIT2", "protein_name": "Deaminated glutathione amidase", "disease": [ { "disease_id": "DOID:0061234", "name": "brain small vessel disease 4", "description": "A brain small vessel disease characterized by schemic and/or hemorrhagic events in the brain that result in neurologic symptoms and deficits, progressive movement disorders, gait abnormalities, dysarthria, and cognitive decline that has_material_basis_in homozygous or compound heterozygous mutation in the NIT1 gene on chromosome 1q23.", "url": "https://disease-ontology.org/term/DOID:0061234", "evidence": [ { "id": "0061234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061234" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P47016", "url": "https://www.uniprot.org/uniprotkb/P47016" } ], "pmid": "" } ], "biological_process": [ { "name": "amide catabolic process", "id": "GO:0043605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043605", "evidence": [ { "database": "UniProtKB", "id": "P47016", "url": "https://www.uniprot.org/uniprotkb/P47016" } ], "pmid": "" } ], "molecular_function": [ { "name": "[acetyl-CoA carboxylase]-phosphatase activity", "id": "GO:0050406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050406", "evidence": [ { "database": "UniProtKB", "id": "P47016", "url": "https://www.uniprot.org/uniprotkb/P47016" } ], "pmid": "" }, { "name": "deaminated glutathione amidase activity", "id": "GO:0110050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110050", "evidence": [ { "database": "UniProtKB", "id": "P47016", "url": "https://www.uniprot.org/uniprotkb/P47016" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47016-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003662", "url": "https://www.yeastgenome.org/locus/S000003662" }, { "database": "iPTMnet", "id": "P47016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47016" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47016-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003662", "url": "https://www.yeastgenome.org/locus/S000003662" }, { "database": "iPTMnet", "id": "P47016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47016" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47016-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Cys169", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P47016", "url": "https://www.uniprot.org/uniprotkb/P47016" }, { "database": "PubMed", "id": "23897470", "url": "https://glygen.org/publication/PubMed/23897470" } ] } ] } ], "record_id": "P47016-1" }, { "uniprot_canonical_ac": "P47024-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1803, "chemical_mass": 207710.0, "gene_names": "TY4B-J;J0780;YJLWTy4-1 POL", "protein_name": "Transposon Ty4-J Gag-Pol polyprotein", "disease": [], "molecular_function": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "transposition", "id": "GO:0032196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032196", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" }, { "name": "viral translational frameshifting", "id": "GO:0075523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075523", "evidence": [ { "database": "UniProtKB", "id": "P47024", "url": "https://www.uniprot.org/uniprotkb/P47024" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47024-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Thr544", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 544, "start_aa": "Thr", "end_pos": 544, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr544", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] } ], "record_id": "P47024-1" }, { "uniprot_canonical_ac": "P47025-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 714, "chemical_mass": 80032.0, "gene_names": "MDV1;FIS2;GAG3;J0802;MDV1;NET2", "protein_name": "Mitochondrial division protein 1", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" } ], "pmid": "" } ], "biological_process": [ { "name": "peroxisome fission", "id": "GO:0016559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016559", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fission", "id": "GO:0090141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090141", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47025-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Ser222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Ser318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Ser337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Ser343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Ser358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Ser376", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Thr379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Thr523", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" }, { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Thr55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47025", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47025" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003648", "url": "https://www.yeastgenome.org/locus/S000003648" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Leu148", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "Abolishes interaction with FIS1.", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "16272155", "url": "https://glygen.org/publication/PubMed/16272155" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Glu250", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "G", "comment": "Suppresses the mitochondrial fission defect of a FIS1-3 mutant by affecting interaction with FIS1.", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "16247028", "url": "https://glygen.org/publication/PubMed/16247028" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Phe400", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "No interaction with FIS1; slight decrease in interaction with DNM1.", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "14517324", "url": "https://glygen.org/publication/PubMed/14517324" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "440", "end_pos": "440", "site_lbl": "His440", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "E", "comment": "Abolishes interaction with DNM1.", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "16272155", "url": "https://glygen.org/publication/PubMed/16272155" } ] }, { "sequence_org": "H", "sequence_mut": "N", "comment": "Abolishes interaction with DNM1.", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "16272155", "url": "https://glygen.org/publication/PubMed/16272155" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Arg461", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Slight decrease in interaction with FIS1; 20-fold decrease in interaction with DNM1; even distribution along mitochondria not punctate.", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "14517324", "url": "https://glygen.org/publication/PubMed/14517324" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Asn544", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "R", "comment": "Results in mitochondrial division defect, but has no effect on the interaction with DNM1.", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "16272155", "url": "https://glygen.org/publication/PubMed/16272155" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "605", "end_pos": "605", "site_lbl": "His605", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "E", "comment": "Abolishes interaction with DNM1.", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "16272155", "url": "https://glygen.org/publication/PubMed/16272155" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "664", "end_pos": "664", "site_lbl": "Asp664", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Slight decrease in interaction with DNM1.", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "14517324", "url": "https://glygen.org/publication/PubMed/14517324" } ] } ] }, { "uniprot_canonical_ac": "P47025-1", "start_pos": "689", "end_pos": "689", "site_lbl": "Ser689", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Slight decrease in interaction with DNM1.", "evidence": [ { "database": "UniProtKB", "id": "P47025", "url": "https://www.uniprot.org/uniprotkb/P47025" }, { "database": "PubMed", "id": "14517324", "url": "https://glygen.org/publication/PubMed/14517324" } ] } ] } ], "record_id": "P47025-1" }, { "uniprot_canonical_ac": "P47026-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 490, "chemical_mass": 55466.0, "gene_names": "GWT1;GWT1;J0916", "protein_name": "GPI-anchored wall transfer protein 1", "disease": [ { "disease_id": "DOID:0070432", "name": "hyperphosphatasia with impaired intellectual development syndrome 5", "description": "A hyperphosphatasia with impaired intellectual development syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the PIGW gene on chromosome 17q12.", "url": "https://disease-ontology.org/term/DOID:0070432", "evidence": [ { "id": "0070432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070432" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" } ], "pmid": "" }, { "name": "nuclear outer membrane-endoplasmic reticulum membrane network", "id": "GO:0042175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042175", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" } ], "pmid": "" } ], "biological_process": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" } ], "pmid": "" } ], "molecular_function": [ { "name": "glucosaminyl-phosphatidylinositol O-acyltransferase activity", "id": "GO:0032216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032216", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47026-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Gly132", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "Resistant to the drug 1-[4-butylbenzyl]isoquinoline (BIQ).", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" }, { "database": "PubMed", "id": "12753194", "url": "https://glygen.org/publication/PubMed/12753194" } ] } ] }, { "uniprot_canonical_ac": "P47026-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Leu209", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "In gwt1-28; temperature sensitive mutant that induces a delay in export of GPI-anchored proteins; when associated with D-259.", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" }, { "database": "PubMed", "id": "12714589", "url": "https://glygen.org/publication/PubMed/12714589" } ] } ] }, { "uniprot_canonical_ac": "P47026-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Val259", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "D", "comment": "In gwt1-28; temperature sensitive mutant that induces a delay in export of GPI-anchored proteins; when associated with P-209.", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" }, { "database": "PubMed", "id": "12714589", "url": "https://glygen.org/publication/PubMed/12714589" } ] } ] }, { "uniprot_canonical_ac": "P47026-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Asn330", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "S", "comment": "In gwt1-16; temperature sensitive mutant that induces a delay in export of GPI-anchored proteins; when associated with P-362 and A-479.", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" }, { "database": "PubMed", "id": "12714589", "url": "https://glygen.org/publication/PubMed/12714589" } ] } ] }, { "uniprot_canonical_ac": "P47026-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Leu362", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "In gwt1-16; temperature sensitive mutant that induces a delay in export of GPI-anchored proteins; when associated with S-330 and A-479.", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" }, { "database": "PubMed", "id": "12714589", "url": "https://glygen.org/publication/PubMed/12714589" } ] } ] }, { "uniprot_canonical_ac": "P47026-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Val397", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "I", "comment": "Resistant to the drug 1-[4-butylbenzyl]isoquinoline (BIQ).", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" }, { "database": "PubMed", "id": "12753194", "url": "https://glygen.org/publication/PubMed/12753194" } ] } ] }, { "uniprot_canonical_ac": "P47026-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Val479", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "In gwt1-16; temperature sensitive mutant that induces a delay in export of GPI-anchored proteins; when associated with S-330 and P-362.", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" }, { "database": "PubMed", "id": "12714589", "url": "https://glygen.org/publication/PubMed/12714589" } ] } ] }, { "uniprot_canonical_ac": "P47026-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Lys8", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "In gwt1-10; impairs the transport of detergent-resistant microdomain-associated membrane proteins TAT2 and FUR4.", "evidence": [ { "database": "UniProtKB", "id": "P47026", "url": "https://www.uniprot.org/uniprotkb/P47026" }, { "database": "PubMed", "id": "16361252", "url": "https://glygen.org/publication/PubMed/16361252" } ] } ] } ], "record_id": "P47026-1" }, { "uniprot_canonical_ac": "P47029-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1046, "chemical_mass": 117216.0, "gene_names": "ALY2;ALY2;ART3;J0934", "protein_name": "Arrestin-related trafficking adapter 3", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:14525", "name": "Reye syndrome", "description": "A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.", "url": "https://disease-ontology.org/term/DOID:14525", "evidence": [ { "id": "14525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14525" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of ubiquitin-dependent endocytosis", "id": "GO:2000397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000397", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "pmid": "" }, { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "pmid": "" }, { "name": "cellular response to L-arginine", "id": "GO:1903577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903577", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "pmid": "" }, { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47029-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 129, "start_aa": "Ser", "end_pos": 129, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser129", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47029", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47029" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 134, "start_aa": "Ser", "end_pos": 134, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser134", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47029", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47029" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 155, "start_aa": "Ser", "end_pos": 155, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser155", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47029", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47029" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Ser162", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 162, "start_aa": "Ser", "end_pos": 162, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser162", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47029", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47029" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "1011", "end_pos": "1011", "site_lbl": "Ser1011", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "1019", "end_pos": "1019", "site_lbl": "Ser1019", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "1022", "end_pos": "1022", "site_lbl": "Ser1022", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "1023", "end_pos": "1023", "site_lbl": "Ser1023", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "1036", "end_pos": "1036", "site_lbl": "Ser1036", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "1040", "end_pos": "1040", "site_lbl": "Ser1040", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "1044", "end_pos": "1044", "site_lbl": "Ser1044", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Thr153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Thr161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Ser199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Thr203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Ser213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "545", "end_pos": "545", "site_lbl": "Ser545", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "550", "end_pos": "550", "site_lbl": "Thr550", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "556", "end_pos": "556", "site_lbl": "Ser556", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "581", "end_pos": "581", "site_lbl": "Ser581", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "582", "end_pos": "582", "site_lbl": "Ser582", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Ser586", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "605", "end_pos": "605", "site_lbl": "Thr605", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "608", "end_pos": "608", "site_lbl": "Ser608", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "615", "end_pos": "615", "site_lbl": "Ser615", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "617", "end_pos": "617", "site_lbl": "Ser617", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Ser620", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "639", "end_pos": "639", "site_lbl": "Ser639", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "653", "end_pos": "653", "site_lbl": "Ser653", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "706", "end_pos": "706", "site_lbl": "Thr706", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "723", "end_pos": "723", "site_lbl": "Thr723", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "726", "end_pos": "726", "site_lbl": "Ser726", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "740", "end_pos": "740", "site_lbl": "Ser740", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "749", "end_pos": "749", "site_lbl": "Ser749", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "774", "end_pos": "774", "site_lbl": "Ser774", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "776", "end_pos": "776", "site_lbl": "Ser776", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "777", "end_pos": "777", "site_lbl": "Thr777", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "793", "end_pos": "793", "site_lbl": "Ser793", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "810", "end_pos": "810", "site_lbl": "Ser810", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "820", "end_pos": "820", "site_lbl": "Ser820", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "826", "end_pos": "826", "site_lbl": "Ser826", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "829", "end_pos": "829", "site_lbl": "Ser829", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "832", "end_pos": "832", "site_lbl": "Ser832", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "838", "end_pos": "838", "site_lbl": "Ser838", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "878", "end_pos": "878", "site_lbl": "Ser878", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "881", "end_pos": "881", "site_lbl": "Thr881", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "882", "end_pos": "882", "site_lbl": "Ser882", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "883", "end_pos": "883", "site_lbl": "Ser883", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "884", "end_pos": "884", "site_lbl": "Thr884", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "887", "end_pos": "887", "site_lbl": "Ser887", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "890", "end_pos": "890", "site_lbl": "Ser890", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "891", "end_pos": "891", "site_lbl": "Ser891", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "895", "end_pos": "895", "site_lbl": "Ser895", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "900", "end_pos": "900", "site_lbl": "Ser900", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47029", "url": "https://www.uniprot.org/uniprotkb/P47029" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "911", "end_pos": "911", "site_lbl": "Ser911", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "924", "end_pos": "924", "site_lbl": "Ser924", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "931", "end_pos": "931", "site_lbl": "Ser931", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "932", "end_pos": "932", "site_lbl": "Tyr932", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "991", "end_pos": "991", "site_lbl": "Ser991", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47029-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47029", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47029" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003620", "url": "https://www.yeastgenome.org/locus/S000003620" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47029-1" }, { "uniprot_canonical_ac": "P47030-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47030", "url": "https://www.uniprot.org/uniprotkb/P47030" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 604, "chemical_mass": 68768.0, "gene_names": "TAX4;J1002;TAX4", "protein_name": "Protein TAX4", "disease": [], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "P47030", "url": "https://www.uniprot.org/uniprotkb/P47030" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "P47030", "url": "https://www.uniprot.org/uniprotkb/P47030" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "P47030", "url": "https://www.uniprot.org/uniprotkb/P47030" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P47030", "url": "https://www.uniprot.org/uniprotkb/P47030" } ], "pmid": "" } ], "cellular_component": [ { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P47030", "url": "https://www.uniprot.org/uniprotkb/P47030" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47030-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003619", "url": "https://www.yeastgenome.org/locus/S000003619" }, { "database": "iPTMnet", "id": "P47030", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47030" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47030-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003619", "url": "https://www.yeastgenome.org/locus/S000003619" }, { "database": "iPTMnet", "id": "P47030", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47030" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P47030-1" }, { "uniprot_canonical_ac": "P47032-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 299, "chemical_mass": 30634.0, "gene_names": "PRY1;J1022;PRY1", "protein_name": "Protein PRY1", "disease": [ { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "pmid": "" }, { "name": "fatty acid binding", "id": "GO:0005504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005504", "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "pmid": "" }, { "name": "sterol binding", "id": "GO:0032934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032934", "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid transport", "id": "GO:0015908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015908", "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "pmid": "" }, { "name": "sterol transport", "id": "GO:0015918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015918", "evidence": [ { "database": "UniProtKB", "id": "P47032", "url": "https://www.uniprot.org/uniprotkb/P47032" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P47032-1" }, { "uniprot_canonical_ac": "P47033-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47033", "url": "https://www.uniprot.org/uniprotkb/P47033" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 881, "chemical_mass": 89153.0, "gene_names": "PRY3;J1027;PRY3", "protein_name": "Cell wall protein PRY3", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P47033", "url": "https://www.uniprot.org/uniprotkb/P47033" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P47033", "url": "https://www.uniprot.org/uniprotkb/P47033" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P47033", "url": "https://www.uniprot.org/uniprotkb/P47033" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P47033", "url": "https://www.uniprot.org/uniprotkb/P47033" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid transport", "id": "GO:0015908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015908", "evidence": [ { "database": "UniProtKB", "id": "P47033", "url": "https://www.uniprot.org/uniprotkb/P47033" } ], "pmid": "" }, { "name": "sterol transport", "id": "GO:0015918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015918", "evidence": [ { "database": "UniProtKB", "id": "P47033", "url": "https://www.uniprot.org/uniprotkb/P47033" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47033-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Asn101", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 101, "start_aa": "Asn", "end_pos": 101, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn101", "evidence": [ { "id": "P47033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47033#ptm_processing" }, { "id": "23038983", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23038983" } ] } ] }, { "uniprot_canonical_ac": "P47033-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Asn360", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 360, "start_aa": "Asn", "end_pos": 360, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn360", "evidence": [ { "id": "P47033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47033#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P47033-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Asn488", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 488, "start_aa": "Asn", "end_pos": 488, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn488", "evidence": [ { "id": "P47033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47033#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P47033-1", "start_pos": "535", "end_pos": "535", "site_lbl": "Asn535", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 535, "start_aa": "Asn", "end_pos": 535, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn535", "evidence": [ { "id": "P47033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47033#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P47033-1", "start_pos": "547", "end_pos": "547", "site_lbl": "Asn547", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 547, "start_aa": "Asn", "end_pos": 547, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn547", "evidence": [ { "id": "P47033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47033#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P47033-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Asn569", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 569, "start_aa": "Asn", "end_pos": 569, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn569", "evidence": [ { "id": "P47033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47033#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P47033-1", "start_pos": "625", "end_pos": "625", "site_lbl": "Asn625", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 625, "start_aa": "Asn", "end_pos": 625, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn625", "evidence": [ { "id": "P47033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P47033#ptm_processing" } ] } ] } ], "record_id": "P47033-1" }, { "uniprot_canonical_ac": "P47039-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47039", "url": "https://www.uniprot.org/uniprotkb/P47039" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 444, "chemical_mass": 50082.0, "gene_names": "BNA3;BNA3;J1138", "protein_name": "Probable kynurenine--oxoglutarate transaminase BNA3", "disease": [], "biological_process": [ { "name": "L-kynurenine catabolic process", "id": "GO:0097053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097053", "evidence": [ { "database": "UniProtKB", "id": "P47039", "url": "https://www.uniprot.org/uniprotkb/P47039" } ], "pmid": "" }, { "name": "kynurenic acid biosynthetic process", "id": "GO:0034276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034276", "evidence": [ { "database": "UniProtKB", "id": "P47039", "url": "https://www.uniprot.org/uniprotkb/P47039" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47039", "url": "https://www.uniprot.org/uniprotkb/P47039" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P47039", "url": "https://www.uniprot.org/uniprotkb/P47039" } ], "pmid": "" } ], "molecular_function": [ { "name": "kynurenine-oxoglutarate transaminase activity", "id": "GO:0016212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016212", "evidence": [ { "database": "UniProtKB", "id": "P47039", "url": "https://www.uniprot.org/uniprotkb/P47039" } ], "pmid": "" }, { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "P47039", "url": "https://www.uniprot.org/uniprotkb/P47039" } ], "pmid": "" }, { "name": "2-aminoadipate transaminase activity", "id": "GO:0047536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047536", "evidence": [ { "database": "UniProtKB", "id": "P47039", "url": "https://www.uniprot.org/uniprotkb/P47039" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47039-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003596", "url": "https://www.yeastgenome.org/locus/S000003596" }, { "database": "iPTMnet", "id": "P47039", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47039" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47039-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003596", "url": "https://www.yeastgenome.org/locus/S000003596" }, { "database": "iPTMnet", "id": "P47039", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47039" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47039-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Ser89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003596", "url": "https://www.yeastgenome.org/locus/S000003596" }, { "database": "iPTMnet", "id": "P47039", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47039" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47039-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47039", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47039" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003596", "url": "https://www.yeastgenome.org/locus/S000003596" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47039-1" }, { "uniprot_canonical_ac": "P47043-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 880, "chemical_mass": 98866.0, "gene_names": "ZAP1;J1145;ZAP1;ZRG10", "protein_name": "Zinc-responsive transcriptional regulator ZAP1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" } ], "pmid": "" }, { "name": "cellular response to zinc ion starvation", "id": "GO:0034224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034224", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47043-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 70, "start_aa": "Thr", "end_pos": 70, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr70", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Thr150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47043" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47043" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003592", "url": "https://www.yeastgenome.org/locus/S000003592" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47043" }, { "database": "SGD", "id": "S000003592", "url": "https://www.yeastgenome.org/locus/S000003592" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47043" }, { "database": "SGD", "id": "S000003592", "url": "https://www.yeastgenome.org/locus/S000003592" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Ser515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47043" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003592", "url": "https://www.yeastgenome.org/locus/S000003592" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47043" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003592", "url": "https://www.yeastgenome.org/locus/S000003592" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "856", "end_pos": "856", "site_lbl": "Ser856", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003592", "url": "https://www.yeastgenome.org/locus/S000003592" }, { "database": "iPTMnet", "id": "P47043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47043" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "858", "end_pos": "858", "site_lbl": "Ser858", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003592", "url": "https://www.yeastgenome.org/locus/S000003592" }, { "database": "iPTMnet", "id": "P47043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47043" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003592", "url": "https://www.yeastgenome.org/locus/S000003592" }, { "database": "iPTMnet", "id": "P47043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47043" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Cys202", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Results in a significant defect in zinc responsiveness; when associated with A-203 and A-207.", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" }, { "database": "PubMed", "id": "16045625", "url": "https://glygen.org/publication/PubMed/16045625" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Cys203", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Results in a significant defect in zinc responsiveness; when associated with A-202 and A-207.", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" }, { "database": "PubMed", "id": "16045625", "url": "https://glygen.org/publication/PubMed/16045625" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "In ZAP1-1up; interferes with the zinc-dependent repression of the ZRT1 promoter but does not prevent full induction of the ZRT1 gene.", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" }, { "database": "PubMed", "id": "9271382", "url": "https://glygen.org/publication/PubMed/9271382" } ] } ] }, { "uniprot_canonical_ac": "P47043-1", "start_pos": "207", "end_pos": "207", "site_lbl": "His207", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Results in a significant defect in zinc responsiveness; when associated with A-202 and A-203.", "evidence": [ { "database": "UniProtKB", "id": "P47043", "url": "https://www.uniprot.org/uniprotkb/P47043" }, { "database": "PubMed", "id": "16045625", "url": "https://glygen.org/publication/PubMed/16045625" } ] } ] } ], "record_id": "P47043-1" }, { "uniprot_canonical_ac": "P47045-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47045", "url": "https://www.uniprot.org/uniprotkb/P47045" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 478, "chemical_mass": 54183.0, "gene_names": "TIM54;J1150;TIM54", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM54", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47045", "url": "https://www.uniprot.org/uniprotkb/P47045" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P47045", "url": "https://www.uniprot.org/uniprotkb/P47045" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P47045", "url": "https://www.uniprot.org/uniprotkb/P47045" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P47045", "url": "https://www.uniprot.org/uniprotkb/P47045" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P47045", "url": "https://www.uniprot.org/uniprotkb/P47045" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P47045", "url": "https://www.uniprot.org/uniprotkb/P47045" } ], "pmid": "" }, { "name": "TIM22 mitochondrial import inner membrane insertion complex", "id": "GO:0042721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042721", "evidence": [ { "database": "UniProtKB", "id": "P47045", "url": "https://www.uniprot.org/uniprotkb/P47045" } ], "pmid": "" } ], "biological_process": [ { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "P47045", "url": "https://www.uniprot.org/uniprotkb/P47045" } ], "pmid": "" }, { "name": "protein transmembrane transport", "id": "GO:0071806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071806", "evidence": [ { "database": "UniProtKB", "id": "P47045", "url": "https://www.uniprot.org/uniprotkb/P47045" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47045-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Thr304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47045", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47045" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P47045-1" }, { "uniprot_canonical_ac": "P47050-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 842, "chemical_mass": 99326.0, "gene_names": "RTT101;CUL8;J1166;RTT101", "protein_name": "Cullin-8", "disease": [], "biological_process": [ { "name": "nonfunctional rRNA decay", "id": "GO:0070651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070651", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "transposable element silencing", "id": "GO:0010526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010526", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "Cul8-RING ubiquitin ligase complex", "id": "GO:0035361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035361", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" }, { "name": "ubiquitin ligase complex scaffold activity", "id": "GO:0160072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160072", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47050-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003583", "url": "https://www.yeastgenome.org/locus/S000003583" }, { "database": "iPTMnet", "id": "P47050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47050-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003583", "url": "https://www.yeastgenome.org/locus/S000003583" }, { "database": "iPTMnet", "id": "P47050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47050-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003583", "url": "https://www.yeastgenome.org/locus/S000003583" }, { "database": "iPTMnet", "id": "P47050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47050" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47050-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Thr752", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003583", "url": "https://www.yeastgenome.org/locus/S000003583" }, { "database": "iPTMnet", "id": "P47050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47050" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47050-1", "start_pos": "754", "end_pos": "754", "site_lbl": "Ser754", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003583", "url": "https://www.yeastgenome.org/locus/S000003583" }, { "database": "iPTMnet", "id": "P47050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47050-1", "start_pos": "791", "end_pos": "791", "site_lbl": "Lys791", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Prevents RUB1/NEDD8 modification.", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" }, { "database": "PubMed", "id": "14519104", "url": "https://glygen.org/publication/PubMed/14519104" }, { "database": "PubMed", "id": "12676951", "url": "https://glygen.org/publication/PubMed/12676951" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Prevents RUB1/NEDD8 modification.", "evidence": [ { "database": "UniProtKB", "id": "P47050", "url": "https://www.uniprot.org/uniprotkb/P47050" }, { "database": "PubMed", "id": "14519104", "url": "https://glygen.org/publication/PubMed/14519104" }, { "database": "PubMed", "id": "12676951", "url": "https://glygen.org/publication/PubMed/12676951" } ] } ] } ], "record_id": "P47050-1" }, { "uniprot_canonical_ac": "P47057-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 423, "chemical_mass": 49002.0, "gene_names": "SNX4;ATG24;CVT13;J1244;SNX4", "protein_name": "Sorting nexin-4", "disease": [], "cellular_component": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "cytoplasmic side of endosome membrane", "id": "GO:0010009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010009", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "protein localization to endosome", "id": "GO:0036010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036010", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "glycophagy", "id": "GO:0061723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061723", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" }, { "name": "early endosome to Golgi transport", "id": "GO:0034498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034498", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47057-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Thr60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47057", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47057" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P47057-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47057", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47057" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P47057-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Tyr79", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes the intracellular punctate localization and decreases the cytoplasm to vacuole transport.", "evidence": [ { "database": "UniProtKB", "id": "P47057", "url": "https://www.uniprot.org/uniprotkb/P47057" }, { "database": "PubMed", "id": "12048214", "url": "https://glygen.org/publication/PubMed/12048214" } ] } ] } ], "record_id": "P47057-1" }, { "uniprot_canonical_ac": "P47058-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47058", "url": "https://www.uniprot.org/uniprotkb/P47058" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 250, "chemical_mass": 28252.0, "gene_names": "TAD2;J1246;TAD2", "protein_name": "tRNA-specific adenosine-34 deaminase catalytic subunit TAD2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47058", "url": "https://www.uniprot.org/uniprotkb/P47058" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47058", "url": "https://www.uniprot.org/uniprotkb/P47058" } ], "pmid": "" }, { "name": "tRNA-specific adenosine-34 deaminase complex", "id": "GO:0052718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052718", "evidence": [ { "database": "UniProtKB", "id": "P47058", "url": "https://www.uniprot.org/uniprotkb/P47058" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA-specific adenosine deaminase activity", "id": "GO:0008251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008251", "evidence": [ { "database": "UniProtKB", "id": "P47058", "url": "https://www.uniprot.org/uniprotkb/P47058" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P47058", "url": "https://www.uniprot.org/uniprotkb/P47058" } ], "pmid": "" }, { "name": "tRNA-specific adenosine-34 deaminase activity", "id": "GO:0052717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052717", "evidence": [ { "database": "UniProtKB", "id": "P47058", "url": "https://www.uniprot.org/uniprotkb/P47058" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA wobble adenosine to inosine editing", "id": "GO:0002100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002100", "evidence": [ { "database": "UniProtKB", "id": "P47058", "url": "https://www.uniprot.org/uniprotkb/P47058" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "P47058", "url": "https://www.uniprot.org/uniprotkb/P47058" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P47058-1" }, { "uniprot_canonical_ac": "P47075-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 721, "chemical_mass": 83155.0, "gene_names": "VTC4;J1345;PHM3;VTC4;YJL012C-A", "protein_name": "Vacuolar transporter chaperone complex subunit 4", "disease": [], "biological_process": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "engulfment of target by autophagosome", "id": "GO:0061736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061736", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "polyphosphate metabolic process", "id": "GO:0006797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006797", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "microautophagy", "id": "GO:0016237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016237", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "polyphosphate biosynthetic process", "id": "GO:0006799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006799", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" } ], "cellular_component": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "vacuolar transporter chaperone complex", "id": "GO:0033254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033254", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" } ], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "inositol hexakisphosphate binding", "id": "GO:0000822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000822", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" }, { "name": "polyphosphate kinase activity", "id": "GO:0008976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008976", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47075-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47075" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003549", "url": "https://www.yeastgenome.org/locus/S000003549" } ] } ] }, { "uniprot_canonical_ac": "P47075-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003549", "url": "https://www.yeastgenome.org/locus/S000003549" }, { "database": "iPTMnet", "id": "P47075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47075" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P47075-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003549", "url": "https://www.yeastgenome.org/locus/S000003549" }, { "database": "iPTMnet", "id": "P47075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47075" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P47075-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Thr401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003549", "url": "https://www.yeastgenome.org/locus/S000003549" }, { "database": "iPTMnet", "id": "P47075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47075" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47075-1", "start_pos": "447", "end_pos": "447", "site_lbl": "Ser447", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003549", "url": "https://www.yeastgenome.org/locus/S000003549" }, { "database": "iPTMnet", "id": "P47075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47075" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47075-1", "start_pos": "600", "end_pos": "600", "site_lbl": "Thr600", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47075" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003549", "url": "https://www.yeastgenome.org/locus/S000003549" } ] } ] }, { "uniprot_canonical_ac": "P47075-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003549", "url": "https://www.yeastgenome.org/locus/S000003549" }, { "database": "iPTMnet", "id": "P47075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47075" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47075-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Arg264", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreases nucleotide binding by a factor of 2.5 and reduces catalytic activity. Decreases nucleotide binding by a factor of 20 and abolishes catalytic activity; when associated with A-266.", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" }, { "database": "PubMed", "id": "19390046", "url": "https://glygen.org/publication/PubMed/19390046" } ] } ] }, { "uniprot_canonical_ac": "P47075-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Arg266", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreases nucleotide binding by a factor of 4 and reduces catalytic activity. Decreases nucleotide binding by a factor of 20 and abolishes catalytic activity; when associated with A-264.", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" }, { "database": "PubMed", "id": "19390046", "url": "https://glygen.org/publication/PubMed/19390046" } ] } ] }, { "uniprot_canonical_ac": "P47075-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Glu426", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Reduces ATP turnover and polyP synthesis.", "evidence": [ { "database": "UniProtKB", "id": "P47075", "url": "https://www.uniprot.org/uniprotkb/P47075" }, { "database": "PubMed", "id": "19390046", "url": "https://glygen.org/publication/PubMed/19390046" } ] } ] } ], "record_id": "P47075-1" }, { "uniprot_canonical_ac": "P47077-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 666, "chemical_mass": 77722.0, "gene_names": "NOP9;J1357;NOP9", "protein_name": "Nucleolar protein 9", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "pmid": "" } ], "biological_process": [ { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "pmid": "" }, { "name": "ribosomal small subunit export from nucleus", "id": "GO:0000056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000056", "evidence": [ { "database": "UniProtKB", "id": "P47077", "url": "https://www.uniprot.org/uniprotkb/P47077" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47077-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Thr163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003547", "url": "https://www.yeastgenome.org/locus/S000003547" }, { "database": "iPTMnet", "id": "P47077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47077-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Ser165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003547", "url": "https://www.yeastgenome.org/locus/S000003547" }, { "database": "iPTMnet", "id": "P47077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47077-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003547", "url": "https://www.yeastgenome.org/locus/S000003547" }, { "database": "iPTMnet", "id": "P47077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47077-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Ser281", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003547", "url": "https://www.yeastgenome.org/locus/S000003547" }, { "database": "iPTMnet", "id": "P47077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47077" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47077-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003547", "url": "https://www.yeastgenome.org/locus/S000003547" }, { "database": "iPTMnet", "id": "P47077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47077-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Ser286", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003547", "url": "https://www.yeastgenome.org/locus/S000003547" }, { "database": "iPTMnet", "id": "P47077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47077-1", "start_pos": "653", "end_pos": "653", "site_lbl": "Ser653", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003547", "url": "https://www.yeastgenome.org/locus/S000003547" }, { "database": "iPTMnet", "id": "P47077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47077-1", "start_pos": "657", "end_pos": "657", "site_lbl": "Ser657", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003547", "url": "https://www.yeastgenome.org/locus/S000003547" }, { "database": "iPTMnet", "id": "P47077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47077-1" }, { "uniprot_canonical_ac": "P47082-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 602, "chemical_mass": 65346.0, "gene_names": "AVT1;AVT1;J1409;YJR83.4", "protein_name": "Vacuolar amino acid transporter 1", "disease": [ { "disease_id": "DOID:0060170", "name": "generalized epilepsy with febrile seizures plus", "description": "An idiopathic generalized epilepsy that is characterized by febrile seizures often with accessory afebrile generalized tonic-clonic seizures with childhood onset.", "url": "https://disease-ontology.org/term/DOID:0060170", "evidence": [ { "id": "0060170", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060170" } ], "weight": 0.0 }, { "disease_id": "DOID:0112202", "name": "developmental and epileptic encephalopathy", "description": "An electroclinical syndrome characterized by epileptiform activity and at least one other pathology that together contribute to cognitive and behavioral impairments including developmental delay or regression with onset anywhere from birth to adulthood.", "url": "https://disease-ontology.org/term/DOID:0112202", "evidence": [ { "id": "0112202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112202" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 } ], "biological_process": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" }, { "name": "proline transport", "id": "GO:0015824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015824", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" }, { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" }, { "name": "L-histidine transmembrane import into vacuole", "id": "GO:0090513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090513", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" } ], "molecular_function": [ { "name": "L-isoleucine transmembrane transporter activity", "id": "GO:0015188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015188", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" }, { "name": "neutral L-amino acid transmembrane transporter activity", "id": "GO:0015175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015175", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" }, { "name": "L-glutamine transmembrane transporter activity", "id": "GO:0015186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015186", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" }, { "name": "L-histidine transmembrane transporter activity", "id": "GO:0005290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005290", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" }, { "name": "L-tyrosine transmembrane transporter activity", "id": "GO:0005302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005302", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" } ], "cellular_component": [ { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47082-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Tyr100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Thr117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Thr137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Thr165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Thr169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Thr181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Thr46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47082", "url": "https://www.uniprot.org/uniprotkb/P47082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47082-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Thr99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003761", "url": "https://www.yeastgenome.org/locus/S000003761" }, { "database": "iPTMnet", "id": "P47082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47082" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47082-1" }, { "uniprot_canonical_ac": "P47093-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 109, "chemical_mass": 12385.0, "gene_names": "LSM8;J1464;LSM8;YJR83.16", "protein_name": "LSM2-LSM8 complex subunit LSM8", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "pmid": "" }, { "name": "U6 snRNP", "id": "GO:0005688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005688", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47093-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Arg57", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces affinity for poly-URNA ends.", "evidence": [ { "database": "UniProtKB", "id": "P47093", "url": "https://www.uniprot.org/uniprotkb/P47093" }, { "database": "PubMed", "id": "24240276", "url": "https://glygen.org/publication/PubMed/24240276" } ] } ] } ], "record_id": "P47093-1" }, { "uniprot_canonical_ac": "P47096-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 177, "chemical_mass": 20235.0, "gene_names": "BNA1;BNA1;HAD1;J1550", "protein_name": "3-hydroxyanthranilate 3,4-dioxygenase", "disease": [ { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" } ], "pmid": "" } ], "biological_process": [ { "name": "L-tryptophan catabolic process", "id": "GO:0006569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006569", "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" } ], "pmid": "" }, { "name": "quinolinate biosynthetic process", "id": "GO:0019805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019805", "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" } ], "pmid": "" }, { "name": "anthranilate metabolic process", "id": "GO:0043420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043420", "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" } ], "pmid": "" }, { "name": "'de novo' NAD+ biosynthetic process from L-tryptophan", "id": "GO:0034354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034354", "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" } ], "pmid": "" }, { "name": "quinolinate metabolic process", "id": "GO:0046874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046874", "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" } ], "pmid": "" } ], "molecular_function": [ { "name": "3-hydroxyanthranilate 3,4-dioxygenase activity", "id": "GO:0000334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000334", "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" } ], "pmid": "" }, { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47096-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Thr53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P47096-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Thr168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47096" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P47096-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47096", "url": "https://www.uniprot.org/uniprotkb/P47096" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47096" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003786", "url": "https://www.yeastgenome.org/locus/S000003786" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47096-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003786", "url": "https://www.yeastgenome.org/locus/S000003786" }, { "database": "iPTMnet", "id": "P47096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47096" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47096-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003786", "url": "https://www.yeastgenome.org/locus/S000003786" }, { "database": "iPTMnet", "id": "P47096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47096" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47096-1" }, { "uniprot_canonical_ac": "P47098-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1755, "chemical_mass": 198652.0, "gene_names": "TY1B-JR1;J1560;YJRWTy1-1 POL", "protein_name": "Transposon Ty1-JR1 Gag-Pol polyprotein", "disease": [], "molecular_function": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "transposition", "id": "GO:0032196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032196", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" }, { "name": "viral translational frameshifting", "id": "GO:0075523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075523", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47098-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 143, "start_aa": "Thr", "end_pos": 143, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr143", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P47098-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Thr281", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 281, "start_aa": "Thr", "end_pos": 281, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr281", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P47098-1", "start_pos": "962", "end_pos": "962", "site_lbl": "Thr962", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 962, "start_aa": "Thr", "end_pos": 962, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr962", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P47098-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Ser416", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47098", "url": "https://www.uniprot.org/uniprotkb/P47098" } ] } ] }, { "uniprot_canonical_ac": "P47098-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47098", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47098" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P47098-1", "start_pos": "936", "end_pos": "936", "site_lbl": "Ser936", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47098", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47098" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ] }, { "uniprot_canonical_ac": "P47098-1", "start_pos": "942", "end_pos": "942", "site_lbl": "Ser942", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47098", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47098" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ] } ], "record_id": "P47098-1" }, { "uniprot_canonical_ac": "P47100-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1755, "chemical_mass": 198618.0, "gene_names": "TY1B-JR2;J1570;YJRWTy1-2 POL", "protein_name": "Transposon Ty1-JR2 Gag-Pol polyprotein", "disease": [], "molecular_function": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "transposition", "id": "GO:0032196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032196", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" }, { "name": "viral translational frameshifting", "id": "GO:0075523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075523", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47100-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 143, "start_aa": "Thr", "end_pos": 143, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr143", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Thr281", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 281, "start_aa": "Thr", "end_pos": 281, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr281", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 36, "start_aa": "Ser", "end_pos": 36, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser36", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47100", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47100" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 38, "start_aa": "Ser", "end_pos": 38, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser38", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47100", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47100" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 404, "start_aa": "Ser", "end_pos": 404, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser404", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47100", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47100" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Ser406", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 406, "start_aa": "Ser", "end_pos": 406, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser406", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47100", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47100" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "409", "end_pos": "409", "site_lbl": "Ser409", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 409, "start_aa": "Ser", "end_pos": 409, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser409", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47100", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47100" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "411", "end_pos": "411", "site_lbl": "Ser411", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 411, "start_aa": "Ser", "end_pos": 411, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser411", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47100", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47100" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Ser416", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 416, "start_aa": "Ser", "end_pos": 416, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser416", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47100", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47100" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47100", "url": "https://www.uniprot.org/uniprotkb/P47100" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "418", "end_pos": "418", "site_lbl": "Ser418", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 418, "start_aa": "Ser", "end_pos": 418, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser418", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47100", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47100" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "962", "end_pos": "962", "site_lbl": "Thr962", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 962, "start_aa": "Thr", "end_pos": 962, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr962", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "1004", "end_pos": "1004", "site_lbl": "Ser1004", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47100", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47100" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "1005", "end_pos": "1005", "site_lbl": "Ser1005", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47100", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47100" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "1006", "end_pos": "1006", "site_lbl": "Thr1006", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47100", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47100" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "1010", "end_pos": "1010", "site_lbl": "Ser1010", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47100", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47100" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P47100-1", "start_pos": "1014", "end_pos": "1014", "site_lbl": "Ser1014", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47100", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47100" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] } ], "record_id": "P47100-1" }, { "uniprot_canonical_ac": "P47112-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47112", "url": "https://www.uniprot.org/uniprotkb/P47112" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 604, "chemical_mass": 68405.0, "gene_names": "TAH11;CDT1;J1641;SID2;TAH11", "protein_name": "Cell division cycle protein CDT1", "disease": [], "molecular_function": [ { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "P47112", "url": "https://www.uniprot.org/uniprotkb/P47112" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pre-replicative complex", "id": "GO:0005656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005656", "evidence": [ { "database": "UniProtKB", "id": "P47112", "url": "https://www.uniprot.org/uniprotkb/P47112" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47112", "url": "https://www.uniprot.org/uniprotkb/P47112" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P47112", "url": "https://www.uniprot.org/uniprotkb/P47112" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47112", "url": "https://www.uniprot.org/uniprotkb/P47112" } ], "pmid": "" } ], "biological_process": [ { "name": "pre-replicative complex assembly involved in nuclear cell cycle DNA replication", "id": "GO:0006267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006267", "evidence": [ { "database": "UniProtKB", "id": "P47112", "url": "https://www.uniprot.org/uniprotkb/P47112" } ], "pmid": "" }, { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "P47112", "url": "https://www.uniprot.org/uniprotkb/P47112" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P47112", "url": "https://www.uniprot.org/uniprotkb/P47112" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "P47112", "url": "https://www.uniprot.org/uniprotkb/P47112" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47112-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Thr382", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47112", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47112" } ] } ] }, { "uniprot_canonical_ac": "P47112-1", "start_pos": "437", "end_pos": "437", "site_lbl": "Ser437", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47112" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P47112-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Thr441", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47112" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P47112-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Ser466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47112" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003807", "url": "https://www.yeastgenome.org/locus/S000003807" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47112-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Ser479", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47112" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003807", "url": "https://www.yeastgenome.org/locus/S000003807" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P47112-1" }, { "uniprot_canonical_ac": "P47114-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47114", "url": "https://www.uniprot.org/uniprotkb/P47114" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 497, "chemical_mass": 57517.0, "gene_names": "KCH1;J1669;KCH1", "protein_name": "Low affinity K(+) transporter 1", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P47114", "url": "https://www.uniprot.org/uniprotkb/P47114" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P47114", "url": "https://www.uniprot.org/uniprotkb/P47114" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P47114", "url": "https://www.uniprot.org/uniprotkb/P47114" } ], "pmid": "" }, { "name": "mating projection", "id": "GO:0005937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005937", "evidence": [ { "database": "UniProtKB", "id": "P47114", "url": "https://www.uniprot.org/uniprotkb/P47114" } ], "pmid": "" } ], "molecular_function": [ { "name": "potassium ion transmembrane transporter activity", "id": "GO:0015079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015079", "evidence": [ { "database": "UniProtKB", "id": "P47114", "url": "https://www.uniprot.org/uniprotkb/P47114" } ], "pmid": "" } ], "biological_process": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "P47114", "url": "https://www.uniprot.org/uniprotkb/P47114" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47114-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Ser291", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47114", "url": "https://www.uniprot.org/uniprotkb/P47114" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47114", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47114" }, { "database": "SGD", "id": "S000003815", "url": "https://www.yeastgenome.org/locus/S000003815" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47114-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Thr293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47114", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47114" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003815", "url": "https://www.yeastgenome.org/locus/S000003815" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47114-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47114", "url": "https://www.uniprot.org/uniprotkb/P47114" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47114", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47114" }, { "database": "SGD", "id": "S000003815", "url": "https://www.yeastgenome.org/locus/S000003815" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47114-1", "start_pos": "345", "end_pos": "345", "site_lbl": "Thr345", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003815", "url": "https://www.yeastgenome.org/locus/S000003815" }, { "database": "iPTMnet", "id": "P47114", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47114" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47114-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Thr347", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003815", "url": "https://www.yeastgenome.org/locus/S000003815" }, { "database": "iPTMnet", "id": "P47114", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47114" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47114-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Ser350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003815", "url": "https://www.yeastgenome.org/locus/S000003815" }, { "database": "iPTMnet", "id": "P47114", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47114" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47114-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003815", "url": "https://www.yeastgenome.org/locus/S000003815" }, { "database": "iPTMnet", "id": "P47114", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47114" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47114-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Ser400", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003815", "url": "https://www.yeastgenome.org/locus/S000003815" }, { "database": "iPTMnet", "id": "P47114", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47114" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47114-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Ser401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003815", "url": "https://www.yeastgenome.org/locus/S000003815" }, { "database": "iPTMnet", "id": "P47114", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47114" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47114-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Thr417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003815", "url": "https://www.yeastgenome.org/locus/S000003815" }, { "database": "iPTMnet", "id": "P47114", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47114" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47114-1" }, { "uniprot_canonical_ac": "P47116-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 818, "chemical_mass": 91400.0, "gene_names": "PTK2;J1725;PTK2;STK2", "protein_name": "Serine/threonine-protein kinase PTK2/STK2", "disease": [], "biological_process": [ { "name": "spermine transport", "id": "GO:0000296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000296", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "intracellular monoatomic ion homeostasis", "id": "GO:0006873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006873", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "putrescine transport", "id": "GO:0015847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015847", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "regulation of cell size", "id": "GO:0008361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008361", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "spermidine transport", "id": "GO:0015848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015848", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47116-1", "start_pos": "773", "end_pos": "773", "site_lbl": "Ser773", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 773, "start_aa": "Ser", "end_pos": 773, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser773", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "774", "end_pos": "774", "site_lbl": "Ser774", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 774, "start_aa": "Ser", "end_pos": 774, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser774", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "775", "end_pos": "775", "site_lbl": "Ser775", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 775, "start_aa": "Ser", "end_pos": 775, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser775", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "776", "end_pos": "776", "site_lbl": "Ser776", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 776, "start_aa": "Ser", "end_pos": 776, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser776", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "778", "end_pos": "778", "site_lbl": "Ser778", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 778, "start_aa": "Ser", "end_pos": 778, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser778", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "781", "end_pos": "781", "site_lbl": "Ser781", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 781, "start_aa": "Ser", "end_pos": 781, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser781", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "784", "end_pos": "784", "site_lbl": "Ser784", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 784, "start_aa": "Ser", "end_pos": 784, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser784", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "786", "end_pos": "786", "site_lbl": "Ser786", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 786, "start_aa": "Ser", "end_pos": 786, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser786", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "788", "end_pos": "788", "site_lbl": "Ser788", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 788, "start_aa": "Ser", "end_pos": 788, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser788", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "789", "end_pos": "789", "site_lbl": "Ser789", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 789, "start_aa": "Ser", "end_pos": 789, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser789", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "790", "end_pos": "790", "site_lbl": "Ser790", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 790, "start_aa": "Ser", "end_pos": 790, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser790", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47116", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47116" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Thr136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Thr160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Ser190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Thr198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Ser294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Ser585", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Thr586", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "587", "end_pos": "587", "site_lbl": "Ser587", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "588", "end_pos": "588", "site_lbl": "Thr588", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "592", "end_pos": "592", "site_lbl": "Ser592", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "595", "end_pos": "595", "site_lbl": "Ser595", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "623", "end_pos": "623", "site_lbl": "Ser623", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "630", "end_pos": "630", "site_lbl": "Ser630", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Ser632", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Thr647", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "694", "end_pos": "694", "site_lbl": "Ser694", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "700", "end_pos": "700", "site_lbl": "Thr700", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "702", "end_pos": "702", "site_lbl": "Thr702", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "711", "end_pos": "711", "site_lbl": "Ser711", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Ser715", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "722", "end_pos": "722", "site_lbl": "Ser722", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "726", "end_pos": "726", "site_lbl": "Ser726", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "727", "end_pos": "727", "site_lbl": "Thr727", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "729", "end_pos": "729", "site_lbl": "Thr729", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "730", "end_pos": "730", "site_lbl": "Thr730", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "732", "end_pos": "732", "site_lbl": "Thr732", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "737", "end_pos": "737", "site_lbl": "Thr737", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Ser752", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "755", "end_pos": "755", "site_lbl": "Ser755", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "758", "end_pos": "758", "site_lbl": "Ser758", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "760", "end_pos": "760", "site_lbl": "Thr760", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "763", "end_pos": "763", "site_lbl": "Ser763", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "768", "end_pos": "768", "site_lbl": "Ser768", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47116", "url": "https://www.uniprot.org/uniprotkb/P47116" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "817", "end_pos": "817", "site_lbl": "Ser817", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P47116-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003820", "url": "https://www.yeastgenome.org/locus/S000003820" }, { "database": "iPTMnet", "id": "P47116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47116" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] } ], "record_id": "P47116-1" }, { "uniprot_canonical_ac": "P47117-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 449, "chemical_mass": 49542.0, "gene_names": "ARP3;ACT4;ARP3;J1760", "protein_name": "Actin-related protein 3", "disease": [ { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1312", "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ], "weight": 0.0 }, { "disease_id": "DOID:13768", "name": "opisthorchiasis", "description": "A parasitic helminthiasis infectious disease that involves parasitic infection of the liver, pancreas and gall bladder by Opisthorchis viverrini or Opisthorchis felineus. The symptoms include dyspepsia, abdominal pain, diarrhea, constipation, hepatomegaly, cholangitis, cholecystitis, and cholangiocarcinoma.", "url": "https://disease-ontology.org/term/DOID:13768", "evidence": [ { "id": "13768", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13768" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:4948", "name": "gallbladder carcinoma", "description": "A gallbladder cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4948", "evidence": [ { "id": "4948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4948" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "pmid": "" }, { "name": "Arp2/3 protein complex", "id": "GO:0005885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005885", "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "pmid": "" } ], "biological_process": [ { "name": "Arp2/3 complex-mediated actin nucleation", "id": "GO:0034314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314", "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "pmid": "" }, { "name": "actin nucleation", "id": "GO:0045010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045010", "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "pmid": "" }, { "name": "actin cortical patch organization", "id": "GO:0044396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044396", "evidence": [ { "database": "UniProtKB", "id": "P47117", "url": "https://www.uniprot.org/uniprotkb/P47117" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47117-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Ser111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003826", "url": "https://www.yeastgenome.org/locus/S000003826" }, { "database": "iPTMnet", "id": "P47117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47117" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47117-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003826", "url": "https://www.yeastgenome.org/locus/S000003826" }, { "database": "iPTMnet", "id": "P47117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47117" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47117-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003826", "url": "https://www.yeastgenome.org/locus/S000003826" }, { "database": "iPTMnet", "id": "P47117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47117" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47117-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47117" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P47117-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003826", "url": "https://www.yeastgenome.org/locus/S000003826" }, { "database": "iPTMnet", "id": "P47117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47117" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47117-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Ser375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003826", "url": "https://www.yeastgenome.org/locus/S000003826" }, { "database": "iPTMnet", "id": "P47117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47117" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47117-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47117" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003826", "url": "https://www.yeastgenome.org/locus/S000003826" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47117-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Thr390", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003826", "url": "https://www.yeastgenome.org/locus/S000003826" }, { "database": "iPTMnet", "id": "P47117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47117" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47117-1", "start_pos": "444", "end_pos": "444", "site_lbl": "Ser444", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003826", "url": "https://www.yeastgenome.org/locus/S000003826" }, { "database": "iPTMnet", "id": "P47117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47117" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47117-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003826", "url": "https://www.yeastgenome.org/locus/S000003826" }, { "database": "iPTMnet", "id": "P47117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47117" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47117-1" }, { "uniprot_canonical_ac": "P47119-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 197, "chemical_mass": 22093.0, "gene_names": "HAM1;HAM1;J1811", "protein_name": "Inosine triphosphate pyrophosphatase", "disease": [ { "disease_id": "DOID:0080458", "name": "developmental and epileptic encephalopathy 35", "description": "A developmental and epileptic encephalopathy characterized by seizure onset in the first months of life, absence of normal development and absence of myelination of early neurological structures that has_material_basis_in homozygous or compound heterozygous mutation in the ITPA gene on chromosome 20p13.", "url": "https://disease-ontology.org/term/DOID:0080458", "evidence": [ { "id": "0080458", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080458" } ], "weight": 0.0 }, { "disease_id": "DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood.", "url": "https://disease-ontology.org/term/DOID:1588", "evidence": [ { "id": "1588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ], "weight": 0.0 }, { "disease_id": "DOID:1883", "name": "hepatitis C", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in hepatitis C virus (Hepacivirus hominis), which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.", "url": "https://disease-ontology.org/term/DOID:1883", "evidence": [ { "id": "1883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1883" } ], "weight": 0.0 }, { "disease_id": "DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.", "url": "https://disease-ontology.org/term/DOID:2355", "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ], "weight": 0.0 }, { "disease_id": "DOID:583", "name": "hemolytic anemia", "description": "A normocytic anemia that is characterized by the rate of descruction of red blood cells exceeding the rate than they can be made.", "url": "https://disease-ontology.org/term/DOID:583", "evidence": [ { "id": "583", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:583" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "dCTP diphosphatase activity", "id": "GO:0047840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047840", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "GTP diphosphatase activity", "id": "GO:0036219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036219", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "nucleoside triphosphate diphosphatase activity", "id": "GO:0047429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047429", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "dUTP diphosphatase activity", "id": "GO:0004170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004170", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "dATP diphosphatase activity", "id": "GO:0008828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008828", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "dITP diphosphatase activity", "id": "GO:0035870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035870", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "ITP diphosphatase activity", "id": "GO:0036220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036220", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "XTP diphosphatase activity", "id": "GO:0036222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036222", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "UTP diphosphatase activity", "id": "GO:0036221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036221", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "dTTP diphosphatase activity", "id": "GO:0036218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036218", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "dGTP diphosphatase activity", "id": "GO:0036217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036217", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "nucleoside triphosphate catabolic process", "id": "GO:0009143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009143", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "purine deoxyribonucleoside triphosphate catabolic process", "id": "GO:0009217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009217", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" }, { "name": "pyrimidine deoxyribonucleoside triphosphate catabolic process", "id": "GO:0009213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009213", "evidence": [ { "database": "UniProtKB", "id": "P47119", "url": "https://www.uniprot.org/uniprotkb/P47119" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47119-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003830", "url": "https://www.yeastgenome.org/locus/S000003830" }, { "database": "iPTMnet", "id": "P47119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47119" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47119-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47119" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P47119-1" }, { "uniprot_canonical_ac": "P47122-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 385, "chemical_mass": 43195.0, "gene_names": "NPA3;EPA1;GPN1;J1821;NPA3", "protein_name": "GPN-loop GTPase 1", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47122-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Ser304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Ser308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Thr32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Thr337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Thr344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Tyr35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Thr370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "373", "end_pos": "373", "site_lbl": "Ser373", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003833", "url": "https://www.yeastgenome.org/locus/S000003833" }, { "database": "iPTMnet", "id": "P47122", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47122" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Asp106", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Impairs nuclear localization of RNAPII. Completely abolishes RNAPII binding. Loss of GTP hydrolysis activity.", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" }, { "database": "PubMed", "id": "21844196", "url": "https://glygen.org/publication/PubMed/21844196" }, { "database": "PubMed", "id": "26711263", "url": "https://glygen.org/publication/PubMed/26711263" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Gln110", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "L", "comment": "Impairs nuclear localization of RNAPII, but does not impair RNAPII binding. Loss of GTP hydrolysis activity.", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" }, { "database": "PubMed", "id": "21844196", "url": "https://glygen.org/publication/PubMed/21844196" }, { "database": "PubMed", "id": "26711263", "url": "https://glygen.org/publication/PubMed/26711263" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Glu112", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Impairs heterodimer formation with GPN2 and GPN3.", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" }, { "database": "PubMed", "id": "23324351", "url": "https://glygen.org/publication/PubMed/23324351" } ] } ] }, { "uniprot_canonical_ac": "P47122-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Asp40", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of GTP hydrolysis activity.", "evidence": [ { "database": "UniProtKB", "id": "P47122", "url": "https://www.uniprot.org/uniprotkb/P47122" }, { "database": "PubMed", "id": "26711263", "url": "https://glygen.org/publication/PubMed/26711263" } ] } ] } ], "record_id": "P47122-1" }, { "uniprot_canonical_ac": "P47128-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47128", "url": "https://www.uniprot.org/uniprotkb/P47128" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 113, "chemical_mass": 12895.0, "gene_names": "EAF6;EAF6;J1854", "protein_name": "Chromatin modification-related protein EAF6", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47128", "url": "https://www.uniprot.org/uniprotkb/P47128" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "P47128", "url": "https://www.uniprot.org/uniprotkb/P47128" } ], "pmid": "" }, { "name": "NuA3a histone acetyltransferase complex", "id": "GO:1990467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990467", "evidence": [ { "database": "UniProtKB", "id": "P47128", "url": "https://www.uniprot.org/uniprotkb/P47128" } ], "pmid": "" }, { "name": "NuA3b histone acetyltransferase complex", "id": "GO:1990468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990468", "evidence": [ { "database": "UniProtKB", "id": "P47128", "url": "https://www.uniprot.org/uniprotkb/P47128" } ], "pmid": "" }, { "name": "NuA3 histone acetyltransferase complex", "id": "GO:0033100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033100", "evidence": [ { "database": "UniProtKB", "id": "P47128", "url": "https://www.uniprot.org/uniprotkb/P47128" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P47128", "url": "https://www.uniprot.org/uniprotkb/P47128" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P47128", "url": "https://www.uniprot.org/uniprotkb/P47128" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P47128", "url": "https://www.uniprot.org/uniprotkb/P47128" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47128-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003842", "url": "https://www.yeastgenome.org/locus/S000003842" }, { "database": "iPTMnet", "id": "P47128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47128" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47128-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003842", "url": "https://www.yeastgenome.org/locus/S000003842" }, { "database": "iPTMnet", "id": "P47128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47128" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47128-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003842", "url": "https://www.yeastgenome.org/locus/S000003842" }, { "database": "iPTMnet", "id": "P47128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47128" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47128-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003842", "url": "https://www.yeastgenome.org/locus/S000003842" }, { "database": "iPTMnet", "id": "P47128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47128" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47128-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003842", "url": "https://www.yeastgenome.org/locus/S000003842" }, { "database": "iPTMnet", "id": "P47128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47128" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P47128-1" }, { "uniprot_canonical_ac": "P47134-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 954, "chemical_mass": 108667.0, "gene_names": "BIR1;BIR1;J1880", "protein_name": "Chromosomal passenger complex protein BIR1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "chromosome passenger complex", "id": "GO:0032133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032133", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle spindle assembly checkpoint", "id": "GO:0090267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090267", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "sister chromatid biorientation", "id": "GO:0031134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031134", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "mitotic spindle elongation", "id": "GO:0000022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000022", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" }, { "name": "attachment of meiotic spindle microtubules to kinetochore", "id": "GO:0051316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051316", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47134-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Ser255", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Thr257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Ser263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Ser290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Thr306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Ser316", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Ser330", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Thr344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "345", "end_pos": "345", "site_lbl": "Thr345", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Ser364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Thr365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Thr367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Thr379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Ser381", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Ser382", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Ser383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "16381814", "url": "https://glygen.org/publication/PubMed/16381814" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Ser395", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "16381814", "url": "https://glygen.org/publication/PubMed/16381814" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Ser405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Ser408", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Ser477", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Thr488", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "21725298", "url": "https://glygen.org/publication/PubMed/21725298" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Thr492", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "505", "end_pos": "505", "site_lbl": "Ser505", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "508", "end_pos": "508", "site_lbl": "Ser508", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "524", "end_pos": "524", "site_lbl": "Ser524", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "525", "end_pos": "525", "site_lbl": "Ser525", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Thr526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "552", "end_pos": "552", "site_lbl": "Ser552", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "16381814", "url": "https://glygen.org/publication/PubMed/16381814" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "582", "end_pos": "582", "site_lbl": "Ser582", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "583", "end_pos": "583", "site_lbl": "Thr583", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "587", "end_pos": "587", "site_lbl": "Ser587", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "16381814", "url": "https://glygen.org/publication/PubMed/16381814" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Ser596", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "600", "end_pos": "600", "site_lbl": "Ser600", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Ser601", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Thr604", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "616", "end_pos": "616", "site_lbl": "Ser616", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "618", "end_pos": "618", "site_lbl": "Thr618", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "619", "end_pos": "619", "site_lbl": "Ser619", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Ser620", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Ser640", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "667", "end_pos": "667", "site_lbl": "Ser667", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "16381814", "url": "https://glygen.org/publication/PubMed/16381814" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Thr684", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "16381814", "url": "https://glygen.org/publication/PubMed/16381814" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "688", "end_pos": "688", "site_lbl": "Ser688", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "16381814", "url": "https://glygen.org/publication/PubMed/16381814" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "694", "end_pos": "694", "site_lbl": "Thr694", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "696", "end_pos": "696", "site_lbl": "Ser696", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "704", "end_pos": "704", "site_lbl": "Ser704", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "722", "end_pos": "722", "site_lbl": "Thr722", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "730", "end_pos": "730", "site_lbl": "Ser730", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "735", "end_pos": "735", "site_lbl": "Thr735", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "16381814", "url": "https://glygen.org/publication/PubMed/16381814" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "745", "end_pos": "745", "site_lbl": "Thr745", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "747", "end_pos": "747", "site_lbl": "Thr747", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "16381814", "url": "https://glygen.org/publication/PubMed/16381814" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "751", "end_pos": "751", "site_lbl": "Ser751", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "765", "end_pos": "765", "site_lbl": "Ser765", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47134", "url": "https://www.uniprot.org/uniprotkb/P47134" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "775", "end_pos": "775", "site_lbl": "Ser775", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "776", "end_pos": "776", "site_lbl": "Ser776", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "777", "end_pos": "777", "site_lbl": "Thr777", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "800", "end_pos": "800", "site_lbl": "Ser800", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "803", "end_pos": "803", "site_lbl": "Ser803", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "804", "end_pos": "804", "site_lbl": "Ser804", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "809", "end_pos": "809", "site_lbl": "Ser809", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "818", "end_pos": "818", "site_lbl": "Thr818", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "819", "end_pos": "819", "site_lbl": "Ser819", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "820", "end_pos": "820", "site_lbl": "Thr820", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "821", "end_pos": "821", "site_lbl": "Ser821", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "830", "end_pos": "830", "site_lbl": "Ser830", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47134-1", "start_pos": "831", "end_pos": "831", "site_lbl": "Ser831", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003849", "url": "https://www.yeastgenome.org/locus/S000003849" }, { "database": "iPTMnet", "id": "P47134", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47134" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47134-1" }, { "uniprot_canonical_ac": "P47142-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47142", "url": "https://www.uniprot.org/uniprotkb/P47142" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 202, "chemical_mass": 23558.0, "gene_names": "VPS25;J1957;VPL12;VPS25;VPT25", "protein_name": "Vacuolar protein-sorting-associated protein 25", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ESCRT II complex", "id": "GO:0000814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000814", "evidence": [ { "database": "UniProtKB", "id": "P47142", "url": "https://www.uniprot.org/uniprotkb/P47142" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P47142", "url": "https://www.uniprot.org/uniprotkb/P47142" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043328", "evidence": [ { "database": "UniProtKB", "id": "P47142", "url": "https://www.uniprot.org/uniprotkb/P47142" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P47142", "url": "https://www.uniprot.org/uniprotkb/P47142" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P47142", "url": "https://www.uniprot.org/uniprotkb/P47142" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "P47142", "url": "https://www.uniprot.org/uniprotkb/P47142" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "P47142", "url": "https://www.uniprot.org/uniprotkb/P47142" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "P47142", "url": "https://www.uniprot.org/uniprotkb/P47142" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "P47142", "url": "https://www.uniprot.org/uniprotkb/P47142" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P47142-1" }, { "uniprot_canonical_ac": "P47143-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47143", "url": "https://www.uniprot.org/uniprotkb/P47143" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 340, "chemical_mass": 36372.0, "gene_names": "ADO1;ADO1;J1973", "protein_name": "Adenosine kinase", "disease": [ { "disease_id": "DOID:0111038", "name": "hypermethioninemia due to adenosine kinase deficiency", "description": "A hypermethioninemia characterized by autosomal recessive inheritance of developmental delay, early-onset seizures, mild dysmorphic features, and characteristic biochemical anomalies, including persistent hypermethioninemia that has_material_basis_in homozygous mutation in the ADK gene on chromosome 10q22.", "url": "https://disease-ontology.org/term/DOID:0111038", "evidence": [ { "id": "0111038", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111038" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 }, { "disease_id": "DOID:3454", "name": "brain infarction", "description": "A cerebrovascular disease that is characterized by tissue necrosis located_in the brain, resulting from inadequate blood flow through the brain.", "url": "https://disease-ontology.org/term/DOID:3454", "evidence": [ { "id": "3454", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3454" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P47143", "url": "https://www.uniprot.org/uniprotkb/P47143" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P47143", "url": "https://www.uniprot.org/uniprotkb/P47143" } ], "pmid": "" }, { "name": "adenosine kinase activity", "id": "GO:0004001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004001", "evidence": [ { "database": "UniProtKB", "id": "P47143", "url": "https://www.uniprot.org/uniprotkb/P47143" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47143", "url": "https://www.uniprot.org/uniprotkb/P47143" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47143", "url": "https://www.uniprot.org/uniprotkb/P47143" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P47143", "url": "https://www.uniprot.org/uniprotkb/P47143" } ], "pmid": "" } ], "biological_process": [ { "name": "AMP salvage", "id": "GO:0044209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044209", "evidence": [ { "database": "UniProtKB", "id": "P47143", "url": "https://www.uniprot.org/uniprotkb/P47143" } ], "pmid": "" }, { "name": "purine ribonucleoside salvage", "id": "GO:0006166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006166", "evidence": [ { "database": "UniProtKB", "id": "P47143", "url": "https://www.uniprot.org/uniprotkb/P47143" } ], "pmid": "" }, { "name": "purine nucleobase metabolic process", "id": "GO:0006144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006144", "evidence": [ { "database": "UniProtKB", "id": "P47143", "url": "https://www.uniprot.org/uniprotkb/P47143" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47143-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003866", "url": "https://www.yeastgenome.org/locus/S000003866" }, { "database": "iPTMnet", "id": "P47143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47143" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47143-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Tyr110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003866", "url": "https://www.yeastgenome.org/locus/S000003866" }, { "database": "iPTMnet", "id": "P47143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47143" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47143-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Thr126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003866", "url": "https://www.yeastgenome.org/locus/S000003866" }, { "database": "iPTMnet", "id": "P47143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47143" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47143-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Ser131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003866", "url": "https://www.yeastgenome.org/locus/S000003866" }, { "database": "iPTMnet", "id": "P47143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47143" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47143-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Ser249", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003866", "url": "https://www.yeastgenome.org/locus/S000003866" }, { "database": "iPTMnet", "id": "P47143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47143" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47143-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ser273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003866", "url": "https://www.yeastgenome.org/locus/S000003866" }, { "database": "iPTMnet", "id": "P47143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47143" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47143-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003866", "url": "https://www.yeastgenome.org/locus/S000003866" }, { "database": "iPTMnet", "id": "P47143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47143" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47143-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Ser337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003866", "url": "https://www.yeastgenome.org/locus/S000003866" }, { "database": "iPTMnet", "id": "P47143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47143" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47143-1" }, { "uniprot_canonical_ac": "P47154-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 453, "chemical_mass": 52324.0, "gene_names": "STE24;AFC1;J2032;PIO2;STE24", "protein_name": "CAAX prenyl protease 1", "disease": [ { "disease_id": "DOID:0050440", "name": "familial partial lipodystrophy", "description": "A partial lipodystrophy characterized by abnormal subcutaneous adipose tissue distribution beginning in late childhood or early adult life.", "url": "https://disease-ontology.org/term/DOID:0050440", "evidence": [ { "id": "0050440", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050440" } ], "weight": 0.0 }, { "disease_id": "DOID:0060762", "name": "restrictive dermopathy", "description": "A skin disease characterized by thin, tightly adherent translucent skin with erosions at flexure sites, superficial vessels, typical facial dysmorphism, and generalized joint ankylosis. Prenatal signs may include intrauterine growth retardation, reduced fetal movements, polyhydramnios, and premature rupture of the membranes. Most infants die within the first week of life.", "url": "https://disease-ontology.org/term/DOID:0060762", "evidence": [ { "id": "0060762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060762" } ], "weight": 0.0 }, { "disease_id": "DOID:0070369", "name": "restrictive dermopathy 1", "description": "A restrictive dermopathy that has_material_basis_in homozygous or compound heterozygous mutation in the ZMPSTE24 gene on chromosome 1p34.", "url": "https://disease-ontology.org/term/DOID:0070369", "evidence": [ { "id": "0070369", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070369" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0081129", "name": "mandibuloacral dysplasia type B lipodystrophy", "description": "A mandibuloacral dysplasia that has_material_basis_in compound heterozygous mutation in the ZMPSTE24 gene on chromosome 1p34 and that is characterized by postnatal growth retardation, craniofacial anomalies such as mandibular hypoplasia, skeletal anomalies such as progressive osteolysis of the terminal phalanges and clavicles, and skin changes such as mottled hyperpigmentation and atrophy. The lipodystrophy is characterized by generalized loss of subcutaneous fat involving the face, trunk, and extremities.", "url": "https://disease-ontology.org/term/DOID:0081129", "evidence": [ { "id": "0081129", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081129" } ], "weight": 0.0 }, { "disease_id": "DOID:11726", "name": "Emery-Dreifuss muscular dystrophy", "description": "A muscular dystrophy that chiefly affects muscles used for movement (skeletal) and heart (cardiac) muscle.", "url": "https://disease-ontology.org/term/DOID:11726", "evidence": [ { "id": "11726", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11726" } ], "weight": 0.0 }, { "disease_id": "DOID:3911", "name": "progeria", "description": "A progeroid syndrome characterized by extreme short stature, low body weight, early loss of hair, lipodystrophy, scleroderma, decreased joint mobility, osteolysis, and facial features that resemble aged persons that has_material_basis_in mutation in the LMNA gene on chromosome 1q22.", "url": "https://disease-ontology.org/term/DOID:3911", "evidence": [ { "id": "3911", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3911" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "CAAX-box protein processing", "id": "GO:0071586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071586", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" }, { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" }, { "name": "post-translational protein targeting to membrane, translocation", "id": "GO:0031204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031204", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" }, { "name": "negative regulation of post-translational protein targeting to membrane, translocation", "id": "GO:0120236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120236", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" }, { "name": "peptide pheromone maturation", "id": "GO:0007323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007323", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" } ], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "P47154", "url": "https://www.uniprot.org/uniprotkb/P47154" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47154-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Ser419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003878", "url": "https://www.yeastgenome.org/locus/S000003878" }, { "database": "iPTMnet", "id": "P47154", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47154" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47154-1" }, { "uniprot_canonical_ac": "P47156-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 728, "chemical_mass": 84984.0, "gene_names": "JHD2;J2035;JHD2;KDM5", "protein_name": "Histone demethylase JHD2", "disease": [ { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060809", "name": "syndromic X-linked intellectual disability Claes-Jensen type", "description": "A syndromic X-linked intellectual disability characterized by severe intellectual deficit associated with variable clinical manifestations including spasticity, cryptorchidism, maxillary hypoplasia, alopecia areata, epilepsy, short stature, impaired speech and behavioral problems that has_material_basis_in mutation in the KDM5C gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0060809", "evidence": [ { "id": "0060809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060809" } ], "weight": 0.0 }, { "disease_id": "DOID:0081226", "name": "autosomal recessive intellectual developmental disorder 65", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous or compound heterozygous mutation in the KDM5B gene on chromosome 1q32.", "url": "https://disease-ontology.org/term/DOID:0081226", "evidence": [ { "id": "0081226", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081226" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:11383", "name": "cryptorchidism", "description": "", "url": "https://disease-ontology.org/term/DOID:11383", "evidence": [ { "id": "11383", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11383" } ], "weight": 0.0 }, { "disease_id": "DOID:12190", "name": "descending colon cancer", "description": "", "url": "https://disease-ontology.org/term/DOID:12190", "evidence": [ { "id": "12190", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12190" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:5517", "name": "stomach carcinoma", "description": "A stomach cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:5517", "evidence": [ { "id": "5517", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5517" } ], "weight": 0.0 }, { "disease_id": "DOID:6039", "name": "uveal melanoma", "description": "A uveal cancer that has_material_basis_in uvea pigment cells.", "url": "https://disease-ontology.org/term/DOID:6039", "evidence": [ { "id": "6039", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6039" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.", "url": "https://disease-ontology.org/term/DOID:7147", "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:986", "name": "alopecia areata", "description": "An autoimmune disease resulting in the loss of hair on the scalp and elsewhere on the body initially causing bald spots.", "url": "https://disease-ontology.org/term/DOID:986", "evidence": [ { "id": "986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:986" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "histone H3K4me/H3K4me2/H3K4me3 demethylase activity", "id": "GO:0034647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034647", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "histone H3K4 demethylase activity", "id": "GO:0032453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032453", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "rDNA heterochromatin formation", "id": "GO:0000183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000183", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "regulation of chromosome condensation", "id": "GO:0060623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060623", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": "GO:1902275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902275", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "antisense RNA transcript catabolic process", "id": "GO:0071041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071041", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "sporulation", "id": "GO:0043934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043934", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47156-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Ser212", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003880", "url": "https://www.yeastgenome.org/locus/S000003880" }, { "database": "iPTMnet", "id": "P47156", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47156" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P47156-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003880", "url": "https://www.yeastgenome.org/locus/S000003880" }, { "database": "iPTMnet", "id": "P47156", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47156" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P47156-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Ser274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003880", "url": "https://www.yeastgenome.org/locus/S000003880" }, { "database": "iPTMnet", "id": "P47156", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47156" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P47156-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Ser321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47156", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47156" }, { "database": "PubMed", "id": "36167807", "url": "https://glygen.org/publication/PubMed/36167807" }, { "database": "SGD", "id": "S000003880", "url": "https://www.yeastgenome.org/locus/S000003880" } ] } ] }, { "uniprot_canonical_ac": "P47156-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47156", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47156" }, { "database": "PubMed", "id": "36167807", "url": "https://glygen.org/publication/PubMed/36167807" }, { "database": "SGD", "id": "S000003880", "url": "https://www.yeastgenome.org/locus/S000003880" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P47156-1", "start_pos": "711", "end_pos": "711", "site_lbl": "Ser711", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003880", "url": "https://www.yeastgenome.org/locus/S000003880" }, { "database": "iPTMnet", "id": "P47156", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47156" }, { "database": "PubMed", "id": "33334889", "url": "https://glygen.org/publication/PubMed/33334889" }, { "database": "PubMed", "id": "35183557", "url": "https://glygen.org/publication/PubMed/35183557" } ] } ] }, { "uniprot_canonical_ac": "P47156-1", "start_pos": "427", "end_pos": "427", "site_lbl": "His427", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P47156", "url": "https://www.uniprot.org/uniprotkb/P47156" }, { "database": "PubMed", "id": "17310255", "url": "https://glygen.org/publication/PubMed/17310255" } ] } ] } ], "record_id": "P47156-1" }, { "uniprot_canonical_ac": "P47158-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47158", "url": "https://www.uniprot.org/uniprotkb/P47158" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 497, "chemical_mass": 57055.0, "gene_names": "IBA57;CAF17;IBA57;J2043", "protein_name": "Iron-sulfur cluster assembly factor IBA57, mitochondrial", "disease": [ { "disease_id": "DOID:0080135", "name": "multiple mitochondrial dysfunctions syndrome 3", "description": "A multiple mitochondrial dysfunctions syndrome that is characterized by loss of previously acquired developmental milestones in the first months or years of life, and has_material_basis_in autosomal recessive inheritance of homozygous mutation in the iron-sulfur cluster assembly factor IBA57 gene on chromosome 1q42.", "url": "https://disease-ontology.org/term/DOID:0080135", "evidence": [ { "id": "0080135", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080135" } ], "weight": 0.0 }, { "disease_id": "DOID:0110819", "name": "hereditary spastic paraplegia 74", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the IBA57 gene on chromosome 1q42.", "url": "https://disease-ontology.org/term/DOID:0110819", "evidence": [ { "id": "0110819", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110819" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P47158", "url": "https://www.uniprot.org/uniprotkb/P47158" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P47158", "url": "https://www.uniprot.org/uniprotkb/P47158" } ], "pmid": "" } ], "biological_process": [ { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "P47158", "url": "https://www.uniprot.org/uniprotkb/P47158" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47158-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Thr155", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 155, "start_aa": "Thr", "end_pos": 155, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr155", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] } ], "record_id": "P47158-1" }, { "uniprot_canonical_ac": "P47160-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 408, "chemical_mass": 45091.0, "gene_names": "ENT3;ENT3;J2048", "protein_name": "Epsin-3", "disease": [], "biological_process": [ { "name": "multivesicular body sorting pathway", "id": "GO:0071985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071985", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "early endosome to Golgi transport", "id": "GO:0034498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034498", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" } ], "cellular_component": [ { "name": "clathrin vesicle coat", "id": "GO:0030125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030125", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" } ], "molecular_function": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47160-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Tyr13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Ser180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Tyr18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Ser212", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Ser223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Thr226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Ser227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Ser247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Ser251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Ser287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Ser294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Tyr29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Thr30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Thr320", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "342", "end_pos": "342", "site_lbl": "Ser342", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Thr371", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Thr6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003886", "url": "https://www.yeastgenome.org/locus/S000003886" }, { "database": "iPTMnet", "id": "P47160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Phe272", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Reduced binding to GGA2.", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" }, { "database": "PubMed", "id": "12483220", "url": "https://glygen.org/publication/PubMed/12483220" } ] } ] }, { "uniprot_canonical_ac": "P47160-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Phe275", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Reduced binding to GGA2.", "evidence": [ { "database": "UniProtKB", "id": "P47160", "url": "https://www.uniprot.org/uniprotkb/P47160" }, { "database": "PubMed", "id": "12483220", "url": "https://glygen.org/publication/PubMed/12483220" } ] } ] } ], "record_id": "P47160-1" }, { "uniprot_canonical_ac": "P47164-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47164", "url": "https://www.uniprot.org/uniprotkb/P47164" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 639, "chemical_mass": 72351.0, "gene_names": "STR2;J2063;STR2", "protein_name": "Cystathionine gamma-synthase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47164", "url": "https://www.uniprot.org/uniprotkb/P47164" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47164", "url": "https://www.uniprot.org/uniprotkb/P47164" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "P47164", "url": "https://www.uniprot.org/uniprotkb/P47164" } ], "pmid": "" }, { "name": "cystathionine gamma-synthase activity", "id": "GO:0003962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003962", "evidence": [ { "database": "UniProtKB", "id": "P47164", "url": "https://www.uniprot.org/uniprotkb/P47164" } ], "pmid": "" } ], "biological_process": [ { "name": "sulfur compound metabolic process", "id": "GO:0006790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006790", "evidence": [ { "database": "UniProtKB", "id": "P47164", "url": "https://www.uniprot.org/uniprotkb/P47164" } ], "pmid": "" }, { "name": "methionine biosynthetic process", "id": "GO:0009086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009086", "evidence": [ { "database": "UniProtKB", "id": "P47164", "url": "https://www.uniprot.org/uniprotkb/P47164" } ], "pmid": "" }, { "name": "transsulfuration", "id": "GO:0019346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019346", "evidence": [ { "database": "UniProtKB", "id": "P47164", "url": "https://www.uniprot.org/uniprotkb/P47164" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47164-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Thr179", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47164", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47164" } ] } ] }, { "uniprot_canonical_ac": "P47164-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47164" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] } ], "record_id": "P47164-1" }, { "uniprot_canonical_ac": "P47168-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 421, "chemical_mass": 48649.0, "gene_names": "TTI2;J2124;TTI2", "protein_name": "TEL2-interacting protein 2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "pmid": "" }, { "name": "TTT Hsp90 cochaperone complex", "id": "GO:0110078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110078", "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "pmid": "" }, { "name": "cellular response to nutrient levels", "id": "GO:0031669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031669", "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "pmid": "" }, { "name": "cellular response to salt stress", "id": "GO:0071472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071472", "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "pmid": "" }, { "name": "positive regulation of DNA damage checkpoint", "id": "GO:2000003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000003", "evidence": [ { "database": "UniProtKB", "id": "P47168", "url": "https://www.uniprot.org/uniprotkb/P47168" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47168-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47168", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47168" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] } ], "record_id": "P47168-1" }, { "uniprot_canonical_ac": "P47169-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1442, "chemical_mass": 161219.0, "gene_names": "MET5;ECM17;J2126;MET5", "protein_name": "Sulfite reductase [NADPH] subunit beta", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" }, { "name": "sulfite reductase complex (NADPH)", "id": "GO:0009337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009337", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" }, { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" }, { "name": "sulfite reductase (NADPH) activity", "id": "GO:0004783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004783", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" } ], "biological_process": [ { "name": "sulfur amino acid biosynthetic process", "id": "GO:0000097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000097", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" }, { "name": "hydrogen sulfide biosynthetic process", "id": "GO:0070814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070814", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" }, { "name": "sulfate assimilation", "id": "GO:0000103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000103", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47169-1", "start_pos": "1055", "end_pos": "1055", "site_lbl": "Ser1055", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "1133", "end_pos": "1133", "site_lbl": "Ser1133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" }, { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "1298", "end_pos": "1298", "site_lbl": "Ser1298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "1299", "end_pos": "1299", "site_lbl": "Ser1299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "1438", "end_pos": "1438", "site_lbl": "Ser1438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "645", "end_pos": "645", "site_lbl": "Ser645", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" }, { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Ser647", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" }, { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "863", "end_pos": "863", "site_lbl": "Thr863", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" }, { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "865", "end_pos": "865", "site_lbl": "Ser865", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" }, { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "873", "end_pos": "873", "site_lbl": "Ser873", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" }, { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47169-1", "start_pos": "903", "end_pos": "903", "site_lbl": "Ser903", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47169", "url": "https://www.uniprot.org/uniprotkb/P47169" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47169", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47169" }, { "database": "SGD", "id": "S000003898", "url": "https://www.yeastgenome.org/locus/S000003898" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47169-1" }, { "uniprot_canonical_ac": "P47170-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1584, "chemical_mass": 181949.0, "gene_names": "IML1;IML1;J2129;SEA1", "protein_name": "Vacuolar membrane-associated protein IML1", "disease": [ { "disease_id": "DOID:0081421", "name": "familial focal epilepsy with variable foci 1", "description": "A familial focal epilepsy with variable foci that is characterized by focal seizures arising from different cortical regions in different family members and that has_material_basis_in heterozygous mutation in the DEPDC5 gene on chromosome 22q12.", "url": "https://disease-ontology.org/term/DOID:0081421", "evidence": [ { "id": "0081421", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081421" } ], "weight": 0.0 }, { "disease_id": "DOID:0112202", "name": "developmental and epileptic encephalopathy", "description": "An electroclinical syndrome characterized by epileptiform activity and at least one other pathology that together contribute to cognitive and behavioral impairments including developmental delay or regression with onset anywhere from birth to adulthood.", "url": "https://disease-ontology.org/term/DOID:0112202", "evidence": [ { "id": "0112202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112202" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:2234", "name": "focal epilepsy", "description": "An epilepsy syndrome that is characterized by seizures that are preceded by an isolated disturbance of a cerebral function and arise from an epileptic focus, a small portion of the brain that serves as the irritant driving the epileptic response.", "url": "https://disease-ontology.org/term/DOID:2234", "evidence": [ { "id": "2234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2234" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "regulation of autophagosome assembly", "id": "GO:2000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000785", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "regulation of TORC1 signaling", "id": "GO:1903432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903432", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" } ], "cellular_component": [ { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "GATOR1 complex", "id": "GO:1990130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990130", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" }, { "name": "Seh1-associated complex", "id": "GO:0035859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035859", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47170-1", "start_pos": "1285", "end_pos": "1285", "site_lbl": "Thr1285", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1285, "start_aa": "Thr", "end_pos": 1285, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1285", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47170", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47170" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "1287", "end_pos": "1287", "site_lbl": "Ser1287", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1287, "start_aa": "Ser", "end_pos": 1287, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1287", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47170", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47170" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "1291", "end_pos": "1291", "site_lbl": "Thr1291", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "1293", "end_pos": "1293", "site_lbl": "Ser1293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "1303", "end_pos": "1303", "site_lbl": "Ser1303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "1304", "end_pos": "1304", "site_lbl": "Thr1304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "1329", "end_pos": "1329", "site_lbl": "Ser1329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "514", "end_pos": "514", "site_lbl": "Ser514", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "680", "end_pos": "680", "site_lbl": "Ser680", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "701", "end_pos": "701", "site_lbl": "Ser701", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "737", "end_pos": "737", "site_lbl": "Ser737", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47170", "url": "https://www.uniprot.org/uniprotkb/P47170" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "741", "end_pos": "741", "site_lbl": "Ser741", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "743", "end_pos": "743", "site_lbl": "Thr743", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "753", "end_pos": "753", "site_lbl": "Ser753", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "794", "end_pos": "794", "site_lbl": "Ser794", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "808", "end_pos": "808", "site_lbl": "Ser808", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "811", "end_pos": "811", "site_lbl": "Ser811", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "814", "end_pos": "814", "site_lbl": "Ser814", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "826", "end_pos": "826", "site_lbl": "Ser826", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "831", "end_pos": "831", "site_lbl": "Ser831", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "833", "end_pos": "833", "site_lbl": "Thr833", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "835", "end_pos": "835", "site_lbl": "Ser835", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47170-1", "start_pos": "845", "end_pos": "845", "site_lbl": "Ser845", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003899", "url": "https://www.yeastgenome.org/locus/S000003899" }, { "database": "iPTMnet", "id": "P47170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47170-1" }, { "uniprot_canonical_ac": "P47171-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1648, "chemical_mass": 191680.0, "gene_names": "HIR3;HIR3;HPC1;J2161", "protein_name": "Histone transcription regulator 3", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": "GO:1902275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902275", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "pmid": "" }, { "name": "HIR complex", "id": "GO:0000417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000417", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47171-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Thr302", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47171", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47171" }, { "database": "SGD", "id": "S000003901", "url": "https://www.yeastgenome.org/locus/S000003901" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47171-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Ser304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47171", "url": "https://www.uniprot.org/uniprotkb/P47171" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47171", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47171" }, { "database": "SGD", "id": "S000003901", "url": "https://www.yeastgenome.org/locus/S000003901" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47171-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Ser320", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003901", "url": "https://www.yeastgenome.org/locus/S000003901" }, { "database": "iPTMnet", "id": "P47171", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47171" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47171-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003901", "url": "https://www.yeastgenome.org/locus/S000003901" }, { "database": "iPTMnet", "id": "P47171", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47171" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47171-1" }, { "uniprot_canonical_ac": "P47176-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 376, "chemical_mass": 41625.0, "gene_names": "BAT2;BAT2;ECA40;J2209;TWT2", "protein_name": "Branched-chain-amino-acid aminotransferase, cytosolic", "disease": [ { "disease_id": "DOID:0060950", "name": "hypervalinemia and hyperleucine-isoleucinemia", "description": "An amino acid metabolic characterized by highly elevated plasma valine and leucine concentrations that has_material_basis_in compound heterozygous mutation in the BCAT2 gene on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0060950", "evidence": [ { "id": "0060950", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060950" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 }, { "disease_id": "DOID:9269", "name": "maple syrup urine disease", "description": "An organic acidemia that is caused by a deficiency of decarboxylase leading to high concentrations of valine, leucine, isoleucine, and alloisoleucine in the blood, urine, and cerebrospinal fluid and characterized by an odor of maple syrup to the urine, vomiting, hypertonicity, severe mental retardation, seizures, and eventually death unless the condition is treated with dietary measures.", "url": "https://disease-ontology.org/term/DOID:9269", "evidence": [ { "id": "9269", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9269" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" } ], "biological_process": [ { "name": "branched-chain amino acid catabolic process", "id": "GO:0009083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009083", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "L-methionine salvage from methylthioadenosine", "id": "GO:0019509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019509", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "branched-chain amino acid biosynthetic process", "id": "GO:0009082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009082", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "L-leucine biosynthetic process", "id": "GO:0009098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009098", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "L-valine biosynthetic process", "id": "GO:0009099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009099", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "isoleucine biosynthetic process", "id": "GO:0009097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009097", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" } ], "molecular_function": [ { "name": "branched-chain-amino-acid transaminase activity", "id": "GO:0004084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004084", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "L-leucine-2-oxoglutarate transaminase activity", "id": "GO:0052654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052654", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "L-valine-2-oxoglutarate transaminase activity", "id": "GO:0052655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052655", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "L-isoleucine-2-oxoglutarate transaminase activity", "id": "GO:0052656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052656", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" }, { "name": "methionine-oxo-acid transaminase activity", "id": "GO:0010326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010326", "evidence": [ { "database": "UniProtKB", "id": "P47176", "url": "https://www.uniprot.org/uniprotkb/P47176" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47176-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Thr15", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 15, "start_aa": "Thr", "end_pos": 15, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr15", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47176", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47176" } ] } ] }, { "uniprot_canonical_ac": "P47176-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Thr16", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47176", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47176" } ] } ] }, { "uniprot_canonical_ac": "P47176-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 20, "start_aa": "Ser", "end_pos": 20, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser20", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P47176", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P47176" } ] } ] }, { "uniprot_canonical_ac": "P47176-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003909", "url": "https://www.yeastgenome.org/locus/S000003909" }, { "database": "iPTMnet", "id": "P47176", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47176" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47176-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Ser322", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003909", "url": "https://www.yeastgenome.org/locus/S000003909" }, { "database": "iPTMnet", "id": "P47176", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47176" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47176-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003909", "url": "https://www.yeastgenome.org/locus/S000003909" }, { "database": "iPTMnet", "id": "P47176", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47176" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47176-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Thr51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47176", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47176" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003909", "url": "https://www.yeastgenome.org/locus/S000003909" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47176-1" }, { "uniprot_canonical_ac": "P47178-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47178", "url": "https://www.uniprot.org/uniprotkb/P47178" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 298, "chemical_mass": 29606.0, "gene_names": "DAN1;CCW13;DAN1;J2217", "protein_name": "Cell wall protein DAN1", "disease": [], "cellular_component": [ { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P47178", "url": "https://www.uniprot.org/uniprotkb/P47178" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P47178", "url": "https://www.uniprot.org/uniprotkb/P47178" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P47178", "url": "https://www.uniprot.org/uniprotkb/P47178" } ], "pmid": "" } ], "biological_process": [ { "name": "sterol transport", "id": "GO:0015918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015918", "evidence": [ { "database": "UniProtKB", "id": "P47178", "url": "https://www.uniprot.org/uniprotkb/P47178" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P47178", "url": "https://www.uniprot.org/uniprotkb/P47178" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of cell wall", "id": "GO:0005199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005199", "evidence": [ { "database": "UniProtKB", "id": "P47178", "url": "https://www.uniprot.org/uniprotkb/P47178" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P47178-1" }, { "uniprot_canonical_ac": "P47818-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 322, "chemical_mass": 34250.0, "gene_names": "CCC1;CCC1;L8083.6", "protein_name": "Protein CCC1", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" }, { "name": "manganese ion transport", "id": "GO:0006828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006828", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" }, { "name": "intracellular manganese ion homeostasis", "id": "GO:0030026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030026", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" }, { "name": "detoxification of iron ion", "id": "GO:1990461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990461", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" } ], "molecular_function": [ { "name": "manganese ion transmembrane transporter activity", "id": "GO:0005384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005384", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" }, { "name": "ferrous iron transmembrane transporter activity", "id": "GO:0015093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015093", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" }, { "name": "iron ion transmembrane transporter activity", "id": "GO:0005381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005381", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47818-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Thr32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47818-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Ser83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47818", "url": "https://www.uniprot.org/uniprotkb/P47818" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P47818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47818" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004210", "url": "https://www.yeastgenome.org/locus/S000004210" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47818-1" }, { "uniprot_canonical_ac": "P47821-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 323, "chemical_mass": 37791.0, "gene_names": "SSN8;CNC1;GIG3;N2805;NUT9;RYE2;SRB11;SSN8;UME3", "protein_name": "RNA polymerase II holoenzyme cyclin-like subunit", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "pmid": "" }, { "name": "positive regulation of transcription by galactose", "id": "GO:0000411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000411", "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II core promoter sequence-specific DNA binding", "id": "GO:0000979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000979", "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "P47821", "url": "https://www.uniprot.org/uniprotkb/P47821" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47821-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004970", "url": "https://www.yeastgenome.org/locus/S000004970" }, { "database": "iPTMnet", "id": "P47821", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47821" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "24554767", "url": "https://glygen.org/publication/PubMed/24554767" }, { "database": "PubMed", "id": "33933450", "url": "https://glygen.org/publication/PubMed/33933450" } ] } ] } ], "record_id": "P47821-1" }, { "uniprot_canonical_ac": "P47822-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 140, "chemical_mass": 16071.0, "gene_names": "SRB7;D9740.17;MED21;SRB7;SSX1", "protein_name": "Mediator of RNA polymerase II transcription subunit 21", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47822-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47822", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47822" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P47822-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ala21", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "T", "comment": "In SRB7-1; suppresses the phenotypic defects of an RNA polymerase IICTD truncation.", "evidence": [ { "database": "UniProtKB", "id": "P47822", "url": "https://www.uniprot.org/uniprotkb/P47822" }, { "database": "PubMed", "id": "7774808", "url": "https://glygen.org/publication/PubMed/7774808" } ] } ] } ], "record_id": "P47822-1" }, { "uniprot_canonical_ac": "P47912-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 694, "chemical_mass": 77267.0, "gene_names": "FAA4;FAA4;YM9408.08", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "disease": [ { "disease_id": "DOID:0050776", "name": "non-syndromic X-linked intellectual disability", "description": "A non-syndromic intellectual disability characterized by a X-linked inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0050776", "evidence": [ { "id": "0050776", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050776" } ], "weight": 0.0 }, { "disease_id": "DOID:0112050", "name": "non-syndromic X-linked intellectual disability 63", "description": "A non-syndromic X-linked intellectual disability characterized by moderate to severe nonprogressive intellectual disability in males and moderate intellectual disability to normal intelligence in females that has_material_basis_in heterozygous mutation in the ACSL4 gene on chromosome Xq23.", "url": "https://disease-ontology.org/term/DOID:0112050", "evidence": [ { "id": "0112050", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112050" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:14501", "name": "Sjogren-Larsson syndrome", "description": "A syndrome that is characterized by ichthyosis, mental retardation, spastic paraparesis, macular dystrophy, and leukoencephalopathy, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the aldehyde dehydrogenase 3 family member A2 (ALDH3A2) gene, which encodes fatty aldehyde dehydrogenase, on chromosome 17p11.", "url": "https://disease-ontology.org/term/DOID:14501", "evidence": [ { "id": "14501", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14501" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 } ], "biological_process": [ { "name": "long-chain fatty acid metabolic process", "id": "GO:0001676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001676", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" }, { "name": "long-chain fatty acid import into cell", "id": "GO:0044539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044539", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" }, { "name": "long-chain fatty-acyl-CoA metabolic process", "id": "GO:0035336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035336", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" }, { "name": "sphingoid long-chain base transport", "id": "GO:1905329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905329", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" }, { "name": "long-chain fatty acid-CoA ligase activity", "id": "GO:0004467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004467", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P47912", "url": "https://www.uniprot.org/uniprotkb/P47912" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47912-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Thr305", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 305, "start_aa": "Thr", "end_pos": 305, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr305", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P47912-1", "start_pos": "342", "end_pos": "342", "site_lbl": "Thr342", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004860", "url": "https://www.yeastgenome.org/locus/S000004860" }, { "database": "iPTMnet", "id": "P47912", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47912" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47912-1", "start_pos": "480", "end_pos": "480", "site_lbl": "Thr480", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004860", "url": "https://www.yeastgenome.org/locus/S000004860" }, { "database": "iPTMnet", "id": "P47912", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47912" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47912-1", "start_pos": "482", "end_pos": "482", "site_lbl": "Thr482", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004860", "url": "https://www.yeastgenome.org/locus/S000004860" }, { "database": "iPTMnet", "id": "P47912", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47912" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P47912-1", "start_pos": "532", "end_pos": "532", "site_lbl": "Thr532", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004860", "url": "https://www.yeastgenome.org/locus/S000004860" }, { "database": "iPTMnet", "id": "P47912", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47912" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47912-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Thr539", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004860", "url": "https://www.yeastgenome.org/locus/S000004860" }, { "database": "iPTMnet", "id": "P47912", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47912" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P47912-1" }, { "uniprot_canonical_ac": "P47977-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 285, "chemical_mass": 32314.0, "gene_names": "TIS11;CTH2;L3143;L9606.12;TIS11", "protein_name": "mRNA decay factor CTH2", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" }, { "name": "translation repressor activity", "id": "GO:0030371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030371", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" }, { "name": "negative regulation of cytoplasmic translation", "id": "GO:2000766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000766", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" }, { "name": "electron transport coupled proton transport", "id": "GO:0015990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015990", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial translation", "id": "GO:0070130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070130", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" }, { "name": "response to iron ion starvation", "id": "GO:1990641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990641", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47977-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004126", "url": "https://www.yeastgenome.org/locus/S000004126" }, { "database": "iPTMnet", "id": "P47977", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47977" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P47977-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47977", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47977" }, { "database": "PubMed", "id": "30228242", "url": "https://glygen.org/publication/PubMed/30228242" }, { "database": "SGD", "id": "S000004126", "url": "https://www.yeastgenome.org/locus/S000004126" } ] } ] }, { "uniprot_canonical_ac": "P47977-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47977", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47977" }, { "database": "PubMed", "id": "30228242", "url": "https://glygen.org/publication/PubMed/30228242" }, { "database": "SGD", "id": "S000004126", "url": "https://www.yeastgenome.org/locus/S000004126" } ] } ] }, { "uniprot_canonical_ac": "P47977-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47977", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47977" }, { "database": "PubMed", "id": "30228242", "url": "https://glygen.org/publication/PubMed/30228242" }, { "database": "SGD", "id": "S000004126", "url": "https://www.yeastgenome.org/locus/S000004126" } ] } ] }, { "uniprot_canonical_ac": "P47977-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P47977", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47977" }, { "database": "PubMed", "id": "30228242", "url": "https://glygen.org/publication/PubMed/30228242" }, { "database": "SGD", "id": "S000004126", "url": "https://www.yeastgenome.org/locus/S000004126" } ] } ] }, { "uniprot_canonical_ac": "P47977-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Cys190", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Abolishes mRNA binding.", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" }, { "database": "PubMed", "id": "15652485", "url": "https://glygen.org/publication/PubMed/15652485" } ] }, { "sequence_org": "C", "sequence_mut": "R", "comment": "Abolishes mRNA binding.", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" }, { "database": "PubMed", "id": "15652485", "url": "https://glygen.org/publication/PubMed/15652485" } ] } ] }, { "uniprot_canonical_ac": "P47977-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Cys213", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Abolishes mRNA binding.", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" }, { "database": "PubMed", "id": "15652485", "url": "https://glygen.org/publication/PubMed/15652485" } ] }, { "sequence_org": "C", "sequence_mut": "R", "comment": "Abolishes mRNA binding.", "evidence": [ { "database": "UniProtKB", "id": "P47977", "url": "https://www.uniprot.org/uniprotkb/P47977" }, { "database": "PubMed", "id": "15652485", "url": "https://glygen.org/publication/PubMed/15652485" } ] } ] } ], "record_id": "P47977-1" }, { "uniprot_canonical_ac": "P48016-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1211, "chemical_mass": 136921.0, "gene_names": "ATH1;ATH1;YP9367.06", "protein_name": "Periplasmic acid trehalase ATH1", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" }, { "name": "fungal-type vacuole lumen", "id": "GO:0000328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000328", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" }, { "name": "cell wall-bounded periplasmic space", "id": "GO:0030287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030287", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" }, { "name": "alpha,alpha-trehalase activity", "id": "GO:0004555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004555", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" } ], "biological_process": [ { "name": "trehalose catabolic process", "id": "GO:0005993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005993", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" }, { "name": "trehalose transport", "id": "GO:0015771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015771", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" }, { "name": "carbon utilization", "id": "GO:0015976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015976", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48016-1", "start_pos": "1031", "end_pos": "1031", "site_lbl": "Asn1031", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1031, "start_aa": "Asn", "end_pos": 1031, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1031", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "1049", "end_pos": "1049", "site_lbl": "Asn1049", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1049, "start_aa": "Asn", "end_pos": 1049, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1049", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "1064", "end_pos": "1064", "site_lbl": "Asn1064", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1064, "start_aa": "Asn", "end_pos": 1064, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1064", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "1147", "end_pos": "1147", "site_lbl": "Asn1147", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1147, "start_aa": "Asn", "end_pos": 1147, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1147", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "1157", "end_pos": "1157", "site_lbl": "Asn1157", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1157, "start_aa": "Asn", "end_pos": 1157, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1157", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Asn207", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 207, "start_aa": "Asn", "end_pos": 207, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn207", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Asn238", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 238, "start_aa": "Asn", "end_pos": 238, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn238", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Asn247", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 247, "start_aa": "Asn", "end_pos": 247, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn247", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Asn255", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 255, "start_aa": "Asn", "end_pos": 255, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn255", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Asn259", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 259, "start_aa": "Asn", "end_pos": 259, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn259", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Asn325", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 325, "start_aa": "Asn", "end_pos": 325, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn325", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Asn370", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 370, "start_aa": "Asn", "end_pos": 370, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn370", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Asn376", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 376, "start_aa": "Asn", "end_pos": 376, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn376", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Asn488", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 488, "start_aa": "Asn", "end_pos": 488, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn488", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Asn539", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 539, "start_aa": "Asn", "end_pos": 539, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn539", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "568", "end_pos": "568", "site_lbl": "Asn568", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 568, "start_aa": "Asn", "end_pos": 568, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn568", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "628", "end_pos": "628", "site_lbl": "Asn628", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 628, "start_aa": "Asn", "end_pos": 628, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn628", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "638", "end_pos": "638", "site_lbl": "Asn638", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 638, "start_aa": "Asn", "end_pos": 638, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn638", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "696", "end_pos": "696", "site_lbl": "Asn696", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 696, "start_aa": "Asn", "end_pos": 696, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn696", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "705", "end_pos": "705", "site_lbl": "Asn705", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 705, "start_aa": "Asn", "end_pos": 705, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn705", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "879", "end_pos": "879", "site_lbl": "Asn879", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 879, "start_aa": "Asn", "end_pos": 879, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn879", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "897", "end_pos": "897", "site_lbl": "Asn897", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 897, "start_aa": "Asn", "end_pos": 897, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn897", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "910", "end_pos": "910", "site_lbl": "Asn910", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 910, "start_aa": "Asn", "end_pos": 910, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn910", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "972", "end_pos": "972", "site_lbl": "Asn972", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 972, "start_aa": "Asn", "end_pos": 972, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn972", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Asn98", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 98, "start_aa": "Asn", "end_pos": 98, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn98", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "990", "end_pos": "990", "site_lbl": "Asn990", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 990, "start_aa": "Asn", "end_pos": 990, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn990", "evidence": [ { "id": "P48016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "1192", "end_pos": "1192", "site_lbl": "Tyr1192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48016" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "1195", "end_pos": "1195", "site_lbl": "Tyr1195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48016" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "622", "end_pos": "622", "site_lbl": "Thr622", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006230", "url": "https://www.yeastgenome.org/locus/S000006230" }, { "database": "iPTMnet", "id": "P48016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Lys27", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes its ubiquitination; when associated with R-27 and R-37. Normal protein targeting to vacuolar lumen; when associated with R-2 and R-37.", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" }, { "database": "PubMed", "id": "17475771", "url": "https://glygen.org/publication/PubMed/17475771" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Lys2", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes its ubiquitination; when associated with R-27 and R-37. Normal protein targeting to vacuolar lumen; when associated with R-27 and R-37.", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" }, { "database": "PubMed", "id": "17475771", "url": "https://glygen.org/publication/PubMed/17475771" } ] } ] }, { "uniprot_canonical_ac": "P48016-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Lys37", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes its ubiquitination; when associated with R-27 and R-37. Normal protein targeting to vacuolar lumen; when associated with R-2 and R-27.", "evidence": [ { "database": "UniProtKB", "id": "P48016", "url": "https://www.uniprot.org/uniprotkb/P48016" }, { "database": "PubMed", "id": "17475771", "url": "https://glygen.org/publication/PubMed/17475771" } ] } ] } ], "record_id": "P48016-1" }, { "uniprot_canonical_ac": "P48164-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 190, "chemical_mass": 21634.0, "gene_names": "RPS7B;N2212;RPS7B", "protein_name": "Small ribosomal subunit protein eS7B", "disease": [ { "disease_id": "DOID:0111881", "name": "Diamond-Blackfan anemia 8", "description": "A Diamond-Blackfan anemia that has_material_basis_in heterozygous mutation in the RPS7 gene on chromosome 2p25.3.", "url": "https://disease-ontology.org/term/DOID:0111881", "evidence": [ { "id": "0111881", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111881" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48164-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Thr117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Thr119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "30377154", "url": "https://glygen.org/publication/PubMed/30377154" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Thr23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48164", "url": "https://www.uniprot.org/uniprotkb/P48164" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Thr52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48164-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005040", "url": "https://www.yeastgenome.org/locus/S000005040" }, { "database": "iPTMnet", "id": "P48164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P48164-1" }, { "uniprot_canonical_ac": "P48231-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1178, "chemical_mass": 132509.0, "gene_names": "TCB2;N2250;TCB2", "protein_name": "Tricalbin-2", "disease": [], "biological_process": [ { "name": "endoplasmic reticulum membrane organization", "id": "GO:0090158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090158", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" }, { "name": "regulation of phosphatidylinositol dephosphorylation", "id": "GO:0060304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060304", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" }, { "name": "ER to Golgi ceramide transport", "id": "GO:0035621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035621", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane tethering", "id": "GO:0061817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061817", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" }, { "name": "cortical endoplasmic reticulum", "id": "GO:0032541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032541", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48231-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Thr10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005031", "url": "https://www.yeastgenome.org/locus/S000005031" }, { "database": "iPTMnet", "id": "P48231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48231" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48231-1", "start_pos": "1174", "end_pos": "1174", "site_lbl": "Ser1174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005031", "url": "https://www.yeastgenome.org/locus/S000005031" }, { "database": "iPTMnet", "id": "P48231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48231" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P48231-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Thr133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48231" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P48231-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Ser140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48231" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P48231-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48231" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005031", "url": "https://www.yeastgenome.org/locus/S000005031" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48231-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48231" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005031", "url": "https://www.yeastgenome.org/locus/S000005031" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48231-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Thr23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005031", "url": "https://www.yeastgenome.org/locus/S000005031" }, { "database": "iPTMnet", "id": "P48231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48231" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48231-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Thr43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005031", "url": "https://www.yeastgenome.org/locus/S000005031" }, { "database": "iPTMnet", "id": "P48231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48231" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48231-1", "start_pos": "991", "end_pos": "991", "site_lbl": "Ser991", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48231", "url": "https://www.uniprot.org/uniprotkb/P48231" }, { "database": "SGD", "id": "S000005031", "url": "https://www.yeastgenome.org/locus/S000005031" }, { "database": "iPTMnet", "id": "P48231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48231" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P48231-1" }, { "uniprot_canonical_ac": "P48236-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48236", "url": "https://www.uniprot.org/uniprotkb/P48236" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 432, "chemical_mass": 51647.0, "gene_names": "GPC1;G6639;GPC1", "protein_name": "Glycerophosphocholine acyltransferase 1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P48236", "url": "https://www.uniprot.org/uniprotkb/P48236" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P48236", "url": "https://www.uniprot.org/uniprotkb/P48236" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P48236", "url": "https://www.uniprot.org/uniprotkb/P48236" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylcholine biosynthetic process", "id": "GO:0006656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006656", "evidence": [ { "database": "UniProtKB", "id": "P48236", "url": "https://www.uniprot.org/uniprotkb/P48236" } ], "pmid": "" }, { "name": "phosphatidylcholine acyl-chain remodeling", "id": "GO:0036151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036151", "evidence": [ { "database": "UniProtKB", "id": "P48236", "url": "https://www.uniprot.org/uniprotkb/P48236" } ], "pmid": "" }, { "name": "phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine", "id": "GO:0090640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090640", "evidence": [ { "database": "UniProtKB", "id": "P48236", "url": "https://www.uniprot.org/uniprotkb/P48236" } ], "pmid": "" } ], "molecular_function": [ { "name": "glycero-3-phosphocholine acyltransferase activity", "id": "GO:0106158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106158", "evidence": [ { "database": "UniProtKB", "id": "P48236", "url": "https://www.uniprot.org/uniprotkb/P48236" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48236-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Ser398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48236" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P48236-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Ser403", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48236" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003381", "url": "https://www.yeastgenome.org/locus/S000003381" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48236-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Ser406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48236" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003381", "url": "https://www.yeastgenome.org/locus/S000003381" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48236-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Tyr412", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003381", "url": "https://www.yeastgenome.org/locus/S000003381" }, { "database": "iPTMnet", "id": "P48236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48236" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48236-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48236" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003381", "url": "https://www.yeastgenome.org/locus/S000003381" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48236-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48236", "url": "https://www.uniprot.org/uniprotkb/P48236" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P48236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48236" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003381", "url": "https://www.yeastgenome.org/locus/S000003381" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P48236-1" }, { "uniprot_canonical_ac": "P48237-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 864, "chemical_mass": 101423.0, "gene_names": "CCM1;CCM1;DMR1;G6642;RRG2", "protein_name": "Mitochondrial 15S rRNA processing factor CCM1", "disease": [], "biological_process": [ { "name": "positive regulation of rRNA processing", "id": "GO:2000234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000234", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "pmid": "" }, { "name": "mitochondrial RNA processing", "id": "GO:0000963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000963", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "pmid": "" }, { "name": "rRNA metabolic process", "id": "GO:0016072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016072", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48237-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Thr351", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "In dmr1-2; mildly impairs respiratory growth and has almost wild-type mitochondrial protein synthesis; when associated with V-785.", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" }, { "database": "PubMed", "id": "21546354", "url": "https://glygen.org/publication/PubMed/21546354" } ] } ] }, { "uniprot_canonical_ac": "P48237-1", "start_pos": "785", "end_pos": "785", "site_lbl": "Asp785", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "V", "comment": "In dmr1-1; impairs respiratory growth and mitochondrial protein synthesis. In dmr1-2; mildly impairs respiratory growth and has almost wild-type mitochondrial protein synthesis; when associated with A-351.", "evidence": [ { "database": "UniProtKB", "id": "P48237", "url": "https://www.uniprot.org/uniprotkb/P48237" }, { "database": "PubMed", "id": "21546354", "url": "https://glygen.org/publication/PubMed/21546354" } ] } ] } ], "record_id": "P48237-1" }, { "uniprot_canonical_ac": "P48240-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 250, "chemical_mass": 27577.0, "gene_names": "MTR3;G6676;MTR3", "protein_name": "Exosome complex component MTR3", "disease": [], "biological_process": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "poly(A)-dependent snoRNA 3'-end processing", "id": "GO:0071051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071051", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent CUT catabolic process", "id": "GO:0071039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071039", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "P48240", "url": "https://www.uniprot.org/uniprotkb/P48240" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48240-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Thr148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48240", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48240" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P48240-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003390", "url": "https://www.yeastgenome.org/locus/S000003390" }, { "database": "iPTMnet", "id": "P48240", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48240" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48240-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Ser243", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48240", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48240" }, { "database": "PubMed", "id": "16829593", "url": "https://glygen.org/publication/PubMed/16829593" } ] } ] }, { "uniprot_canonical_ac": "P48240-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003390", "url": "https://www.yeastgenome.org/locus/S000003390" }, { "database": "iPTMnet", "id": "P48240", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48240" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48240-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Thr36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48240", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48240" }, { "database": "PubMed", "id": "16829593", "url": "https://glygen.org/publication/PubMed/16829593" }, { "database": "SGD", "id": "S000003390", "url": "https://www.yeastgenome.org/locus/S000003390" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48240-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003390", "url": "https://www.yeastgenome.org/locus/S000003390" }, { "database": "iPTMnet", "id": "P48240", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48240" }, { "database": "PubMed", "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345" } ] } ] } ], "record_id": "P48240-1" }, { "uniprot_canonical_ac": "P48360-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48360", "url": "https://www.uniprot.org/uniprotkb/P48360" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 493, "chemical_mass": 56237.0, "gene_names": "ARH1;ARH1;D9481.5", "protein_name": "Probable NADPH:adrenodoxin oxidoreductase, mitochondrial", "disease": [ { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:2742", "name": "auditory system disease", "description": "A sensory system disease that is characterized by auditory dysfunction located_in the auditory system.", "url": "https://disease-ontology.org/term/DOID:2742", "evidence": [ { "id": "2742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2742" } ], "weight": 0.0 }, { "disease_id": "DOID:5723", "name": "optic atrophy", "description": "An optic nerve disease that is characterized the death of the retinal ganglion cell axons that comprise the optic nerve.", "url": "https://disease-ontology.org/term/DOID:5723", "evidence": [ { "id": "5723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5723" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P48360", "url": "https://www.uniprot.org/uniprotkb/P48360" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P48360", "url": "https://www.uniprot.org/uniprotkb/P48360" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P48360", "url": "https://www.uniprot.org/uniprotkb/P48360" } ], "pmid": "" }, { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "P48360", "url": "https://www.uniprot.org/uniprotkb/P48360" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "P48360", "url": "https://www.uniprot.org/uniprotkb/P48360" } ], "pmid": "" }, { "name": "ferredoxin-NADP+ reductase activity", "id": "GO:0004324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004324", "evidence": [ { "database": "UniProtKB", "id": "P48360", "url": "https://www.uniprot.org/uniprotkb/P48360" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P48360-1" }, { "uniprot_canonical_ac": "P48363-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48363", "url": "https://www.uniprot.org/uniprotkb/P48363" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 199, "chemical_mass": 23115.0, "gene_names": "PAC10;GIM2;PAC10;PFD3;RKS2", "protein_name": "Prefoldin subunit 3", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P48363", "url": "https://www.uniprot.org/uniprotkb/P48363" } ], "pmid": "" }, { "name": "prefoldin complex", "id": "GO:0016272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016272", "evidence": [ { "database": "UniProtKB", "id": "P48363", "url": "https://www.uniprot.org/uniprotkb/P48363" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P48363", "url": "https://www.uniprot.org/uniprotkb/P48363" } ], "pmid": "" }, { "name": "tubulin complex assembly", "id": "GO:0007021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007021", "evidence": [ { "database": "UniProtKB", "id": "P48363", "url": "https://www.uniprot.org/uniprotkb/P48363" } ], "pmid": "" }, { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "P48363", "url": "https://www.uniprot.org/uniprotkb/P48363" } ], "pmid": "" } ], "molecular_function": [ { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "P48363", "url": "https://www.uniprot.org/uniprotkb/P48363" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48363-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Ser89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003310", "url": "https://www.yeastgenome.org/locus/S000003310" }, { "database": "iPTMnet", "id": "P48363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48363" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P48363-1" }, { "uniprot_canonical_ac": "P48412-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 387, "chemical_mass": 44924.0, "gene_names": "UPF3;SUA6;SUP112;UPF3", "protein_name": "Nonsense-mediated mRNA decay protein 3", "disease": [ { "disease_id": "DOID:0060821", "name": "syndromic X-linked intellectual disability 14", "description": "A syndromic X-linked intellectual disability characterized by mild to severe intellectual disability, autistic features, slender build, poor musculature, long, thin face, high-arched palate, high nasal bridge, and pectus deformities that has_material_basis_in mutation in the UPF3B gene on chromosome Xq24.", "url": "https://disease-ontology.org/term/DOID:0060821", "evidence": [ { "id": "0060821", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060821" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay", "id": "GO:0070478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070478", "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "pmid": "" }, { "name": "cytoplasmic RNA surveillance", "id": "GO:0071026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071026", "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P48412", "url": "https://www.uniprot.org/uniprotkb/P48412" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48412-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003304", "url": "https://www.yeastgenome.org/locus/S000003304" }, { "database": "iPTMnet", "id": "P48412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48412" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48412-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003304", "url": "https://www.yeastgenome.org/locus/S000003304" }, { "database": "iPTMnet", "id": "P48412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48412" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P48412-1" }, { "uniprot_canonical_ac": "P48439-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48439", "url": "https://www.uniprot.org/uniprotkb/P48439" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 350, "chemical_mass": 39483.0, "gene_names": "OST3;OST3;YOR3124W", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3", "disease": [ { "disease_id": "DOID:0080319", "name": "X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia", "description": "A T cell deficiency that is characterized by CD4 lymphopenia, severe chronic viral infections, and defective T-lymphocyte activation in males and has_material_basis_in X-linked inheritance of mutations in the gene encoding magnesium transporter-1 (MAGT1).", "url": "https://disease-ontology.org/term/DOID:0080319", "evidence": [ { "id": "0080319", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080319" } ], "weight": 0.0 }, { "disease_id": "DOID:0081183", "name": "autosomal recessive intellectual developmental disorder 7", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the TUSC3 gene on chromosome 8p22.", "url": "https://disease-ontology.org/term/DOID:0081183", "evidence": [ { "id": "0081183", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081183" } ], "weight": 0.0 }, { "disease_id": "DOID:0111839", "name": "congenital disorder of glycosylation Icc", "description": "A congenital disorder of glycosylation type I characterized by developmental delay, impaired intellectual development, and mild facial dysmorphism associated with abnormal serum transferrin isoelectic focusing consistent with a type 1 pattern that has_material_basis_in hemizygous mutation in the MAGT1 gene on chromosome Xq21.1.", "url": "https://disease-ontology.org/term/DOID:0111839", "evidence": [ { "id": "0111839", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111839" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:104", "name": "bacterial infectious disease", "description": "A disease by infectious agent that results_in infection, has_material_basis_in Bacteria.", "url": "https://disease-ontology.org/term/DOID:104", "evidence": [ { "id": "104", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:104" } ], "weight": 0.0 }, { "disease_id": "DOID:612", "name": "primary immunodeficiency disease", "description": "An immune system disease that results when one or more essential parts of the immune system is missing or not working properly at birth due to a genetic mutation.", "url": "https://disease-ontology.org/term/DOID:612", "evidence": [ { "id": "612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:612" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P48439", "url": "https://www.uniprot.org/uniprotkb/P48439" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P48439", "url": "https://www.uniprot.org/uniprotkb/P48439" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P48439", "url": "https://www.uniprot.org/uniprotkb/P48439" } ], "pmid": "" }, { "name": "oligosaccharyltransferase complex", "id": "GO:0008250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008250", "evidence": [ { "database": "UniProtKB", "id": "P48439", "url": "https://www.uniprot.org/uniprotkb/P48439" } ], "pmid": "" } ], "biological_process": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "P48439", "url": "https://www.uniprot.org/uniprotkb/P48439" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "P48439", "url": "https://www.uniprot.org/uniprotkb/P48439" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "P48439", "url": "https://www.uniprot.org/uniprotkb/P48439" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "P48439", "url": "https://www.uniprot.org/uniprotkb/P48439" } ], "pmid": "" }, { "name": "dolichyl-diphosphooligosaccharide-protein glycotransferase activity", "id": "GO:0004579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004579", "evidence": [ { "database": "UniProtKB", "id": "P48439", "url": "https://www.uniprot.org/uniprotkb/P48439" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P48439-1" }, { "uniprot_canonical_ac": "P48445-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48445", "url": "https://www.uniprot.org/uniprotkb/P48445" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 690, "chemical_mass": 76363.0, "gene_names": "BPL1;ACC2;BPL1;D2140", "protein_name": "Biotin--protein ligase", "disease": [ { "disease_id": "DOID:859", "name": "holocarboxylase synthetase deficiency", "description": "A multiple carboxylase deficiency that involves a deficiency in holocarboxylase synthetase.", "url": "https://disease-ontology.org/term/DOID:859", "evidence": [ { "id": "859", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:859" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P48445", "url": "https://www.uniprot.org/uniprotkb/P48445" } ], "pmid": "" }, { "name": "biotin--[biotin carboxyl-carrier protein] ligase activity", "id": "GO:0004077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004077", "evidence": [ { "database": "UniProtKB", "id": "P48445", "url": "https://www.uniprot.org/uniprotkb/P48445" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P48445", "url": "https://www.uniprot.org/uniprotkb/P48445" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P48445", "url": "https://www.uniprot.org/uniprotkb/P48445" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48445-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Thr12", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P48445-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48445", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48445" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002300", "url": "https://www.yeastgenome.org/locus/S000002300" } ] } ] } ], "record_id": "P48445-1" }, { "uniprot_canonical_ac": "P48558-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 297, "chemical_mass": 33645.0, "gene_names": "BXI1;BXI1;N0405;YBH3", "protein_name": "Bax inhibitor 1", "disease": [ { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "P48558", "url": "https://www.uniprot.org/uniprotkb/P48558" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48558-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005249", "url": "https://www.yeastgenome.org/locus/S000005249" }, { "database": "iPTMnet", "id": "P48558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P48558-1" }, { "uniprot_canonical_ac": "P48559-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 417, "chemical_mass": 47116.0, "gene_names": "YPT11;N0410;YPT11", "protein_name": "GTP-binding protein YPT11", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "myosin V binding", "id": "GO:0031489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031489", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "lipid droplet organization", "id": "GO:0034389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034389", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "mitochondrion localization", "id": "GO:0051646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051646", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "intracellular distribution of mitochondria", "id": "GO:0048312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048312", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "Golgi inheritance", "id": "GO:0048313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048313", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "mitochondrion inheritance", "id": "GO:0000001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000001", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "endoplasmic reticulum inheritance", "id": "GO:0048309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048309", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" }, { "name": "Golgi distribution to daughter cells", "id": "GO:0090167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090167", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48559-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Thr21", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 21, "start_aa": "Thr", "end_pos": 21, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr21", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Ser261", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 261, "start_aa": "Ser", "end_pos": 261, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser261", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P48559", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P48559" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Ser264", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 264, "start_aa": "Ser", "end_pos": 264, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser264", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P48559", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P48559" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Thr13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Tyr157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23427260", "url": "https://glygen.org/publication/PubMed/23427260" }, { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ser159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23427260", "url": "https://glygen.org/publication/PubMed/23427260" }, { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Tyr7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Thr84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005248", "url": "https://www.yeastgenome.org/locus/S000005248" }, { "database": "iPTMnet", "id": "P48559", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48559" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Gly102", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Impairs interaction with MYO2.", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" }, { "database": "PubMed", "id": "12391144", "url": "https://glygen.org/publication/PubMed/12391144" } ] } ] }, { "uniprot_canonical_ac": "P48559-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ile206", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "N", "comment": "Abolishes interaction with MYO2.", "evidence": [ { "database": "UniProtKB", "id": "P48559", "url": "https://www.uniprot.org/uniprotkb/P48559" }, { "database": "PubMed", "id": "12391144", "url": "https://glygen.org/publication/PubMed/12391144" } ] } ] } ], "record_id": "P48559-1" }, { "uniprot_canonical_ac": "P48561-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 642, "chemical_mass": 74179.0, "gene_names": "TRF5;N0440;TRF5", "protein_name": "Poly(A) RNA polymerase protein 1", "disease": [], "biological_process": [ { "name": "nuclear polyadenylation-dependent mRNA catabolic process", "id": "GO:0071042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071042", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "histone mRNA catabolic process", "id": "GO:0071044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071044", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "poly(A)-dependent snoRNA 3'-end processing", "id": "GO:0071051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071051", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snoRNA catabolic process", "id": "GO:0071036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071036", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snRNA catabolic process", "id": "GO:0071037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071037", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent CUT catabolic process", "id": "GO:0071039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071039", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "polyadenylation-dependent ncRNA catabolic process", "id": "GO:0043634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043634", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "RNA fragment catabolic process", "id": "GO:0000292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000292", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "poly(A) RNA polymerase activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" }, { "name": "TRAMP complex", "id": "GO:0031499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031499", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48561-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005243", "url": "https://www.yeastgenome.org/locus/S000005243" }, { "database": "iPTMnet", "id": "P48561", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48561" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P48561-1", "start_pos": "557", "end_pos": "557", "site_lbl": "Ser557", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005243", "url": "https://www.yeastgenome.org/locus/S000005243" }, { "database": "iPTMnet", "id": "P48561", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48561" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48561-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Ser596", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P48561", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48561" } ] } ] }, { "uniprot_canonical_ac": "P48561-1", "start_pos": "602", "end_pos": "602", "site_lbl": "Ser602", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48561", "url": "https://www.uniprot.org/uniprotkb/P48561" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P48561", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48561" } ] } ] }, { "uniprot_canonical_ac": "P48561-1", "start_pos": "611", "end_pos": "611", "site_lbl": "Thr611", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005243", "url": "https://www.yeastgenome.org/locus/S000005243" }, { "database": "iPTMnet", "id": "P48561", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48561" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48561-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Ser613", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005243", "url": "https://www.yeastgenome.org/locus/S000005243" }, { "database": "iPTMnet", "id": "P48561", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48561" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48561-1", "start_pos": "619", "end_pos": "619", "site_lbl": "Ser619", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005243", "url": "https://www.yeastgenome.org/locus/S000005243" }, { "database": "iPTMnet", "id": "P48561", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48561" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48561-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005243", "url": "https://www.yeastgenome.org/locus/S000005243" }, { "database": "iPTMnet", "id": "P48561", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48561" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P48561-1" }, { "uniprot_canonical_ac": "P48563-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1636, "chemical_mass": 186836.0, "gene_names": "MON2;MON2;N0453;YSL2", "protein_name": "Protein MON2", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" }, { "name": "trans-Golgi network membrane organization", "id": "GO:0098629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098629", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48563-1", "start_pos": "1231", "end_pos": "1231", "site_lbl": "Ser1231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Thr32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Ser398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Ser564", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "565", "end_pos": "565", "site_lbl": "Thr565", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "566", "end_pos": "566", "site_lbl": "Ser566", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "567", "end_pos": "567", "site_lbl": "Ser567", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Thr569", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Thr570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "571", "end_pos": "571", "site_lbl": "Ser571", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48563", "url": "https://www.uniprot.org/uniprotkb/P48563" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Ser575", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "582", "end_pos": "582", "site_lbl": "Ser582", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Ser586", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48563-1", "start_pos": "910", "end_pos": "910", "site_lbl": "Ser910", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005241", "url": "https://www.yeastgenome.org/locus/S000005241" }, { "database": "iPTMnet", "id": "P48563", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48563" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P48563-1" }, { "uniprot_canonical_ac": "P48566-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 633, "chemical_mass": 72999.0, "gene_names": "MSB3;GYP3;MSB3;N0470", "protein_name": "GTPase-activating protein GYP3", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:3369", "name": "Ewing sarcoma", "description": "A connective tissue cancer that has_material_basis_in neural crest cells derives_from undeveloped, undifferentiated neuroectoderm.", "url": "https://disease-ontology.org/term/DOID:3369", "evidence": [ { "id": "3369", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3369" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "polarisome", "id": "GO:0000133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000133", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "vesicle targeting", "id": "GO:0006903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006903", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "establishment or maintenance of actin cytoskeleton polarity", "id": "GO:0030950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030950", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" }, { "name": "formin-nucleated actin cable assembly", "id": "GO:0070649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070649", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48566-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ser484", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Ser488", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "499", "end_pos": "499", "site_lbl": "Ser499", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "562", "end_pos": "562", "site_lbl": "Thr562", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Ser570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "572", "end_pos": "572", "site_lbl": "Ser572", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005237", "url": "https://www.yeastgenome.org/locus/S000005237" }, { "database": "iPTMnet", "id": "P48566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48566-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Arg282", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "F", "comment": "Reduced GAP activity.", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" }, { "database": "PubMed", "id": "12913108", "url": "https://glygen.org/publication/PubMed/12913108" } ] }, { "sequence_org": "R", "sequence_mut": "K", "comment": "Reduced GAP activity.", "evidence": [ { "database": "UniProtKB", "id": "P48566", "url": "https://www.uniprot.org/uniprotkb/P48566" }, { "database": "PubMed", "id": "12913108", "url": "https://glygen.org/publication/PubMed/12913108" } ] } ] } ], "record_id": "P48566-1" }, { "uniprot_canonical_ac": "P48581-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 401, "chemical_mass": 45580.0, "gene_names": "RAD17;RAD17", "protein_name": "DNA damage checkpoint control protein RAD17", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "pmid": "" }, { "name": "checkpoint clamp complex", "id": "GO:0030896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030896", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "pmid": "" }, { "name": "nuclease activity", "id": "GO:0004518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004518", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P48581-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005895", "url": "https://www.yeastgenome.org/locus/S000005895" }, { "database": "iPTMnet", "id": "P48581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48581" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48581-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Ser338", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005895", "url": "https://www.yeastgenome.org/locus/S000005895" }, { "database": "iPTMnet", "id": "P48581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48581" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48581-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Thr356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48581" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P48581-1", "start_pos": "357", "end_pos": "357", "site_lbl": "Ser357", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P48581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48581" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P48581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48581" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005895", "url": "https://www.yeastgenome.org/locus/S000005895" }, { "database": "iPTMnet", "id": "P48581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48581" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48581-1", "start_pos": "373", "end_pos": "373", "site_lbl": "Ser373", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005895", "url": "https://www.yeastgenome.org/locus/S000005895" }, { "database": "iPTMnet", "id": "P48581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48581" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48581-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Ser383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P48581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48581" }, { "database": "SGD", "id": "S000005895", "url": "https://www.yeastgenome.org/locus/S000005895" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48581-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P48581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48581" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005895", "url": "https://www.yeastgenome.org/locus/S000005895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P48581-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Glu128", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "In RAD17-1; UV-sensitive.", "evidence": [ { "database": "UniProtKB", "id": "P48581", "url": "https://www.uniprot.org/uniprotkb/P48581" }, { "database": "PubMed", "id": "8649984", "url": "https://glygen.org/publication/PubMed/8649984" } ] } ] } ], "record_id": "P48581-1" }, { "uniprot_canonical_ac": "P49017-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49017", "url": "https://www.uniprot.org/uniprotkb/P49017" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 307, "chemical_mass": 34685.0, "gene_names": "COQ5;COQ5;DBI56;YM8339.09C", "protein_name": "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial", "disease": [ { "disease_id": "DOID:0050730", "name": "coenzyme Q10 deficiency disease", "description": "A mitochondrial metabolism disease that is characterized by a deficiency of CoQ10 resulting from reduced biosynthesis.", "url": "https://disease-ontology.org/term/DOID:0050730", "evidence": [ { "id": "0050730", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050730" } ], "weight": 0.0 }, { "disease_id": "DOID:0112138", "name": "primary coenzyme Q10 deficiency 9", "description": "A coenzyme Q10 deficiency disease characterized by onset in the first decade of life of cerebellar ataxia associated with cerebellar atrophy that has_material_basis_in mutation homozygous or compound heterozygous in the COQ5 gene on chromosome 12q24.31.", "url": "https://disease-ontology.org/term/DOID:0112138", "evidence": [ { "id": "0112138", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112138" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "P49017", "url": "https://www.uniprot.org/uniprotkb/P49017" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P49017", "url": "https://www.uniprot.org/uniprotkb/P49017" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P49017", "url": "https://www.uniprot.org/uniprotkb/P49017" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P49017", "url": "https://www.uniprot.org/uniprotkb/P49017" } ], "pmid": "" } ], "biological_process": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "P49017", "url": "https://www.uniprot.org/uniprotkb/P49017" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "P49017", "url": "https://www.uniprot.org/uniprotkb/P49017" } ], "pmid": "" }, { "name": "aerobic respiration", "id": "GO:0009060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009060", "evidence": [ { "database": "UniProtKB", "id": "P49017", "url": "https://www.uniprot.org/uniprotkb/P49017" } ], "pmid": "" } ], "molecular_function": [ { "name": "2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity", "id": "GO:0008425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008425", "evidence": [ { "database": "UniProtKB", "id": "P49017", "url": "https://www.uniprot.org/uniprotkb/P49017" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49017-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004578", "url": "https://www.yeastgenome.org/locus/S000004578" }, { "database": "iPTMnet", "id": "P49017", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49017" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49017-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004578", "url": "https://www.yeastgenome.org/locus/S000004578" }, { "database": "iPTMnet", "id": "P49017", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49017" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49017-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004578", "url": "https://www.yeastgenome.org/locus/S000004578" }, { "database": "iPTMnet", "id": "P49017", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49017" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49017-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004578", "url": "https://www.yeastgenome.org/locus/S000004578" }, { "database": "iPTMnet", "id": "P49017", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49017" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P49017-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Thr62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004578", "url": "https://www.yeastgenome.org/locus/S000004578" }, { "database": "iPTMnet", "id": "P49017", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49017" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] } ], "record_id": "P49017-1" }, { "uniprot_canonical_ac": "P49018-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 411, "chemical_mass": 47402.0, "gene_names": "GPI8;D9798.2;GPI8", "protein_name": "GPI-anchor transamidase", "disease": [], "molecular_function": [ { "name": "GPI-anchor transamidase activity", "id": "GO:0003923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003923", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" } ], "pmid": "" }, { "name": "GPI-anchor transamidase complex", "id": "GO:0042765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042765", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" } ], "pmid": "" }, { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" } ], "pmid": "" }, { "name": "attachment of GPI anchor to protein", "id": "GO:0016255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016255", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49018-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Asn256", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 256, "start_aa": "Asn", "end_pos": 256, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn256", "evidence": [ { "id": "P49018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49018#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P49018-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Asn346", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 346, "start_aa": "Asn", "end_pos": 346, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn346", "evidence": [ { "id": "P49018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49018#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P49018-1", "start_pos": "157", "end_pos": "157", "site_lbl": "His157", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" }, { "database": "PubMed", "id": "10727241", "url": "https://glygen.org/publication/PubMed/10727241" }, { "database": "PubMed", "id": "10793132", "url": "https://glygen.org/publication/PubMed/10793132" } ] } ] }, { "uniprot_canonical_ac": "P49018-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Cys199", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" }, { "database": "PubMed", "id": "10727241", "url": "https://glygen.org/publication/PubMed/10727241" }, { "database": "PubMed", "id": "10793132", "url": "https://glygen.org/publication/PubMed/10793132" } ] } ] }, { "uniprot_canonical_ac": "P49018-1", "start_pos": "54", "end_pos": "54", "site_lbl": "His54", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Partial loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" }, { "database": "PubMed", "id": "10727241", "url": "https://glygen.org/publication/PubMed/10727241" } ] } ] }, { "uniprot_canonical_ac": "P49018-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" }, { "database": "PubMed", "id": "10727241", "url": "https://glygen.org/publication/PubMed/10727241" } ] }, { "sequence_org": "S", "sequence_mut": "C", "comment": "No loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" }, { "database": "PubMed", "id": "10727241", "url": "https://glygen.org/publication/PubMed/10727241" } ] } ] }, { "uniprot_canonical_ac": "P49018-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Cys85", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "No loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P49018", "url": "https://www.uniprot.org/uniprotkb/P49018" }, { "database": "PubMed", "id": "10727241", "url": "https://glygen.org/publication/PubMed/10727241" } ] } ] } ], "record_id": "P49018-1" }, { "uniprot_canonical_ac": "P49095-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49095", "url": "https://www.uniprot.org/uniprotkb/P49095" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1034, "chemical_mass": 114451.0, "gene_names": "GCV2;GCV2;GSD2;YM9646.01", "protein_name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "disease": [ { "disease_id": "DOID:0070616", "name": "glycine encephalopathy 1", "description": "A glycine encephalopathy that has_material_basis_in homozygous or compound heterozygous mutation in the GLDC gene, a member of the mitochondrial glycine cleavage system that encodes the P protein, on chromosome 9p24.", "url": "https://disease-ontology.org/term/DOID:0070616", "evidence": [ { "id": "0070616", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070616" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:9268", "name": "glycine encephalopathy", "description": "An amino acid metabolic disorder that involves abnormally high levels of the amino acid glycine in bodily fluids and tissues.", "url": "https://disease-ontology.org/term/DOID:9268", "evidence": [ { "id": "9268", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9268" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P49095", "url": "https://www.uniprot.org/uniprotkb/P49095" } ], "pmid": "" }, { "name": "glycine cleavage complex", "id": "GO:0005960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005960", "evidence": [ { "database": "UniProtKB", "id": "P49095", "url": "https://www.uniprot.org/uniprotkb/P49095" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "P49095", "url": "https://www.uniprot.org/uniprotkb/P49095" } ], "pmid": "" }, { "name": "glycine dehydrogenase (decarboxylating) activity", "id": "GO:0004375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004375", "evidence": [ { "database": "UniProtKB", "id": "P49095", "url": "https://www.uniprot.org/uniprotkb/P49095" } ], "pmid": "" }, { "name": "glycine binding", "id": "GO:0016594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016594", "evidence": [ { "database": "UniProtKB", "id": "P49095", "url": "https://www.uniprot.org/uniprotkb/P49095" } ], "pmid": "" } ], "biological_process": [ { "name": "one-carbon metabolic process", "id": "GO:0006730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730", "evidence": [ { "database": "UniProtKB", "id": "P49095", "url": "https://www.uniprot.org/uniprotkb/P49095" } ], "pmid": "" }, { "name": "glycine decarboxylation via glycine cleavage system", "id": "GO:0019464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019464", "evidence": [ { "database": "UniProtKB", "id": "P49095", "url": "https://www.uniprot.org/uniprotkb/P49095" } ], "pmid": "" }, { "name": "glycine catabolic process", "id": "GO:0006546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006546", "evidence": [ { "database": "UniProtKB", "id": "P49095", "url": "https://www.uniprot.org/uniprotkb/P49095" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49095-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004801", "url": "https://www.yeastgenome.org/locus/S000004801" }, { "database": "iPTMnet", "id": "P49095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49095" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P49095-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004801", "url": "https://www.yeastgenome.org/locus/S000004801" }, { "database": "iPTMnet", "id": "P49095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49095" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49095-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004801", "url": "https://www.yeastgenome.org/locus/S000004801" }, { "database": "iPTMnet", "id": "P49095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49095" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49095-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Tyr49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004801", "url": "https://www.yeastgenome.org/locus/S000004801" }, { "database": "iPTMnet", "id": "P49095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49095" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49095-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004801", "url": "https://www.yeastgenome.org/locus/S000004801" }, { "database": "iPTMnet", "id": "P49095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49095" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49095-1", "start_pos": "708", "end_pos": "708", "site_lbl": "Ser708", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49095" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P49095-1", "start_pos": "776", "end_pos": "776", "site_lbl": "Ser776", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004801", "url": "https://www.yeastgenome.org/locus/S000004801" }, { "database": "iPTMnet", "id": "P49095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49095" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P49095-1" }, { "uniprot_canonical_ac": "P49367-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49367", "url": "https://www.uniprot.org/uniprotkb/P49367" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 693, "chemical_mass": 75151.0, "gene_names": "LYS4;LYS3;LYS4;YD8419.01;YD9934.18", "protein_name": "Homoaconitase, mitochondrial", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P49367", "url": "https://www.uniprot.org/uniprotkb/P49367" } ], "pmid": "" } ], "biological_process": [ { "name": "lysine biosynthetic process via aminoadipic acid", "id": "GO:0019878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019878", "evidence": [ { "database": "UniProtKB", "id": "P49367", "url": "https://www.uniprot.org/uniprotkb/P49367" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P49367", "url": "https://www.uniprot.org/uniprotkb/P49367" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "P49367", "url": "https://www.uniprot.org/uniprotkb/P49367" } ], "pmid": "" }, { "name": "homoaconitate hydratase activity", "id": "GO:0004409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004409", "evidence": [ { "database": "UniProtKB", "id": "P49367", "url": "https://www.uniprot.org/uniprotkb/P49367" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49367-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002642", "url": "https://www.yeastgenome.org/locus/S000002642" }, { "database": "iPTMnet", "id": "P49367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P49367-1" }, { "uniprot_canonical_ac": "P49435-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 187, "chemical_mass": 20587.0, "gene_names": "APT1;APT1", "protein_name": "Adenine phosphoribosyltransferase 1", "disease": [ { "disease_id": "DOID:0060350", "name": "adenine phosphoribosyltransferase deficiency", "description": "A purine-pyrimidine metaobolic disorder characterized by the formation 2,8-dihydroxyadenine stones and renal failure secondary to intratubular crystalline precipitation and has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding adenine phosphoribosyltransferase (APRT) on chromosome 16q24.", "url": "https://disease-ontology.org/term/DOID:0060350", "evidence": [ { "id": "0060350", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060350" } ], "weight": 0.0 }, { "disease_id": "DOID:1919", "name": "Lesch-Nyhan syndrome", "description": "A purine-pyrimidine metabolic disorder characterized by mental retardation, spastic cerebral palsy, choreoathetosis, uric acid urinary stones, and self-destructive biting of fingers and lips that has_material_basis_in mutation in the HPRT1 gene on chromosome Xq26.", "url": "https://disease-ontology.org/term/DOID:1919", "evidence": [ { "id": "1919", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1919" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" } ], "pmid": "" }, { "name": "AMP binding", "id": "GO:0016208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016208", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" } ], "pmid": "" }, { "name": "adenine binding", "id": "GO:0002055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002055", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" } ], "pmid": "" }, { "name": "adenine phosphoribosyltransferase activity", "id": "GO:0003999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003999", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" } ], "pmid": "" } ], "biological_process": [ { "name": "AMP salvage", "id": "GO:0044209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044209", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" } ], "pmid": "" }, { "name": "purine ribonucleoside salvage", "id": "GO:0006166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006166", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" } ], "pmid": "" }, { "name": "adenine salvage", "id": "GO:0006168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006168", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49435-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Thr102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004484", "url": "https://www.yeastgenome.org/locus/S000004484" }, { "database": "iPTMnet", "id": "P49435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49435" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004484", "url": "https://www.yeastgenome.org/locus/S000004484" }, { "database": "iPTMnet", "id": "P49435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49435" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Thr176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004484", "url": "https://www.yeastgenome.org/locus/S000004484" }, { "database": "iPTMnet", "id": "P49435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49435" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004484", "url": "https://www.yeastgenome.org/locus/S000004484" }, { "database": "iPTMnet", "id": "P49435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49435" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004484", "url": "https://www.yeastgenome.org/locus/S000004484" }, { "database": "iPTMnet", "id": "P49435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49435" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P49435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49435" }, { "database": "SGD", "id": "S000004484", "url": "https://www.yeastgenome.org/locus/S000004484" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Tyr103", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "4-fold increase in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Glu106", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "L", "comment": "1 million-fold decrease in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] }, { "sequence_org": "E", "sequence_mut": "Q", "comment": "2-fold decrease in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Tyr107", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "D", "comment": "2/3-fold decrease in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] }, { "sequence_org": "Y", "sequence_mut": "F", "comment": "Small decrease in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Gly108", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Small decrease in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] }, { "sequence_org": "G", "sequence_mut": "H", "comment": "2/3-fold decrease in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Arg69", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "4-fold decrease in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Arg89", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "2-fold decrease in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Lys90", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "30-fold decrease in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] } ] }, { "uniprot_canonical_ac": "P49435-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Lys93", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Small increase in activity.", "evidence": [ { "database": "UniProtKB", "id": "P49435", "url": "https://www.uniprot.org/uniprotkb/P49435" }, { "database": "PubMed", "id": "11535055", "url": "https://glygen.org/publication/PubMed/11535055" } ] } ] } ], "record_id": "P49435-1" }, { "uniprot_canonical_ac": "P49573-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 406, "chemical_mass": 44442.0, "gene_names": "CTR1;CTR1;P9642.3", "protein_name": "Copper transport protein CTR1", "disease": [ { "disease_id": "DOID:1838", "name": "Menkes disease", "description": "", "url": "https://disease-ontology.org/term/DOID:1838", "evidence": [ { "id": "1838", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1838" } ], "weight": 0.0 } ], "biological_process": [ { "name": "copper ion transmembrane transport", "id": "GO:0035434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035434", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" } ], "pmid": "" }, { "name": "copper ion import", "id": "GO:0015677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015677", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" } ], "pmid": "" } ], "molecular_function": [ { "name": "copper ion transmembrane transporter activity", "id": "GO:0005375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005375", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49573-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Ser199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Ser303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Thr328", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Thr329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Ser330", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Ser332", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "335", "end_pos": "335", "site_lbl": "Ser335", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Thr336", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Ser349", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Thr356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Thr358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Thr367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P49573", "url": "https://www.uniprot.org/uniprotkb/P49573" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "384", "end_pos": "384", "site_lbl": "Ser384", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49573-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Ser390", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006328", "url": "https://www.yeastgenome.org/locus/S000006328" }, { "database": "iPTMnet", "id": "P49573", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49573" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P49573-1" }, { "uniprot_canonical_ac": "P49626-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 362, "chemical_mass": 39062.0, "gene_names": "RPL4B;RPL2B;RPL4B;YD8119.17", "protein_name": "Large ribosomal subunit protein uL4B", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49626-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Thr122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49626" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49626" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Thr129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49626" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49626" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002419", "url": "https://www.yeastgenome.org/locus/S000002419" }, { "database": "iPTMnet", "id": "P49626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49626" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002419", "url": "https://www.yeastgenome.org/locus/S000002419" }, { "database": "iPTMnet", "id": "P49626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49626" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Thr283", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002419", "url": "https://www.yeastgenome.org/locus/S000002419" }, { "database": "iPTMnet", "id": "P49626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49626" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002419", "url": "https://www.yeastgenome.org/locus/S000002419" }, { "database": "iPTMnet", "id": "P49626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49626" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002419", "url": "https://www.yeastgenome.org/locus/S000002419" }, { "database": "iPTMnet", "id": "P49626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49626" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Ile289", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "A", "comment": "Leads to an inefficient release from ACL4 with a delayed assembly into the 60S subunit; when associated with A-290 and A-295.", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" }, { "database": "PubMed", "id": "25936803", "url": "https://glygen.org/publication/PubMed/25936803" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Ile290", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "A", "comment": "Leads to an inefficient release from ACL4 with a delayed assembly into the 60S subunit; when associated with A-289 and A-295.", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" }, { "database": "PubMed", "id": "25936803", "url": "https://glygen.org/publication/PubMed/25936803" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Ile295", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "A", "comment": "Leads to an inefficient release from ACL4 with a delayed assembly into the 60S subunit; when associated with A-289 and A-290.", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" }, { "database": "PubMed", "id": "25936803", "url": "https://glygen.org/publication/PubMed/25936803" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Lys314", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Significantly diminished nuclear localization; when associated with A-315 and A-319.", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" }, { "database": "PubMed", "id": "25936803", "url": "https://glygen.org/publication/PubMed/25936803" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Lys315", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Significantly diminished nuclear localization; when associated with A-314 and A-319.", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" }, { "database": "PubMed", "id": "25936803", "url": "https://glygen.org/publication/PubMed/25936803" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Lys319", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Significantly diminished nuclear localization; when associated with A-314 and A-315.", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" }, { "database": "PubMed", "id": "25936803", "url": "https://glygen.org/publication/PubMed/25936803" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Lys332", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "Leads to an inefficient release from ACL4 with a delayed assembly into the 60S subunit; when associated with A-334.", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" }, { "database": "PubMed", "id": "25936803", "url": "https://glygen.org/publication/PubMed/25936803" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Phe334", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Leads to an inefficient release from ACL4 with a delayed assembly into the 60S subunit; when associated with e-332.", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" }, { "database": "PubMed", "id": "25936803", "url": "https://glygen.org/publication/PubMed/25936803" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Arg95", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Leads to a slower growth at higher temperatures but allows RPL4 assembly into the 60S subunit; when associated with E-98.", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" }, { "database": "PubMed", "id": "25936803", "url": "https://glygen.org/publication/PubMed/25936803" } ] } ] }, { "uniprot_canonical_ac": "P49626-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Arg98", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Leads to a slower growth at higher temperatures but allows RPL4 assembly into the mature 60S; when associated with E-95.", "evidence": [ { "database": "UniProtKB", "id": "P49626", "url": "https://www.uniprot.org/uniprotkb/P49626" }, { "database": "PubMed", "id": "25936803", "url": "https://glygen.org/publication/PubMed/25936803" } ] } ] } ], "record_id": "P49626-1" }, { "uniprot_canonical_ac": "P49686-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 430, "chemical_mass": 42778.0, "gene_names": "NUP42;NUP42;RIP1;UIP1;YD9346.04C", "protein_name": "Nucleoporin NUP42", "disease": [], "biological_process": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" }, { "name": "mRNA export from nucleus in response to heat stress", "id": "GO:0031990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031990", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" }, { "name": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000973", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" }, { "name": "NLS-bearing protein import into nucleus", "id": "GO:0006607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006607", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" }, { "name": "transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000972", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" }, { "name": "nuclear pore cytoplasmic filaments", "id": "GO:0044614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044614", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" }, { "name": "nuclear pore central transport channel", "id": "GO:0044613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044613", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49686-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 245, "start_aa": "Ser", "end_pos": 245, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser245", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P49686", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P49686" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Ser248", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 248, "start_aa": "Ser", "end_pos": 248, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser248", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P49686", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P49686" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Ser252", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 252, "start_aa": "Ser", "end_pos": 252, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser252", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P49686", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P49686" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Ser258", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 258, "start_aa": "Ser", "end_pos": 258, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser258", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P49686", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P49686" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 259, "start_aa": "Ser", "end_pos": 259, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser259", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P49686", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P49686" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 266, "start_aa": "Ser", "end_pos": 266, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser266", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P49686", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P49686" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P49686", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49686" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002600", "url": "https://www.yeastgenome.org/locus/S000002600" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Ser140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49686", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49686" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Ser286", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002600", "url": "https://www.yeastgenome.org/locus/S000002600" }, { "database": "iPTMnet", "id": "P49686", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49686" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002600", "url": "https://www.yeastgenome.org/locus/S000002600" }, { "database": "iPTMnet", "id": "P49686", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49686" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P49686", "url": "https://www.uniprot.org/uniprotkb/P49686" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P49686", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49686" }, { "database": "SGD", "id": "S000002600", "url": "https://www.yeastgenome.org/locus/S000002600" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49686-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Ser300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002600", "url": "https://www.yeastgenome.org/locus/S000002600" }, { "database": "iPTMnet", "id": "P49686", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49686" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P49686-1" }, { "uniprot_canonical_ac": "P49704-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 494, "chemical_mass": 56303.0, "gene_names": "PRP31;PRP31", "protein_name": "Pre-mRNA-processing factor 31", "disease": [ { "disease_id": "DOID:0110408", "name": "retinitis pigmentosa 11", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the PRPF31 gene on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0110408", "evidence": [ { "id": "0110408", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110408" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "pmid": "" }, { "name": "U4 snRNP", "id": "GO:0005687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005687", "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "pmid": "" }, { "name": "spliceosomal tri-snRNP complex", "id": "GO:0097526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097526", "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "pmid": "" } ], "biological_process": [ { "name": "spliceosomal tri-snRNP complex assembly", "id": "GO:0000244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000244", "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "pmid": "" }, { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P49704", "url": "https://www.uniprot.org/uniprotkb/P49704" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49704-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003323", "url": "https://www.yeastgenome.org/locus/S000003323" }, { "database": "iPTMnet", "id": "P49704", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49704" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49704-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003323", "url": "https://www.yeastgenome.org/locus/S000003323" }, { "database": "iPTMnet", "id": "P49704", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49704" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49704-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Ser469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003323", "url": "https://www.yeastgenome.org/locus/S000003323" }, { "database": "iPTMnet", "id": "P49704", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49704" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49704-1", "start_pos": "491", "end_pos": "491", "site_lbl": "Ser491", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003323", "url": "https://www.yeastgenome.org/locus/S000003323" }, { "database": "iPTMnet", "id": "P49704", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49704" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P49704-1" }, { "uniprot_canonical_ac": "P49775-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 206, "chemical_mass": 23542.0, "gene_names": "HNT2;APH1;D9740.15;HNT2", "protein_name": "Bis(5'-adenosyl)-triphosphatase", "disease": [ { "disease_id": "DOID:0050465", "name": "Muir-Torre syndrome", "description": "A Lynch syndrome that is characterized by a propensity to develop cancers of the gastrointestinal tract, genitourinary tract, and skin that has_material_basis_in mutations in DNA mismatch repair genes.", "url": "https://disease-ontology.org/term/DOID:0050465", "evidence": [ { "id": "0050465", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050465" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1749", "name": "squamous cell carcinoma", "description": "A carcinoma that derives_from squamous epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1749", "evidence": [ { "id": "1749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1749" } ], "weight": 0.0 }, { "disease_id": "DOID:2999", "name": "granulosa cell tumor", "description": "A sex cord-gonadal stromal tumor that has_material_basis_in granulosa cells and arises from the sex cord stroma.", "url": "https://disease-ontology.org/term/DOID:2999", "evidence": [ { "id": "2999", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2999" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4440", "name": "seminoma", "description": "A germinoma that has_material_basis_in cells that make sperm and eggs.", "url": "https://disease-ontology.org/term/DOID:4440", "evidence": [ { "id": "4440", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4440" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" } ], "pmid": "" }, { "name": "bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity", "id": "GO:0004081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004081", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" } ], "pmid": "" }, { "name": "ribonucleoside triphosphate phosphatase activity", "id": "GO:0017111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017111", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" } ], "pmid": "" }, { "name": "bis(5'-adenosyl)-triphosphatase activity", "id": "GO:0047710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047710", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleoside catabolic process", "id": "GO:0009164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009164", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49775-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002713", "url": "https://www.yeastgenome.org/locus/S000002713" }, { "database": "iPTMnet", "id": "P49775", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49775" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49775-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Thr179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002713", "url": "https://www.yeastgenome.org/locus/S000002713" }, { "database": "iPTMnet", "id": "P49775", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49775" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49775-1", "start_pos": "98", "end_pos": "98", "site_lbl": "His98", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Fails to reduce intracellular dinucleoside polyphosphate levels.", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" }, { "database": "PubMed", "id": "12028594", "url": "https://glygen.org/publication/PubMed/12028594" } ] }, { "sequence_org": "H", "sequence_mut": "D", "comment": "Fails to reduce intracellular dinucleoside polyphosphate levels.", "evidence": [ { "database": "UniProtKB", "id": "P49775", "url": "https://www.uniprot.org/uniprotkb/P49775" }, { "database": "PubMed", "id": "12028594", "url": "https://glygen.org/publication/PubMed/12028594" } ] } ] } ], "record_id": "P49775-1" }, { "uniprot_canonical_ac": "P49955-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49955", "url": "https://www.uniprot.org/uniprotkb/P49955" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 971, "chemical_mass": 110028.0, "gene_names": "HSH155;HSH155;YM8021.14", "protein_name": "U2 snRNP component HSH155", "disease": [ { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0050939", "name": "uterine corpus endometrial carcinoma", "description": "A uterine corpus cancer that is derives_from the inner lining of the uterus.", "url": "https://disease-ontology.org/term/DOID:0050939", "evidence": [ { "id": "0050939", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050939" } ], "weight": 0.0 }, { "disease_id": "DOID:4006", "name": "bladder urothelial carcinoma", "description": "A bladder carcinoma that has_material_basis_in transitional cells located_in the lining of the bladder.", "url": "https://disease-ontology.org/term/DOID:4006", "evidence": [ { "id": "4006", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4006" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P49955", "url": "https://www.uniprot.org/uniprotkb/P49955" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P49955", "url": "https://www.uniprot.org/uniprotkb/P49955" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "P49955", "url": "https://www.uniprot.org/uniprotkb/P49955" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "P49955", "url": "https://www.uniprot.org/uniprotkb/P49955" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "P49955", "url": "https://www.uniprot.org/uniprotkb/P49955" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P49955", "url": "https://www.uniprot.org/uniprotkb/P49955" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "P49955", "url": "https://www.uniprot.org/uniprotkb/P49955" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "P49955", "url": "https://www.uniprot.org/uniprotkb/P49955" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49955-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Thr503", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49955" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P49955-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Tyr504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49955" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P49955-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Thr506", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49955" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P49955-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004901", "url": "https://www.yeastgenome.org/locus/S000004901" }, { "database": "iPTMnet", "id": "P49955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49955" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49955-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Thr83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004901", "url": "https://www.yeastgenome.org/locus/S000004901" }, { "database": "iPTMnet", "id": "P49955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49955" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49955-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004901", "url": "https://www.yeastgenome.org/locus/S000004901" }, { "database": "iPTMnet", "id": "P49955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49955" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49955-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Thr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004901", "url": "https://www.yeastgenome.org/locus/S000004901" }, { "database": "iPTMnet", "id": "P49955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49955" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] } ], "record_id": "P49955-1" }, { "uniprot_canonical_ac": "P49956-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 741, "chemical_mass": 84373.0, "gene_names": "CTF18;CHL12;CTF18;YM9582.03C", "protein_name": "Chromosome transmission fidelity protein 18", "disease": [], "cellular_component": [ { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" }, { "name": "Ctf18 RFC-like complex", "id": "GO:0031390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031390", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" } ], "biological_process": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" }, { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" }, { "name": "telomere tethering at nuclear periphery", "id": "GO:0034398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034398", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" }, { "name": "maintenance of DNA trinucleotide repeats", "id": "GO:0035753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035753", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49956-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Ser321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "525", "end_pos": "525", "site_lbl": "Ser525", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "532", "end_pos": "532", "site_lbl": "Ser532", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "653", "end_pos": "653", "site_lbl": "Thr653", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "659", "end_pos": "659", "site_lbl": "Ser659", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "669", "end_pos": "669", "site_lbl": "Thr669", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "674", "end_pos": "674", "site_lbl": "Ser674", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "675", "end_pos": "675", "site_lbl": "Ser675", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "676", "end_pos": "676", "site_lbl": "Ser676", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "677", "end_pos": "677", "site_lbl": "Thr677", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "691", "end_pos": "691", "site_lbl": "Thr691", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "700", "end_pos": "700", "site_lbl": "Thr700", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "703", "end_pos": "703", "site_lbl": "Ser703", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "706", "end_pos": "706", "site_lbl": "Thr706", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Thr715", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004683", "url": "https://www.yeastgenome.org/locus/S000004683" }, { "database": "iPTMnet", "id": "P49956", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49956-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Lys189", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "Fails to unload PCNA.", "evidence": [ { "database": "UniProtKB", "id": "P49956", "url": "https://www.uniprot.org/uniprotkb/P49956" }, { "database": "PubMed", "id": "15964801", "url": "https://glygen.org/publication/PubMed/15964801" } ] } ] } ], "record_id": "P49956-1" }, { "uniprot_canonical_ac": "P49957-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 279, "chemical_mass": 32439.0, "gene_names": "TRM9;KTI1;TRM9;YM9571.04", "protein_name": "tRNA (carboxymethyluridine(34)-5-O)-methyltransferase", "disease": [ { "disease_id": "DOID:0081232", "name": "autosomal recessive intellectual developmental disorder 71", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the ALKBH8 gene on chromosome 11q22.", "url": "https://disease-ontology.org/term/DOID:0081232", "evidence": [ { "id": "0081232", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081232" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "tRNA methyltransferase activity", "id": "GO:0008175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008175", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" }, { "name": "tRNA (uridine) methyltransferase activity", "id": "GO:0016300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016300", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" }, { "name": "tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity", "id": "GO:0106335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106335", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" }, { "name": "regulation of translational elongation", "id": "GO:0006448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006448", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" }, { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "P49957", "url": "https://www.uniprot.org/uniprotkb/P49957" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49957-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Thr182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004476", "url": "https://www.yeastgenome.org/locus/S000004476" }, { "database": "iPTMnet", "id": "P49957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49957" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P49957-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P49957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49957" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004476", "url": "https://www.yeastgenome.org/locus/S000004476" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49957-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004476", "url": "https://www.yeastgenome.org/locus/S000004476" }, { "database": "iPTMnet", "id": "P49957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49957" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49957-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004476", "url": "https://www.yeastgenome.org/locus/S000004476" }, { "database": "iPTMnet", "id": "P49957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49957" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P49957-1" }, { "uniprot_canonical_ac": "P49960-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 444, "chemical_mass": 50849.0, "gene_names": "PRP24;PRP24;YM8156.10C", "protein_name": "U4/U6 snRNA-associated-splicing factor PRP24", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" } ], "pmid": "" }, { "name": "snRNA binding", "id": "GO:0017069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017069", "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" } ], "pmid": "" }, { "name": "U6 snRNA binding", "id": "GO:0017070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017070", "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" } ], "pmid": "" }, { "name": "U6 snRNP", "id": "GO:0005688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005688", "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" } ], "pmid": "" } ], "biological_process": [ { "name": "spliceosomal tri-snRNP complex assembly", "id": "GO:0000244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000244", "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P49960-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004881", "url": "https://www.yeastgenome.org/locus/S000004881" }, { "database": "iPTMnet", "id": "P49960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49960" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49960-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P49960", "url": "https://www.uniprot.org/uniprotkb/P49960" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P49960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49960" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004881", "url": "https://www.yeastgenome.org/locus/S000004881" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49960-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004881", "url": "https://www.yeastgenome.org/locus/S000004881" }, { "database": "iPTMnet", "id": "P49960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49960" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P49960-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004881", "url": "https://www.yeastgenome.org/locus/S000004881" }, { "database": "iPTMnet", "id": "P49960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49960" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P49960-1" }, { "uniprot_canonical_ac": "P50079-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 448, "chemical_mass": 51235.0, "gene_names": "HSV2;G8530;HSV2", "protein_name": "SVP1-like protein 2", "disease": [ { "disease_id": "DOID:0110739", "name": "neurodegeneration with brain iron accumulation 5", "description": "A neurodegeneration with brain iron accumulation that has_material_basis_in X-linked dominant inheritance of mutation in the WDR45 gene on chromosome Xp11.23.", "url": "https://disease-ontology.org/term/DOID:0110739", "evidence": [ { "id": "0110739", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110739" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phosphatidylinositol-5-phosphate binding", "id": "GO:0010314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010314", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" } ], "biological_process": [ { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "glycophagy", "id": "GO:0061723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061723", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "P50079", "url": "https://www.uniprot.org/uniprotkb/P50079" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50079-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Asn155", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 155, "start_aa": "Asn", "end_pos": 155, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn155", "evidence": [ { "id": "P50079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50079#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P50079-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Asn256", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 256, "start_aa": "Asn", "end_pos": 256, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn256", "evidence": [ { "id": "P50079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50079#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P50079-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Asn280", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 280, "start_aa": "Asn", "end_pos": 280, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn280", "evidence": [ { "id": "P50079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50079#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P50079-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Asn315", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 315, "start_aa": "Asn", "end_pos": 315, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn315", "evidence": [ { "id": "P50079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50079#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P50079-1", "start_pos": "421", "end_pos": "421", "site_lbl": "Asn421", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 421, "start_aa": "Asn", "end_pos": 421, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn421", "evidence": [ { "id": "P50079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50079#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P50079-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Asn61", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 61, "start_aa": "Asn", "end_pos": 61, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn61", "evidence": [ { "id": "P50079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50079#ptm_processing" } ] } ] } ], "record_id": "P50079-1" }, { "uniprot_canonical_ac": "P50082-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 593, "chemical_mass": 67027.0, "gene_names": "AMA1;AMA1;G8541;SPO70", "protein_name": "Meiosis-specific APC/C activator protein AMA1", "disease": [], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "synaptonemal complex assembly", "id": "GO:0007130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007130", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "regulation of meiotic cell cycle", "id": "GO:0051445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051445", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "meiotic chromosome segregation", "id": "GO:0045132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045132", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "meiosis I", "id": "GO:0007127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007127", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "meiotic DNA integrity checkpoint signaling", "id": "GO:0044778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044778", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "positive regulation of anaphase-promoting complex-dependent catabolic process", "id": "GO:1905786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905786", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "positive regulation of ascospore-type prospore membrane formation", "id": "GO:1903024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903024", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "ascospore formation", "id": "GO:0030437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030437", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "ascospore wall assembly", "id": "GO:0030476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030476", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" } ], "cellular_component": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" } ], "molecular_function": [ { "name": "anaphase-promoting complex binding", "id": "GO:0010997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010997", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" }, { "name": "ubiquitin ligase activator activity", "id": "GO:1990757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990757", "evidence": [ { "database": "UniProtKB", "id": "P50082", "url": "https://www.uniprot.org/uniprotkb/P50082" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P50082-1" }, { "uniprot_canonical_ac": "P50085-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50085", "url": "https://www.uniprot.org/uniprotkb/P50085" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 310, "chemical_mass": 34407.0, "gene_names": "PHB2;G8561;PHB2", "protein_name": "Prohibitin-2", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P50085", "url": "https://www.uniprot.org/uniprotkb/P50085" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P50085", "url": "https://www.uniprot.org/uniprotkb/P50085" } ], "pmid": "" } ], "biological_process": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "P50085", "url": "https://www.uniprot.org/uniprotkb/P50085" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P50085", "url": "https://www.uniprot.org/uniprotkb/P50085" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "P50085", "url": "https://www.uniprot.org/uniprotkb/P50085" } ], "pmid": "" }, { "name": "negative regulation of proteolysis", "id": "GO:0045861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045861", "evidence": [ { "database": "UniProtKB", "id": "P50085", "url": "https://www.uniprot.org/uniprotkb/P50085" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "P50085", "url": "https://www.uniprot.org/uniprotkb/P50085" } ], "pmid": "" }, { "name": "substrate localization to autophagosome", "id": "GO:0061753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061753", "evidence": [ { "database": "UniProtKB", "id": "P50085", "url": "https://www.uniprot.org/uniprotkb/P50085" } ], "pmid": "" }, { "name": "mitochondrion inheritance", "id": "GO:0000001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000001", "evidence": [ { "database": "UniProtKB", "id": "P50085", "url": "https://www.uniprot.org/uniprotkb/P50085" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P50085-1" }, { "uniprot_canonical_ac": "P50087-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50087", "url": "https://www.uniprot.org/uniprotkb/P50087" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 233, "chemical_mass": 26912.0, "gene_names": "MIC26;G8575;MCS29;MIC26;MIO27;MOS2", "protein_name": "MICOS subunit MIC26", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P50087", "url": "https://www.uniprot.org/uniprotkb/P50087" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P50087", "url": "https://www.uniprot.org/uniprotkb/P50087" } ], "pmid": "" }, { "name": "mitochondrial crista junction", "id": "GO:0044284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044284", "evidence": [ { "database": "UniProtKB", "id": "P50087", "url": "https://www.uniprot.org/uniprotkb/P50087" } ], "pmid": "" }, { "name": "MICOS complex", "id": "GO:0061617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061617", "evidence": [ { "database": "UniProtKB", "id": "P50087", "url": "https://www.uniprot.org/uniprotkb/P50087" } ], "pmid": "" } ], "biological_process": [ { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "P50087", "url": "https://www.uniprot.org/uniprotkb/P50087" } ], "pmid": "" }, { "name": "negative regulation of protein oligomerization", "id": "GO:0032460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032460", "evidence": [ { "database": "UniProtKB", "id": "P50087", "url": "https://www.uniprot.org/uniprotkb/P50087" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50087-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50087", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50087" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P50087-1" }, { "uniprot_canonical_ac": "P50090-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 882, "chemical_mass": 99975.0, "gene_names": "KEL2;G8585;KEL2", "protein_name": "Kelch repeat-containing protein 2", "disease": [ { "disease_id": "DOID:0111814", "name": "methylmalonic acidemia and homocysteinemia cblX type", "description": "A methylmalonic acidemia characterized by onset in infancy of severely delayed psychomotor development, failure to thrive, intellectual disability, and intractable epilepsy that has_material_basis_in hemizygous or homozygous mutation in the HCFC1 gene on chromosome Xq28.", "url": "https://disease-ontology.org/term/DOID:0111814", "evidence": [ { "id": "0111814", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111814" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "regulation of vesicle-mediated transport", "id": "GO:0060627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060627", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "negative regulation of exit from mitosis", "id": "GO:0001100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001100", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "conjugation with cellular fusion", "id": "GO:0000747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000747", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "regulation of formin-nucleated actin cable assembly", "id": "GO:0090337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090337", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "establishment or maintenance of bipolar cell polarity", "id": "GO:0061245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061245", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" } ], "cellular_component": [ { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "cell cortex of cell tip", "id": "GO:0051285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051285", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" }, { "name": "Kelch-containing formin regulatory complex", "id": "GO:1990615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990615", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50090-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Thr41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "428", "end_pos": "428", "site_lbl": "Ser428", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Thr455", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Ser461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "465", "end_pos": "465", "site_lbl": "Ser465", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Ser475", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "478", "end_pos": "478", "site_lbl": "Ser478", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "509", "end_pos": "509", "site_lbl": "Ser509", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P50090", "url": "https://www.uniprot.org/uniprotkb/P50090" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "528", "end_pos": "528", "site_lbl": "Thr528", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Ser531", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Ser62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Ser715", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "760", "end_pos": "760", "site_lbl": "Ser760", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50090-1", "start_pos": "796", "end_pos": "796", "site_lbl": "Ser796", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003470", "url": "https://www.yeastgenome.org/locus/S000003470" }, { "database": "iPTMnet", "id": "P50090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P50090-1" }, { "uniprot_canonical_ac": "P50094-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50094", "url": "https://www.uniprot.org/uniprotkb/P50094" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 524, "chemical_mass": 56394.0, "gene_names": "IMD4;IMD4;YM9958.06C", "protein_name": "Inosine-5'-monophosphate dehydrogenase 4", "disease": [ { "disease_id": "DOID:0110216", "name": "Leber congenital amaurosis 11", "description": "A Leber congenital amaurosis that has_material_basis_in mutation n the IMPDH1 gene on chromosome 7q31.3-q32.", "url": "https://disease-ontology.org/term/DOID:0110216", "evidence": [ { "id": "0110216", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110216" } ], "weight": 0.0 }, { "disease_id": "DOID:0110388", "name": "retinitis pigmentosa 10", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the IMPDH1 gene on chromosome 7q32.", "url": "https://disease-ontology.org/term/DOID:0110388", "evidence": [ { "id": "0110388", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110388" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P50094", "url": "https://www.uniprot.org/uniprotkb/P50094" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P50094", "url": "https://www.uniprot.org/uniprotkb/P50094" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "P50094", "url": "https://www.uniprot.org/uniprotkb/P50094" } ], "pmid": "" }, { "name": "IMP dehydrogenase activity", "id": "GO:0003938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003938", "evidence": [ { "database": "UniProtKB", "id": "P50094", "url": "https://www.uniprot.org/uniprotkb/P50094" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P50094", "url": "https://www.uniprot.org/uniprotkb/P50094" } ], "pmid": "" } ], "biological_process": [ { "name": "GMP biosynthetic process", "id": "GO:0006177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006177", "evidence": [ { "database": "UniProtKB", "id": "P50094", "url": "https://www.uniprot.org/uniprotkb/P50094" } ], "pmid": "" }, { "name": "GTP biosynthetic process", "id": "GO:0006183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006183", "evidence": [ { "database": "UniProtKB", "id": "P50094", "url": "https://www.uniprot.org/uniprotkb/P50094" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50094-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P50094", "url": "https://www.uniprot.org/uniprotkb/P50094" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P50094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50094" }, { "database": "SGD", "id": "S000004520", "url": "https://www.yeastgenome.org/locus/S000004520" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50094-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004520", "url": "https://www.yeastgenome.org/locus/S000004520" }, { "database": "iPTMnet", "id": "P50094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50094-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004520", "url": "https://www.yeastgenome.org/locus/S000004520" }, { "database": "iPTMnet", "id": "P50094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50094-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50094" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004520", "url": "https://www.yeastgenome.org/locus/S000004520" } ] } ] }, { "uniprot_canonical_ac": "P50094-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004520", "url": "https://www.yeastgenome.org/locus/S000004520" }, { "database": "iPTMnet", "id": "P50094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50094-1", "start_pos": "428", "end_pos": "428", "site_lbl": "Thr428", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004520", "url": "https://www.yeastgenome.org/locus/S000004520" }, { "database": "iPTMnet", "id": "P50094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50094" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P50094-1", "start_pos": "476", "end_pos": "476", "site_lbl": "Ser476", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004520", "url": "https://www.yeastgenome.org/locus/S000004520" }, { "database": "iPTMnet", "id": "P50094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P50094-1" }, { "uniprot_canonical_ac": "P50095-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 523, "chemical_mass": 56585.0, "gene_names": "IMD3;IMD3;L9753.4", "protein_name": "Inosine-5'-monophosphate dehydrogenase 3", "disease": [ { "disease_id": "DOID:0110216", "name": "Leber congenital amaurosis 11", "description": "A Leber congenital amaurosis that has_material_basis_in mutation n the IMPDH1 gene on chromosome 7q31.3-q32.", "url": "https://disease-ontology.org/term/DOID:0110216", "evidence": [ { "id": "0110216", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110216" } ], "weight": 0.0 }, { "disease_id": "DOID:0110388", "name": "retinitis pigmentosa 10", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the IMPDH1 gene on chromosome 7q32.", "url": "https://disease-ontology.org/term/DOID:0110388", "evidence": [ { "id": "0110388", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110388" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" } ], "pmid": "" }, { "name": "IMP dehydrogenase activity", "id": "GO:0003938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003938", "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" } ], "pmid": "" } ], "biological_process": [ { "name": "GMP biosynthetic process", "id": "GO:0006177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006177", "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" } ], "pmid": "" }, { "name": "GTP biosynthetic process", "id": "GO:0006183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006183", "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50095-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Thr132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Ser240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Ser504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "516", "end_pos": "516", "site_lbl": "Ser516", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Thr9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004424", "url": "https://www.yeastgenome.org/locus/S000004424" }, { "database": "iPTMnet", "id": "P50095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50095" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50095-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Ala253", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "S", "comment": "Increases drug-resistance to MPA.", "evidence": [ { "database": "UniProtKB", "id": "P50095", "url": "https://www.uniprot.org/uniprotkb/P50095" }, { "database": "PubMed", "id": "16278936", "url": "https://glygen.org/publication/PubMed/16278936" } ] } ] } ], "record_id": "P50095-1" }, { "uniprot_canonical_ac": "P50101-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1230, "chemical_mass": 143564.0, "gene_names": "UBP15;UBP15;YM9952.06", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15", "disease": [], "biological_process": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" }, { "name": "free ubiquitin chain depolymerization", "id": "GO:0010995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010995", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50101-1", "start_pos": "1057", "end_pos": "1057", "site_lbl": "Ser1057", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004920", "url": "https://www.yeastgenome.org/locus/S000004920" }, { "database": "iPTMnet", "id": "P50101", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50101" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50101-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004920", "url": "https://www.yeastgenome.org/locus/S000004920" }, { "database": "iPTMnet", "id": "P50101", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50101" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50101-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Thr238", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004920", "url": "https://www.yeastgenome.org/locus/S000004920" }, { "database": "iPTMnet", "id": "P50101", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50101" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50101-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004920", "url": "https://www.yeastgenome.org/locus/S000004920" }, { "database": "iPTMnet", "id": "P50101", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50101" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50101-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50101", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50101" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P50101-1", "start_pos": "938", "end_pos": "938", "site_lbl": "Ser938", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004920", "url": "https://www.yeastgenome.org/locus/S000004920" }, { "database": "iPTMnet", "id": "P50101", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50101" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50101-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Cys214", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Abolished deubiquitinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P50101", "url": "https://www.uniprot.org/uniprotkb/P50101" }, { "database": "PubMed", "id": "21665945", "url": "https://glygen.org/publication/PubMed/21665945" } ] } ] } ], "record_id": "P50101-1" }, { "uniprot_canonical_ac": "P50102-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 471, "chemical_mass": 53623.0, "gene_names": "UBP8;UBP8;YM9959.05", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 8", "disease": [ { "disease_id": "DOID:0112036", "name": "non-syndromic X-linked intellectual disability 105", "description": "A non-syndromic X-linked intellectual disability characterized by borderline to moderate intellectual disability, variable poor or absent speech, and behavioral problems that has_material_basis_in hemizygous mutation in the USP27X gene on chromosome Xp11.23.", "url": "https://disease-ontology.org/term/DOID:0112036", "evidence": [ { "id": "0112036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112036" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" }, { "name": "DUBm complex", "id": "GO:0071819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071819", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" }, { "name": "SLIK (SAGA-like) complex", "id": "GO:0046695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046695", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50102-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Cys146", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Lowers histone H2B deubiquitination activity.", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" }, { "database": "PubMed", "id": "15657441", "url": "https://glygen.org/publication/PubMed/15657441" } ] } ] }, { "uniprot_canonical_ac": "P50102-1", "start_pos": "419", "end_pos": "419", "site_lbl": "His419", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Lowers histone H2B deubiquitination activity.", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" }, { "database": "PubMed", "id": "15657441", "url": "https://glygen.org/publication/PubMed/15657441" } ] } ] }, { "uniprot_canonical_ac": "P50102-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Cys46", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Lowers histone H2B deubiquitination activity; when associated with A-49.", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" }, { "database": "PubMed", "id": "15657441", "url": "https://glygen.org/publication/PubMed/15657441" } ] } ] }, { "uniprot_canonical_ac": "P50102-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Cys49", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Lowers histone H2B deubiquitination activity; when associated with A-46.", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" }, { "database": "PubMed", "id": "15657441", "url": "https://glygen.org/publication/PubMed/15657441" } ] } ] }, { "uniprot_canonical_ac": "P50102-1", "start_pos": "77", "end_pos": "77", "site_lbl": "His77", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Lowers histone H2B deubiquitination activity.", "evidence": [ { "database": "UniProtKB", "id": "P50102", "url": "https://www.uniprot.org/uniprotkb/P50102" }, { "database": "PubMed", "id": "15657441", "url": "https://glygen.org/publication/PubMed/15657441" } ] } ] } ], "record_id": "P50102-1" }, { "uniprot_canonical_ac": "P50106-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 137, "chemical_mass": 14585.0, "gene_names": "RPA14;RPA14;YD8358.11", "protein_name": "DNA-directed RNA polymerase I subunit RPA14", "disease": [], "biological_process": [ { "name": "transcription by RNA polymerase I", "id": "GO:0006360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006360", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase I", "id": "GO:0006362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006362", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase I promoter", "id": "GO:0006361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006361", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "pmid": "" }, { "name": "termination of RNA polymerase I transcription", "id": "GO:0006363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006363", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "pmid": "" }, { "name": "regulation of cell size", "id": "GO:0008361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008361", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "pmid": "" }, { "name": "nucleolar large rRNA transcription by RNA polymerase I", "id": "GO:0042790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042790", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "pmid": "" }, { "name": "RNA polymerase I complex", "id": "GO:0005736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005736", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50106-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002563", "url": "https://www.yeastgenome.org/locus/S000002563" }, { "database": "iPTMnet", "id": "P50106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50106" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50106-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Thr120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002563", "url": "https://www.yeastgenome.org/locus/S000002563" }, { "database": "iPTMnet", "id": "P50106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50106" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50106-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P50106", "url": "https://www.uniprot.org/uniprotkb/P50106" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P50106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50106" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002563", "url": "https://www.yeastgenome.org/locus/S000002563" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50106-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002563", "url": "https://www.yeastgenome.org/locus/S000002563" }, { "database": "iPTMnet", "id": "P50106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50106" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50106-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Thr127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50106" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P50106-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Thr133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002563", "url": "https://www.yeastgenome.org/locus/S000002563" }, { "database": "iPTMnet", "id": "P50106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50106" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P50106-1" }, { "uniprot_canonical_ac": "P50107-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50107", "url": "https://www.uniprot.org/uniprotkb/P50107" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 326, "chemical_mass": 37209.0, "gene_names": "GLO1;GLO1;YM9571.15C", "protein_name": "Glyoxalase I", "disease": [ { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:178", "name": "vascular disease", "description": "A cardiovascular system disease that primarily affects the blood vessels which includes the arteries, veins and capillaries that carry blood to and from the heart.", "url": "https://disease-ontology.org/term/DOID:178", "evidence": [ { "id": "178", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:178" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "id": "GO:0019243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019243", "evidence": [ { "database": "UniProtKB", "id": "P50107", "url": "https://www.uniprot.org/uniprotkb/P50107" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "P50107", "url": "https://www.uniprot.org/uniprotkb/P50107" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P50107", "url": "https://www.uniprot.org/uniprotkb/P50107" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P50107", "url": "https://www.uniprot.org/uniprotkb/P50107" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P50107", "url": "https://www.uniprot.org/uniprotkb/P50107" } ], "pmid": "" }, { "name": "lactoylglutathione lyase activity", "id": "GO:0004462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004462", "evidence": [ { "database": "UniProtKB", "id": "P50107", "url": "https://www.uniprot.org/uniprotkb/P50107" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50107-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004463", "url": "https://www.yeastgenome.org/locus/S000004463" }, { "database": "iPTMnet", "id": "P50107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50107" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50107-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004463", "url": "https://www.yeastgenome.org/locus/S000004463" }, { "database": "iPTMnet", "id": "P50107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50107" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50107-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Ser178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004463", "url": "https://www.yeastgenome.org/locus/S000004463" }, { "database": "iPTMnet", "id": "P50107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50107" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50107-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004463", "url": "https://www.yeastgenome.org/locus/S000004463" }, { "database": "iPTMnet", "id": "P50107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50107" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50107-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Ser295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50107" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004463", "url": "https://www.yeastgenome.org/locus/S000004463" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50107-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004463", "url": "https://www.yeastgenome.org/locus/S000004463" }, { "database": "iPTMnet", "id": "P50107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50107" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50107-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004463", "url": "https://www.yeastgenome.org/locus/S000004463" }, { "database": "iPTMnet", "id": "P50107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50107" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50107-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Thr6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004463", "url": "https://www.yeastgenome.org/locus/S000004463" }, { "database": "iPTMnet", "id": "P50107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50107" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P50107-1" }, { "uniprot_canonical_ac": "P50264-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50264", "url": "https://www.uniprot.org/uniprotkb/P50264" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 508, "chemical_mass": 57806.0, "gene_names": "FMS1;FMS1;YM9711.09", "protein_name": "Polyamine oxidase FMS1", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060693", "name": "Brunner Syndrome", "description": "An amino acid metabolic disorder characterized by recessive X-linked inheritance, impaired monoamine metabolism, impulsive aggressiveness and mild mental retardation that has_material_basis_in mutation in the MAOA gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0060693", "evidence": [ { "id": "0060693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060693" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:594", "name": "panic disorder", "description": "An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress.", "url": "https://disease-ontology.org/term/DOID:594", "evidence": [ { "id": "594", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:594" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:768", "name": "retinoblastoma", "description": "A retinal cell cancer and malignant neoplasm of retina and neuroblastoma and neuroendocrine tumors that derives_from the tissues of the retina.", "url": "https://disease-ontology.org/term/DOID:768", "evidence": [ { "id": "768", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:768" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:986", "name": "alopecia areata", "description": "An autoimmune disease resulting in the loss of hair on the scalp and elsewhere on the body initially causing bald spots.", "url": "https://disease-ontology.org/term/DOID:986", "evidence": [ { "id": "986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:986" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P50264", "url": "https://www.uniprot.org/uniprotkb/P50264" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "P50264", "url": "https://www.uniprot.org/uniprotkb/P50264" } ], "pmid": "" }, { "name": "polyamine oxidase activity", "id": "GO:0046592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046592", "evidence": [ { "database": "UniProtKB", "id": "P50264", "url": "https://www.uniprot.org/uniprotkb/P50264" } ], "pmid": "" }, { "name": "spermine oxidase activity", "id": "GO:0052901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052901", "evidence": [ { "database": "UniProtKB", "id": "P50264", "url": "https://www.uniprot.org/uniprotkb/P50264" } ], "pmid": "" }, { "name": "N(1)-acetylpolyamine oxidase (3-acetamidopropanal-forming) activity", "id": "GO:0052903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052903", "evidence": [ { "database": "UniProtKB", "id": "P50264", "url": "https://www.uniprot.org/uniprotkb/P50264" } ], "pmid": "" }, { "name": "N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity", "id": "GO:0052897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052897", "evidence": [ { "database": "UniProtKB", "id": "P50264", "url": "https://www.uniprot.org/uniprotkb/P50264" } ], "pmid": "" } ], "biological_process": [ { "name": "spermine catabolic process", "id": "GO:0046208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046208", "evidence": [ { "database": "UniProtKB", "id": "P50264", "url": "https://www.uniprot.org/uniprotkb/P50264" } ], "pmid": "" }, { "name": "pantothenate biosynthetic process", "id": "GO:0015940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015940", "evidence": [ { "database": "UniProtKB", "id": "P50264", "url": "https://www.uniprot.org/uniprotkb/P50264" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50264-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004622", "url": "https://www.yeastgenome.org/locus/S000004622" }, { "database": "iPTMnet", "id": "P50264", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50264" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P50264-1" }, { "uniprot_canonical_ac": "P50275-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 885, "chemical_mass": 101624.0, "gene_names": "ASE1;ASE1;YOR29-09", "protein_name": "Anaphase spindle elongation protein", "disease": [], "biological_process": [ { "name": "septum digestion after cytokinesis", "id": "GO:0000920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000920", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "mitotic spindle midzone assembly", "id": "GO:0051256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051256", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "spindle midzone assembly", "id": "GO:0051255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051255", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "mitotic spindle elongation", "id": "GO:0000022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000022", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "initial mitotic spindle pole body separation", "id": "GO:0000073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000073", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "mitotic spindle midzone", "id": "GO:1990023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990023", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" }, { "name": "nuclear microtubule", "id": "GO:0005880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005880", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50275-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P50275", "url": "https://www.uniprot.org/uniprotkb/P50275" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Thr23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Thr24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Ser337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17765685", "url": "https://glygen.org/publication/PubMed/17765685" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Thr3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "524", "end_pos": "524", "site_lbl": "Thr524", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17765685", "url": "https://glygen.org/publication/PubMed/17765685" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Thr55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "675", "end_pos": "675", "site_lbl": "Thr675", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "680", "end_pos": "680", "site_lbl": "Thr680", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17765685", "url": "https://glygen.org/publication/PubMed/17765685" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "690", "end_pos": "690", "site_lbl": "Ser690", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "694", "end_pos": "694", "site_lbl": "Ser694", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "707", "end_pos": "707", "site_lbl": "Ser707", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "733", "end_pos": "733", "site_lbl": "Thr733", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17765685", "url": "https://glygen.org/publication/PubMed/17765685" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "739", "end_pos": "739", "site_lbl": "Ser739", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "740", "end_pos": "740", "site_lbl": "Ser740", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "744", "end_pos": "744", "site_lbl": "Ser744", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "745", "end_pos": "745", "site_lbl": "Ser745", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "803", "end_pos": "803", "site_lbl": "Ser803", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "809", "end_pos": "809", "site_lbl": "Ser809", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17765685", "url": "https://glygen.org/publication/PubMed/17765685" }, { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "819", "end_pos": "819", "site_lbl": "Ser819", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "17562791", "url": "https://glygen.org/publication/PubMed/17562791" }, { "database": "PubMed", "id": "19686685", "url": "https://glygen.org/publication/PubMed/19686685" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "832", "end_pos": "832", "site_lbl": "Ser832", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P50275-1", "start_pos": "834", "end_pos": "834", "site_lbl": "Ser834", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005584", "url": "https://www.yeastgenome.org/locus/S000005584" }, { "database": "iPTMnet", "id": "P50275", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P50275-1" }, { "uniprot_canonical_ac": "P50623-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50623", "url": "https://www.uniprot.org/uniprotkb/P50623" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 157, "chemical_mass": 17911.0, "gene_names": "UBC9;UBC9", "protein_name": "SUMO-conjugating enzyme UBC9", "disease": [ { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2531", "name": "hematologic cancer", "description": "An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.", "url": "https://disease-ontology.org/term/DOID:2531", "evidence": [ { "id": "2531", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2531" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "P50623", "url": "https://www.uniprot.org/uniprotkb/P50623" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P50623", "url": "https://www.uniprot.org/uniprotkb/P50623" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P50623", "url": "https://www.uniprot.org/uniprotkb/P50623" } ], "pmid": "" }, { "name": "SUMO transferase activity", "id": "GO:0019789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019789", "evidence": [ { "database": "UniProtKB", "id": "P50623", "url": "https://www.uniprot.org/uniprotkb/P50623" } ], "pmid": "" }, { "name": "SUMO conjugating enzyme activity", "id": "GO:0061656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061656", "evidence": [ { "database": "UniProtKB", "id": "P50623", "url": "https://www.uniprot.org/uniprotkb/P50623" } ], "pmid": "" } ], "biological_process": [ { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "P50623", "url": "https://www.uniprot.org/uniprotkb/P50623" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P50623", "url": "https://www.uniprot.org/uniprotkb/P50623" } ], "pmid": "" }, { "name": "mitotic spindle elongation", "id": "GO:0000022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000022", "evidence": [ { "database": "UniProtKB", "id": "P50623", "url": "https://www.uniprot.org/uniprotkb/P50623" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50623-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002222", "url": "https://www.yeastgenome.org/locus/S000002222" }, { "database": "iPTMnet", "id": "P50623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50623" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50623-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002222", "url": "https://www.yeastgenome.org/locus/S000002222" }, { "database": "iPTMnet", "id": "P50623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50623" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P50623-1" }, { "uniprot_canonical_ac": "P50861-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50861", "url": "https://www.uniprot.org/uniprotkb/P50861" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 169, "chemical_mass": 18556.0, "gene_names": "RIB4;RIB4", "protein_name": "6,7-dimethyl-8-ribityllumazine synthase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P50861", "url": "https://www.uniprot.org/uniprotkb/P50861" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P50861", "url": "https://www.uniprot.org/uniprotkb/P50861" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P50861", "url": "https://www.uniprot.org/uniprotkb/P50861" } ], "pmid": "" }, { "name": "riboflavin synthase complex", "id": "GO:0009349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009349", "evidence": [ { "database": "UniProtKB", "id": "P50861", "url": "https://www.uniprot.org/uniprotkb/P50861" } ], "pmid": "" } ], "biological_process": [ { "name": "riboflavin biosynthetic process", "id": "GO:0009231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009231", "evidence": [ { "database": "UniProtKB", "id": "P50861", "url": "https://www.uniprot.org/uniprotkb/P50861" } ], "pmid": "" } ], "molecular_function": [ { "name": "6,7-dimethyl-8-ribityllumazine synthase activity", "id": "GO:0000906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000906", "evidence": [ { "database": "UniProtKB", "id": "P50861", "url": "https://www.uniprot.org/uniprotkb/P50861" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50861-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005503", "url": "https://www.yeastgenome.org/locus/S000005503" }, { "database": "iPTMnet", "id": "P50861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50861" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P50861-1" }, { "uniprot_canonical_ac": "P50945-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50945", "url": "https://www.uniprot.org/uniprotkb/P50945" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 234, "chemical_mass": 26960.0, "gene_names": "MIC27;AIM37;MCS27;MIC27;N2190", "protein_name": "MICOS complex subunit MIC27", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P50945", "url": "https://www.uniprot.org/uniprotkb/P50945" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P50945", "url": "https://www.uniprot.org/uniprotkb/P50945" } ], "pmid": "" }, { "name": "mitochondrial crista junction", "id": "GO:0044284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044284", "evidence": [ { "database": "UniProtKB", "id": "P50945", "url": "https://www.uniprot.org/uniprotkb/P50945" } ], "pmid": "" }, { "name": "MICOS complex", "id": "GO:0061617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061617", "evidence": [ { "database": "UniProtKB", "id": "P50945", "url": "https://www.uniprot.org/uniprotkb/P50945" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of protein oligomerization", "id": "GO:0032461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032461", "evidence": [ { "database": "UniProtKB", "id": "P50945", "url": "https://www.uniprot.org/uniprotkb/P50945" } ], "pmid": "" }, { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "P50945", "url": "https://www.uniprot.org/uniprotkb/P50945" } ], "pmid": "" }, { "name": "protein-containing complex organization", "id": "GO:0043933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043933", "evidence": [ { "database": "UniProtKB", "id": "P50945", "url": "https://www.uniprot.org/uniprotkb/P50945" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P50945-1" }, { "uniprot_canonical_ac": "P50947-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 330, "chemical_mass": 37024.0, "gene_names": "PHO23;N2205;PHO23", "protein_name": "Transcriptional regulatory protein PHO23", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1749", "name": "squamous cell carcinoma", "description": "A carcinoma that derives_from squamous epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1749", "evidence": [ { "id": "1749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1749" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 }, { "disease_id": "DOID:5520", "name": "head and neck squamous cell carcinoma", "description": "A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck.", "url": "https://disease-ontology.org/term/DOID:5520", "evidence": [ { "id": "5520", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5520" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "Rpd3L-Expanded complex", "id": "GO:0070210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070210", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "Rpd3L complex", "id": "GO:0033698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033698", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase I", "id": "GO:0016479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016479", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "negative regulation of rDNA heterochromatin formation", "id": "GO:0061188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061188", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "negative regulation of silent mating-type cassette heterochromatin formation", "id": "GO:0061186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061186", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "positive regulation of invasive growth in response to glucose limitation", "id": "GO:2000219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000219", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" }, { "name": "histone H3K4me3 reader activity", "id": "GO:0140002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140002", "evidence": [ { "database": "UniProtKB", "id": "P50947", "url": "https://www.uniprot.org/uniprotkb/P50947" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P50947-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Ser252", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 252, "start_aa": "Ser", "end_pos": 252, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser252", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P50947", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P50947" } ] } ] }, { "uniprot_canonical_ac": "P50947-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Ser255", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 255, "start_aa": "Ser", "end_pos": 255, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser255", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P50947", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P50947" } ] } ] }, { "uniprot_canonical_ac": "P50947-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005041", "url": "https://www.yeastgenome.org/locus/S000005041" }, { "database": "iPTMnet", "id": "P50947", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50947" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50947-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Thr231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005041", "url": "https://www.yeastgenome.org/locus/S000005041" }, { "database": "iPTMnet", "id": "P50947", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50947" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50947-1", "start_pos": "234", "end_pos": "234", "site_lbl": "Ser234", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50947", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50947" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005041", "url": "https://www.yeastgenome.org/locus/S000005041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50947-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Thr237", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P50947", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50947" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P50947-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005041", "url": "https://www.yeastgenome.org/locus/S000005041" }, { "database": "iPTMnet", "id": "P50947", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50947" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50947-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Ser264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005041", "url": "https://www.yeastgenome.org/locus/S000005041" }, { "database": "iPTMnet", "id": "P50947", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50947" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P50947-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005041", "url": "https://www.yeastgenome.org/locus/S000005041" }, { "database": "iPTMnet", "id": "P50947", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P50947" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P50947-1" }, { "uniprot_canonical_ac": "P51402-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P51402", "url": "https://www.uniprot.org/uniprotkb/P51402" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 88, "chemical_mass": 9868.0, "gene_names": "RPL37B;D9719.6;RPL35B;RPL37B", "protein_name": "Large ribosomal subunit protein eL37B", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P51402", "url": "https://www.uniprot.org/uniprotkb/P51402" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P51402", "url": "https://www.uniprot.org/uniprotkb/P51402" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "P51402", "url": "https://www.uniprot.org/uniprotkb/P51402" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P51402", "url": "https://www.uniprot.org/uniprotkb/P51402" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P51402", "url": "https://www.uniprot.org/uniprotkb/P51402" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P51402", "url": "https://www.uniprot.org/uniprotkb/P51402" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P51402", "url": "https://www.uniprot.org/uniprotkb/P51402" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P51402", "url": "https://www.uniprot.org/uniprotkb/P51402" } ], "pmid": "" }, { "name": "cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000448", "evidence": [ { "database": "UniProtKB", "id": "P51402", "url": "https://www.uniprot.org/uniprotkb/P51402" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P51402-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Thr17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Thr44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Thr80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P51402-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002908", "url": "https://www.yeastgenome.org/locus/S000002908" }, { "database": "iPTMnet", "id": "P51402", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51402" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P51402-1" }, { "uniprot_canonical_ac": "P51601-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 243, "chemical_mass": 27769.0, "gene_names": "FOL2;FOL2;G9349", "protein_name": "GTP cyclohydrolase 1", "disease": [ { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:0090043", "name": "dopa-responsive dystonia", "description": "A dystonia characterized by generalized dystonia, diurnal fluctuation of symptoms, and a dramatic therapeutic response to L-dopa that has_material_basis_in heterozygous mutation in the GCH1 gene on chromosome 14q13.", "url": "https://disease-ontology.org/term/DOID:0090043", "evidence": [ { "id": "0090043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090043" } ], "weight": 0.0 }, { "disease_id": "DOID:0112225", "name": "BH4-deficient hyperphenylalaninemia B", "description": "A tetrahydrobiopterin (BH4)-deficient hyperphenylalaninemia that is characterized by hyperphenylalaninemia, depletion of the neurotransmitters dopamine and serotonin, and progressive cognitive and motor deficits that has_material_basis_in homozygous or compound heterozygous mutation in the GCH1 gene on chromosome 14q22.2.", "url": "https://disease-ontology.org/term/DOID:0112225", "evidence": [ { "id": "0112225", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112225" } ], "weight": 0.0 }, { "disease_id": "DOID:10762", "name": "portal hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:10762", "evidence": [ { "id": "10762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10762" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10923", "name": "sickle cell anemia", "description": "A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain.", "url": "https://disease-ontology.org/term/DOID:10923", "evidence": [ { "id": "10923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10923" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:11713", "name": "diabetic angiopathy", "description": "A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes.", "url": "https://disease-ontology.org/term/DOID:11713", "evidence": [ { "id": "11713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11713" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:5295", "name": "intestinal disease", "description": "A gastrointestinal system disease that is located_in the intestine.", "url": "https://disease-ontology.org/term/DOID:5295", "evidence": [ { "id": "5295", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5295" } ], "weight": 0.0 }, { "disease_id": "DOID:543", "name": "dystonia", "description": "A movement disease that is characterized by involuntary muscle contractions causing repetitive or twisting movements.", "url": "https://disease-ontology.org/term/DOID:543", "evidence": [ { "id": "543", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:543" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "tetrahydrofolate biosynthetic process", "id": "GO:0046654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046654", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" } ], "pmid": "" }, { "name": "tetrahydrobiopterin biosynthetic process", "id": "GO:0006729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006729", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" } ], "pmid": "" }, { "name": "folic acid-containing compound biosynthetic process", "id": "GO:0009396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009396", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" } ], "pmid": "" }, { "name": "folic acid biosynthetic process", "id": "GO:0046656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046656", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" } ], "pmid": "" }, { "name": "GTP cyclohydrolase I activity", "id": "GO:0003934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003934", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P51601-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51601" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003499", "url": "https://www.yeastgenome.org/locus/S000003499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51601-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003499", "url": "https://www.yeastgenome.org/locus/S000003499" }, { "database": "iPTMnet", "id": "P51601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51601" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51601-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Thr15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P51601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51601" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003499", "url": "https://www.yeastgenome.org/locus/S000003499" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51601-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003499", "url": "https://www.yeastgenome.org/locus/S000003499" }, { "database": "iPTMnet", "id": "P51601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51601" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51601-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P51601", "url": "https://www.uniprot.org/uniprotkb/P51601" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P51601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51601" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003499", "url": "https://www.yeastgenome.org/locus/S000003499" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51601-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Tyr25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51601" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003499", "url": "https://www.yeastgenome.org/locus/S000003499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P51601-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Thr26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003499", "url": "https://www.yeastgenome.org/locus/S000003499" }, { "database": "iPTMnet", "id": "P51601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51601" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51601-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Thr50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003499", "url": "https://www.yeastgenome.org/locus/S000003499" }, { "database": "iPTMnet", "id": "P51601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51601" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51601-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Ser62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003499", "url": "https://www.yeastgenome.org/locus/S000003499" }, { "database": "iPTMnet", "id": "P51601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51601" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51601-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Thr84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003499", "url": "https://www.yeastgenome.org/locus/S000003499" }, { "database": "iPTMnet", "id": "P51601", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51601" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P51601-1" }, { "uniprot_canonical_ac": "P51862-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1356, "chemical_mass": 152596.0, "gene_names": "ROM2;L8039.3;ROM2", "protein_name": "RHO1 GDP-GTP exchange protein 2", "disease": [ { "disease_id": "DOID:0110192", "name": "Charcot-Marie-Tooth disease type 4H", "description": "A Charcot-Marie-Tooth disease type 4 that has_material_basis_in mutations in the gene encoding frabin (FGD4).", "url": "https://disease-ontology.org/term/DOID:0110192", "evidence": [ { "id": "0110192", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110192" } ], "weight": 0.0 }, { "disease_id": "DOID:10595", "name": "Charcot-Marie-Tooth disease", "description": "A neuromuscular disease that is characterized by a slowly progressive degeneration of the muscles of the foot, lower leg, hand and forearm.", "url": "https://disease-ontology.org/term/DOID:10595", "evidence": [ { "id": "10595", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10595" } ], "weight": 0.0 }, { "disease_id": "DOID:6683", "name": "X-linked Aarskog syndrome", "description": "A syndromic X-linked intellectual disability affects a person's height, muscles, skeleton, genitals, and appearance of the face.", "url": "https://disease-ontology.org/term/DOID:6683", "evidence": [ { "id": "6683", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6683" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "positive regulation of endocytosis", "id": "GO:0045807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045807", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "regulation of fungal-type cell wall organization", "id": "GO:0060237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060237", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "regulation of cell wall organization or biogenesis", "id": "GO:1903338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903338", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" }, { "name": "positive regulation of mitotic actomyosin contractile ring assembly", "id": "GO:1903501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903501", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P51862-1", "start_pos": "1080", "end_pos": "1080", "site_lbl": "Thr1080", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "1091", "end_pos": "1091", "site_lbl": "Thr1091", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "1155", "end_pos": "1155", "site_lbl": "Thr1155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "1158", "end_pos": "1158", "site_lbl": "Ser1158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "1159", "end_pos": "1159", "site_lbl": "Ser1159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "1160", "end_pos": "1160", "site_lbl": "Ser1160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "1162", "end_pos": "1162", "site_lbl": "Ser1162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Thr122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Ser207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Ser212", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Thr215", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Thr216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Thr218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Ser223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Ser289", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Ser291", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Ser294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Thr296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Ser360", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Thr369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "373", "end_pos": "373", "site_lbl": "Ser373", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Thr374", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Ser375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Thr382", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Ser383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Ser385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Thr387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Ser390", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "391", "end_pos": "391", "site_lbl": "Ser391", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Ser395", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Thr398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Ser403", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Ser494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Ser551", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Ser564", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "565", "end_pos": "565", "site_lbl": "Ser565", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "566", "end_pos": "566", "site_lbl": "Ser566", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "568", "end_pos": "568", "site_lbl": "Ser568", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "628", "end_pos": "628", "site_lbl": "Ser628", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Ser640", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P51862", "url": "https://www.uniprot.org/uniprotkb/P51862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51862-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004363", "url": "https://www.yeastgenome.org/locus/S000004363" }, { "database": "iPTMnet", "id": "P51862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51862" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P51862-1" }, { "uniprot_canonical_ac": "P51979-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1187, "chemical_mass": 135072.0, "gene_names": "HFM1;HFM1;MER3;NRE1046", "protein_name": "ATP-dependent DNA helicase MER3", "disease": [ { "disease_id": "DOID:0080866", "name": "primary ovarian insufficiency 9", "description": "A primary ovarian insufficiency that has_material_basis_in compound heterozygous mutation in the HFM1 gene on chromosome 1p22.", "url": "https://disease-ontology.org/term/DOID:0080866", "evidence": [ { "id": "0080866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080866" } ], "weight": 0.0 } ], "biological_process": [ { "name": "resolution of meiotic recombination intermediates", "id": "GO:0000712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000712", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" } ], "molecular_function": [ { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P51979-1", "start_pos": "624", "end_pos": "624", "site_lbl": "Thr624", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003220", "url": "https://www.yeastgenome.org/locus/S000003220" }, { "database": "iPTMnet", "id": "P51979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51979" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51979-1", "start_pos": "627", "end_pos": "627", "site_lbl": "Tyr627", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003220", "url": "https://www.yeastgenome.org/locus/S000003220" }, { "database": "iPTMnet", "id": "P51979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51979" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51979-1", "start_pos": "958", "end_pos": "958", "site_lbl": "Ser958", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003220", "url": "https://www.yeastgenome.org/locus/S000003220" }, { "database": "iPTMnet", "id": "P51979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51979" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51979-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Gly166", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Decrease in ATPase activity. Delayed onset of meiotic division, DNA double-stranded breaks accumulate later and to higher levels before disappearing, decreased spore viability, greatly decreased helicase and ATPase.", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" }, { "database": "PubMed", "id": "11376001", "url": "https://glygen.org/publication/PubMed/11376001" }, { "database": "PubMed", "id": "11971962", "url": "https://glygen.org/publication/PubMed/11971962" } ] } ] }, { "uniprot_canonical_ac": "P51979-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Lys167", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Delayed onset of meiotic division, DNA double-stranded breaks accumulate later and to higher levels before disappearing, decreased spore viability, loss of ATPase.", "evidence": [ { "database": "UniProtKB", "id": "P51979", "url": "https://www.uniprot.org/uniprotkb/P51979" }, { "database": "PubMed", "id": "11971962", "url": "https://glygen.org/publication/PubMed/11971962" } ] } ] } ], "record_id": "P51979-1" }, { "uniprot_canonical_ac": "P51996-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 222, "chemical_mass": 24520.0, "gene_names": "YPT32;YPT11;YPT32", "protein_name": "GTP-binding protein YPT32/YPT11", "disease": [ { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 }, { "disease_id": "DOID:10155", "name": "intestinal cancer", "description": "A gastrointestinal system cancer that is located_in the intestine.", "url": "https://disease-ontology.org/term/DOID:10155", "evidence": [ { "id": "10155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10155" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" }, { "name": "early endosome to Golgi transport", "id": "GO:0034498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034498", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P51996-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Thr203", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 203, "start_aa": "Thr", "end_pos": 203, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr203", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003178", "url": "https://www.yeastgenome.org/locus/S000003178" }, { "database": "iPTMnet", "id": "P51996", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51996" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003178", "url": "https://www.yeastgenome.org/locus/S000003178" }, { "database": "iPTMnet", "id": "P51996", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51996" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003178", "url": "https://www.yeastgenome.org/locus/S000003178" }, { "database": "iPTMnet", "id": "P51996", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51996" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Thr207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003178", "url": "https://www.yeastgenome.org/locus/S000003178" }, { "database": "iPTMnet", "id": "P51996", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51996" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P51996", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51996" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003178", "url": "https://www.yeastgenome.org/locus/S000003178" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Thr35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003178", "url": "https://www.yeastgenome.org/locus/S000003178" }, { "database": "iPTMnet", "id": "P51996", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P51996" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Asn126", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "I", "comment": "Blocks nucleotide binding.", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" }, { "database": "PubMed", "id": "12045183", "url": "https://glygen.org/publication/PubMed/12045183" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ala141", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "D", "comment": "Loss of function at 37 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" }, { "database": "PubMed", "id": "9151665", "url": "https://glygen.org/publication/PubMed/9151665" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "N", "comment": "Binds preferentially GDP.", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" }, { "database": "PubMed", "id": "12045183", "url": "https://glygen.org/publication/PubMed/12045183" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Glu49", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "Cold sensitive.", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" }, { "database": "PubMed", "id": "12045183", "url": "https://glygen.org/publication/PubMed/12045183" } ] } ] }, { "uniprot_canonical_ac": "P51996-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Gln72", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "L", "comment": "Reduces GTPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P51996", "url": "https://www.uniprot.org/uniprotkb/P51996" }, { "database": "PubMed", "id": "12045183", "url": "https://glygen.org/publication/PubMed/12045183" } ] } ] } ], "record_id": "P51996-1" }, { "uniprot_canonical_ac": "P52488-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P52488", "url": "https://www.uniprot.org/uniprotkb/P52488" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 636, "chemical_mass": 71259.0, "gene_names": "UBA2;D9509.10;PIP2;UAL1;UBA2", "protein_name": "Ubiquitin-activating enzyme E1-like", "disease": [ { "disease_id": "DOID:2531", "name": "hematologic cancer", "description": "An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.", "url": "https://disease-ontology.org/term/DOID:2531", "evidence": [ { "id": "2531", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2531" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "SUMO activating enzyme activity", "id": "GO:0019948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019948", "evidence": [ { "database": "UniProtKB", "id": "P52488", "url": "https://www.uniprot.org/uniprotkb/P52488" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P52488", "url": "https://www.uniprot.org/uniprotkb/P52488" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P52488", "url": "https://www.uniprot.org/uniprotkb/P52488" } ], "pmid": "" } ], "cellular_component": [ { "name": "SUMO activating enzyme complex", "id": "GO:0031510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031510", "evidence": [ { "database": "UniProtKB", "id": "P52488", "url": "https://www.uniprot.org/uniprotkb/P52488" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P52488", "url": "https://www.uniprot.org/uniprotkb/P52488" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P52488", "url": "https://www.uniprot.org/uniprotkb/P52488" } ], "pmid": "" } ], "biological_process": [ { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "P52488", "url": "https://www.uniprot.org/uniprotkb/P52488" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P52488-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002798", "url": "https://www.yeastgenome.org/locus/S000002798" }, { "database": "iPTMnet", "id": "P52488", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52488" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52488-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Thr288", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52488", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52488" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002798", "url": "https://www.yeastgenome.org/locus/S000002798" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P52488-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Thr290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52488", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52488" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002798", "url": "https://www.yeastgenome.org/locus/S000002798" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52488-1", "start_pos": "418", "end_pos": "418", "site_lbl": "Ser418", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002798", "url": "https://www.yeastgenome.org/locus/S000002798" }, { "database": "iPTMnet", "id": "P52488", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52488" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52488-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Ser439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002798", "url": "https://www.yeastgenome.org/locus/S000002798" }, { "database": "iPTMnet", "id": "P52488", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52488" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P52488-1", "start_pos": "555", "end_pos": "555", "site_lbl": "Ser555", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002798", "url": "https://www.yeastgenome.org/locus/S000002798" }, { "database": "iPTMnet", "id": "P52488", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52488" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52488-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Thr575", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002798", "url": "https://www.yeastgenome.org/locus/S000002798" }, { "database": "iPTMnet", "id": "P52488", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52488" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52488-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Ser577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002798", "url": "https://www.yeastgenome.org/locus/S000002798" }, { "database": "iPTMnet", "id": "P52488", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52488" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52488-1", "start_pos": "628", "end_pos": "628", "site_lbl": "Thr628", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002798", "url": "https://www.yeastgenome.org/locus/S000002798" }, { "database": "iPTMnet", "id": "P52488", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52488" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52488-1", "start_pos": "630", "end_pos": "630", "site_lbl": "Ser630", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002798", "url": "https://www.yeastgenome.org/locus/S000002798" }, { "database": "iPTMnet", "id": "P52488", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52488" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52488-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Cys177", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P52488", "url": "https://www.uniprot.org/uniprotkb/P52488" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P52488", "url": "https://www.uniprot.org/uniprotkb/P52488" } ] } ] } ], "record_id": "P52488-1" }, { "uniprot_canonical_ac": "P52489-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 506, "chemical_mass": 55195.0, "gene_names": "PYK2;O6342;PYK2", "protein_name": "Pyruvate kinase 2", "disease": [ { "disease_id": "DOID:0014667", "name": "disease of metabolism", "description": "A disease that involves errors in metabolic processes of building or degradation of molecules.", "url": "https://disease-ontology.org/term/DOID:0014667", "evidence": [ { "id": "0014667", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0014667" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0111077", "name": "congenital nonspherocytic hemolytic anemia 2", "description": "A congenital nonspherocytic hemolytic anemia that has_material_basis_in homozygous or compound heterozygous mutation in the PKLR gene on chromosome 1q22.", "url": "https://disease-ontology.org/term/DOID:0111077", "evidence": [ { "id": "0111077", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111077" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:1926", "name": "Gaucher's disease", "description": "A sphingolipidosis characterized by deficiency of the enzyme glucocerebrosidase which results in the accumulation of harmful quantities of the glycolipid glucocerebroside throughout the body, especially within the bone marrow, spleen and liver.", "url": "https://disease-ontology.org/term/DOID:1926", "evidence": [ { "id": "1926", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1926" } ], "weight": 0.0 }, { "disease_id": "DOID:2861", "name": "congenital nonspherocytic hemolytic anemia", "description": "", "url": "https://disease-ontology.org/term/DOID:2861", "evidence": [ { "id": "2861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2861" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" } ], "pmid": "" }, { "name": "potassium ion binding", "id": "GO:0030955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030955", "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" } ], "pmid": "" }, { "name": "melatonin binding", "id": "GO:1904408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904408", "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" } ], "pmid": "" }, { "name": "pyruvate kinase activity", "id": "GO:0004743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004743", "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" } ], "pmid": "" } ], "biological_process": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P52489-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Thr16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005874", "url": "https://www.yeastgenome.org/locus/S000005874" }, { "database": "iPTMnet", "id": "P52489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52489" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52489-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005874", "url": "https://www.yeastgenome.org/locus/S000005874" }, { "database": "iPTMnet", "id": "P52489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52489" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52489-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P52489", "url": "https://www.uniprot.org/uniprotkb/P52489" }, { "database": "iPTMnet", "id": "P52489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52489" }, { "database": "PubMed", "id": "20639203", "url": "https://glygen.org/publication/PubMed/20639203" }, { "database": "SGD", "id": "S000005874", "url": "https://www.yeastgenome.org/locus/S000005874" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52489-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Ser318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005874", "url": "https://www.yeastgenome.org/locus/S000005874" }, { "database": "iPTMnet", "id": "P52489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52489" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52489-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Ser334", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005874", "url": "https://www.yeastgenome.org/locus/S000005874" }, { "database": "iPTMnet", "id": "P52489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52489" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52489-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Thr337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005874", "url": "https://www.yeastgenome.org/locus/S000005874" }, { "database": "iPTMnet", "id": "P52489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52489" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52489-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005874", "url": "https://www.yeastgenome.org/locus/S000005874" }, { "database": "iPTMnet", "id": "P52489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52489" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P52489-1" }, { "uniprot_canonical_ac": "P52490-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 153, "chemical_mass": 17468.0, "gene_names": "UBC13;UBC13;YD6652.04", "protein_name": "Ubiquitin-conjugating enzyme E2 13", "disease": [], "cellular_component": [ { "name": "ubiquitin conjugating enzyme complex", "id": "GO:0031371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031371", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" } ], "biological_process": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" }, { "name": "free ubiquitin chain polymerization", "id": "GO:0010994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010994", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" }, { "name": "DNA damage tolerance", "id": "GO:0006301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006301", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" }, { "name": "protein targeting to vacuolar membrane", "id": "GO:0044395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044395", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P52490-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002499", "url": "https://www.yeastgenome.org/locus/S000002499" }, { "database": "iPTMnet", "id": "P52490", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52490" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52490-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ala110", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "R", "comment": "Lowers rate of ubiquitin chain elongation. No effect on thioester formation at the active site.", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ] } ] }, { "uniprot_canonical_ac": "P52490-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Glu55", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Strongly reduces MMS2 binding and interferes with error-free DNA repair.", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" }, { "database": "PubMed", "id": "11440714", "url": "https://glygen.org/publication/PubMed/11440714" } ] } ] }, { "uniprot_canonical_ac": "P52490-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Asp81", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "R", "comment": "Abolishes ubiquitin chain elongation. No effect on thioester formation at the active site.", "evidence": [ { "database": "UniProtKB", "id": "P52490", "url": "https://www.uniprot.org/uniprotkb/P52490" } ] } ] } ], "record_id": "P52490-1" }, { "uniprot_canonical_ac": "P52593-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1655, "chemical_mass": 188577.0, "gene_names": "NUP188;NUP188", "protein_name": "Nucleoporin NUP188", "disease": [], "biological_process": [ { "name": "nuclear pore organization", "id": "GO:0006999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006999", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "pmid": "" }, { "name": "mRNA export from nucleus in response to heat stress", "id": "GO:0031990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031990", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "pmid": "" }, { "name": "nuclear pore inner ring", "id": "GO:0044611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044611", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P52593-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Thr3", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3, "start_aa": "Thr", "end_pos": 3, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P52593-1", "start_pos": "1072", "end_pos": "1072", "site_lbl": "Tyr1072", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004571", "url": "https://www.yeastgenome.org/locus/S000004571" }, { "database": "iPTMnet", "id": "P52593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52593" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52593-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Ser237", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52593" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004571", "url": "https://www.yeastgenome.org/locus/S000004571" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52593-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Ser337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52593" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004571", "url": "https://www.yeastgenome.org/locus/S000004571" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52593-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P52593", "url": "https://www.uniprot.org/uniprotkb/P52593" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P52593", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52593" }, { "database": "SGD", "id": "S000004571", "url": "https://www.yeastgenome.org/locus/S000004571" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P52593-1" }, { "uniprot_canonical_ac": "P52871-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P52871", "url": "https://www.uniprot.org/uniprotkb/P52871" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 88, "chemical_mass": 9606.0, "gene_names": "SBH2;SBH2;SEB2;YER019BC", "protein_name": "Protein transport protein SBH2", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P52871", "url": "https://www.uniprot.org/uniprotkb/P52871" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P52871", "url": "https://www.uniprot.org/uniprotkb/P52871" } ], "pmid": "" }, { "name": "Sec61 translocon complex", "id": "GO:0005784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005784", "evidence": [ { "database": "UniProtKB", "id": "P52871", "url": "https://www.uniprot.org/uniprotkb/P52871" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "P52871", "url": "https://www.uniprot.org/uniprotkb/P52871" } ], "pmid": "" }, { "name": "Ssh1 translocon complex", "id": "GO:0071261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071261", "evidence": [ { "database": "UniProtKB", "id": "P52871", "url": "https://www.uniprot.org/uniprotkb/P52871" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "P52871", "url": "https://www.uniprot.org/uniprotkb/P52871" } ], "pmid": "" } ], "biological_process": [ { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "P52871", "url": "https://www.uniprot.org/uniprotkb/P52871" } ], "pmid": "" }, { "name": "post-translational protein targeting to membrane, translocation", "id": "GO:0031204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031204", "evidence": [ { "database": "UniProtKB", "id": "P52871", "url": "https://www.uniprot.org/uniprotkb/P52871" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, translocation", "id": "GO:0006616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006616", "evidence": [ { "database": "UniProtKB", "id": "P52871", "url": "https://www.uniprot.org/uniprotkb/P52871" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P52871-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002127", "url": "https://www.yeastgenome.org/locus/S000002127" }, { "database": "iPTMnet", "id": "P52871", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52871" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P52871-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Thr30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002127", "url": "https://www.yeastgenome.org/locus/S000002127" }, { "database": "iPTMnet", "id": "P52871", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52871" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P52871-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002127", "url": "https://www.yeastgenome.org/locus/S000002127" }, { "database": "iPTMnet", "id": "P52871", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52871" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P52871-1" }, { "uniprot_canonical_ac": "P52910-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 683, "chemical_mass": 75492.0, "gene_names": "ACS2;ACS2;L9634.10", "protein_name": "Acetyl-coenzyme A synthetase 2", "disease": [ { "disease_id": "DOID:0050567", "name": "orofacial cleft", "description": "A physical disorder that is characterized by cleft lip and/or cleft palate that result in feeding, speech and hearing problems caused by failures during development.", "url": "https://disease-ontology.org/term/DOID:0050567", "evidence": [ { "id": "0050567", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050567" } ], "weight": 0.0 }, { "disease_id": "DOID:11981", "name": "morbid obesity", "description": "", "url": "https://disease-ontology.org/term/DOID:11981", "evidence": [ { "id": "11981", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11981" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:3319", "name": "lymphangioleiomyomatosis", "description": "A lung disease that is characterized by progressive cystic destruction of the lung and lymphatic abnormalities, frequently associated with renal angiomyolipomas.", "url": "https://disease-ontology.org/term/DOID:3319", "evidence": [ { "id": "3319", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3319" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" }, { "name": "AMP binding", "id": "GO:0016208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016208", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" }, { "name": "acetate-CoA ligase activity", "id": "GO:0003987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003987", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" }, { "name": "acid-ammonia (or amide) ligase activity", "id": "GO:0016880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016880", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" }, { "name": "acetyl-CoA biosynthetic process", "id": "GO:0006085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006085", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" }, { "name": "pyruvate metabolic process", "id": "GO:0006090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006090", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" }, { "name": "acetyl-CoA biosynthetic process from acetate", "id": "GO:0019427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019427", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P52910-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Tyr153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Ser228", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Thr236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Thr238", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "373", "end_pos": "373", "site_lbl": "Thr373", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Ser392", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Ser405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ser484", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Ser488", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Ser539", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Ser544", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "545", "end_pos": "545", "site_lbl": "Thr545", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "546", "end_pos": "546", "site_lbl": "Ser546", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Thr599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Ser620", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "679", "end_pos": "679", "site_lbl": "Ser679", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P52910", "url": "https://www.uniprot.org/uniprotkb/P52910" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52910-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Ser93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004143", "url": "https://www.yeastgenome.org/locus/S000004143" }, { "database": "iPTMnet", "id": "P52910", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52910" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P52910-1" }, { "uniprot_canonical_ac": "P52919-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P52919", "url": "https://www.uniprot.org/uniprotkb/P52919" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 319, "chemical_mass": 37354.0, "gene_names": "NBP1;L9122.6;NBP1", "protein_name": "NAP1-binding protein", "disease": [], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "P52919", "url": "https://www.uniprot.org/uniprotkb/P52919" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "P52919", "url": "https://www.uniprot.org/uniprotkb/P52919" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P52919", "url": "https://www.uniprot.org/uniprotkb/P52919" } ], "pmid": "" }, { "name": "central plaque of spindle pole body", "id": "GO:0005823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005823", "evidence": [ { "database": "UniProtKB", "id": "P52919", "url": "https://www.uniprot.org/uniprotkb/P52919" } ], "pmid": "" } ], "biological_process": [ { "name": "spindle pole body duplication", "id": "GO:0030474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030474", "evidence": [ { "database": "UniProtKB", "id": "P52919", "url": "https://www.uniprot.org/uniprotkb/P52919" } ], "pmid": "" }, { "name": "spindle pole body localization", "id": "GO:0070631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070631", "evidence": [ { "database": "UniProtKB", "id": "P52919", "url": "https://www.uniprot.org/uniprotkb/P52919" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P52919-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Thr292", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P52919", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P52919" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Thr62", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P52919", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P52919" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Thr107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Ser169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "234", "end_pos": "234", "site_lbl": "Ser234", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Ser251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P52919", "url": "https://www.uniprot.org/uniprotkb/P52919" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Ser253", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Thr258", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Ser260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P52919", "url": "https://www.uniprot.org/uniprotkb/P52919" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Thr263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Ser264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Ser287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Tyr295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Thr73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826" } ] } ] }, { "uniprot_canonical_ac": "P52919-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Ser97", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004449", "url": "https://www.yeastgenome.org/locus/S000004449" }, { "database": "iPTMnet", "id": "P52919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52919" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P52919-1" }, { "uniprot_canonical_ac": "P52920-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 328, "chemical_mass": 35253.0, "gene_names": "NBP35;NBP35", "protein_name": "Cytosolic Fe-S cluster assembly factor NBP35", "disease": [], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" }, { "name": "ATP-dependent FeS chaperone activity", "id": "GO:0140663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140663", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" }, { "name": "cytosolic [4Fe-4S] assembly scaffold complex", "id": "GO:1904564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904564", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P52920-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Thr267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003059", "url": "https://www.yeastgenome.org/locus/S000003059" }, { "database": "iPTMnet", "id": "P52920", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52920" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52920-1", "start_pos": "234", "end_pos": "234", "site_lbl": "Cys234", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Does not impair function.", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" } ] } ] }, { "uniprot_canonical_ac": "P52920-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Cys253", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss fo function and disrupts heterotetramer formation.", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" }, { "database": "PubMed", "id": "17401378", "url": "https://glygen.org/publication/PubMed/17401378" } ] } ] }, { "uniprot_canonical_ac": "P52920-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Cys256", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of function and disrupts heterotetramer formation.", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" } ] } ] }, { "uniprot_canonical_ac": "P52920-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Cys27", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Supports growth, albeit at a lower rate.", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" } ] } ] }, { "uniprot_canonical_ac": "P52920-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Cys295", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Does not impair function.", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" } ] } ] }, { "uniprot_canonical_ac": "P52920-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Cys41", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" } ] } ] }, { "uniprot_canonical_ac": "P52920-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Cys44", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" }, { "database": "PubMed", "id": "9290212", "url": "https://glygen.org/publication/PubMed/9290212" } ] }, { "sequence_org": "C", "sequence_mut": "G", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" }, { "database": "PubMed", "id": "9290212", "url": "https://glygen.org/publication/PubMed/9290212" } ] } ] }, { "uniprot_canonical_ac": "P52920-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Cys50", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" }, { "database": "PubMed", "id": "22362766", "url": "https://glygen.org/publication/PubMed/22362766" } ] } ] }, { "uniprot_canonical_ac": "P52920-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Lys86", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "Q", "comment": "Lethal.", "evidence": [ { "database": "UniProtKB", "id": "P52920", "url": "https://www.uniprot.org/uniprotkb/P52920" }, { "database": "PubMed", "id": "9290212", "url": "https://glygen.org/publication/PubMed/9290212" } ] } ] } ], "record_id": "P52920-1" }, { "uniprot_canonical_ac": "P52960-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 996, "chemical_mass": 114711.0, "gene_names": "PIP2;OAF2;PIP2", "protein_name": "Peroxisome proliferation transcriptional regulator", "disease": [], "biological_process": [ { "name": "cellular response to oleic acid", "id": "GO:0071400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071400", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" }, { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" }, { "name": "positive regulation of fatty acid beta-oxidation", "id": "GO:0032000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032000", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" }, { "name": "peroxisome organization", "id": "GO:0007031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007031", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" }, { "name": "Pip2-Oaf1 complex", "id": "GO:0089716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089716", "evidence": [ { "database": "UniProtKB", "id": "P52960", "url": "https://www.uniprot.org/uniprotkb/P52960" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P52960-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Thr154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005890", "url": "https://www.yeastgenome.org/locus/S000005890" }, { "database": "iPTMnet", "id": "P52960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52960" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P52960-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Thr158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P52960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52960" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P52960-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005890", "url": "https://www.yeastgenome.org/locus/S000005890" }, { "database": "iPTMnet", "id": "P52960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52960" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P52960-1" }, { "uniprot_canonical_ac": "P53008-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 833, "chemical_mass": 96507.0, "gene_names": "CWH41;CWH41;DER7;GLS1", "protein_name": "Mannosyl-oligosaccharide glucosidase", "disease": [ { "disease_id": "DOID:0070254", "name": "congenital disorder of glycosylation type IIb", "description": "A congenital disorder of glycosylation type II that has_material_basis_in an autosomal recessive mutation of the MOGS gene on chromosome 2p13.1.", "url": "https://disease-ontology.org/term/DOID:0070254", "evidence": [ { "id": "0070254", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070254" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" } ], "pmid": "" } ], "biological_process": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" } ], "pmid": "" }, { "name": "oligosaccharide metabolic process", "id": "GO:0009311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009311", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" } ], "pmid": "" }, { "name": "fungal-type cell wall biogenesis", "id": "GO:0009272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009272", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" } ], "pmid": "" }, { "name": "fungal-type cell wall beta-glucan biosynthetic process", "id": "GO:0070880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070880", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" } ], "pmid": "" }, { "name": "endoplasmic reticulum N-glycan trimming", "id": "GO:0140277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140277", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" } ], "pmid": "" } ], "molecular_function": [ { "name": "Glc3Man9GlcNAc2 oligosaccharide glucosidase activity", "id": "GO:0004573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004573", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53008-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Asn122", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 122, "start_aa": "Asn", "end_pos": 122, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn122", "evidence": [ { "id": "P53008", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53008#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53008-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Asn135", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 135, "start_aa": "Asn", "end_pos": 135, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn135", "evidence": [ { "id": "P53008", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53008#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53008-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Asn42", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 42, "start_aa": "Asn", "end_pos": 42, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn42", "evidence": [ { "id": "P53008", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53008#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53008-1", "start_pos": "787", "end_pos": "787", "site_lbl": "Asn787", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 787, "start_aa": "Asn", "end_pos": 787, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn787", "evidence": [ { "id": "P53008", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53008#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53008-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Tyr99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53008", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53008" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53008-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Asp601", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abrogates catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" }, { "database": "PubMed", "id": "23536181", "url": "https://glygen.org/publication/PubMed/23536181" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Abrogates catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" }, { "database": "PubMed", "id": "23536181", "url": "https://glygen.org/publication/PubMed/23536181" } ] } ] }, { "uniprot_canonical_ac": "P53008-1", "start_pos": "804", "end_pos": "804", "site_lbl": "Glu804", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Abrogates catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" }, { "database": "PubMed", "id": "23536181", "url": "https://glygen.org/publication/PubMed/23536181" } ] }, { "sequence_org": "E", "sequence_mut": "N", "comment": "Abrogates catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P53008", "url": "https://www.uniprot.org/uniprotkb/P53008" }, { "database": "PubMed", "id": "23536181", "url": "https://glygen.org/publication/PubMed/23536181" } ] } ] } ], "record_id": "P53008-1" }, { "uniprot_canonical_ac": "P53011-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 349, "chemical_mass": 39123.0, "gene_names": "SEH1;SEH1", "protein_name": "Nucleoporin SEH1", "disease": [], "biological_process": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" }, { "name": "regulation of TORC1 signaling", "id": "GO:1903432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903432", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore outer ring", "id": "GO:0031080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" }, { "name": "Seh1-associated complex", "id": "GO:0035859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035859", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53011-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53011-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Thr246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53011-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Ser250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53011-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Ser254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53011-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Ser257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53011", "url": "https://www.uniprot.org/uniprotkb/P53011" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53011-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Thr259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53011-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Ser261", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53011-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53011-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Ser280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53011-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53011-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Ser336", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003068", "url": "https://www.yeastgenome.org/locus/S000003068" }, { "database": "iPTMnet", "id": "P53011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53011-1" }, { "uniprot_canonical_ac": "P53012-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 380, "chemical_mass": 42735.0, "gene_names": "SCS3;FIT2B;G2868;SCS3", "protein_name": "Acyl-coenzyme A diphosphatase SCS3", "disease": [ { "disease_id": "DOID:0081273", "name": "Siddiqi syndrome", "description": "A lipid storage disease that is characterized by global developmental delay, early-onset progressive sensorineural hearing impairment, regression of motor skills, dystonia, poor overall growth, and low body mass index and that has_material_basis_in homozygous or compound heterozygous mutation in the FITM2 gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0081273", "evidence": [ { "id": "0081273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081273" } ], "weight": 0.0 }, { "disease_id": "DOID:3146", "name": "lipid metabolism disorder", "description": "An inherited metabolic disorder that involves the creation and degradation of lipids.", "url": "https://disease-ontology.org/term/DOID:3146", "evidence": [ { "id": "3146", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3146" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" }, { "name": "lipid droplet organization", "id": "GO:0034389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034389", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" }, { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" }, { "name": "lipid droplet formation", "id": "GO:0140042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140042", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" }, { "name": "fatty-acyl-CoA catabolic process", "id": "GO:0036115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036115", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides", "id": "GO:0016818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016818", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" }, { "name": "coenzyme A diphosphatase activity", "id": "GO:0010945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010945", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53012-1", "start_pos": "235", "end_pos": "235", "site_lbl": "His235", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Inositol auxotrophy. Impaired ER morphology with the apparition of clumps of ER membrane.", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" }, { "database": "PubMed", "id": "32915949", "url": "https://glygen.org/publication/PubMed/32915949" } ] } ] }, { "uniprot_canonical_ac": "P53012-1", "start_pos": "350", "end_pos": "350", "site_lbl": "His350", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Inositol auxotrophy. Impaired ER morphology with the apparition of clumps of ER membrane.", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" }, { "database": "PubMed", "id": "32915949", "url": "https://glygen.org/publication/PubMed/32915949" } ] } ] }, { "uniprot_canonical_ac": "P53012-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Glu354", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Temperature sensitive. Inositol auxotroph at 37 degrees Celsius, but partially supports growth on inositol at 25 degrees Celsius. Impaired ER morphology and aberrant lipid droplet (LD) budding.", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" }, { "database": "PubMed", "id": "29417057", "url": "https://glygen.org/publication/PubMed/29417057" } ] }, { "sequence_org": "E", "sequence_mut": "D", "comment": "No defect in inositol biosynthesis. Aberrant lipid droplet (LD) budding.", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" }, { "database": "PubMed", "id": "29417057", "url": "https://glygen.org/publication/PubMed/29417057" } ] }, { "sequence_org": "E", "sequence_mut": "K", "comment": "Inositol auxotrophy. Impaired ER morphology and aberrant lipid droplet (LD) budding.", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" }, { "database": "PubMed", "id": "29417057", "url": "https://glygen.org/publication/PubMed/29417057" } ] }, { "sequence_org": "E", "sequence_mut": "Q", "comment": "No defect in inositol biosynthesis. Aberrant lipid droplet (LD) budding.", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" }, { "database": "PubMed", "id": "29417057", "url": "https://glygen.org/publication/PubMed/29417057" } ] }, { "sequence_org": "E", "sequence_mut": "V", "comment": "Inositol auxotrophy. Impaired ER morphology and aberrant lipid droplet (LD) budding.", "evidence": [ { "database": "UniProtKB", "id": "P53012", "url": "https://www.uniprot.org/uniprotkb/P53012" }, { "database": "PubMed", "id": "29417057", "url": "https://glygen.org/publication/PubMed/29417057" } ] } ] } ], "record_id": "P53012-1" }, { "uniprot_canonical_ac": "P53035-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 382, "chemical_mass": 42048.0, "gene_names": "MIG2;MIG2;MLZ1", "protein_name": "Regulatory protein MIG2", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "pmid": "" }, { "name": "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation", "id": "GO:1900436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900436", "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P53035", "url": "https://www.uniprot.org/uniprotkb/P53035" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53035-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003177", "url": "https://www.yeastgenome.org/locus/S000003177" }, { "database": "iPTMnet", "id": "P53035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53035" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53035-1" }, { "uniprot_canonical_ac": "P53037-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1138, "chemical_mass": 130065.0, "gene_names": "PSD2;PSD2", "protein_name": "Phosphatidylserine decarboxylase proenzyme 2", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "pmid": "" }, { "name": "phosphatidylserine decarboxylase activity", "id": "GO:0004609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004609", "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylcholine biosynthetic process", "id": "GO:0006656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006656", "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "pmid": "" }, { "name": "protein autoprocessing", "id": "GO:0016540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016540", "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "pmid": "" }, { "name": "phosphatidylethanolamine biosynthetic process", "id": "GO:0006646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006646", "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "pmid": "" }, { "name": "intermembrane phospholipid transfer", "id": "GO:0120010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120010", "evidence": [ { "database": "UniProtKB", "id": "P53037", "url": "https://www.uniprot.org/uniprotkb/P53037" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53037-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Thr102", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 102, "start_aa": "Thr", "end_pos": 102, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr102", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Thr104", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 104, "start_aa": "Thr", "end_pos": 104, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr104", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 108, "start_aa": "Ser", "end_pos": 108, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser108", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 109, "start_aa": "Ser", "end_pos": 109, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser109", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 110, "start_aa": "Ser", "end_pos": 110, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser110", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 113, "start_aa": "Ser", "end_pos": 113, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser113", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 115, "start_aa": "Ser", "end_pos": 115, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser115", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 118, "start_aa": "Ser", "end_pos": 118, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser118", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 119, "start_aa": "Ser", "end_pos": 119, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser119", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 121, "start_aa": "Ser", "end_pos": 121, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser121", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 123, "start_aa": "Ser", "end_pos": 123, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser123", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003402", "url": "https://www.yeastgenome.org/locus/S000003402" }, { "database": "iPTMnet", "id": "P53037", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53037" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 124, "start_aa": "Ser", "end_pos": 124, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser124", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53037", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53037" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Thr148", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 148, "start_aa": "Thr", "end_pos": 148, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr148", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Thr96", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "1108", "end_pos": "1108", "site_lbl": "Ser1108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53037", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53037" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003402", "url": "https://www.yeastgenome.org/locus/S000003402" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Thr136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003402", "url": "https://www.yeastgenome.org/locus/S000003402" }, { "database": "iPTMnet", "id": "P53037", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53037" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003402", "url": "https://www.yeastgenome.org/locus/S000003402" }, { "database": "iPTMnet", "id": "P53037", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53037" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Ser290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003402", "url": "https://www.yeastgenome.org/locus/S000003402" }, { "database": "iPTMnet", "id": "P53037", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53037" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Ser471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003402", "url": "https://www.yeastgenome.org/locus/S000003402" }, { "database": "iPTMnet", "id": "P53037", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53037" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "516", "end_pos": "516", "site_lbl": "Thr516", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53037", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53037" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Tyr518", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53037", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53037" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "738", "end_pos": "738", "site_lbl": "Thr738", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003402", "url": "https://www.yeastgenome.org/locus/S000003402" }, { "database": "iPTMnet", "id": "P53037", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53037" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53037-1", "start_pos": "857", "end_pos": "857", "site_lbl": "Ser857", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003402", "url": "https://www.yeastgenome.org/locus/S000003402" }, { "database": "iPTMnet", "id": "P53037", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53037" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53037-1" }, { "uniprot_canonical_ac": "P53038-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 688, "chemical_mass": 78687.0, "gene_names": "TEL2;TEL2", "protein_name": "Telomere length regulation protein TEL2", "disease": [], "biological_process": [ { "name": "'de novo' cotranslational protein folding", "id": "GO:0051083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051083", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" }, { "name": "positive regulation of DNA damage checkpoint", "id": "GO:2000003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000003", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" }, { "name": "protein localization to chromosome", "id": "GO:0034502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034502", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" }, { "name": "telomere maintenance via telomerase", "id": "GO:0007004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007004", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" }, { "name": "TTT Hsp90 cochaperone complex", "id": "GO:0110078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110078", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" } ], "molecular_function": [ { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53038-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Ser406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53038" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003331", "url": "https://www.yeastgenome.org/locus/S000003331" } ] } ] }, { "uniprot_canonical_ac": "P53038-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Ser417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53038" }, { "database": "SGD", "id": "S000003331", "url": "https://www.yeastgenome.org/locus/S000003331" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53038-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Ser419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53038" }, { "database": "SGD", "id": "S000003331", "url": "https://www.yeastgenome.org/locus/S000003331" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53038-1", "start_pos": "333", "end_pos": "333", "site_lbl": "Leu333", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "Q", "comment": "Does not inhibit interaction with TTI1 or TTI2. Inhibits interaction with TTI1 or TTI2; when associated with E-345.", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" }, { "database": "PubMed", "id": "20801936", "url": "https://glygen.org/publication/PubMed/20801936" } ] } ] }, { "uniprot_canonical_ac": "P53038-1", "start_pos": "345", "end_pos": "345", "site_lbl": "Met345", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "E", "comment": "Does not inhibit weakly interaction with TTI1 or TTI2. Inhibits interaction with TTI1 or TTI2; when associated with Q-333.", "evidence": [ { "database": "UniProtKB", "id": "P53038", "url": "https://www.uniprot.org/uniprotkb/P53038" }, { "database": "PubMed", "id": "20801936", "url": "https://glygen.org/publication/PubMed/20801936" } ] } ] } ], "record_id": "P53038-1" }, { "uniprot_canonical_ac": "P53048-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 616, "chemical_mass": 67980.0, "gene_names": "MAL11;AGT1;MAL11;MAL1T;MTP1", "protein_name": "General alpha-glucoside permease", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate transport", "id": "GO:0008643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008643", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" }, { "name": "maltose metabolic process", "id": "GO:0000023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000023", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" }, { "name": "alpha-glucoside transport", "id": "GO:0000017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000017", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" }, { "name": "trehalose transport", "id": "GO:0015771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015771", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" }, { "name": "maltose transport", "id": "GO:0015768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015768", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" }, { "name": "disaccharide catabolic process", "id": "GO:0046352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046352", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate:proton symporter activity", "id": "GO:0005351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005351", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" }, { "name": "trehalose transmembrane transporter activity", "id": "GO:0015574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015574", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" }, { "name": "alpha-glucoside:proton symporter activity", "id": "GO:0005352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005352", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" }, { "name": "maltose:proton symporter activity", "id": "GO:0005364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005364", "evidence": [ { "database": "UniProtKB", "id": "P53048", "url": "https://www.uniprot.org/uniprotkb/P53048" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53048-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Asn523", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 523, "start_aa": "Asn", "end_pos": 523, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn523", "evidence": [ { "id": "P53048", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53048#ptm_processing" } ] } ] } ], "record_id": "P53048-1" }, { "uniprot_canonical_ac": "P53049-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1477, "chemical_mass": 166728.0, "gene_names": "YOR1;YOR1;YRS1", "protein_name": "Oligomycin resistance ATP-dependent permease YOR1", "disease": [ { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" } ], "pmid": "" }, { "name": "ABC-type glutathione S-conjugate transporter activity", "id": "GO:0015431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015431", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" } ], "pmid": "" }, { "name": "ABC-type cadmium transporter activity", "id": "GO:0015434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015434", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" } ], "pmid": "" }, { "name": "xenobiotic transport", "id": "GO:0042908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042908", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53049-1", "start_pos": "661", "end_pos": "661", "site_lbl": "Asn661", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 661, "start_aa": "Asn", "end_pos": 661, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn661", "evidence": [ { "id": "P53049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53049#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "759", "end_pos": "759", "site_lbl": "Asn759", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 759, "start_aa": "Asn", "end_pos": 759, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn759", "evidence": [ { "id": "P53049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53049#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "799", "end_pos": "799", "site_lbl": "Asn799", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 799, "start_aa": "Asn", "end_pos": 799, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn799", "evidence": [ { "id": "P53049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53049#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Thr12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Thr53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Thr569", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "576", "end_pos": "576", "site_lbl": "Ser576", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Thr577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "848", "end_pos": "848", "site_lbl": "Thr848", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "851", "end_pos": "851", "site_lbl": "Ser851", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "853", "end_pos": "853", "site_lbl": "Thr853", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "856", "end_pos": "856", "site_lbl": "Ser856", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003513", "url": "https://www.yeastgenome.org/locus/S000003513" }, { "database": "iPTMnet", "id": "P53049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53049" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "1392", "end_pos": "1392", "site_lbl": "Glu1392", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "Abolishes ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" }, { "database": "PubMed", "id": "17950691", "url": "https://glygen.org/publication/PubMed/17950691" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "1423", "end_pos": "1423", "site_lbl": "His1423", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "R", "comment": "Abolishes ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" }, { "database": "PubMed", "id": "17950691", "url": "https://glygen.org/publication/PubMed/17950691" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "670", "end_pos": "670", "site_lbl": "Phe670", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "", "comment": "Causes the protein to be retained in the endoplasmic reticulum (ER) and degraded via ER-associated degradation.", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" }, { "database": "PubMed", "id": "10082567", "url": "https://glygen.org/publication/PubMed/10082567" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Asp71", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Causes the protein to be retained in the endoplasmic reticulum (ER) and degraded via ER-associated degradation.", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" }, { "database": "PubMed", "id": "12107161", "url": "https://glygen.org/publication/PubMed/12107161" } ] } ] }, { "uniprot_canonical_ac": "P53049-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Glu73", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Causes the protein to be retained in the endoplasmic reticulum (ER) and degraded via ER-associated degradation.", "evidence": [ { "database": "UniProtKB", "id": "P53049", "url": "https://www.uniprot.org/uniprotkb/P53049" }, { "database": "PubMed", "id": "12107161", "url": "https://glygen.org/publication/PubMed/12107161" } ] } ] } ], "record_id": "P53049-1" }, { "uniprot_canonical_ac": "P53051-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 589, "chemical_mass": 68592.0, "gene_names": "IMA1;IMA1", "protein_name": "Oligo-1,6-glucosidase IMA1", "disease": [ { "disease_id": "DOID:9266", "name": "cystinuria", "description": "An amino acid metabolic disorder that involves the formation of cystine stones in the kidneys, ureter, and bladder.", "url": "https://disease-ontology.org/term/DOID:9266", "evidence": [ { "id": "9266", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9266" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "alpha-1,4-glucosidase activity", "id": "GO:0004558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004558", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" } ], "pmid": "" }, { "name": "alpha-amylase activity", "id": "GO:0004556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004556", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" } ], "pmid": "" }, { "name": "oligo-1,6-glucosidase activity", "id": "GO:0004574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004574", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" } ], "pmid": "" }, { "name": "sucrose alpha-glucosidase activity", "id": "GO:0004575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004575", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" } ], "pmid": "" }, { "name": "glucan 1,4-alpha-maltotriohydrolase activity", "id": "GO:0033934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033934", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" } ], "pmid": "" } ], "biological_process": [ { "name": "maltose catabolic process", "id": "GO:0000025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000025", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" } ], "pmid": "" }, { "name": "sucrose catabolic process", "id": "GO:0005987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005987", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" } ], "pmid": "" }, { "name": "disaccharide catabolic process", "id": "GO:0046352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046352", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53051-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Asp215", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" }, { "database": "PubMed", "id": "15291818", "url": "https://glygen.org/publication/PubMed/15291818" } ] } ] }, { "uniprot_canonical_ac": "P53051-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Val216", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "T", "comment": "Can also hydrolyze maltose.", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" }, { "database": "PubMed", "id": "15291818", "url": "https://glygen.org/publication/PubMed/15291818" } ] } ] }, { "uniprot_canonical_ac": "P53051-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Gly217", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Does not alter substrate specificity.", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" }, { "database": "PubMed", "id": "15291818", "url": "https://glygen.org/publication/PubMed/15291818" } ] } ] }, { "uniprot_canonical_ac": "P53051-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "G", "comment": "Does not alter substrate specificity.", "evidence": [ { "database": "UniProtKB", "id": "P53051", "url": "https://www.uniprot.org/uniprotkb/P53051" }, { "database": "PubMed", "id": "15291818", "url": "https://glygen.org/publication/PubMed/15291818" } ] } ] } ], "record_id": "P53051-1" }, { "uniprot_canonical_ac": "P53061-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 704, "chemical_mass": 82816.0, "gene_names": "ZIP2;NRC704;ZIP2", "protein_name": "Protein ZIP2", "disease": [], "cellular_component": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" }, { "name": "synaptonemal complex", "id": "GO:0000795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000795", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" } ], "biological_process": [ { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" }, { "name": "synaptonemal complex assembly", "id": "GO:0007130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007130", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" }, { "name": "positive regulation of protein sumoylation", "id": "GO:0033235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033235", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" }, { "name": "homologous recombination", "id": "GO:0035825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035825", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" }, { "name": "regulation of synaptonemal complex assembly", "id": "GO:0090173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090173", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" }, { "name": "DNA secondary structure binding", "id": "GO:0000217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000217", "evidence": [ { "database": "UniProtKB", "id": "P53061", "url": "https://www.uniprot.org/uniprotkb/P53061" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53061-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53061", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53061" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P53061-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Thr394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53061", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53061" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] } ], "record_id": "P53061-1" }, { "uniprot_canonical_ac": "P53063-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 387, "chemical_mass": 44510.0, "gene_names": "RAI1;NRE387;RAI1", "protein_name": "Decapping nuclease RAI1", "disease": [], "molecular_function": [ { "name": "mRNA 5'-diphosphatase activity", "id": "GO:0034353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034353", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "phosphodiesterase decapping endonuclease activity", "id": "GO:1990174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990174", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "RNA NAD+-cap (NAD+-forming) hydrolase activity", "id": "GO:0110152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110152", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000448", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "deadenylation-independent decapping of nuclear-transcribed mRNA", "id": "GO:0031087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031087", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000466", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "NAD-cap decapping", "id": "GO:0110155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110155", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "positive regulation of termination of RNA polymerase II transcription", "id": "GO:1904595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904595", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription, poly(A)-coupled", "id": "GO:0030846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030846", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53063-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003215", "url": "https://www.yeastgenome.org/locus/S000003215" }, { "database": "iPTMnet", "id": "P53063", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53063" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53063-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003215", "url": "https://www.yeastgenome.org/locus/S000003215" }, { "database": "iPTMnet", "id": "P53063", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53063" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53063-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53063", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53063" }, { "database": "SGD", "id": "S000003215", "url": "https://www.yeastgenome.org/locus/S000003215" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53063-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Ser361", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003215", "url": "https://www.yeastgenome.org/locus/S000003215" }, { "database": "iPTMnet", "id": "P53063", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53063" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53063-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003215", "url": "https://www.yeastgenome.org/locus/S000003215" }, { "database": "iPTMnet", "id": "P53063", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53063" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53063-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Glu221", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Abolishes the decapping activity.", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" }, { "database": "PubMed", "id": "20802481", "url": "https://glygen.org/publication/PubMed/20802481" } ] } ] }, { "uniprot_canonical_ac": "P53063-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Asp223", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes the decapping activity.", "evidence": [ { "database": "UniProtKB", "id": "P53063", "url": "https://www.uniprot.org/uniprotkb/P53063" }, { "database": "PubMed", "id": "20802481", "url": "https://glygen.org/publication/PubMed/20802481" } ] } ] } ], "record_id": "P53063-1" }, { "uniprot_canonical_ac": "P53076-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 958, "chemical_mass": 108179.0, "gene_names": "VID30;GID1;VID30", "protein_name": "GID complex subunit 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" } ], "pmid": "" }, { "name": "negative regulation of gluconeogenesis", "id": "GO:0045721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045721", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" } ], "pmid": "" }, { "name": "regulation of nitrogen utilization", "id": "GO:0006808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006808", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53076-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Ser288", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 288, "start_aa": "Ser", "end_pos": 288, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser288", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53076", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53076" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Ser289", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 289, "start_aa": "Ser", "end_pos": 289, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser289", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53076", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53076" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Ser303", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 303, "start_aa": "Ser", "end_pos": 303, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser303", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53076", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53076" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Ser305", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 305, "start_aa": "Ser", "end_pos": 305, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser305", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53076", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53076" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 307, "start_aa": "Ser", "end_pos": 307, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser307", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53076", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53076" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Ser228", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Ser248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53076", "url": "https://www.uniprot.org/uniprotkb/P53076" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Ser279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "366", "end_pos": "366", "site_lbl": "Ser366", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Thr375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Ser376", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "445", "end_pos": "445", "site_lbl": "Ser445", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "453", "end_pos": "453", "site_lbl": "Ser453", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "467", "end_pos": "467", "site_lbl": "Ser467", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Thr468", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Ser469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Thr471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53076-1", "start_pos": "920", "end_pos": "920", "site_lbl": "Ser920", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003196", "url": "https://www.yeastgenome.org/locus/S000003196" }, { "database": "iPTMnet", "id": "P53076", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53076" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53076-1" }, { "uniprot_canonical_ac": "P53079-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53079", "url": "https://www.uniprot.org/uniprotkb/P53079" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 417, "chemical_mass": 48337.0, "gene_names": "COG1;COD3;COG1;LDB11;SEC36;TFI1", "protein_name": "Conserved oligomeric Golgi complex subunit 1", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P53079", "url": "https://www.uniprot.org/uniprotkb/P53079" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "P53079", "url": "https://www.uniprot.org/uniprotkb/P53079" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P53079", "url": "https://www.uniprot.org/uniprotkb/P53079" } ], "pmid": "" } ], "biological_process": [ { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "P53079", "url": "https://www.uniprot.org/uniprotkb/P53079" } ], "pmid": "" }, { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "P53079", "url": "https://www.uniprot.org/uniprotkb/P53079" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P53079", "url": "https://www.uniprot.org/uniprotkb/P53079" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P53079", "url": "https://www.uniprot.org/uniprotkb/P53079" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53079-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Thr303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003191", "url": "https://www.yeastgenome.org/locus/S000003191" }, { "database": "iPTMnet", "id": "P53079", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53079" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53079-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Ser305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53079", "url": "https://www.uniprot.org/uniprotkb/P53079" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53079", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53079" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003191", "url": "https://www.yeastgenome.org/locus/S000003191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53079-1" }, { "uniprot_canonical_ac": "P53082-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 120, "chemical_mass": 14102.0, "gene_names": "BOL2;AIM15;BOL2;FRA2", "protein_name": "BolA-like protein 2", "disease": [], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "pmid": "" }, { "name": "cellular response to iron ion", "id": "GO:0071281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071281", "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "pmid": "" } ], "molecular_function": [ { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "P53082", "url": "https://www.uniprot.org/uniprotkb/P53082" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53082-1" }, { "uniprot_canonical_ac": "P53083-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 459, "chemical_mass": 51990.0, "gene_names": "MDM34;MDM34;MMM2", "protein_name": "Mitochondrial distribution and morphology protein 34", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "pmid": "" }, { "name": "ERMES complex", "id": "GO:0032865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032865", "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "pmid": "" }, { "name": "mitochondrion-endoplasmic reticulum membrane tethering", "id": "GO:1990456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990456", "evidence": [ { "database": "UniProtKB", "id": "P53083", "url": "https://www.uniprot.org/uniprotkb/P53083" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53083-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003187", "url": "https://www.yeastgenome.org/locus/S000003187" }, { "database": "iPTMnet", "id": "P53083", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53083" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53083-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003187", "url": "https://www.yeastgenome.org/locus/S000003187" }, { "database": "iPTMnet", "id": "P53083", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53083" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53083-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003187", "url": "https://www.yeastgenome.org/locus/S000003187" }, { "database": "iPTMnet", "id": "P53083", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53083" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53083-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Ser341", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003187", "url": "https://www.yeastgenome.org/locus/S000003187" }, { "database": "iPTMnet", "id": "P53083", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53083" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53083-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Thr388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003187", "url": "https://www.yeastgenome.org/locus/S000003187" }, { "database": "iPTMnet", "id": "P53083", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53083" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53083-1", "start_pos": "454", "end_pos": "454", "site_lbl": "Ser454", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003187", "url": "https://www.yeastgenome.org/locus/S000003187" }, { "database": "iPTMnet", "id": "P53083", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53083" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53083-1" }, { "uniprot_canonical_ac": "P53086-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 805, "chemical_mass": 91090.0, "gene_names": "KIP3;KIP3", "protein_name": "Kinesin-like protein KIP3", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic chromosome movement towards spindle pole", "id": "GO:0007079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007079", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "microtubule plus-end directed mitotic chromosome migration", "id": "GO:0099606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099606", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "plus-end specific microtubule depolymerization", "id": "GO:0070462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070462", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "microtubule depolymerization", "id": "GO:0007019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007019", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "mitotic spindle disassembly", "id": "GO:0051228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051228", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "negative regulation of microtubule polymerization", "id": "GO:0031115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031115", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "nuclear migration along microtubule", "id": "GO:0030473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030473", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "regulation of mitotic spindle elongation", "id": "GO:0032888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032888", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "meiotic sister chromatid segregation", "id": "GO:0045144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045144", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "tubulin-dependent ATPase activity", "id": "GO:0070463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070463", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "microtubule plus-end", "id": "GO:0035371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "mitotic spindle astral microtubule", "id": "GO:0061673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061673", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "mitotic spindle midzone", "id": "GO:1990023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990023", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" }, { "name": "nuclear microtubule", "id": "GO:0005880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005880", "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprotkb/P53086" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53086-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Ser299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003184", "url": "https://www.yeastgenome.org/locus/S000003184" }, { "database": "iPTMnet", "id": "P53086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53086" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53086-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Ser455", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003184", "url": "https://www.yeastgenome.org/locus/S000003184" }, { "database": "iPTMnet", "id": "P53086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53086" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53086-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53086" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003184", "url": "https://www.yeastgenome.org/locus/S000003184" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53086-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53086" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003184", "url": "https://www.yeastgenome.org/locus/S000003184" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53086-1", "start_pos": "730", "end_pos": "730", "site_lbl": "Ser730", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003184", "url": "https://www.yeastgenome.org/locus/S000003184" }, { "database": "iPTMnet", "id": "P53086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53086" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53086-1", "start_pos": "792", "end_pos": "792", "site_lbl": "Ser792", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003184", "url": "https://www.yeastgenome.org/locus/S000003184" }, { "database": "iPTMnet", "id": "P53086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53086" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P53086-1" }, { "uniprot_canonical_ac": "P53088-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 359, "chemical_mass": 39987.0, "gene_names": "NCS6;CTU1;NCS6;TUC1;YGL210W-A", "protein_name": "Cytoplasmic tRNA 2-thiolation protein 1", "disease": [], "biological_process": [ { "name": "tRNA wobble position uridine thiolation", "id": "GO:0002143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002143", "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "pmid": "" }, { "name": "tRNA thio-modification", "id": "GO:0034227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034227", "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "pmid": "" }, { "name": "protein urmylation", "id": "GO:0032447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032447", "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "pmid": "" }, { "name": "cytosolic tRNA wobble base thiouridylase complex", "id": "GO:0002144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002144", "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "P53088", "url": "https://www.uniprot.org/uniprotkb/P53088" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53088-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Thr213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003179", "url": "https://www.yeastgenome.org/locus/S000003179" }, { "database": "iPTMnet", "id": "P53088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53088-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Ser215", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003179", "url": "https://www.yeastgenome.org/locus/S000003179" }, { "database": "iPTMnet", "id": "P53088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53088-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003179", "url": "https://www.yeastgenome.org/locus/S000003179" }, { "database": "iPTMnet", "id": "P53088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53088-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53088" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003179", "url": "https://www.yeastgenome.org/locus/S000003179" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53088-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003179", "url": "https://www.yeastgenome.org/locus/S000003179" }, { "database": "iPTMnet", "id": "P53088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53088-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Ser358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003179", "url": "https://www.yeastgenome.org/locus/S000003179" }, { "database": "iPTMnet", "id": "P53088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53088-1" }, { "uniprot_canonical_ac": "P53090-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 500, "chemical_mass": 56178.0, "gene_names": "ARO8;ARO8", "protein_name": "Aromatic/aminoadipate aminotransferase 1", "disease": [], "biological_process": [ { "name": "tyrosine biosynthetic process", "id": "GO:0006571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006571", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "pmid": "" }, { "name": "lysine biosynthetic process via aminoadipic acid", "id": "GO:0019878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019878", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "pmid": "" }, { "name": "L-methionine salvage from methylthioadenosine", "id": "GO:0019509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019509", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "pmid": "" }, { "name": "aromatic amino acid metabolic process", "id": "GO:0009072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009072", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "pmid": "" }, { "name": "aromatic amino acid family catabolic process", "id": "GO:0009074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009074", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "pmid": "" }, { "name": "L-phenylalanine biosynthetic process", "id": "GO:0009094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009094", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "pmid": "" }, { "name": "2-aminoadipate transaminase activity", "id": "GO:0047536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047536", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "pmid": "" }, { "name": "aromatic-amino-acid transaminase activity", "id": "GO:0008793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008793", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53090-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Ser100", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 100, "start_aa": "Ser", "end_pos": 100, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser100", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53090", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53090" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53090", "url": "https://www.uniprot.org/uniprotkb/P53090" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 90, "start_aa": "Ser", "end_pos": 90, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser90", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53090", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53090" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 94, "start_aa": "Ser", "end_pos": 94, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser94", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53090", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53090" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Tyr11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Thr203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Ser271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Ser272", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Ser283", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Thr287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Ser290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Ser320", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Ser426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "442", "end_pos": "442", "site_lbl": "Ser442", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "462", "end_pos": "462", "site_lbl": "Ser462", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Ser477", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "499", "end_pos": "499", "site_lbl": "Ser499", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53090-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003170", "url": "https://www.yeastgenome.org/locus/S000003170" }, { "database": "iPTMnet", "id": "P53090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53090-1" }, { "uniprot_canonical_ac": "P53095-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53095", "url": "https://www.uniprot.org/uniprotkb/P53095" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 428, "chemical_mass": 47828.0, "gene_names": "DSD1;DSD1;G1315", "protein_name": "D-serine dehydratase", "disease": [], "molecular_function": [ { "name": "D-serine ammonia-lyase activity", "id": "GO:0008721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008721", "evidence": [ { "database": "UniProtKB", "id": "P53095", "url": "https://www.uniprot.org/uniprotkb/P53095" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53095", "url": "https://www.uniprot.org/uniprotkb/P53095" } ], "pmid": "" } ], "biological_process": [ { "name": "D-serine catabolic process", "id": "GO:0036088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036088", "evidence": [ { "database": "UniProtKB", "id": "P53095", "url": "https://www.uniprot.org/uniprotkb/P53095" } ], "pmid": "" }, { "name": "D-serine metabolic process", "id": "GO:0070178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070178", "evidence": [ { "database": "UniProtKB", "id": "P53095", "url": "https://www.uniprot.org/uniprotkb/P53095" } ], "pmid": "" }, { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "P53095", "url": "https://www.uniprot.org/uniprotkb/P53095" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53095-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003164", "url": "https://www.yeastgenome.org/locus/S000003164" }, { "database": "iPTMnet", "id": "P53095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53095" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53095-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Ser338", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003164", "url": "https://www.yeastgenome.org/locus/S000003164" }, { "database": "iPTMnet", "id": "P53095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53095" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53095-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003164", "url": "https://www.yeastgenome.org/locus/S000003164" }, { "database": "iPTMnet", "id": "P53095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53095" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53095-1" }, { "uniprot_canonical_ac": "P53101-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53101", "url": "https://www.uniprot.org/uniprotkb/P53101" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 465, "chemical_mass": 51828.0, "gene_names": "STR3;G1601;STR3", "protein_name": "Cystathionine beta-lyase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53101", "url": "https://www.uniprot.org/uniprotkb/P53101" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53101", "url": "https://www.uniprot.org/uniprotkb/P53101" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P53101", "url": "https://www.uniprot.org/uniprotkb/P53101" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "P53101", "url": "https://www.uniprot.org/uniprotkb/P53101" } ], "pmid": "" }, { "name": "carbon-sulfur lyase activity", "id": "GO:0016846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016846", "evidence": [ { "database": "UniProtKB", "id": "P53101", "url": "https://www.uniprot.org/uniprotkb/P53101" } ], "pmid": "" }, { "name": "cysteine-S-conjugate beta-lyase activity", "id": "GO:0047804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047804", "evidence": [ { "database": "UniProtKB", "id": "P53101", "url": "https://www.uniprot.org/uniprotkb/P53101" } ], "pmid": "" } ], "biological_process": [ { "name": "methionine biosynthetic process", "id": "GO:0009086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009086", "evidence": [ { "database": "UniProtKB", "id": "P53101", "url": "https://www.uniprot.org/uniprotkb/P53101" } ], "pmid": "" }, { "name": "transsulfuration", "id": "GO:0019346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019346", "evidence": [ { "database": "UniProtKB", "id": "P53101", "url": "https://www.uniprot.org/uniprotkb/P53101" } ], "pmid": "" }, { "name": "'de novo' L-methionine biosynthetic process", "id": "GO:0071266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071266", "evidence": [ { "database": "UniProtKB", "id": "P53101", "url": "https://www.uniprot.org/uniprotkb/P53101" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53101-1", "start_pos": "456", "end_pos": "456", "site_lbl": "Ser456", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53101", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53101" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003152", "url": "https://www.yeastgenome.org/locus/S000003152" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53101-1" }, { "uniprot_canonical_ac": "P53108-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53108", "url": "https://www.uniprot.org/uniprotkb/P53108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 310, "chemical_mass": 34843.0, "gene_names": "YIP5;G1832;YIP5", "protein_name": "Protein YIP5", "disease": [], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P53108", "url": "https://www.uniprot.org/uniprotkb/P53108" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P53108", "url": "https://www.uniprot.org/uniprotkb/P53108" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "P53108", "url": "https://www.uniprot.org/uniprotkb/P53108" } ], "pmid": "" } ], "biological_process": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "P53108", "url": "https://www.uniprot.org/uniprotkb/P53108" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53108-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003129", "url": "https://www.yeastgenome.org/locus/S000003129" }, { "database": "iPTMnet", "id": "P53108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53108" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53108-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003129", "url": "https://www.yeastgenome.org/locus/S000003129" }, { "database": "iPTMnet", "id": "P53108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53108" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53108-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Thr54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003129", "url": "https://www.yeastgenome.org/locus/S000003129" }, { "database": "iPTMnet", "id": "P53108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53108" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53108-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003129", "url": "https://www.yeastgenome.org/locus/S000003129" }, { "database": "iPTMnet", "id": "P53108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53108" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53108-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53108", "url": "https://www.uniprot.org/uniprotkb/P53108" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53108" }, { "database": "SGD", "id": "S000003129", "url": "https://www.yeastgenome.org/locus/S000003129" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53108-1" }, { "uniprot_canonical_ac": "P53109-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53109", "url": "https://www.uniprot.org/uniprotkb/P53109" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 570, "chemical_mass": 65840.0, "gene_names": "AIM14;AIM14;G1837;YNO1", "protein_name": "Probable metalloreductase AIM14", "disease": [ { "disease_id": "DOID:0050328", "name": "congenital hypothyroidism", "description": "A hypothyroidism that is present at birth.", "url": "https://disease-ontology.org/term/DOID:0050328", "evidence": [ { "id": "0050328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050328" } ], "weight": 0.0 }, { "disease_id": "DOID:0050338", "name": "primary bacterial infectious disease", "description": "A bacterial infectious disease that results_in infection by bacteria as a result of their presence or activity within the normal, healthy host, and their intrinsic virulence is, in part, a necessary consequence of their need to reproduce and spread.", "url": "https://disease-ontology.org/term/DOID:0050338", "evidence": [ { "id": "0050338", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050338" } ], "weight": 0.0 }, { "disease_id": "DOID:0050855", "name": "renal fibrosis", "description": "A kidney disease that is characterized by progressive detrimental connective tissue deposition of the kidney parenchyma leading to deterioration of renal function.", "url": "https://disease-ontology.org/term/DOID:0050855", "evidence": [ { "id": "0050855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050855" } ], "weight": 0.0 }, { "disease_id": "DOID:0070195", "name": "X-linked chronic granulomatous disease", "description": "A chronic granulomatous disease characterized by X-linked inheritance that has_material_basis_in mutation in the CYBB gene on chromosome Xp21.1-p11.4.", "url": "https://disease-ontology.org/term/DOID:0070195", "evidence": [ { "id": "0070195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070195" } ], "weight": 0.0 }, { "disease_id": "DOID:0080547", "name": "metabolic dysfunction-associated steatohepatitis", "description": "A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.", "url": "https://disease-ontology.org/term/DOID:0080547", "evidence": [ { "id": "0080547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080547" } ], "weight": 0.0 }, { "disease_id": "DOID:0112000", "name": "immunodeficiency 34", "description": "A phagocyte bactericidal dysfunction characterized by impaired respiratory burst in all types of phagocytes and increased susceptibility to infection by poorly virulent mycobacteria that has_material_basis_in hemizygous mutation in the CYBB gene on chromosome Xp21.1-p11.4.", "url": "https://disease-ontology.org/term/DOID:0112000", "evidence": [ { "id": "0112000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112000" } ], "weight": 0.0 }, { "disease_id": "DOID:0112189", "name": "thyroid dyshormonogenesis 6", "description": "A familial thyroid dyshormonogenesis that has_material_basis_in homozygous or compound heterozygous mutation in DUOX2 on chromosome 15q21.1.", "url": "https://disease-ontology.org/term/DOID:0112189", "evidence": [ { "id": "0112189", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112189" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:1498", "name": "cholera", "description": "A primary bacterial infectious disease that is described as an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae, which is characterized by profuse watery diarrhea, vomiting, leg cramps, circulatory collapse and shock.", "url": "https://disease-ontology.org/term/DOID:1498", "evidence": [ { "id": "1498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1498" } ], "weight": 0.0 }, { "disease_id": "DOID:3265", "name": "chronic granulomatous disease", "description": "A phagocyte bactericidal dysfunction characterized by an inability to resist repeated infectious diseases and a tendency to develop chronic inflammation. Life-threatening recurrent fungal and bacterial infections affecting the skin, lungs, liver, lymph nodes, and bones may occur along with swollen areas of inflamed tissues known as granulomas that can be widely distributed.", "url": "https://disease-ontology.org/term/DOID:3265", "evidence": [ { "id": "3265", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3265" } ], "weight": 0.0 }, { "disease_id": "DOID:446", "name": "primary hyperaldosteronism", "description": "An adrenal gland hyperfunction disease that results in the overproduction of aldosterone by the adrenal glands.", "url": "https://disease-ontology.org/term/DOID:446", "evidence": [ { "id": "446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:446" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 }, { "disease_id": "DOID:9281", "name": "phenylketonuria", "description": "An amino acid metabolic disorder that is characterized by a mutation in the gene for the hepatic enzyme phenylalanine hydroxylase (PAH), rendering it nonfunctional.", "url": "https://disease-ontology.org/term/DOID:9281", "evidence": [ { "id": "9281", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9281" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53109", "url": "https://www.uniprot.org/uniprotkb/P53109" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53109", "url": "https://www.uniprot.org/uniprotkb/P53109" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "P53109", "url": "https://www.uniprot.org/uniprotkb/P53109" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "P53109", "url": "https://www.uniprot.org/uniprotkb/P53109" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "P53109", "url": "https://www.uniprot.org/uniprotkb/P53109" } ], "pmid": "" }, { "name": "iron import into cell", "id": "GO:0033212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033212", "evidence": [ { "database": "UniProtKB", "id": "P53109", "url": "https://www.uniprot.org/uniprotkb/P53109" } ], "pmid": "" } ], "molecular_function": [ { "name": "ferric-chelate reductase activity", "id": "GO:0000293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000293", "evidence": [ { "database": "UniProtKB", "id": "P53109", "url": "https://www.uniprot.org/uniprotkb/P53109" } ], "pmid": "" }, { "name": "superoxide-generating NAD(P)H oxidase activity", "id": "GO:0016175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016175", "evidence": [ { "database": "UniProtKB", "id": "P53109", "url": "https://www.uniprot.org/uniprotkb/P53109" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53109-1", "start_pos": "464", "end_pos": "464", "site_lbl": "Ser464", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003128", "url": "https://www.yeastgenome.org/locus/S000003128" }, { "database": "iPTMnet", "id": "P53109", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53109" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53109-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Ser479", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003128", "url": "https://www.yeastgenome.org/locus/S000003128" }, { "database": "iPTMnet", "id": "P53109", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53109" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53109-1" }, { "uniprot_canonical_ac": "P53115-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1489, "chemical_mass": 171455.0, "gene_names": "INO80;G1880;INO80", "protein_name": "Chromatin-remodeling ATPase INO80", "disease": [], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "regulation of TOR signaling", "id": "GO:0032006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032006", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "cellular response to stress", "id": "GO:0033554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033554", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "telomere maintenance via recombination", "id": "GO:0000722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000722", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "Ino80 complex", "id": "GO:0031011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53115-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 2, "start_aa": "Ser", "end_pos": 2, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53115", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53115" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "1466", "end_pos": "1466", "site_lbl": "Ser1466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "1469", "end_pos": "1469", "site_lbl": "Thr1469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "1473", "end_pos": "1473", "site_lbl": "Ser1473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "1475", "end_pos": "1475", "site_lbl": "Ser1475", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "1477", "end_pos": "1477", "site_lbl": "Ser1477", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Ser302", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Ser304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "422", "end_pos": "422", "site_lbl": "Ser422", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "497", "end_pos": "497", "site_lbl": "Ser497", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "508", "end_pos": "508", "site_lbl": "Ser508", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Ser610", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "614", "end_pos": "614", "site_lbl": "Ser614", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "616", "end_pos": "616", "site_lbl": "Ser616", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53115" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000003118", "url": "https://www.yeastgenome.org/locus/S000003118" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53115-1", "start_pos": "737", "end_pos": "737", "site_lbl": "Lys737", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Reduced ATPase activity of the INO80 complex.", "evidence": [ { "database": "UniProtKB", "id": "P53115", "url": "https://www.uniprot.org/uniprotkb/P53115" }, { "database": "PubMed", "id": "10952318", "url": "https://glygen.org/publication/PubMed/10952318" } ] } ] } ], "record_id": "P53115-1" }, { "uniprot_canonical_ac": "P53118-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53118", "url": "https://www.uniprot.org/uniprotkb/P53118" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 685, "chemical_mass": 78142.0, "gene_names": "ROG1;ROG1", "protein_name": "Putative lipase ROG1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53118", "url": "https://www.uniprot.org/uniprotkb/P53118" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53118", "url": "https://www.uniprot.org/uniprotkb/P53118" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "P53118", "url": "https://www.uniprot.org/uniprotkb/P53118" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "P53118", "url": "https://www.uniprot.org/uniprotkb/P53118" } ], "pmid": "" } ], "molecular_function": [ { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "P53118", "url": "https://www.uniprot.org/uniprotkb/P53118" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53118-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003112", "url": "https://www.yeastgenome.org/locus/S000003112" }, { "database": "iPTMnet", "id": "P53118", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53118" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53118-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003112", "url": "https://www.yeastgenome.org/locus/S000003112" }, { "database": "iPTMnet", "id": "P53118", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53118" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53118-1", "start_pos": "603", "end_pos": "603", "site_lbl": "Ser603", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003112", "url": "https://www.yeastgenome.org/locus/S000003112" }, { "database": "iPTMnet", "id": "P53118", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53118" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53118-1" }, { "uniprot_canonical_ac": "P53119-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 910, "chemical_mass": 105566.0, "gene_names": "HUL5;HUL5", "protein_name": "E3 ubiquitin-protein ligase HUL5", "disease": [ { "disease_id": "DOID:0111456", "name": "Kaufman oculocerebrofacial syndrome", "description": "A syndromic intellectual disability characterized by developmental delay, growth retardation with a small head circumference, facial dysmorphisms, and low cholesterol levels that has_material_basis_in homozygous or compound heterozygous mutation in the UBE3B gene on chromosome 12q24.11.", "url": "https://disease-ontology.org/term/DOID:0111456", "evidence": [ { "id": "0111456", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111456" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" }, { "name": "cellular response to stress", "id": "GO:0033554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033554", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" }, { "name": "free ubiquitin chain polymerization", "id": "GO:0010994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010994", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" }, { "name": "cytoplasm protein quality control by the ubiquitin-proteasome system", "id": "GO:0071629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071629", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" }, { "name": "ubiquitin-ubiquitin ligase activity", "id": "GO:0034450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034450", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53119-1", "start_pos": "411", "end_pos": "411", "site_lbl": "Ser411", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53119" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53119-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Ser463", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003109", "url": "https://www.yeastgenome.org/locus/S000003109" }, { "database": "iPTMnet", "id": "P53119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53119" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53119-1", "start_pos": "877", "end_pos": "877", "site_lbl": "Thr877", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003109", "url": "https://www.yeastgenome.org/locus/S000003109" }, { "database": "iPTMnet", "id": "P53119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53119" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53119-1", "start_pos": "878", "end_pos": "878", "site_lbl": "Cys878", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Abolishes E3 ubiquitin-protein ligase activity.", "evidence": [ { "database": "UniProtKB", "id": "P53119", "url": "https://www.uniprot.org/uniprotkb/P53119" }, { "database": "PubMed", "id": "20008553", "url": "https://glygen.org/publication/PubMed/20008553" }, { "database": "PubMed", "id": "21983566", "url": "https://glygen.org/publication/PubMed/21983566" }, { "database": "PubMed", "id": "17190603", "url": "https://glygen.org/publication/PubMed/17190603" } ] } ] } ], "record_id": "P53119-1" }, { "uniprot_canonical_ac": "P53127-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1403, "chemical_mass": 163203.0, "gene_names": "SNT2;G2850;SNT2", "protein_name": "E3 ubiquitin-protein ligase SNT2", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "Lid2 complex", "id": "GO:0048189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048189", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "Snt2C complex", "id": "GO:0070211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070211", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" }, { "name": "histone catabolic process", "id": "GO:0036205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036205", "evidence": [ { "database": "UniProtKB", "id": "P53127", "url": "https://www.uniprot.org/uniprotkb/P53127" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53127-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Ser468", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53127" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003099", "url": "https://www.yeastgenome.org/locus/S000003099" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53127-1", "start_pos": "641", "end_pos": "641", "site_lbl": "Ser641", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53127" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003099", "url": "https://www.yeastgenome.org/locus/S000003099" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53127-1", "start_pos": "695", "end_pos": "695", "site_lbl": "Ser695", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53127" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P53127-1", "start_pos": "698", "end_pos": "698", "site_lbl": "Ser698", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53127" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003099", "url": "https://www.yeastgenome.org/locus/S000003099" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53127-1", "start_pos": "763", "end_pos": "763", "site_lbl": "Ser763", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003099", "url": "https://www.yeastgenome.org/locus/S000003099" }, { "database": "iPTMnet", "id": "P53127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53127" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53127-1", "start_pos": "870", "end_pos": "870", "site_lbl": "Ser870", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003099", "url": "https://www.yeastgenome.org/locus/S000003099" }, { "database": "iPTMnet", "id": "P53127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53127" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53127-1" }, { "uniprot_canonical_ac": "P53129-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 644, "chemical_mass": 73478.0, "gene_names": "MON1;AUT12;G2889;MON1", "protein_name": "Vacuolar fusion protein MON1", "disease": [], "biological_process": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "vesicle docking", "id": "GO:0048278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048278", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "protein targeting to vacuolar membrane", "id": "GO:0044395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044395", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-5-phosphate binding", "id": "GO:0010314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010314", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "guanyl nucleotide exchange factor inhibitor activity", "id": "GO:1990624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990624", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "multivesicular body membrane", "id": "GO:0032585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032585", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" }, { "name": "Mon1-Ccz1 complex", "id": "GO:0035658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035658", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53129-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Ser62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Thr74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53129", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53129" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003092", "url": "https://www.yeastgenome.org/locus/S000003092" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53129-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Trp406", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Disruption of YPT10 binding resulting in reduced Rab5 homolog-dependent GEF activity toward YPT7 on membranes but not in solution.", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" }, { "database": "PubMed", "id": "37463208", "url": "https://glygen.org/publication/PubMed/37463208" } ] }, { "sequence_org": "W", "sequence_mut": "K", "comment": "Cellular growth deficiency, possibly due to disruption of MON1-CCZ1 complex recruitment by RAB5 proteins.", "evidence": [ { "database": "UniProtKB", "id": "P53129", "url": "https://www.uniprot.org/uniprotkb/P53129" }, { "database": "PubMed", "id": "37463208", "url": "https://glygen.org/publication/PubMed/37463208" } ] } ] } ], "record_id": "P53129-1" }, { "uniprot_canonical_ac": "P53140-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 646, "chemical_mass": 74596.0, "gene_names": "RMD9;G3075;RMD9", "protein_name": "RNA-binding protein RMD9, mitochondrial", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" }, { "name": "3'-UTR-mediated mRNA stabilization", "id": "GO:0070935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070935", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" }, { "name": "aerobic respiration", "id": "GO:0009060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009060", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" }, { "name": "regulation of mitochondrial transcription", "id": "GO:1903108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903108", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" }, { "name": "mitochondrial mRNA processing", "id": "GO:0090615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090615", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53140-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Val363", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "I", "comment": "Causes respiratory deficiency in absence of RSM28.", "evidence": [ { "database": "UniProtKB", "id": "P53140", "url": "https://www.uniprot.org/uniprotkb/P53140" }, { "database": "PubMed", "id": "17194786", "url": "https://glygen.org/publication/PubMed/17194786" } ] } ] } ], "record_id": "P53140-1" }, { "uniprot_canonical_ac": "P53145-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 640, "chemical_mass": 72728.0, "gene_names": "LSG1;KRE35;LSG1", "protein_name": "Large subunit GTPase 1", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "pmid": "" }, { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53145-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Thr367", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 367, "start_aa": "Thr", "end_pos": 367, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr367", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003067", "url": "https://www.yeastgenome.org/locus/S000003067" }, { "database": "iPTMnet", "id": "P53145", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53145" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53145", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53145" }, { "database": "SGD", "id": "S000003067", "url": "https://www.yeastgenome.org/locus/S000003067" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003067", "url": "https://www.yeastgenome.org/locus/S000003067" }, { "database": "iPTMnet", "id": "P53145", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53145" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Thr109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003067", "url": "https://www.yeastgenome.org/locus/S000003067" }, { "database": "iPTMnet", "id": "P53145", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53145" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003067", "url": "https://www.yeastgenome.org/locus/S000003067" }, { "database": "iPTMnet", "id": "P53145", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53145" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "576", "end_pos": "576", "site_lbl": "Thr576", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53145", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53145" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "607", "end_pos": "607", "site_lbl": "Thr607", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53145", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53145" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003067", "url": "https://www.yeastgenome.org/locus/S000003067" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Ser632", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53145", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53145" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003067", "url": "https://www.yeastgenome.org/locus/S000003067" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003067", "url": "https://www.yeastgenome.org/locus/S000003067" }, { "database": "iPTMnet", "id": "P53145", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53145" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Thr69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003067", "url": "https://www.yeastgenome.org/locus/S000003067" }, { "database": "iPTMnet", "id": "P53145", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53145" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ile204", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "T", "comment": "Impairs the nuclear export of 60S ribosomal subunit in cytoplasm.", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" }, { "database": "PubMed", "id": "15660131", "url": "https://glygen.org/publication/PubMed/15660131" } ] } ] }, { "uniprot_canonical_ac": "P53145-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Lys349", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "T", "comment": "Dominant negative mutant; prevents the nuclear export of 60S ribosomal subunit in cytoplasm.", "evidence": [ { "database": "UniProtKB", "id": "P53145", "url": "https://www.uniprot.org/uniprotkb/P53145" }, { "database": "PubMed", "id": "15660131", "url": "https://glygen.org/publication/PubMed/15660131" } ] } ] } ], "record_id": "P53145-1" }, { "uniprot_canonical_ac": "P53148-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 917, "chemical_mass": 104826.0, "gene_names": "SPC105;KNL1;SPC105", "protein_name": "Outer kinetochore KNL1 complex subunit SPC105", "disease": [], "biological_process": [ { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" }, { "name": "homologous chromosome orientation in meiotic metaphase I", "id": "GO:0031619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031619", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" }, { "name": "protein localization to kinetochore", "id": "GO:0034501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034501", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" }, { "name": "sister chromatid biorientation", "id": "GO:0031134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031134", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" }, { "name": "mitotic sister chromatid biorientation", "id": "GO:1990758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990758", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" }, { "name": "positive regulation of meiosis I spindle assembly checkpoint", "id": "GO:1905326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905326", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" }, { "name": "Knl1/Spc105 complex", "id": "GO:0180019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180019", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53148-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Thr149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" }, { "database": "PRO", "id": "P53148", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P53148" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "22521787", "url": "https://glygen.org/publication/PubMed/22521787" }, { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Thr155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Thr172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" }, { "database": "PRO", "id": "P53148", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P53148" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "22521787", "url": "https://glygen.org/publication/PubMed/22521787" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Thr235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" }, { "database": "PRO", "id": "P53148", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P53148" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "22521787", "url": "https://glygen.org/publication/PubMed/22521787" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Ser258", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Ser262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Ser329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Tyr350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Thr355", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Thr356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "380", "end_pos": "380", "site_lbl": "Ser380", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Thr383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Ser385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "414", "end_pos": "414", "site_lbl": "Thr414", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Thr60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53148", "url": "https://www.uniprot.org/uniprotkb/P53148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53148-1", "start_pos": "886", "end_pos": "886", "site_lbl": "Ser886", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003061", "url": "https://www.yeastgenome.org/locus/S000003061" }, { "database": "iPTMnet", "id": "P53148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53148" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53148-1" }, { "uniprot_canonical_ac": "P53152-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 137, "chemical_mass": 15545.0, "gene_names": "MMS2;MMS2", "protein_name": "Ubiquitin-conjugating enzyme variant MMS2", "disease": [], "cellular_component": [ { "name": "ubiquitin conjugating enzyme complex", "id": "GO:0031371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031371", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "pmid": "" } ], "biological_process": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "pmid": "" }, { "name": "free ubiquitin chain polymerization", "id": "GO:0010994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010994", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "pmid": "" }, { "name": "DNA damage tolerance", "id": "GO:0006301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006301", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "pmid": "" }, { "name": "protein targeting to vacuolar membrane", "id": "GO:0044395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044395", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53152-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003055", "url": "https://www.yeastgenome.org/locus/S000003055" }, { "database": "iPTMnet", "id": "P53152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53152" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53152-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003055", "url": "https://www.yeastgenome.org/locus/S000003055" }, { "database": "iPTMnet", "id": "P53152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53152" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53152-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53152" }, { "database": "SGD", "id": "S000003055", "url": "https://www.yeastgenome.org/locus/S000003055" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53152-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Phe8", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Strongly reduces UBC13 binding and interferes with error-free DNA repair.", "evidence": [ { "database": "UniProtKB", "id": "P53152", "url": "https://www.uniprot.org/uniprotkb/P53152" }, { "database": "PubMed", "id": "11440714", "url": "https://glygen.org/publication/PubMed/11440714" } ] } ] } ], "record_id": "P53152-1" }, { "uniprot_canonical_ac": "P53153-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53153", "url": "https://www.uniprot.org/uniprotkb/P53153" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 274, "chemical_mass": 32112.0, "gene_names": "LCL3;LCL3", "protein_name": "Probable endonuclease LCL3", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53153", "url": "https://www.uniprot.org/uniprotkb/P53153" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P53153", "url": "https://www.uniprot.org/uniprotkb/P53153" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "P53153", "url": "https://www.uniprot.org/uniprotkb/P53153" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53153", "url": "https://www.uniprot.org/uniprotkb/P53153" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "P53153", "url": "https://www.uniprot.org/uniprotkb/P53153" } ], "pmid": "" } ], "biological_process": [ { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "P53153", "url": "https://www.uniprot.org/uniprotkb/P53153" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53153-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Thr266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53153", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53153" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P53153-1" }, { "uniprot_canonical_ac": "P53154-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53154", "url": "https://www.uniprot.org/uniprotkb/P53154" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 560, "chemical_mass": 65340.0, "gene_names": "GUP1;GUP1", "protein_name": "Membrane-bound O-acyltransferase GUP1", "disease": [ { "disease_id": "DOID:0060644", "name": "chondrodysplasia-pseudohermaphroditism syndrome", "description": "A syndrome characterized by the clinical features of 46,XY complete gonadal dysgenesis in association with severe dwarfism with generalized chondrodysplasia.", "url": "https://disease-ontology.org/term/DOID:0060644", "evidence": [ { "id": "0060644", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060644" } ], "weight": 0.0 } ], "biological_process": [ { "name": "glycerol catabolic process", "id": "GO:0019563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019563", "evidence": [ { "database": "UniProtKB", "id": "P53154", "url": "https://www.uniprot.org/uniprotkb/P53154" } ], "pmid": "" }, { "name": "glycerol transmembrane transport", "id": "GO:0015793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015793", "evidence": [ { "database": "UniProtKB", "id": "P53154", "url": "https://www.uniprot.org/uniprotkb/P53154" } ], "pmid": "" }, { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "P53154", "url": "https://www.uniprot.org/uniprotkb/P53154" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53154", "url": "https://www.uniprot.org/uniprotkb/P53154" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53154", "url": "https://www.uniprot.org/uniprotkb/P53154" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "P53154", "url": "https://www.uniprot.org/uniprotkb/P53154" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53154", "url": "https://www.uniprot.org/uniprotkb/P53154" } ], "pmid": "" } ], "molecular_function": [ { "name": "O-acyltransferase activity", "id": "GO:0008374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008374", "evidence": [ { "database": "UniProtKB", "id": "P53154", "url": "https://www.uniprot.org/uniprotkb/P53154" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53154-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53154", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53154" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P53154-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Ser518", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003052", "url": "https://www.yeastgenome.org/locus/S000003052" }, { "database": "iPTMnet", "id": "P53154", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53154" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53154-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Thr523", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003052", "url": "https://www.yeastgenome.org/locus/S000003052" }, { "database": "iPTMnet", "id": "P53154", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53154" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53154-1", "start_pos": "525", "end_pos": "525", "site_lbl": "Ser525", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003052", "url": "https://www.yeastgenome.org/locus/S000003052" }, { "database": "iPTMnet", "id": "P53154", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53154" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53154-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53154", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53154" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003052", "url": "https://www.yeastgenome.org/locus/S000003052" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53154-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Tyr95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53154", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53154" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P53154-1", "start_pos": "447", "end_pos": "447", "site_lbl": "His447", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Deficient in GPI anchor remodeling.", "evidence": [ { "database": "UniProtKB", "id": "P53154", "url": "https://www.uniprot.org/uniprotkb/P53154" }, { "database": "PubMed", "id": "16597698", "url": "https://glygen.org/publication/PubMed/16597698" } ] } ] } ], "record_id": "P53154-1" }, { "uniprot_canonical_ac": "P53157-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53157", "url": "https://www.uniprot.org/uniprotkb/P53157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 130, "chemical_mass": 14995.0, "gene_names": "MPC1;FMP37;MPC1", "protein_name": "Mitochondrial pyruvate carrier 1", "disease": [ { "disease_id": "DOID:0080363", "name": "mitochondrial pyruvate carrier deficiency", "description": "A mitochondrial metabolism disease that is characterized by delayed psychomotor development and lactic acidosis with a normal lactate/pyruvate ratio resulting from impaired mitochondrial pyruvate oxidation and has_material_basis_in homozygous mutation in the BRP44L gene on chromosome 6q27.", "url": "https://disease-ontology.org/term/DOID:0080363", "evidence": [ { "id": "0080363", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080363" } ], "weight": 0.0 }, { "disease_id": "DOID:10155", "name": "intestinal cancer", "description": "A gastrointestinal system cancer that is located_in the intestine.", "url": "https://disease-ontology.org/term/DOID:10155", "evidence": [ { "id": "10155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10155" } ], "weight": 0.0 }, { "disease_id": "DOID:700", "name": "mitochondrial metabolism disease", "description": "An inherited metabolic disorder that involves mitochondrial metabolism dysfunction.", "url": "https://disease-ontology.org/term/DOID:700", "evidence": [ { "id": "700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:700" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53157", "url": "https://www.uniprot.org/uniprotkb/P53157" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P53157", "url": "https://www.uniprot.org/uniprotkb/P53157" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P53157", "url": "https://www.uniprot.org/uniprotkb/P53157" } ], "pmid": "" }, { "name": "mitochondrial pyruvate carrier complex", "id": "GO:7770001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:7770001", "evidence": [ { "database": "UniProtKB", "id": "P53157", "url": "https://www.uniprot.org/uniprotkb/P53157" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyruvate transmembrane transporter activity", "id": "GO:0050833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050833", "evidence": [ { "database": "UniProtKB", "id": "P53157", "url": "https://www.uniprot.org/uniprotkb/P53157" } ], "pmid": "" } ], "biological_process": [ { "name": "pyruvate import into mitochondria", "id": "GO:0006850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006850", "evidence": [ { "database": "UniProtKB", "id": "P53157", "url": "https://www.uniprot.org/uniprotkb/P53157" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53157-1" }, { "uniprot_canonical_ac": "P53159-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 387, "chemical_mass": 44585.0, "gene_names": "MPS2;MMC1;MPS2", "protein_name": "Monopolar spindle protein 2", "disease": [], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" }, { "name": "meiotic nuclear membrane microtubule tethering complex", "id": "GO:0034993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034993", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" } ], "biological_process": [ { "name": "spindle pole body duplication", "id": "GO:0030474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030474", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" }, { "name": "karyogamy", "id": "GO:0000741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000741", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" }, { "name": "protein localization to spindle pole body", "id": "GO:0071988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071988", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" }, { "name": "mitotic spindle pole body localization", "id": "GO:1990608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990608", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" }, { "name": "meiotic telomere tethering at nuclear periphery", "id": "GO:0044821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044821", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytoskeleton-nuclear membrane anchor activity", "id": "GO:0140444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140444", "evidence": [ { "database": "UniProtKB", "id": "P53159", "url": "https://www.uniprot.org/uniprotkb/P53159" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53159-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Thr134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53159" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53159-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Ser140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003043", "url": "https://www.yeastgenome.org/locus/S000003043" }, { "database": "iPTMnet", "id": "P53159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53159" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53159-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Thr141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53159" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003043", "url": "https://www.yeastgenome.org/locus/S000003043" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53159-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53159" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003043", "url": "https://www.yeastgenome.org/locus/S000003043" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53159-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Ser228", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003043", "url": "https://www.yeastgenome.org/locus/S000003043" }, { "database": "iPTMnet", "id": "P53159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53159" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53159-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Ser232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003043", "url": "https://www.yeastgenome.org/locus/S000003043" }, { "database": "iPTMnet", "id": "P53159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53159" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53159-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Tyr27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53159" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003043", "url": "https://www.yeastgenome.org/locus/S000003043" } ] } ] } ], "record_id": "P53159-1" }, { "uniprot_canonical_ac": "P53163-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53163", "url": "https://www.uniprot.org/uniprotkb/P53163" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 194, "chemical_mass": 20650.0, "gene_names": "MNP1;MNP1;MRPL12;bL12m", "protein_name": "Large ribosomal subunit protein bL12m", "disease": [ { "disease_id": "DOID:0112113", "name": "combined oxidative phosphorylation deficiency 45", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the MRPL12 gene on chromosome 17q25.3.", "url": "https://disease-ontology.org/term/DOID:0112113", "evidence": [ { "id": "0112113", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112113" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "P53163", "url": "https://www.uniprot.org/uniprotkb/P53163" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53163", "url": "https://www.uniprot.org/uniprotkb/P53163" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P53163", "url": "https://www.uniprot.org/uniprotkb/P53163" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "P53163", "url": "https://www.uniprot.org/uniprotkb/P53163" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P53163", "url": "https://www.uniprot.org/uniprotkb/P53163" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P53163", "url": "https://www.uniprot.org/uniprotkb/P53163" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P53163", "url": "https://www.uniprot.org/uniprotkb/P53163" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "P53163", "url": "https://www.uniprot.org/uniprotkb/P53163" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53163-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Thr20", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 20, "start_aa": "Thr", "end_pos": 20, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr20", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P53163-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Asn34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 34, "start_aa": "Asn", "end_pos": 34, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn34", "evidence": [ { "id": "P53163", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53163#ptm_processing" } ] } ] } ], "record_id": "P53163-1" }, { "uniprot_canonical_ac": "P53164-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 384, "chemical_mass": 43516.0, "gene_names": "NPY1;NPY1", "protein_name": "NAD-capped RNA hydrolase NPY1", "disease": [], "molecular_function": [ { "name": "NAD+ diphosphatase activity", "id": "GO:0000210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000210", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" }, { "name": "NADH pyrophosphatase activity", "id": "GO:0035529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035529", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" }, { "name": "RNA NAD-cap (NMN-forming) hydrolase activity", "id": "GO:0110153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110153", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" } ], "biological_process": [ { "name": "NAD+ catabolic process", "id": "GO:0019677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019677", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" }, { "name": "NAD+ metabolic process", "id": "GO:0019674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019674", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" }, { "name": "NADP+ catabolic process", "id": "GO:0006742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006742", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" }, { "name": "NAD-cap decapping", "id": "GO:0110155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110155", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" }, { "name": "RNA decapping", "id": "GO:0110154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110154", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53164", "url": "https://www.uniprot.org/uniprotkb/P53164" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53164-1" }, { "uniprot_canonical_ac": "P53165-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 657, "chemical_mass": 72878.0, "gene_names": "SGF73;SCA7;SGF73", "protein_name": "SAGA complex subunit SGF73", "disease": [ { "disease_id": "DOID:0050958", "name": "spinocerebellar ataxia 7", "description": "An autosomal dominant cerebellar ataxia that is characterized by ataxia, progressive vision loss, and failure to thrive, has_material_basis_in mutation in the ATXN7 gene.", "url": "https://disease-ontology.org/term/DOID:0050958", "evidence": [ { "id": "0050958", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050958" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of protein localization to chromatin", "id": "GO:1905634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905634", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "regulation of nucleocytoplasmic transport", "id": "GO:0046822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046822", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "positive regulation of RNA polymerase II transcription preinitiation complex assembly", "id": "GO:0045899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045899", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated heterochromatin formation", "id": "GO:0031048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031048", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "RITS complex assembly", "id": "GO:1904802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904802", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "DUBm complex", "id": "GO:0071819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071819", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "SLIK (SAGA-like) complex", "id": "GO:0046695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046695", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "P53165", "url": "https://www.uniprot.org/uniprotkb/P53165" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53165-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Thr183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Thr190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Thr200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Thr202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Thr205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Thr405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Ser479", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "535", "end_pos": "535", "site_lbl": "Thr535", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "614", "end_pos": "614", "site_lbl": "Ser614", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" }, { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "648", "end_pos": "648", "site_lbl": "Ser648", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" } ] } ] }, { "uniprot_canonical_ac": "P53165-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Tyr652", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003034", "url": "https://www.yeastgenome.org/locus/S000003034" } ] } ] } ], "record_id": "P53165-1" }, { "uniprot_canonical_ac": "P53166-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 561, "chemical_mass": 63058.0, "gene_names": "MRH4;MRH4", "protein_name": "ATP-dependent RNA helicase MRH4, mitochondrial", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "pmid": "" }, { "name": "mitochondrial ribosomal large subunit rRNA binding", "id": "GO:1990400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990400", "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "pmid": "" } ], "biological_process": [ { "name": "RNA metabolic process", "id": "GO:0016070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016070", "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "pmid": "" }, { "name": "mitochondrial large ribosomal subunit assembly", "id": "GO:1902775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902775", "evidence": [ { "database": "UniProtKB", "id": "P53166", "url": "https://www.uniprot.org/uniprotkb/P53166" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53166-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53166" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53166-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003032", "url": "https://www.yeastgenome.org/locus/S000003032" }, { "database": "iPTMnet", "id": "P53166", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53166" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53166-1" }, { "uniprot_canonical_ac": "P53169-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53169", "url": "https://www.uniprot.org/uniprotkb/P53169" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 641, "chemical_mass": 73102.0, "gene_names": "YBP2;YBH1;YBP2", "protein_name": "YAP1-binding protein 2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53169", "url": "https://www.uniprot.org/uniprotkb/P53169" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P53169", "url": "https://www.uniprot.org/uniprotkb/P53169" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P53169", "url": "https://www.uniprot.org/uniprotkb/P53169" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P53169", "url": "https://www.uniprot.org/uniprotkb/P53169" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53169-1" }, { "uniprot_canonical_ac": "P53170-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53170", "url": "https://www.uniprot.org/uniprotkb/P53170" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 491, "chemical_mass": 57294.0, "gene_names": "PKP2;PKP2", "protein_name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase 2, mitochondrial", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0090126", "name": "branched-chain keto acid dehydrogenase kinase deficiency", "description": "An amino acid metabolic disorder that is characterized by autism, epilepsy, intellectual disability, and reduced levels of branched-chain amino acids that has_material_basis_in homozygous mutation in the branched chain keto acid dehydrogenase kinase gene (BCKDK) on chromosome 16p11.", "url": "https://disease-ontology.org/term/DOID:0090126", "evidence": [ { "id": "0090126", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090126" } ], "weight": 0.0 }, { "disease_id": "DOID:14228", "name": "oligospermia", "description": "A male fertility issue defined as a low sperm concentration in the ejaculate.", "url": "https://disease-ontology.org/term/DOID:14228", "evidence": [ { "id": "14228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14228" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "pyruvate dehydrogenase (acetyl-transferring) kinase activity", "id": "GO:0004740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004740", "evidence": [ { "database": "UniProtKB", "id": "P53170", "url": "https://www.uniprot.org/uniprotkb/P53170" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P53170", "url": "https://www.uniprot.org/uniprotkb/P53170" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P53170", "url": "https://www.uniprot.org/uniprotkb/P53170" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53170", "url": "https://www.uniprot.org/uniprotkb/P53170" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P53170", "url": "https://www.uniprot.org/uniprotkb/P53170" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of glucose metabolic process", "id": "GO:0010906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010906", "evidence": [ { "database": "UniProtKB", "id": "P53170", "url": "https://www.uniprot.org/uniprotkb/P53170" } ], "pmid": "" }, { "name": "regulation of pyruvate decarboxylation to acetyl-CoA", "id": "GO:0010510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010510", "evidence": [ { "database": "UniProtKB", "id": "P53170", "url": "https://www.uniprot.org/uniprotkb/P53170" } ], "pmid": "" }, { "name": "regulation of mitophagy", "id": "GO:1901524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901524", "evidence": [ { "database": "UniProtKB", "id": "P53170", "url": "https://www.uniprot.org/uniprotkb/P53170" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53170-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Thr327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53170" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53170-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Ser330", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53170" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53170-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Ser334", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53170" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53170-1", "start_pos": "335", "end_pos": "335", "site_lbl": "Tyr335", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53170" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53170-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53170" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53170-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Ser355", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53170" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53170-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003027", "url": "https://www.yeastgenome.org/locus/S000003027" }, { "database": "iPTMnet", "id": "P53170", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53170-1" }, { "uniprot_canonical_ac": "P53173-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 138, "chemical_mass": 15930.0, "gene_names": "ERV14;ERV14", "protein_name": "ER-derived vesicles protein ERV14", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" } ], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" }, { "name": "cargo receptor activity", "id": "GO:0038024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038024", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" } ], "biological_process": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" }, { "name": "regulation of AMPA receptor activity", "id": "GO:2000311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000311", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" }, { "name": "negative regulation of receptor localization to synapse", "id": "GO:1902684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902684", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" }, { "name": "axial cellular bud site selection", "id": "GO:0007120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007120", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" }, { "name": "ascospore formation", "id": "GO:0030437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030437", "evidence": [ { "database": "UniProtKB", "id": "P53173", "url": "https://www.uniprot.org/uniprotkb/P53173" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53173-1" }, { "uniprot_canonical_ac": "P53176-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 234, "chemical_mass": 27241.0, "gene_names": "MST27;DUP2;MST27", "protein_name": "Multicopy suppressor of SEC21 protein 27", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "pmid": "" }, { "name": "COPI-coated vesicle membrane", "id": "GO:0030663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030663", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "pmid": "" }, { "name": "vesicle organization", "id": "GO:0016050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016050", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53176-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003019", "url": "https://www.yeastgenome.org/locus/S000003019" }, { "database": "iPTMnet", "id": "P53176", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53176" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53176-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003019", "url": "https://www.yeastgenome.org/locus/S000003019" }, { "database": "iPTMnet", "id": "P53176", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53176" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53176-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Thr3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53176", "url": "https://www.uniprot.org/uniprotkb/P53176" } ] } ] } ], "record_id": "P53176-1" }, { "uniprot_canonical_ac": "P53178-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53178", "url": "https://www.uniprot.org/uniprotkb/P53178" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 202, "chemical_mass": 22661.0, "gene_names": "ALG13;ALG13", "protein_name": "UDP-N-acetylglucosamine transferase subunit ALG13", "disease": [ { "disease_id": "DOID:0080470", "name": "developmental and epileptic encephalopathy 36", "description": "A developmental and epileptic encephalopathy characterized by X-linked dominant inheritance of infantile onset of seizures, delayed psychomotor development and in some patients dysmorphic features that has_material_basis_in heterozygous mutation in the ALG13 gene on chromosome Xq23.", "url": "https://disease-ontology.org/term/DOID:0080470", "evidence": [ { "id": "0080470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080470" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53178", "url": "https://www.uniprot.org/uniprotkb/P53178" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53178", "url": "https://www.uniprot.org/uniprotkb/P53178" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53178", "url": "https://www.uniprot.org/uniprotkb/P53178" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53178", "url": "https://www.uniprot.org/uniprotkb/P53178" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine transferase complex", "id": "GO:0043541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043541", "evidence": [ { "database": "UniProtKB", "id": "P53178", "url": "https://www.uniprot.org/uniprotkb/P53178" } ], "pmid": "" }, { "name": "cytoplasmic side of Golgi membrane", "id": "GO:0098548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098548", "evidence": [ { "database": "UniProtKB", "id": "P53178", "url": "https://www.uniprot.org/uniprotkb/P53178" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P53178", "url": "https://www.uniprot.org/uniprotkb/P53178" } ], "pmid": "" }, { "name": "N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity", "id": "GO:0004577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004577", "evidence": [ { "database": "UniProtKB", "id": "P53178", "url": "https://www.uniprot.org/uniprotkb/P53178" } ], "pmid": "" } ], "biological_process": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "P53178", "url": "https://www.uniprot.org/uniprotkb/P53178" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53178-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003015", "url": "https://www.yeastgenome.org/locus/S000003015" }, { "database": "iPTMnet", "id": "P53178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53178" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53178-1" }, { "uniprot_canonical_ac": "P53184-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 216, "chemical_mass": 24993.0, "gene_names": "PNC1;PNC1", "protein_name": "Nicotinamidase", "disease": [], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "pmid": "" }, { "name": "rDNA heterochromatin formation", "id": "GO:0000183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000183", "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "pmid": "" }, { "name": "nicotinate nucleotide salvage", "id": "GO:0019358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019358", "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "pmid": "" }, { "name": "negative regulation of DNA amplification", "id": "GO:1904524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904524", "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "pmid": "" }, { "name": "nicotinamidase activity", "id": "GO:0008936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008936", "evidence": [ { "database": "UniProtKB", "id": "P53184", "url": "https://www.uniprot.org/uniprotkb/P53184" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53184-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003005", "url": "https://www.yeastgenome.org/locus/S000003005" }, { "database": "iPTMnet", "id": "P53184", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53184" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53184-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53184", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53184" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003005", "url": "https://www.yeastgenome.org/locus/S000003005" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53184-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003005", "url": "https://www.yeastgenome.org/locus/S000003005" }, { "database": "iPTMnet", "id": "P53184", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53184" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53184-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003005", "url": "https://www.yeastgenome.org/locus/S000003005" }, { "database": "iPTMnet", "id": "P53184", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53184" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53184-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Thr85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003005", "url": "https://www.yeastgenome.org/locus/S000003005" }, { "database": "iPTMnet", "id": "P53184", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53184" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53184-1" }, { "uniprot_canonical_ac": "P53191-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 635, "chemical_mass": 70617.0, "gene_names": "PIB2;PIB2", "protein_name": "Glutamine sensor PIB2", "disease": [], "biological_process": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" } ], "pmid": "" }, { "name": "amino acid sensor activity", "id": "GO:0140785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140785", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" } ], "pmid": "" }, { "name": "L-cysteine binding", "id": "GO:1902485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902485", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53191-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 377, "start_aa": "Ser", "end_pos": 377, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser377", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Ser379", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 379, "start_aa": "Ser", "end_pos": 379, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser379", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Ser381", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 381, "start_aa": "Ser", "end_pos": 381, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser381", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Ser392", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 392, "start_aa": "Ser", "end_pos": 392, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser392", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 393, "start_aa": "Ser", "end_pos": 393, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser393", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Ser395", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 395, "start_aa": "Ser", "end_pos": 395, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser395", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 396, "start_aa": "Ser", "end_pos": 396, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser396", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 399, "start_aa": "Ser", "end_pos": 399, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser399", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Ser402", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 402, "start_aa": "Ser", "end_pos": 402, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser402", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Ser403", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 403, "start_aa": "Ser", "end_pos": 403, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser403", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 407, "start_aa": "Ser", "end_pos": 407, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser407", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 96, "start_aa": "Ser", "end_pos": 96, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser96", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Ser97", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 97, "start_aa": "Ser", "end_pos": 97, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser97", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53191", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53191" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Thr102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Thr10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Ser150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Thr156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Thr160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Ser165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Thr172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Thr209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Thr210", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Thr262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "31622882", "url": "https://glygen.org/publication/PubMed/31622882" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Ser268", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Ser270", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Ser300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Ser310", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Thr346", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Thr401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Ser424", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "432", "end_pos": "432", "site_lbl": "Thr432", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Ser434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "31622882", "url": "https://glygen.org/publication/PubMed/31622882" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Thr52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "579", "end_pos": "579", "site_lbl": "Ser579", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "580", "end_pos": "580", "site_lbl": "Ser580", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "592", "end_pos": "592", "site_lbl": "Thr592", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Thr68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Thr98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002991", "url": "https://www.yeastgenome.org/locus/S000002991" }, { "database": "iPTMnet", "id": "P53191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53191" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Pro337", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "Mildly decreases interaction with and activation of TOR1 in response to glutamine. Sensitive to rapamycin.", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "34535752", "url": "https://glygen.org/publication/PubMed/34535752" } ] }, { "sequence_org": "P", "sequence_mut": "S", "comment": "Decreases interaction with and activation of TOR1.", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "29698392", "url": "https://glygen.org/publication/PubMed/29698392" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Leu340", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Decreases interaction with and activation of TOR1 in response to glutamine. Sensitive to rapamycin.", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "34535752", "url": "https://glygen.org/publication/PubMed/34535752" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Arg341", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Abolishes interaction with and activation of TOR1 in response to glutamine. Sensitive to rapamycin.", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "34535752", "url": "https://glygen.org/publication/PubMed/34535752" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Arg475", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreases localization to the vacuolar membrane and results in rapamycin sensitivity; when associated with S-522.", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "29698392", "url": "https://glygen.org/publication/PubMed/29698392" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Cys522", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Decreases localization to the vacuolar membrane and results in rapamycin sensitivity; when associated with A-475.", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "29698392", "url": "https://glygen.org/publication/PubMed/29698392" } ] } ] }, { "uniprot_canonical_ac": "P53191-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Val626", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Increases activity in presence of glutamine.", "evidence": [ { "database": "UniProtKB", "id": "P53191", "url": "https://www.uniprot.org/uniprotkb/P53191" }, { "database": "PubMed", "id": "34535752", "url": "https://glygen.org/publication/PubMed/34535752" } ] } ] } ], "record_id": "P53191-1" }, { "uniprot_canonical_ac": "P53192-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 235, "chemical_mass": 27092.0, "gene_names": "GET1;GET1;MDM39", "protein_name": "Golgi to ER traffic protein 1", "disease": [], "biological_process": [ { "name": "protein insertion into ER membrane", "id": "GO:0045048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045048", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" }, { "name": "establishment of protein localization to endoplasmic reticulum membrane", "id": "GO:0097051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097051", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" }, { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" }, { "name": "GET complex", "id": "GO:0043529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043529", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" }, { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "P53192", "url": "https://www.uniprot.org/uniprotkb/P53192" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53192-1" }, { "uniprot_canonical_ac": "P53193-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 184, "chemical_mass": 21778.0, "gene_names": "JAC1;JAC1;SEO2", "protein_name": "J-type co-chaperone JAC1, mitochondrial", "disease": [ { "disease_id": "DOID:0061007", "name": "sideroblastic anemia 5", "description": "A sideroblastic anemia that is characterized by abnormal iron accumulation in the mitochondria or erythroid cells that has_material_basis_in compound heterozygous mutation in the HSCB gene on chromosome 22q12.", "url": "https://disease-ontology.org/term/DOID:0061007", "evidence": [ { "id": "0061007", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061007" } ], "weight": 0.0 } ], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" }, { "name": "protein complex oligomerization", "id": "GO:0051259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051259", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" }, { "name": "aerobic respiration", "id": "GO:0009060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009060", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" }, { "name": "[2Fe-2S] cluster assembly", "id": "GO:0044571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044571", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" }, { "name": "[4Fe-4S] cluster assembly", "id": "GO:0044572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044572", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53193-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Lys20", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Decreases JAC1 ATPase activator activity; when associated with A-35; S-38 and L-41. Abolishes JAC1 ATPase activator activity; when associated with A-35; S-38; L-41 and A-48.", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" }, { "database": "PubMed", "id": "26545917", "url": "https://glygen.org/publication/PubMed/26545917" } ] } ] }, { "uniprot_canonical_ac": "P53193-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Asp32", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "", "comment": "In JAC1-1; temperature sensitive; causes growth defect at high temperatures.", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" }, { "database": "PubMed", "id": "9813017", "url": "https://glygen.org/publication/PubMed/9813017" } ] } ] }, { "uniprot_canonical_ac": "P53193-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Arg35", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreases JAC1 ATPase activator activity; when associated with A-20; S-38 and L-41. Abolishes JAC1 ATPase activator activity; when associated with A-20; S-38; L-41 and A-48.", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" }, { "database": "PubMed", "id": "26545917", "url": "https://glygen.org/publication/PubMed/26545917" } ] } ] }, { "uniprot_canonical_ac": "P53193-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Lys38", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "S", "comment": "Decreases JAC1 ATPase activator activity; when associated with A-20; A-35 and L-41. Abolishes JAC1 ATPase activator activity; when associated with A-20; A-35; L-41 and A-48.", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" }, { "database": "PubMed", "id": "26545917", "url": "https://glygen.org/publication/PubMed/26545917" } ] } ] }, { "uniprot_canonical_ac": "P53193-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Arg41", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "L", "comment": "Decreases JAC1 ATPase activator activity; when associated with A-20; A-35 and S-38. Abolishes JAC1 ATPase activator activity; when associated with A-20; A-35; S-38 and A-48.", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" }, { "database": "PubMed", "id": "26545917", "url": "https://glygen.org/publication/PubMed/26545917" } ] } ] }, { "uniprot_canonical_ac": "P53193-1", "start_pos": "48", "end_pos": "48", "site_lbl": "His48", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Decreases JAC1 ATPase activator activity. Decreases vegetative cell population growth. Sensitive to high temperature. Abolishes JAC1 ATPase activator activity; when associated with A-20; A-35; S-38 and L-41.", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" }, { "database": "PubMed", "id": "26545917", "url": "https://glygen.org/publication/PubMed/26545917" } ] } ] }, { "uniprot_canonical_ac": "P53193-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Pro49", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "Decreases JAC1 ATPase activator activity. Decreases vegetative cell population growth. Sensitive to high temperature.", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" }, { "database": "PubMed", "id": "26545917", "url": "https://glygen.org/publication/PubMed/26545917" } ] } ] }, { "uniprot_canonical_ac": "P53193-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Asp50", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Decreases JAC1 ATPase activator activity. Decreases vegetative cell population growth. Sensitive to high temperature.", "evidence": [ { "database": "UniProtKB", "id": "P53193", "url": "https://www.uniprot.org/uniprotkb/P53193" }, { "database": "PubMed", "id": "26545917", "url": "https://glygen.org/publication/PubMed/26545917" } ] } ] } ], "record_id": "P53193-1" }, { "uniprot_canonical_ac": "P53195-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53195", "url": "https://www.uniprot.org/uniprotkb/P53195" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 279, "chemical_mass": 31775.0, "gene_names": "COG7;COD5;COG7", "protein_name": "Conserved oligomeric Golgi complex subunit 7", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P53195", "url": "https://www.uniprot.org/uniprotkb/P53195" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53195", "url": "https://www.uniprot.org/uniprotkb/P53195" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53195", "url": "https://www.uniprot.org/uniprotkb/P53195" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "P53195", "url": "https://www.uniprot.org/uniprotkb/P53195" } ], "pmid": "" } ], "biological_process": [ { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "P53195", "url": "https://www.uniprot.org/uniprotkb/P53195" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P53195", "url": "https://www.uniprot.org/uniprotkb/P53195" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P53195", "url": "https://www.uniprot.org/uniprotkb/P53195" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53195-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53195", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53195" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002973", "url": "https://www.yeastgenome.org/locus/S000002973" } ] } ] } ], "record_id": "P53195-1" }, { "uniprot_canonical_ac": "P53197-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 566, "chemical_mass": 62821.0, "gene_names": "CDH1;CDH1;HCT1", "protein_name": "APC/C activator protein CDH1", "disease": [ { "disease_id": "DOID:0070378", "name": "developmental and epileptic encephalopathy 109", "description": "A developmental and epileptic encephalopathy characterized by onset of various types of seizures in the first months or years of life that has_material_basis_in heterozygous mutation in the FZR1 gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0070378", "evidence": [ { "id": "0070378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070378" } ], "weight": 0.0 }, { "disease_id": "DOID:14566", "name": "disease of cellular proliferation", "description": "A disease that is characterized by abnormally rapid cell division.", "url": "https://disease-ontology.org/term/DOID:14566", "evidence": [ { "id": "14566", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14566" } ], "weight": 0.0 } ], "biological_process": [ { "name": "deactivation of mitotic spindle assembly checkpoint", "id": "GO:1902426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902426", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "positive regulation of mitotic metaphase/anaphase transition", "id": "GO:0045842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045842", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000060", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "positive regulation of anaphase-promoting complex-dependent catabolic process", "id": "GO:1905786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905786", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "negative regulation of mitotic spindle pole body separation", "id": "GO:0010697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010697", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "positive regulation of mitotic actomyosin contractile ring contraction", "id": "GO:1903473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903473", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" } ], "molecular_function": [ { "name": "anaphase-promoting complex binding", "id": "GO:0010997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010997", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" }, { "name": "ubiquitin ligase activator activity", "id": "GO:1990757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990757", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53197-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "19853567", "url": "https://glygen.org/publication/PubMed/19853567" }, { "database": "PubMed", "id": "20089834", "url": "https://glygen.org/publication/PubMed/20089834" }, { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Thr12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-16; A-42; A-157; A-169; A-173; A-176; A-227 and A-239.", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Thr136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "17349956", "url": "https://glygen.org/publication/PubMed/17349956" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" }, { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Thr157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "16688214", "url": "https://glygen.org/publication/PubMed/16688214" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-12; A-16; A-42; A-169; A-173; A-176; A-227 and A-239.", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Ser169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "16688214", "url": "https://glygen.org/publication/PubMed/16688214" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-12; A-16; A-42; A-157; A-173; A-176; A-227 and A-239.", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "16688214", "url": "https://glygen.org/publication/PubMed/16688214" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-12; A-42; A-157; A-169; A-173; A-176; A-227 and A-239.", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Thr173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "16688214", "url": "https://glygen.org/publication/PubMed/16688214" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-12; A-16; A-42; A-157; A-169; A-176; A-227 and A-239.", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Thr176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "16688214", "url": "https://glygen.org/publication/PubMed/16688214" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-12; A-16; A-42; A-157; A-169; A-173; A-227 and A-239.", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Thr189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" }, { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "17349956", "url": "https://glygen.org/publication/PubMed/17349956" }, { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Tyr204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Ser213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" }, { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" }, { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Ser227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-12; A-16; A-42; A-157; A-169; A-173; A-176 and A-239.", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "17349956", "url": "https://glygen.org/publication/PubMed/17349956" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "16688214", "url": "https://glygen.org/publication/PubMed/16688214" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-12; A-16; A-42; A-157; A-169; A-173; A-176 and A-227.", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "19853567", "url": "https://glygen.org/publication/PubMed/19853567" }, { "database": "PubMed", "id": "20089834", "url": "https://glygen.org/publication/PubMed/20089834" }, { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "17349956", "url": "https://glygen.org/publication/PubMed/17349956" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "418", "end_pos": "418", "site_lbl": "Ser418", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Ser42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "16688214", "url": "https://glygen.org/publication/PubMed/16688214" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-12; A-16; A-157; A-169; A-173; A-176; A-227 and A-239.", "evidence": [ { "database": "UniProtKB", "id": "P53197", "url": "https://www.uniprot.org/uniprotkb/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Ser436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "9831566", "url": "https://glygen.org/publication/PubMed/9831566" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "18500339", "url": "https://glygen.org/publication/PubMed/18500339" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" }, { "database": "SGD", "id": "S000002971", "url": "https://www.yeastgenome.org/locus/S000002971" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "17349956", "url": "https://glygen.org/publication/PubMed/17349956" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Thr51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "17349956", "url": "https://glygen.org/publication/PubMed/17349956" } ] } ] }, { "uniprot_canonical_ac": "P53197-1", "start_pos": "556", "end_pos": "556", "site_lbl": "Ser556", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53197" }, { "database": "PubMed", "id": "15467459", "url": "https://glygen.org/publication/PubMed/15467459" } ] } ] } ], "record_id": "P53197-1" }, { "uniprot_canonical_ac": "P53201-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 476, "chemical_mass": 55213.0, "gene_names": "SWC4;EAF2;GOD1;SWC4", "protein_name": "SWR1-complex protein 4", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "P53201", "url": "https://www.uniprot.org/uniprotkb/P53201" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53201-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Thr105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003234", "url": "https://www.yeastgenome.org/locus/S000003234" }, { "database": "iPTMnet", "id": "P53201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53201-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003234", "url": "https://www.yeastgenome.org/locus/S000003234" }, { "database": "iPTMnet", "id": "P53201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53201-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003234", "url": "https://www.yeastgenome.org/locus/S000003234" }, { "database": "iPTMnet", "id": "P53201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53201" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53201-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003234", "url": "https://www.yeastgenome.org/locus/S000003234" }, { "database": "iPTMnet", "id": "P53201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53201-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003234", "url": "https://www.yeastgenome.org/locus/S000003234" }, { "database": "iPTMnet", "id": "P53201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53201-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003234", "url": "https://www.yeastgenome.org/locus/S000003234" }, { "database": "iPTMnet", "id": "P53201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53201" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53201-1", "start_pos": "373", "end_pos": "373", "site_lbl": "Ser373", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003234", "url": "https://www.yeastgenome.org/locus/S000003234" }, { "database": "iPTMnet", "id": "P53201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53201-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Ser403", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003234", "url": "https://www.yeastgenome.org/locus/S000003234" }, { "database": "iPTMnet", "id": "P53201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53201-1" }, { "uniprot_canonical_ac": "P53202-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 744, "chemical_mass": 86115.0, "gene_names": "CUL3;CUL3", "protein_name": "Cullin-3", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060822", "name": "syndromic X-linked intellectual disability Cabezas type", "description": "A syndromic X-linked intellectual disability characterized by intellectual deficit, muscle wasting, short stature, hypogonadism, and abnormal gait, with variable occurrence of prominent lower lip, kyphosis, joint hyperextensibility, tremor, decreased fine motor coordination and impaired speech that has_material_basis_in mutation in the CUL4B gene on chromosome Xq24.", "url": "https://disease-ontology.org/term/DOID:0060822", "evidence": [ { "id": "0060822", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060822" } ], "weight": 0.0 }, { "disease_id": "DOID:0061147", "name": "neurodevelopmental disorder with or without autism or seizures", "description": "An autosomal dominant intellectual developmental disorder characterized by global developmental delay apparent in infancy, impaired intellectual development, and speech delay. Some patients develop seizures, and may show regression after onset of seizures that has_material_basis_in heterozygous mutation in the CUL3 gene on chromosome 2q36.", "url": "https://disease-ontology.org/term/DOID:0061147", "evidence": [ { "id": "0061147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061147" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:4479", "name": "pseudohypoaldosteronism", "description": "", "url": "https://disease-ontology.org/term/DOID:4479", "evidence": [ { "id": "4479", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4479" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" }, { "name": "ubiquitin ligase complex scaffold activity", "id": "GO:0160072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160072", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" }, { "name": "global genome nucleotide-excision repair", "id": "GO:0070911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070911", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "P53202", "url": "https://www.uniprot.org/uniprotkb/P53202" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53202-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Thr713", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003235", "url": "https://www.yeastgenome.org/locus/S000003235" }, { "database": "iPTMnet", "id": "P53202", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53202" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53202-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Ser715", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003235", "url": "https://www.yeastgenome.org/locus/S000003235" }, { "database": "iPTMnet", "id": "P53202", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53202" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53202-1" }, { "uniprot_canonical_ac": "P53204-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53204", "url": "https://www.uniprot.org/uniprotkb/P53204" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 395, "chemical_mass": 44909.0, "gene_names": "NMA2;NMA2", "protein_name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "disease": [ { "disease_id": "DOID:0110005", "name": "Leber congenital amaurosis 9", "description": "A Leber congenital amaurosis that has_material_basis_in mutation in the NMNAT1 gene on chromosome 1p36.", "url": "https://disease-ontology.org/term/DOID:0110005", "evidence": [ { "id": "0110005", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110005" } ], "weight": 0.0 }, { "disease_id": "DOID:0112290", "name": "spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis", "description": "A syndrome characterized by early-onset retinal degeneration, sensorineural hearing loss, short stature, vertebral anomalies, epiphyseal dysplasia, and motor and intellectual delay that has_material_basis_in homozygous or compound heterozygous mutation in NMNAT1 on chromosome 1p36.22.", "url": "https://disease-ontology.org/term/DOID:0112290", "evidence": [ { "id": "0112290", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112290" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P53204", "url": "https://www.uniprot.org/uniprotkb/P53204" } ], "pmid": "" }, { "name": "nicotinate-nucleotide adenylyltransferase activity", "id": "GO:0004515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004515", "evidence": [ { "database": "UniProtKB", "id": "P53204", "url": "https://www.uniprot.org/uniprotkb/P53204" } ], "pmid": "" }, { "name": "nicotinamide-nucleotide adenylyltransferase activity", "id": "GO:0000309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000309", "evidence": [ { "database": "UniProtKB", "id": "P53204", "url": "https://www.uniprot.org/uniprotkb/P53204" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53204", "url": "https://www.uniprot.org/uniprotkb/P53204" } ], "pmid": "" } ], "biological_process": [ { "name": "NAD+ biosynthetic process", "id": "GO:0009435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009435", "evidence": [ { "database": "UniProtKB", "id": "P53204", "url": "https://www.uniprot.org/uniprotkb/P53204" } ], "pmid": "" }, { "name": "NAD+ biosynthetic process via the salvage pathway", "id": "GO:0034355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034355", "evidence": [ { "database": "UniProtKB", "id": "P53204", "url": "https://www.uniprot.org/uniprotkb/P53204" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53204-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003242", "url": "https://www.yeastgenome.org/locus/S000003242" }, { "database": "iPTMnet", "id": "P53204", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53204" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53204-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53204", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53204" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003242", "url": "https://www.yeastgenome.org/locus/S000003242" } ] } ] }, { "uniprot_canonical_ac": "P53204-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53204", "url": "https://www.uniprot.org/uniprotkb/P53204" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P53204", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53204" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003242", "url": "https://www.yeastgenome.org/locus/S000003242" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53204-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Ser89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53204", "url": "https://www.uniprot.org/uniprotkb/P53204" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53204", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53204" }, { "database": "SGD", "id": "S000003242", "url": "https://www.yeastgenome.org/locus/S000003242" } ] } ] }, { "uniprot_canonical_ac": "P53204-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53204", "url": "https://www.uniprot.org/uniprotkb/P53204" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53204", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53204" }, { "database": "SGD", "id": "S000003242", "url": "https://www.yeastgenome.org/locus/S000003242" } ] } ] }, { "uniprot_canonical_ac": "P53204-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003242", "url": "https://www.yeastgenome.org/locus/S000003242" }, { "database": "iPTMnet", "id": "P53204", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53204" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53204-1" }, { "uniprot_canonical_ac": "P53207-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53207", "url": "https://www.uniprot.org/uniprotkb/P53207" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 620, "chemical_mass": 71383.0, "gene_names": "SNU71;SNU71", "protein_name": "U1 small nuclear ribonucleoprotein component SNU71", "disease": [], "cellular_component": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "P53207", "url": "https://www.uniprot.org/uniprotkb/P53207" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53207", "url": "https://www.uniprot.org/uniprotkb/P53207" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53207", "url": "https://www.uniprot.org/uniprotkb/P53207" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "P53207", "url": "https://www.uniprot.org/uniprotkb/P53207" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P53207", "url": "https://www.uniprot.org/uniprotkb/P53207" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P53207", "url": "https://www.uniprot.org/uniprotkb/P53207" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "P53207", "url": "https://www.uniprot.org/uniprotkb/P53207" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53207-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Thr351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Ser410", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Ser430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Ser458", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "512", "end_pos": "512", "site_lbl": "Ser512", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53207", "url": "https://www.uniprot.org/uniprotkb/P53207" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "513", "end_pos": "513", "site_lbl": "Ser513", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "514", "end_pos": "514", "site_lbl": "Ser514", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53207", "url": "https://www.uniprot.org/uniprotkb/P53207" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Ser54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53207-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003245", "url": "https://www.yeastgenome.org/locus/S000003245" }, { "database": "iPTMnet", "id": "P53207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53207" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53207-1" }, { "uniprot_canonical_ac": "P53208-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53208", "url": "https://www.uniprot.org/uniprotkb/P53208" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 328, "chemical_mass": 37937.0, "gene_names": "EAT1;EAT1", "protein_name": "Ethanol acetyltransferase 1", "disease": [], "molecular_function": [ { "name": "acetyl-CoA hydrolase activity", "id": "GO:0003986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003986", "evidence": [ { "database": "UniProtKB", "id": "P53208", "url": "https://www.uniprot.org/uniprotkb/P53208" } ], "pmid": "" }, { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "P53208", "url": "https://www.uniprot.org/uniprotkb/P53208" } ], "pmid": "" }, { "name": "C-acetyltransferase activity", "id": "GO:0016453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016453", "evidence": [ { "database": "UniProtKB", "id": "P53208", "url": "https://www.uniprot.org/uniprotkb/P53208" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53208", "url": "https://www.uniprot.org/uniprotkb/P53208" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "P53208", "url": "https://www.uniprot.org/uniprotkb/P53208" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53208-1" }, { "uniprot_canonical_ac": "P53218-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 158, "chemical_mass": 18210.0, "gene_names": "POP6;POP6", "protein_name": "Ribonucleases P/MRP protein subunit POP6", "disease": [], "cellular_component": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "telomerase holoenzyme complex", "id": "GO:0005697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005697", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, RNase MRP-dependent", "id": "GO:0000294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000294", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "intronic box C/D snoRNA processing", "id": "GO:0034965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034965", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" }, { "name": "rRNA primary transcript binding", "id": "GO:0042134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042134", "evidence": [ { "database": "UniProtKB", "id": "P53218", "url": "https://www.uniprot.org/uniprotkb/P53218" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53218-1" }, { "uniprot_canonical_ac": "P53223-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53223", "url": "https://www.uniprot.org/uniprotkb/P53223" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 239, "chemical_mass": 27649.0, "gene_names": "CAX4;CAX4;CWH8", "protein_name": "Dolichyldiphosphatase", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53223", "url": "https://www.uniprot.org/uniprotkb/P53223" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53223", "url": "https://www.uniprot.org/uniprotkb/P53223" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid biosynthetic process", "id": "GO:0008610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008610", "evidence": [ { "database": "UniProtKB", "id": "P53223", "url": "https://www.uniprot.org/uniprotkb/P53223" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "P53223", "url": "https://www.uniprot.org/uniprotkb/P53223" } ], "pmid": "" } ], "molecular_function": [ { "name": "sphingosine-1-phosphate phosphatase activity", "id": "GO:0042392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042392", "evidence": [ { "database": "UniProtKB", "id": "P53223", "url": "https://www.uniprot.org/uniprotkb/P53223" } ], "pmid": "" }, { "name": "dolichyldiphosphatase activity", "id": "GO:0047874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047874", "evidence": [ { "database": "UniProtKB", "id": "P53223", "url": "https://www.uniprot.org/uniprotkb/P53223" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53223-1" }, { "uniprot_canonical_ac": "P53236-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 928, "chemical_mass": 106669.0, "gene_names": "RSC1;RSC1", "protein_name": "Chromatin structure-remodeling complex subunit RSC1", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:3495", "name": "extrahepatic bile duct adenocarcinoma", "description": "An extrahepatic bile duct carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3495", "evidence": [ { "id": "3495", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3495" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4928", "name": "intrahepatic cholangiocarcinoma", "description": "A cholangiocarcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree.", "url": "https://disease-ontology.org/term/DOID:4928", "evidence": [ { "id": "4928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4928" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "pmid": "" }, { "name": "regulation of sporulation resulting in formation of a cellular spore", "id": "GO:0042173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042173", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "pmid": "" } ], "cellular_component": [ { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "pmid": "" }, { "name": "RSC-type complex", "id": "GO:0016586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016586", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53236-1", "start_pos": "536", "end_pos": "536", "site_lbl": "Thr536", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 536, "start_aa": "Thr", "end_pos": 536, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr536", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Thr148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Thr178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Thr200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "607", "end_pos": "607", "site_lbl": "Ser607", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "609", "end_pos": "609", "site_lbl": "Ser609", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Thr610", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "631", "end_pos": "631", "site_lbl": "Ser631", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "633", "end_pos": "633", "site_lbl": "Thr633", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "655", "end_pos": "655", "site_lbl": "Ser655", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "664", "end_pos": "664", "site_lbl": "Ser664", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "670", "end_pos": "670", "site_lbl": "Ser670", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53236", "url": "https://www.uniprot.org/uniprotkb/P53236" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "703", "end_pos": "703", "site_lbl": "Ser703", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003288", "url": "https://www.yeastgenome.org/locus/S000003288" }, { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53236-1", "start_pos": "753", "end_pos": "753", "site_lbl": "Ser753", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53236", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53236" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P53236-1" }, { "uniprot_canonical_ac": "P53238-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 335, "chemical_mass": 38342.0, "gene_names": "PEF1;PEF1", "protein_name": "Peflin", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" }, { "name": "site of polarized growth", "id": "GO:0030427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030427", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of COPII vesicle coating", "id": "GO:0003400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003400", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" }, { "name": "axial cellular bud site selection", "id": "GO:0007120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007120", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" }, { "name": "bipolar cellular bud site selection", "id": "GO:0007121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007121", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53238-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003290", "url": "https://www.yeastgenome.org/locus/S000003290" }, { "database": "iPTMnet", "id": "P53238", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53238" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53238-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003290", "url": "https://www.yeastgenome.org/locus/S000003290" }, { "database": "iPTMnet", "id": "P53238", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53238" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53238-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003290", "url": "https://www.yeastgenome.org/locus/S000003290" }, { "database": "iPTMnet", "id": "P53238", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53238" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53238-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53238", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53238" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003290", "url": "https://www.yeastgenome.org/locus/S000003290" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53238-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003290", "url": "https://www.yeastgenome.org/locus/S000003290" }, { "database": "iPTMnet", "id": "P53238", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53238" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53238-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Ser83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003290", "url": "https://www.yeastgenome.org/locus/S000003290" }, { "database": "iPTMnet", "id": "P53238", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53238" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53238-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Glu218", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Induces EGTA and SDS sensitivity.", "evidence": [ { "database": "UniProtKB", "id": "P53238", "url": "https://www.uniprot.org/uniprotkb/P53238" }, { "database": "PubMed", "id": "17640275", "url": "https://glygen.org/publication/PubMed/17640275" } ] } ] } ], "record_id": "P53238-1" }, { "uniprot_canonical_ac": "P53244-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53244", "url": "https://www.uniprot.org/uniprotkb/P53244" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 586, "chemical_mass": 65477.0, "gene_names": "ART5;ART5", "protein_name": "Arrestin-related trafficking adapter 5", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53244", "url": "https://www.uniprot.org/uniprotkb/P53244" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53244", "url": "https://www.uniprot.org/uniprotkb/P53244" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53244", "url": "https://www.uniprot.org/uniprotkb/P53244" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P53244", "url": "https://www.uniprot.org/uniprotkb/P53244" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "P53244", "url": "https://www.uniprot.org/uniprotkb/P53244" } ], "pmid": "" } ], "biological_process": [ { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "P53244", "url": "https://www.uniprot.org/uniprotkb/P53244" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53244-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53244" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53244-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53244" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003300", "url": "https://www.yeastgenome.org/locus/S000003300" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53244-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ser159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003300", "url": "https://www.yeastgenome.org/locus/S000003300" }, { "database": "iPTMnet", "id": "P53244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53244-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003300", "url": "https://www.yeastgenome.org/locus/S000003300" }, { "database": "iPTMnet", "id": "P53244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53244-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003300", "url": "https://www.yeastgenome.org/locus/S000003300" }, { "database": "iPTMnet", "id": "P53244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53244" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53244-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Thr206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003300", "url": "https://www.yeastgenome.org/locus/S000003300" }, { "database": "iPTMnet", "id": "P53244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53244-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53244" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P53244-1" }, { "uniprot_canonical_ac": "P53252-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 339, "chemical_mass": 38349.0, "gene_names": "PIL1;PIL1", "protein_name": "Sphingolipid long chain base-responsive protein PIL1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" }, { "name": "eisosome", "id": "GO:0032126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032126", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" }, { "name": "eisosome filament", "id": "GO:0036286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036286", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" }, { "name": "eisosome assembly", "id": "GO:0070941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070941", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" }, { "name": "protein localization to eisosome filament", "id": "GO:0097446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097446", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53252-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Thr233", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 233, "start_aa": "Thr", "end_pos": 233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "PubMed", "id": "19269952", "url": "https://glygen.org/publication/PubMed/19269952" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Ser131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Tyr158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Ser163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Ser180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "PubMed", "id": "19269952", "url": "https://glygen.org/publication/PubMed/19269952" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Thr237", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Thr271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ser273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Ser299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53252-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53252", "url": "https://www.uniprot.org/uniprotkb/P53252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003318", "url": "https://www.yeastgenome.org/locus/S000003318" }, { "database": "iPTMnet", "id": "P53252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53252" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53252-1" }, { "uniprot_canonical_ac": "P53255-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 507, "chemical_mass": 58206.0, "gene_names": "DRN1;DRN1", "protein_name": "CWF19-like protein DRN1", "disease": [ { "disease_id": "DOID:0080064", "name": "autosomal recessive spinocerebellar ataxia 17", "description": "An autosomal recessive cerebellar ataxia that has_material_basis_in homozygous mutation in the CWF19L1 gene on chromosome 10q24.", "url": "https://disease-ontology.org/term/DOID:0080064", "evidence": [ { "id": "0080064", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080064" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" } ], "pmid": "" }, { "name": "post-mRNA release spliceosomal complex", "id": "GO:0071014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071014", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" } ], "pmid": "" }, { "name": "RNA lariat debranching enzyme activator activity", "id": "GO:0061632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061632", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53255-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53255" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003325", "url": "https://www.yeastgenome.org/locus/S000003325" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53255-1", "start_pos": "476", "end_pos": "476", "site_lbl": "Ser476", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003325", "url": "https://www.yeastgenome.org/locus/S000003325" }, { "database": "iPTMnet", "id": "P53255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53255" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53255-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Cys269", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Causes accumulation of pre-mRNA splicing intermediates.", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" }, { "database": "PubMed", "id": "24919400", "url": "https://glygen.org/publication/PubMed/24919400" } ] } ] }, { "uniprot_canonical_ac": "P53255-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Cys272", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Causes accumulation of pre-mRNA splicing intermediates.", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" }, { "database": "PubMed", "id": "24919400", "url": "https://glygen.org/publication/PubMed/24919400" } ] } ] }, { "uniprot_canonical_ac": "P53255-1", "start_pos": "366", "end_pos": "366", "site_lbl": "His366", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Causes accumulation of pre-mRNA splicing intermediates.", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" }, { "database": "PubMed", "id": "24919400", "url": "https://glygen.org/publication/PubMed/24919400" } ] } ] }, { "uniprot_canonical_ac": "P53255-1", "start_pos": "459", "end_pos": "459", "site_lbl": "Arg459", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Causes accumulation of pre-mRNA splicing intermediates.", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" }, { "database": "PubMed", "id": "24919400", "url": "https://glygen.org/publication/PubMed/24919400" } ] } ] }, { "uniprot_canonical_ac": "P53255-1", "start_pos": "474", "end_pos": "474", "site_lbl": "Trp474", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Causes accumulation of pre-mRNA splicing intermediates.", "evidence": [ { "database": "UniProtKB", "id": "P53255", "url": "https://www.uniprot.org/uniprotkb/P53255" }, { "database": "PubMed", "id": "24919400", "url": "https://glygen.org/publication/PubMed/24919400" } ] } ] } ], "record_id": "P53255-1" }, { "uniprot_canonical_ac": "P53256-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 223, "chemical_mass": 24407.0, "gene_names": "RRP46;RRP46", "protein_name": "Exosome complex component RRP46", "disease": [], "biological_process": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent mRNA catabolic process", "id": "GO:0071042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071042", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "poly(A)-dependent snoRNA 3'-end processing", "id": "GO:0071051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071051", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "P53256", "url": "https://www.uniprot.org/uniprotkb/P53256" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53256-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53256" }, { "database": "PubMed", "id": "16829593", "url": "https://glygen.org/publication/PubMed/16829593" }, { "database": "SGD", "id": "S000003327", "url": "https://www.yeastgenome.org/locus/S000003327" }, { "database": "PubMed", "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53256-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003327", "url": "https://www.yeastgenome.org/locus/S000003327" }, { "database": "iPTMnet", "id": "P53256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53256" }, { "database": "PubMed", "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345" } ] } ] } ], "record_id": "P53256-1" }, { "uniprot_canonical_ac": "P53259-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 346, "chemical_mass": 38815.0, "gene_names": "PCP1;MDM37;PCP1;RBD1;UGO2", "protein_name": "Rhomboid protein 1, mitochondrial", "disease": [ { "disease_id": "DOID:11830", "name": "myopia", "description": "A refractive error characterized by the inability to see farther objects clearly.", "url": "https://disease-ontology.org/term/DOID:11830", "evidence": [ { "id": "11830", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11830" } ], "weight": 0.0 }, { "disease_id": "DOID:2018", "name": "hyperinsulinism", "description": "", "url": "https://disease-ontology.org/term/DOID:2018", "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3652", "name": "Leigh disease", "description": "A cytochrome-c oxidase deficiency disease characterized by progressive loss of mental and movement abilities. Symptoms usually begin between ages of three months and two years and include loss of appetite, vomiting, irritability and seizure activity.", "url": "https://disease-ontology.org/term/DOID:3652", "evidence": [ { "id": "3652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3652" } ], "weight": 0.0 }, { "disease_id": "DOID:705", "name": "Leber hereditary optic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:705", "evidence": [ { "id": "705", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:705" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" } ], "pmid": "" }, { "name": "regulation of mitochondrion organization", "id": "GO:0010821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010821", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" } ], "pmid": "" }, { "name": "signal peptide processing", "id": "GO:0006465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006465", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53259-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Asn202", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Abolishes protease activity.", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" }, { "database": "PubMed", "id": "12901865", "url": "https://glygen.org/publication/PubMed/12901865" } ] } ] }, { "uniprot_canonical_ac": "P53259-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Ser252", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Does not abolish protease activity.", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" }, { "database": "PubMed", "id": "12417197", "url": "https://glygen.org/publication/PubMed/12417197" }, { "database": "PubMed", "id": "12901865", "url": "https://glygen.org/publication/PubMed/12901865" } ] }, { "sequence_org": "S", "sequence_mut": "I", "comment": "Does not abolish protease activity.", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" }, { "database": "PubMed", "id": "12417197", "url": "https://glygen.org/publication/PubMed/12417197" }, { "database": "PubMed", "id": "12901865", "url": "https://glygen.org/publication/PubMed/12901865" } ] } ] }, { "uniprot_canonical_ac": "P53259-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes protease activity.", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" }, { "database": "PubMed", "id": "12417197", "url": "https://glygen.org/publication/PubMed/12417197" }, { "database": "PubMed", "id": "12901865", "url": "https://glygen.org/publication/PubMed/12901865" }, { "database": "PubMed", "id": "12774122", "url": "https://glygen.org/publication/PubMed/12774122" } ] }, { "sequence_org": "S", "sequence_mut": "G", "comment": "Abolishes protease activity.", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" }, { "database": "PubMed", "id": "12417197", "url": "https://glygen.org/publication/PubMed/12417197" }, { "database": "PubMed", "id": "12901865", "url": "https://glygen.org/publication/PubMed/12901865" }, { "database": "PubMed", "id": "12774122", "url": "https://glygen.org/publication/PubMed/12774122" } ] }, { "sequence_org": "S", "sequence_mut": "I", "comment": "Abolishes protease activity.", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" }, { "database": "PubMed", "id": "12417197", "url": "https://glygen.org/publication/PubMed/12417197" }, { "database": "PubMed", "id": "12901865", "url": "https://glygen.org/publication/PubMed/12901865" }, { "database": "PubMed", "id": "12774122", "url": "https://glygen.org/publication/PubMed/12774122" } ] } ] }, { "uniprot_canonical_ac": "P53259-1", "start_pos": "313", "end_pos": "313", "site_lbl": "His313", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes protease activity.", "evidence": [ { "database": "UniProtKB", "id": "P53259", "url": "https://www.uniprot.org/uniprotkb/P53259" }, { "database": "PubMed", "id": "12901865", "url": "https://glygen.org/publication/PubMed/12901865" } ] } ] } ], "record_id": "P53259-1" }, { "uniprot_canonical_ac": "P53261-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 605, "chemical_mass": 69877.0, "gene_names": "NOP7;NOP7;RRP13;YPH1", "protein_name": "Pescadillo homolog", "disease": [ { "disease_id": "DOID:0060479", "name": "Shwachman-Diamond syndrome", "description": "A syndrome characterized by exocrine pancreatic insufficiency, bone marrow failure and skeletal abnormalities.", "url": "https://disease-ontology.org/term/DOID:0060479", "evidence": [ { "id": "0060479", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060479" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "large ribosomal subunit rRNA binding", "id": "GO:0070180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070180", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "PeBoW complex", "id": "GO:0070545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070545", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000466", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53261-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Ser261", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Ser271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Ser288", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Thr293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Ser296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Thr305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Thr308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Thr330", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Thr334", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Ser526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Ser529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53261", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53261" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003335", "url": "https://www.yeastgenome.org/locus/S000003335" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "380", "end_pos": "380", "site_lbl": "Ile380", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "R", "comment": "Temperature sensitive mutant.", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" }, { "database": "PubMed", "id": "12110181", "url": "https://glygen.org/publication/PubMed/12110181" } ] } ] }, { "uniprot_canonical_ac": "P53261-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Trp431", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "R", "comment": "Temperature sensitive mutant.", "evidence": [ { "database": "UniProtKB", "id": "P53261", "url": "https://www.uniprot.org/uniprotkb/P53261" }, { "database": "PubMed", "id": "12110181", "url": "https://glygen.org/publication/PubMed/12110181" } ] } ] } ], "record_id": "P53261-1" }, { "uniprot_canonical_ac": "P53262-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 265, "chemical_mass": 29678.0, "gene_names": "VOA1;VOA1", "protein_name": "V0 assembly protein 1", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V0 domain", "id": "GO:0000220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000220", "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "pmid": "" } ], "biological_process": [ { "name": "endosomal lumen acidification", "id": "GO:0048388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048388", "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "pmid": "" }, { "name": "Golgi lumen acidification", "id": "GO:0061795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061795", "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "pmid": "" } ], "molecular_function": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "P53262", "url": "https://www.uniprot.org/uniprotkb/P53262" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53262-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Asn104", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 104, "start_aa": "Asn", "end_pos": 104, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn104", "evidence": [ { "id": "P53262", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53262#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53262-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Asn172", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 172, "start_aa": "Asn", "end_pos": 172, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn172", "evidence": [ { "id": "P53262", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53262#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53262-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Asn69", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 69, "start_aa": "Asn", "end_pos": 69, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn69", "evidence": [ { "id": "P53262", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53262#ptm_processing" } ] } ] } ], "record_id": "P53262-1" }, { "uniprot_canonical_ac": "P53264-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 445, "chemical_mass": 52045.0, "gene_names": "CLD1;CLD1;G6140", "protein_name": "Cardiolipin-specific deacylase 1, mitochondrial", "disease": [ { "disease_id": "DOID:0050729", "name": "Chanarin-Dorfman syndrome", "description": "A lipid storage disease that is characterized by accumulation of triglycerides in the cytoplasm of leukocytes, muscle, liver, fibroblasts, and other tissues.", "url": "https://disease-ontology.org/term/DOID:0050729", "evidence": [ { "id": "0050729", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050729" } ], "weight": 0.0 }, { "disease_id": "DOID:0060656", "name": "autosomal recessive congenital ichthyosis 1", "description": "An autosomal recessive congenital ichthyosis that is characterized by lamellar ichthyosis, ectropion, eclabium and hyperkeratosis that has_material_basis_in homozygous or compound heterozygous mutation in the TGM1 gene on chromosome 14q11.2.", "url": "https://disease-ontology.org/term/DOID:0060656", "evidence": [ { "id": "0060656", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060656" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidic acid biosynthetic process", "id": "GO:0006654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006654", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" } ], "pmid": "" }, { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" } ], "pmid": "" }, { "name": "cardiolipin acyl-chain remodeling", "id": "GO:0035965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035965", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" } ], "pmid": "" }, { "name": "cardiolipin metabolic process", "id": "GO:0032048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032048", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" } ], "pmid": "" } ], "molecular_function": [ { "name": "lysophosphatidic acid acyltransferase activity", "id": "GO:0042171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042171", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53264-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Thr102", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 102, "start_aa": "Thr", "end_pos": 102, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr102", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P53264-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Thr91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003342", "url": "https://www.yeastgenome.org/locus/S000003342" }, { "database": "iPTMnet", "id": "P53264", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53264" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53264-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Trp170", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "R", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" }, { "database": "PubMed", "id": "24318983", "url": "https://glygen.org/publication/PubMed/24318983" } ] } ] }, { "uniprot_canonical_ac": "P53264-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" }, { "database": "PubMed", "id": "23637464", "url": "https://glygen.org/publication/PubMed/23637464" } ] } ] }, { "uniprot_canonical_ac": "P53264-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Asp392", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" }, { "database": "PubMed", "id": "23637464", "url": "https://glygen.org/publication/PubMed/23637464" } ] } ] }, { "uniprot_canonical_ac": "P53264-1", "start_pos": "424", "end_pos": "424", "site_lbl": "His424", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" }, { "database": "PubMed", "id": "23637464", "url": "https://glygen.org/publication/PubMed/23637464" } ] } ] }, { "uniprot_canonical_ac": "P53264-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Asp429", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P53264", "url": "https://www.uniprot.org/uniprotkb/P53264" }, { "database": "PubMed", "id": "23637464", "url": "https://glygen.org/publication/PubMed/23637464" } ] } ] } ], "record_id": "P53264-1" }, { "uniprot_canonical_ac": "P53271-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53271", "url": "https://www.uniprot.org/uniprotkb/P53271" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 262, "chemical_mass": 30325.0, "gene_names": "COG2;COG2;G6324;SEC35", "protein_name": "Conserved oligomeric Golgi complex subunit 2", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P53271", "url": "https://www.uniprot.org/uniprotkb/P53271" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53271", "url": "https://www.uniprot.org/uniprotkb/P53271" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "P53271", "url": "https://www.uniprot.org/uniprotkb/P53271" } ], "pmid": "" } ], "biological_process": [ { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P53271", "url": "https://www.uniprot.org/uniprotkb/P53271" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P53271", "url": "https://www.uniprot.org/uniprotkb/P53271" } ], "pmid": "" }, { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "P53271", "url": "https://www.uniprot.org/uniprotkb/P53271" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P53271", "url": "https://www.uniprot.org/uniprotkb/P53271" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P53271", "url": "https://www.uniprot.org/uniprotkb/P53271" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "P53271", "url": "https://www.uniprot.org/uniprotkb/P53271" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53271-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003352", "url": "https://www.yeastgenome.org/locus/S000003352" }, { "database": "iPTMnet", "id": "P53271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53271-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003352", "url": "https://www.yeastgenome.org/locus/S000003352" }, { "database": "iPTMnet", "id": "P53271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53271-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Thr160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003352", "url": "https://www.yeastgenome.org/locus/S000003352" }, { "database": "iPTMnet", "id": "P53271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53271-1" }, { "uniprot_canonical_ac": "P53276-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 713, "chemical_mass": 80191.0, "gene_names": "UTP8;UTP8", "protein_name": "U3 small nucleolar RNA-associated protein 8", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" }, { "name": "rDNA heterochromatin", "id": "GO:0033553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033553", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" }, { "name": "t-UTP complex", "id": "GO:0034455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034455", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" }, { "name": "tRNA export from nucleus", "id": "GO:0006409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006409", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" }, { "name": "U3 snoRNA binding", "id": "GO:0034511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034511", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53276-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Thr139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53276", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53276" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53276-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Thr140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003360", "url": "https://www.yeastgenome.org/locus/S000003360" }, { "database": "iPTMnet", "id": "P53276", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53276" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53276-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003360", "url": "https://www.yeastgenome.org/locus/S000003360" }, { "database": "iPTMnet", "id": "P53276", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53276" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53276-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Ser143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003360", "url": "https://www.yeastgenome.org/locus/S000003360" }, { "database": "iPTMnet", "id": "P53276", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53276" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53276-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53276", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53276" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003360", "url": "https://www.yeastgenome.org/locus/S000003360" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53276-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Ser150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53276", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53276" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003360", "url": "https://www.yeastgenome.org/locus/S000003360" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53276-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Ser498", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003360", "url": "https://www.yeastgenome.org/locus/S000003360" }, { "database": "iPTMnet", "id": "P53276", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53276" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53276-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53276", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53276" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003360", "url": "https://www.yeastgenome.org/locus/S000003360" } ] } ] }, { "uniprot_canonical_ac": "P53276-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Thr95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53276", "url": "https://www.uniprot.org/uniprotkb/P53276" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53276", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53276" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003360", "url": "https://www.yeastgenome.org/locus/S000003360" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53276-1" }, { "uniprot_canonical_ac": "P53281-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53281", "url": "https://www.uniprot.org/uniprotkb/P53281" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 241, "chemical_mass": 26139.0, "gene_names": "LSB1;LSB1", "protein_name": "LAS seventeen-binding protein 1", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2526", "name": "prostate adenocarcinoma", "description": "A prostate carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2526", "evidence": [ { "id": "2526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2526" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53281", "url": "https://www.uniprot.org/uniprotkb/P53281" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53281", "url": "https://www.uniprot.org/uniprotkb/P53281" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P53281", "url": "https://www.uniprot.org/uniprotkb/P53281" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034316", "evidence": [ { "database": "UniProtKB", "id": "P53281", "url": "https://www.uniprot.org/uniprotkb/P53281" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53281-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53281" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003368", "url": "https://www.yeastgenome.org/locus/S000003368" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53281-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53281", "url": "https://www.uniprot.org/uniprotkb/P53281" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P53281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53281" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53281-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53281", "url": "https://www.uniprot.org/uniprotkb/P53281" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P53281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53281" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003368", "url": "https://www.yeastgenome.org/locus/S000003368" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53281-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003368", "url": "https://www.yeastgenome.org/locus/S000003368" }, { "database": "iPTMnet", "id": "P53281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53281" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53281-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003368", "url": "https://www.yeastgenome.org/locus/S000003368" }, { "database": "iPTMnet", "id": "P53281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53281" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53281-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003368", "url": "https://www.yeastgenome.org/locus/S000003368" }, { "database": "iPTMnet", "id": "P53281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53281" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53281-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53281", "url": "https://www.uniprot.org/uniprotkb/P53281" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53281" }, { "database": "SGD", "id": "S000003368", "url": "https://www.yeastgenome.org/locus/S000003368" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53281-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003368", "url": "https://www.yeastgenome.org/locus/S000003368" }, { "database": "iPTMnet", "id": "P53281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53281" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53281-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Trp90", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "S", "comment": "Abolishes interaction with LAS17, but not with SUP35. Blocks colocalization with actin.", "evidence": [ { "database": "UniProtKB", "id": "P53281", "url": "https://www.uniprot.org/uniprotkb/P53281" }, { "database": "PubMed", "id": "21777813", "url": "https://glygen.org/publication/PubMed/21777813" } ] } ] } ], "record_id": "P53281-1" }, { "uniprot_canonical_ac": "P53294-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53294", "url": "https://www.uniprot.org/uniprotkb/P53294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 404, "chemical_mass": 46816.0, "gene_names": "PUS6;PUS6", "protein_name": "tRNA pseudouridine(31) synthase", "disease": [], "biological_process": [ { "name": "tRNA pseudouridine synthesis", "id": "GO:0031119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031119", "evidence": [ { "database": "UniProtKB", "id": "P53294", "url": "https://www.uniprot.org/uniprotkb/P53294" } ], "pmid": "" }, { "name": "enzyme-directed rRNA pseudouridine synthesis", "id": "GO:0000455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000455", "evidence": [ { "database": "UniProtKB", "id": "P53294", "url": "https://www.uniprot.org/uniprotkb/P53294" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P53294", "url": "https://www.uniprot.org/uniprotkb/P53294" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "P53294", "url": "https://www.uniprot.org/uniprotkb/P53294" } ], "pmid": "" }, { "name": "tRNA pseudouridine(31) synthase activity", "id": "GO:0160152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160152", "evidence": [ { "database": "UniProtKB", "id": "P53294", "url": "https://www.uniprot.org/uniprotkb/P53294" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53294", "url": "https://www.uniprot.org/uniprotkb/P53294" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53294", "url": "https://www.uniprot.org/uniprotkb/P53294" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53294-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Thr273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53294" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003401", "url": "https://www.yeastgenome.org/locus/S000003401" } ] } ] }, { "uniprot_canonical_ac": "P53294-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Asp168", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P53294", "url": "https://www.uniprot.org/uniprotkb/P53294" }, { "database": "PubMed", "id": "11406626", "url": "https://glygen.org/publication/PubMed/11406626" } ] } ] } ], "record_id": "P53294-1" }, { "uniprot_canonical_ac": "P53296-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53296", "url": "https://www.uniprot.org/uniprotkb/P53296" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 535, "chemical_mass": 61898.0, "gene_names": "ATF2;ATF2;G7135", "protein_name": "Alcohol O-acetyltransferase 2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53296", "url": "https://www.uniprot.org/uniprotkb/P53296" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53296", "url": "https://www.uniprot.org/uniprotkb/P53296" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P53296", "url": "https://www.uniprot.org/uniprotkb/P53296" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53296", "url": "https://www.uniprot.org/uniprotkb/P53296" } ], "pmid": "" } ], "biological_process": [ { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "P53296", "url": "https://www.uniprot.org/uniprotkb/P53296" } ], "pmid": "" }, { "name": "steroid metabolic process", "id": "GO:0008202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008202", "evidence": [ { "database": "UniProtKB", "id": "P53296", "url": "https://www.uniprot.org/uniprotkb/P53296" } ], "pmid": "" }, { "name": "acetate ester metabolic process involved in fermentation", "id": "GO:1901089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901089", "evidence": [ { "database": "UniProtKB", "id": "P53296", "url": "https://www.uniprot.org/uniprotkb/P53296" } ], "pmid": "" } ], "molecular_function": [ { "name": "N-acetyltransferase activity", "id": "GO:0008080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008080", "evidence": [ { "database": "UniProtKB", "id": "P53296", "url": "https://www.uniprot.org/uniprotkb/P53296" } ], "pmid": "" }, { "name": "alcohol O-acetyltransferase activity", "id": "GO:0004026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004026", "evidence": [ { "database": "UniProtKB", "id": "P53296", "url": "https://www.uniprot.org/uniprotkb/P53296" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53296-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003409", "url": "https://www.yeastgenome.org/locus/S000003409" }, { "database": "iPTMnet", "id": "P53296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53296" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53296-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Ser441", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003409", "url": "https://www.yeastgenome.org/locus/S000003409" }, { "database": "iPTMnet", "id": "P53296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53296" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] } ], "record_id": "P53296-1" }, { "uniprot_canonical_ac": "P53297-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 722, "chemical_mass": 78781.0, "gene_names": "PBP1;MRS16;PBP1", "protein_name": "PAB1-binding protein 1", "disease": [ { "disease_id": "DOID:0050955", "name": "spinocerebellar ataxia 2", "description": "An autosomal dominant cerebellar ataxia that is characterized by ataxia, bulbar palsy, peripheral neuropathy chorea and muscle atrophy, has_material_basis_in mutation in the ATXN2 gene.", "url": "https://disease-ontology.org/term/DOID:0050955", "evidence": [ { "id": "0050955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050955" } ], "weight": 0.0 }, { "disease_id": "DOID:0060204", "name": "amyotrophic lateral sclerosis type 13", "description": "An amyotrophic lateral sclerosis where a mutation that has_material_basis_in the ATXN2 gene on chromosome 12 contributes to suscepitbility.", "url": "https://disease-ontology.org/term/DOID:0060204", "evidence": [ { "id": "0060204", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060204" } ], "weight": 0.0 }, { "disease_id": "DOID:0060892", "name": "late onset Parkinson's disease", "description": "A Parkinson's disease characterized by onset of motor symptoms typically after 60 years of age.", "url": "https://disease-ontology.org/term/DOID:0060892", "evidence": [ { "id": "0060892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060892" } ], "weight": 0.0 }, { "disease_id": "DOID:0070515", "name": "chromosome 16p11.2 deletion syndrome, 593-kb", "description": "A chromosomal deletion syndrome characterized by language delay and mild intellectual disability that has_material_basis_in partial deletion of a contiguous 593-kb region of chromosome 16p11.2 (chr16:29.5-30.1 Mb).", "url": "https://disease-ontology.org/term/DOID:0070515", "evidence": [ { "id": "0070515", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070515" } ], "weight": 0.0 }, { "disease_id": "DOID:1441", "name": "autosomal dominant cerebellar ataxia", "description": "A cerebellar ataxia that has_material_basis_in autosomal dominant inheritance.", "url": "https://disease-ontology.org/term/DOID:1441", "evidence": [ { "id": "1441", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1441" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "maintenance of rDNA", "id": "GO:0043007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043007", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "regulation of mitophagy", "id": "GO:1901524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901524", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" }, { "name": "regulation of mating type switching", "id": "GO:0031494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031494", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53297-1", "start_pos": "451", "end_pos": "451", "site_lbl": "Ser451", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 451, "start_aa": "Ser", "end_pos": 451, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser451", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53297", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53297" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "453", "end_pos": "453", "site_lbl": "Ser453", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 453, "start_aa": "Ser", "end_pos": 453, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser453", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53297", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53297" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "456", "end_pos": "456", "site_lbl": "Ser456", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 456, "start_aa": "Ser", "end_pos": 456, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser456", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53297", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53297" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Ser460", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 460, "start_aa": "Ser", "end_pos": 460, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser460", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53297", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53297" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Ser461", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 461, "start_aa": "Ser", "end_pos": 461, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser461", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53297", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53297" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Ser101", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Thr150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Ser178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Ser180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Thr193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Ser213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Ser215", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Thr231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Thr353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Thr355", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Thr434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Ser436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53297", "url": "https://www.uniprot.org/uniprotkb/P53297" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "31455721", "url": "https://glygen.org/publication/PubMed/31455721" }, { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Thr438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "442", "end_pos": "442", "site_lbl": "Ser442", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Thr466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Ser471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Ser479", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53297-1", "start_pos": "499", "end_pos": "499", "site_lbl": "Ser499", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003410", "url": "https://www.yeastgenome.org/locus/S000003410" }, { "database": "iPTMnet", "id": "P53297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53297-1" }, { "uniprot_canonical_ac": "P53298-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53298", "url": "https://www.uniprot.org/uniprotkb/P53298" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 406, "chemical_mass": 47349.0, "gene_names": "OKP1;OKP1", "protein_name": "Inner kinetochore subunit OKP1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53298", "url": "https://www.uniprot.org/uniprotkb/P53298" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P53298", "url": "https://www.uniprot.org/uniprotkb/P53298" } ], "pmid": "" }, { "name": "COMA complex", "id": "GO:0000817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000817", "evidence": [ { "database": "UniProtKB", "id": "P53298", "url": "https://www.uniprot.org/uniprotkb/P53298" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "P53298", "url": "https://www.uniprot.org/uniprotkb/P53298" } ], "pmid": "" }, { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "P53298", "url": "https://www.uniprot.org/uniprotkb/P53298" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P53298", "url": "https://www.uniprot.org/uniprotkb/P53298" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P53298", "url": "https://www.uniprot.org/uniprotkb/P53298" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53298-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003411", "url": "https://www.yeastgenome.org/locus/S000003411" }, { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53298-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Ser111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003411", "url": "https://www.yeastgenome.org/locus/S000003411" }, { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53298-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003411", "url": "https://www.yeastgenome.org/locus/S000003411" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53298-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003411", "url": "https://www.yeastgenome.org/locus/S000003411" }, { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53298-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Thr119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003411", "url": "https://www.yeastgenome.org/locus/S000003411" } ] } ] }, { "uniprot_canonical_ac": "P53298-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003411", "url": "https://www.yeastgenome.org/locus/S000003411" }, { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53298-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Ser329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003411", "url": "https://www.yeastgenome.org/locus/S000003411" }, { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53298-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Thr401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003411", "url": "https://www.yeastgenome.org/locus/S000003411" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53298-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53298-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Tyr67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003411", "url": "https://www.yeastgenome.org/locus/S000003411" }, { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53298-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53298", "url": "https://www.uniprot.org/uniprotkb/P53298" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53298" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003411", "url": "https://www.yeastgenome.org/locus/S000003411" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53298-1" }, { "uniprot_canonical_ac": "P53299-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 105, "chemical_mass": 11286.0, "gene_names": "TIM13;G7157;TIM13", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM13", "disease": [ { "disease_id": "DOID:0050757", "name": "deafness-dystonia-optic neuronopathy syndrome", "description": "A mitochondrial metabolism disease that is characterized by hearing loss that begins early in life, problems with movement, impaired vision, and behavior problems, and has_material_basis_in mutations in the TIMM8A gene resulting in abnormal protein transport within the mitochondria.", "url": "https://disease-ontology.org/term/DOID:0050757", "evidence": [ { "id": "0050757", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050757" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial intermembrane space chaperone complex", "id": "GO:0042719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042719", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" } ], "pmid": "" }, { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" } ], "pmid": "" }, { "name": "protein transporter activity", "id": "GO:0140318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140318", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53299-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Ser100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53299", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53299" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003413", "url": "https://www.yeastgenome.org/locus/S000003413" } ] } ] }, { "uniprot_canonical_ac": "P53299-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53299", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53299" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003413", "url": "https://www.yeastgenome.org/locus/S000003413" } ] } ] }, { "uniprot_canonical_ac": "P53299-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003413", "url": "https://www.yeastgenome.org/locus/S000003413" }, { "database": "iPTMnet", "id": "P53299", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53299" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53299-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003413", "url": "https://www.yeastgenome.org/locus/S000003413" }, { "database": "iPTMnet", "id": "P53299", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53299" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53299-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003413", "url": "https://www.yeastgenome.org/locus/S000003413" }, { "database": "iPTMnet", "id": "P53299", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53299" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53299-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Cys57", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes import into mitochondrion; when associated with S-61.", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" }, { "database": "PubMed", "id": "12941692", "url": "https://glygen.org/publication/PubMed/12941692" } ] } ] }, { "uniprot_canonical_ac": "P53299-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Cys61", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes import into mitochondrion; when associated with S-57.", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" }, { "database": "PubMed", "id": "12941692", "url": "https://glygen.org/publication/PubMed/12941692" } ] } ] }, { "uniprot_canonical_ac": "P53299-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Cys73", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes import into mitochondrion; when associated with S-77.", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" }, { "database": "PubMed", "id": "12941692", "url": "https://glygen.org/publication/PubMed/12941692" } ] } ] }, { "uniprot_canonical_ac": "P53299-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Cys77", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes import into mitochondrion; when associated with S-73.", "evidence": [ { "database": "UniProtKB", "id": "P53299", "url": "https://www.uniprot.org/uniprotkb/P53299" }, { "database": "PubMed", "id": "12941692", "url": "https://glygen.org/publication/PubMed/12941692" } ] } ] } ], "record_id": "P53299-1" }, { "uniprot_canonical_ac": "P53301-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 507, "chemical_mass": 52758.0, "gene_names": "CRH1;CRH1;G7553", "protein_name": "Congo red hypersensitive protein 1", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "pmid": "" }, { "name": "chitin metabolic process", "id": "GO:0006030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006030", "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "pmid": "" } ], "molecular_function": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "pmid": "" }, { "name": "endochitinase activity", "id": "GO:0008843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008843", "evidence": [ { "database": "UniProtKB", "id": "P53301", "url": "https://www.uniprot.org/uniprotkb/P53301" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53301-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Asn117", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 117, "start_aa": "Asn", "end_pos": 117, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn117", "evidence": [ { "id": "P53301", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53301#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53301-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Asn177", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 177, "start_aa": "Asn", "end_pos": 177, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn177", "evidence": [ { "id": "P53301", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53301#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53301-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Asn201", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 201, "start_aa": "Asn", "end_pos": 201, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn201", "evidence": [ { "id": "P53301", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53301#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53301-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Thr170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003421", "url": "https://www.yeastgenome.org/locus/S000003421" }, { "database": "iPTMnet", "id": "P53301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53301-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Ser435", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003421", "url": "https://www.yeastgenome.org/locus/S000003421" }, { "database": "iPTMnet", "id": "P53301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53301-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Thr49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003421", "url": "https://www.yeastgenome.org/locus/S000003421" }, { "database": "iPTMnet", "id": "P53301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53301" }, { "database": "PubMed", "id": "31870255", "url": "https://glygen.org/publication/PubMed/31870255" } ] } ] }, { "uniprot_canonical_ac": "P53301-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003421", "url": "https://www.yeastgenome.org/locus/S000003421" }, { "database": "iPTMnet", "id": "P53301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53301" }, { "database": "PubMed", "id": "31870255", "url": "https://glygen.org/publication/PubMed/31870255" } ] } ] } ], "record_id": "P53301-1" }, { "uniprot_canonical_ac": "P53303-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 486, "chemical_mass": 55072.0, "gene_names": "ZPR1;ZPR1", "protein_name": "Zinc finger chaperone ZPR1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" } ], "pmid": "" }, { "name": "translation elongation factor binding", "id": "GO:0061770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061770", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" } ], "pmid": "" } ], "biological_process": [ { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" } ], "pmid": "" }, { "name": "response to glucose", "id": "GO:0009749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009749", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" } ], "pmid": "" }, { "name": "'de novo' protein folding", "id": "GO:0006458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006458", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53303-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53303-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53303-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Ser262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53303-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53303-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Ser276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53303-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53303-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Thr407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53303", "url": "https://www.uniprot.org/uniprotkb/P53303" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53303-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Ser410", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53303-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Ser412", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53303-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Ser481", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53303-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Ser97", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003443", "url": "https://www.yeastgenome.org/locus/S000003443" }, { "database": "iPTMnet", "id": "P53303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53303" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53303-1" }, { "uniprot_canonical_ac": "P53309-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 568, "chemical_mass": 64328.0, "gene_names": "YAP1802;G8610;YAP1802", "protein_name": "Clathrin coat assembly protein AP180B", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "1-phosphatidylinositol binding", "id": "GO:0005545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005545", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "clathrin heavy chain binding", "id": "GO:0032050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032050", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "vesicle budding from membrane", "id": "GO:0006900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006900", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "clathrin coat assembly", "id": "GO:0048268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048268", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53309-1", "start_pos": "333", "end_pos": "333", "site_lbl": "Thr333", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 333, "start_aa": "Thr", "end_pos": 333, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr333", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P53309-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003473", "url": "https://www.yeastgenome.org/locus/S000003473" }, { "database": "iPTMnet", "id": "P53309", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53309" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53309-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Ser275", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003473", "url": "https://www.yeastgenome.org/locus/S000003473" }, { "database": "iPTMnet", "id": "P53309", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53309" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53309-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003473", "url": "https://www.yeastgenome.org/locus/S000003473" }, { "database": "iPTMnet", "id": "P53309", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53309" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53309-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Ser288", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003473", "url": "https://www.yeastgenome.org/locus/S000003473" }, { "database": "iPTMnet", "id": "P53309", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53309" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53309-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Ser289", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003473", "url": "https://www.yeastgenome.org/locus/S000003473" }, { "database": "iPTMnet", "id": "P53309", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53309" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53309-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Thr290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003473", "url": "https://www.yeastgenome.org/locus/S000003473" }, { "database": "iPTMnet", "id": "P53309", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53309" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53309-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Ser291", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003473", "url": "https://www.yeastgenome.org/locus/S000003473" }, { "database": "iPTMnet", "id": "P53309", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53309" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53309-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003473", "url": "https://www.yeastgenome.org/locus/S000003473" }, { "database": "iPTMnet", "id": "P53309", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53309" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53309-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Ser297", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003473", "url": "https://www.yeastgenome.org/locus/S000003473" }, { "database": "iPTMnet", "id": "P53309", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53309" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53309-1", "start_pos": "449", "end_pos": "449", "site_lbl": "Thr449", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53309", "url": "https://www.uniprot.org/uniprotkb/P53309" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53309", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53309" }, { "database": "SGD", "id": "S000003473", "url": "https://www.yeastgenome.org/locus/S000003473" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P53309-1" }, { "uniprot_canonical_ac": "P53311-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53311", "url": "https://www.uniprot.org/uniprotkb/P53311" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 146, "chemical_mass": 16230.0, "gene_names": "MPC3;FMP43;G8620;MPC3", "protein_name": "Mitochondrial pyruvate carrier 3", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53311", "url": "https://www.uniprot.org/uniprotkb/P53311" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P53311", "url": "https://www.uniprot.org/uniprotkb/P53311" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P53311", "url": "https://www.uniprot.org/uniprotkb/P53311" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "P53311", "url": "https://www.uniprot.org/uniprotkb/P53311" } ], "pmid": "" }, { "name": "mitochondrial pyruvate carrier complex", "id": "GO:7770001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:7770001", "evidence": [ { "database": "UniProtKB", "id": "P53311", "url": "https://www.uniprot.org/uniprotkb/P53311" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyruvate transmembrane transporter activity", "id": "GO:0050833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050833", "evidence": [ { "database": "UniProtKB", "id": "P53311", "url": "https://www.uniprot.org/uniprotkb/P53311" } ], "pmid": "" } ], "biological_process": [ { "name": "pyruvate import into mitochondria", "id": "GO:0006850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006850", "evidence": [ { "database": "UniProtKB", "id": "P53311", "url": "https://www.uniprot.org/uniprotkb/P53311" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53311-1" }, { "uniprot_canonical_ac": "P53314-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53314", "url": "https://www.uniprot.org/uniprotkb/P53314" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 239, "chemical_mass": 26732.0, "gene_names": "CPD1;CPD1", "protein_name": "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "disease": [], "molecular_function": [ { "name": "2',3'-cyclic-nucleotide 3'-phosphodiesterase activity", "id": "GO:0004113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004113", "evidence": [ { "database": "UniProtKB", "id": "P53314", "url": "https://www.uniprot.org/uniprotkb/P53314" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P53314", "url": "https://www.uniprot.org/uniprotkb/P53314" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "P53314", "url": "https://www.uniprot.org/uniprotkb/P53314" } ], "pmid": "" } ], "biological_process": [ { "name": "cyclic nucleotide metabolic process", "id": "GO:0009187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009187", "evidence": [ { "database": "UniProtKB", "id": "P53314", "url": "https://www.uniprot.org/uniprotkb/P53314" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53314-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Ser190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003479", "url": "https://www.yeastgenome.org/locus/S000003479" }, { "database": "iPTMnet", "id": "P53314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53314-1", "start_pos": "150", "end_pos": "150", "site_lbl": "His150", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes cyclic nucleotide phosphodiesterase activity.", "evidence": [ { "database": "UniProtKB", "id": "P53314", "url": "https://www.uniprot.org/uniprotkb/P53314" }, { "database": "PubMed", "id": "10734185", "url": "https://glygen.org/publication/PubMed/10734185" } ] } ] }, { "uniprot_canonical_ac": "P53314-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Ser152", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Strongly reduces cyclic nucleotide phosphodiesterase activity.", "evidence": [ { "database": "UniProtKB", "id": "P53314", "url": "https://www.uniprot.org/uniprotkb/P53314" }, { "database": "PubMed", "id": "10734185", "url": "https://glygen.org/publication/PubMed/10734185" } ] } ] }, { "uniprot_canonical_ac": "P53314-1", "start_pos": "39", "end_pos": "39", "site_lbl": "His39", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes cyclic nucleotide phosphodiesterase activity.", "evidence": [ { "database": "UniProtKB", "id": "P53314", "url": "https://www.uniprot.org/uniprotkb/P53314" }, { "database": "PubMed", "id": "10734185", "url": "https://glygen.org/publication/PubMed/10734185" } ] } ] }, { "uniprot_canonical_ac": "P53314-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Thr41", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Strongly reduces cyclic nucleotide phosphodiesterase activity.", "evidence": [ { "database": "UniProtKB", "id": "P53314", "url": "https://www.uniprot.org/uniprotkb/P53314" }, { "database": "PubMed", "id": "10734185", "url": "https://glygen.org/publication/PubMed/10734185" } ] } ] } ], "record_id": "P53314-1" }, { "uniprot_canonical_ac": "P53324-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53324", "url": "https://www.uniprot.org/uniprotkb/P53324" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 424, "chemical_mass": 48541.0, "gene_names": "SAY1;SAY1", "protein_name": "Steryl acetyl hydrolase 1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53324", "url": "https://www.uniprot.org/uniprotkb/P53324" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "P53324", "url": "https://www.uniprot.org/uniprotkb/P53324" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P53324", "url": "https://www.uniprot.org/uniprotkb/P53324" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P53324", "url": "https://www.uniprot.org/uniprotkb/P53324" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53324", "url": "https://www.uniprot.org/uniprotkb/P53324" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P53324", "url": "https://www.uniprot.org/uniprotkb/P53324" } ], "pmid": "" } ], "biological_process": [ { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "P53324", "url": "https://www.uniprot.org/uniprotkb/P53324" } ], "pmid": "" }, { "name": "sterol metabolic process", "id": "GO:0016125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016125", "evidence": [ { "database": "UniProtKB", "id": "P53324", "url": "https://www.uniprot.org/uniprotkb/P53324" } ], "pmid": "" } ], "molecular_function": [ { "name": "steryl deacetylase activity", "id": "GO:0034084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034084", "evidence": [ { "database": "UniProtKB", "id": "P53324", "url": "https://www.uniprot.org/uniprotkb/P53324" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53324-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Asn283", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 283, "start_aa": "Asn", "end_pos": 283, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn283", "evidence": [ { "id": "P53324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53324#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53324-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Asn401", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 401, "start_aa": "Asn", "end_pos": 401, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn401", "evidence": [ { "id": "P53324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53324#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53324-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Asn85", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 85, "start_aa": "Asn", "end_pos": 85, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn85", "evidence": [ { "id": "P53324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53324#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53324-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003495", "url": "https://www.yeastgenome.org/locus/S000003495" }, { "database": "iPTMnet", "id": "P53324", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53324" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53324-1" }, { "uniprot_canonical_ac": "P53327-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1967, "chemical_mass": 224850.0, "gene_names": "SLH1;G9365;RQT2;SLH1", "protein_name": "RQC trigger complex helicase SLH1", "disease": [ { "disease_id": "DOID:0060308", "name": "autosomal recessive intellectual developmental disorder", "description": "A intellectual disability characterized by an autosomal recessive inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0060308", "evidence": [ { "id": "0060308", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060308" } ], "weight": 0.0 } ], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "ribosome-associated ubiquitin-dependent protein catabolic process", "id": "GO:1990116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990116", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53327-1", "start_pos": "1210", "end_pos": "1210", "site_lbl": "Thr1210", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003503", "url": "https://www.yeastgenome.org/locus/S000003503" }, { "database": "iPTMnet", "id": "P53327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53327" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53327-1", "start_pos": "1213", "end_pos": "1213", "site_lbl": "Thr1213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003503", "url": "https://www.yeastgenome.org/locus/S000003503" }, { "database": "iPTMnet", "id": "P53327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53327" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53327-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Thr178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003503", "url": "https://www.yeastgenome.org/locus/S000003503" }, { "database": "iPTMnet", "id": "P53327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53327-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Thr317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53327" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53327-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Thr408", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53327" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53327-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Ser419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53327" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53327-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Lys316", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes splitting of stalled ribosomes. Defective activation of the ribosome quality control (RQC) pathway. Does not affect the association of the RQT complex with ribosomes.", "evidence": [ { "database": "UniProtKB", "id": "P53327", "url": "https://www.uniprot.org/uniprotkb/P53327" }, { "database": "PubMed", "id": "32203490", "url": "https://glygen.org/publication/PubMed/32203490" }, { "database": "PubMed", "id": "28757607", "url": "https://glygen.org/publication/PubMed/28757607" }, { "database": "PubMed", "id": "30893611", "url": "https://glygen.org/publication/PubMed/30893611" } ] } ] } ], "record_id": "P53327-1" }, { "uniprot_canonical_ac": "P53334-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 386, "chemical_mass": 40173.0, "gene_names": "SCW4;SCW4", "protein_name": "Probable family 17 glucosidase SCW4", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" }, { "name": "glucosidase activity", "id": "GO:0015926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015926", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" }, { "name": "glucan endo-1,3-beta-D-glucosidase activity", "id": "GO:0042973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042973", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" }, { "name": "conjugation with cellular fusion", "id": "GO:0000747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000747", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "P53334", "url": "https://www.uniprot.org/uniprotkb/P53334" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53334-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Thr235", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 235, "start_aa": "Thr", "end_pos": 235, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr235", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P53334-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Asn89", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 89, "start_aa": "Asn", "end_pos": 89, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn89", "evidence": [ { "id": "P53334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53334#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53334-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Thr137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53334" }, { "database": "PubMed", "id": "33167499", "url": "https://glygen.org/publication/PubMed/33167499" } ] } ] } ], "record_id": "P53334-1" }, { "uniprot_canonical_ac": "P53337-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53337", "url": "https://www.uniprot.org/uniprotkb/P53337" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 310, "chemical_mass": 35013.0, "gene_names": "ERV29;ERV29", "protein_name": "ER-derived vesicles protein ERV29", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53337", "url": "https://www.uniprot.org/uniprotkb/P53337" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "P53337", "url": "https://www.uniprot.org/uniprotkb/P53337" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53337", "url": "https://www.uniprot.org/uniprotkb/P53337" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "P53337", "url": "https://www.uniprot.org/uniprotkb/P53337" } ], "pmid": "" } ], "biological_process": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P53337", "url": "https://www.uniprot.org/uniprotkb/P53337" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "P53337", "url": "https://www.uniprot.org/uniprotkb/P53337" } ], "pmid": "" } ], "molecular_function": [ { "name": "COPII receptor activity", "id": "GO:0097020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097020", "evidence": [ { "database": "UniProtKB", "id": "P53337", "url": "https://www.uniprot.org/uniprotkb/P53337" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53337-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003516", "url": "https://www.yeastgenome.org/locus/S000003516" }, { "database": "iPTMnet", "id": "P53337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53337" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53337-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003516", "url": "https://www.yeastgenome.org/locus/S000003516" }, { "database": "iPTMnet", "id": "P53337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53337" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53337-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Tyr22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003516", "url": "https://www.yeastgenome.org/locus/S000003516" }, { "database": "iPTMnet", "id": "P53337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53337" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53337-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003516", "url": "https://www.yeastgenome.org/locus/S000003516" }, { "database": "iPTMnet", "id": "P53337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53337" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53337-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003516", "url": "https://www.yeastgenome.org/locus/S000003516" }, { "database": "iPTMnet", "id": "P53337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53337" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P53337-1" }, { "uniprot_canonical_ac": "P53378-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 473, "chemical_mass": 52627.0, "gene_names": "TUB4;L8167.21;TUB4", "protein_name": "Tubulin gamma chain", "disease": [ { "disease_id": "DOID:0080000", "name": "muscular disease", "description": "A musculoskeletal system disease that affects the muscles.", "url": "https://disease-ontology.org/term/DOID:0080000", "evidence": [ { "id": "0080000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080000" } ], "weight": 0.0 }, { "disease_id": "DOID:0090138", "name": "complex cortical dysplasia with other brain malformations 4", "description": "A complex cortical dysplasia with other brain malformations that has_material_basis_in autosomal dominant inheritance of heterozygous mutation in the tubulin gamma 1 gene on chromosome 17q21.", "url": "https://disease-ontology.org/term/DOID:0090138", "evidence": [ { "id": "0090138", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090138" } ], "weight": 0.0 }, { "disease_id": "DOID:3429", "name": "inclusion body myositis", "description": "A myositis that is characterized by late onset of skeletal muscle inflammation, weakness, and atrophy with cytoplasmic granules and vacuoles in the muscle.", "url": "https://disease-ontology.org/term/DOID:3429", "evidence": [ { "id": "3429", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3429" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "gamma-tubulin small complex", "id": "GO:0008275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008275", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "gamma-tubulin ring complex", "id": "GO:0000931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000931", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "inner plaque of spindle pole body", "id": "GO:0005822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005822", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "outer plaque of spindle pole body", "id": "GO:0005824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005824", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cytoplasmic translation", "id": "GO:2000767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000767", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "regulation of microtubule nucleation", "id": "GO:0010968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010968", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "meiotic spindle organization", "id": "GO:0000212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000212", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "microtubule nucleation by spindle pole body", "id": "GO:0051417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051417", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" }, { "name": "microtubule nucleator activity", "id": "GO:0140490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140490", "evidence": [ { "database": "UniProtKB", "id": "P53378", "url": "https://www.uniprot.org/uniprotkb/P53378" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53378-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Ser100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53378" }, { "database": "PubMed", "id": "21573187", "url": "https://glygen.org/publication/PubMed/21573187" } ] } ] }, { "uniprot_canonical_ac": "P53378-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Ser360", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53378" }, { "database": "PubMed", "id": "21573187", "url": "https://glygen.org/publication/PubMed/21573187" } ] } ] }, { "uniprot_canonical_ac": "P53378-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Tyr362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004202", "url": "https://www.yeastgenome.org/locus/S000004202" }, { "database": "iPTMnet", "id": "P53378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53378" }, { "database": "PubMed", "id": "28900268", "url": "https://glygen.org/publication/PubMed/28900268" } ] } ] }, { "uniprot_canonical_ac": "P53378-1", "start_pos": "415", "end_pos": "415", "site_lbl": "Ser415", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53378" }, { "database": "PubMed", "id": "21573187", "url": "https://glygen.org/publication/PubMed/21573187" } ] } ] }, { "uniprot_canonical_ac": "P53378-1", "start_pos": "445", "end_pos": "445", "site_lbl": "Tyr445", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53378" }, { "database": "PubMed", "id": "11709183", "url": "https://glygen.org/publication/PubMed/11709183" } ] } ] }, { "uniprot_canonical_ac": "P53378-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004202", "url": "https://www.yeastgenome.org/locus/S000004202" }, { "database": "iPTMnet", "id": "P53378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53378" }, { "database": "PubMed", "id": "29903865", "url": "https://glygen.org/publication/PubMed/29903865" } ] } ] }, { "uniprot_canonical_ac": "P53378-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53378" }, { "database": "PubMed", "id": "21573187", "url": "https://glygen.org/publication/PubMed/21573187" } ] } ] } ], "record_id": "P53378-1" }, { "uniprot_canonical_ac": "P53379-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53379", "url": "https://www.uniprot.org/uniprotkb/P53379" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 596, "chemical_mass": 64269.0, "gene_names": "MKC7;MKC7;YD2943.03C;YD8358.01C;YPS2", "protein_name": "Aspartic proteinase MKC7", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P53379", "url": "https://www.uniprot.org/uniprotkb/P53379" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53379", "url": "https://www.uniprot.org/uniprotkb/P53379" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P53379", "url": "https://www.uniprot.org/uniprotkb/P53379" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P53379", "url": "https://www.uniprot.org/uniprotkb/P53379" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P53379", "url": "https://www.uniprot.org/uniprotkb/P53379" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "P53379", "url": "https://www.uniprot.org/uniprotkb/P53379" } ], "pmid": "" }, { "name": "signal transduction involved in filamentous growth", "id": "GO:0001402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001402", "evidence": [ { "database": "UniProtKB", "id": "P53379", "url": "https://www.uniprot.org/uniprotkb/P53379" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P53379", "url": "https://www.uniprot.org/uniprotkb/P53379" } ], "pmid": "" } ], "molecular_function": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "P53379", "url": "https://www.uniprot.org/uniprotkb/P53379" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53379-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Asn180", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 180, "start_aa": "Asn", "end_pos": 180, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn180", "evidence": [ { "id": "P53379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53379#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53379-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Asn190", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 190, "start_aa": "Asn", "end_pos": 190, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn190", "evidence": [ { "id": "P53379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53379#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53379-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Asn219", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 219, "start_aa": "Asn", "end_pos": 219, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn219", "evidence": [ { "id": "P53379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53379#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53379-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Asn229", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 229, "start_aa": "Asn", "end_pos": 229, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn229", "evidence": [ { "id": "P53379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53379#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53379-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Asn232", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 232, "start_aa": "Asn", "end_pos": 232, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn232", "evidence": [ { "id": "P53379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53379#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53379-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Asn286", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "P53379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53379#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53379-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Asn346", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 346, "start_aa": "Asn", "end_pos": 346, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn346", "evidence": [ { "id": "P53379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53379#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53379-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Asn471", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 471, "start_aa": "Asn", "end_pos": 471, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn471", "evidence": [ { "id": "P53379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53379#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53379-1", "start_pos": "517", "end_pos": "517", "site_lbl": "Asn517", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 517, "start_aa": "Asn", "end_pos": 517, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn517", "evidence": [ { "id": "P53379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53379#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53379-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Ser278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53379" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002551", "url": "https://www.yeastgenome.org/locus/S000002551" } ] } ] }, { "uniprot_canonical_ac": "P53379-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Thr279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53379" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002551", "url": "https://www.yeastgenome.org/locus/S000002551" } ] } ] } ], "record_id": "P53379-1" }, { "uniprot_canonical_ac": "P53397-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 376, "chemical_mass": 42781.0, "gene_names": "OGG1;OGG1;YM9958.02", "protein_name": "N-glycosylase/DNA lyase", "disease": [ { "disease_id": "DOID:0002116", "name": "pterygium", "description": "A corneal disease that is characterized by a triangular tissue growth located_in cornea of the eye that is the result of collagen degeneration and fibrovascular proliferation.", "url": "https://disease-ontology.org/term/DOID:0002116", "evidence": [ { "id": "0002116", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0002116" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:1070", "name": "primary open angle glaucoma", "description": "An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure.", "url": "https://disease-ontology.org/term/DOID:1070", "evidence": [ { "id": "1070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1070" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11714", "name": "gestational diabetes", "description": "A diabetes mellitus that manifests during pregnancy.", "url": "https://disease-ontology.org/term/DOID:11714", "evidence": [ { "id": "11714", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11714" } ], "weight": 0.0 }, { "disease_id": "DOID:12361", "name": "Graves' disease", "description": "An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.", "url": "https://disease-ontology.org/term/DOID:12361", "evidence": [ { "id": "12361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12361" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:2237", "name": "hepatitis", "description": "A liver disease that is characterized as an inflammation of the liver.", "url": "https://disease-ontology.org/term/DOID:2237", "evidence": [ { "id": "2237", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2237" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2513", "name": "basal cell carcinoma", "description": "A skin carcinoma affecting basal cells.", "url": "https://disease-ontology.org/term/DOID:2513", "evidence": [ { "id": "2513", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2513" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:3314", "name": "angiomyolipoma", "description": "A cell type benign neoplasm that is primarily located in the kidneys but may be found in the lungs, liver or other organs and is derived from perivascular epithelioid cells.", "url": "https://disease-ontology.org/term/DOID:3314", "evidence": [ { "id": "3314", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3314" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:5520", "name": "head and neck squamous cell carcinoma", "description": "A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck.", "url": "https://disease-ontology.org/term/DOID:5520", "evidence": [ { "id": "5520", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5520" } ], "weight": 0.0 }, { "disease_id": "DOID:678", "name": "progressive supranuclear palsy", "description": "A movement disease that is characterized by serious and progressive problems with control of gait and balance, along with complex eye movement and thinking problems. It involves gradual deterioration and death of specific volumes of the brain.", "url": "https://disease-ontology.org/term/DOID:678", "evidence": [ { "id": "678", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:678" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9669", "name": "senile cataract", "description": "A cataract that is characterized by thickening and loss of transparency of the lens with age progression, caused by a multifactorial etiology related to aging.", "url": "https://disease-ontology.org/term/DOID:9669", "evidence": [ { "id": "9669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9669" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "8-oxo-7,8-dihydroguanine DNA N-glycosylase activity", "id": "GO:0034039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034039", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" }, { "name": "class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0140078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140078", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" }, { "name": "oxidized purine nucleobase lesion DNA N-glycosylase activity", "id": "GO:0008534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008534", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" }, { "name": "telomere maintenance via telomerase", "id": "GO:0007004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007004", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" }, { "name": "base-excision repair, AP site formation", "id": "GO:0006285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006285", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" }, { "name": "error-free translesion synthesis", "id": "GO:0070987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070987", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53397-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004525", "url": "https://www.yeastgenome.org/locus/S000004525" }, { "database": "iPTMnet", "id": "P53397", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53397" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53397-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Ser293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004525", "url": "https://www.yeastgenome.org/locus/S000004525" }, { "database": "iPTMnet", "id": "P53397", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53397" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53397-1", "start_pos": "366", "end_pos": "366", "site_lbl": "Ser366", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004525", "url": "https://www.yeastgenome.org/locus/S000004525" }, { "database": "iPTMnet", "id": "P53397", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53397" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53397-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004525", "url": "https://www.yeastgenome.org/locus/S000004525" }, { "database": "iPTMnet", "id": "P53397", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53397" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53397-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Thr40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004525", "url": "https://www.yeastgenome.org/locus/S000004525" }, { "database": "iPTMnet", "id": "P53397", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53397" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53397-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Thr41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004525", "url": "https://www.yeastgenome.org/locus/S000004525" }, { "database": "iPTMnet", "id": "P53397", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53397" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53397-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Lys241", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "Q", "comment": "Abolishes both DNA glycosylase and AP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" }, { "database": "PubMed", "id": "9241232", "url": "https://glygen.org/publication/PubMed/9241232" }, { "database": "PubMed", "id": "10677220", "url": "https://glygen.org/publication/PubMed/10677220" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Diminishes both DNA glycosylase and AP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P53397", "url": "https://www.uniprot.org/uniprotkb/P53397" }, { "database": "PubMed", "id": "9241232", "url": "https://glygen.org/publication/PubMed/9241232" }, { "database": "PubMed", "id": "10677220", "url": "https://glygen.org/publication/PubMed/10677220" } ] } ] } ], "record_id": "P53397-1" }, { "uniprot_canonical_ac": "P53507-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53507", "url": "https://www.uniprot.org/uniprotkb/P53507" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 60, "chemical_mass": 6870.0, "gene_names": "TOM7;MOM7;N2378;TOM7;YOK22", "protein_name": "Mitochondrial import receptor subunit TOM7", "disease": [], "biological_process": [ { "name": "protein insertion into mitochondrial outer membrane", "id": "GO:0045040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045040", "evidence": [ { "database": "UniProtKB", "id": "P53507", "url": "https://www.uniprot.org/uniprotkb/P53507" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "P53507", "url": "https://www.uniprot.org/uniprotkb/P53507" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53507", "url": "https://www.uniprot.org/uniprotkb/P53507" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P53507", "url": "https://www.uniprot.org/uniprotkb/P53507" } ], "pmid": "" }, { "name": "mitochondrial outer membrane translocase complex", "id": "GO:0005742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005742", "evidence": [ { "database": "UniProtKB", "id": "P53507", "url": "https://www.uniprot.org/uniprotkb/P53507" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53507-1" }, { "uniprot_canonical_ac": "P53538-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 206, "chemical_mass": 23469.0, "gene_names": "SSU72;N1279;SSU72", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "disease": [ { "disease_id": "DOID:409", "name": "liver disease", "description": "", "url": "https://disease-ontology.org/term/DOID:409", "evidence": [ { "id": "409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:409" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "RNA polymerase II CTD heptapeptide repeat phosphatase activity", "id": "GO:0008420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008420", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" } ], "biological_process": [ { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription", "id": "GO:0006369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006369", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "transcriptional start site selection at RNA polymerase II promoter", "id": "GO:0001174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001174", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "sno(s)RNA transcription", "id": "GO:0009302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009302", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription, poly(A)-coupled", "id": "GO:0030846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030846", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription, exosome-dependent", "id": "GO:0030847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030847", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" }, { "name": "transcription antitermination", "id": "GO:0031564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031564", "evidence": [ { "database": "UniProtKB", "id": "P53538", "url": "https://www.uniprot.org/uniprotkb/P53538" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53538-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Thr41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53538", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53538" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005166", "url": "https://www.yeastgenome.org/locus/S000005166" } ] } ] }, { "uniprot_canonical_ac": "P53538-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53538", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53538" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005166", "url": "https://www.yeastgenome.org/locus/S000005166" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53538-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Tyr68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53538", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53538" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005166", "url": "https://www.yeastgenome.org/locus/S000005166" } ] } ] }, { "uniprot_canonical_ac": "P53538-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005166", "url": "https://www.yeastgenome.org/locus/S000005166" }, { "database": "iPTMnet", "id": "P53538", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53538" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53538-1" }, { "uniprot_canonical_ac": "P53540-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 846, "chemical_mass": 98227.0, "gene_names": "SPC98;N1222;N1879;SPC98", "protein_name": "Spindle pole body component SPC98", "disease": [], "cellular_component": [ { "name": "gamma-tubulin small complex", "id": "GO:0008275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008275", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "gamma-tubulin complex", "id": "GO:0000930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000930", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "inner plaque of spindle pole body", "id": "GO:0005822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005822", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "outer plaque of spindle pole body", "id": "GO:0005824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005824", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of microtubule nucleation", "id": "GO:0010968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010968", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" } ], "molecular_function": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53540-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53540", "url": "https://www.uniprot.org/uniprotkb/P53540" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Ser152", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29903865", "url": "https://glygen.org/publication/PubMed/29903865" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ser159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Thr161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Tyr162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Ser163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Ser531", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53540-1", "start_pos": "814", "end_pos": "814", "site_lbl": "Ser814", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005070", "url": "https://www.yeastgenome.org/locus/S000005070" }, { "database": "iPTMnet", "id": "P53540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53540" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53540-1" }, { "uniprot_canonical_ac": "P53541-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 631, "chemical_mass": 72187.0, "gene_names": "SPO1;N2858;SPO1", "protein_name": "Putative meiotic phospholipase SPO1", "disease": [ { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:2615", "name": "papilloma", "description": "A cell type benign neoplam that is composed of epithelial tissue on papillae of vascularized connective tissue.", "url": "https://disease-ontology.org/term/DOID:2615", "evidence": [ { "id": "2615", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2615" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" } ], "molecular_function": [ { "name": "phospholipase activity", "id": "GO:0004620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004620", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" } ], "biological_process": [ { "name": "glycerophospholipid catabolic process", "id": "GO:0046475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046475", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "meiosis I", "id": "GO:0007127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007127", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "spindle pole body duplication", "id": "GO:0030474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030474", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "ascospore-type prospore membrane formation", "id": "GO:0032120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032120", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" }, { "name": "spore membrane bending pathway", "id": "GO:0070583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070583", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53541-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Asn233", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 233, "start_aa": "Asn", "end_pos": 233, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn233", "evidence": [ { "id": "P53541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53541#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53541-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Asn293", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 293, "start_aa": "Asn", "end_pos": 293, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn293", "evidence": [ { "id": "P53541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53541#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53541-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Asn303", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 303, "start_aa": "Asn", "end_pos": 303, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn303", "evidence": [ { "id": "P53541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53541#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53541-1", "start_pos": "500", "end_pos": "500", "site_lbl": "Asn500", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 500, "start_aa": "Asn", "end_pos": 500, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn500", "evidence": [ { "id": "P53541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53541#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53541-1", "start_pos": "536", "end_pos": "536", "site_lbl": "Asn536", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 536, "start_aa": "Asn", "end_pos": 536, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn536", "evidence": [ { "id": "P53541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53541#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53541-1", "start_pos": "560", "end_pos": "560", "site_lbl": "Asn560", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 560, "start_aa": "Asn", "end_pos": 560, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn560", "evidence": [ { "id": "P53541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53541#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53541-1", "start_pos": "563", "end_pos": "563", "site_lbl": "Asn563", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 563, "start_aa": "Asn", "end_pos": 563, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn563", "evidence": [ { "id": "P53541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53541#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53541-1", "start_pos": "572", "end_pos": "572", "site_lbl": "Asn572", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 572, "start_aa": "Asn", "end_pos": 572, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn572", "evidence": [ { "id": "P53541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53541#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53541-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ile103", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "F", "comment": "In SPO1-1; defective in sporulation at 34 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" }, { "database": "PubMed", "id": "10855497", "url": "https://glygen.org/publication/PubMed/10855497" } ] } ] }, { "uniprot_canonical_ac": "P53541-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P53541", "url": "https://www.uniprot.org/uniprotkb/P53541" }, { "database": "PubMed", "id": "10855497", "url": "https://glygen.org/publication/PubMed/10855497" } ] } ] } ], "record_id": "P53541-1" }, { "uniprot_canonical_ac": "P53551-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 258, "chemical_mass": 27804.0, "gene_names": "HHO1;HHO1;LPI17C", "protein_name": "Histone H1", "disease": [ { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phosphate ion binding", "id": "GO:0042301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042301", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "nucleosomal DNA binding", "id": "GO:0031492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031492", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "supercoiled DNA binding", "id": "GO:0097100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097100", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "protein-DNA complex", "id": "GO:0032993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032993", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "chromosome condensation", "id": "GO:0030261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030261", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "negative regulation of DNA recombination", "id": "GO:0045910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045910", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "regulation of double-strand break repair", "id": "GO:2000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000779", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" }, { "name": "sporulation", "id": "GO:0043934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043934", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53551-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53551", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53551" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006048", "url": "https://www.yeastgenome.org/locus/S000006048" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P53551-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006048", "url": "https://www.yeastgenome.org/locus/S000006048" }, { "database": "iPTMnet", "id": "P53551", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53551" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53551-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ser164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006048", "url": "https://www.yeastgenome.org/locus/S000006048" }, { "database": "iPTMnet", "id": "P53551", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53551" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53551-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Ser173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53551", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53551" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006048", "url": "https://www.yeastgenome.org/locus/S000006048" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "31821952", "url": "https://glygen.org/publication/PubMed/31821952" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53551-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53551", "url": "https://www.uniprot.org/uniprotkb/P53551" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P53551", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53551" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006048", "url": "https://www.yeastgenome.org/locus/S000006048" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "31821952", "url": "https://glygen.org/publication/PubMed/31821952" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53551-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006048", "url": "https://www.yeastgenome.org/locus/S000006048" }, { "database": "iPTMnet", "id": "P53551", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53551" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53551-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53551", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53551" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006048", "url": "https://www.yeastgenome.org/locus/S000006048" } ] } ] }, { "uniprot_canonical_ac": "P53551-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Tyr222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006048", "url": "https://www.yeastgenome.org/locus/S000006048" }, { "database": "iPTMnet", "id": "P53551", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53551" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53551-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006048", "url": "https://www.yeastgenome.org/locus/S000006048" }, { "database": "iPTMnet", "id": "P53551", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53551" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53551-1" }, { "uniprot_canonical_ac": "P53552-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1597, "chemical_mass": 183931.0, "gene_names": "THO2;LDB5;N1209;N1835;RLR1;THO2;ZRG13", "protein_name": "THO complex subunit 2", "disease": [ { "disease_id": "DOID:0112056", "name": "X-linked intellectual disability-short stature-overweight syndrome", "description": "A syndromic X-linked intellectual disability characterized by borderline to severe intellectual disability often associated with speech delay, short stature, elevated body mass index, and a truncal obesity pattern in older males that has_material_basis_in hemizygous mutation in the THOC2 gene on chromosome Xq25.", "url": "https://disease-ontology.org/term/DOID:0112056", "evidence": [ { "id": "0112056", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112056" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "THO complex part of transcription export complex", "id": "GO:0000445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000445", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "nucleoplasmic THO complex", "id": "GO:0000446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000446", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "transcription-coupled nucleotide-excision repair", "id": "GO:0006283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006283", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "cellular response to azide", "id": "GO:0097185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097185", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase I", "id": "GO:2001209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001209", "evidence": [ { "database": "UniProtKB", "id": "P53552", "url": "https://www.uniprot.org/uniprotkb/P53552" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53552-1", "start_pos": "1261", "end_pos": "1261", "site_lbl": "Ser1261", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1261, "start_aa": "Ser", "end_pos": 1261, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1261", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53552", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53552" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1264", "end_pos": "1264", "site_lbl": "Ser1264", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1264, "start_aa": "Ser", "end_pos": 1264, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1264", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53552", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53552" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1266", "end_pos": "1266", "site_lbl": "Ser1266", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1266, "start_aa": "Ser", "end_pos": 1266, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1266", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53552", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53552" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1271", "end_pos": "1271", "site_lbl": "Ser1271", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1271, "start_aa": "Ser", "end_pos": 1271, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1271", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53552", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53552" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1294", "end_pos": "1294", "site_lbl": "Ser1294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1319", "end_pos": "1319", "site_lbl": "Ser1319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1386", "end_pos": "1386", "site_lbl": "Tyr1386", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1389", "end_pos": "1389", "site_lbl": "Thr1389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1391", "end_pos": "1391", "site_lbl": "Ser1391", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1392", "end_pos": "1392", "site_lbl": "Ser1392", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1394", "end_pos": "1394", "site_lbl": "Ser1394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1526", "end_pos": "1526", "site_lbl": "Ser1526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "1528", "end_pos": "1528", "site_lbl": "Ser1528", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Thr361", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Ser647", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "650", "end_pos": "650", "site_lbl": "Thr650", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "797", "end_pos": "797", "site_lbl": "Ser797", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53552-1", "start_pos": "979", "end_pos": "979", "site_lbl": "Ser979", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005083", "url": "https://www.yeastgenome.org/locus/S000005083" }, { "database": "iPTMnet", "id": "P53552", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53552" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53552-1" }, { "uniprot_canonical_ac": "P53598-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53598", "url": "https://www.uniprot.org/uniprotkb/P53598" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 329, "chemical_mass": 35032.0, "gene_names": "LSC1;LSC1;YOR3352W", "protein_name": "Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial", "disease": [ { "disease_id": "DOID:0080128", "name": "mitochondrial DNA depletion syndrome 9", "description": "A mitochondrial DNA depletion syndrome that is characterized by infantile onset of hypotonia, lactic acidosis, severe psychomotor retardation, progressive neurologic deterioration, and excretion of methylmalonic acid, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the alpha subunit of the succinate-CoA ligase gene on chromosome 2p11.", "url": "https://disease-ontology.org/term/DOID:0080128", "evidence": [ { "id": "0080128", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080128" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53598", "url": "https://www.uniprot.org/uniprotkb/P53598" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "P53598", "url": "https://www.uniprot.org/uniprotkb/P53598" } ], "pmid": "" }, { "name": "succinate-CoA ligase complex (ADP-forming)", "id": "GO:0009361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009361", "evidence": [ { "database": "UniProtKB", "id": "P53598", "url": "https://www.uniprot.org/uniprotkb/P53598" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "P53598", "url": "https://www.uniprot.org/uniprotkb/P53598" } ], "pmid": "" }, { "name": "succinyl-CoA metabolic process", "id": "GO:0006104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006104", "evidence": [ { "database": "UniProtKB", "id": "P53598", "url": "https://www.uniprot.org/uniprotkb/P53598" } ], "pmid": "" }, { "name": "succinyl-CoA catabolic process", "id": "GO:1901289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901289", "evidence": [ { "database": "UniProtKB", "id": "P53598", "url": "https://www.uniprot.org/uniprotkb/P53598" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "P53598", "url": "https://www.uniprot.org/uniprotkb/P53598" } ], "pmid": "" }, { "name": "succinate-CoA ligase (ADP-forming) activity", "id": "GO:0004775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004775", "evidence": [ { "database": "UniProtKB", "id": "P53598", "url": "https://www.uniprot.org/uniprotkb/P53598" } ], "pmid": "" }, { "name": "succinate-CoA ligase (GDP-forming) activity", "id": "GO:0004776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004776", "evidence": [ { "database": "UniProtKB", "id": "P53598", "url": "https://www.uniprot.org/uniprotkb/P53598" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53598-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53598", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53598" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "SGD", "id": "S000005668", "url": "https://www.yeastgenome.org/locus/S000005668" } ] } ] }, { "uniprot_canonical_ac": "P53598-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Thr186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53598", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53598" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005668", "url": "https://www.yeastgenome.org/locus/S000005668" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53598-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005668", "url": "https://www.yeastgenome.org/locus/S000005668" }, { "database": "iPTMnet", "id": "P53598", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53598" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53598-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Ser260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005668", "url": "https://www.yeastgenome.org/locus/S000005668" }, { "database": "iPTMnet", "id": "P53598", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53598" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53598-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005668", "url": "https://www.yeastgenome.org/locus/S000005668" }, { "database": "iPTMnet", "id": "P53598", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53598" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53598-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005668", "url": "https://www.yeastgenome.org/locus/S000005668" }, { "database": "iPTMnet", "id": "P53598", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53598" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53598-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Thr294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005668", "url": "https://www.yeastgenome.org/locus/S000005668" }, { "database": "iPTMnet", "id": "P53598", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53598" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53598-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005668", "url": "https://www.yeastgenome.org/locus/S000005668" }, { "database": "iPTMnet", "id": "P53598", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53598" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53598-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Thr45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005668", "url": "https://www.yeastgenome.org/locus/S000005668" }, { "database": "iPTMnet", "id": "P53598", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53598" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53598-1" }, { "uniprot_canonical_ac": "P53599-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1579, "chemical_mass": 180528.0, "gene_names": "SSK2;N3276;SSK2", "protein_name": "MAP kinase kinase kinase SSK2", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "stress-activated MAPK cascade", "id": "GO:0051403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051403", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "cellular hyperosmotic response", "id": "GO:0071474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071474", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" }, { "name": "osmosensory signaling via phosphorelay pathway", "id": "GO:0007234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007234", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53599-1", "start_pos": "1063", "end_pos": "1063", "site_lbl": "Tyr1063", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1068", "end_pos": "1068", "site_lbl": "Thr1068", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1069", "end_pos": "1069", "site_lbl": "Thr1069", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1276", "end_pos": "1276", "site_lbl": "Thr1276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1282", "end_pos": "1282", "site_lbl": "Ser1282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Ser131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1420", "end_pos": "1420", "site_lbl": "Thr1420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "9482735", "url": "https://glygen.org/publication/PubMed/9482735" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1424", "end_pos": "1424", "site_lbl": "Ser1424", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1442", "end_pos": "1442", "site_lbl": "Ser1442", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1460", "end_pos": "1460", "site_lbl": "Thr1460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1570", "end_pos": "1570", "site_lbl": "Ser1570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1571", "end_pos": "1571", "site_lbl": "Ser1571", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1572", "end_pos": "1572", "site_lbl": "Ser1572", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1573", "end_pos": "1573", "site_lbl": "Thr1573", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "1575", "end_pos": "1575", "site_lbl": "Thr1575", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Thr174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Ser178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "234", "end_pos": "234", "site_lbl": "Ser234", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Ser241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Ser290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Ser54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "25734609", "url": "https://glygen.org/publication/PubMed/25734609" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "25734609", "url": "https://glygen.org/publication/PubMed/25734609" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Ser62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "651", "end_pos": "651", "site_lbl": "Thr651", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Tyr73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "25734609", "url": "https://glygen.org/publication/PubMed/25734609" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "775", "end_pos": "775", "site_lbl": "Thr775", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53599", "url": "https://www.uniprot.org/uniprotkb/P53599" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "25734609", "url": "https://glygen.org/publication/PubMed/25734609" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53599-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Thr82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53599" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005314", "url": "https://www.yeastgenome.org/locus/S000005314" } ] } ] } ], "record_id": "P53599-1" }, { "uniprot_canonical_ac": "P53615-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53615", "url": "https://www.uniprot.org/uniprotkb/P53615" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 221, "chemical_mass": 24859.0, "gene_names": "NCE103;N2695;NCE103;NCE3", "protein_name": "Carbonic anhydrase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53615", "url": "https://www.uniprot.org/uniprotkb/P53615" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53615", "url": "https://www.uniprot.org/uniprotkb/P53615" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P53615", "url": "https://www.uniprot.org/uniprotkb/P53615" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P53615", "url": "https://www.uniprot.org/uniprotkb/P53615" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "P53615", "url": "https://www.uniprot.org/uniprotkb/P53615" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P53615", "url": "https://www.uniprot.org/uniprotkb/P53615" } ], "pmid": "" }, { "name": "cellular response to carbon dioxide", "id": "GO:0071244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071244", "evidence": [ { "database": "UniProtKB", "id": "P53615", "url": "https://www.uniprot.org/uniprotkb/P53615" } ], "pmid": "" }, { "name": "carbon utilization", "id": "GO:0015976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015976", "evidence": [ { "database": "UniProtKB", "id": "P53615", "url": "https://www.uniprot.org/uniprotkb/P53615" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53615-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004981", "url": "https://www.yeastgenome.org/locus/S000004981" }, { "database": "iPTMnet", "id": "P53615", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53615" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53615-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Thr219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004981", "url": "https://www.yeastgenome.org/locus/S000004981" }, { "database": "iPTMnet", "id": "P53615", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53615" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53615-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004981", "url": "https://www.yeastgenome.org/locus/S000004981" }, { "database": "iPTMnet", "id": "P53615", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53615" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53615-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Thr52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004981", "url": "https://www.yeastgenome.org/locus/S000004981" }, { "database": "iPTMnet", "id": "P53615", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53615" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53615-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004981", "url": "https://www.yeastgenome.org/locus/S000004981" }, { "database": "iPTMnet", "id": "P53615", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53615" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53615-1" }, { "uniprot_canonical_ac": "P53616-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53616", "url": "https://www.uniprot.org/uniprotkb/P53616" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 420, "chemical_mass": 43442.0, "gene_names": "SUN4;N2411;SCW3;SUN4;YNL2411W", "protein_name": "Probable secreted beta-glucosidase SUN4", "disease": [], "cellular_component": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "P53616", "url": "https://www.uniprot.org/uniprotkb/P53616" } ], "pmid": "" }, { "name": "cellular bud scar", "id": "GO:0005621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005621", "evidence": [ { "database": "UniProtKB", "id": "P53616", "url": "https://www.uniprot.org/uniprotkb/P53616" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P53616", "url": "https://www.uniprot.org/uniprotkb/P53616" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "P53616", "url": "https://www.uniprot.org/uniprotkb/P53616" } ], "pmid": "" }, { "name": "polysaccharide catabolic process", "id": "GO:0000272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000272", "evidence": [ { "database": "UniProtKB", "id": "P53616", "url": "https://www.uniprot.org/uniprotkb/P53616" } ], "pmid": "" }, { "name": "division septum assembly", "id": "GO:0000917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000917", "evidence": [ { "database": "UniProtKB", "id": "P53616", "url": "https://www.uniprot.org/uniprotkb/P53616" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P53616", "url": "https://www.uniprot.org/uniprotkb/P53616" } ], "pmid": "" } ], "molecular_function": [ { "name": "glucosidase activity", "id": "GO:0015926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015926", "evidence": [ { "database": "UniProtKB", "id": "P53616", "url": "https://www.uniprot.org/uniprotkb/P53616" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53616-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Asn395", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 395, "start_aa": "Asn", "end_pos": 395, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn395", "evidence": [ { "id": "P53616", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53616#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P53616-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005010", "url": "https://www.yeastgenome.org/locus/S000005010" }, { "database": "iPTMnet", "id": "P53616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53616-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005010", "url": "https://www.yeastgenome.org/locus/S000005010" }, { "database": "iPTMnet", "id": "P53616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53616-1" }, { "uniprot_canonical_ac": "P53685-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 503, "chemical_mass": 57702.0, "gene_names": "HST1;HST1", "protein_name": "NAD-dependent protein deacetylase HST1", "disease": [ { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:11476", "name": "osteoporosis", "description": "A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.", "url": "https://disease-ontology.org/term/DOID:11476", "evidence": [ { "id": "11476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11476" } ], "weight": 0.0 }, { "disease_id": "DOID:12387", "name": "nephrogenic diabetes insipidus", "description": "A diabetes insipidus that is characterized by a complete or partial resistance of the kidneys to vasopressin (ADH).", "url": "https://disease-ontology.org/term/DOID:12387", "evidence": [ { "id": "12387", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12387" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:1875", "name": "impotence", "description": "A sexual dysfunction that is characterized by persistent or recurrent inability to achieve or to maintain an erection during sexual activity.", "url": "https://disease-ontology.org/term/DOID:1875", "evidence": [ { "id": "1875", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1875" } ], "weight": 0.0 }, { "disease_id": "DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries.", "url": "https://disease-ontology.org/term/DOID:1936", "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 }, { "disease_id": "DOID:9669", "name": "senile cataract", "description": "A cataract that is characterized by thickening and loss of transparency of the lens with age progression, caused by a multifactorial etiology related to aging.", "url": "https://disease-ontology.org/term/DOID:9669", "evidence": [ { "id": "9669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9669" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "negative regulation of mitotic recombination", "id": "GO:0045950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045950", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "negative regulation of meiotic nuclear division", "id": "GO:0045835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045835", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "regulation of sporulation", "id": "GO:0043937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043937", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "regulation of thiamine biosynthetic process", "id": "GO:0070623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070623", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone H4K16 deacetylase activity, NAD-dependent", "id": "GO:0046970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046970", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "NAD+ binding", "id": "GO:0070403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070403", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "histone deacetylase activity, NAD-dependent", "id": "GO:0017136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017136", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "histone H3K14 deacetylase activity, NAD-dependent", "id": "GO:0032041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032041", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "histone H3K9 deacetylase activity, NAD-dependent", "id": "GO:0046969", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046969", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" }, { "name": "Set3 complex", "id": "GO:0034967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034967", "evidence": [ { "database": "UniProtKB", "id": "P53685", "url": "https://www.uniprot.org/uniprotkb/P53685" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53685-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005429", "url": "https://www.yeastgenome.org/locus/S000005429" }, { "database": "iPTMnet", "id": "P53685", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53685" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53685-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005429", "url": "https://www.yeastgenome.org/locus/S000005429" }, { "database": "iPTMnet", "id": "P53685", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53685" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53685-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Ser143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005429", "url": "https://www.yeastgenome.org/locus/S000005429" }, { "database": "iPTMnet", "id": "P53685", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53685" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30377154", "url": "https://glygen.org/publication/PubMed/30377154" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53685-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005429", "url": "https://www.yeastgenome.org/locus/S000005429" }, { "database": "iPTMnet", "id": "P53685", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53685" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53685-1" }, { "uniprot_canonical_ac": "P53687-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 447, "chemical_mass": 50524.0, "gene_names": "HST3;HST3;OR26.15", "protein_name": "NAD-dependent histone deacetylase HST3", "disease": [], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" }, { "name": "short-chain fatty acid metabolic process", "id": "GO:0046459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046459", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" }, { "name": "rDNA heterochromatin formation", "id": "GO:0000183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000183", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" }, { "name": "mRNA transcription", "id": "GO:0009299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009299", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" }, { "name": "replication-born double-strand break repair via sister chromatid exchange", "id": "GO:1990414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990414", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" }, { "name": "NAD+ binding", "id": "GO:0070403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070403", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" }, { "name": "histone deacetylase activity, NAD-dependent", "id": "GO:0017136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017136", "evidence": [ { "database": "UniProtKB", "id": "P53687", "url": "https://www.uniprot.org/uniprotkb/P53687" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53687-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005551", "url": "https://www.yeastgenome.org/locus/S000005551" }, { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53687-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005551", "url": "https://www.yeastgenome.org/locus/S000005551" }, { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53687-1", "start_pos": "380", "end_pos": "380", "site_lbl": "Thr380", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "24648511", "url": "https://glygen.org/publication/PubMed/24648511" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005551", "url": "https://www.yeastgenome.org/locus/S000005551" }, { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53687-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Thr383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005551", "url": "https://www.yeastgenome.org/locus/S000005551" }, { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53687-1", "start_pos": "384", "end_pos": "384", "site_lbl": "Thr384", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "24648511", "url": "https://glygen.org/publication/PubMed/24648511" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005551", "url": "https://www.yeastgenome.org/locus/S000005551" }, { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53687-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005551", "url": "https://www.yeastgenome.org/locus/S000005551" }, { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53687-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Ser406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P53687-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Ser416", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005551", "url": "https://www.yeastgenome.org/locus/S000005551" }, { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "21725298", "url": "https://glygen.org/publication/PubMed/21725298" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53687-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005551", "url": "https://www.yeastgenome.org/locus/S000005551" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53687-1", "start_pos": "421", "end_pos": "421", "site_lbl": "Ser421", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005551", "url": "https://www.yeastgenome.org/locus/S000005551" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53687-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005551", "url": "https://www.yeastgenome.org/locus/S000005551" }, { "database": "iPTMnet", "id": "P53687", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53687" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53687-1" }, { "uniprot_canonical_ac": "P53688-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 370, "chemical_mass": 41765.0, "gene_names": "HST4;HST4;YD9346.03", "protein_name": "NAD-dependent histone deacetylase HST4", "disease": [], "biological_process": [ { "name": "pericentric heterochromatin formation", "id": "GO:0031508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031508", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "short-chain fatty acid metabolic process", "id": "GO:0046459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046459", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "rDNA heterochromatin formation", "id": "GO:0000183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000183", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "mRNA transcription", "id": "GO:0009299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009299", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "replication-born double-strand break repair via sister chromatid exchange", "id": "GO:1990414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990414", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "DNA repair-dependent chromatin remodeling", "id": "GO:0140861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140861", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "mating-type region heterochromatin", "id": "GO:0031934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031934", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "NAD+ binding", "id": "GO:0070403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070403", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" }, { "name": "histone deacetylase activity, NAD-dependent", "id": "GO:0017136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017136", "evidence": [ { "database": "UniProtKB", "id": "P53688", "url": "https://www.uniprot.org/uniprotkb/P53688" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53688-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Thr10", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 10, "start_aa": "Thr", "end_pos": 10, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr10", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] } ], "record_id": "P53688-1" }, { "uniprot_canonical_ac": "P53833-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 195, "chemical_mass": 22612.0, "gene_names": "POP3;N0586;POP3", "protein_name": "Ribonucleases P/MRP protein subunit POP3", "disease": [], "cellular_component": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, RNase MRP-dependent", "id": "GO:0000294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000294", "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "pmid": "" }, { "name": "intronic box C/D snoRNA processing", "id": "GO:0034965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034965", "evidence": [ { "database": "UniProtKB", "id": "P53833", "url": "https://www.uniprot.org/uniprotkb/P53833" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P53833-1" }, { "uniprot_canonical_ac": "P53844-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 350, "chemical_mass": 40678.0, "gene_names": "PDR17;ISS1;N0815;PDR17;PSTB2;SFH4", "protein_name": "Phosphatidylinositol transfer protein PDR17", "disease": [ { "disease_id": "DOID:0050683", "name": "Bothnia retinal dystrophy", "description": "A fundus dystrophy that is characterized by early onset of night blindness and decreased visual acuity that progresses to blindness in early adulthood, has_material_basis_in mutation in RLBP1 gene.", "url": "https://disease-ontology.org/term/DOID:0050683", "evidence": [ { "id": "0050683", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050683" } ], "weight": 0.0 }, { "disease_id": "DOID:0111015", "name": "Newfoundland cone-rod dystrophy", "description": "A cone-rod dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the RLBP1 gene on chromosome 15q26.", "url": "https://disease-ontology.org/term/DOID:0111015", "evidence": [ { "id": "0111015", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111015" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:11105", "name": "fundus albipunctatus", "description": "A fundus dystrophy that is characterized by discrete uniform white dots over the entire fundus with greatest density in the midperiphery and no macular involvement.", "url": "https://disease-ontology.org/term/DOID:11105", "evidence": [ { "id": "11105", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11105" } ], "weight": 0.0 }, { "disease_id": "DOID:8499", "name": "night blindness", "description": "A retinal disease that is characterized by difficulty or the inability to see in relatively low light.", "url": "https://disease-ontology.org/term/DOID:8499", "evidence": [ { "id": "8499", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8499" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" } ], "biological_process": [ { "name": "sterol biosynthetic process", "id": "GO:0016126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016126", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylcholine biosynthetic process", "id": "GO:2001247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001247", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "phosphatidylserine metabolic process", "id": "GO:0006658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006658", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "intermembrane phospholipid transfer", "id": "GO:0120010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120010", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylglycerol biosynthetic process", "id": "GO:1901352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901352", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" } ], "molecular_function": [ { "name": "sterol binding", "id": "GO:0032934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032934", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" }, { "name": "phosphatidylinositol transfer activity", "id": "GO:0008526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008526", "evidence": [ { "database": "UniProtKB", "id": "P53844", "url": "https://www.uniprot.org/uniprotkb/P53844" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53844-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Thr11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005208", "url": "https://www.yeastgenome.org/locus/S000005208" }, { "database": "iPTMnet", "id": "P53844", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53844" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53844-1" }, { "uniprot_canonical_ac": "P53855-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1592, "chemical_mass": 178414.0, "gene_names": "ATG2;APG2;ATG2;AUT8;N1106;SPO72", "protein_name": "Autophagy-related protein 2", "disease": [], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "glycophagy", "id": "GO:0061723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061723", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "extrinsic component of phagophore assembly site membrane", "id": "GO:0097632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097632", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "phagophore", "id": "GO:0061908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061908", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" }, { "name": "lipid transfer activity", "id": "GO:0120013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120013", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53855-1", "start_pos": "1013", "end_pos": "1013", "site_lbl": "Thr1013", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005186", "url": "https://www.yeastgenome.org/locus/S000005186" }, { "database": "iPTMnet", "id": "P53855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53855" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53855-1", "start_pos": "1056", "end_pos": "1056", "site_lbl": "Thr1056", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005186", "url": "https://www.yeastgenome.org/locus/S000005186" }, { "database": "iPTMnet", "id": "P53855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53855" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53855-1", "start_pos": "1086", "end_pos": "1086", "site_lbl": "Ser1086", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" }, { "database": "iPTMnet", "id": "P53855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53855" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Does not affect autophagy; when associated with A-249.", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Phospho-mimetic mutant; does not affect autophagy; when associated with D-249.", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] } ] }, { "uniprot_canonical_ac": "P53855-1", "start_pos": "1113", "end_pos": "1113", "site_lbl": "Ser1113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53855" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005186", "url": "https://www.yeastgenome.org/locus/S000005186" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53855-1", "start_pos": "1154", "end_pos": "1154", "site_lbl": "Ser1154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005186", "url": "https://www.yeastgenome.org/locus/S000005186" }, { "database": "iPTMnet", "id": "P53855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53855" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53855-1", "start_pos": "1351", "end_pos": "1351", "site_lbl": "Ser1351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005186", "url": "https://www.yeastgenome.org/locus/S000005186" }, { "database": "iPTMnet", "id": "P53855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53855" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53855-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Ser140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005186", "url": "https://www.yeastgenome.org/locus/S000005186" }, { "database": "iPTMnet", "id": "P53855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53855" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53855-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Ser236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53855" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005186", "url": "https://www.yeastgenome.org/locus/S000005186" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53855-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Ser249", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" }, { "database": "SGD", "id": "S000005186", "url": "https://www.yeastgenome.org/locus/S000005186" }, { "database": "iPTMnet", "id": "P53855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53855" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Does not affect autophagy; when associated with A-1086.", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Phospho-mimetic mutant; does not affect autophagy; when associated with D-1086.", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] } ] }, { "uniprot_canonical_ac": "P53855-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005186", "url": "https://www.yeastgenome.org/locus/S000005186" }, { "database": "iPTMnet", "id": "P53855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53855" }, { "database": "PubMed", "id": "31553916", "url": "https://glygen.org/publication/PubMed/31553916" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53855-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Gly83", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "Leads to a severely reduced activity of autophagy and a dispersed localization in the cytoplasm.", "evidence": [ { "database": "UniProtKB", "id": "P53855", "url": "https://www.uniprot.org/uniprotkb/P53855" }, { "database": "PubMed", "id": "11382761", "url": "https://glygen.org/publication/PubMed/11382761" } ] } ] } ], "record_id": "P53855-1" }, { "uniprot_canonical_ac": "P53863-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 590, "chemical_mass": 68783.0, "gene_names": "JJJ1;JJJ1;N1254", "protein_name": "J protein JJJ1", "disease": [], "biological_process": [ { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" }, { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" }, { "name": "regulation of cell size", "id": "GO:0008361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008361", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53863-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005171", "url": "https://www.yeastgenome.org/locus/S000005171" }, { "database": "iPTMnet", "id": "P53863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53863" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53863-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53863" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005171", "url": "https://www.yeastgenome.org/locus/S000005171" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53863-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Ser397", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53863" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005171", "url": "https://www.yeastgenome.org/locus/S000005171" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53863-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Thr471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53863" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005171", "url": "https://www.yeastgenome.org/locus/S000005171" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53863-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Thr473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53863" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P53863-1", "start_pos": "476", "end_pos": "476", "site_lbl": "Ser476", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53863" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005171", "url": "https://www.yeastgenome.org/locus/S000005171" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53863-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Ser487", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53863" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005171", "url": "https://www.yeastgenome.org/locus/S000005171" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53863-1", "start_pos": "496", "end_pos": "496", "site_lbl": "Ser496", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005171", "url": "https://www.yeastgenome.org/locus/S000005171" }, { "database": "iPTMnet", "id": "P53863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53863" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53863-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Thr504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53863", "url": "https://www.uniprot.org/uniprotkb/P53863" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53863" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005171", "url": "https://www.yeastgenome.org/locus/S000005171" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53863-1" }, { "uniprot_canonical_ac": "P53867-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 494, "chemical_mass": 55143.0, "gene_names": "ATG4;APG4;ATG4;AUT2;N1274", "protein_name": "Cysteine protease ATG4", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "C-terminal protein lipidation", "id": "GO:0006501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006501", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "protein delipidation", "id": "GO:0051697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051697", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "aggrephagy", "id": "GO:0035973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035973", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" }, { "name": "protein-phosphatidylethanolamide deconjugating activity", "id": "GO:0019786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019786", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53867-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005167", "url": "https://www.yeastgenome.org/locus/S000005167" }, { "database": "iPTMnet", "id": "P53867", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53867" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53867", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53867" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" }, { "database": "iPTMnet", "id": "P53867", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53867" }, { "database": "PubMed", "id": "28821724", "url": "https://glygen.org/publication/PubMed/28821724" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolished phosphorylation by ATG1, leading to increased interaction with ATG8.", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" }, { "database": "PubMed", "id": "28821724", "url": "https://glygen.org/publication/PubMed/28821724" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Phospho-mimetic mutant; decreased integration with ATG8, leading to impaired decreased delipdation of ATG8.", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" }, { "database": "PubMed", "id": "28821724", "url": "https://glygen.org/publication/PubMed/28821724" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005167", "url": "https://www.yeastgenome.org/locus/S000005167" }, { "database": "iPTMnet", "id": "P53867", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53867" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Tyr43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53867", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53867" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Thr483", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005167", "url": "https://www.yeastgenome.org/locus/S000005167" }, { "database": "iPTMnet", "id": "P53867", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53867" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Ser488", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53867", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53867" }, { "database": "SGD", "id": "S000005167", "url": "https://www.yeastgenome.org/locus/S000005167" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005167", "url": "https://www.yeastgenome.org/locus/S000005167" }, { "database": "iPTMnet", "id": "P53867", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53867" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Thr83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005167", "url": "https://www.yeastgenome.org/locus/S000005167" }, { "database": "iPTMnet", "id": "P53867", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53867" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Cys147", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Abolishes the proteolytic activity and decreases autophagy.", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" }, { "database": "PubMed", "id": "11038174", "url": "https://glygen.org/publication/PubMed/11038174" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes the proteolytic activity and decreases autophagy.", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" }, { "database": "PubMed", "id": "11038174", "url": "https://glygen.org/publication/PubMed/11038174" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Cys338", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Increased recruitmentto the phagophore assembly site.", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" }, { "database": "PubMed", "id": "25483965", "url": "https://glygen.org/publication/PubMed/25483965" } ] } ] }, { "uniprot_canonical_ac": "P53867-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Cys394", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Increased recruitmentto the phagophore assembly site.", "evidence": [ { "database": "UniProtKB", "id": "P53867", "url": "https://www.uniprot.org/uniprotkb/P53867" }, { "database": "PubMed", "id": "25483965", "url": "https://glygen.org/publication/PubMed/25483965" } ] } ] } ], "record_id": "P53867-1" }, { "uniprot_canonical_ac": "P53877-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 555, "chemical_mass": 61773.0, "gene_names": "IPI3;IPI3;N1636", "protein_name": "Pre-rRNA-processing protein IPI3", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nuclear pre-replicative complex", "id": "GO:0005656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005656", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "pmid": "" }, { "name": "rixosome complex", "id": "GO:0120330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120330", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "pmid": "" } ], "biological_process": [ { "name": "pre-replicative complex assembly involved in nuclear cell cycle DNA replication", "id": "GO:0006267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006267", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "pmid": "" }, { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53877-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005126", "url": "https://www.yeastgenome.org/locus/S000005126" }, { "database": "iPTMnet", "id": "P53877", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53877" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53877-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53877", "url": "https://www.uniprot.org/uniprotkb/P53877" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53877", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53877" }, { "database": "SGD", "id": "S000005126", "url": "https://www.yeastgenome.org/locus/S000005126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53877-1", "start_pos": "391", "end_pos": "391", "site_lbl": "Ser391", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005126", "url": "https://www.yeastgenome.org/locus/S000005126" }, { "database": "iPTMnet", "id": "P53877", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53877" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53877-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Thr507", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005126", "url": "https://www.yeastgenome.org/locus/S000005126" }, { "database": "iPTMnet", "id": "P53877", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53877" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53877-1", "start_pos": "508", "end_pos": "508", "site_lbl": "Ser508", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005126", "url": "https://www.yeastgenome.org/locus/S000005126" }, { "database": "iPTMnet", "id": "P53877", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53877" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53877-1", "start_pos": "509", "end_pos": "509", "site_lbl": "Ser509", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005126", "url": "https://www.yeastgenome.org/locus/S000005126" }, { "database": "iPTMnet", "id": "P53877", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53877" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53877-1", "start_pos": "512", "end_pos": "512", "site_lbl": "Ser512", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005126", "url": "https://www.yeastgenome.org/locus/S000005126" }, { "database": "iPTMnet", "id": "P53877", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53877" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53877-1" }, { "uniprot_canonical_ac": "P53886-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1748, "chemical_mass": 196162.0, "gene_names": "APC1;APC1;N1677", "protein_name": "Anaphase-promoting complex subunit 1", "disease": [ { "disease_id": "DOID:2732", "name": "Rothmund-Thomson syndrome", "description": "A skin disease characterized by poikiloderma, congenital bone defects, and an increased risk of osteosarcoma in childhood and skin cancer later in life that has_material_basis_in homozygous or compound heterozygous mutation in the DNA helicase gene RECQL4 on chromosome 8q24.", "url": "https://disease-ontology.org/term/DOID:2732", "evidence": [ { "id": "2732", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2732" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "exit from mitosis", "id": "GO:0010458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010458", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "regulation of meiotic cell cycle", "id": "GO:0051445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051445", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53886-1", "start_pos": "1436", "end_pos": "1436", "site_lbl": "Ser1436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "1439", "end_pos": "1439", "site_lbl": "Thr1439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "1442", "end_pos": "1442", "site_lbl": "Thr1442", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "1443", "end_pos": "1443", "site_lbl": "Ser1443", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "1445", "end_pos": "1445", "site_lbl": "Thr1445", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "1447", "end_pos": "1447", "site_lbl": "Thr1447", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "1451", "end_pos": "1451", "site_lbl": "Ser1451", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "1459", "end_pos": "1459", "site_lbl": "Thr1459", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "1462", "end_pos": "1462", "site_lbl": "Ser1462", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53886", "url": "https://www.uniprot.org/uniprotkb/P53886" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "1468", "end_pos": "1468", "site_lbl": "Ser1468", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "1665", "end_pos": "1665", "site_lbl": "Ser1665", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Ser247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Ser272", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Ser308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Ser310", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Ser392", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "870", "end_pos": "870", "site_lbl": "Ser870", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "872", "end_pos": "872", "site_lbl": "Ser872", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53886-1", "start_pos": "884", "end_pos": "884", "site_lbl": "Ser884", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005116", "url": "https://www.yeastgenome.org/locus/S000005116" }, { "database": "iPTMnet", "id": "P53886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53886-1" }, { "uniprot_canonical_ac": "P53900-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53900", "url": "https://www.uniprot.org/uniprotkb/P53900" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 129, "chemical_mass": 15180.0, "gene_names": "GIM3;GIM3;N1761;PFD4", "protein_name": "Prefoldin subunit 4", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53900", "url": "https://www.uniprot.org/uniprotkb/P53900" } ], "pmid": "" }, { "name": "prefoldin complex", "id": "GO:0016272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016272", "evidence": [ { "database": "UniProtKB", "id": "P53900", "url": "https://www.uniprot.org/uniprotkb/P53900" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P53900", "url": "https://www.uniprot.org/uniprotkb/P53900" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "P53900", "url": "https://www.uniprot.org/uniprotkb/P53900" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P53900", "url": "https://www.uniprot.org/uniprotkb/P53900" } ], "pmid": "" }, { "name": "tubulin complex assembly", "id": "GO:0007021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007021", "evidence": [ { "database": "UniProtKB", "id": "P53900", "url": "https://www.uniprot.org/uniprotkb/P53900" } ], "pmid": "" }, { "name": "cytoplasm protein quality control by the ubiquitin-proteasome system", "id": "GO:0071629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071629", "evidence": [ { "database": "UniProtKB", "id": "P53900", "url": "https://www.uniprot.org/uniprotkb/P53900" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P53900", "url": "https://www.uniprot.org/uniprotkb/P53900" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53900-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Thr12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005097", "url": "https://www.yeastgenome.org/locus/S000005097" }, { "database": "iPTMnet", "id": "P53900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53900" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P53900-1" }, { "uniprot_canonical_ac": "P53901-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 409, "chemical_mass": 46226.0, "gene_names": "INN1;INN1;N1765", "protein_name": "Ingression protein 1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" }, { "name": "HICS complex", "id": "GO:0044697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044697", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" }, { "name": "cellular bud neck contractile ring", "id": "GO:0000142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000142", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" }, { "name": "mitotic cytokinetic process", "id": "GO:1902410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902410", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" }, { "name": "secondary cell septum biogenesis", "id": "GO:1990344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990344", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53901-1", "start_pos": "386", "end_pos": "386", "site_lbl": "Ser386", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 386, "start_aa": "Ser", "end_pos": 386, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser386", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53901", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53901" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 388, "start_aa": "Ser", "end_pos": 388, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser388", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53901", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53901" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Ser392", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 392, "start_aa": "Ser", "end_pos": 392, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser392", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53901", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53901" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Ser154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Ser208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Ser275", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Ser341", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Ser363", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Ser364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Ser376", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Ser398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005096", "url": "https://www.yeastgenome.org/locus/S000005096" }, { "database": "iPTMnet", "id": "P53901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53901" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Lys28", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Impairs plasma membrane ingression; when associated with A-31.", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" }, { "database": "PubMed", "id": "18344988", "url": "https://glygen.org/publication/PubMed/18344988" } ] } ] }, { "uniprot_canonical_ac": "P53901-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Lys31", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Impairs plasma membrane ingression; when associated with A-28.", "evidence": [ { "database": "UniProtKB", "id": "P53901", "url": "https://www.uniprot.org/uniprotkb/P53901" }, { "database": "PubMed", "id": "18344988", "url": "https://glygen.org/publication/PubMed/18344988" } ] } ] } ], "record_id": "P53901-1" }, { "uniprot_canonical_ac": "P53909-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 347, "chemical_mass": 39635.0, "gene_names": "AAH1;AAH1;N1208;N1825", "protein_name": "Adenine deaminase", "disease": [ { "disease_id": "DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue.", "url": "https://disease-ontology.org/term/DOID:0050865", "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:10113", "name": "trypanosomiasis", "description": "A parasitic protozoa infectious disease that involves infection caused by parasitic protozoan of the genus Trypanosoma in animals and humans.", "url": "https://disease-ontology.org/term/DOID:10113", "evidence": [ { "id": "10113", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10113" } ], "weight": 0.0 }, { "disease_id": "DOID:10457", "name": "Legionnaires' disease", "description": "A legionellosis that is characterized by severe form of infection producing pneumonia. Symptoms include fever, chills, and cough.", "url": "https://disease-ontology.org/term/DOID:10457", "evidence": [ { "id": "10457", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10457" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:106", "name": "pleural tuberculosis", "description": "An extrapulmonary tuberculosis that results_in lymphocyte-predominant exudative pleural effusion, located_in pleura. This results from an allergic response to tuberculoprotein causing the permeabiltity of the pleural vasculature to alter leading to a sub-pleural caseous focus rupture into the pleural sac.", "url": "https://disease-ontology.org/term/DOID:106", "evidence": [ { "id": "106", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:106" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10808", "name": "gastric ulcer", "description": "", "url": "https://disease-ontology.org/term/DOID:10808", "evidence": [ { "id": "10808", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10808" } ], "weight": 0.0 }, { "disease_id": "DOID:11100", "name": "Q fever", "description": "A primary bacterial infectious disease that is a zoonotic infectious disease affecting multiple organs, has_material_basis_in Coxiella burnetii, which is transmitted_by inhalation of air contaminated by barnyard dust containing dried placental material, birth fluids, or excreta of infected herd animals, transmitted_by ingestion of contaminated milk, transmitted_by tick bites and transmitted_by contact with infected person. The infection has_symptom fever, has_symptom headache, has_symptom cough, has_symptom pleuritic chest pain, has_symptom myalgia and has_symptom arthralgia.", "url": "https://disease-ontology.org/term/DOID:11100", "evidence": [ { "id": "11100", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11100" } ], "weight": 0.0 }, { "disease_id": "DOID:11396", "name": "pulmonary edema", "description": "A respiratory failure that is characterized by the accumulation of fluid in the lung tissues causing disturbance of the gas exchange that may lead to respiratory failure.", "url": "https://disease-ontology.org/term/DOID:11396", "evidence": [ { "id": "11396", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11396" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:13223", "name": "uterine fibroid", "description": "An uterine benign neoplasm derived from the smooth muscle layer of the uterus.", "url": "https://disease-ontology.org/term/DOID:13223", "evidence": [ { "id": "13223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13223" } ], "weight": 0.0 }, { "disease_id": "DOID:13276", "name": "Mycoplasma pneumoniae pneumonia", "description": "A bacterial pneumonia that is caused by the bacterial species Mycoplasma pneumoniae. The symptoms include chest pain, chills, dry cough which is not bloody, excessive sweating, fever, headache and sore throat.", "url": "https://disease-ontology.org/term/DOID:13276", "evidence": [ { "id": "13276", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13276" } ], "weight": 0.0 }, { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:14484", "name": "sporotrichosis", "description": "A primary systemic mycosis that results_in a systemic fungal infection, has_material_basis_in Sporothrix schenckii in animals and humans and results_in_formation_of red papule at the site of inoculation.", "url": "https://disease-ontology.org/term/DOID:14484", "evidence": [ { "id": "14484", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14484" } ], "weight": 0.0 }, { "disease_id": "DOID:1790", "name": "malignant mesothelioma", "description": "A cell type cancer that has_material_basis_in mesothelial tissue that develops from the thin layer of tissue that covers many of the internal organs. Exposure to airborne asbestos particles increases one's risk of developing malignant mesothelioma.", "url": "https://disease-ontology.org/term/DOID:1790", "evidence": [ { "id": "1790", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1790" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:2297", "name": "leptospirosis", "description": "A primary bacterial infectious disease that involves systemic infection, has_material_basis_in Leptospira, which is transmitted by contact with water, food, or soil containing urine from the infected animals. The infection has symptom jaundice, has symptom chills, has symptom fever, has symptom muscle pain, and has symptom hepatomegaly.", "url": "https://disease-ontology.org/term/DOID:2297", "evidence": [ { "id": "2297", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2297" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2876", "name": "laryngeal squamous cell carcinoma", "description": "A laryngeal carcinoma that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:2876", "evidence": [ { "id": "2876", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2876" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:5810", "name": "adenosine deaminase deficiency", "description": "A severe combined immunodeficiency that is caused by a defective enzyme, adenosine deaminase (ADA), necessary for the breakdown of purines. Lack of ADA causes accumulation of dATP.", "url": "https://disease-ontology.org/term/DOID:5810", "evidence": [ { "id": "5810", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5810" } ], "weight": 0.0 }, { "disease_id": "DOID:627", "name": "severe combined immunodeficiency", "description": "A combined T cell and B cell immunodeficiency that is caused by a defect in infection-fighting immune cells resulting in individuals with non-functional immune systems.", "url": "https://disease-ontology.org/term/DOID:627", "evidence": [ { "id": "627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:627" } ], "weight": 0.0 }, { "disease_id": "DOID:8283", "name": "peritonitis", "description": "A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.", "url": "https://disease-ontology.org/term/DOID:8283", "evidence": [ { "id": "8283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8283" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 }, { "disease_id": "DOID:8618", "name": "oral cavity cancer", "description": "A gastrointestinal system cancer that is located_in the oral cavity.", "url": "https://disease-ontology.org/term/DOID:8618", "evidence": [ { "id": "8618", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8618" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" } ], "pmid": "" }, { "name": "adenine deaminase activity", "id": "GO:0000034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000034", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" } ], "pmid": "" }, { "name": "purine-containing compound salvage", "id": "GO:0043101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043101", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" } ], "pmid": "" }, { "name": "purine ribonucleoside monophosphate biosynthetic process", "id": "GO:0009168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009168", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" } ], "pmid": "" }, { "name": "hypoxanthine salvage", "id": "GO:0043103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043103", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" } ], "pmid": "" }, { "name": "adenine catabolic process", "id": "GO:0006146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006146", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53909-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Ser264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005085", "url": "https://www.yeastgenome.org/locus/S000005085" }, { "database": "iPTMnet", "id": "P53909", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53909" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53909-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005085", "url": "https://www.yeastgenome.org/locus/S000005085" }, { "database": "iPTMnet", "id": "P53909", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53909" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53909-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005085", "url": "https://www.yeastgenome.org/locus/S000005085" }, { "database": "iPTMnet", "id": "P53909", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53909" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53909-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Asp219", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "G", "comment": "In aah1-4; impairs AAH1 degradation during postdiauxic growth and leads to weak interaction with SAF1.", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" }, { "database": "PubMed", "id": "17517885", "url": "https://glygen.org/publication/PubMed/17517885" } ] } ] }, { "uniprot_canonical_ac": "P53909-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Glu237", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "V", "comment": "In aah1-6; impairs AAH1 degradation during postdiauxic growth and leads to weak interaction with SAF1.", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" }, { "database": "PubMed", "id": "17517885", "url": "https://glygen.org/publication/PubMed/17517885" } ] } ] }, { "uniprot_canonical_ac": "P53909-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Lys329", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "In aah1-7; impairs AAH1 degradation during postdiauxic growth.", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" }, { "database": "PubMed", "id": "17517885", "url": "https://glygen.org/publication/PubMed/17517885" } ] } ] }, { "uniprot_canonical_ac": "P53909-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ile69", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "T", "comment": "In aah1-2; impairs AAH1 degradation during postdiauxic growth and leads to weak interaction with SAF1.", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" }, { "database": "PubMed", "id": "17517885", "url": "https://glygen.org/publication/PubMed/17517885" } ] } ] }, { "uniprot_canonical_ac": "P53909-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Asn72", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "K", "comment": "In aah1-3; impairs AAH1 degradation during postdiauxic growth and leads to weak interaction with SAF1.", "evidence": [ { "database": "UniProtKB", "id": "P53909", "url": "https://www.uniprot.org/uniprotkb/P53909" }, { "database": "PubMed", "id": "17517885", "url": "https://glygen.org/publication/PubMed/17517885" } ] } ] } ], "record_id": "P53909-1" }, { "uniprot_canonical_ac": "P53923-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 493, "chemical_mass": 56473.0, "gene_names": "NCS2;CTU2;N1913;NCS2;TUC2", "protein_name": "Cytoplasmic tRNA 2-thiolation protein 2", "disease": [], "biological_process": [ { "name": "tRNA wobble position uridine thiolation", "id": "GO:0002143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002143", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" }, { "name": "tRNA thio-modification", "id": "GO:0034227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034227", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" }, { "name": "protein urmylation", "id": "GO:0032447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032447", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" }, { "name": "invasive growth in response to glucose limitation", "id": "GO:0001403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001403", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" }, { "name": "pseudohyphal growth", "id": "GO:0007124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007124", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" } ], "molecular_function": [ { "name": "sulfurtransferase activity", "id": "GO:0016783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016783", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53923-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53923", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53923" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005063", "url": "https://www.yeastgenome.org/locus/S000005063" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53923-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53923", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53923" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005063", "url": "https://www.yeastgenome.org/locus/S000005063" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53923-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Ser312", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005063", "url": "https://www.yeastgenome.org/locus/S000005063" }, { "database": "iPTMnet", "id": "P53923", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53923" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53923-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Thr387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005063", "url": "https://www.yeastgenome.org/locus/S000005063" }, { "database": "iPTMnet", "id": "P53923", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53923" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53923-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005063", "url": "https://www.yeastgenome.org/locus/S000005063" }, { "database": "iPTMnet", "id": "P53923", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53923" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53923-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Tyr390", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005063", "url": "https://www.yeastgenome.org/locus/S000005063" }, { "database": "iPTMnet", "id": "P53923", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53923" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53923-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Ser489", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53923", "url": "https://www.uniprot.org/uniprotkb/P53923" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P53923", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53923" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005063", "url": "https://www.yeastgenome.org/locus/S000005063" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53923-1" }, { "uniprot_canonical_ac": "P53927-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 220, "chemical_mass": 25447.0, "gene_names": "NOP15;N1954;NOP15", "protein_name": "Ribosome biogenesis protein 15", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "pmid": "" }, { "name": "ribosomal large subunit binding", "id": "GO:0043023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043023", "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "P53927", "url": "https://www.uniprot.org/uniprotkb/P53927" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53927-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53927" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005054", "url": "https://www.yeastgenome.org/locus/S000005054" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53927-1" }, { "uniprot_canonical_ac": "P53951-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53951", "url": "https://www.uniprot.org/uniprotkb/P53951" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 403, "chemical_mass": 45604.0, "gene_names": "COG5;API4;COD4;COG5;N2476;YNL2476W", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "disease": [ { "disease_id": "DOID:0070261", "name": "congenital disorder of glycosylation type IIi", "description": "A congenital disorder of glycosylation type II that has_material_basis_in a mutation of the COG5 gene on chromosome 7q22.3.", "url": "https://disease-ontology.org/term/DOID:0070261", "evidence": [ { "id": "0070261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070261" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P53951", "url": "https://www.uniprot.org/uniprotkb/P53951" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P53951", "url": "https://www.uniprot.org/uniprotkb/P53951" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "P53951", "url": "https://www.uniprot.org/uniprotkb/P53951" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P53951", "url": "https://www.uniprot.org/uniprotkb/P53951" } ], "pmid": "" } ], "biological_process": [ { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "P53951", "url": "https://www.uniprot.org/uniprotkb/P53951" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P53951", "url": "https://www.uniprot.org/uniprotkb/P53951" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P53951", "url": "https://www.uniprot.org/uniprotkb/P53951" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53951-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004996", "url": "https://www.yeastgenome.org/locus/S000004996" }, { "database": "iPTMnet", "id": "P53951", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53951" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53951-1" }, { "uniprot_canonical_ac": "P53955-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 656, "chemical_mass": 74785.0, "gene_names": "SLM2;LIT1;N2515;SLM2;YNL2515P", "protein_name": "Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" } ], "biological_process": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" }, { "name": "TOR signaling", "id": "GO:0031929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031929", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" }, { "name": "establishment or maintenance of actin cytoskeleton polarity", "id": "GO:0030950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030950", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" }, { "name": "eisosome assembly", "id": "GO:0070941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070941", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53955-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 11, "start_aa": "Ser", "end_pos": 11, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser11", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53955", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53955" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 7, "start_aa": "Ser", "end_pos": 7, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser7", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P53955", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P53955" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Thr266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Ser523", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Ser586", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "588", "end_pos": "588", "site_lbl": "Thr588", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "592", "end_pos": "592", "site_lbl": "Thr592", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "597", "end_pos": "597", "site_lbl": "Thr597", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "603", "end_pos": "603", "site_lbl": "Ser603", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Ser604", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "605", "end_pos": "605", "site_lbl": "Ser605", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "611", "end_pos": "611", "site_lbl": "Ser611", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "619", "end_pos": "619", "site_lbl": "Thr619", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Thr621", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "623", "end_pos": "623", "site_lbl": "Thr623", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "624", "end_pos": "624", "site_lbl": "Thr624", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "625", "end_pos": "625", "site_lbl": "Ser625", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Ser626", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "649", "end_pos": "649", "site_lbl": "Ser649", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53955-1", "start_pos": "653", "end_pos": "653", "site_lbl": "Ser653", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P53955", "url": "https://www.uniprot.org/uniprotkb/P53955" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P53955", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53955" }, { "database": "SGD", "id": "S000004992", "url": "https://www.yeastgenome.org/locus/S000004992" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P53955-1" }, { "uniprot_canonical_ac": "P53959-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53959", "url": "https://www.uniprot.org/uniprotkb/P53959" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 839, "chemical_mass": 96976.0, "gene_names": "COG6;COD2;COG6;N2675;SEC37;TFI2", "protein_name": "Conserved oligomeric Golgi complex subunit 6", "disease": [ { "disease_id": "DOID:0070264", "name": "congenital disorder of glycosylation type IIl", "description": "A congenital disorder of glycosylation type II that has_material_basis_in an autosomal recessive mutation of the COG6 gene on chromosome 13q14.11.", "url": "https://disease-ontology.org/term/DOID:0070264", "evidence": [ { "id": "0070264", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070264" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P53959", "url": "https://www.uniprot.org/uniprotkb/P53959" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "P53959", "url": "https://www.uniprot.org/uniprotkb/P53959" } ], "pmid": "" } ], "biological_process": [ { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "P53959", "url": "https://www.uniprot.org/uniprotkb/P53959" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P53959", "url": "https://www.uniprot.org/uniprotkb/P53959" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P53959", "url": "https://www.uniprot.org/uniprotkb/P53959" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P53959-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Ser100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004986", "url": "https://www.yeastgenome.org/locus/S000004986" }, { "database": "iPTMnet", "id": "P53959", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53959" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53959-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Ser128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004986", "url": "https://www.yeastgenome.org/locus/S000004986" }, { "database": "iPTMnet", "id": "P53959", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53959" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53959-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004986", "url": "https://www.yeastgenome.org/locus/S000004986" }, { "database": "iPTMnet", "id": "P53959", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53959" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P53959-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Thr343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004986", "url": "https://www.yeastgenome.org/locus/S000004986" }, { "database": "iPTMnet", "id": "P53959", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53959" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P53959-1" }, { "uniprot_canonical_ac": "P54005-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P54005", "url": "https://www.uniprot.org/uniprotkb/P54005" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 336, "chemical_mass": 38760.0, "gene_names": "DIA1;DIA1;YM9924.08", "protein_name": "Protein DIA1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P54005", "url": "https://www.uniprot.org/uniprotkb/P54005" } ], "pmid": "" } ], "biological_process": [ { "name": "invasive growth in response to glucose limitation", "id": "GO:0001403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001403", "evidence": [ { "database": "UniProtKB", "id": "P54005", "url": "https://www.uniprot.org/uniprotkb/P54005" } ], "pmid": "" }, { "name": "pseudohyphal growth", "id": "GO:0007124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007124", "evidence": [ { "database": "UniProtKB", "id": "P54005", "url": "https://www.uniprot.org/uniprotkb/P54005" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P54005-1" }, { "uniprot_canonical_ac": "P54791-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 529, "chemical_mass": 60705.0, "gene_names": "ORC4;ORC4;P9325.5", "protein_name": "Origin recognition complex subunit 4", "disease": [ { "disease_id": "DOID:0060306", "name": "Meier-Gorlin syndrome", "description": "A syndrome that is characterized by bilateral underdevelopment of the external ear, short stature, absent or underdeveloped patellae and severe prenatal and postnatal growth retardation.", "url": "https://disease-ontology.org/term/DOID:0060306", "evidence": [ { "id": "0060306", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060306" } ], "weight": 0.0 }, { "disease_id": "DOID:0080513", "name": "Meier-Gorlin syndrome 2", "description": "A Meier-Gorlin syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the ORC4 gene on chromosome 2q23.", "url": "https://disease-ontology.org/term/DOID:0080513", "evidence": [ { "id": "0080513", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080513" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pre-replicative complex", "id": "GO:0005656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005656", "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" } ], "pmid": "" }, { "name": "DNA replication preinitiation complex", "id": "GO:0031261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031261", "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" } ], "pmid": "" }, { "name": "nuclear origin of replication recognition complex", "id": "GO:0005664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005664", "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" } ], "pmid": "" } ], "biological_process": [ { "name": "pre-replicative complex assembly involved in nuclear cell cycle DNA replication", "id": "GO:0006267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006267", "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" } ], "pmid": "" }, { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P54791-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006366", "url": "https://www.yeastgenome.org/locus/S000006366" }, { "database": "iPTMnet", "id": "P54791", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P54791" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P54791-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Thr293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P54791", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P54791" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P54791-1", "start_pos": "440", "end_pos": "440", "site_lbl": "Ser440", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006366", "url": "https://www.yeastgenome.org/locus/S000006366" }, { "database": "iPTMnet", "id": "P54791", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P54791" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P54791-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006366", "url": "https://www.yeastgenome.org/locus/S000006366" }, { "database": "iPTMnet", "id": "P54791", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P54791" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P54791-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P54791", "url": "https://www.uniprot.org/uniprotkb/P54791" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P54791", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P54791" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006366", "url": "https://www.yeastgenome.org/locus/S000006366" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P54791-1" }, { "uniprot_canonical_ac": "P57743-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 89, "chemical_mass": 10030.0, "gene_names": "LSM3;LSM3;SMX4;USS2", "protein_name": "LSM complex subunit LSM3", "disease": [], "biological_process": [ { "name": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0000290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000290", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "P-body assembly", "id": "GO:0033962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "sno(s)RNA-containing ribonucleoprotein complex", "id": "GO:0005732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005732", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "U6 snRNP", "id": "GO:0005688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005688", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" }, { "name": "Lsm1-7-Pat1 complex", "id": "GO:1990726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990726", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P57743-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006434", "url": "https://www.yeastgenome.org/locus/S000006434" }, { "database": "iPTMnet", "id": "P57743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P57743" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P57743-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Arg21", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Sensitive to thermal stress. Decreases binding affinity for U6 snRNA.", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" }, { "database": "PubMed", "id": "29717126", "url": "https://glygen.org/publication/PubMed/29717126" } ] } ] }, { "uniprot_canonical_ac": "P57743-1", "start_pos": "36", "end_pos": "36", "site_lbl": "His36", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Strongly reduces affinity for poly-URNA ends.", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" }, { "database": "PubMed", "id": "24240276", "url": "https://glygen.org/publication/PubMed/24240276" } ] } ] }, { "uniprot_canonical_ac": "P57743-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Asn38", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Strongly reduces affinity for poly-URNA ends.", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" }, { "database": "PubMed", "id": "24240276", "url": "https://glygen.org/publication/PubMed/24240276" } ] } ] }, { "uniprot_canonical_ac": "P57743-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Arg69", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Strongly reduces affinity for poly-URNA ends.", "evidence": [ { "database": "UniProtKB", "id": "P57743", "url": "https://www.uniprot.org/uniprotkb/P57743" }, { "database": "PubMed", "id": "24240276", "url": "https://glygen.org/publication/PubMed/24240276" }, { "database": "PubMed", "id": "24513854", "url": "https://glygen.org/publication/PubMed/24513854" } ] } ] } ], "record_id": "P57743-1" }, { "uniprot_canonical_ac": "P57744-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P57744", "url": "https://www.uniprot.org/uniprotkb/P57744" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 87, "chemical_mass": 9764.0, "gene_names": "TIM8;TIM8;YJR135BW", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM8", "disease": [ { "disease_id": "DOID:0050757", "name": "deafness-dystonia-optic neuronopathy syndrome", "description": "A mitochondrial metabolism disease that is characterized by hearing loss that begins early in life, problems with movement, impaired vision, and behavior problems, and has_material_basis_in mutations in the TIMM8A gene resulting in abnormal protein transport within the mitochondria.", "url": "https://disease-ontology.org/term/DOID:0050757", "evidence": [ { "id": "0050757", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050757" } ], "weight": 0.0 }, { "disease_id": "DOID:543", "name": "dystonia", "description": "A movement disease that is characterized by involuntary muscle contractions causing repetitive or twisting movements.", "url": "https://disease-ontology.org/term/DOID:543", "evidence": [ { "id": "543", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:543" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial intermembrane space chaperone complex", "id": "GO:0042719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042719", "evidence": [ { "database": "UniProtKB", "id": "P57744", "url": "https://www.uniprot.org/uniprotkb/P57744" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P57744", "url": "https://www.uniprot.org/uniprotkb/P57744" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P57744", "url": "https://www.uniprot.org/uniprotkb/P57744" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P57744", "url": "https://www.uniprot.org/uniprotkb/P57744" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P57744", "url": "https://www.uniprot.org/uniprotkb/P57744" } ], "pmid": "" }, { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "P57744", "url": "https://www.uniprot.org/uniprotkb/P57744" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P57744", "url": "https://www.uniprot.org/uniprotkb/P57744" } ], "pmid": "" }, { "name": "protein transporter activity", "id": "GO:0140318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140318", "evidence": [ { "database": "UniProtKB", "id": "P57744", "url": "https://www.uniprot.org/uniprotkb/P57744" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P57744-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000007348", "url": "https://www.yeastgenome.org/locus/S000007348" }, { "database": "iPTMnet", "id": "P57744", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P57744" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P57744-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P57744", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P57744" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P57744-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000007348", "url": "https://www.yeastgenome.org/locus/S000007348" }, { "database": "iPTMnet", "id": "P57744", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P57744" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P57744-1" }, { "uniprot_canonical_ac": "P69771-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 204, "chemical_mass": 23091.0, "gene_names": "DID2;CHM1;DID2;FTI1;VPL30;VPS46", "protein_name": "Vacuolar protein-sorting-associated protein 46", "disease": [ { "disease_id": "DOID:0060277", "name": "pontocerebellar hypoplasia type 8", "description": "A pontocerebellar hypoplasia that is characterized by delayed psychomotor development, chorea, hypotonia, spasticity and visual defects, has_material_basis_in autosomal recessive inheritance of mutation in the CHMP1A gene.", "url": "https://disease-ontology.org/term/DOID:0060277", "evidence": [ { "id": "0060277", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060277" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "pmid": "" }, { "name": "endosome transport via multivesicular body sorting pathway", "id": "GO:0032509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032509", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "pmid": "" }, { "name": "ESCRT III complex assembly", "id": "GO:1904902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904902", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P69771-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006435", "url": "https://www.yeastgenome.org/locus/S000006435" }, { "database": "iPTMnet", "id": "P69771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P69771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P69771-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P69771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P69771" }, { "database": "SGD", "id": "S000006435", "url": "https://www.yeastgenome.org/locus/S000006435" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P69771-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Ser93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006435", "url": "https://www.yeastgenome.org/locus/S000006435" }, { "database": "iPTMnet", "id": "P69771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P69771" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P69771-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Arg198", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "D", "comment": "Impairs sorting.", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" }, { "database": "PubMed", "id": "17928861", "url": "https://glygen.org/publication/PubMed/17928861" } ] } ] }, { "uniprot_canonical_ac": "P69771-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Leu199", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Impairs sorting; when associated with D-202.", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" }, { "database": "PubMed", "id": "17928861", "url": "https://glygen.org/publication/PubMed/17928861" } ] } ] }, { "uniprot_canonical_ac": "P69771-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Leu202", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Impairs sorting; when associated with D-199.", "evidence": [ { "database": "UniProtKB", "id": "P69771", "url": "https://www.uniprot.org/uniprotkb/P69771" }, { "database": "PubMed", "id": "17928861", "url": "https://glygen.org/publication/PubMed/17928861" } ] } ] } ], "record_id": "P69771-1" }, { "uniprot_canonical_ac": "Q00453-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q00453", "url": "https://www.uniprot.org/uniprotkb/Q00453" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 211, "chemical_mass": 23855.0, "gene_names": "RGM1;RGM1;YM8010.12C", "protein_name": "Probable transcription repressor protein RGM1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q00453", "url": "https://www.uniprot.org/uniprotkb/Q00453" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q00453", "url": "https://www.uniprot.org/uniprotkb/Q00453" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q00453", "url": "https://www.uniprot.org/uniprotkb/Q00453" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q00453", "url": "https://www.uniprot.org/uniprotkb/Q00453" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q00453", "url": "https://www.uniprot.org/uniprotkb/Q00453" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q00453", "url": "https://www.uniprot.org/uniprotkb/Q00453" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q00453", "url": "https://www.uniprot.org/uniprotkb/Q00453" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q00453", "url": "https://www.uniprot.org/uniprotkb/Q00453" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q00453-1" }, { "uniprot_canonical_ac": "Q02205-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 184, "chemical_mass": 20242.0, "gene_names": "MEH1;EGO1;GSE2;MEH1;YK106", "protein_name": "Protein MEH1", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "Ragulator complex", "id": "GO:0071986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071986", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "regulation of receptor recycling", "id": "GO:0001919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001919", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "positive regulation of TOR signaling", "id": "GO:0032008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032008", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "protein localization to vacuole", "id": "GO:0072665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072665", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" }, { "name": "microautophagy", "id": "GO:0016237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016237", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02205-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Thr130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Thr131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Thr134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Thr138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Thr140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Thr145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02205", "url": "https://www.uniprot.org/uniprotkb/Q02205" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Tyr27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02205-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001715", "url": "https://www.yeastgenome.org/locus/S000001715" }, { "database": "iPTMnet", "id": "Q02205", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02205" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q02205-1" }, { "uniprot_canonical_ac": "Q02256-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 364, "chemical_mass": 41185.0, "gene_names": "YVH1;YVH1", "protein_name": "Tyrosine-protein phosphatase YVH1", "disease": [], "molecular_function": [ { "name": "preribosome binding", "id": "GO:1990275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990275", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" }, { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" }, { "name": "ascospore wall assembly", "id": "GO:0030476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030476", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02256-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02256", "url": "https://www.uniprot.org/uniprotkb/Q02256" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q02256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02256" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001465", "url": "https://www.yeastgenome.org/locus/S000001465" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02256-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001465", "url": "https://www.yeastgenome.org/locus/S000001465" }, { "database": "iPTMnet", "id": "Q02256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02256" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02256-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02256" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001465", "url": "https://www.yeastgenome.org/locus/S000001465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02256-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02256" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001465", "url": "https://www.yeastgenome.org/locus/S000001465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02256-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Ser210", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001465", "url": "https://www.yeastgenome.org/locus/S000001465" }, { "database": "iPTMnet", "id": "Q02256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02256" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02256-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Ser212", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001465", "url": "https://www.yeastgenome.org/locus/S000001465" }, { "database": "iPTMnet", "id": "Q02256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02256" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02256-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Ser213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001465", "url": "https://www.yeastgenome.org/locus/S000001465" }, { "database": "iPTMnet", "id": "Q02256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02256" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02256-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Thr220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001465", "url": "https://www.yeastgenome.org/locus/S000001465" }, { "database": "iPTMnet", "id": "Q02256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02256" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02256-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Ser244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001465", "url": "https://www.yeastgenome.org/locus/S000001465" }, { "database": "iPTMnet", "id": "Q02256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02256" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02256-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02256", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02256" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "Q02256-1" }, { "uniprot_canonical_ac": "Q02574-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 474, "chemical_mass": 53146.0, "gene_names": "MEC3;L8003.15;MEC3;PIP3;PSO9", "protein_name": "DNA damage checkpoint control protein MEC3", "disease": [], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "mitotic intra-S DNA damage checkpoint signaling", "id": "GO:0031573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031573", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "telomere maintenance via recombination", "id": "GO:0000722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000722", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "meiotic DNA integrity checkpoint signaling", "id": "GO:0044778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044778", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "checkpoint clamp complex", "id": "GO:0030896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030896", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02574-1", "start_pos": "311", "end_pos": "311", "site_lbl": "Thr311", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004279", "url": "https://www.yeastgenome.org/locus/S000004279" }, { "database": "iPTMnet", "id": "Q02574", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02574" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02574-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Ser315", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004279", "url": "https://www.yeastgenome.org/locus/S000004279" }, { "database": "iPTMnet", "id": "Q02574", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02574" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02574-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Ser330", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004279", "url": "https://www.yeastgenome.org/locus/S000004279" }, { "database": "iPTMnet", "id": "Q02574", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02574" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02574-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Ser368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004279", "url": "https://www.yeastgenome.org/locus/S000004279" }, { "database": "iPTMnet", "id": "Q02574", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02574" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02574-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004279", "url": "https://www.yeastgenome.org/locus/S000004279" }, { "database": "iPTMnet", "id": "Q02574", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02574" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02574-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "Q02574", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02574" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "Q02574", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02574" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02574", "url": "https://www.uniprot.org/uniprotkb/Q02574" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004279", "url": "https://www.yeastgenome.org/locus/S000004279" }, { "database": "iPTMnet", "id": "Q02574", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02574" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02574-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02574", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02574" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] } ], "record_id": "Q02574-1" }, { "uniprot_canonical_ac": "Q02629-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 959, "chemical_mass": 99988.0, "gene_names": "NUP100;NSP100;NUP100;YKL336", "protein_name": "Nucleoporin NUP100/NSP100", "disease": [ { "disease_id": "DOID:5603", "name": "T-cell acute lymphoblastic leukemia", "description": "An acute lymphoblastic leukemia that is characterized by too many T-cell lymphoblasts found in the bone marrow and blood.", "url": "https://disease-ontology.org/term/DOID:5603", "evidence": [ { "id": "5603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5603" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "nuclear pore cytoplasmic filaments", "id": "GO:0044614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044614", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "nuclear pore central transport channel", "id": "GO:0044613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044613", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "mRNA export from nucleus in response to heat stress", "id": "GO:0031990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031990", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000973", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "telomere tethering at nuclear periphery", "id": "GO:0034398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034398", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "protein localization to nuclear inner membrane", "id": "GO:0036228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036228", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "NLS-bearing protein import into nucleus", "id": "GO:0006607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006607", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "membraneless organelle assembly", "id": "GO:0140694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140694", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" }, { "name": "regulation of tRNA export from nucleus", "id": "GO:2000238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000238", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02629-1", "start_pos": "643", "end_pos": "643", "site_lbl": "Ser643", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "660", "end_pos": "660", "site_lbl": "Ser660", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "685", "end_pos": "685", "site_lbl": "Ser685", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "736", "end_pos": "736", "site_lbl": "Thr736", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "739", "end_pos": "739", "site_lbl": "Thr739", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "741", "end_pos": "741", "site_lbl": "Ser741", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "749", "end_pos": "749", "site_lbl": "Ser749", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "763", "end_pos": "763", "site_lbl": "Ser763", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "766", "end_pos": "766", "site_lbl": "Thr766", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "775", "end_pos": "775", "site_lbl": "Ser775", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "776", "end_pos": "776", "site_lbl": "Thr776", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "781", "end_pos": "781", "site_lbl": "Ser781", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "783", "end_pos": "783", "site_lbl": "Ser783", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02629", "url": "https://www.uniprot.org/uniprotkb/Q02629" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "787", "end_pos": "787", "site_lbl": "Ser787", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" }, { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02629-1", "start_pos": "788", "end_pos": "788", "site_lbl": "Thr788", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02629" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001551", "url": "https://www.yeastgenome.org/locus/S000001551" } ] } ] } ], "record_id": "Q02629-1" }, { "uniprot_canonical_ac": "Q02630-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1113, "chemical_mass": 116234.0, "gene_names": "NUP116;NSP116;NUP116;YM9532.12C", "protein_name": "Nucleoporin NUP116/NSP116", "disease": [ { "disease_id": "DOID:5603", "name": "T-cell acute lymphoblastic leukemia", "description": "An acute lymphoblastic leukemia that is characterized by too many T-cell lymphoblasts found in the bone marrow and blood.", "url": "https://disease-ontology.org/term/DOID:5603", "evidence": [ { "id": "5603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5603" } ], "weight": 0.0 } ], "biological_process": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "nuclear pore organization", "id": "GO:0006999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006999", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "tRNA export from nucleus", "id": "GO:0006409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006409", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000973", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "telomere tethering at nuclear periphery", "id": "GO:0034398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034398", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "nuclear pore cytoplasmic filaments", "id": "GO:0044614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044614", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" }, { "name": "nuclear pore central transport channel", "id": "GO:0044613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044613", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02630-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Ser752", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 752, "start_aa": "Ser", "end_pos": 752, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser752", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q02630", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q02630" } ] } ] }, { "uniprot_canonical_ac": "Q02630-1", "start_pos": "755", "end_pos": "755", "site_lbl": "Thr755", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 755, "start_aa": "Thr", "end_pos": 755, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr755", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q02630", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q02630" } ] } ] }, { "uniprot_canonical_ac": "Q02630-1", "start_pos": "761", "end_pos": "761", "site_lbl": "Ser761", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 761, "start_aa": "Ser", "end_pos": 761, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser761", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q02630", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q02630" } ] } ] }, { "uniprot_canonical_ac": "Q02630-1", "start_pos": "767", "end_pos": "767", "site_lbl": "Ser767", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 767, "start_aa": "Ser", "end_pos": 767, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser767", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q02630", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q02630" } ] } ] }, { "uniprot_canonical_ac": "Q02630-1", "start_pos": "816", "end_pos": "816", "site_lbl": "Ser816", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004650", "url": "https://www.yeastgenome.org/locus/S000004650" }, { "database": "iPTMnet", "id": "Q02630", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02630" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02630-1", "start_pos": "818", "end_pos": "818", "site_lbl": "Ser818", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004650", "url": "https://www.yeastgenome.org/locus/S000004650" }, { "database": "iPTMnet", "id": "Q02630", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02630" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02630-1", "start_pos": "886", "end_pos": "886", "site_lbl": "Ser886", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02630", "url": "https://www.uniprot.org/uniprotkb/Q02630" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02630", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02630" }, { "database": "SGD", "id": "S000004650", "url": "https://www.yeastgenome.org/locus/S000004650" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02630-1", "start_pos": "921", "end_pos": "921", "site_lbl": "Ser921", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004650", "url": "https://www.yeastgenome.org/locus/S000004650" }, { "database": "iPTMnet", "id": "Q02630", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02630" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02630-1", "start_pos": "947", "end_pos": "947", "site_lbl": "Ser947", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004650", "url": "https://www.yeastgenome.org/locus/S000004650" }, { "database": "iPTMnet", "id": "Q02630", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02630" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q02630-1" }, { "uniprot_canonical_ac": "Q02642-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 157, "chemical_mass": 17020.0, "gene_names": "EGD1;EGD1", "protein_name": "Nascent polypeptide-associated complex subunit beta-1", "disease": [], "biological_process": [ { "name": "'de novo' cotranslational protein folding", "id": "GO:0051083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051083", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" }, { "name": "cotranslational protein targeting to membrane", "id": "GO:0006613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006613", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" }, { "name": "nascent polypeptide-associated complex", "id": "GO:0005854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005854", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02642-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Thr151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02642", "url": "https://www.uniprot.org/uniprotkb/Q02642" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q02642", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02642" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005958", "url": "https://www.yeastgenome.org/locus/S000005958" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02642-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02642", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02642" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005958", "url": "https://www.yeastgenome.org/locus/S000005958" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02642-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005958", "url": "https://www.yeastgenome.org/locus/S000005958" }, { "database": "iPTMnet", "id": "Q02642", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02642" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02642-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02642", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02642" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005958", "url": "https://www.yeastgenome.org/locus/S000005958" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02642-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Thr42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005958", "url": "https://www.yeastgenome.org/locus/S000005958" }, { "database": "iPTMnet", "id": "Q02642", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02642" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02642-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005958", "url": "https://www.yeastgenome.org/locus/S000005958" }, { "database": "iPTMnet", "id": "Q02642", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02642" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02642-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Thr55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005958", "url": "https://www.yeastgenome.org/locus/S000005958" }, { "database": "iPTMnet", "id": "Q02642", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02642" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q02642-1" }, { "uniprot_canonical_ac": "Q02725-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 835, "chemical_mass": 96553.0, "gene_names": "VTC3;PHM2;VTC3", "protein_name": "Vacuolar transporter chaperone 3 complex subunit 3", "disease": [], "biological_process": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "vacuole fusion, non-autophagic", "id": "GO:0042144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042144", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "engulfment of target by autophagosome", "id": "GO:0061736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061736", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "polyphosphate metabolic process", "id": "GO:0006797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006797", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "intracellular phosphate ion homeostasis", "id": "GO:0030643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030643", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "microautophagy", "id": "GO:0016237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016237", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "polyphosphate biosynthetic process", "id": "GO:0006799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006799", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" } ], "cellular_component": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "vacuolar transporter chaperone complex", "id": "GO:0033254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033254", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" } ], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" }, { "name": "inositol hexakisphosphate binding", "id": "GO:0000822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000822", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02725-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Thr183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Ser190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Thr191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Ser263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Ser270", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Ser274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Ser283", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Ser317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Thr321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Ser470", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Ser577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "589", "end_pos": "589", "site_lbl": "Ser589", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "592", "end_pos": "592", "site_lbl": "Ser592", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "598", "end_pos": "598", "site_lbl": "Thr598", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Thr599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "609", "end_pos": "609", "site_lbl": "Thr609", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Ser621", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "622", "end_pos": "622", "site_lbl": "Ser622", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02725", "url": "https://www.uniprot.org/uniprotkb/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "627", "end_pos": "627", "site_lbl": "Thr627", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "664", "end_pos": "664", "site_lbl": "Tyr664", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "665", "end_pos": "665", "site_lbl": "Ser665", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "670", "end_pos": "670", "site_lbl": "Ser670", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "672", "end_pos": "672", "site_lbl": "Ser672", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02725-1", "start_pos": "673", "end_pos": "673", "site_lbl": "Ser673", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02725", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02725" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005940", "url": "https://www.yeastgenome.org/locus/S000005940" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q02725-1" }, { "uniprot_canonical_ac": "Q02732-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 369, "chemical_mass": 42782.0, "gene_names": "CTF19;CTF19;LPB13W;MCM18", "protein_name": "Inner kinetochore subunit CTF19", "disease": [], "biological_process": [ { "name": "protein localization to chromosome, centromeric region", "id": "GO:0071459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071459", "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "pmid": "" }, { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "pmid": "" }, { "name": "establishment of mitotic sister chromatid cohesion", "id": "GO:0034087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034087", "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "pmid": "" }, { "name": "COMA complex", "id": "GO:0000817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000817", "evidence": [ { "database": "UniProtKB", "id": "Q02732", "url": "https://www.uniprot.org/uniprotkb/Q02732" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02732-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Thr303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005939", "url": "https://www.yeastgenome.org/locus/S000005939" }, { "database": "iPTMnet", "id": "Q02732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02732" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02732-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005939", "url": "https://www.yeastgenome.org/locus/S000005939" }, { "database": "iPTMnet", "id": "Q02732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02732" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q02732-1" }, { "uniprot_canonical_ac": "Q02792-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1006, "chemical_mass": 115934.0, "gene_names": "RAT1;HKE1;RAT1;TAP1;XRN2", "protein_name": "5'-3' exoribonuclease 2", "disease": [ { "disease_id": "DOID:0080202", "name": "adenoid cystic carcinoma", "description": "An adenocarcinoma that is characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells.", "url": "https://disease-ontology.org/term/DOID:0080202", "evidence": [ { "id": "0080202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080202" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:1967", "name": "leiomyosarcoma", "description": "A smooth muscle cancer that can arise almost anywhere in the body, but is most common in the uterus, abdomen, or pelvis.", "url": "https://disease-ontology.org/term/DOID:1967", "evidence": [ { "id": "1967", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1967" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000448", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "negative regulation of transcription elongation by RNA polymerase II", "id": "GO:0034244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034244", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "NAD-cap decapping", "id": "GO:0110155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110155", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "sno(s)RNA processing", "id": "GO:0043144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043144", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "positive regulation of termination of RNA polymerase II transcription", "id": "GO:1904595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904595", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription, poly(A)-coupled", "id": "GO:0030846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030846", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription, exosome-dependent", "id": "GO:0030847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030847", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "5'-3' RNA exonuclease activity", "id": "GO:0004534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004534", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02792-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Thr161", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "449", "end_pos": "449", "site_lbl": "Ser449", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005574", "url": "https://www.yeastgenome.org/locus/S000005574" }, { "database": "iPTMnet", "id": "Q02792", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02792" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Ser487", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005574", "url": "https://www.yeastgenome.org/locus/S000005574" }, { "database": "iPTMnet", "id": "Q02792", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02792" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "543", "end_pos": "543", "site_lbl": "Ser543", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005574", "url": "https://www.yeastgenome.org/locus/S000005574" }, { "database": "iPTMnet", "id": "Q02792", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02792" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "565", "end_pos": "565", "site_lbl": "Ser565", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005574", "url": "https://www.yeastgenome.org/locus/S000005574" }, { "database": "iPTMnet", "id": "Q02792", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02792" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "571", "end_pos": "571", "site_lbl": "Ser571", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005574", "url": "https://www.yeastgenome.org/locus/S000005574" }, { "database": "iPTMnet", "id": "Q02792", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02792" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "574", "end_pos": "574", "site_lbl": "Ser574", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02792", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02792" }, { "database": "SGD", "id": "S000005574", "url": "https://www.yeastgenome.org/locus/S000005574" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "583", "end_pos": "583", "site_lbl": "Ser583", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005574", "url": "https://www.yeastgenome.org/locus/S000005574" }, { "database": "iPTMnet", "id": "Q02792", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02792" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Asp235", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abrogates exonuclease activity and impairs termination of transcription by RNA polymerase II.", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" }, { "database": "PubMed", "id": "15565157", "url": "https://glygen.org/publication/PubMed/15565157" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "518", "end_pos": "518", "site_lbl": "His518", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "Causes mislocalization to the cytoplasm and suppresses the requirement for XRN1 function.", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" }, { "database": "PubMed", "id": "9315672", "url": "https://glygen.org/publication/PubMed/9315672" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "520", "end_pos": "520", "site_lbl": "Leu520", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "Suppresses the requirement for XRN1 function.", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" }, { "database": "PubMed", "id": "9315672", "url": "https://glygen.org/publication/PubMed/9315672" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "534", "end_pos": "534", "site_lbl": "Lys534", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Causes mislocalization to the cytoplasm; when associated with A-535 and A-537.", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" }, { "database": "PubMed", "id": "9315672", "url": "https://glygen.org/publication/PubMed/9315672" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "535", "end_pos": "535", "site_lbl": "Lys535", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Causes mislocalization to the cytoplasm; when associated with A-534 and A-537.", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" }, { "database": "PubMed", "id": "9315672", "url": "https://glygen.org/publication/PubMed/9315672" } ] }, { "sequence_org": "K", "sequence_mut": "N", "comment": "Causes mislocalization to the cytoplasm and suppresses the requirement for XRN1 function.", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" }, { "database": "PubMed", "id": "9315672", "url": "https://glygen.org/publication/PubMed/9315672" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "537", "end_pos": "537", "site_lbl": "Lys537", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Causes mislocalization to the cytoplasm; when associated with A-534 and A-535.", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" }, { "database": "PubMed", "id": "9315672", "url": "https://glygen.org/publication/PubMed/9315672" } ] }, { "sequence_org": "K", "sequence_mut": "E", "comment": "Causes mislocalization to the cytoplasm and suppresses the requirement for XRN1 function.", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" }, { "database": "PubMed", "id": "9315672", "url": "https://glygen.org/publication/PubMed/9315672" } ] } ] }, { "uniprot_canonical_ac": "Q02792-1", "start_pos": "683", "end_pos": "683", "site_lbl": "Tyr683", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "H", "comment": "In allele TAP1-1; activates transcription of the promoter-defective yeast SUP4 tRNA(Tyr) allele SUP4A53T61.", "evidence": [ { "database": "UniProtKB", "id": "Q02792", "url": "https://www.uniprot.org/uniprotkb/Q02792" } ] } ] } ], "record_id": "Q02792-1" }, { "uniprot_canonical_ac": "Q02805-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 837, "chemical_mass": 92349.0, "gene_names": "ROD1;ART4;OR26.08;ROD1", "protein_name": "Protein ROD1", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:14525", "name": "Reye syndrome", "description": "A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.", "url": "https://disease-ontology.org/term/DOID:14525", "evidence": [ { "id": "14525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14525" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to glucose stimulus", "id": "GO:0071333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071333", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" } ], "pmid": "" }, { "name": "positive regulation of receptor internalization", "id": "GO:0002092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002092", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" } ], "pmid": "" }, { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02805-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Thr412", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 412, "start_aa": "Thr", "end_pos": 412, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr412", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q02805", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q02805" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Ser416", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 416, "start_aa": "Ser", "end_pos": 416, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser416", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q02805", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q02805" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "421", "end_pos": "421", "site_lbl": "Ser421", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 421, "start_aa": "Ser", "end_pos": 421, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser421", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q02805", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q02805" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Ser426", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 426, "start_aa": "Ser", "end_pos": 426, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser426", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q02805", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q02805" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "428", "end_pos": "428", "site_lbl": "Ser428", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 428, "start_aa": "Ser", "end_pos": 428, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser428", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q02805", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q02805" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Ser429", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 429, "start_aa": "Ser", "end_pos": 429, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser429", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q02805", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q02805" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Thr125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "26920760", "url": "https://glygen.org/publication/PubMed/26920760" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Thr139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Ser315", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "26920760", "url": "https://glygen.org/publication/PubMed/26920760" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "326", "end_pos": "326", "site_lbl": "Thr326", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Thr328", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Ser436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "447", "end_pos": "447", "site_lbl": "Ser447", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "17949685", "url": "https://glygen.org/publication/PubMed/17949685" }, { "database": "PubMed", "id": "26920760", "url": "https://glygen.org/publication/PubMed/26920760" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "536", "end_pos": "536", "site_lbl": "Ser536", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Ser553", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "559", "end_pos": "559", "site_lbl": "Ser559", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Ser586", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "602", "end_pos": "602", "site_lbl": "Ser602", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Ser604", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "606", "end_pos": "606", "site_lbl": "Thr606", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "608", "end_pos": "608", "site_lbl": "Ser608", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Ser613", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "623", "end_pos": "623", "site_lbl": "Ser623", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "625", "end_pos": "625", "site_lbl": "Thr625", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Ser626", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "634", "end_pos": "634", "site_lbl": "Thr634", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "637", "end_pos": "637", "site_lbl": "Ser637", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "641", "end_pos": "641", "site_lbl": "Ser641", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "26920760", "url": "https://glygen.org/publication/PubMed/26920760" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "642", "end_pos": "642", "site_lbl": "Tyr642", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Ser684", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "685", "end_pos": "685", "site_lbl": "Thr685", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "686", "end_pos": "686", "site_lbl": "Ser686", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "687", "end_pos": "687", "site_lbl": "Ser687", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "694", "end_pos": "694", "site_lbl": "Ser694", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "697", "end_pos": "697", "site_lbl": "Ser697", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "698", "end_pos": "698", "site_lbl": "Ser698", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "704", "end_pos": "704", "site_lbl": "Ser704", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "705", "end_pos": "705", "site_lbl": "Ser705", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "706", "end_pos": "706", "site_lbl": "Ser706", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "26920760", "url": "https://glygen.org/publication/PubMed/26920760" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "708", "end_pos": "708", "site_lbl": "Thr708", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Ser713", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "720", "end_pos": "720", "site_lbl": "Ser720", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "26920760", "url": "https://glygen.org/publication/PubMed/26920760" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "722", "end_pos": "722", "site_lbl": "Ser722", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "723", "end_pos": "723", "site_lbl": "Ser723", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "725", "end_pos": "725", "site_lbl": "Ser725", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02805", "url": "https://www.uniprot.org/uniprotkb/Q02805" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "736", "end_pos": "736", "site_lbl": "Ser736", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "737", "end_pos": "737", "site_lbl": "Ser737", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "781", "end_pos": "781", "site_lbl": "Ser781", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "26920760", "url": "https://glygen.org/publication/PubMed/26920760" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "803", "end_pos": "803", "site_lbl": "Ser803", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "807", "end_pos": "807", "site_lbl": "Ser807", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "26920760", "url": "https://glygen.org/publication/PubMed/26920760" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "810", "end_pos": "810", "site_lbl": "Ser810", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "813", "end_pos": "813", "site_lbl": "Ser813", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "815", "end_pos": "815", "site_lbl": "Ser815", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "821", "end_pos": "821", "site_lbl": "Thr821", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "823", "end_pos": "823", "site_lbl": "Ser823", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02805-1", "start_pos": "832", "end_pos": "832", "site_lbl": "Thr832", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005544", "url": "https://www.yeastgenome.org/locus/S000005544" }, { "database": "iPTMnet", "id": "Q02805", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "Q02805-1" }, { "uniprot_canonical_ac": "Q02931-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 896, "chemical_mass": 101237.0, "gene_names": "NAN1;NAN1;UTP17", "protein_name": "NET1-associated nuclear protein 1", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0111169", "name": "subcortical band heterotopia", "description": "A congenital nervous system abnormality characterized by migration of neurons to ectopic locations in the brain where the neurons form areas that appear as band-like clusters of white tissue underneath the gray tissue of the cerebral cortex.", "url": "https://disease-ontology.org/term/DOID:0111169", "evidence": [ { "id": "0111169", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111169" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of rRNA processing", "id": "GO:2000234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000234", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "U3 snoRNA binding", "id": "GO:0034511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034511", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "rDNA heterochromatin", "id": "GO:0033553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033553", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "t-UTP complex", "id": "GO:0034455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034455", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q02931", "url": "https://www.uniprot.org/uniprotkb/Q02931" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02931-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006047", "url": "https://www.yeastgenome.org/locus/S000006047" }, { "database": "iPTMnet", "id": "Q02931", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02931" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02931-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006047", "url": "https://www.yeastgenome.org/locus/S000006047" }, { "database": "iPTMnet", "id": "Q02931", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02931" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02931-1", "start_pos": "413", "end_pos": "413", "site_lbl": "Ser413", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006047", "url": "https://www.yeastgenome.org/locus/S000006047" }, { "database": "iPTMnet", "id": "Q02931", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02931" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02931-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02931", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02931" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006047", "url": "https://www.yeastgenome.org/locus/S000006047" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02931-1", "start_pos": "817", "end_pos": "817", "site_lbl": "Ser817", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006047", "url": "https://www.yeastgenome.org/locus/S000006047" }, { "database": "iPTMnet", "id": "Q02931", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02931" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q02931-1" }, { "uniprot_canonical_ac": "Q02948-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 557, "chemical_mass": 63261.0, "gene_names": "VPS30;APG6;ATG6;LPH7;VPS30;VPT30", "protein_name": "Vacuolar protein sorting-associated protein 30", "disease": [ { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:0080998", "name": "acute necrotizing pancreatitis", "description": "An acute pancreatitis that is characterized by one or more areas of necrosis in the pancreas with varying degree of involvement of the surrounding tissues or organ systems.", "url": "https://disease-ontology.org/term/DOID:0080998", "evidence": [ { "id": "0080998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080998" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:12010", "name": "anterior ischemic optic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:12010", "evidence": [ { "id": "12010", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12010" } ], "weight": 0.0 }, { "disease_id": "DOID:1440", "name": "Machado-Joseph disease", "description": "An autosomal dominant cerebellar ataxia that is characterized by slow degeneration of the hindbrain and has_material_basis_in expansion of CAG triplet repeats (glutamine) in the ATXN3 gene.", "url": "https://disease-ontology.org/term/DOID:1440", "evidence": [ { "id": "1440", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1440" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 }, { "disease_id": "DOID:3454", "name": "brain infarction", "description": "A cerebrovascular disease that is characterized by tissue necrosis located_in the brain, resulting from inadequate blood flow through the brain.", "url": "https://disease-ontology.org/term/DOID:3454", "evidence": [ { "id": "3454", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3454" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:4914", "name": "esophagus adenocarcinoma", "description": "An esophageal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:4914", "evidence": [ { "id": "4914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4914" } ], "weight": 0.0 }, { "disease_id": "DOID:4928", "name": "intrahepatic cholangiocarcinoma", "description": "A cholangiocarcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree.", "url": "https://disease-ontology.org/term/DOID:4928", "evidence": [ { "id": "4928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4928" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:5199", "name": "ureteral obstruction", "description": "An urinary tract obstruction that is characterized by a blockage in one or both of the tubes (ureters) that carry urine from the kidneys to the bladder.", "url": "https://disease-ontology.org/term/DOID:5199", "evidence": [ { "id": "5199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5199" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:607", "name": "paraplegia", "description": "", "url": "https://disease-ontology.org/term/DOID:607", "evidence": [ { "id": "607", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:607" } ], "weight": 0.0 }, { "disease_id": "DOID:646", "name": "viral encephalitis", "description": "An encephalitis that involves inflammation of the brain caused by viral infection.", "url": "https://disease-ontology.org/term/DOID:646", "evidence": [ { "id": "646", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:646" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:8283", "name": "peritonitis", "description": "A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.", "url": "https://disease-ontology.org/term/DOID:8283", "evidence": [ { "id": "8283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8283" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 }, { "disease_id": "DOID:8677", "name": "perinatal necrotizing enterocolitis", "description": "", "url": "https://disease-ontology.org/term/DOID:8677", "evidence": [ { "id": "8677", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8677" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:90", "name": "degenerative disc disease", "description": "A bone deterioration disease that has_material_basis_in gradual dehydration and tears located_in intervertebral disc.", "url": "https://disease-ontology.org/term/DOID:90", "evidence": [ { "id": "90", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:90" } ], "weight": 0.0 }, { "disease_id": "DOID:9206", "name": "Barrett's esophagus", "description": "An esophageal disease characterized by a change of normal esophageal squamous epithelium to a columnar and intestinal-type epithelium.", "url": "https://disease-ontology.org/term/DOID:9206", "evidence": [ { "id": "9206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9206" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cellular response to potassium ion starvation", "id": "GO:0051365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051365", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "phosphatidylinositol biosynthetic process", "id": "GO:0006661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006661", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class III, type I", "id": "GO:0034271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034271", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class III, type II", "id": "GO:0034272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034272", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "vacuole-isolation membrane contact site", "id": "GO:0120095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120095", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase binding", "id": "GO:0043548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q02948-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02948" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006041", "url": "https://www.yeastgenome.org/locus/S000006041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02948-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Thr124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02948" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006041", "url": "https://www.yeastgenome.org/locus/S000006041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02948-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02948" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006041", "url": "https://www.yeastgenome.org/locus/S000006041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02948-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006041", "url": "https://www.yeastgenome.org/locus/S000006041" }, { "database": "iPTMnet", "id": "Q02948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02948" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q02948-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q02948", "url": "https://www.uniprot.org/uniprotkb/Q02948" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q02948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02948" }, { "database": "SGD", "id": "S000006041", "url": "https://www.yeastgenome.org/locus/S000006041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02948-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Thr257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02948" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006041", "url": "https://www.yeastgenome.org/locus/S000006041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02948-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02948" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006041", "url": "https://www.yeastgenome.org/locus/S000006041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02948-1", "start_pos": "540", "end_pos": "540", "site_lbl": "Ser540", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02948" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q02948-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Ser544", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q02948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02948" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006041", "url": "https://www.yeastgenome.org/locus/S000006041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q02948-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006041", "url": "https://www.yeastgenome.org/locus/S000006041" }, { "database": "iPTMnet", "id": "Q02948", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02948" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] } ], "record_id": "Q02948-1" }, { "uniprot_canonical_ac": "Q03018-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1630, "chemical_mass": 187447.0, "gene_names": "ESP1;ESP1", "protein_name": "Separin", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "biological_process": [ { "name": "meiotic chromosome separation", "id": "GO:0051307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051307", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "negative regulation of protein localization to nucleolus", "id": "GO:1904750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904750", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "positive regulation of exit from mitosis", "id": "GO:0031536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031536", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "regulation of mitotic spindle elongation", "id": "GO:0032888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032888", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "meiosis II", "id": "GO:0007135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007135", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "positive regulation of metaphase/anaphase transition of meiotic cell cycle", "id": "GO:1902104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902104", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" }, { "name": "mitotic spindle pole body", "id": "GO:0044732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044732", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "Q03018", "url": "https://www.uniprot.org/uniprotkb/Q03018" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03018-1", "start_pos": "1027", "end_pos": "1027", "site_lbl": "Ser1027", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003330", "url": "https://www.yeastgenome.org/locus/S000003330" }, { "database": "iPTMnet", "id": "Q03018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03018" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q03018-1", "start_pos": "1032", "end_pos": "1032", "site_lbl": "Ser1032", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003330", "url": "https://www.yeastgenome.org/locus/S000003330" }, { "database": "iPTMnet", "id": "Q03018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03018" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03018-1", "start_pos": "1034", "end_pos": "1034", "site_lbl": "Thr1034", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003330", "url": "https://www.yeastgenome.org/locus/S000003330" }, { "database": "iPTMnet", "id": "Q03018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03018" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03018-1", "start_pos": "1091", "end_pos": "1091", "site_lbl": "Thr1091", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003330", "url": "https://www.yeastgenome.org/locus/S000003330" }, { "database": "iPTMnet", "id": "Q03018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03018" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "Q03018-1", "start_pos": "1092", "end_pos": "1092", "site_lbl": "Ser1092", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003330", "url": "https://www.yeastgenome.org/locus/S000003330" }, { "database": "iPTMnet", "id": "Q03018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03018" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "Q03018-1", "start_pos": "1204", "end_pos": "1204", "site_lbl": "Ser1204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003330", "url": "https://www.yeastgenome.org/locus/S000003330" }, { "database": "iPTMnet", "id": "Q03018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03018" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03018-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003330", "url": "https://www.yeastgenome.org/locus/S000003330" }, { "database": "iPTMnet", "id": "Q03018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03018" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03018-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Thr16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003330", "url": "https://www.yeastgenome.org/locus/S000003330" }, { "database": "iPTMnet", "id": "Q03018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03018" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03018-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03018" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003330", "url": "https://www.yeastgenome.org/locus/S000003330" } ] } ] } ], "record_id": "Q03018-1" }, { "uniprot_canonical_ac": "Q03048-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 143, "chemical_mass": 15901.0, "gene_names": "COF1;COF1;L0596", "protein_name": "Cofilin", "disease": [ { "disease_id": "DOID:0050562", "name": "West syndrome", "description": "An infancy electroclinical syndrome that is characterized by infantile spasms, hypsarrhythmia on electroencephalogram and intellectual disability.", "url": "https://disease-ontology.org/term/DOID:0050562", "evidence": [ { "id": "0050562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050562" } ], "weight": 0.0 }, { "disease_id": "DOID:0050731", "name": "vitamin B12 deficiency", "description": "A vitamin metabolic disorder that results from low blood levels of vitamin B12.", "url": "https://disease-ontology.org/term/DOID:0050731", "evidence": [ { "id": "0050731", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050731" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0110934", "name": "nemaline myopathy 7", "description": "A nemaline myopathy characterized by very early onset of hypotonia and delayed motor development that has_material_basis_in homozygous mutation in the CFL2 gene on chromosome 14q13.", "url": "https://disease-ontology.org/term/DOID:0110934", "evidence": [ { "id": "0110934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110934" } ], "weight": 0.0 }, { "disease_id": "DOID:11457", "name": "brain compression", "description": "A brain disease that is characterized by pressure on the intracranial tissues by an effusion of blood or cerebrospinal fluid, an abscess, a neoplasm, a depressed fracture of the skull, or edema of the brain.", "url": "https://disease-ontology.org/term/DOID:11457", "evidence": [ { "id": "11457", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11457" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:1875", "name": "impotence", "description": "A sexual dysfunction that is characterized by persistent or recurrent inability to achieve or to maintain an erection during sexual activity.", "url": "https://disease-ontology.org/term/DOID:1875", "evidence": [ { "id": "1875", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1875" } ], "weight": 0.0 }, { "disease_id": "DOID:4948", "name": "gallbladder carcinoma", "description": "A gallbladder cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4948", "evidence": [ { "id": "4948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4948" } ], "weight": 0.0 }, { "disease_id": "DOID:5199", "name": "ureteral obstruction", "description": "An urinary tract obstruction that is characterized by a blockage in one or both of the tubes (ureters) that carry urine from the kidneys to the bladder.", "url": "https://disease-ontology.org/term/DOID:5199", "evidence": [ { "id": "5199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5199" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" }, { "name": "actin filament severing", "id": "GO:0051014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051014", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" }, { "name": "actin filament depolymerization", "id": "GO:0030042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030042", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03048-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003973", "url": "https://www.yeastgenome.org/locus/S000003973" }, { "database": "iPTMnet", "id": "Q03048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03048" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03048-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003973", "url": "https://www.yeastgenome.org/locus/S000003973" }, { "database": "iPTMnet", "id": "Q03048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03048" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03048-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03048" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003973", "url": "https://www.yeastgenome.org/locus/S000003973" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03048-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003973", "url": "https://www.yeastgenome.org/locus/S000003973" }, { "database": "iPTMnet", "id": "Q03048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03048" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03048-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03048", "url": "https://www.uniprot.org/uniprotkb/Q03048" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q03048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03048" }, { "database": "PubMed", "id": "9753544", "url": "https://glygen.org/publication/PubMed/9753544" }, { "database": "SGD", "id": "S000003973", "url": "https://www.yeastgenome.org/locus/S000003973" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q03048-1" }, { "uniprot_canonical_ac": "Q03281-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03281", "url": "https://www.uniprot.org/uniprotkb/Q03281" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 663, "chemical_mass": 76377.0, "gene_names": "HEH2;D8035.2;HEH2", "protein_name": "Inner nuclear membrane protein HEH2", "disease": [ { "disease_id": "DOID:0110243", "name": "cataract 46 juvenile-onset", "description": "A cataract that has_material_basis_in homozygous mutation in the LEMD2 gene on chromosome 6p21.", "url": "https://disease-ontology.org/term/DOID:0110243", "evidence": [ { "id": "0110243", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110243" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q03281", "url": "https://www.uniprot.org/uniprotkb/Q03281" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q03281", "url": "https://www.uniprot.org/uniprotkb/Q03281" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "Q03281", "url": "https://www.uniprot.org/uniprotkb/Q03281" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "Q03281", "url": "https://www.uniprot.org/uniprotkb/Q03281" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear membrane organization", "id": "GO:0071763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071763", "evidence": [ { "database": "UniProtKB", "id": "Q03281", "url": "https://www.uniprot.org/uniprotkb/Q03281" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03281-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Thr110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03281", "url": "https://www.uniprot.org/uniprotkb/Q03281" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Thr152", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Thr157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Thr279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Ser280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002866", "url": "https://www.yeastgenome.org/locus/S000002866" }, { "database": "iPTMnet", "id": "Q03281", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03281" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03281-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Lys126", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "T", "comment": "Mislocalized to the endoplasmic reticulum.", "evidence": [ { "database": "UniProtKB", "id": "Q03281", "url": "https://www.uniprot.org/uniprotkb/Q03281" }, { "database": "PubMed", "id": "16929305", "url": "https://glygen.org/publication/PubMed/16929305" } ] } ] } ], "record_id": "Q03281-1" }, { "uniprot_canonical_ac": "Q03406-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 294, "chemical_mass": 33948.0, "gene_names": "SLD5;CDC105;SLD5", "protein_name": "DNA replication complex GINS protein SLD5", "disease": [], "cellular_component": [ { "name": "DNA replication preinitiation complex", "id": "GO:0031261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031261", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" } ], "pmid": "" }, { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" } ], "pmid": "" }, { "name": "GINS complex", "id": "GO:0000811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000811", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" } ], "pmid": "" }, { "name": "CMG complex", "id": "GO:0071162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071162", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03406-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Ser42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002897", "url": "https://www.yeastgenome.org/locus/S000002897" }, { "database": "iPTMnet", "id": "Q03406", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03406" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03406-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002897", "url": "https://www.yeastgenome.org/locus/S000002897" }, { "database": "iPTMnet", "id": "Q03406", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03406" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03406-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Lys150", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "In sld5-2; temperature-sensitive mutant. Defective in DNA replication.", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" }, { "database": "PubMed", "id": "12730134", "url": "https://glygen.org/publication/PubMed/12730134" } ] } ] }, { "uniprot_canonical_ac": "Q03406-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "P", "comment": "In sld5-8; temperature-sensitive mutant; in association with P-66. Defective in DNA replication.", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" }, { "database": "PubMed", "id": "12730134", "url": "https://glygen.org/publication/PubMed/12730134" } ] } ] }, { "uniprot_canonical_ac": "Q03406-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Leu293", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "In sld5-13; temperature-sensitive mutant. Defective in DNA replication.", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" }, { "database": "PubMed", "id": "12730134", "url": "https://glygen.org/publication/PubMed/12730134" } ] } ] }, { "uniprot_canonical_ac": "Q03406-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "P", "comment": "In sld5-8; temperature-sensitive mutant; in association with P-21. Defective in DNA replication.", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" }, { "database": "PubMed", "id": "12730134", "url": "https://glygen.org/publication/PubMed/12730134" } ] } ] }, { "uniprot_canonical_ac": "Q03406-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Trp67", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "R", "comment": "In sld5-12; temperature-sensitive mutant. Defective in DNA replication.", "evidence": [ { "database": "UniProtKB", "id": "Q03406", "url": "https://www.uniprot.org/uniprotkb/Q03406" }, { "database": "PubMed", "id": "12730134", "url": "https://glygen.org/publication/PubMed/12730134" } ] } ] } ], "record_id": "Q03406-1" }, { "uniprot_canonical_ac": "Q03435-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 203, "chemical_mass": 23857.0, "gene_names": "NHP10;HMO2;NHP10;YD8119.05C", "protein_name": "Non-histone protein 10", "disease": [ { "disease_id": "DOID:0080337", "name": "mitochondrial DNA depletion syndrome 15", "description": "A mitochondrial DNA depletion syndrome that is characterized by severe intrauterine growth restriction, neonatal-onset hypoglycemia and liver dysfunction, mitochondrial DNA depletion in liver and skeletal muscle, and abnormal mitochondrial morphology observed in skeletal muscle and has_material_basis_in homozygous mutation in the TFAM gene on chromosome 10q21.", "url": "https://disease-ontology.org/term/DOID:0080337", "evidence": [ { "id": "0080337", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080337" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:12934", "name": "Kearns-Sayre syndrome", "description": "A chronic progressive external ophthalmoplegia characterized by progressive external ophthalmoplegia, pigmentary retinopathy, and one or more of heart block, cerebellar ataxia, or a cerebrospinal fluid protein level above 100 mg/dl, that has_material_basis_in deletion of mitochondrial DNA. Onset is before 20 years of age.", "url": "https://disease-ontology.org/term/DOID:12934", "evidence": [ { "id": "12934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12934" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "pmid": "" }, { "name": "Ino80 complex", "id": "GO:0031011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "pmid": "" }, { "name": "telomere maintenance via recombination", "id": "GO:0000722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000722", "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "pmid": "" } ], "molecular_function": [ { "name": "heteroduplex DNA loop binding", "id": "GO:0000404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000404", "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "pmid": "" }, { "name": "DNA end binding", "id": "GO:0045027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045027", "evidence": [ { "database": "UniProtKB", "id": "Q03435", "url": "https://www.uniprot.org/uniprotkb/Q03435" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03435-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002160", "url": "https://www.yeastgenome.org/locus/S000002160" }, { "database": "iPTMnet", "id": "Q03435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03435" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03435-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Tyr150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03435" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002160", "url": "https://www.yeastgenome.org/locus/S000002160" } ] } ] }, { "uniprot_canonical_ac": "Q03435-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Ser162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002160", "url": "https://www.yeastgenome.org/locus/S000002160" }, { "database": "iPTMnet", "id": "Q03435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03435" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03435-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002160", "url": "https://www.yeastgenome.org/locus/S000002160" }, { "database": "iPTMnet", "id": "Q03435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03435" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03435-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002160", "url": "https://www.yeastgenome.org/locus/S000002160" }, { "database": "iPTMnet", "id": "Q03435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03435" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03435-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03435" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002160", "url": "https://www.yeastgenome.org/locus/S000002160" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03435-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03435" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002160", "url": "https://www.yeastgenome.org/locus/S000002160" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03435-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03435" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000002160", "url": "https://www.yeastgenome.org/locus/S000002160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03435-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002160", "url": "https://www.yeastgenome.org/locus/S000002160" }, { "database": "iPTMnet", "id": "Q03435", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03435" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q03435-1" }, { "uniprot_canonical_ac": "Q03446-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03446", "url": "https://www.uniprot.org/uniprotkb/Q03446" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 210, "chemical_mass": 24211.0, "gene_names": "RCR2;RCR2;SSH5;YD8119.09", "protein_name": "Protein RCR2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q03446", "url": "https://www.uniprot.org/uniprotkb/Q03446" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "Q03446", "url": "https://www.uniprot.org/uniprotkb/Q03446" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "Q03446", "url": "https://www.uniprot.org/uniprotkb/Q03446" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "Q03446", "url": "https://www.uniprot.org/uniprotkb/Q03446" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q03446", "url": "https://www.uniprot.org/uniprotkb/Q03446" } ], "pmid": "" } ], "biological_process": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q03446", "url": "https://www.uniprot.org/uniprotkb/Q03446" } ], "pmid": "" }, { "name": "protein localization to vacuole", "id": "GO:0072665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072665", "evidence": [ { "database": "UniProtKB", "id": "Q03446", "url": "https://www.uniprot.org/uniprotkb/Q03446" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03446-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002410", "url": "https://www.yeastgenome.org/locus/S000002410" }, { "database": "iPTMnet", "id": "Q03446", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03446" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03446-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Ser143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002410", "url": "https://www.yeastgenome.org/locus/S000002410" }, { "database": "iPTMnet", "id": "Q03446", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03446" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03446-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03446", "url": "https://www.uniprot.org/uniprotkb/Q03446" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q03446", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03446" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000002410", "url": "https://www.yeastgenome.org/locus/S000002410" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03446-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Ser163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002410", "url": "https://www.yeastgenome.org/locus/S000002410" }, { "database": "iPTMnet", "id": "Q03446", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03446" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03446-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03446", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03446" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002410", "url": "https://www.yeastgenome.org/locus/S000002410" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03446-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Thr191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03446", "url": "https://www.uniprot.org/uniprotkb/Q03446" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q03446", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03446" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002410", "url": "https://www.yeastgenome.org/locus/S000002410" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03446-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002410", "url": "https://www.yeastgenome.org/locus/S000002410" }, { "database": "iPTMnet", "id": "Q03446", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03446" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q03446-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002410", "url": "https://www.yeastgenome.org/locus/S000002410" }, { "database": "iPTMnet", "id": "Q03446", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03446" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03446-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002410", "url": "https://www.yeastgenome.org/locus/S000002410" }, { "database": "iPTMnet", "id": "Q03446", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03446" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03446-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Thr80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002410", "url": "https://www.yeastgenome.org/locus/S000002410" }, { "database": "iPTMnet", "id": "Q03446", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03446" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q03446-1" }, { "uniprot_canonical_ac": "Q03558-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03558", "url": "https://www.uniprot.org/uniprotkb/Q03558" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 400, "chemical_mass": 45011.0, "gene_names": "OYE2;OYE2", "protein_name": "NADPH dehydrogenase 2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q03558", "url": "https://www.uniprot.org/uniprotkb/Q03558" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q03558", "url": "https://www.uniprot.org/uniprotkb/Q03558" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q03558", "url": "https://www.uniprot.org/uniprotkb/Q03558" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q03558", "url": "https://www.uniprot.org/uniprotkb/Q03558" } ], "pmid": "" } ], "molecular_function": [ { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "Q03558", "url": "https://www.uniprot.org/uniprotkb/Q03558" } ], "pmid": "" }, { "name": "NADPH dehydrogenase activity", "id": "GO:0003959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003959", "evidence": [ { "database": "UniProtKB", "id": "Q03558", "url": "https://www.uniprot.org/uniprotkb/Q03558" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03558-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Tyr135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Thr163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Thr211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Thr294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Thr299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Tyr305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Ser315", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Thr343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03558", "url": "https://www.uniprot.org/uniprotkb/Q03558" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Thr374", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Ser379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03558", "url": "https://www.uniprot.org/uniprotkb/Q03558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Thr388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Thr38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03558-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001222", "url": "https://www.yeastgenome.org/locus/S000001222" }, { "database": "iPTMnet", "id": "Q03558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q03558-1" }, { "uniprot_canonical_ac": "Q03705-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 181, "chemical_mass": 20662.0, "gene_names": "CGI121;CGI121", "protein_name": "EKC/KEOPS complex subunit CGI121", "disease": [ { "disease_id": "DOID:0080247", "name": "Galloway-Mowat syndrome 5", "description": "A Galloway-Mowat syndrome that has_material_basis_in homozygous mutation in the TPRKB gene on chromosome 2p13.", "url": "https://disease-ontology.org/term/DOID:0080247", "evidence": [ { "id": "0080247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080247" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" }, { "name": "EKC/KEOPS complex", "id": "GO:0000408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000408", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" }, { "name": "maintenance of translational fidelity", "id": "GO:1990145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990145", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" }, { "name": "tRNA threonylcarbamoyladenosine modification", "id": "GO:0002949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002949", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" }, { "name": "telomere maintenance via recombination", "id": "GO:0000722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000722", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "Q03705", "url": "https://www.uniprot.org/uniprotkb/Q03705" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q03705-1" }, { "uniprot_canonical_ac": "Q03714-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 838, "chemical_mass": 96653.0, "gene_names": "USA1;USA1", "protein_name": "U1 SNP1-associating protein 1", "disease": [], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" } ], "pmid": "" } ], "biological_process": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" } ], "pmid": "" }, { "name": "positive regulation of protein autoubiquitination", "id": "GO:1902499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902499", "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03714-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Ser374", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q03714", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03714" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004491", "url": "https://www.yeastgenome.org/locus/S000004491" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03714-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Ser376", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q03714", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03714" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004491", "url": "https://www.yeastgenome.org/locus/S000004491" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03714-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Ser379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03714", "url": "https://www.uniprot.org/uniprotkb/Q03714" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q03714", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03714" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004491", "url": "https://www.yeastgenome.org/locus/S000004491" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03714-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Thr383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03714", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03714" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004491", "url": "https://www.yeastgenome.org/locus/S000004491" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03714-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Ser387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03714", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03714" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004491", "url": "https://www.yeastgenome.org/locus/S000004491" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03714-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Ser469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004491", "url": "https://www.yeastgenome.org/locus/S000004491" }, { "database": "iPTMnet", "id": "Q03714", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03714" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q03714-1" }, { "uniprot_canonical_ac": "Q03818-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 150, "chemical_mass": 17222.0, "gene_names": "ATG16;APG15;APG16;ATG16;CVT11;SAP18;YM8520.08C", "protein_name": "Autophagy protein 16", "disease": [], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "C-terminal protein lipidation", "id": "GO:0006501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006501", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "autophagosome organization", "id": "GO:1905037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905037", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "Atg12-Atg5-Atg16 complex", "id": "GO:0034274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034274", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "vacuole-isolation membrane contact site", "id": "GO:0120095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120095", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "phagophore", "id": "GO:0061908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061908", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03818-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004769", "url": "https://www.yeastgenome.org/locus/S000004769" }, { "database": "iPTMnet", "id": "Q03818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03818" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03818-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004769", "url": "https://www.yeastgenome.org/locus/S000004769" }, { "database": "iPTMnet", "id": "Q03818", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03818" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q03818-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Asp101", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Significantly reduces autophagic activity; when associated with A-102.", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" }, { "database": "PubMed", "id": "19889643", "url": "https://glygen.org/publication/PubMed/19889643" } ] } ] }, { "uniprot_canonical_ac": "Q03818-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Glu102", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Significantly reduces autophagic activity; when associated with A-101.", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" }, { "database": "PubMed", "id": "19889643", "url": "https://glygen.org/publication/PubMed/19889643" } ] } ] }, { "uniprot_canonical_ac": "Q03818-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ile104", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "A", "comment": "Significantly reduces autophagic activity; when associated with A-108 and A-112.", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" }, { "database": "PubMed", "id": "19889643", "url": "https://glygen.org/publication/PubMed/19889643" } ] } ] }, { "uniprot_canonical_ac": "Q03818-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ile108", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "A", "comment": "Significantly reduces autophagic activity; when associated with A-104 and A-112.", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" }, { "database": "PubMed", "id": "19889643", "url": "https://glygen.org/publication/PubMed/19889643" } ] } ] }, { "uniprot_canonical_ac": "Q03818-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Val112", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Significantly reduces autophagic activity; when associated with A-104 and A-108.", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" }, { "database": "PubMed", "id": "19889643", "url": "https://glygen.org/publication/PubMed/19889643" } ] } ] }, { "uniprot_canonical_ac": "Q03818-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Arg35", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs interaction with ATG5and autophagy.", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" }, { "database": "PubMed", "id": "17192262", "url": "https://glygen.org/publication/PubMed/17192262" } ] } ] }, { "uniprot_canonical_ac": "Q03818-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Phe46", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Impairs interaction with ATG5and autophagy.", "evidence": [ { "database": "UniProtKB", "id": "Q03818", "url": "https://www.uniprot.org/uniprotkb/Q03818" }, { "database": "PubMed", "id": "17192262", "url": "https://glygen.org/publication/PubMed/17192262" } ] } ] } ], "record_id": "Q03818-1" }, { "uniprot_canonical_ac": "Q03862-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03862", "url": "https://www.uniprot.org/uniprotkb/Q03862" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 593, "chemical_mass": 65213.0, "gene_names": "ARX1;ARX1;YD8557.10c", "protein_name": "Probable metalloprotease ARX1", "disease": [], "biological_process": [ { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "Q03862", "url": "https://www.uniprot.org/uniprotkb/Q03862" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q03862", "url": "https://www.uniprot.org/uniprotkb/Q03862" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q03862", "url": "https://www.uniprot.org/uniprotkb/Q03862" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q03862", "url": "https://www.uniprot.org/uniprotkb/Q03862" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q03862", "url": "https://www.uniprot.org/uniprotkb/Q03862" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q03862", "url": "https://www.uniprot.org/uniprotkb/Q03862" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "Q03862", "url": "https://www.uniprot.org/uniprotkb/Q03862" } ], "pmid": "" } ], "molecular_function": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "Q03862", "url": "https://www.uniprot.org/uniprotkb/Q03862" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q03862", "url": "https://www.uniprot.org/uniprotkb/Q03862" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03862-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Thr296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Thr336", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Thr339", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "342", "end_pos": "342", "site_lbl": "Ser342", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Tyr388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Ser435", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Ser481", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Ser495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "579", "end_pos": "579", "site_lbl": "Ser579", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "582", "end_pos": "582", "site_lbl": "Thr582", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "583", "end_pos": "583", "site_lbl": "Ser583", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03862-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002508", "url": "https://www.yeastgenome.org/locus/S000002508" }, { "database": "iPTMnet", "id": "Q03862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q03862-1" }, { "uniprot_canonical_ac": "Q03899-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03899", "url": "https://www.uniprot.org/uniprotkb/Q03899" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 556, "chemical_mass": 65243.0, "gene_names": "", "protein_name": "F-box protein YDR131C", "disease": [], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "Q03899", "url": "https://www.uniprot.org/uniprotkb/Q03899" } ], "pmid": "" } ], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q03899", "url": "https://www.uniprot.org/uniprotkb/Q03899" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "Q03899", "url": "https://www.uniprot.org/uniprotkb/Q03899" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q03899", "url": "https://www.uniprot.org/uniprotkb/Q03899" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q03899", "url": "https://www.uniprot.org/uniprotkb/Q03899" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q03899", "url": "https://www.uniprot.org/uniprotkb/Q03899" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q03899-1" }, { "uniprot_canonical_ac": "Q03957-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 528, "chemical_mass": 60501.0, "gene_names": "CTK1;CTK1", "protein_name": "CTD kinase subunit alpha", "disease": [ { "disease_id": "DOID:0112247", "name": "congenital heart defects, dysmorphic facial features, and intellectual developmental disorder", "description": "A syndrome characterized by congenital heart defects, dysmorphic facial features, and impaired intellectual developmental that has_material_basis_in heterozygous mutation in the CDK13 gene on chromosome 7p14.1.", "url": "https://disease-ontology.org/term/DOID:0112247", "evidence": [ { "id": "0112247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112247" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10286", "name": "prostate carcinoma", "description": "A prostate cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:10286", "evidence": [ { "id": "10286", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10286" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "RNA polymerase II CTD heptapeptide repeat kinase activity", "id": "GO:0008353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008353", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "cyclin/CDK positive transcription elongation factor complex", "id": "GO:0008024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008024", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "CTDK-1 complex", "id": "GO:0070692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070692", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "positive regulation of translational fidelity", "id": "GO:0045903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045903", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription, elongation", "id": "GO:0032786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032786", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03957-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" } ] } ] }, { "uniprot_canonical_ac": "Q03957-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Thr175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001622", "url": "https://www.yeastgenome.org/locus/S000001622" }, { "database": "iPTMnet", "id": "Q03957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03957" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q03957-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Ser252", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001622", "url": "https://www.yeastgenome.org/locus/S000001622" }, { "database": "iPTMnet", "id": "Q03957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03957" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03957-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03957" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000001622", "url": "https://www.yeastgenome.org/locus/S000001622" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03957-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03957" }, { "database": "PubMed", "id": "11751637", "url": "https://glygen.org/publication/PubMed/11751637" }, { "database": "PubMed", "id": "15870265", "url": "https://glygen.org/publication/PubMed/15870265" } ] } ] }, { "uniprot_canonical_ac": "Q03957-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Thr338", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" }, { "database": "PubMed", "id": "15870265", "url": "https://glygen.org/publication/PubMed/15870265" }, { "database": "iPTMnet", "id": "Q03957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03957" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001622", "url": "https://www.yeastgenome.org/locus/S000001622" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Cold-sensitive. Abolishes kinase activity. Delayed growth at early stationary phase. Shows no increase in CTDSer-2 phosphorylation in the transition from rapid growth to stationary phase. Has compromised transcriptional activation of two stationary-phase genes CTT1 and SPI1.", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" }, { "database": "PubMed", "id": "15870265", "url": "https://glygen.org/publication/PubMed/15870265" } ] } ] }, { "uniprot_canonical_ac": "Q03957-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Tyr47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001622", "url": "https://www.yeastgenome.org/locus/S000001622" }, { "database": "iPTMnet", "id": "Q03957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03957" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03957-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001622", "url": "https://www.yeastgenome.org/locus/S000001622" }, { "database": "iPTMnet", "id": "Q03957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03957" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q03957-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001622", "url": "https://www.yeastgenome.org/locus/S000001622" }, { "database": "iPTMnet", "id": "Q03957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03957" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q03957-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Thr82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q03957", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q03957" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001622", "url": "https://www.yeastgenome.org/locus/S000001622" } ] } ] }, { "uniprot_canonical_ac": "Q03957-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Asp324", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Cold-sensitive. Sensitive to hydroxyurea and UV irradiation. Interferes with ATP-binding.", "evidence": [ { "database": "UniProtKB", "id": "Q03957", "url": "https://www.uniprot.org/uniprotkb/Q03957" }, { "database": "PubMed", "id": "15870265", "url": "https://glygen.org/publication/PubMed/15870265" }, { "database": "PubMed", "id": "12684377", "url": "https://glygen.org/publication/PubMed/12684377" } ] } ] } ], "record_id": "Q03957-1" }, { "uniprot_canonical_ac": "Q04002-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1493, "chemical_mass": 171102.0, "gene_names": "SCC2;SCC2;YD9395.14", "protein_name": "Sister chromatid cohesion protein 2", "disease": [ { "disease_id": "DOID:0080505", "name": "Cornelia de Lange syndrome 1", "description": "A Cornelia de Lange syndrome characterized by facial dysmorphism, including low anterior hairline, arched eyebrows, synophrys, anteverted nares, maxillary prognathism, long philtrum, thin lips, and 'carp' mouth, in association with prenatal and postnatal growth retardation, impaired intellectual development, and, in many cases, upper limb anomalies that has_material_basis_in heterozygous mutation in the NIPBL gene, which encodes a component of the cohesin complex, on chromosome 5p13.", "url": "https://disease-ontology.org/term/DOID:0080505", "evidence": [ { "id": "0080505", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080505" } ], "weight": 0.0 }, { "disease_id": "DOID:11725", "name": "Cornelia de Lange syndrome", "description": "A syndrome that is characterized by slow growth before and after birth, intellectual disability that is usually severe to profound, skeletal abnormalities involving the arms and hands, and distinctive facial features.", "url": "https://disease-ontology.org/term/DOID:11725", "evidence": [ { "id": "11725", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11725" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "cohesin loader activity", "id": "GO:0061775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061775", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "SMC loading complex", "id": "GO:0032116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032116", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "Scc2-Scc4 cohesin loading complex", "id": "GO:0090694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090694", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "2-micrometer circle DNA", "id": "GO:0005729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005729", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "mitotic chromosome condensation", "id": "GO:0007076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007076", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "establishment of mitotic sister chromatid cohesion", "id": "GO:0034087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034087", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000972", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "establishment of protein localization to chromatin", "id": "GO:0071169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071169", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "replication-born double-strand break repair via sister chromatid exchange", "id": "GO:1990414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990414", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "rDNA chromatin condensation", "id": "GO:0070550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070550", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "chromatin looping", "id": "GO:0140588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140588", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" }, { "name": "tRNA gene clustering", "id": "GO:0070058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070058", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04002-1", "start_pos": "1179", "end_pos": "1179", "site_lbl": "Ser1179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "1182", "end_pos": "1182", "site_lbl": "Ser1182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "E", "comment": "In scc2-CE; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU); when associated with E-1185.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "1183", "end_pos": "1183", "site_lbl": "Ser1183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "1185", "end_pos": "1185", "site_lbl": "Ser1185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "E", "comment": "In scc2-CE; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU); when associated with E-1182.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "1228", "end_pos": "1228", "site_lbl": "Ser1228", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002588", "url": "https://www.yeastgenome.org/locus/S000002588" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "In scc2-8A; mimics unphosphorylated form and leads to novel phosphorylation sites at Ser-43, Ser-74, Ser-162, Ser-360, Ser-1179 and Ser-1183; when associated with A-67; A-157; A-163; A-231; A-236; A-305 and A-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "In scc2-8E; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-67; E-157; E-163; E-231; E-236; E-305 and E-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "1314", "end_pos": "1314", "site_lbl": "Ser1314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002588", "url": "https://www.yeastgenome.org/locus/S000002588" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "SGD", "id": "S000002588", "url": "https://www.yeastgenome.org/locus/S000002588" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "In scc2-8A; mimics unphosphorylated form and leads to novel phosphorylation sites at Ser-43, Ser-74, Ser-162, Ser-360, Ser-1179 and Ser-1183; when associated with A-67; A-127; A-163; A-231; A-236; A-305 and A-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "In scc2-8E; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-67; E-127; E-163; E-231; E-236; E-305 and E-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Ser162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Ser163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "In scc2-8A; mimics unphosphorylated form and leads to novel phosphorylation sites at Ser-43, Ser-74, Ser-162, Ser-360, Ser-1179 and Ser-1183; when associated with A-67; A-127; A-157; A-231; A-236; A-305 and A-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "In scc2-8E; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-67; E-127; E-157; E-231; E-236; E-305 and E-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Thr231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "In scc2-8A; mimics unphosphorylated form and leads to novel phosphorylation sites at Ser-43, Ser-74, Ser-162, Ser-360, Ser-1179 and Ser-1183; when associated with A-67; A-127; A-157; A-163; A-236; A-305 and A-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] }, { "sequence_org": "T", "sequence_mut": "E", "comment": "In scc2-8E; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-67; E-127; E-157; E-163; E-236; E-305 and E-320. In scc2-2NE; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-236; E-305 and E-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Thr236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "In scc2-8A; mimics unphosphorylated form and leads to novel phosphorylation sites at Ser-43, Ser-74, Ser-162, Ser-360, Ser-1179 and Ser-1183; when associated with A-67; A-127; A-157; A-163; A-231; A-305 and A-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] }, { "sequence_org": "T", "sequence_mut": "E", "comment": "In scc2-8E; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-67; E-127; E-157; E-163; E-231; E-305 and E-320. In scc2-2NE; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-231; E-305 and E-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Ser305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "In scc2-8A; mimics unphosphorylated form and leads to novel phosphorylation sites at Ser-43; S-74; S-162; S-360; S-1179 and Ser-1183; when associated with A-67; A-127; A-157; A-163; A-231; A-236 and A-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "In scc2-8E; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-67; E-127; E-157; E-163; E-231; E-236 and E-320. In scc2-2NE; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-231; E-236 and E-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Ser320", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "In scc2-8A; mimics unphosphorylated form and leads to novel phosphorylation sites at S-43; S-74; S-162; S-360; S-1179 and S-1183; when associated with A-67; A-127; A-157; A-163; A-231; A-236 and A-305.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "In scc2-8E; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-67; E-127; E-157; E-163; E-231; E-236 and E-305. In scc2-2NE; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-231; E-236 and E-305.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Thr360", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Thr67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "In scc2-8A; mimics unphosphorylated form and leads to novel phosphorylation sites at Ser-43, Ser-74, Ser-162, Ser-360, Ser-1179 and Ser-1183; when associated with A-127; A-157; A-163; A-231; A-236; A-305 and A-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] }, { "sequence_org": "T", "sequence_mut": "E", "comment": "In scc2-8E; mimics constitutive phosphorylation, retains normal SCC2-SCC4 interactions and chromatin association, but exhibits decreased viability, sensitivity to genotoxic agents methyl methanesulfonate (MMS) and hydroxyurea (HU), and decreased stability of the MCD1 cohesin subunit in mitotic cells; when associated with E-127; E-157; E-163; E-231; E-236; E-305 and E-320.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "735", "end_pos": "735", "site_lbl": "Ser735", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] }, { "uniprot_canonical_ac": "Q04002-1", "start_pos": "753", "end_pos": "753", "site_lbl": "Ser753", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" }, { "database": "iPTMnet", "id": "Q04002", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04002" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "E", "comment": "Mimics constitutive phosphorylation and causes inviability through protein instability.", "evidence": [ { "database": "UniProtKB", "id": "Q04002", "url": "https://www.uniprot.org/uniprotkb/Q04002" }, { "database": "PubMed", "id": "26354421", "url": "https://glygen.org/publication/PubMed/26354421" } ] } ] } ], "record_id": "Q04002-1" }, { "uniprot_canonical_ac": "Q04053-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 625, "chemical_mass": 70741.0, "gene_names": "SNX41;SNX41", "protein_name": "Sorting nexin-41", "disease": [], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" }, { "name": "cytoplasmic side of endosome membrane", "id": "GO:0010009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010009", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "Q04053", "url": "https://www.uniprot.org/uniprotkb/Q04053" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04053-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Tyr185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Thr201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Ser468", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Ser472", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Thr473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "499", "end_pos": "499", "site_lbl": "Ser499", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "501", "end_pos": "501", "site_lbl": "Ser501", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "502", "end_pos": "502", "site_lbl": "Ser502", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Ser503", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "505", "end_pos": "505", "site_lbl": "Ser505", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Ser506", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "508", "end_pos": "508", "site_lbl": "Ser508", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Ser526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04053-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Thr529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002833", "url": "https://www.yeastgenome.org/locus/S000002833" }, { "database": "iPTMnet", "id": "Q04053", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04053" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "Q04053-1" }, { "uniprot_canonical_ac": "Q04080-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04080", "url": "https://www.uniprot.org/uniprotkb/Q04080" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 534, "chemical_mass": 60814.0, "gene_names": "GPI17;D9461.20;GPI17", "protein_name": "GPI transamidase component GPI17", "disease": [ { "disease_id": "DOID:0070382", "name": "developmental and epileptic encephalopathy 95", "description": "A developmental and epileptic encephalopathy characterized by severely impaired global development, hypotonia, weakness, ataxia, coarse facial features, and intractable seizures that has_material_basis_in homozygous or compound heterozygous mutation in the PIGS gene on chromosome 17q11.", "url": "https://disease-ontology.org/term/DOID:0070382", "evidence": [ { "id": "0070382", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070382" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q04080", "url": "https://www.uniprot.org/uniprotkb/Q04080" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q04080", "url": "https://www.uniprot.org/uniprotkb/Q04080" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q04080", "url": "https://www.uniprot.org/uniprotkb/Q04080" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "Q04080", "url": "https://www.uniprot.org/uniprotkb/Q04080" } ], "pmid": "" }, { "name": "GPI-anchor transamidase complex", "id": "GO:0042765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042765", "evidence": [ { "database": "UniProtKB", "id": "Q04080", "url": "https://www.uniprot.org/uniprotkb/Q04080" } ], "pmid": "" } ], "biological_process": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "Q04080", "url": "https://www.uniprot.org/uniprotkb/Q04080" } ], "pmid": "" }, { "name": "attachment of GPI anchor to protein", "id": "GO:0016255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016255", "evidence": [ { "database": "UniProtKB", "id": "Q04080", "url": "https://www.uniprot.org/uniprotkb/Q04080" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "Q04080", "url": "https://www.uniprot.org/uniprotkb/Q04080" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04080-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Asn100", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 100, "start_aa": "Asn", "end_pos": 100, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn100", "evidence": [ { "id": "Q04080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04080#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q04080-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Asn170", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 170, "start_aa": "Asn", "end_pos": 170, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn170", "evidence": [ { "id": "Q04080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04080#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q04080-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Asn228", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G81315DD", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=9UB7&bu=0&command=select+.D:228;+center+selection;+zoom+selection" }, "start_pos": 228, "start_aa": "Asn", "end_pos": 228, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn228", "evidence": [ { "id": "9UB7", "database": "PDB", "url": "https://www.rcsb.org/structure/9UB7" }, { "id": "9UB7", "database": "PDB", "url": "https://www.rcsb.org/structure/9UB7" }, { "id": "9UB7|D|228", "database": "", "url": "" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 228, "start_aa": "Asn", "end_pos": 228, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn228", "evidence": [ { "id": "Q04080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04080#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q04080-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Asn247", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 247, "start_aa": "Asn", "end_pos": 247, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn247", "evidence": [ { "id": "Q04080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04080#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q04080-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Asn299", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 299, "start_aa": "Asn", "end_pos": 299, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn299", "evidence": [ { "id": "Q04080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04080#ptm_processing" } ] } ] } ], "record_id": "Q04080-1" }, { "uniprot_canonical_ac": "Q04149-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 632, "chemical_mass": 72309.0, "gene_names": "MUS81;D9509.6;MUS81;SLX3", "protein_name": "Crossover junction endonuclease MUS81", "disease": [ { "disease_id": "DOID:0050645", "name": "arterial tortuosity syndrome", "description": "A connective tissue disease that is characterized by elongation and generalized tortuosity of the major arteries including the aorta.", "url": "https://disease-ontology.org/term/DOID:0050645", "evidence": [ { "id": "0050645", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050645" } ], "weight": 0.0 }, { "disease_id": "DOID:14323", "name": "Marfan syndrome", "description": "A connective tissue disease that is characterized by tall stature, elongated extremities, mitral valve prolapse, aortic dilatation, aortic dissection, and subluxation of the lens.", "url": "https://disease-ontology.org/term/DOID:14323", "evidence": [ { "id": "14323", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14323" } ], "weight": 0.0 }, { "disease_id": "DOID:9675", "name": "pulmonary emphysema", "description": "A chronic obstructive pulmonary disease that is characterized by permanent enlargement of air spaces distal to the terminal bronchioles and the destruction of the alveolar walls.", "url": "https://disease-ontology.org/term/DOID:9675", "evidence": [ { "id": "9675", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9675" } ], "weight": 0.0 } ], "biological_process": [ { "name": "resolution of meiotic recombination intermediates", "id": "GO:0000712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000712", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "mitotic intra-S DNA damage checkpoint signaling", "id": "GO:0031573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031573", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "DNA topological change", "id": "GO:0006265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006265", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "DNA catabolic process", "id": "GO:0006308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006308", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "Holliday junction resolvase complex", "id": "GO:0048476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048476", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" }, { "name": "crossover junction DNA endonuclease activity", "id": "GO:0008821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008821", "evidence": [ { "database": "UniProtKB", "id": "Q04149", "url": "https://www.uniprot.org/uniprotkb/Q04149" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04149-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 306, "start_aa": "Ser", "end_pos": 306, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser306", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q04149", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q04149" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 307, "start_aa": "Ser", "end_pos": 307, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser307", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q04149", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q04149" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Ser240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Thr242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Ser247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Thr250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Thr254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ser273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Ser301", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04149-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Thr318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002794", "url": "https://www.yeastgenome.org/locus/S000002794" }, { "database": "iPTMnet", "id": "Q04149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04149" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "Q04149-1" }, { "uniprot_canonical_ac": "Q04217-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1267, "chemical_mass": 144955.0, "gene_names": "ECM16;DHR1;ECM16;YM9553.04", "protein_name": "Probable ATP-dependent RNA helicase DHR1", "disease": [ { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:14448", "name": "46,XY complete gonadal dysgenesis", "description": "A gonadal dysgenesis that is characterized by a normal 46,XY karyotype along with a progressive loss of germ cells on the developing gonads of an embryo.", "url": "https://disease-ontology.org/term/DOID:14448", "evidence": [ { "id": "14448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14448" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04217-1", "start_pos": "869", "end_pos": "869", "site_lbl": "Thr869", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 869, "start_aa": "Thr", "end_pos": 869, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr869", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "Q04217-1", "start_pos": "1205", "end_pos": "1205", "site_lbl": "Ser1205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004735", "url": "https://www.yeastgenome.org/locus/S000004735" }, { "database": "iPTMnet", "id": "Q04217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04217" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04217-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004735", "url": "https://www.yeastgenome.org/locus/S000004735" }, { "database": "iPTMnet", "id": "Q04217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04217" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04217-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Tyr176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04217" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004735", "url": "https://www.yeastgenome.org/locus/S000004735" } ] } ] }, { "uniprot_canonical_ac": "Q04217-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04217", "url": "https://www.uniprot.org/uniprotkb/Q04217" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q04217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04217" }, { "database": "SGD", "id": "S000004735", "url": "https://www.yeastgenome.org/locus/S000004735" } ] } ] }, { "uniprot_canonical_ac": "Q04217-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04217" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004735", "url": "https://www.yeastgenome.org/locus/S000004735" } ] } ] }, { "uniprot_canonical_ac": "Q04217-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04217" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004735", "url": "https://www.yeastgenome.org/locus/S000004735" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04217-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Ser223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004735", "url": "https://www.yeastgenome.org/locus/S000004735" }, { "database": "iPTMnet", "id": "Q04217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04217" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04217-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Ser299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04217" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q04217-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Ser302", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04217" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q04217-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Thr338", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004735", "url": "https://www.yeastgenome.org/locus/S000004735" }, { "database": "iPTMnet", "id": "Q04217", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04217" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q04217-1" }, { "uniprot_canonical_ac": "Q04272-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 221, "chemical_mass": 25638.0, "gene_names": "VPS20;ASI10;CHM6;VPL10;VPS20;VPT20;YM9582.02C", "protein_name": "Vacuolar protein sorting-associated protein 20", "disease": [], "cellular_component": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear membrane reassembly", "id": "GO:0031468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031468", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "peroxisome organization", "id": "GO:0007031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007031", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "vesicle budding from membrane", "id": "GO:0006900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006900", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "intralumenal vesicle formation", "id": "GO:0070676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070676", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04272-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04272" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004682", "url": "https://www.yeastgenome.org/locus/S000004682" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04272-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Thr185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004682", "url": "https://www.yeastgenome.org/locus/S000004682" }, { "database": "iPTMnet", "id": "Q04272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04272-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Thr207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004682", "url": "https://www.yeastgenome.org/locus/S000004682" }, { "database": "iPTMnet", "id": "Q04272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04272-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004682", "url": "https://www.yeastgenome.org/locus/S000004682" }, { "database": "iPTMnet", "id": "Q04272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04272" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04272-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Thr213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004682", "url": "https://www.yeastgenome.org/locus/S000004682" }, { "database": "iPTMnet", "id": "Q04272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04272" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04272-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04272" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] } ] }, { "uniprot_canonical_ac": "Q04272-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Gly2", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Loss of membrane association.", "evidence": [ { "database": "UniProtKB", "id": "Q04272", "url": "https://www.uniprot.org/uniprotkb/Q04272" }, { "database": "PubMed", "id": "12194857", "url": "https://glygen.org/publication/PubMed/12194857" } ] } ] } ], "record_id": "Q04272-1" }, { "uniprot_canonical_ac": "Q04431-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04431", "url": "https://www.uniprot.org/uniprotkb/Q04431" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 385, "chemical_mass": 44675.0, "gene_names": "KRE28;KRE28", "protein_name": "Outer kinetochore KNL1 complex subunit KRE28", "disease": [], "biological_process": [ { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "Q04431", "url": "https://www.uniprot.org/uniprotkb/Q04431" } ], "pmid": "" }, { "name": "homologous chromosome orientation in meiotic metaphase I", "id": "GO:0031619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031619", "evidence": [ { "database": "UniProtKB", "id": "Q04431", "url": "https://www.uniprot.org/uniprotkb/Q04431" } ], "pmid": "" }, { "name": "regulation of meiosis I spindle assembly checkpoint", "id": "GO:1905325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905325", "evidence": [ { "database": "UniProtKB", "id": "Q04431", "url": "https://www.uniprot.org/uniprotkb/Q04431" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q04431", "url": "https://www.uniprot.org/uniprotkb/Q04431" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q04431", "url": "https://www.uniprot.org/uniprotkb/Q04431" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q04431", "url": "https://www.uniprot.org/uniprotkb/Q04431" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "Q04431", "url": "https://www.uniprot.org/uniprotkb/Q04431" } ], "pmid": "" }, { "name": "Knl1/Spc105 complex", "id": "GO:0180019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180019", "evidence": [ { "database": "UniProtKB", "id": "Q04431", "url": "https://www.uniprot.org/uniprotkb/Q04431" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04431-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Thr340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04431", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04431" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q04431-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Thr40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04431", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04431" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002940", "url": "https://www.yeastgenome.org/locus/S000002940" } ] } ] }, { "uniprot_canonical_ac": "Q04431-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Thr45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04431", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04431" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002940", "url": "https://www.yeastgenome.org/locus/S000002940" } ] } ] }, { "uniprot_canonical_ac": "Q04431-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04431", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04431" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002940", "url": "https://www.yeastgenome.org/locus/S000002940" } ] } ] }, { "uniprot_canonical_ac": "Q04431-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002940", "url": "https://www.yeastgenome.org/locus/S000002940" }, { "database": "iPTMnet", "id": "Q04431", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04431" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q04431-1" }, { "uniprot_canonical_ac": "Q04491-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 297, "chemical_mass": 33043.0, "gene_names": "SEC13;ANU3;L8167.4;SEC13", "protein_name": "Protein transport protein SEC13", "disease": [ { "disease_id": "DOID:1508", "name": "candidiasis", "description": "An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons.", "url": "https://disease-ontology.org/term/DOID:1508", "evidence": [ { "id": "1508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1508" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "positive regulation of TOR signaling", "id": "GO:0032008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032008", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "positive regulation of ER to Golgi vesicle-mediated transport", "id": "GO:1902953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902953", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "positive regulation of protein exit from endoplasmic reticulum", "id": "GO:0070863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070863", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "COPII-coated vesicle budding", "id": "GO:0090114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090114", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "regulation of TORC1 signaling", "id": "GO:1903432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903432", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "protein exit from endoplasmic reticulum", "id": "GO:0032527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032527", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "nuclear pore localization", "id": "GO:0051664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051664", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore outer ring", "id": "GO:0031080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" }, { "name": "Seh1-associated complex", "id": "GO:0035859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035859", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04491-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Ser213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004198", "url": "https://www.yeastgenome.org/locus/S000004198" }, { "database": "iPTMnet", "id": "Q04491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04491" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04491-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004198", "url": "https://www.yeastgenome.org/locus/S000004198" }, { "database": "iPTMnet", "id": "Q04491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04491" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04491-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004198", "url": "https://www.yeastgenome.org/locus/S000004198" }, { "database": "iPTMnet", "id": "Q04491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04491" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "K", "comment": "Growth inhibited above 30 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" }, { "database": "PubMed", "id": "8432727", "url": "https://glygen.org/publication/PubMed/8432727" } ] } ] }, { "uniprot_canonical_ac": "Q04491-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Thr50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004198", "url": "https://www.yeastgenome.org/locus/S000004198" }, { "database": "iPTMnet", "id": "Q04491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04491" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04491-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Gly176", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "Leads to mislocalization of NPCs and overproliferation of the nuclear and ER membranes at 34 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" }, { "database": "PubMed", "id": "12215173", "url": "https://glygen.org/publication/PubMed/12215173" } ] } ] }, { "uniprot_canonical_ac": "Q04491-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Trp262", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "R", "comment": "Growth inhibited above 30 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" }, { "database": "PubMed", "id": "8432727", "url": "https://glygen.org/publication/PubMed/8432727" } ] } ] }, { "uniprot_canonical_ac": "Q04491-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Gly266", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Growth inhibited above 34 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "Q04491", "url": "https://www.uniprot.org/uniprotkb/Q04491" }, { "database": "PubMed", "id": "8432727", "url": "https://glygen.org/publication/PubMed/8432727" } ] } ] } ], "record_id": "Q04491-1" }, { "uniprot_canonical_ac": "Q04493-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 163, "chemical_mass": 18356.0, "gene_names": "GIM5;GIM5;PFD5", "protein_name": "Prefoldin subunit 5", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "pmid": "" }, { "name": "prefoldin complex", "id": "GO:0016272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016272", "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "pmid": "" }, { "name": "tubulin complex assembly", "id": "GO:0007021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007021", "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "pmid": "" }, { "name": "RNA polymerase II core complex assembly", "id": "GO:1990114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990114", "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "pmid": "" }, { "name": "RNA polymerase I assembly", "id": "GO:1990113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990113", "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "pmid": "" }, { "name": "RNA polymerase III assembly", "id": "GO:1990115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990115", "evidence": [ { "database": "UniProtKB", "id": "Q04493", "url": "https://www.uniprot.org/uniprotkb/Q04493" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04493-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004559", "url": "https://www.yeastgenome.org/locus/S000004559" }, { "database": "iPTMnet", "id": "Q04493", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04493" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q04493-1" }, { "uniprot_canonical_ac": "Q04511-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 668, "chemical_mass": 76860.0, "gene_names": "UFO1;UFO1", "protein_name": "Ubiquitin ligase complex F-box protein UFO1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" } ], "pmid": "" }, { "name": "cellular response to methylmercury", "id": "GO:0071406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071406", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04511-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Ser441", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004553", "url": "https://www.yeastgenome.org/locus/S000004553" }, { "database": "iPTMnet", "id": "Q04511", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04511" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "Q04511-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004553", "url": "https://www.yeastgenome.org/locus/S000004553" }, { "database": "iPTMnet", "id": "Q04511", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04511" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "Q04511-1", "start_pos": "453", "end_pos": "453", "site_lbl": "Ser453", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004553", "url": "https://www.yeastgenome.org/locus/S000004553" }, { "database": "iPTMnet", "id": "Q04511", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04511" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "Q04511-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Ser455", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004553", "url": "https://www.yeastgenome.org/locus/S000004553" }, { "database": "iPTMnet", "id": "Q04511", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04511" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "Q04511-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Ser495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004553", "url": "https://www.yeastgenome.org/locus/S000004553" }, { "database": "iPTMnet", "id": "Q04511", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04511" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04511-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Tyr504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004553", "url": "https://www.yeastgenome.org/locus/S000004553" }, { "database": "iPTMnet", "id": "Q04511", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04511" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04511-1", "start_pos": "511", "end_pos": "511", "site_lbl": "Ser511", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q04511", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04511" }, { "database": "SGD", "id": "S000004553", "url": "https://www.yeastgenome.org/locus/S000004553" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04511-1", "start_pos": "514", "end_pos": "514", "site_lbl": "Thr514", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04511", "url": "https://www.uniprot.org/uniprotkb/Q04511" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q04511", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04511" }, { "database": "SGD", "id": "S000004553", "url": "https://www.yeastgenome.org/locus/S000004553" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04511-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Ser529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004553", "url": "https://www.yeastgenome.org/locus/S000004553" }, { "database": "iPTMnet", "id": "Q04511", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04511" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q04511-1" }, { "uniprot_canonical_ac": "Q04549-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 284, "chemical_mass": 33018.0, "gene_names": "ARP10;ARP10;YD8557.15;YD9727.02", "protein_name": "Actin-like protein ARP10", "disease": [], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" }, { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" }, { "name": "dynactin complex", "id": "GO:0005869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005869", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "Q04549", "url": "https://www.uniprot.org/uniprotkb/Q04549" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q04549-1" }, { "uniprot_canonical_ac": "Q04601-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 652, "chemical_mass": 75256.0, "gene_names": "APC4;APC4", "protein_name": "Anaphase-promoting complex subunit 4", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "pmid": "" }, { "name": "regulation of meiotic cell cycle", "id": "GO:0051445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051445", "evidence": [ { "database": "UniProtKB", "id": "Q04601", "url": "https://www.uniprot.org/uniprotkb/Q04601" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q04601-1" }, { "uniprot_canonical_ac": "Q04632-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04632", "url": "https://www.uniprot.org/uniprotkb/Q04632" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 607, "chemical_mass": 69829.0, "gene_names": "COG8;COG8;DOR1", "protein_name": "Conserved oligomeric Golgi complex subunit 8", "disease": [ { "disease_id": "DOID:0070260", "name": "congenital disorder of glycosylation type IIh", "description": "A congenital disorder of glycosylation type II that has_material_basis_in a mutation of the COG8 gene on chromosome 16q22.1.", "url": "https://disease-ontology.org/term/DOID:0070260", "evidence": [ { "id": "0070260", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070260" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q04632", "url": "https://www.uniprot.org/uniprotkb/Q04632" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q04632", "url": "https://www.uniprot.org/uniprotkb/Q04632" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "Q04632", "url": "https://www.uniprot.org/uniprotkb/Q04632" } ], "pmid": "" } ], "biological_process": [ { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "Q04632", "url": "https://www.uniprot.org/uniprotkb/Q04632" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "Q04632", "url": "https://www.uniprot.org/uniprotkb/Q04632" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q04632", "url": "https://www.uniprot.org/uniprotkb/Q04632" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04632-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004536", "url": "https://www.yeastgenome.org/locus/S000004536" }, { "database": "iPTMnet", "id": "Q04632", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04632" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04632-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004536", "url": "https://www.yeastgenome.org/locus/S000004536" }, { "database": "iPTMnet", "id": "Q04632", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04632" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04632-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Ser397", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004536", "url": "https://www.yeastgenome.org/locus/S000004536" }, { "database": "iPTMnet", "id": "Q04632", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04632" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04632-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Thr406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004536", "url": "https://www.yeastgenome.org/locus/S000004536" }, { "database": "iPTMnet", "id": "Q04632", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04632" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04632-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Ser410", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q04632", "url": "https://www.uniprot.org/uniprotkb/Q04632" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q04632", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04632" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004536", "url": "https://www.yeastgenome.org/locus/S000004536" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04632-1", "start_pos": "433", "end_pos": "433", "site_lbl": "Thr433", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04632", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04632" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004536", "url": "https://www.yeastgenome.org/locus/S000004536" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04632-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Thr477", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004536", "url": "https://www.yeastgenome.org/locus/S000004536" }, { "database": "iPTMnet", "id": "Q04632", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04632" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q04632-1" }, { "uniprot_canonical_ac": "Q04651-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04651", "url": "https://www.uniprot.org/uniprotkb/Q04651" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 352, "chemical_mass": 40706.0, "gene_names": "ERV41;ERV41", "protein_name": "ER-derived vesicles protein ERV41", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q04651", "url": "https://www.uniprot.org/uniprotkb/Q04651" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q04651", "url": "https://www.uniprot.org/uniprotkb/Q04651" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "Q04651", "url": "https://www.uniprot.org/uniprotkb/Q04651" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q04651", "url": "https://www.uniprot.org/uniprotkb/Q04651" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "Q04651", "url": "https://www.uniprot.org/uniprotkb/Q04651" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q04651", "url": "https://www.uniprot.org/uniprotkb/Q04651" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q04651", "url": "https://www.uniprot.org/uniprotkb/Q04651" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "Q04651", "url": "https://www.uniprot.org/uniprotkb/Q04651" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q04651", "url": "https://www.uniprot.org/uniprotkb/Q04651" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q04651-1" }, { "uniprot_canonical_ac": "Q04693-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04693", "url": "https://www.uniprot.org/uniprotkb/Q04693" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1361, "chemical_mass": 153784.0, "gene_names": "RSE1;RSE1;SAP130;YM9827.03C", "protein_name": "Pre-mRNA-splicing factor RSE1", "disease": [], "molecular_function": [ { "name": "U2 snRNA binding", "id": "GO:0030620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030620", "evidence": [ { "database": "UniProtKB", "id": "Q04693", "url": "https://www.uniprot.org/uniprotkb/Q04693" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q04693", "url": "https://www.uniprot.org/uniprotkb/Q04693" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "Q04693", "url": "https://www.uniprot.org/uniprotkb/Q04693" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "Q04693", "url": "https://www.uniprot.org/uniprotkb/Q04693" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q04693", "url": "https://www.uniprot.org/uniprotkb/Q04693" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "Q04693", "url": "https://www.uniprot.org/uniprotkb/Q04693" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "Q04693", "url": "https://www.uniprot.org/uniprotkb/Q04693" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q04693-1", "start_pos": "931", "end_pos": "931", "site_lbl": "Ser931", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 931, "start_aa": "Ser", "end_pos": 931, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser931", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q04693", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q04693" } ] } ] }, { "uniprot_canonical_ac": "Q04693-1", "start_pos": "1278", "end_pos": "1278", "site_lbl": "Ser1278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004513", "url": "https://www.yeastgenome.org/locus/S000004513" }, { "database": "iPTMnet", "id": "Q04693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04693" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04693-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004513", "url": "https://www.yeastgenome.org/locus/S000004513" }, { "database": "iPTMnet", "id": "Q04693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04693" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04693-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Ser494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004513", "url": "https://www.yeastgenome.org/locus/S000004513" }, { "database": "iPTMnet", "id": "Q04693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04693" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04693-1", "start_pos": "496", "end_pos": "496", "site_lbl": "Ser496", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q04693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04693" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004513", "url": "https://www.yeastgenome.org/locus/S000004513" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q04693-1", "start_pos": "499", "end_pos": "499", "site_lbl": "Ser499", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004513", "url": "https://www.yeastgenome.org/locus/S000004513" }, { "database": "iPTMnet", "id": "Q04693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04693" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q04693-1", "start_pos": "966", "end_pos": "966", "site_lbl": "Ser966", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004513", "url": "https://www.yeastgenome.org/locus/S000004513" }, { "database": "iPTMnet", "id": "Q04693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04693" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q04693-1" }, { "uniprot_canonical_ac": "Q05016-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q05016", "url": "https://www.uniprot.org/uniprotkb/Q05016" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 267, "chemical_mass": 29158.0, "gene_names": "YM9959.08C", "protein_name": "NADP-dependent 3-hydroxy acid dehydrogenase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q05016", "url": "https://www.uniprot.org/uniprotkb/Q05016" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q05016", "url": "https://www.uniprot.org/uniprotkb/Q05016" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q05016", "url": "https://www.uniprot.org/uniprotkb/Q05016" } ], "pmid": "" }, { "name": "carbonyl reductase (NADPH) activity", "id": "GO:0004090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004090", "evidence": [ { "database": "UniProtKB", "id": "Q05016", "url": "https://www.uniprot.org/uniprotkb/Q05016" } ], "pmid": "" }, { "name": "serine 3-dehydrogenase activity", "id": "GO:0031132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031132", "evidence": [ { "database": "UniProtKB", "id": "Q05016", "url": "https://www.uniprot.org/uniprotkb/Q05016" } ], "pmid": "" }, { "name": "diacetyl reductase ((S)-acetoin forming) (NAD+) activity", "id": "GO:0052588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052588", "evidence": [ { "database": "UniProtKB", "id": "Q05016", "url": "https://www.uniprot.org/uniprotkb/Q05016" } ], "pmid": "" } ], "biological_process": [ { "name": "acetoin metabolic process", "id": "GO:0045149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045149", "evidence": [ { "database": "UniProtKB", "id": "Q05016", "url": "https://www.uniprot.org/uniprotkb/Q05016" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q05016-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" }, { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05016-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" }, { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05016-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Thr15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" }, { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05016-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Thr164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" }, { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05016-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" }, { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05016-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" }, { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05016-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" }, { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05016-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" }, { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05016-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Thr256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" } ] } ] }, { "uniprot_canonical_ac": "Q05016-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Ser260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05016", "url": "https://www.uniprot.org/uniprotkb/Q05016" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05016-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004839", "url": "https://www.yeastgenome.org/locus/S000004839" }, { "database": "iPTMnet", "id": "Q05016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q05016-1" }, { "uniprot_canonical_ac": "Q05027-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 157, "chemical_mass": 17315.0, "gene_names": "TAF9;TAF17;TAF9;YM9959.18", "protein_name": "SAGA complex/transcription factor TFIID complex subunit TAF9", "disease": [], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "SLIK (SAGA-like) complex", "id": "GO:0046695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046695", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "Q05027", "url": "https://www.uniprot.org/uniprotkb/Q05027" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q05027-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 13, "start_aa": "Ser", "end_pos": 13, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser13", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05027", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05027" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004849", "url": "https://www.yeastgenome.org/locus/S000004849" }, { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05027-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 16, "start_aa": "Ser", "end_pos": 16, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser16", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05027", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05027" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004849", "url": "https://www.yeastgenome.org/locus/S000004849" }, { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05027-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 18, "start_aa": "Ser", "end_pos": 18, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser18", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05027", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05027" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004849", "url": "https://www.yeastgenome.org/locus/S000004849" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05027-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 24, "start_aa": "Ser", "end_pos": 24, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser24", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05027", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05027" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004849", "url": "https://www.yeastgenome.org/locus/S000004849" }, { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05027-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004849", "url": "https://www.yeastgenome.org/locus/S000004849" }, { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05027-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004849", "url": "https://www.yeastgenome.org/locus/S000004849" }, { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05027-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Thr29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004849", "url": "https://www.yeastgenome.org/locus/S000004849" }, { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05027-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004849", "url": "https://www.yeastgenome.org/locus/S000004849" }, { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05027-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Ser83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004849", "url": "https://www.yeastgenome.org/locus/S000004849" }, { "database": "iPTMnet", "id": "Q05027", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05027" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q05027-1" }, { "uniprot_canonical_ac": "Q05050-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 843, "chemical_mass": 93345.0, "gene_names": "EIS1;EIS1;YM9973.04C", "protein_name": "Eisosome protein 1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" } ], "pmid": "" }, { "name": "eisosome", "id": "GO:0032126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032126", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" } ], "pmid": "" } ], "biological_process": [ { "name": "eisosome assembly", "id": "GO:0070941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070941", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q05050-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 168, "start_aa": "Ser", "end_pos": 168, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser168", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Ser170", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 170, "start_aa": "Ser", "end_pos": 170, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser170", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 171, "start_aa": "Ser", "end_pos": 171, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser171", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 175, "start_aa": "Ser", "end_pos": 175, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser175", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 177, "start_aa": "Ser", "end_pos": 177, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser177", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 179, "start_aa": "Ser", "end_pos": 179, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser179", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Thr181", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 181, "start_aa": "Thr", "end_pos": 181, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr181", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 182, "start_aa": "Ser", "end_pos": 182, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser182", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 184, "start_aa": "Ser", "end_pos": 184, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser184", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 185, "start_aa": "Ser", "end_pos": 185, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser185", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 188, "start_aa": "Ser", "end_pos": 188, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser188", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 191, "start_aa": "Ser", "end_pos": 191, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser191", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 193, "start_aa": "Ser", "end_pos": 193, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser193", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 196, "start_aa": "Ser", "end_pos": 196, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser196", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Ser752", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 752, "start_aa": "Ser", "end_pos": 752, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser752", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q05050", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q05050" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Thr100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Thr132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Thr135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Thr18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Ser249", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Ser397", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Ser401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Ser408", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Ser431", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "432", "end_pos": "432", "site_lbl": "Ser432", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Ser441", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "444", "end_pos": "444", "site_lbl": "Ser444", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "493", "end_pos": "493", "site_lbl": "Thr493", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Ser495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Thr50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "584", "end_pos": "584", "site_lbl": "Ser584", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Tyr586", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Ser613", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "616", "end_pos": "616", "site_lbl": "Ser616", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "649", "end_pos": "649", "site_lbl": "Ser649", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "656", "end_pos": "656", "site_lbl": "Ser656", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "681", "end_pos": "681", "site_lbl": "Ser681", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "700", "end_pos": "700", "site_lbl": "Thr700", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "701", "end_pos": "701", "site_lbl": "Ser701", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "704", "end_pos": "704", "site_lbl": "Tyr704", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "710", "end_pos": "710", "site_lbl": "Ser710", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "720", "end_pos": "720", "site_lbl": "Thr720", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "744", "end_pos": "744", "site_lbl": "Ser744", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "753", "end_pos": "753", "site_lbl": "Thr753", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "759", "end_pos": "759", "site_lbl": "Thr759", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "761", "end_pos": "761", "site_lbl": "Thr761", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "762", "end_pos": "762", "site_lbl": "Ser762", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "763", "end_pos": "763", "site_lbl": "Ser763", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "767", "end_pos": "767", "site_lbl": "Thr767", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "775", "end_pos": "775", "site_lbl": "Ser775", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "780", "end_pos": "780", "site_lbl": "Ser780", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "791", "end_pos": "791", "site_lbl": "Ser791", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "795", "end_pos": "795", "site_lbl": "Ser795", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "799", "end_pos": "799", "site_lbl": "Ser799", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "801", "end_pos": "801", "site_lbl": "Ser801", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "809", "end_pos": "809", "site_lbl": "Ser809", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "813", "end_pos": "813", "site_lbl": "Ser813", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "816", "end_pos": "816", "site_lbl": "Ser816", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "820", "end_pos": "820", "site_lbl": "Thr820", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "822", "end_pos": "822", "site_lbl": "Ser822", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "825", "end_pos": "825", "site_lbl": "Ser825", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "828", "end_pos": "828", "site_lbl": "Ser828", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "829", "end_pos": "829", "site_lbl": "Ser829", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "838", "end_pos": "838", "site_lbl": "Ser838", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004633", "url": "https://www.yeastgenome.org/locus/S000004633" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05050-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Ser88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05050", "url": "https://www.uniprot.org/uniprotkb/Q05050" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05050", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05050" } ] } ] } ], "record_id": "Q05050-1" }, { "uniprot_canonical_ac": "Q05636-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 305, "chemical_mass": 33962.0, "gene_names": "RRP45;D9954.1;RRP45", "protein_name": "Exosome complex component RRP45", "disease": [ { "disease_id": "DOID:0112323", "name": "pontocerebellar hypoplasia type 1D", "description": "A pontocerebellar hypoplasia type 1 characterized by severe hypotonia and motor neuronopathy detectable at birth or in infancy that has_material_basis_in homozygous or compound heterozygous mutation in the EXOSC9 gene on chromosome 4q27.", "url": "https://disease-ontology.org/term/DOID:0112323", "evidence": [ { "id": "0112323", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112323" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "U1 snRNA 3'-end processing", "id": "GO:0034473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034473", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "U5 snRNA 3'-end processing", "id": "GO:0034476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034476", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA 3'-UTR AU-rich region binding", "id": "GO:0035925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035925", "evidence": [ { "database": "UniProtKB", "id": "Q05636", "url": "https://www.uniprot.org/uniprotkb/Q05636" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q05636-1" }, { "uniprot_canonical_ac": "Q05785-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 613, "chemical_mass": 71807.0, "gene_names": "ENT2;ENT2", "protein_name": "Epsin-2", "disease": [ { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "K48-linked polyubiquitin modification-dependent protein binding", "id": "GO:0036435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036435", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" } ], "cellular_component": [ { "name": "clathrin vesicle coat", "id": "GO:0030125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030125", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" }, { "name": "actin cortical patch assembly", "id": "GO:0000147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000147", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q05785-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Thr165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Ser173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Tyr176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Thr190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Thr430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Ser434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Ser436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Tyr439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "444", "end_pos": "444", "site_lbl": "Thr444", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "448", "end_pos": "448", "site_lbl": "Thr448", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Thr450", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "454", "end_pos": "454", "site_lbl": "Thr454", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Thr458", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Thr468", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Thr470", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q05785", "url": "https://www.uniprot.org/uniprotkb/Q05785" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Thr472", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "476", "end_pos": "476", "site_lbl": "Ser476", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Thr479", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Tyr481", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "521", "end_pos": "521", "site_lbl": "Ser521", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05785-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Ser526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004196", "url": "https://www.yeastgenome.org/locus/S000004196" }, { "database": "iPTMnet", "id": "Q05785", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05785" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q05785-1" }, { "uniprot_canonical_ac": "Q05930-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 598, "chemical_mass": 70528.0, "gene_names": "MDM30;DSG1;MDM30", "protein_name": "Mitochondrial distribution and morphology protein 30", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "pmid": "" }, { "name": "regulation of mRNA export from nucleus", "id": "GO:0010793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010793", "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q05930", "url": "https://www.uniprot.org/uniprotkb/Q05930" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q05930-1" }, { "uniprot_canonical_ac": "Q05947-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q05947", "url": "https://www.uniprot.org/uniprotkb/Q05947" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 369, "chemical_mass": 42754.0, "gene_names": "UCC1;UCC1", "protein_name": "F-box protein UCC1", "disease": [], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q05947", "url": "https://www.uniprot.org/uniprotkb/Q05947" } ], "pmid": "" } ], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q05947", "url": "https://www.uniprot.org/uniprotkb/Q05947" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q05947", "url": "https://www.uniprot.org/uniprotkb/Q05947" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q05947", "url": "https://www.uniprot.org/uniprotkb/Q05947" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q05947-1" }, { "uniprot_canonical_ac": "Q05979-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 453, "chemical_mass": 51032.0, "gene_names": "BNA5;BNA5;L8083.14", "protein_name": "Kynureninase", "disease": [ { "disease_id": "DOID:0112257", "name": "hydroxykynureninuria", "description": "An amino acid metabolic disorder characterized by impaired tryptophan metabolism resulting in high urinary excretion of kynurenine, xanthurenic acid and 3-hydroxykynurenine that has_material_basis_in homozygous or compound heterozygous mutation in the KYNU gene on chromosome 2q22.2.", "url": "https://disease-ontology.org/term/DOID:0112257", "evidence": [ { "id": "0112257", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112257" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 } ], "biological_process": [ { "name": "L-kynurenine catabolic process", "id": "GO:0097053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097053", "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "pmid": "" }, { "name": "L-tryptophan catabolic process to kynurenine", "id": "GO:0019441", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019441", "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "pmid": "" }, { "name": "quinolinate biosynthetic process", "id": "GO:0019805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019805", "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "pmid": "" }, { "name": "anthranilate metabolic process", "id": "GO:0043420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043420", "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "pmid": "" }, { "name": "'de novo' NAD+ biosynthetic process from L-tryptophan", "id": "GO:0034354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034354", "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "pmid": "" }, { "name": "cytoophidium", "id": "GO:0097268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097268", "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "pmid": "" }, { "name": "kynureninase activity", "id": "GO:0030429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030429", "evidence": [ { "database": "UniProtKB", "id": "Q05979", "url": "https://www.uniprot.org/uniprotkb/Q05979" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q05979-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004221", "url": "https://www.yeastgenome.org/locus/S000004221" }, { "database": "iPTMnet", "id": "Q05979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05979" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q05979-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004221", "url": "https://www.yeastgenome.org/locus/S000004221" }, { "database": "iPTMnet", "id": "Q05979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05979" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q05979-1" }, { "uniprot_canonical_ac": "Q06096-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06096", "url": "https://www.uniprot.org/uniprotkb/Q06096" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 861, "chemical_mass": 98666.0, "gene_names": "COG4;COD1;COG4;P8283.16;SEC38;SGF1", "protein_name": "Conserved oligomeric Golgi complex subunit 4", "disease": [ { "disease_id": "DOID:0070262", "name": "congenital disorder of glycosylation type IIj", "description": "A congenital disorder of glycosylation type II that has_material_basis_in an autosomal recessive mutation of the COG4 gene on chromosome 16q22.1.", "url": "https://disease-ontology.org/term/DOID:0070262", "evidence": [ { "id": "0070262", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070262" } ], "weight": 0.0 }, { "disease_id": "DOID:0111673", "name": "Saul-Wilson syndrome", "description": "A bone development disease characterized by early developmental delay primarily involving speech, distinct facial features, short stature, brachydactyly, clubfoot deformities, cataracts, and microcephaly that has_material_basis_in heterozygous mutation in the COG4 gene on chromosome 16q22.1.", "url": "https://disease-ontology.org/term/DOID:0111673", "evidence": [ { "id": "0111673", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111673" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q06096", "url": "https://www.uniprot.org/uniprotkb/Q06096" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q06096", "url": "https://www.uniprot.org/uniprotkb/Q06096" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "Q06096", "url": "https://www.uniprot.org/uniprotkb/Q06096" } ], "pmid": "" } ], "biological_process": [ { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q06096", "url": "https://www.uniprot.org/uniprotkb/Q06096" } ], "pmid": "" }, { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "Q06096", "url": "https://www.uniprot.org/uniprotkb/Q06096" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "Q06096", "url": "https://www.uniprot.org/uniprotkb/Q06096" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q06096", "url": "https://www.uniprot.org/uniprotkb/Q06096" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "Q06096", "url": "https://www.uniprot.org/uniprotkb/Q06096" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06096-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Ser349", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06096" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006309", "url": "https://www.yeastgenome.org/locus/S000006309" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06096-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06096" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006309", "url": "https://www.yeastgenome.org/locus/S000006309" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06096-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Thr356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06096" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006309", "url": "https://www.yeastgenome.org/locus/S000006309" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06096-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Thr360", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006309", "url": "https://www.yeastgenome.org/locus/S000006309" }, { "database": "iPTMnet", "id": "Q06096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06096" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06096-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Tyr50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06096" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q06096-1", "start_pos": "556", "end_pos": "556", "site_lbl": "Ser556", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06096" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006309", "url": "https://www.yeastgenome.org/locus/S000006309" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06096-1", "start_pos": "563", "end_pos": "563", "site_lbl": "Ser563", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006309", "url": "https://www.yeastgenome.org/locus/S000006309" }, { "database": "iPTMnet", "id": "Q06096", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06096" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06096-1" }, { "uniprot_canonical_ac": "Q06102-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 208, "chemical_mass": 24553.0, "gene_names": "YTH1;YTH1", "protein_name": "mRNA 3'-end-processing protein YTH1", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" } ], "pmid": "" }, { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription, poly(A)-coupled", "id": "GO:0030846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030846", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06102-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006311", "url": "https://www.yeastgenome.org/locus/S000006311" }, { "database": "iPTMnet", "id": "Q06102", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06102" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06102-1", "start_pos": "142", "end_pos": "142", "site_lbl": "His142", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "N", "comment": "Temperature- and formamide-sensitive; impaired polyadenylation activity.", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" }, { "database": "PubMed", "id": "10899131", "url": "https://glygen.org/publication/PubMed/10899131" } ] } ] }, { "uniprot_canonical_ac": "Q06102-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Cys67", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Lethal.", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" }, { "database": "PubMed", "id": "10899131", "url": "https://glygen.org/publication/PubMed/10899131" } ] } ] }, { "uniprot_canonical_ac": "Q06102-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Trp70", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Temperature- and formamide-sensitive; abolishes cleavage and polyadenylation activity.", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" }, { "database": "PubMed", "id": "10899131", "url": "https://glygen.org/publication/PubMed/10899131" } ] } ] }, { "uniprot_canonical_ac": "Q06102-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Cys75", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Lethal.", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" }, { "database": "PubMed", "id": "10899131", "url": "https://glygen.org/publication/PubMed/10899131" } ] } ] }, { "uniprot_canonical_ac": "Q06102-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Asp79", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Temperature- and formamide-sensitive; impaired polyadenylation activity.", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" }, { "database": "PubMed", "id": "10899131", "url": "https://glygen.org/publication/PubMed/10899131" } ] } ] }, { "uniprot_canonical_ac": "Q06102-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Cys81", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Lethal.", "evidence": [ { "database": "UniProtKB", "id": "Q06102", "url": "https://www.uniprot.org/uniprotkb/Q06102" }, { "database": "PubMed", "id": "10899131", "url": "https://glygen.org/publication/PubMed/10899131" } ] } ] } ], "record_id": "Q06102-1" }, { "uniprot_canonical_ac": "Q06106-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 887, "chemical_mass": 101120.0, "gene_names": "MRD1;MRD1", "protein_name": "Multiple RNA-binding domain-containing protein 1", "disease": [], "biological_process": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" }, { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" }, { "name": "small-subunit processome assembly", "id": "GO:0034462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034462", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" }, { "name": "rRNA primary transcript binding", "id": "GO:0042134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042134", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06106-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Ser162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Tyr224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Ser248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Ser264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06106", "url": "https://www.uniprot.org/uniprotkb/Q06106" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Ser305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Tyr308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Ser315", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Thr332", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006316", "url": "https://www.yeastgenome.org/locus/S000006316" }, { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06106-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Thr620", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06106" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "Q06106-1" }, { "uniprot_canonical_ac": "Q06150-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06150", "url": "https://www.uniprot.org/uniprotkb/Q06150" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 570, "chemical_mass": 66344.0, "gene_names": "BOP2;BOP2", "protein_name": "Protein BOP2", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06150-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Thr379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06150" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004257", "url": "https://www.yeastgenome.org/locus/S000004257" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06150-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Ser381", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004257", "url": "https://www.yeastgenome.org/locus/S000004257" }, { "database": "iPTMnet", "id": "Q06150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06150" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06150-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Ser383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06150", "url": "https://www.uniprot.org/uniprotkb/Q06150" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06150", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06150" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004257", "url": "https://www.yeastgenome.org/locus/S000004257" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06150-1" }, { "uniprot_canonical_ac": "Q06159-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06159", "url": "https://www.uniprot.org/uniprotkb/Q06159" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 398, "chemical_mass": 46628.0, "gene_names": "ATG39;ATG39", "protein_name": "Autophagy-related protein 39", "disease": [], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q06159", "url": "https://www.uniprot.org/uniprotkb/Q06159" } ], "pmid": "" } ], "cellular_component": [ { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "Q06159", "url": "https://www.uniprot.org/uniprotkb/Q06159" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q06159", "url": "https://www.uniprot.org/uniprotkb/Q06159" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "Q06159", "url": "https://www.uniprot.org/uniprotkb/Q06159" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "Q06159", "url": "https://www.uniprot.org/uniprotkb/Q06159" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "Q06159", "url": "https://www.uniprot.org/uniprotkb/Q06159" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "Q06159", "url": "https://www.uniprot.org/uniprotkb/Q06159" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "Q06159", "url": "https://www.uniprot.org/uniprotkb/Q06159" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06159-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004303", "url": "https://www.yeastgenome.org/locus/S000004303" }, { "database": "iPTMnet", "id": "Q06159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06159" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06159-1" }, { "uniprot_canonical_ac": "Q06164-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1454, "chemical_mass": 167683.0, "gene_names": "MMS22;MMS22;SLM2", "protein_name": "E3 ubiquitin-protein ligase substrate receptor MMS22", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "pmid": "" }, { "name": "Cul8-RING ubiquitin ligase complex", "id": "GO:0035361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035361", "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "pmid": "" }, { "name": "recombinational repair", "id": "GO:0000725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000725", "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "pmid": "" }, { "name": "meiotic sister chromatid segregation", "id": "GO:0045144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045144", "evidence": [ { "database": "UniProtKB", "id": "Q06164", "url": "https://www.uniprot.org/uniprotkb/Q06164" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06164-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Ser169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004312", "url": "https://www.yeastgenome.org/locus/S000004312" }, { "database": "iPTMnet", "id": "Q06164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06164" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06164-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004312", "url": "https://www.yeastgenome.org/locus/S000004312" }, { "database": "iPTMnet", "id": "Q06164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06164" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06164-1" }, { "uniprot_canonical_ac": "Q06178-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 401, "chemical_mass": 45859.0, "gene_names": "NMA1;L8543.16;NMA1", "protein_name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1", "disease": [ { "disease_id": "DOID:0110005", "name": "Leber congenital amaurosis 9", "description": "A Leber congenital amaurosis that has_material_basis_in mutation in the NMNAT1 gene on chromosome 1p36.", "url": "https://disease-ontology.org/term/DOID:0110005", "evidence": [ { "id": "0110005", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110005" } ], "weight": 0.0 }, { "disease_id": "DOID:0112290", "name": "spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis", "description": "A syndrome characterized by early-onset retinal degeneration, sensorineural hearing loss, short stature, vertebral anomalies, epiphyseal dysplasia, and motor and intellectual delay that has_material_basis_in homozygous or compound heterozygous mutation in NMNAT1 on chromosome 1p36.22.", "url": "https://disease-ontology.org/term/DOID:0112290", "evidence": [ { "id": "0112290", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112290" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" } ], "pmid": "" }, { "name": "nicotinate-nucleotide adenylyltransferase activity", "id": "GO:0004515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004515", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" } ], "pmid": "" }, { "name": "nicotinamide-nucleotide adenylyltransferase activity", "id": "GO:0000309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000309", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" } ], "pmid": "" } ], "biological_process": [ { "name": "NAD+ biosynthetic process", "id": "GO:0009435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009435", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" } ], "pmid": "" }, { "name": "NAD+ biosynthetic process via the salvage pathway", "id": "GO:0034355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034355", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06178-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Tyr109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Ser111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Thr114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Thr115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06178-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06178", "url": "https://www.uniprot.org/uniprotkb/Q06178" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06178" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004320", "url": "https://www.yeastgenome.org/locus/S000004320" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06178-1" }, { "uniprot_canonical_ac": "Q06211-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1407, "chemical_mass": 161238.0, "gene_names": "MMS1;KIM3;MMS1;RTT108;SLM6", "protein_name": "E3 ubiquitin-protein ligase linker protein MMS1", "disease": [], "biological_process": [ { "name": "nonfunctional rRNA decay", "id": "GO:0070651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070651", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "pmid": "" }, { "name": "recombinational repair", "id": "GO:0000725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000725", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "pmid": "" }, { "name": "transposable element silencing", "id": "GO:0010526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010526", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "pmid": "" }, { "name": "Cul8-RING ubiquitin ligase complex", "id": "GO:0035361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035361", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06211-1", "start_pos": "1211", "end_pos": "1211", "site_lbl": "Ser1211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006368", "url": "https://www.yeastgenome.org/locus/S000006368" }, { "database": "iPTMnet", "id": "Q06211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06211-1", "start_pos": "1259", "end_pos": "1259", "site_lbl": "Ser1259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006368", "url": "https://www.yeastgenome.org/locus/S000006368" }, { "database": "iPTMnet", "id": "Q06211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06211-1", "start_pos": "1294", "end_pos": "1294", "site_lbl": "Thr1294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06211", "url": "https://www.uniprot.org/uniprotkb/Q06211" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q06211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006368", "url": "https://www.yeastgenome.org/locus/S000006368" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06211-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06211" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006368", "url": "https://www.yeastgenome.org/locus/S000006368" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06211-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006368", "url": "https://www.yeastgenome.org/locus/S000006368" }, { "database": "iPTMnet", "id": "Q06211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06211-1" }, { "uniprot_canonical_ac": "Q06263-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 330, "chemical_mass": 37316.0, "gene_names": "VTA1;VTA1", "protein_name": "Vacuolar protein sorting-associated protein VTA1", "disease": [], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" } ], "pmid": "" }, { "name": "ESCRT IV complex", "id": "GO:1990621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990621", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06263-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Thr173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Thr195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Thr240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Thr263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Ser278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06263" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004171", "url": "https://www.yeastgenome.org/locus/S000004171" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Trp122", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Abolishes interaction with VSP60 and DID2.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "18194651", "url": "https://glygen.org/publication/PubMed/18194651" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Lys152", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Abolishes interaction with VSP60 and DID2.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "18194651", "url": "https://glygen.org/publication/PubMed/18194651" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Lys299", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Abolishes interaction with VSP4.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "16505166", "url": "https://glygen.org/publication/PubMed/16505166" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Lys302", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Abolishes interaction with VSP4.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "16505166", "url": "https://glygen.org/publication/PubMed/16505166" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Tyr303", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes interaction with VSP4, no effect on dimerization.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "18194651", "url": "https://glygen.org/publication/PubMed/18194651" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Diminishes interaction with VSP4.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "16505166", "url": "https://glygen.org/publication/PubMed/16505166" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Tyr310", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes interaction with VSP4, no effect on dimerization.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "18194651", "url": "https://glygen.org/publication/PubMed/18194651" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "311", "end_pos": "311", "site_lbl": "Glu311", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Abolishes interaction with VSP4 and dimerization.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "18194651", "url": "https://glygen.org/publication/PubMed/18194651" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Asp312", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes interaction with VSP4 and dimerization.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "18194651", "url": "https://glygen.org/publication/PubMed/18194651" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Leu320", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "E", "comment": "Abolishes dimerization.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "18194651", "url": "https://glygen.org/publication/PubMed/18194651" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Lys322", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on interaction with VSP4.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "16505166", "url": "https://glygen.org/publication/PubMed/16505166" } ] } ] }, { "uniprot_canonical_ac": "Q06263-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Leu327", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "E", "comment": "Abolishes dimerization.", "evidence": [ { "database": "UniProtKB", "id": "Q06263", "url": "https://www.uniprot.org/uniprotkb/Q06263" }, { "database": "PubMed", "id": "18194651", "url": "https://glygen.org/publication/PubMed/18194651" } ] } ] } ], "record_id": "Q06263-1" }, { "uniprot_canonical_ac": "Q06337-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 982, "chemical_mass": 112502.0, "gene_names": "EAF1;EAF1;VID21", "protein_name": "Chromatin modification-related protein EAF1", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" } ], "pmid": "" }, { "name": "protein localization to nuclear inner membrane", "id": "GO:0036228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036228", "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06337-1", "start_pos": "831", "end_pos": "831", "site_lbl": "Ser831", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 831, "start_aa": "Ser", "end_pos": 831, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser831", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q06337", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q06337" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "836", "end_pos": "836", "site_lbl": "Ser836", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 836, "start_aa": "Ser", "end_pos": 836, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser836", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q06337", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q06337" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "837", "end_pos": "837", "site_lbl": "Ser837", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 837, "start_aa": "Ser", "end_pos": 837, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser837", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q06337", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q06337" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Ser417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "423", "end_pos": "423", "site_lbl": "Ser423", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Ser430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "433", "end_pos": "433", "site_lbl": "Ser433", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "437", "end_pos": "437", "site_lbl": "Ser437", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "440", "end_pos": "440", "site_lbl": "Ser440", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Ser489", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "588", "end_pos": "588", "site_lbl": "Ser588", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "591", "end_pos": "591", "site_lbl": "Ser591", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Ser613", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "616", "end_pos": "616", "site_lbl": "Ser616", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "739", "end_pos": "739", "site_lbl": "Ser739", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "841", "end_pos": "841", "site_lbl": "Ser841", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "849", "end_pos": "849", "site_lbl": "Ser849", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Thr91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "949", "end_pos": "949", "site_lbl": "Ser949", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Thr94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "951", "end_pos": "951", "site_lbl": "Ser951", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "954", "end_pos": "954", "site_lbl": "Ser954", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "969", "end_pos": "969", "site_lbl": "Ser969", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06337-1", "start_pos": "971", "end_pos": "971", "site_lbl": "Thr971", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06337", "url": "https://www.uniprot.org/uniprotkb/Q06337" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06337", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06337" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002767", "url": "https://www.yeastgenome.org/locus/S000002767" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] } ], "record_id": "Q06337-1" }, { "uniprot_canonical_ac": "Q06340-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 456, "chemical_mass": 52542.0, "gene_names": "ESC2;ESC2", "protein_name": "Protein ESC2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "positive regulation of endodeoxyribonuclease activity", "id": "GO:0032079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032079", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "positive regulation of protein sumoylation", "id": "GO:0033235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033235", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "mitotic intra-S DNA damage checkpoint signaling", "id": "GO:0031573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031573", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" } ], "molecular_function": [ { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "Y-form DNA binding", "id": "GO:0000403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000403", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "flap-structured DNA binding", "id": "GO:0070336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070336", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" }, { "name": "SUMO ligase regulator activity", "id": "GO:0180016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180016", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06340-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Ser128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Thr186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Thr192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Ser374", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "378", "end_pos": "378", "site_lbl": "Ser378", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Ser379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Thr67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Thr69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "PubMed", "id": "21725298", "url": "https://glygen.org/publication/PubMed/21725298" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Ser86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06340", "url": "https://www.uniprot.org/uniprotkb/Q06340" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" } ] } ] }, { "uniprot_canonical_ac": "Q06340-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Thr99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002771", "url": "https://www.yeastgenome.org/locus/S000002771" }, { "database": "iPTMnet", "id": "Q06340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06340" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06340-1" }, { "uniprot_canonical_ac": "Q06389-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06389", "url": "https://www.uniprot.org/uniprotkb/Q06389" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 190, "chemical_mass": 22011.0, "gene_names": "FRQ1;D9481.6;FRQ1;NCS1", "protein_name": "Calcium-binding protein NCS-1", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0090038", "name": "torsion dystonia 2", "description": "A dystonia that initially involves the distal limbs and later involves the neck, orofacial, and craniocervical regions, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the hippocalcin (HPCA) gene on chromosome 1p35.", "url": "https://disease-ontology.org/term/DOID:0090038", "evidence": [ { "id": "0090038", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090038" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q06389", "url": "https://www.uniprot.org/uniprotkb/Q06389" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q06389", "url": "https://www.uniprot.org/uniprotkb/Q06389" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q06389", "url": "https://www.uniprot.org/uniprotkb/Q06389" } ], "pmid": "" }, { "name": "cellular bud membrane", "id": "GO:0033101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033101", "evidence": [ { "database": "UniProtKB", "id": "Q06389", "url": "https://www.uniprot.org/uniprotkb/Q06389" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q06389", "url": "https://www.uniprot.org/uniprotkb/Q06389" } ], "pmid": "" }, { "name": "1-phosphatidylinositol 4-kinase activator activity", "id": "GO:0098744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098744", "evidence": [ { "database": "UniProtKB", "id": "Q06389", "url": "https://www.uniprot.org/uniprotkb/Q06389" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "Q06389", "url": "https://www.uniprot.org/uniprotkb/Q06389" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06389-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002781", "url": "https://www.yeastgenome.org/locus/S000002781" }, { "database": "iPTMnet", "id": "Q06389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06389" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06389-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Gly2", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Abolishes N-myristoylation.", "evidence": [ { "database": "UniProtKB", "id": "Q06389", "url": "https://www.uniprot.org/uniprotkb/Q06389" }, { "database": "PubMed", "id": "10559922", "url": "https://glygen.org/publication/PubMed/10559922" } ] } ] } ], "record_id": "Q06389-1" }, { "uniprot_canonical_ac": "Q06406-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 86, "chemical_mass": 9398.0, "gene_names": "LSM6;D9481.18;LSM6", "protein_name": "LSM complex subunit LSM6", "disease": [], "biological_process": [ { "name": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0000290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000290", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "sno(s)RNA-containing ribonucleoprotein complex", "id": "GO:0005732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005732", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "U6 snRNP", "id": "GO:0005688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005688", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" }, { "name": "Lsm1-7-Pat1 complex", "id": "GO:1990726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990726", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06406-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002786", "url": "https://www.yeastgenome.org/locus/S000002786" }, { "database": "iPTMnet", "id": "Q06406", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06406" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06406-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002786", "url": "https://www.yeastgenome.org/locus/S000002786" }, { "database": "iPTMnet", "id": "Q06406", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06406" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06406-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002786", "url": "https://www.yeastgenome.org/locus/S000002786" }, { "database": "iPTMnet", "id": "Q06406", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06406" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06406-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002786", "url": "https://www.yeastgenome.org/locus/S000002786" }, { "database": "iPTMnet", "id": "Q06406", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06406" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06406-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Arg74", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces affinity for poly-URNA ends.", "evidence": [ { "database": "UniProtKB", "id": "Q06406", "url": "https://www.uniprot.org/uniprotkb/Q06406" }, { "database": "PubMed", "id": "24240276", "url": "https://glygen.org/publication/PubMed/24240276" }, { "database": "PubMed", "id": "24513854", "url": "https://glygen.org/publication/PubMed/24513854" } ] } ] } ], "record_id": "Q06406-1" }, { "uniprot_canonical_ac": "Q06410-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 417, "chemical_mass": 48656.0, "gene_names": "ATG17;APG17;ATG17", "protein_name": "Autophagy-related protein 17", "disease": [], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" } ], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "positive regulation of autophagosome size", "id": "GO:0045772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045772", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "Atg1/ULK1 kinase complex", "id": "GO:1990316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990316", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" }, { "name": "vacuole-isolation membrane contact site", "id": "GO:0120095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120095", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06410-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Thr16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06410", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06410" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004415", "url": "https://www.yeastgenome.org/locus/S000004415" } ] } ] }, { "uniprot_canonical_ac": "Q06410-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Ser405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06410", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06410" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "Q06410-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Ser406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06410", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06410" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "Q06410-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Cys24", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "R", "comment": "Decreases affinity for ATG13.", "evidence": [ { "database": "UniProtKB", "id": "Q06410", "url": "https://www.uniprot.org/uniprotkb/Q06410" }, { "database": "PubMed", "id": "15743910", "url": "https://glygen.org/publication/PubMed/15743910" } ] } ] } ], "record_id": "Q06410-1" }, { "uniprot_canonical_ac": "Q06411-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 708, "chemical_mass": 83049.0, "gene_names": "SPP382;CCF8;NTR1;SPP382", "protein_name": "Pre-mRNA-splicing factor SPP382", "disease": [], "biological_process": [ { "name": "generation of catalytic spliceosome for first transesterification step", "id": "GO:0000349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000349", "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "pmid": "" }, { "name": "spliceosomal complex disassembly", "id": "GO:0000390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000390", "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "pmid": "" }, { "name": "negative regulation of double-strand break repair via nonhomologous end joining", "id": "GO:2001033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001033", "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "pmid": "" }, { "name": "U2-type post-mRNA release spliceosomal complex", "id": "GO:0071008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071008", "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q06411", "url": "https://www.uniprot.org/uniprotkb/Q06411" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06411-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004416", "url": "https://www.yeastgenome.org/locus/S000004416" }, { "database": "iPTMnet", "id": "Q06411", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06411-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004416", "url": "https://www.yeastgenome.org/locus/S000004416" }, { "database": "iPTMnet", "id": "Q06411", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06411" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06411-1", "start_pos": "611", "end_pos": "611", "site_lbl": "Ser611", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004416", "url": "https://www.yeastgenome.org/locus/S000004416" }, { "database": "iPTMnet", "id": "Q06411", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06411" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06411-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004416", "url": "https://www.yeastgenome.org/locus/S000004416" }, { "database": "iPTMnet", "id": "Q06411", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06411" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06411-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004416", "url": "https://www.yeastgenome.org/locus/S000004416" }, { "database": "iPTMnet", "id": "Q06411", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06411" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06411-1" }, { "uniprot_canonical_ac": "Q06412-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1307, "chemical_mass": 149113.0, "gene_names": "TUS1;SOP10;TUS1", "protein_name": "Rho1 guanine nucleotide exchange factor TUS1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" }, { "name": "regulation of cell wall organization or biogenesis", "id": "GO:1903338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903338", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" }, { "name": "positive regulation of mitotic actomyosin contractile ring assembly", "id": "GO:1903501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903501", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q06412", "url": "https://www.uniprot.org/uniprotkb/Q06412" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06412-1", "start_pos": "1163", "end_pos": "1163", "site_lbl": "Ser1163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "1168", "end_pos": "1168", "site_lbl": "Thr1168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Ser128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Ser131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Thr13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Ser170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Ser173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "789", "end_pos": "789", "site_lbl": "Ser789", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06412-1", "start_pos": "795", "end_pos": "795", "site_lbl": "Ser795", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004417", "url": "https://www.yeastgenome.org/locus/S000004417" }, { "database": "iPTMnet", "id": "Q06412", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06412" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06412-1" }, { "uniprot_canonical_ac": "Q06449-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06449", "url": "https://www.uniprot.org/uniprotkb/Q06449" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 215, "chemical_mass": 23539.0, "gene_names": "PIN3;LSB2;PIN3", "protein_name": "[PSI+] inducibility protein 3", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2526", "name": "prostate adenocarcinoma", "description": "A prostate carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2526", "evidence": [ { "id": "2526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2526" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06449", "url": "https://www.uniprot.org/uniprotkb/Q06449" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06449", "url": "https://www.uniprot.org/uniprotkb/Q06449" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "Q06449", "url": "https://www.uniprot.org/uniprotkb/Q06449" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034316", "evidence": [ { "database": "UniProtKB", "id": "Q06449", "url": "https://www.uniprot.org/uniprotkb/Q06449" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06449-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006358", "url": "https://www.yeastgenome.org/locus/S000006358" }, { "database": "iPTMnet", "id": "Q06449", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06449" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06449-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006358", "url": "https://www.yeastgenome.org/locus/S000006358" }, { "database": "iPTMnet", "id": "Q06449", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06449" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06449-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06449", "url": "https://www.uniprot.org/uniprotkb/Q06449" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06449", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06449" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000006358", "url": "https://www.yeastgenome.org/locus/S000006358" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06449-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06449", "url": "https://www.uniprot.org/uniprotkb/Q06449" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06449", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06449" }, { "database": "SGD", "id": "S000006358", "url": "https://www.yeastgenome.org/locus/S000006358" } ] } ] }, { "uniprot_canonical_ac": "Q06449-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Ser88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006358", "url": "https://www.yeastgenome.org/locus/S000006358" }, { "database": "iPTMnet", "id": "Q06449", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06449" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06449-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Lys80", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes formation of ubiquitinated protein forms.", "evidence": [ { "database": "UniProtKB", "id": "Q06449", "url": "https://www.uniprot.org/uniprotkb/Q06449" }, { "database": "PubMed", "id": "21777813", "url": "https://glygen.org/publication/PubMed/21777813" } ] } ] }, { "uniprot_canonical_ac": "Q06449-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Trp91", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "S", "comment": "Abolishes interaction with LAS17, but not with SUP35. Blocks colocalization with actin, aggregation, and prion-inducing ability.", "evidence": [ { "database": "UniProtKB", "id": "Q06449", "url": "https://www.uniprot.org/uniprotkb/Q06449" }, { "database": "PubMed", "id": "21777813", "url": "https://glygen.org/publication/PubMed/21777813" } ] } ] } ], "record_id": "Q06449-1" }, { "uniprot_canonical_ac": "Q06479-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06479", "url": "https://www.uniprot.org/uniprotkb/Q06479" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 807, "chemical_mass": 93123.0, "gene_names": "", "protein_name": "F-box protein YLR352W", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q06479", "url": "https://www.uniprot.org/uniprotkb/Q06479" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q06479", "url": "https://www.uniprot.org/uniprotkb/Q06479" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q06479", "url": "https://www.uniprot.org/uniprotkb/Q06479" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q06479", "url": "https://www.uniprot.org/uniprotkb/Q06479" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06479-1", "start_pos": "627", "end_pos": "627", "site_lbl": "Ser627", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06479" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004344", "url": "https://www.yeastgenome.org/locus/S000004344" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06479-1", "start_pos": "665", "end_pos": "665", "site_lbl": "Ser665", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004344", "url": "https://www.yeastgenome.org/locus/S000004344" }, { "database": "iPTMnet", "id": "Q06479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06479" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06479-1", "start_pos": "698", "end_pos": "698", "site_lbl": "Thr698", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004344", "url": "https://www.yeastgenome.org/locus/S000004344" }, { "database": "iPTMnet", "id": "Q06479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06479" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06479-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Ser713", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06479" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004344", "url": "https://www.yeastgenome.org/locus/S000004344" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06479-1" }, { "uniprot_canonical_ac": "Q06506-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 573, "chemical_mass": 65054.0, "gene_names": "RRP9;RRP9", "protein_name": "Ribosomal RNA-processing protein 9", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" }, { "name": "box C/D methylation guide snoRNP complex", "id": "GO:0031428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031428", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" } ], "molecular_function": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" }, { "name": "U3 snoRNA binding", "id": "GO:0034511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034511", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" } ], "biological_process": [ { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06506-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006341", "url": "https://www.yeastgenome.org/locus/S000006341" }, { "database": "iPTMnet", "id": "Q06506", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06506-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Thr29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06506", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q06506-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006341", "url": "https://www.yeastgenome.org/locus/S000006341" }, { "database": "iPTMnet", "id": "Q06506", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06506-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006341", "url": "https://www.yeastgenome.org/locus/S000006341" }, { "database": "iPTMnet", "id": "Q06506", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06506-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Thr455", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006341", "url": "https://www.yeastgenome.org/locus/S000006341" }, { "database": "iPTMnet", "id": "Q06506", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06506-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06506", "url": "https://www.uniprot.org/uniprotkb/Q06506" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006341", "url": "https://www.yeastgenome.org/locus/S000006341" }, { "database": "iPTMnet", "id": "Q06506", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506" } ] } ] }, { "uniprot_canonical_ac": "Q06506-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Tyr70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006341", "url": "https://www.yeastgenome.org/locus/S000006341" }, { "database": "iPTMnet", "id": "Q06506", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06506-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006341", "url": "https://www.yeastgenome.org/locus/S000006341" }, { "database": "iPTMnet", "id": "Q06506", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06506-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Thr83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006341", "url": "https://www.yeastgenome.org/locus/S000006341" }, { "database": "iPTMnet", "id": "Q06506", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "Q06506-1" }, { "uniprot_canonical_ac": "Q06512-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 552, "chemical_mass": 63637.0, "gene_names": "NOC4;NOC4;UTP19", "protein_name": "Nucleolar complex protein 4", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "Noc4p-Nop14p complex", "id": "GO:0030692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030692", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" } ], "biological_process": [ { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "Q06512", "url": "https://www.uniprot.org/uniprotkb/Q06512" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06512-1", "start_pos": "541", "end_pos": "541", "site_lbl": "Ser541", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006348", "url": "https://www.yeastgenome.org/locus/S000006348" }, { "database": "iPTMnet", "id": "Q06512", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06512" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06512-1" }, { "uniprot_canonical_ac": "Q06592-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06592", "url": "https://www.uniprot.org/uniprotkb/Q06592" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 156, "chemical_mass": 18334.0, "gene_names": "HPA2;HPA2;KAT10;P9677.12", "protein_name": "Histone acetyltransferase HPA2", "disease": [ { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 }, { "disease_id": "DOID:3324", "name": "mood disorder", "description": "A cognitive disorder that involves a disturbance in mood as the predominant underlying feature.", "url": "https://disease-ontology.org/term/DOID:3324", "evidence": [ { "id": "3324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3324" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein-lysine-acetyltransferase activity", "id": "GO:0061733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061733", "evidence": [ { "database": "UniProtKB", "id": "Q06592", "url": "https://www.uniprot.org/uniprotkb/Q06592" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q06592", "url": "https://www.uniprot.org/uniprotkb/Q06592" } ], "pmid": "" }, { "name": "aralkylamine N-acetyltransferase activity", "id": "GO:0004059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004059", "evidence": [ { "database": "UniProtKB", "id": "Q06592", "url": "https://www.uniprot.org/uniprotkb/Q06592" } ], "pmid": "" }, { "name": "N-acetyltransferase activity", "id": "GO:0008080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008080", "evidence": [ { "database": "UniProtKB", "id": "Q06592", "url": "https://www.uniprot.org/uniprotkb/Q06592" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06592", "url": "https://www.uniprot.org/uniprotkb/Q06592" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06592", "url": "https://www.uniprot.org/uniprotkb/Q06592" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q06592", "url": "https://www.uniprot.org/uniprotkb/Q06592" } ], "pmid": "" }, { "name": "protein acetylation", "id": "GO:0006473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006473", "evidence": [ { "database": "UniProtKB", "id": "Q06592", "url": "https://www.uniprot.org/uniprotkb/Q06592" } ], "pmid": "" }, { "name": "polyamine acetylation", "id": "GO:0032917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032917", "evidence": [ { "database": "UniProtKB", "id": "Q06592", "url": "https://www.uniprot.org/uniprotkb/Q06592" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06592-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006397", "url": "https://www.yeastgenome.org/locus/S000006397" }, { "database": "iPTMnet", "id": "Q06592", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06592" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06592-1" }, { "uniprot_canonical_ac": "Q06624-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06624", "url": "https://www.uniprot.org/uniprotkb/Q06624" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 347, "chemical_mass": 39273.0, "gene_names": "AOS1;AOS1;P9705.5;RHC31", "protein_name": "DNA damage tolerance protein RHC31", "disease": [ { "disease_id": "DOID:2531", "name": "hematologic cancer", "description": "An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.", "url": "https://disease-ontology.org/term/DOID:2531", "evidence": [ { "id": "2531", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2531" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "SUMO activating enzyme complex", "id": "GO:0031510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031510", "evidence": [ { "database": "UniProtKB", "id": "Q06624", "url": "https://www.uniprot.org/uniprotkb/Q06624" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06624", "url": "https://www.uniprot.org/uniprotkb/Q06624" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06624", "url": "https://www.uniprot.org/uniprotkb/Q06624" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q06624", "url": "https://www.uniprot.org/uniprotkb/Q06624" } ], "pmid": "" } ], "biological_process": [ { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "Q06624", "url": "https://www.uniprot.org/uniprotkb/Q06624" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q06624", "url": "https://www.uniprot.org/uniprotkb/Q06624" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like modifier activating enzyme activity", "id": "GO:0008641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008641", "evidence": [ { "database": "UniProtKB", "id": "Q06624", "url": "https://www.uniprot.org/uniprotkb/Q06624" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06624-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06624", "url": "https://www.uniprot.org/uniprotkb/Q06624" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06624" }, { "database": "SGD", "id": "S000006384", "url": "https://www.yeastgenome.org/locus/S000006384" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] } ], "record_id": "Q06624-1" }, { "uniprot_canonical_ac": "Q06628-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 738, "chemical_mass": 83281.0, "gene_names": "ATG13;APG13;ATG13", "protein_name": "Autophagy-related protein 13", "disease": [], "biological_process": [ { "name": "regulation of cellular localization", "id": "GO:0060341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060341", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "protein targeting to vacuole involved in autophagy", "id": "GO:0071211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071211", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "Cvt vesicle assembly", "id": "GO:0071255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071255", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "Atg1/ULK1 kinase complex", "id": "GO:1990316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990316", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "PAS complex", "id": "GO:0070772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070772", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "vacuole-isolation membrane contact site", "id": "GO:0120095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120095", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "protein kinase regulator activity", "id": "GO:0019887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019887", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" }, { "name": "armadillo repeat domain binding", "id": "GO:0070016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070016", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06628-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Ser280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19805182", "url": "https://glygen.org/publication/PubMed/19805182" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Decreases phosphorylation by PKA.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19805182", "url": "https://glygen.org/publication/PubMed/19805182" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Ser346", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19805182", "url": "https://glygen.org/publication/PubMed/19805182" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Ser348", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20383061", "url": "https://glygen.org/publication/PubMed/20383061" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to constitutive activation of autophagy; when associated with A-437; A-438; A-496; A-535; A-541; A-646 and A-649.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Thr351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Ser355", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Ser360", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Ser379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33536246", "url": "https://glygen.org/publication/PubMed/33536246" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Ser382", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "384", "end_pos": "384", "site_lbl": "Ser384", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "386", "end_pos": "386", "site_lbl": "Ser386", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Ser419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Ser424", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "427", "end_pos": "427", "site_lbl": "Ser427", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "428", "end_pos": "428", "site_lbl": "Ser428", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "32025038", "url": "https://glygen.org/publication/PubMed/32025038" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33536246", "url": "https://glygen.org/publication/PubMed/33536246" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Ser429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32025038", "url": "https://glygen.org/publication/PubMed/32025038" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33536246", "url": "https://glygen.org/publication/PubMed/33536246" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "437", "end_pos": "437", "site_lbl": "Ser437", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "20383061", "url": "https://glygen.org/publication/PubMed/20383061" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" }, { "database": "PubMed", "id": "19805182", "url": "https://glygen.org/publication/PubMed/19805182" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Decreases phosphorylation by PKA. Leads to constitutive activation of autophagy; when associated with A-348; A-438; A-496; A-535; A-541; A-646 and A-649.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" }, { "database": "PubMed", "id": "19805182", "url": "https://glygen.org/publication/PubMed/19805182" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "20383061", "url": "https://glygen.org/publication/PubMed/20383061" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to constitutive activation of autophagy; when associated with A-348; A-437; A-496; A-535; A-541; A-646 and A-649.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Thr441", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "454", "end_pos": "454", "site_lbl": "Ser454", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Ser461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Thr483", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ser484", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "496", "end_pos": "496", "site_lbl": "Ser496", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "20383061", "url": "https://glygen.org/publication/PubMed/20383061" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to constitutive activation of autophagy; when associated with A-348; A-437; A-438; A-535; A-541; A-646 and A-649.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Ser531", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "533", "end_pos": "533", "site_lbl": "Ser533", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "535", "end_pos": "535", "site_lbl": "Ser535", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "20383061", "url": "https://glygen.org/publication/PubMed/20383061" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to constitutive activation of autophagy; when associated with A-348; A-437; A-438; A-496; A-541; A-646 and A-649.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Ser539", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "541", "end_pos": "541", "site_lbl": "Ser541", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to constitutive activation of autophagy; when associated with A-348; A-437; A-438; A-496; A-535; A-646 and A-649.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "543", "end_pos": "543", "site_lbl": "Ser543", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "546", "end_pos": "546", "site_lbl": "Tyr546", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "548", "end_pos": "548", "site_lbl": "Ser548", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "554", "end_pos": "554", "site_lbl": "Ser554", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "560", "end_pos": "560", "site_lbl": "Ser560", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Ser570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "571", "end_pos": "571", "site_lbl": "Ser571", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "572", "end_pos": "572", "site_lbl": "Thr572", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "573", "end_pos": "573", "site_lbl": "Ser573", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Ser577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "581", "end_pos": "581", "site_lbl": "Ser581", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19805182", "url": "https://glygen.org/publication/PubMed/19805182" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Decreases phosphorylation by PKA.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19805182", "url": "https://glygen.org/publication/PubMed/19805182" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Ser585", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Ser604", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "637", "end_pos": "637", "site_lbl": "Ser637", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "644", "end_pos": "644", "site_lbl": "Ser644", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "20383061", "url": "https://glygen.org/publication/PubMed/20383061" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to constitutive activation of autophagy; when associated with A-348; A-437; A-438; A-496; A-535; A-541 and A-649.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "649", "end_pos": "649", "site_lbl": "Ser649", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "20383061", "url": "https://glygen.org/publication/PubMed/20383061" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to constitutive activation of autophagy; when associated with A-348; A-437; A-438; A-496; A-535; A-541, and A-646.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "19995911", "url": "https://glygen.org/publication/PubMed/19995911" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Ser652", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "654", "end_pos": "654", "site_lbl": "Ser654", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "656", "end_pos": "656", "site_lbl": "Ser656", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06628", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06628" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006389", "url": "https://www.yeastgenome.org/locus/S000006389" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Phe468", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Impairs binding to ATG1; when associated with A-469.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "22885598", "url": "https://glygen.org/publication/PubMed/22885598" } ] } ] }, { "uniprot_canonical_ac": "Q06628-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Val469", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Impairs binding to ATG1; when associated with A-468.", "evidence": [ { "database": "UniProtKB", "id": "Q06628", "url": "https://www.uniprot.org/uniprotkb/Q06628" }, { "database": "PubMed", "id": "22885598", "url": "https://glygen.org/publication/PubMed/22885598" } ] } ] } ], "record_id": "Q06628-1" }, { "uniprot_canonical_ac": "Q06639-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 885, "chemical_mass": 101720.0, "gene_names": "RSC3;D9740.13;RSC3", "protein_name": "Chromatin structure-remodeling complex protein RSC3", "disease": [], "biological_process": [ { "name": "regulation of nuclear cell cycle DNA replication", "id": "GO:0033262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033262", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" }, { "name": "RSC-type complex", "id": "GO:0016586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016586", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06639-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 119, "start_aa": "Ser", "end_pos": 119, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser119", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q06639", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q06639" } ] } ] }, { "uniprot_canonical_ac": "Q06639-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 120, "start_aa": "Ser", "end_pos": 120, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser120", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q06639", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q06639" } ] } ] }, { "uniprot_canonical_ac": "Q06639-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Ser236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q06639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06639" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002711", "url": "https://www.yeastgenome.org/locus/S000002711" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06639-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Thr241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002711", "url": "https://www.yeastgenome.org/locus/S000002711" }, { "database": "iPTMnet", "id": "Q06639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06639" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06639-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06639" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002711", "url": "https://www.yeastgenome.org/locus/S000002711" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06639-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06639" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002711", "url": "https://www.yeastgenome.org/locus/S000002711" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06639-1", "start_pos": "847", "end_pos": "847", "site_lbl": "Ser847", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002711", "url": "https://www.yeastgenome.org/locus/S000002711" }, { "database": "iPTMnet", "id": "Q06639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06639" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06639-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06639" }, { "database": "SGD", "id": "S000002711", "url": "https://www.yeastgenome.org/locus/S000002711" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06639-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Cys14", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "G", "comment": "Complete inactivation.", "evidence": [ { "database": "UniProtKB", "id": "Q06639", "url": "https://www.uniprot.org/uniprotkb/Q06639" }, { "database": "PubMed", "id": "11336698", "url": "https://glygen.org/publication/PubMed/11336698" } ] } ] } ], "record_id": "Q06639-1" }, { "uniprot_canonical_ac": "Q06640-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06640", "url": "https://www.uniprot.org/uniprotkb/Q06640" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 478, "chemical_mass": 54437.0, "gene_names": "", "protein_name": "F-box protein YDR306C", "disease": [], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q06640", "url": "https://www.uniprot.org/uniprotkb/Q06640" } ], "pmid": "" } ], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q06640", "url": "https://www.uniprot.org/uniprotkb/Q06640" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q06640", "url": "https://www.uniprot.org/uniprotkb/Q06640" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q06640", "url": "https://www.uniprot.org/uniprotkb/Q06640" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06640-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002714", "url": "https://www.yeastgenome.org/locus/S000002714" }, { "database": "iPTMnet", "id": "Q06640", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06640" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06640-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Ser81", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002714", "url": "https://www.yeastgenome.org/locus/S000002714" }, { "database": "iPTMnet", "id": "Q06640", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06640" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06640-1" }, { "uniprot_canonical_ac": "Q06679-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 776, "chemical_mass": 87801.0, "gene_names": "UTP4;UTP4", "protein_name": "U3 small nucleolar RNA-associated protein 4", "disease": [ { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "pmid": "" }, { "name": "t-UTP complex", "id": "GO:0034455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034455", "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "Q06679", "url": "https://www.uniprot.org/uniprotkb/Q06679" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06679-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Ser395", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06679", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06679" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] } ], "record_id": "Q06679-1" }, { "uniprot_canonical_ac": "Q06680-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1035, "chemical_mass": 117851.0, "gene_names": "YCG1;TIE1;YCG1;YCS5", "protein_name": "Condensin complex subunit 3", "disease": [], "biological_process": [ { "name": "meiotic chromosome separation", "id": "GO:0051307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051307", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "mitotic chromosome condensation", "id": "GO:0007076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007076", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "synaptonemal complex assembly", "id": "GO:0007130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007130", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "chromosome condensation", "id": "GO:0030261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030261", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "meiotic chromosome condensation", "id": "GO:0010032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010032", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "rDNA chromatin condensation", "id": "GO:0070550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070550", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "tRNA gene clustering", "id": "GO:0070058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070058", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "negative regulation of meiotic DNA double-strand break formation", "id": "GO:1903342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903342", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "condensed chromosome", "id": "GO:0000793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000793", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" }, { "name": "condensin complex", "id": "GO:0000796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000796", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06680-1", "start_pos": "1000", "end_pos": "1000", "site_lbl": "Thr1000", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "1001", "end_pos": "1001", "site_lbl": "Ser1001", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "1002", "end_pos": "1002", "site_lbl": "Thr1002", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "1008", "end_pos": "1008", "site_lbl": "Ser1008", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "1030", "end_pos": "1030", "site_lbl": "Ser1030", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Thr191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Ser406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "409", "end_pos": "409", "site_lbl": "Ser409", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "902", "end_pos": "902", "site_lbl": "Ser902", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "911", "end_pos": "911", "site_lbl": "Ser911", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "921", "end_pos": "921", "site_lbl": "Thr921", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "933", "end_pos": "933", "site_lbl": "Ser933", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "941", "end_pos": "941", "site_lbl": "Thr941", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "949", "end_pos": "949", "site_lbl": "Thr949", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "960", "end_pos": "960", "site_lbl": "Thr960", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "964", "end_pos": "964", "site_lbl": "Ser964", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "979", "end_pos": "979", "site_lbl": "Thr979", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "981", "end_pos": "981", "site_lbl": "Ser981", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q06680", "url": "https://www.uniprot.org/uniprotkb/Q06680" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "988", "end_pos": "988", "site_lbl": "Thr988", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "989", "end_pos": "989", "site_lbl": "Ser989", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q06680-1", "start_pos": "996", "end_pos": "996", "site_lbl": "Ser996", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q06680", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06680" }, { "database": "PubMed", "id": "19481522", "url": "https://glygen.org/publication/PubMed/19481522" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002733", "url": "https://www.yeastgenome.org/locus/S000002733" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q06680-1" }, { "uniprot_canonical_ac": "Q07084-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 712, "chemical_mass": 78529.0, "gene_names": "SSK1;SSK1", "protein_name": "Osmolarity two-component system protein SSK1", "disease": [], "biological_process": [ { "name": "regulation of p38MAPK cascade", "id": "GO:1900744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900744", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" } ], "pmid": "" }, { "name": "cellular hyperosmotic response", "id": "GO:0071474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071474", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" } ], "pmid": "" }, { "name": "cellular response to acidic pH", "id": "GO:0071468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071468", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" } ], "pmid": "" }, { "name": "osmosensory signaling via phosphorelay pathway", "id": "GO:0007234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007234", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" } ], "pmid": "" }, { "name": "mitogen-activated protein kinase kinase kinase binding", "id": "GO:0031435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031435", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" } ], "pmid": "" }, { "name": "phosphorelay response regulator activity", "id": "GO:0000156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000156", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q07084-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Thr183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Thr184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "25734609", "url": "https://glygen.org/publication/PubMed/25734609" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "25734609", "url": "https://glygen.org/publication/PubMed/25734609" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Ser327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Ser350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Ser351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Ser368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "380", "end_pos": "380", "site_lbl": "Ser380", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Ser460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ser484", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "587", "end_pos": "587", "site_lbl": "Ser587", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "589", "end_pos": "589", "site_lbl": "Ser589", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "673", "end_pos": "673", "site_lbl": "Ser673", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "681", "end_pos": "681", "site_lbl": "Ser681", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "690", "end_pos": "690", "site_lbl": "Thr690", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "691", "end_pos": "691", "site_lbl": "Ser691", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "693", "end_pos": "693", "site_lbl": "Thr693", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "695", "end_pos": "695", "site_lbl": "Thr695", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "697", "end_pos": "697", "site_lbl": "Ser697", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "703", "end_pos": "703", "site_lbl": "Ser703", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "706", "end_pos": "706", "site_lbl": "Ser706", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "708", "end_pos": "708", "site_lbl": "Thr708", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003996", "url": "https://www.yeastgenome.org/locus/S000003996" }, { "database": "iPTMnet", "id": "Q07084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07084" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "524", "end_pos": "524", "site_lbl": "Arg524", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Greatly diminished the binding affinity to YPD1.", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "31642125", "url": "https://glygen.org/publication/PubMed/31642125" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "525", "end_pos": "525", "site_lbl": "Lys525", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Greatly diminished the binding affinity to YPD1.", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "31642125", "url": "https://glygen.org/publication/PubMed/31642125" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "554", "end_pos": "554", "site_lbl": "Asp554", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Activates.", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "8183345", "url": "https://glygen.org/publication/PubMed/8183345" } ] } ] }, { "uniprot_canonical_ac": "Q07084-1", "start_pos": "638", "end_pos": "638", "site_lbl": "Trp638", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Leads to improved solubility and notable purification improvements, shows a moderate difference in binding affinity for YPD1, but does not affect levels of phosphoaccepting ability nor phosphorylated half-life.", "evidence": [ { "database": "UniProtKB", "id": "Q07084", "url": "https://www.uniprot.org/uniprotkb/Q07084" }, { "database": "PubMed", "id": "31642125", "url": "https://glygen.org/publication/PubMed/31642125" } ] } ] } ], "record_id": "Q07084-1" }, { "uniprot_canonical_ac": "Q07528-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 640, "chemical_mass": 72546.0, "gene_names": "ATG20;ATG20;CVT20;SNX42", "protein_name": "Autophagy-related protein 20", "disease": [], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" }, { "name": "cytoplasmic side of endosome membrane", "id": "GO:0010009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010009", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" }, { "name": "early endosome to Golgi transport", "id": "GO:0034498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034498", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q07528-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Tyr110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Ser132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Thr144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "342", "end_pos": "342", "site_lbl": "Ser342", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Ser361", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Ser363", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Thr365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002271", "url": "https://www.yeastgenome.org/locus/S000002271" }, { "database": "iPTMnet", "id": "Q07528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07528" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q07528-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Tyr193", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes the intracellular punctate localization and decreases the cytoplasm to vacuole transport.", "evidence": [ { "database": "UniProtKB", "id": "Q07528", "url": "https://www.uniprot.org/uniprotkb/Q07528" }, { "database": "PubMed", "id": "12048214", "url": "https://glygen.org/publication/PubMed/12048214" } ] } ] } ], "record_id": "Q07528-1" }, { "uniprot_canonical_ac": "Q07533-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 885, "chemical_mass": 100621.0, "gene_names": "CYK3;CYK3", "protein_name": "Cytokinesis protein 3", "disease": [ { "disease_id": "DOID:0080098", "name": "myofibrillar myopathy 7", "description": "A myofibrillar myopathy that has_material_basis_in homozygous mutation in the KY gene on chromosome 3q22.", "url": "https://disease-ontology.org/term/DOID:0080098", "evidence": [ { "id": "0080098", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080098" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" }, { "name": "HICS complex", "id": "GO:0044697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044697", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" }, { "name": "cellular bud neck contractile ring", "id": "GO:0000142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000142", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" }, { "name": "mitotic actomyosin contractile ring", "id": "GO:0110085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110085", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic cytokinetic process", "id": "GO:1902410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902410", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" }, { "name": "mitotic division septum assembly", "id": "GO:0140278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140278", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" }, { "name": "secondary cell septum biogenesis", "id": "GO:1990344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990344", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q07533-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Ser152", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ser159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Ser207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Tyr208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Ser209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Ser296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Ser322", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "323", "end_pos": "323", "site_lbl": "Ser323", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Ser347", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Ser348", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Ser350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Ser351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Thr372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "391", "end_pos": "391", "site_lbl": "Thr391", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07533", "url": "https://www.uniprot.org/uniprotkb/Q07533" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q07533-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002275", "url": "https://www.yeastgenome.org/locus/S000002275" }, { "database": "iPTMnet", "id": "Q07533", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07533" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "Q07533-1" }, { "uniprot_canonical_ac": "Q07540-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 174, "chemical_mass": 19490.0, "gene_names": "YFH1;YFH1", "protein_name": "Frataxin homolog, mitochondrial", "disease": [ { "disease_id": "DOID:0111218", "name": "Friedreich ataxia 1", "description": "A Friedreich ataxia that has_material_basis_in homozygous or compound heterozygous mutation in FXN on 9q21.1.", "url": "https://disease-ontology.org/term/DOID:0111218", "evidence": [ { "id": "0111218", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111218" } ], "weight": 0.0 }, { "disease_id": "DOID:12705", "name": "Friedreich ataxia", "description": "", "url": "https://disease-ontology.org/term/DOID:12705", "evidence": [ { "id": "12705", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12705" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:2351", "name": "iron metabolism disease", "description": "", "url": "https://disease-ontology.org/term/DOID:2351", "evidence": [ { "id": "2351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2351" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "response to iron(II) ion", "id": "GO:0010040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010040", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "heme biosynthetic process", "id": "GO:0006783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006783", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "mitochondrial electron transport, succinate to ubiquinone", "id": "GO:0006121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006121", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "ferroxidase activity", "id": "GO:0004322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004322", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "iron chaperone activity", "id": "GO:0034986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034986", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" }, { "name": "ferric iron binding", "id": "GO:0008199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008199", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q07540-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002278", "url": "https://www.yeastgenome.org/locus/S000002278" }, { "database": "iPTMnet", "id": "Q07540", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07540" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07540-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Glu103", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Impairs resistance to iron-catalyzed oxidative stress, no effect on Fe(2+) delivery and cell growth; when associated with A-93 and A-97.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "16371422", "url": "https://glygen.org/publication/PubMed/16371422" } ] } ] }, { "uniprot_canonical_ac": "Q07540-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Gln129", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Impairs cell growth and lowers aconitase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "19884169", "url": "https://glygen.org/publication/PubMed/19884169" } ] } ] }, { "uniprot_canonical_ac": "Q07540-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ile130", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "A", "comment": "Impairs cell growth and lowers aconitase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "19884169", "url": "https://glygen.org/publication/PubMed/19884169" } ] } ] }, { "uniprot_canonical_ac": "Q07540-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Trp131", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Impairs cell growth, lowers aconitase activity and strongly decreases interaction with ISU1.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "19884169", "url": "https://glygen.org/publication/PubMed/19884169" } ] }, { "sequence_org": "W", "sequence_mut": "F", "comment": "Lowers aconitase activity and no effexct on interaction with ISU1.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "19884169", "url": "https://glygen.org/publication/PubMed/19884169" } ] } ] }, { "uniprot_canonical_ac": "Q07540-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Arg141", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs cell growth and lowers aconitase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "19884169", "url": "https://glygen.org/publication/PubMed/19884169" } ] } ] }, { "uniprot_canonical_ac": "Q07540-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Tyr73", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Removes the iron-dependence for oligomerization and interaction with components of the core iron-sulfur cluster (ISC) assembly complex.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "26941001", "url": "https://glygen.org/publication/PubMed/26941001" } ] } ] }, { "uniprot_canonical_ac": "Q07540-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Asp79", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Nearly abolishes ferroxidase activity, slows down oligomerization, impairs resistance to iron-catalyzed oxidative stress, no effect on Fe(2+) delivery and cell growth; when associated with A-82.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "16371422", "url": "https://glygen.org/publication/PubMed/16371422" } ] } ] }, { "uniprot_canonical_ac": "Q07540-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Asp82", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Nearly abolishes ferroxidase activity, slows down oligomerization, impairs resistance to iron-catalyzed oxidative stress, no effect on Fe(2+) delivery and cell growth; when associated with A-79.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "16371422", "url": "https://glygen.org/publication/PubMed/16371422" } ] } ] }, { "uniprot_canonical_ac": "Q07540-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Glu93", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Impairs oligomerization and iron mineralization.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "16371422", "url": "https://glygen.org/publication/PubMed/16371422" } ] }, { "sequence_org": "E", "sequence_mut": "A", "comment": "Impairs resistance to iron-catalyzed oxidative stress, no effect on Fe(2+) delivery and cell growth; when associated with A-97 and A-103.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "16371422", "url": "https://glygen.org/publication/PubMed/16371422" } ] } ] }, { "uniprot_canonical_ac": "Q07540-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Asp97", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Impairs resistance to iron-catalyzed oxidative stress, no effect on Fe(2+) delivery and cell growth; when associated with A-93 and A-103.", "evidence": [ { "database": "UniProtKB", "id": "Q07540", "url": "https://www.uniprot.org/uniprotkb/Q07540" }, { "database": "PubMed", "id": "16371422", "url": "https://glygen.org/publication/PubMed/16371422" } ] } ] } ], "record_id": "Q07540-1" }, { "uniprot_canonical_ac": "Q07549-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07549", "url": "https://www.uniprot.org/uniprotkb/Q07549" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 140, "chemical_mass": 15673.0, "gene_names": "SNA4;SNA4", "protein_name": "Protein SNA4", "disease": [], "cellular_component": [ { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "Q07549", "url": "https://www.uniprot.org/uniprotkb/Q07549" } ], "pmid": "" }, { "name": "fungal-type vacuole lumen", "id": "GO:0000328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000328", "evidence": [ { "database": "UniProtKB", "id": "Q07549", "url": "https://www.uniprot.org/uniprotkb/Q07549" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q07549-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Thr116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002281", "url": "https://www.yeastgenome.org/locus/S000002281" }, { "database": "iPTMnet", "id": "Q07549", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07549" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07549-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07549", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07549" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002281", "url": "https://www.yeastgenome.org/locus/S000002281" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07549-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07549", "url": "https://www.uniprot.org/uniprotkb/Q07549" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "Q07549", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07549" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002281", "url": "https://www.yeastgenome.org/locus/S000002281" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07549-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Tyr138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07549", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07549" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] } ], "record_id": "Q07549-1" }, { "uniprot_canonical_ac": "Q07622-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07622", "url": "https://www.uniprot.org/uniprotkb/Q07622" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 623, "chemical_mass": 69371.0, "gene_names": "ACK1;ACK1;D1066", "protein_name": "Activator of C kinase protein 1", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q07622", "url": "https://www.uniprot.org/uniprotkb/Q07622" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of signal transduction", "id": "GO:0009967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009967", "evidence": [ { "database": "UniProtKB", "id": "Q07622", "url": "https://www.uniprot.org/uniprotkb/Q07622" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "Q07622", "url": "https://www.uniprot.org/uniprotkb/Q07622" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q07622-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Ser143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07622" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000002362", "url": "https://www.yeastgenome.org/locus/S000002362" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07622-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002362", "url": "https://www.yeastgenome.org/locus/S000002362" }, { "database": "iPTMnet", "id": "Q07622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07622" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07622-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002362", "url": "https://www.yeastgenome.org/locus/S000002362" }, { "database": "iPTMnet", "id": "Q07622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07622" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07622-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002362", "url": "https://www.yeastgenome.org/locus/S000002362" }, { "database": "iPTMnet", "id": "Q07622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07622" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "Q07622-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002362", "url": "https://www.yeastgenome.org/locus/S000002362" }, { "database": "iPTMnet", "id": "Q07622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07622" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07622-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002362", "url": "https://www.yeastgenome.org/locus/S000002362" }, { "database": "iPTMnet", "id": "Q07622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07622" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07622-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Thr314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07622" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "Q07622-1", "start_pos": "622", "end_pos": "622", "site_lbl": "Thr622", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q07622", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07622" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] } ], "record_id": "Q07622-1" }, { "uniprot_canonical_ac": "Q07688-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 167, "chemical_mass": 19169.0, "gene_names": "YPD1;D0790;YPD1", "protein_name": "Phosphorelay intermediate protein YPD1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphorelay signal transduction system", "id": "GO:0000160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000160", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" } ], "pmid": "" }, { "name": "osmosensory signaling via phosphorelay pathway", "id": "GO:0007234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007234", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" } ], "pmid": "" } ], "molecular_function": [ { "name": "transferase activity, transferring phosphorus-containing groups", "id": "GO:0016772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016772", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" } ], "pmid": "" }, { "name": "protein histidine kinase binding", "id": "GO:0043424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043424", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" } ], "pmid": "" }, { "name": "histidine phosphotransfer kinase activity", "id": "GO:0009927", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009927", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q07688-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002394", "url": "https://www.yeastgenome.org/locus/S000002394" }, { "database": "iPTMnet", "id": "Q07688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07688" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07688-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Thr57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002394", "url": "https://www.yeastgenome.org/locus/S000002394" }, { "database": "iPTMnet", "id": "Q07688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q07688-1", "start_pos": "64", "end_pos": "64", "site_lbl": "His64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" }, { "database": "PubMed", "id": "8808622", "url": "https://glygen.org/publication/PubMed/8808622" } ] } ], "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Q", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" }, { "database": "PubMed", "id": "8808622", "url": "https://glygen.org/publication/PubMed/8808622" } ] } ] }, { "uniprot_canonical_ac": "Q07688-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002394", "url": "https://www.yeastgenome.org/locus/S000002394" }, { "database": "iPTMnet", "id": "Q07688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07688" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07688-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002394", "url": "https://www.yeastgenome.org/locus/S000002394" }, { "database": "iPTMnet", "id": "Q07688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07688" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q07688-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Lys67", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Reduces binding of the 4-aspartylphosphate of SLN1.", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" }, { "database": "PubMed", "id": "15628880", "url": "https://glygen.org/publication/PubMed/15628880" } ] } ] }, { "uniprot_canonical_ac": "Q07688-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Gly68", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "Q", "comment": "Reduces phosphoryl transfer rate.", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" }, { "database": "PubMed", "id": "15628880", "url": "https://glygen.org/publication/PubMed/15628880" } ] } ] }, { "uniprot_canonical_ac": "Q07688-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Gly74", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "C", "comment": "In NH1; causes resistance to the antifungal antibiotic pradimicin.", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" }, { "database": "PubMed", "id": "15015733", "url": "https://glygen.org/publication/PubMed/15015733" } ] } ] }, { "uniprot_canonical_ac": "Q07688-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Gln86", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Reduces phosphoryl transfer rate.", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" }, { "database": "PubMed", "id": "15628880", "url": "https://glygen.org/publication/PubMed/15628880" } ] } ] }, { "uniprot_canonical_ac": "Q07688-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Arg90", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces phosphoryl transfer rate.", "evidence": [ { "database": "UniProtKB", "id": "Q07688", "url": "https://www.uniprot.org/uniprotkb/Q07688" }, { "database": "PubMed", "id": "15628880", "url": "https://glygen.org/publication/PubMed/15628880" } ] } ] } ], "record_id": "Q07688-1" }, { "uniprot_canonical_ac": "Q07748-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07748", "url": "https://www.uniprot.org/uniprotkb/Q07748" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 340, "chemical_mass": 38574.0, "gene_names": "THI13;THI13", "protein_name": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI13", "disease": [], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q07748", "url": "https://www.uniprot.org/uniprotkb/Q07748" } ], "pmid": "" }, { "name": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP", "id": "GO:0106344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106344", "evidence": [ { "database": "UniProtKB", "id": "Q07748", "url": "https://www.uniprot.org/uniprotkb/Q07748" } ], "pmid": "" } ], "biological_process": [ { "name": "thiamine diphosphate biosynthetic process", "id": "GO:0009229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009229", "evidence": [ { "database": "UniProtKB", "id": "Q07748", "url": "https://www.uniprot.org/uniprotkb/Q07748" } ], "pmid": "" }, { "name": "thiamine biosynthetic process", "id": "GO:0009228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009228", "evidence": [ { "database": "UniProtKB", "id": "Q07748", "url": "https://www.uniprot.org/uniprotkb/Q07748" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q07748-1" }, { "uniprot_canonical_ac": "Q07821-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 250, "chemical_mass": 27675.0, "gene_names": "ISA1;ISA1", "protein_name": "Iron-sulfur assembly protein 1", "disease": [ { "disease_id": "DOID:0080274", "name": "multiple mitochondrial dysfunctions syndrome 5", "description": "A multiple mitochondrial dysfunctions syndrome that is characterized by progressive neurologic deterioration beginning in early infancy, with affected individuals having no psychomotor development and early-onset seizures with neurologic decline and spasticity, and has_material_basis_in autosomal recessive inheritance of homozygous mutation in the iron-sulfur cluster assembly 1 gene on chromosome 9q21.", "url": "https://disease-ontology.org/term/DOID:0080274", "evidence": [ { "id": "0080274", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080274" } ], "weight": 0.0 } ], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "pmid": "" }, { "name": "[4Fe-4S] cluster assembly", "id": "GO:0044572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044572", "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "pmid": "" }, { "name": "biotin biosynthetic process", "id": "GO:0009102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009102", "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "pmid": "" } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q07821", "url": "https://www.uniprot.org/uniprotkb/Q07821" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q07821-1" }, { "uniprot_canonical_ac": "Q07879-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 167, "chemical_mass": 19760.0, "gene_names": "ATG10;APG10;ATG10", "protein_name": "Ubiquitin-like-conjugating enzyme ATG10", "disease": [], "biological_process": [ { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" } ], "pmid": "" }, { "name": "protein modification by small protein conjugation", "id": "GO:0032446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032446", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" } ], "pmid": "" } ], "cellular_component": [ { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" } ], "pmid": "" } ], "molecular_function": [ { "name": "Atg12 transferase activity", "id": "GO:0019777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019777", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q07879-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Cys133", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Complete loss of covalent binding to ATG12.", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" }, { "database": "PubMed", "id": "10508157", "url": "https://glygen.org/publication/PubMed/10508157" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Strong decrease of binding to ATG12. No more formation of ATG12-ATG5 conjugate. Defect in autophagy.", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" }, { "database": "PubMed", "id": "10508157", "url": "https://glygen.org/publication/PubMed/10508157" } ] } ] }, { "uniprot_canonical_ac": "Q07879-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Cys137", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on conjugating activity. Normal autophagic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" }, { "database": "PubMed", "id": "10508157", "url": "https://glygen.org/publication/PubMed/10508157" } ] } ] }, { "uniprot_canonical_ac": "Q07879-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Cys26", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on conjugating activity. Normal autophagic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q07879", "url": "https://www.uniprot.org/uniprotkb/Q07879" }, { "database": "PubMed", "id": "10508157", "url": "https://glygen.org/publication/PubMed/10508157" } ] } ] } ], "record_id": "Q07879-1" }, { "uniprot_canonical_ac": "Q07921-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 160, "chemical_mass": 18605.0, "gene_names": "TEN1;TEN1", "protein_name": "Telomere length regulation protein TEN1", "disease": [], "biological_process": [ { "name": "negative regulation of telomere maintenance", "id": "GO:0032205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032205", "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "pmid": "" }, { "name": "telomere capping", "id": "GO:0016233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016233", "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "pmid": "" }, { "name": "regulation of telomere maintenance via telomerase", "id": "GO:0032210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032210", "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "pmid": "" }, { "name": "telomere maintenance via telomerase", "id": "GO:0007004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007004", "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "pmid": "" } ], "molecular_function": [ { "name": "single-stranded telomeric DNA binding", "id": "GO:0043047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043047", "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "pmid": "" }, { "name": "translation elongation factor binding", "id": "GO:0061770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061770", "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "pmid": "" }, { "name": "transcription elongation factor activity", "id": "GO:0003711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003711", "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "pmid": "" } ], "cellular_component": [ { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "pmid": "" }, { "name": "CST complex", "id": "GO:1990879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990879", "evidence": [ { "database": "UniProtKB", "id": "Q07921", "url": "https://www.uniprot.org/uniprotkb/Q07921" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q07921-1" }, { "uniprot_canonical_ac": "Q07930-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07930", "url": "https://www.uniprot.org/uniprotkb/Q07930" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 204, "chemical_mass": 23654.0, "gene_names": "PML1;L1591;PML1", "protein_name": "Pre-mRNA leakage protein 1", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q07930", "url": "https://www.uniprot.org/uniprotkb/Q07930" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q07930", "url": "https://www.uniprot.org/uniprotkb/Q07930" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q07930", "url": "https://www.uniprot.org/uniprotkb/Q07930" } ], "pmid": "" }, { "name": "RES complex", "id": "GO:0070274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070274", "evidence": [ { "database": "UniProtKB", "id": "Q07930", "url": "https://www.uniprot.org/uniprotkb/Q07930" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "Q07930", "url": "https://www.uniprot.org/uniprotkb/Q07930" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q07930", "url": "https://www.uniprot.org/uniprotkb/Q07930" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "Q07930", "url": "https://www.uniprot.org/uniprotkb/Q07930" } ], "pmid": "" }, { "name": "maintenance of RNA location", "id": "GO:0051237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051237", "evidence": [ { "database": "UniProtKB", "id": "Q07930", "url": "https://www.uniprot.org/uniprotkb/Q07930" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q07930-1" }, { "uniprot_canonical_ac": "Q07980-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 695, "chemical_mass": 78248.0, "gene_names": "MLH2;MLH2", "protein_name": "DNA mismatch repair protein MLH2", "disease": [ { "disease_id": "DOID:0080745", "name": "polymyositis", "description": "A myositis that is characterized by muscle weakness affecting both sides of your body.", "url": "https://disease-ontology.org/term/DOID:0080745", "evidence": [ { "id": "0080745", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080745" } ], "weight": 0.0 }, { "disease_id": "DOID:10223", "name": "dermatomyositis", "description": "A myositis that results_in inflammation located_in muscle or located_in skin where a skin rash is often seen prior to the onset of muscle weakness. The disease may result from either a viral infection or an autoimmune reaction.", "url": "https://disease-ontology.org/term/DOID:10223", "evidence": [ { "id": "10223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10223" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:3883", "name": "Lynch syndrome", "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.", "url": "https://disease-ontology.org/term/DOID:3883", "evidence": [ { "id": "3883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3883" } ], "weight": 0.0 } ], "biological_process": [ { "name": "meiotic mismatch repair", "id": "GO:0000710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000710", "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "pmid": "" }, { "name": "mismatch repair", "id": "GO:0006298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006298", "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "pmid": "" }, { "name": "mismatched DNA binding", "id": "GO:0030983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030983", "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "pmid": "" }, { "name": "ATP-dependent DNA damage sensor activity", "id": "GO:0140664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140664", "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "pmid": "" }, { "name": "MutLalpha complex", "id": "GO:0032389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032389", "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "pmid": "" }, { "name": "MutLbeta complex", "id": "GO:0032390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032390", "evidence": [ { "database": "UniProtKB", "id": "Q07980", "url": "https://www.uniprot.org/uniprotkb/Q07980" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q07980-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Thr151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004025", "url": "https://www.yeastgenome.org/locus/S000004025" }, { "database": "iPTMnet", "id": "Q07980", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07980" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "Q07980-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004025", "url": "https://www.yeastgenome.org/locus/S000004025" }, { "database": "iPTMnet", "id": "Q07980", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q07980" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q07980-1" }, { "uniprot_canonical_ac": "Q08162-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1001, "chemical_mass": 113707.0, "gene_names": "DIS3;DIS3;MTR17;O2197;RRP44", "protein_name": "Exosome complex exonuclease DIS3", "disease": [ { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "nonfunctional rRNA decay", "id": "GO:0070651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070651", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent CUT catabolic process", "id": "GO:0071039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071039", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "nuclear mRNA surveillance of mRNA 3'-end processing", "id": "GO:0071031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071031", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "regulatory ncRNA 3'-end processing", "id": "GO:0043628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043628", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08162-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Ser240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005381", "url": "https://www.yeastgenome.org/locus/S000005381" }, { "database": "iPTMnet", "id": "Q08162", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08162" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005381", "url": "https://www.yeastgenome.org/locus/S000005381" }, { "database": "iPTMnet", "id": "Q08162", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08162" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Ser336", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005381", "url": "https://www.yeastgenome.org/locus/S000005381" }, { "database": "iPTMnet", "id": "Q08162", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08162" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005381", "url": "https://www.yeastgenome.org/locus/S000005381" }, { "database": "iPTMnet", "id": "Q08162", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08162" }, { "database": "PubMed", "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "698", "end_pos": "698", "site_lbl": "Ser698", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005381", "url": "https://www.yeastgenome.org/locus/S000005381" }, { "database": "iPTMnet", "id": "Q08162", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08162" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005381", "url": "https://www.yeastgenome.org/locus/S000005381" }, { "database": "iPTMnet", "id": "Q08162", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08162" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Asp171", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes endoribonucleolytic activity; no effect on growth. No growth; when associated with N-551.", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" }, { "database": "PubMed", "id": "19060898", "url": "https://glygen.org/publication/PubMed/19060898" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Asp198", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes endoribonucleolytic activity; no effect on growth. No growth; when associated with N-551.", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" }, { "database": "PubMed", "id": "19060898", "url": "https://glygen.org/publication/PubMed/19060898" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Cys47", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Slow growth; when associated with S-52 and S-55.", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" }, { "database": "PubMed", "id": "19060898", "url": "https://glygen.org/publication/PubMed/19060898" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Cys52", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Slow growth; when associated with S-47 and S-55.", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" }, { "database": "PubMed", "id": "19060898", "url": "https://glygen.org/publication/PubMed/19060898" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Asp551", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Exoribonucleolytic activity abolished. Accumulation of partially processed 5.8S rRNA and partially degraded 5' ETS. No growth; when associated with A-171. No growth; when associated with A-198.", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" }, { "database": "PubMed", "id": "17173052", "url": "https://glygen.org/publication/PubMed/17173052" }, { "database": "PubMed", "id": "18374646", "url": "https://glygen.org/publication/PubMed/18374646" }, { "database": "PubMed", "id": "19060898", "url": "https://glygen.org/publication/PubMed/19060898" } ] } ] }, { "uniprot_canonical_ac": "Q08162-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Cys55", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Slow growth; when associated with S-47 and S-52.", "evidence": [ { "database": "UniProtKB", "id": "Q08162", "url": "https://www.uniprot.org/uniprotkb/Q08162" }, { "database": "PubMed", "id": "19060898", "url": "https://glygen.org/publication/PubMed/19060898" } ] } ] } ], "record_id": "Q08162-1" }, { "uniprot_canonical_ac": "Q08204-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1093, "chemical_mass": 126037.0, "gene_names": "SMC5;SMC5", "protein_name": "Structural maintenance of chromosomes protein 5", "disease": [ { "disease_id": "DOID:0080688", "name": "mosaic variegated aneuploidy syndrome", "description": "A syndrome that is characterized by cell mosaicism where at least one-quarter of cells have an abnormal number of chromosomes.", "url": "https://disease-ontology.org/term/DOID:0080688", "evidence": [ { "id": "0080688", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080688" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of telomere maintenance", "id": "GO:0032204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032204", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "chromosome separation", "id": "GO:0051304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051304", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "recombinational repair", "id": "GO:0000725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000725", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "resolution of DNA recombination intermediates", "id": "GO:0071139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071139", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "chromatin looping", "id": "GO:0140588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140588", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" }, { "name": "Smc5-Smc6 complex", "id": "GO:0030915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030915", "evidence": [ { "database": "UniProtKB", "id": "Q08204", "url": "https://www.uniprot.org/uniprotkb/Q08204" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08204-1", "start_pos": "1091", "end_pos": "1091", "site_lbl": "Ser1091", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005394", "url": "https://www.yeastgenome.org/locus/S000005394" }, { "database": "iPTMnet", "id": "Q08204", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08204" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08204-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005394", "url": "https://www.yeastgenome.org/locus/S000005394" }, { "database": "iPTMnet", "id": "Q08204", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08204" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q08204-1" }, { "uniprot_canonical_ac": "Q08214-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 380, "chemical_mass": 43844.0, "gene_names": "NTG2;NTG2;SCR2", "protein_name": "Endonuclease III homolog 2", "disease": [ { "disease_id": "DOID:0080411", "name": "familial adenomatous polyposis 3", "description": "A familial adenomatous polyposis that has_material_basis_in homozygous or compound heterozygous mutation in the NTHL1 gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0080411", "evidence": [ { "id": "0080411", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080411" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" }, { "name": "class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0140078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140078", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" }, { "name": "oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity", "id": "GO:0000703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000703", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" } ], "biological_process": [ { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" }, { "name": "base-excision repair, AP site formation", "id": "GO:0006285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006285", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08214-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes interaction with MLH1.", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" }, { "database": "PubMed", "id": "12042306", "url": "https://glygen.org/publication/PubMed/12042306" } ] } ] }, { "uniprot_canonical_ac": "Q08214-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Tyr26", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes interaction with MLH1.", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" }, { "database": "PubMed", "id": "12042306", "url": "https://glygen.org/publication/PubMed/12042306" } ] } ] }, { "uniprot_canonical_ac": "Q08214-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Phe27", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Abolishes interaction with MLH1.", "evidence": [ { "database": "UniProtKB", "id": "Q08214", "url": "https://www.uniprot.org/uniprotkb/Q08214" }, { "database": "PubMed", "id": "12042306", "url": "https://glygen.org/publication/PubMed/12042306" } ] } ] } ], "record_id": "Q08214-1" }, { "uniprot_canonical_ac": "Q08278-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 222, "chemical_mass": 25585.0, "gene_names": "MED7;MED7", "protein_name": "Mediator of RNA polymerase II transcription subunit 7", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "Q08278", "url": "https://www.uniprot.org/uniprotkb/Q08278" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08278-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Thr212", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005495", "url": "https://www.yeastgenome.org/locus/S000005495" }, { "database": "iPTMnet", "id": "Q08278", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08278" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08278-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005495", "url": "https://www.yeastgenome.org/locus/S000005495" }, { "database": "iPTMnet", "id": "Q08278", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08278" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08278-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08278", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08278" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005495", "url": "https://www.yeastgenome.org/locus/S000005495" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08278-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005495", "url": "https://www.yeastgenome.org/locus/S000005495" }, { "database": "iPTMnet", "id": "Q08278", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08278" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q08278-1" }, { "uniprot_canonical_ac": "Q08285-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 240, "chemical_mass": 26556.0, "gene_names": "RRP40;MTR14;RRP40", "protein_name": "Exosome complex component RRP40", "disease": [ { "disease_id": "DOID:0060266", "name": "pontocerebellar hypoplasia type 1B", "description": "A severe pontocerebellar hypoplasia that is characterized by hypotonia, progressive microcephaly and developmental delay, has_material_basis_in autosomal recessive inheritance of mutation in the EXOSC3 gene.", "url": "https://disease-ontology.org/term/DOID:0060266", "evidence": [ { "id": "0060266", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060266" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" } ], "biological_process": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "CUT catabolic process", "id": "GO:0071034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071034", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" }, { "name": "poly(A)-dependent snoRNA 3'-end processing", "id": "GO:0071051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071051", "evidence": [ { "database": "UniProtKB", "id": "Q08285", "url": "https://www.uniprot.org/uniprotkb/Q08285" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08285-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Thr16", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005502", "url": "https://www.yeastgenome.org/locus/S000005502" }, { "database": "iPTMnet", "id": "Q08285", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08285" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "Q08285-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Thr17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005502", "url": "https://www.yeastgenome.org/locus/S000005502" }, { "database": "iPTMnet", "id": "Q08285", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08285" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q08285-1" }, { "uniprot_canonical_ac": "Q08457-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08457", "url": "https://www.uniprot.org/uniprotkb/Q08457" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 257, "chemical_mass": 29557.0, "gene_names": "SLD7;SLD7;YOR29-11", "protein_name": "Mitochondrial morphogenesis protein SLD7", "disease": [], "biological_process": [ { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "Q08457", "url": "https://www.uniprot.org/uniprotkb/Q08457" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "Q08457", "url": "https://www.uniprot.org/uniprotkb/Q08457" } ], "pmid": "" } ], "cellular_component": [ { "name": "DNA replication preinitiation complex", "id": "GO:0031261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031261", "evidence": [ { "database": "UniProtKB", "id": "Q08457", "url": "https://www.uniprot.org/uniprotkb/Q08457" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "Q08457", "url": "https://www.uniprot.org/uniprotkb/Q08457" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08457", "url": "https://www.uniprot.org/uniprotkb/Q08457" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q08457", "url": "https://www.uniprot.org/uniprotkb/Q08457" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08457", "url": "https://www.uniprot.org/uniprotkb/Q08457" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q08457", "url": "https://www.uniprot.org/uniprotkb/Q08457" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q08457", "url": "https://www.uniprot.org/uniprotkb/Q08457" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q08457-1" }, { "uniprot_canonical_ac": "Q08683-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 685, "chemical_mass": 79275.0, "gene_names": "APC5;APC5;RMC1", "protein_name": "Anaphase-promoting complex subunit 5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "pmid": "" }, { "name": "positive regulation of mitotic metaphase/anaphase transition", "id": "GO:0045842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045842", "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "pmid": "" }, { "name": "regulation of meiotic cell cycle", "id": "GO:0051445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051445", "evidence": [ { "database": "UniProtKB", "id": "Q08683", "url": "https://www.uniprot.org/uniprotkb/Q08683" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q08683-1" }, { "uniprot_canonical_ac": "Q08685-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 445, "chemical_mass": 50226.0, "gene_names": "CLP1;CLP1", "protein_name": "mRNA cleavage and polyadenylation factor CLP1", "disease": [ { "disease_id": "DOID:0060264", "name": "pontocerebellar hypoplasia", "description": "A neurodegenerative disease that is characterized by underdevelopment of the pons and cerebellum.", "url": "https://disease-ontology.org/term/DOID:0060264", "evidence": [ { "id": "0060264", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060264" } ], "weight": 0.0 }, { "disease_id": "DOID:0060279", "name": "pontocerebellar hypoplasia type 10", "description": "A pontocerebellar hypoplasia that is characterized by severe developmental delays, progressive microcephaly, spasticity and seizure, has_material_basis_in autosomal recessive inheritance of mutation in the CLP1 gene.", "url": "https://disease-ontology.org/term/DOID:0060279", "evidence": [ { "id": "0060279", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060279" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" } ], "pmid": "" }, { "name": "polynucleotide 5'-hydroxyl-kinase activity", "id": "GO:0051731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051731", "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" } ], "pmid": "" }, { "name": "mRNA cleavage factor complex", "id": "GO:0005849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005849", "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0006388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006388", "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08685-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005776", "url": "https://www.yeastgenome.org/locus/S000005776" }, { "database": "iPTMnet", "id": "Q08685", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08685" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08685-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005776", "url": "https://www.yeastgenome.org/locus/S000005776" }, { "database": "iPTMnet", "id": "Q08685", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08685" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08685-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Lys136", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Completely abolishes interaction with PCF11. No effect on growth; when associated with A-137.", "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" }, { "database": "PubMed", "id": "22216186", "url": "https://glygen.org/publication/PubMed/22216186" } ] } ] }, { "uniprot_canonical_ac": "Q08685-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Thr137", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Completely abolishes interaction with PCF11. No effect on growth; when associated with A-136.", "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" }, { "database": "PubMed", "id": "22216186", "url": "https://glygen.org/publication/PubMed/22216186" } ] } ] }, { "uniprot_canonical_ac": "Q08685-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Asp161", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Compromises interaction with PCF11. No effect on growth.", "evidence": [ { "database": "UniProtKB", "id": "Q08685", "url": "https://www.uniprot.org/uniprotkb/Q08685" }, { "database": "PubMed", "id": "22216186", "url": "https://glygen.org/publication/PubMed/22216186" }, { "database": "PubMed", "id": "18648070", "url": "https://glygen.org/publication/PubMed/18648070" } ] } ] } ], "record_id": "Q08685-1" }, { "uniprot_canonical_ac": "Q08723-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 338, "chemical_mass": 38313.0, "gene_names": "RPN8;O5360;RPN8", "protein_name": "26S proteasome regulatory subunit RPN8", "disease": [ { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "proteasome storage granule", "id": "GO:0034515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034515", "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" } ], "pmid": "" }, { "name": "proteasome regulatory particle, lid subcomplex", "id": "GO:0008541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008541", "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" } ], "pmid": "" } ], "molecular_function": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08723-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Thr241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "311", "end_pos": "311", "site_lbl": "Ser311", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Ser317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Ser321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Thr327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q08723", "url": "https://www.uniprot.org/uniprotkb/Q08723" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08723-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Thr45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08723", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08723" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000005787", "url": "https://www.yeastgenome.org/locus/S000005787" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q08723-1" }, { "uniprot_canonical_ac": "Q08817-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08817", "url": "https://www.uniprot.org/uniprotkb/Q08817" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 791, "chemical_mass": 87326.0, "gene_names": "SOG2;SOG2", "protein_name": "Leucine-rich repeat-containing protein SOG2", "disease": [], "biological_process": [ { "name": "septum digestion after cytokinesis", "id": "GO:0000920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000920", "evidence": [ { "database": "UniProtKB", "id": "Q08817", "url": "https://www.uniprot.org/uniprotkb/Q08817" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q08817", "url": "https://www.uniprot.org/uniprotkb/Q08817" } ], "pmid": "" }, { "name": "budding cell apical bud growth", "id": "GO:0007118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007118", "evidence": [ { "database": "UniProtKB", "id": "Q08817", "url": "https://www.uniprot.org/uniprotkb/Q08817" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08817", "url": "https://www.uniprot.org/uniprotkb/Q08817" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "Q08817", "url": "https://www.uniprot.org/uniprotkb/Q08817" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "Q08817", "url": "https://www.uniprot.org/uniprotkb/Q08817" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "Q08817", "url": "https://www.uniprot.org/uniprotkb/Q08817" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08817-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Ser469", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 469, "start_aa": "Ser", "end_pos": 469, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser469", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005880", "url": "https://www.yeastgenome.org/locus/S000005880" }, { "database": "iPTMnet", "id": "Q08817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08817" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Ser470", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 470, "start_aa": "Ser", "end_pos": 470, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser470", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Ser471", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 471, "start_aa": "Ser", "end_pos": 471, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser471", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Ser472", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 472, "start_aa": "Ser", "end_pos": 472, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser472", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "474", "end_pos": "474", "site_lbl": "Thr474", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 474, "start_aa": "Thr", "end_pos": 474, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr474", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Ser475", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 475, "start_aa": "Ser", "end_pos": 475, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser475", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "482", "end_pos": "482", "site_lbl": "Ser482", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 482, "start_aa": "Ser", "end_pos": 482, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser482", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Thr483", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 483, "start_aa": "Thr", "end_pos": 483, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr483", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Thr484", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 484, "start_aa": "Thr", "end_pos": 484, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr484", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "485", "end_pos": "485", "site_lbl": "Ser485", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 485, "start_aa": "Ser", "end_pos": 485, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser485", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "486", "end_pos": "486", "site_lbl": "Thr486", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 486, "start_aa": "Thr", "end_pos": 486, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr486", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Ser489", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 489, "start_aa": "Ser", "end_pos": 489, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser489", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q08817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q08817" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "614", "end_pos": "614", "site_lbl": "Thr614", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 614, "start_aa": "Thr", "end_pos": 614, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr614", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Thr214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q08817", "url": "https://www.uniprot.org/uniprotkb/Q08817" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q08817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08817" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005880", "url": "https://www.yeastgenome.org/locus/S000005880" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "462", "end_pos": "462", "site_lbl": "Ser462", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005880", "url": "https://www.yeastgenome.org/locus/S000005880" }, { "database": "iPTMnet", "id": "Q08817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08817" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Thr468", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005880", "url": "https://www.yeastgenome.org/locus/S000005880" }, { "database": "iPTMnet", "id": "Q08817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08817" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Thr46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005880", "url": "https://www.yeastgenome.org/locus/S000005880" }, { "database": "iPTMnet", "id": "Q08817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08817" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "578", "end_pos": "578", "site_lbl": "Ser578", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005880", "url": "https://www.yeastgenome.org/locus/S000005880" }, { "database": "iPTMnet", "id": "Q08817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08817" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "779", "end_pos": "779", "site_lbl": "Ser779", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08817" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005880", "url": "https://www.yeastgenome.org/locus/S000005880" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "784", "end_pos": "784", "site_lbl": "Ser784", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08817" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q08817-1", "start_pos": "789", "end_pos": "789", "site_lbl": "Ser789", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08817" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005880", "url": "https://www.yeastgenome.org/locus/S000005880" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q08817-1" }, { "uniprot_canonical_ac": "Q08919-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08919", "url": "https://www.uniprot.org/uniprotkb/Q08919" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 783, "chemical_mass": 88756.0, "gene_names": "TRE1;TRE1", "protein_name": "Uncharacterized protein TRE1", "disease": [ { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0111030", "name": "hemochromatosis type 3", "description": "A hemochromatosis that has_material_basis_in homozygous or compound heterozygous mutation in the TFR2 gene on chromosome 7q22.", "url": "https://disease-ontology.org/term/DOID:0111030", "evidence": [ { "id": "0111030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111030" } ], "weight": 0.0 }, { "disease_id": "DOID:1724", "name": "duodenal ulcer", "description": "", "url": "https://disease-ontology.org/term/DOID:1724", "evidence": [ { "id": "1724", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1724" } ], "weight": 0.0 }, { "disease_id": "DOID:2352", "name": "hemochromatosis", "description": "A metal metabolism disorder characterized by the accumulation of iron in various organs of the body.", "url": "https://disease-ontology.org/term/DOID:2352", "evidence": [ { "id": "2352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2352" } ], "weight": 0.0 }, { "disease_id": "DOID:374", "name": "nutrition disease", "description": "An acquired metabolic disease that is characterized by an insufficient intake of food or of certain nutrients, by an inability of the body to absorb and use nutrients, or by overconsumption of certain foods.", "url": "https://disease-ontology.org/term/DOID:374", "evidence": [ { "id": "374", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:374" } ], "weight": 0.0 }, { "disease_id": "DOID:4258", "name": "Weissenbacher-Zweymuller syndrome", "description": "An osteochondrodysplasia that results_in shortened long bones and distinct facial abnormalities.", "url": "https://disease-ontology.org/term/DOID:4258", "evidence": [ { "id": "4258", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4258" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "biological_process": [ { "name": "protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043328", "evidence": [ { "database": "UniProtKB", "id": "Q08919", "url": "https://www.uniprot.org/uniprotkb/Q08919" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q08919", "url": "https://www.uniprot.org/uniprotkb/Q08919" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "Q08919", "url": "https://www.uniprot.org/uniprotkb/Q08919" } ], "pmid": "" } ], "molecular_function": [ { "name": "carboxypeptidase activity", "id": "GO:0004180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004180", "evidence": [ { "database": "UniProtKB", "id": "Q08919", "url": "https://www.uniprot.org/uniprotkb/Q08919" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08919-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Asn139", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 139, "start_aa": "Asn", "end_pos": 139, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn139", "evidence": [ { "id": "Q08919", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08919#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08919-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Asn213", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 213, "start_aa": "Asn", "end_pos": 213, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn213", "evidence": [ { "id": "Q08919", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08919#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08919-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Asn529", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 529, "start_aa": "Asn", "end_pos": 529, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn529", "evidence": [ { "id": "Q08919", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08919#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08919-1", "start_pos": "597", "end_pos": "597", "site_lbl": "Ser597", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08919", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08919" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] } ], "record_id": "Q08919-1" }, { "uniprot_canonical_ac": "Q08949-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 612, "chemical_mass": 69694.0, "gene_names": "DDC1;DDC1", "protein_name": "DNA damage checkpoint protein 1", "disease": [], "biological_process": [ { "name": "meiotic recombination checkpoint signaling", "id": "GO:0051598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051598", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "DNA replication checkpoint signaling", "id": "GO:0000076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000076", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "cellular response to ionizing radiation", "id": "GO:0071479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071479", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "mitotic intra-S DNA damage checkpoint signaling", "id": "GO:0031573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031573", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "recombinational repair", "id": "GO:0000725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000725", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "mitotic G1 DNA damage checkpoint signaling", "id": "GO:0031571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031571", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" } ], "cellular_component": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "checkpoint clamp complex", "id": "GO:0030896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030896", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08949-1", "start_pos": "342", "end_pos": "342", "site_lbl": "Thr342", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "20005839", "url": "https://glygen.org/publication/PubMed/20005839" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Ser410", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "413", "end_pos": "413", "site_lbl": "Ser413", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Ser417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Ser429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "433", "end_pos": "433", "site_lbl": "Thr433", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Ser436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q08949", "url": "https://www.uniprot.org/uniprotkb/Q08949" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Ser469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "20005839", "url": "https://glygen.org/publication/PubMed/20005839" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Ser495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "511", "end_pos": "511", "site_lbl": "Ser511", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "517", "end_pos": "517", "site_lbl": "Ser517", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Thr529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "20005839", "url": "https://glygen.org/publication/PubMed/20005839" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "556", "end_pos": "556", "site_lbl": "Ser556", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "580", "end_pos": "580", "site_lbl": "Ser580", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "20005839", "url": "https://glygen.org/publication/PubMed/20005839" }, { "database": "SGD", "id": "S000006115", "url": "https://www.yeastgenome.org/locus/S000006115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08949-1", "start_pos": "602", "end_pos": "602", "site_lbl": "Thr602", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "18541674", "url": "https://glygen.org/publication/PubMed/18541674" }, { "database": "PubMed", "id": "20005839", "url": "https://glygen.org/publication/PubMed/20005839" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "Q08949", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08949" }, { "database": "PubMed", "id": "18541674", "url": "https://glygen.org/publication/PubMed/18541674" }, { "database": "PubMed", "id": "20005839", "url": "https://glygen.org/publication/PubMed/20005839" } ] } ] } ], "record_id": "Q08949-1" }, { "uniprot_canonical_ac": "Q08955-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 156, "chemical_mass": 18307.0, "gene_names": "CSM4;CSM4", "protein_name": "Chromosome segregation in meiosis protein 4", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "pmid": "" }, { "name": "meiotic nuclear membrane microtubule tethering complex", "id": "GO:0034993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034993", "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "pmid": "" } ], "biological_process": [ { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "pmid": "" }, { "name": "meiotic chromosome segregation", "id": "GO:0045132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045132", "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "pmid": "" }, { "name": "meiotic telomere clustering", "id": "GO:0045141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045141", "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "pmid": "" }, { "name": "regulation of reciprocal meiotic recombination", "id": "GO:0010520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010520", "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytoskeleton-nuclear membrane anchor activity", "id": "GO:0140444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140444", "evidence": [ { "database": "UniProtKB", "id": "Q08955", "url": "https://www.uniprot.org/uniprotkb/Q08955" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q08955-1" }, { "uniprot_canonical_ac": "Q08975-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08975", "url": "https://www.uniprot.org/uniprotkb/Q08975" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 551, "chemical_mass": 61334.0, "gene_names": "THI21;THI21", "protein_name": "Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q08975", "url": "https://www.uniprot.org/uniprotkb/Q08975" } ], "pmid": "" }, { "name": "hydroxymethylpyrimidine kinase activity", "id": "GO:0008902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008902", "evidence": [ { "database": "UniProtKB", "id": "Q08975", "url": "https://www.uniprot.org/uniprotkb/Q08975" } ], "pmid": "" }, { "name": "phosphomethylpyrimidine kinase activity", "id": "GO:0008972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008972", "evidence": [ { "database": "UniProtKB", "id": "Q08975", "url": "https://www.uniprot.org/uniprotkb/Q08975" } ], "pmid": "" }, { "name": "thiaminase activity", "id": "GO:0050334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050334", "evidence": [ { "database": "UniProtKB", "id": "Q08975", "url": "https://www.uniprot.org/uniprotkb/Q08975" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q08975", "url": "https://www.uniprot.org/uniprotkb/Q08975" } ], "pmid": "" } ], "biological_process": [ { "name": "thiamine diphosphate biosynthetic process", "id": "GO:0009229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009229", "evidence": [ { "database": "UniProtKB", "id": "Q08975", "url": "https://www.uniprot.org/uniprotkb/Q08975" } ], "pmid": "" }, { "name": "thiamine biosynthetic process", "id": "GO:0009228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009228", "evidence": [ { "database": "UniProtKB", "id": "Q08975", "url": "https://www.uniprot.org/uniprotkb/Q08975" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q08975-1" }, { "uniprot_canonical_ac": "Q08981-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08981", "url": "https://www.uniprot.org/uniprotkb/Q08981" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 209, "chemical_mass": 23870.0, "gene_names": "ACM1;ACM1", "protein_name": "APC/C-CDH1 modulator 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08981", "url": "https://www.uniprot.org/uniprotkb/Q08981" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08981", "url": "https://www.uniprot.org/uniprotkb/Q08981" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q08981", "url": "https://www.uniprot.org/uniprotkb/Q08981" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q08981", "url": "https://www.uniprot.org/uniprotkb/Q08981" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "Q08981", "url": "https://www.uniprot.org/uniprotkb/Q08981" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-protein transferase inhibitor activity", "id": "GO:0055105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055105", "evidence": [ { "database": "UniProtKB", "id": "Q08981", "url": "https://www.uniprot.org/uniprotkb/Q08981" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08981-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Thr161", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q08981", "url": "https://www.uniprot.org/uniprotkb/Q08981" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18287090", "url": "https://glygen.org/publication/PubMed/18287090" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "18287090", "url": "https://glygen.org/publication/PubMed/18287090" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "18287090", "url": "https://glygen.org/publication/PubMed/18287090" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "18287090", "url": "https://glygen.org/publication/PubMed/18287090" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "18287090", "url": "https://glygen.org/publication/PubMed/18287090" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Thr173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "18287090", "url": "https://glygen.org/publication/PubMed/18287090" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Thr189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q08981", "url": "https://www.uniprot.org/uniprotkb/Q08981" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18287090", "url": "https://glygen.org/publication/PubMed/18287090" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Thr41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q08981", "url": "https://www.uniprot.org/uniprotkb/Q08981" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "18287090", "url": "https://glygen.org/publication/PubMed/18287090" }, { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q08981-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006188", "url": "https://www.yeastgenome.org/locus/S000006188" }, { "database": "iPTMnet", "id": "Q08981", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q08981" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q08981-1" }, { "uniprot_canonical_ac": "Q08989-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q08989", "url": "https://www.uniprot.org/uniprotkb/Q08989" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 487, "chemical_mass": 54538.0, "gene_names": "", "protein_name": "Uncharacterized protein YPL277C", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q08989", "url": "https://www.uniprot.org/uniprotkb/Q08989" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08989-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Asn150", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 150, "start_aa": "Asn", "end_pos": 150, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn150", "evidence": [ { "id": "Q08989", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08989#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08989-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Asn220", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 220, "start_aa": "Asn", "end_pos": 220, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn220", "evidence": [ { "id": "Q08989", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08989#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08989-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Asn304", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 304, "start_aa": "Asn", "end_pos": 304, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn304", "evidence": [ { "id": "Q08989", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08989#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08989-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Asn367", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 367, "start_aa": "Asn", "end_pos": 367, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn367", "evidence": [ { "id": "Q08989", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08989#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08989-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Asn40", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 40, "start_aa": "Asn", "end_pos": 40, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn40", "evidence": [ { "id": "Q08989", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08989#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08989-1", "start_pos": "442", "end_pos": "442", "site_lbl": "Asn442", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 442, "start_aa": "Asn", "end_pos": 442, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn442", "evidence": [ { "id": "Q08989", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08989#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08989-1", "start_pos": "448", "end_pos": "448", "site_lbl": "Asn448", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 448, "start_aa": "Asn", "end_pos": 448, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn448", "evidence": [ { "id": "Q08989", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08989#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08989-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Asn68", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 68, "start_aa": "Asn", "end_pos": 68, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn68", "evidence": [ { "id": "Q08989", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08989#ptm_processing" } ] } ] } ], "record_id": "Q08989-1" }, { "uniprot_canonical_ac": "Q12020-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12020", "url": "https://www.uniprot.org/uniprotkb/Q12020" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 392, "chemical_mass": 45140.0, "gene_names": "SRL2;SRL2", "protein_name": "Protein SRL2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12020", "url": "https://www.uniprot.org/uniprotkb/Q12020" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12020", "url": "https://www.uniprot.org/uniprotkb/Q12020" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "Q12020", "url": "https://www.uniprot.org/uniprotkb/Q12020" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12020-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Thr116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" }, { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12020", "url": "https://www.uniprot.org/uniprotkb/Q12020" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Thr133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12020", "url": "https://www.uniprot.org/uniprotkb/Q12020" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Thr145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Ser262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" }, { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Ser276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" }, { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Ser278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" }, { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Ser62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12020-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Thr64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004072", "url": "https://www.yeastgenome.org/locus/S000004072" }, { "database": "iPTMnet", "id": "Q12020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12020" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12020-1" }, { "uniprot_canonical_ac": "Q12021-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12021", "url": "https://www.uniprot.org/uniprotkb/Q12021" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 506, "chemical_mass": 58230.0, "gene_names": "RAD28;RAD28;YD9813.08c", "protein_name": "Radiation-sensitive protein 28", "disease": [ { "disease_id": "DOID:0060240", "name": "UV-sensitive syndrome", "description": "A skin disease characterized by photosensitivity and liver spots (solar lentigines).", "url": "https://disease-ontology.org/term/DOID:0060240", "evidence": [ { "id": "0060240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060240" } ], "weight": 0.0 }, { "disease_id": "DOID:0080907", "name": "Cockayne syndrome A", "description": "A Cockayne syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding the group 8 excision repair cross-complementing protein on chromosome 5q11.", "url": "https://disease-ontology.org/term/DOID:0080907", "evidence": [ { "id": "0080907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080907" } ], "weight": 0.0 }, { "disease_id": "DOID:2962", "name": "Cockayne syndrome", "description": "A syndrome that is characterized by an abnormally small head size (microcephaly), a failure to gain weight and grow at the expected rate (failure to thrive) leading to very short stature, and delayed development.", "url": "https://disease-ontology.org/term/DOID:2962", "evidence": [ { "id": "2962", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2962" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Cul4A-RING E3 ubiquitin ligase complex", "id": "GO:0031464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031464", "evidence": [ { "database": "UniProtKB", "id": "Q12021", "url": "https://www.uniprot.org/uniprotkb/Q12021" } ], "pmid": "" }, { "name": "nucleotide-excision repair complex", "id": "GO:0000109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000109", "evidence": [ { "database": "UniProtKB", "id": "Q12021", "url": "https://www.uniprot.org/uniprotkb/Q12021" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12021", "url": "https://www.uniprot.org/uniprotkb/Q12021" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q12021", "url": "https://www.uniprot.org/uniprotkb/Q12021" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q12021", "url": "https://www.uniprot.org/uniprotkb/Q12021" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q12021", "url": "https://www.uniprot.org/uniprotkb/Q12021" } ], "pmid": "" }, { "name": "transcription-coupled nucleotide-excision repair", "id": "GO:0006283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006283", "evidence": [ { "database": "UniProtKB", "id": "Q12021", "url": "https://www.uniprot.org/uniprotkb/Q12021" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q12021-1" }, { "uniprot_canonical_ac": "Q12038-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1033, "chemical_mass": 114513.0, "gene_names": "SRO7;SNI1;SOP1;SRO7;YP9367.12", "protein_name": "Exocytosis protein SRO7", "disease": [ { "disease_id": "DOID:1319", "name": "brain cancer", "description": "A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain.", "url": "https://disease-ontology.org/term/DOID:1319", "evidence": [ { "id": "1319", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1319" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:263", "name": "kidney cancer", "description": "A urinary system cancer that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:263", "evidence": [ { "id": "263", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:263" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 }, { "disease_id": "DOID:769", "name": "neuroblastoma", "description": "An autonomic nervous system neoplasm that derives_from immature nerve cells.", "url": "https://disease-ontology.org/term/DOID:769", "evidence": [ { "id": "769", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:769" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "myosin II binding", "id": "GO:0045159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045159", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" }, { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12038-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] } ] }, { "uniprot_canonical_ac": "Q12038-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12038-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12038-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q12038-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12038-1", "start_pos": "591", "end_pos": "591", "site_lbl": "Ser591", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12038-1", "start_pos": "602", "end_pos": "602", "site_lbl": "Ser602", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12038", "url": "https://www.uniprot.org/uniprotkb/Q12038" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12038-1", "start_pos": "670", "end_pos": "670", "site_lbl": "Tyr670", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12038-1", "start_pos": "723", "end_pos": "723", "site_lbl": "Ser723", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12038-1", "start_pos": "981", "end_pos": "981", "site_lbl": "Ser981", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12038-1", "start_pos": "982", "end_pos": "982", "site_lbl": "Ser982", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006236", "url": "https://www.yeastgenome.org/locus/S000006236" }, { "database": "iPTMnet", "id": "Q12038", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12038" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "Q12038-1" }, { "uniprot_canonical_ac": "Q12043-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12043", "url": "https://www.uniprot.org/uniprotkb/Q12043" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 749, "chemical_mass": 84716.0, "gene_names": "TGL5;STC2;TGL5;YOR29-32;YOR2964C", "protein_name": "Triacylglycerol lipase 5", "disease": [], "cellular_component": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "Q12043", "url": "https://www.uniprot.org/uniprotkb/Q12043" } ], "pmid": "" } ], "molecular_function": [ { "name": "lysophosphatidic acid acyltransferase activity", "id": "GO:0042171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042171", "evidence": [ { "database": "UniProtKB", "id": "Q12043", "url": "https://www.uniprot.org/uniprotkb/Q12043" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q12043", "url": "https://www.uniprot.org/uniprotkb/Q12043" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q12043", "url": "https://www.uniprot.org/uniprotkb/Q12043" } ], "pmid": "" }, { "name": "triglyceride mobilization", "id": "GO:0006642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006642", "evidence": [ { "database": "UniProtKB", "id": "Q12043", "url": "https://www.uniprot.org/uniprotkb/Q12043" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "Q12043", "url": "https://www.uniprot.org/uniprotkb/Q12043" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12043-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Asn270", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 270, "start_aa": "Asn", "end_pos": 270, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn270", "evidence": [ { "id": "Q12043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q12043#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Asn289", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 289, "start_aa": "Asn", "end_pos": 289, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn289", "evidence": [ { "id": "Q12043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q12043#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Asn297", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 297, "start_aa": "Asn", "end_pos": 297, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn297", "evidence": [ { "id": "Q12043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q12043#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Asn304", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 304, "start_aa": "Asn", "end_pos": 304, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn304", "evidence": [ { "id": "Q12043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q12043#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Asn321", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 321, "start_aa": "Asn", "end_pos": 321, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn321", "evidence": [ { "id": "Q12043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q12043#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "474", "end_pos": "474", "site_lbl": "Asn474", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 474, "start_aa": "Asn", "end_pos": 474, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn474", "evidence": [ { "id": "Q12043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q12043#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "589", "end_pos": "589", "site_lbl": "Asn589", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 589, "start_aa": "Asn", "end_pos": 589, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn589", "evidence": [ { "id": "Q12043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q12043#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "680", "end_pos": "680", "site_lbl": "Asn680", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 680, "start_aa": "Asn", "end_pos": 680, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn680", "evidence": [ { "id": "Q12043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q12043#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "714", "end_pos": "714", "site_lbl": "Asn714", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 714, "start_aa": "Asn", "end_pos": 714, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn714", "evidence": [ { "id": "Q12043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q12043#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "742", "end_pos": "742", "site_lbl": "Asn742", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 742, "start_aa": "Asn", "end_pos": 742, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn742", "evidence": [ { "id": "Q12043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q12043#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Thr21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "532", "end_pos": "532", "site_lbl": "Thr532", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Ser542", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Ser604", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "606", "end_pos": "606", "site_lbl": "Ser606", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "618", "end_pos": "618", "site_lbl": "Ser618", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Ser620", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "622", "end_pos": "622", "site_lbl": "Ser622", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "624", "end_pos": "624", "site_lbl": "Ser624", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "625", "end_pos": "625", "site_lbl": "Thr625", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Ser626", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "645", "end_pos": "645", "site_lbl": "Ser645", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12043", "url": "https://www.uniprot.org/uniprotkb/Q12043" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Ser647", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "660", "end_pos": "660", "site_lbl": "Ser660", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12043-1", "start_pos": "676", "end_pos": "676", "site_lbl": "Tyr676", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005607", "url": "https://www.yeastgenome.org/locus/S000005607" }, { "database": "iPTMnet", "id": "Q12043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12043" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12043-1" }, { "uniprot_canonical_ac": "Q12083-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 715, "chemical_mass": 82001.0, "gene_names": "MLH3;MLH3;P2550", "protein_name": "DNA mismatch repair protein MLH3", "disease": [ { "disease_id": "DOID:0070276", "name": "hereditary nonpolyposis colorectal cancer type 7", "description": "A Lynch syndrome that has_material_basis_in mutation in the MLH3 gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0070276", "evidence": [ { "id": "0070276", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070276" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:3883", "name": "Lynch syndrome", "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.", "url": "https://disease-ontology.org/term/DOID:3883", "evidence": [ { "id": "3883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3883" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "meiotic mismatch repair", "id": "GO:0000710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000710", "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "pmid": "" }, { "name": "mismatch repair", "id": "GO:0006298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006298", "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "pmid": "" }, { "name": "mismatched DNA binding", "id": "GO:0030983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030983", "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "pmid": "" }, { "name": "ATP-dependent DNA damage sensor activity", "id": "GO:0140664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140664", "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "pmid": "" }, { "name": "mismatch repair complex", "id": "GO:0032300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032300", "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "pmid": "" }, { "name": "MutLgamma complex", "id": "GO:0097587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097587", "evidence": [ { "database": "UniProtKB", "id": "Q12083", "url": "https://www.uniprot.org/uniprotkb/Q12083" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12083-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ser484", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006085", "url": "https://www.yeastgenome.org/locus/S000006085" }, { "database": "iPTMnet", "id": "Q12083", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12083" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "Q12083-1" }, { "uniprot_canonical_ac": "Q12143-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12143", "url": "https://www.uniprot.org/uniprotkb/Q12143" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 216, "chemical_mass": 25416.0, "gene_names": "NSL1;NSL1", "protein_name": "Kinetochore-associated protein NSL1", "disease": [], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "Q12143", "url": "https://www.uniprot.org/uniprotkb/Q12143" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12143", "url": "https://www.uniprot.org/uniprotkb/Q12143" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q12143", "url": "https://www.uniprot.org/uniprotkb/Q12143" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "Q12143", "url": "https://www.uniprot.org/uniprotkb/Q12143" } ], "pmid": "" }, { "name": "MIS12/MIND type complex", "id": "GO:0000444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000444", "evidence": [ { "database": "UniProtKB", "id": "Q12143", "url": "https://www.uniprot.org/uniprotkb/Q12143" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q12143", "url": "https://www.uniprot.org/uniprotkb/Q12143" } ], "pmid": "" }, { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "Q12143", "url": "https://www.uniprot.org/uniprotkb/Q12143" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q12143", "url": "https://www.uniprot.org/uniprotkb/Q12143" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "Q12143", "url": "https://www.uniprot.org/uniprotkb/Q12143" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12143-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Thr114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12143" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006154", "url": "https://www.yeastgenome.org/locus/S000006154" } ] } ] }, { "uniprot_canonical_ac": "Q12143-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ser159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006154", "url": "https://www.yeastgenome.org/locus/S000006154" }, { "database": "iPTMnet", "id": "Q12143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12143" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12143-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Ser165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006154", "url": "https://www.yeastgenome.org/locus/S000006154" }, { "database": "iPTMnet", "id": "Q12143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12143" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12143-1" }, { "uniprot_canonical_ac": "Q12146-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12146", "url": "https://www.uniprot.org/uniprotkb/Q12146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 194, "chemical_mass": 21952.0, "gene_names": "PSF3;PSF3", "protein_name": "DNA replication complex GINS protein PSF3", "disease": [ { "disease_id": "DOID:0060306", "name": "Meier-Gorlin syndrome", "description": "A syndrome that is characterized by bilateral underdevelopment of the external ear, short stature, absent or underdeveloped patellae and severe prenatal and postnatal growth retardation.", "url": "https://disease-ontology.org/term/DOID:0060306", "evidence": [ { "id": "0060306", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060306" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "DNA replication preinitiation complex", "id": "GO:0031261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031261", "evidence": [ { "database": "UniProtKB", "id": "Q12146", "url": "https://www.uniprot.org/uniprotkb/Q12146" } ], "pmid": "" }, { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "Q12146", "url": "https://www.uniprot.org/uniprotkb/Q12146" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12146", "url": "https://www.uniprot.org/uniprotkb/Q12146" } ], "pmid": "" }, { "name": "GINS complex", "id": "GO:0000811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000811", "evidence": [ { "database": "UniProtKB", "id": "Q12146", "url": "https://www.uniprot.org/uniprotkb/Q12146" } ], "pmid": "" }, { "name": "CMG complex", "id": "GO:0071162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071162", "evidence": [ { "database": "UniProtKB", "id": "Q12146", "url": "https://www.uniprot.org/uniprotkb/Q12146" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "Q12146", "url": "https://www.uniprot.org/uniprotkb/Q12146" } ], "pmid": "" }, { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "Q12146", "url": "https://www.uniprot.org/uniprotkb/Q12146" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "Q12146", "url": "https://www.uniprot.org/uniprotkb/Q12146" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q12146", "url": "https://www.uniprot.org/uniprotkb/Q12146" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q12146-1" }, { "uniprot_canonical_ac": "Q12149-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 733, "chemical_mass": 84039.0, "gene_names": "RRP6;RRP6;UNC733", "protein_name": "Exosome complex exonuclease RRP6", "disease": [ { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "U1 snRNA 3'-end processing", "id": "GO:0034473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034473", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "U5 snRNA 3'-end processing", "id": "GO:0034476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034476", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent mRNA catabolic process", "id": "GO:0071042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071042", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "regulation of telomere maintenance", "id": "GO:0032204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032204", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "histone mRNA catabolic process", "id": "GO:0071044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071044", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000973", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "poly(A)-dependent snoRNA 3'-end processing", "id": "GO:0071051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071051", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snoRNA catabolic process", "id": "GO:0071036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071036", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snRNA catabolic process", "id": "GO:0071037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071037", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent CUT catabolic process", "id": "GO:0071039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071039", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent antisense transcript catabolic process", "id": "GO:0071040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071040", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" }, { "name": "rRNA primary transcript binding", "id": "GO:0042134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042134", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12149-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Tyr406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Thr410", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Ser412", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Ser417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Thr515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "520", "end_pos": "520", "site_lbl": "Thr520", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "16829593", "url": "https://glygen.org/publication/PubMed/16829593" }, { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "PubMed", "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Ser640", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "645", "end_pos": "645", "site_lbl": "Ser645", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "689", "end_pos": "689", "site_lbl": "Ser689", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "709", "end_pos": "709", "site_lbl": "Ser709", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005527", "url": "https://www.yeastgenome.org/locus/S000005527" }, { "database": "iPTMnet", "id": "Q12149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12149" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Gln133", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "No significant effects on growth rates and degradation of 5' ETSRNA, increased accumulation of extended forms of snR40 snoRNA and 5.8S + 30 nt RNA; when associated with A-142.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "16882719", "url": "https://glygen.org/publication/PubMed/16882719" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Asn142", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "No significant effects on growth rates and degradation of 5' ETSRNA, increased accumulation of extended forms of snR40 snoRNA and 5.8S + 30 nt RNA; when associated with A-133.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "16882719", "url": "https://glygen.org/publication/PubMed/16882719" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Asp238", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Temperature-sensitive mutant. Abolishes exonuclease activity and increases accumulation of 5.8S + 30 nt RNA, 5' ETSRNA, U24 + 3 nt RNA and poly(A)+ snoRNAs. No effect on subcellular localization.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "12923258", "url": "https://glygen.org/publication/PubMed/12923258" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Glu240", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Temperature-sensitive mutant. Abolishes exonuclease activity and increases accumulation of 5.8S + 30 nt RNA, 5' ETSRNA and U24 + 3 nt RNA.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "12923258", "url": "https://glygen.org/publication/PubMed/12923258" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Asp296", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Temperature-sensitive mutant. Abolishes exonuclease activity and increases accumulation of 5.8S + 30 nt RNA, 5' ETSRNA and U24 + 3 nt RNA. No effect on subcellular localization.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "12923258", "url": "https://glygen.org/publication/PubMed/12923258" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Tyr361", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Temperature-sensitive mutant. Abolishes exonuclease activity and increases accumulation of 5.8S + 30 nt RNA, 5' ETSRNA and U24 + 3 nt RNA.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "12923258", "url": "https://glygen.org/publication/PubMed/12923258" } ] }, { "sequence_org": "Y", "sequence_mut": "F", "comment": "Temperature-sensitive mutant. Abolishes exonuclease activity and increases accumulation of 5.8S + 30 nt RNA, 5' ETSRNA and U24 + 3 nt RNA. No effect on subcellular localization.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "12923258", "url": "https://glygen.org/publication/PubMed/12923258" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Asp365", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Temperature-sensitive mutant. Abolishes exonuclease activity and increases accumulation of 5.8S + 30 nt RNA, 5' ETSRNA and U24 + 3 nt RNA.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "12923258", "url": "https://glygen.org/publication/PubMed/12923258" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "448", "end_pos": "448", "site_lbl": "Trp448", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "No significant effects on growth at different temperatures, in vitro exonuclease activity and processing 5.8S rRNA, U24 snoRNA and ETSRNA.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "12923258", "url": "https://glygen.org/publication/PubMed/12923258" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "449", "end_pos": "449", "site_lbl": "Arg449", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No significant effects on growth at different temperatures and processing 5.8S rRNA, U24 snoRNA and ETSRNA. Reduces exonuclease activity.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "12923258", "url": "https://glygen.org/publication/PubMed/12923258" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "456", "end_pos": "456", "site_lbl": "Asp456", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "No significant effects on growth at different temperatures, in vitro exonuclease activity and processing 5.8S rRNA, U24 snoRNA and ETSRNA.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "12923258", "url": "https://glygen.org/publication/PubMed/12923258" } ] } ] }, { "uniprot_canonical_ac": "Q12149-1", "start_pos": "457", "end_pos": "457", "site_lbl": "Asp457", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "No significant effects on growth rates at different temperatures, processing 5' ETSRNA and poly(A)+ snoRNAs, non-significant or moderate defects in 5.8S rRNA processing resulting in accumulation of 5.8S + 30 nt RNA, increased accumulation of extended forms of snR40 snoRNA and U24 + 3 nt snoRNA. Reduces exonuclease activity. No effect on subcellular localization.", "evidence": [ { "database": "UniProtKB", "id": "Q12149", "url": "https://www.uniprot.org/uniprotkb/Q12149" }, { "database": "PubMed", "id": "16882719", "url": "https://glygen.org/publication/PubMed/16882719" }, { "database": "PubMed", "id": "12923258", "url": "https://glygen.org/publication/PubMed/12923258" } ] } ] } ], "record_id": "Q12149-1" }, { "uniprot_canonical_ac": "Q12159-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 226, "chemical_mass": 24956.0, "gene_names": "YRA1;D9481.2;D9509.1;SHE11;YRA1", "protein_name": "RNA annealing protein YRA1", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" } ], "pmid": "" }, { "name": "DNA/RNA hybrid binding", "id": "GO:0071667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071667", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" } ], "pmid": "" }, { "name": "RNA helicase inhibitor activity", "id": "GO:1990119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990119", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" } ], "pmid": "" }, { "name": "transcription export complex", "id": "GO:0000346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000346", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" } ], "pmid": "" }, { "name": "transcription-coupled nucleotide-excision repair", "id": "GO:0006283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006283", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12159-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Ser100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Ser111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Thr74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12159-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12159", "url": "https://www.uniprot.org/uniprotkb/Q12159" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "Q12159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12159" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002789", "url": "https://www.yeastgenome.org/locus/S000002789" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12159-1" }, { "uniprot_canonical_ac": "Q12230-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 341, "chemical_mass": 38071.0, "gene_names": "LSP1;LSP1", "protein_name": "Sphingolipid long chain base-responsive protein LSP1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" }, { "name": "eisosome", "id": "GO:0032126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032126", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" }, { "name": "eisosome filament", "id": "GO:0036286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036286", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" }, { "name": "membrane organization", "id": "GO:0061024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" }, { "name": "response to heat", "id": "GO:0009408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009408", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" }, { "name": "eisosome assembly", "id": "GO:0070941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070941", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12230-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Thr233", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 233, "start_aa": "Thr", "end_pos": 233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12230", "url": "https://www.uniprot.org/uniprotkb/Q12230" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "PubMed", "id": "19269952", "url": "https://glygen.org/publication/PubMed/19269952" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Ser131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "PubMed", "id": "19269952", "url": "https://glygen.org/publication/PubMed/19269952" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Thr271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ser273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Thr277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Ser336", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q12230-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005925", "url": "https://www.yeastgenome.org/locus/S000005925" }, { "database": "iPTMnet", "id": "Q12230", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12230" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12230-1" }, { "uniprot_canonical_ac": "Q12248-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 94, "chemical_mass": 10516.0, "gene_names": "DAD1;DAD1", "protein_name": "DASH complex subunit DAD1", "disease": [], "biological_process": [ { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "pmid": "" }, { "name": "positive regulation of microtubule polymerization", "id": "GO:0031116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031116", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "pmid": "" }, { "name": "positive regulation of attachment of spindle microtubules to kinetochore", "id": "GO:0051987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051987", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "pmid": "" }, { "name": "mitotic sister chromatid biorientation", "id": "GO:1990758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990758", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "pmid": "" }, { "name": "protein transport along microtubule to mitotic spindle pole body", "id": "GO:1990976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990976", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "pmid": "" }, { "name": "DASH complex", "id": "GO:0042729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042729", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "pmid": "" }, { "name": "mitotic spindle pole body", "id": "GO:0044732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044732", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12248-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002423", "url": "https://www.yeastgenome.org/locus/S000002423" }, { "database": "iPTMnet", "id": "Q12248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12248" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12248-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Tyr70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002423", "url": "https://www.yeastgenome.org/locus/S000002423" }, { "database": "iPTMnet", "id": "Q12248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12248" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12248-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002423", "url": "https://www.yeastgenome.org/locus/S000002423" }, { "database": "iPTMnet", "id": "Q12248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12248" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12248-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12248" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002423", "url": "https://www.yeastgenome.org/locus/S000002423" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12248-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Thr87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002423", "url": "https://www.yeastgenome.org/locus/S000002423" }, { "database": "iPTMnet", "id": "Q12248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12248" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12248-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Ser89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "Q12248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12248" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "Q12248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12248" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002423", "url": "https://www.yeastgenome.org/locus/S000002423" }, { "database": "iPTMnet", "id": "Q12248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12248" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12248-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12248" }, { "database": "SGD", "id": "S000002423", "url": "https://www.yeastgenome.org/locus/S000002423" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12248-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Thr93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002423", "url": "https://www.yeastgenome.org/locus/S000002423" }, { "database": "iPTMnet", "id": "Q12248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12248" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12248-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Glu50", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "D", "comment": "Perturbs DASH complex formation and weakens microtubule attachments. Decreases sporulation efficiency and spore viability.", "evidence": [ { "database": "UniProtKB", "id": "Q12248", "url": "https://www.uniprot.org/uniprotkb/Q12248" }, { "database": "PubMed", "id": "36651597", "url": "https://glygen.org/publication/PubMed/36651597" } ] } ] } ], "record_id": "Q12248-1" }, { "uniprot_canonical_ac": "Q12250-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12250", "url": "https://www.uniprot.org/uniprotkb/Q12250" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 445, "chemical_mass": 51768.0, "gene_names": "RPN5;D1572;NAS5;RPN5", "protein_name": "26S proteasome regulatory subunit RPN5", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "proteasome storage granule", "id": "GO:0034515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034515", "evidence": [ { "database": "UniProtKB", "id": "Q12250", "url": "https://www.uniprot.org/uniprotkb/Q12250" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12250", "url": "https://www.uniprot.org/uniprotkb/Q12250" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "Q12250", "url": "https://www.uniprot.org/uniprotkb/Q12250" } ], "pmid": "" }, { "name": "proteasome regulatory particle, lid subcomplex", "id": "GO:0008541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008541", "evidence": [ { "database": "UniProtKB", "id": "Q12250", "url": "https://www.uniprot.org/uniprotkb/Q12250" } ], "pmid": "" }, { "name": "COP9 signalosome", "id": "GO:0008180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008180", "evidence": [ { "database": "UniProtKB", "id": "Q12250", "url": "https://www.uniprot.org/uniprotkb/Q12250" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q12250", "url": "https://www.uniprot.org/uniprotkb/Q12250" } ], "pmid": "" }, { "name": "protein deneddylation", "id": "GO:0000338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000338", "evidence": [ { "database": "UniProtKB", "id": "Q12250", "url": "https://www.uniprot.org/uniprotkb/Q12250" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12250-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002306", "url": "https://www.yeastgenome.org/locus/S000002306" }, { "database": "iPTMnet", "id": "Q12250", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12250" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12250-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Tyr13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002306", "url": "https://www.yeastgenome.org/locus/S000002306" }, { "database": "iPTMnet", "id": "Q12250", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12250" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12250-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002306", "url": "https://www.yeastgenome.org/locus/S000002306" }, { "database": "iPTMnet", "id": "Q12250", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12250" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12250-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12250", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12250" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000002306", "url": "https://www.yeastgenome.org/locus/S000002306" } ] } ] }, { "uniprot_canonical_ac": "Q12250-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Ser295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002306", "url": "https://www.yeastgenome.org/locus/S000002306" }, { "database": "iPTMnet", "id": "Q12250", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12250" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12250-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002306", "url": "https://www.yeastgenome.org/locus/S000002306" }, { "database": "iPTMnet", "id": "Q12250", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12250" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12250-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Tyr95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12250", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12250" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] } ], "record_id": "Q12250-1" }, { "uniprot_canonical_ac": "Q12271-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1107, "chemical_mass": 124577.0, "gene_names": "INP53;INP53;SJL3;SOP2;YOR3231w", "protein_name": "Polyphosphatidylinositol phosphatase INP53", "disease": [ { "disease_id": "DOID:0060894", "name": "early-onset Parkinson's disease", "description": "A Parkinson's disease characterized by onset of motor symptoms earlier than typically seen, usually prior to 50 years of age.", "url": "https://disease-ontology.org/term/DOID:0060894", "evidence": [ { "id": "0060894", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060894" } ], "weight": 0.0 }, { "disease_id": "DOID:0060898", "name": "Parkinson's disease 20", "description": "An early-onset Parkinson disease that has_material_basis_in homozygous mutation in the SYNJ1 gene on chromosome 21q22.", "url": "https://disease-ontology.org/term/DOID:0060898", "evidence": [ { "id": "0060898", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060898" } ], "weight": 0.0 }, { "disease_id": "DOID:0080464", "name": "developmental and epileptic encephalopathy 53", "description": "A developmental and epileptic encephalopathy characterized by infantile onset of intractable seizures, hypotonia, poor or absent global development, severe intellectual disability and spastic quadriplegia that has_material_basis_in homozygous or compound heterozygous mutation in the SYNJ1 gene on chromosome 21q22.", "url": "https://disease-ontology.org/term/DOID:0080464", "evidence": [ { "id": "0080464", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080464" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" }, { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3-phosphate phosphatase activity", "id": "GO:0004438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004438", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate phosphatase activity", "id": "GO:0043812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043812", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity", "id": "GO:0043813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043813", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "id": "GO:0004439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004439", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" }, { "name": "inositol-1,4,5-trisphosphate 5-phosphatase activity", "id": "GO:0052658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052658", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12271-1", "start_pos": "1029", "end_pos": "1029", "site_lbl": "Ser1029", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1029, "start_aa": "Ser", "end_pos": 1029, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1029", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "1031", "end_pos": "1031", "site_lbl": "Ser1031", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1031, "start_aa": "Ser", "end_pos": 1031, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1031", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "1038", "end_pos": "1038", "site_lbl": "Ser1038", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1038, "start_aa": "Ser", "end_pos": 1038, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1038", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "1039", "end_pos": "1039", "site_lbl": "Ser1039", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1039, "start_aa": "Ser", "end_pos": 1039, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1039", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "980", "end_pos": "980", "site_lbl": "Ser980", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 980, "start_aa": "Ser", "end_pos": 980, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser980", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "982", "end_pos": "982", "site_lbl": "Ser982", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 982, "start_aa": "Ser", "end_pos": 982, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser982", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "986", "end_pos": "986", "site_lbl": "Ser986", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 986, "start_aa": "Ser", "end_pos": 986, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser986", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "992", "end_pos": "992", "site_lbl": "Ser992", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 992, "start_aa": "Ser", "end_pos": 992, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser992", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "995", "end_pos": "995", "site_lbl": "Ser995", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 995, "start_aa": "Ser", "end_pos": 995, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser995", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "997", "end_pos": "997", "site_lbl": "Ser997", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 997, "start_aa": "Ser", "end_pos": 997, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser997", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "998", "end_pos": "998", "site_lbl": "Ser998", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 998, "start_aa": "Ser", "end_pos": 998, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser998", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12271", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12271" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "1030", "end_pos": "1030", "site_lbl": "Thr1030", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "1035", "end_pos": "1035", "site_lbl": "Ser1035", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "1046", "end_pos": "1046", "site_lbl": "Ser1046", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "1050", "end_pos": "1050", "site_lbl": "Ser1050", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "1061", "end_pos": "1061", "site_lbl": "Thr1061", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "1105", "end_pos": "1105", "site_lbl": "Thr1105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "454", "end_pos": "454", "site_lbl": "Ser454", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Ser489", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "497", "end_pos": "497", "site_lbl": "Ser497", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "820", "end_pos": "820", "site_lbl": "Thr820", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "870", "end_pos": "870", "site_lbl": "Ser870", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "896", "end_pos": "896", "site_lbl": "Ser896", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "903", "end_pos": "903", "site_lbl": "Ser903", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "926", "end_pos": "926", "site_lbl": "Thr926", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "932", "end_pos": "932", "site_lbl": "Ser932", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "933", "end_pos": "933", "site_lbl": "Ser933", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "934", "end_pos": "934", "site_lbl": "Ser934", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "956", "end_pos": "956", "site_lbl": "Thr956", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "973", "end_pos": "973", "site_lbl": "Ser973", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "975", "end_pos": "975", "site_lbl": "Ser975", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "988", "end_pos": "988", "site_lbl": "Thr988", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "993", "end_pos": "993", "site_lbl": "Thr993", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005635", "url": "https://www.yeastgenome.org/locus/S000005635" }, { "database": "iPTMnet", "id": "Q12271", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12271" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "421", "end_pos": "421", "site_lbl": "Cys421", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Reduces hydrolysis of PtdIns(4)P; when associated with A-424 and A-427.", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" }, { "database": "PubMed", "id": "12686590", "url": "https://glygen.org/publication/PubMed/12686590" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Cys424", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Reduces hydrolysis of PtdIns(4)P; when associated with A-421 and A-427.", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" }, { "database": "PubMed", "id": "12686590", "url": "https://glygen.org/publication/PubMed/12686590" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "427", "end_pos": "427", "site_lbl": "Arg427", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces hydrolysis of PtdIns(4)P; when associated with A-421 and A-424.", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" }, { "database": "PubMed", "id": "12686590", "url": "https://glygen.org/publication/PubMed/12686590" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "746", "end_pos": "746", "site_lbl": "Asp746", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes hydrolysis of PtdIns(4,5)P2; when associated with A-748.", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" }, { "database": "PubMed", "id": "12686590", "url": "https://glygen.org/publication/PubMed/12686590" } ] } ] }, { "uniprot_canonical_ac": "Q12271-1", "start_pos": "748", "end_pos": "748", "site_lbl": "Asn748", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Abolishes hydrolysis of PtdIns(4,5)P2; when associated with A-746.", "evidence": [ { "database": "UniProtKB", "id": "Q12271", "url": "https://www.uniprot.org/uniprotkb/Q12271" }, { "database": "PubMed", "id": "12686590", "url": "https://glygen.org/publication/PubMed/12686590" } ] } ] } ], "record_id": "Q12271-1" }, { "uniprot_canonical_ac": "Q12277-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 265, "chemical_mass": 29055.0, "gene_names": "RRP42;RRP42", "protein_name": "Exosome complex component RRP42", "disease": [], "biological_process": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "U1 snRNA 3'-end processing", "id": "GO:0034473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034473", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "U5 snRNA 3'-end processing", "id": "GO:0034476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034476", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA 3'-UTR AU-rich region binding", "id": "GO:0035925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035925", "evidence": [ { "database": "UniProtKB", "id": "Q12277", "url": "https://www.uniprot.org/uniprotkb/Q12277" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12277-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Thr18", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 18, "start_aa": "Thr", "end_pos": 18, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr18", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] } ], "record_id": "Q12277-1" }, { "uniprot_canonical_ac": "Q12280-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1495, "chemical_mass": 172830.0, "gene_names": "IQG1;CYK1;IQG1", "protein_name": "Ras GTPase-activating-like protein IQG1", "disease": [ { "disease_id": "DOID:0050563", "name": "nonsyndromic deafness", "description": "An auditory system disease that is associated with permanent hearing loss caused by damage to structures in the inner ear and/or the middle ear, which is not associated with other signs and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050563", "evidence": [ { "id": "0050563", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050563" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "myosin II heavy chain binding", "id": "GO:0032038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032038", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "myosin light chain binding", "id": "GO:0032027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032027", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "myosin II light chain binding", "id": "GO:0032033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032033", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "cellular bud neck contractile ring", "id": "GO:0000142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000142", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "mitotic actomyosin contractile ring", "id": "GO:0110085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110085", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "MIH complex", "id": "GO:0120155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120155", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "mitotic actomyosin contractile ring assembly actin filament organization", "id": "GO:1903479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903479", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "mitotic actomyosin contractile ring assembly", "id": "GO:1903475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903475", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "regulation of actomyosin contractile ring contraction", "id": "GO:0031991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031991", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "protein localization to cell division site", "id": "GO:0072741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072741", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "regulation of cell wall organization or biogenesis", "id": "GO:1903338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903338", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" }, { "name": "regulation of mitotic actomyosin contractile ring contraction", "id": "GO:1903471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903471", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12280-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Thr348", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 348, "start_aa": "Thr", "end_pos": 348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr348", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "1347", "end_pos": "1347", "site_lbl": "Ser1347", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "1409", "end_pos": "1409", "site_lbl": "Ser1409", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Ser257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Thr260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Thr264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Ser268", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Thr299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Thr30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Ser310", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Thr315", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Ser317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Thr338", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Ser343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Tyr353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Thr367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Tyr398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Ser401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "955", "end_pos": "955", "site_lbl": "Ser955", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "956", "end_pos": "956", "site_lbl": "Ser956", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006163", "url": "https://www.yeastgenome.org/locus/S000006163" }, { "database": "iPTMnet", "id": "Q12280", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12280" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12280-1", "start_pos": "457", "end_pos": "457", "site_lbl": "Leu457", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "In IQG1-1; causes a defect in cytokinesis at 37 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "Q12280", "url": "https://www.uniprot.org/uniprotkb/Q12280" }, { "database": "PubMed", "id": "11082046", "url": "https://glygen.org/publication/PubMed/11082046" } ] } ] } ], "record_id": "Q12280-1" }, { "uniprot_canonical_ac": "Q12318-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 242, "chemical_mass": 28251.0, "gene_names": "PSY3;L8039.17;PSY3", "protein_name": "Platinum sensitivity protein 3", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" }, { "name": "Shu complex", "id": "GO:0097196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097196", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" } ], "molecular_function": [ { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" } ], "biological_process": [ { "name": "recombinational repair", "id": "GO:0000725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000725", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" }, { "name": "DNA recombinase assembly", "id": "GO:0000730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000730", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" }, { "name": "error-free translesion synthesis", "id": "GO:0070987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070987", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" }, { "name": "error-free postreplication DNA repair", "id": "GO:0042275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042275", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" }, { "name": "positive regulation of single-strand break repair via homologous recombination", "id": "GO:1903112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903112", "evidence": [ { "database": "UniProtKB", "id": "Q12318", "url": "https://www.uniprot.org/uniprotkb/Q12318" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12318-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12318", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12318" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000004368", "url": "https://www.yeastgenome.org/locus/S000004368" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12318-1" }, { "uniprot_canonical_ac": "Q12330-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 94, "chemical_mass": 10375.0, "gene_names": "SME1;SME1", "protein_name": "Small nuclear ribonucleoprotein E", "disease": [ { "disease_id": "DOID:0080162", "name": "lupus nephritis", "description": "A glomerulonephritis that is characterized by inflammation of the kidneys resulting from systemic lupus erythematosus.", "url": "https://disease-ontology.org/term/DOID:0080162", "evidence": [ { "id": "0080162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080162" } ], "weight": 0.0 }, { "disease_id": "DOID:0110698", "name": "hypotrichosis 1", "description": "A hypotrichosis that has_material_basis_in a autosomal dominant mutation of the APCDD1 gene on chromosome 18p11.22.", "url": "https://disease-ontology.org/term/DOID:0110698", "evidence": [ { "id": "0110698", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110698" } ], "weight": 0.0 }, { "disease_id": "DOID:0110708", "name": "hypotrichosis 11", "description": "A hypotrichosis that has_material_basis_in a autosomal dominant mutation of the SNRPE gene on chromosome 1q32.1.", "url": "https://disease-ontology.org/term/DOID:0110708", "evidence": [ { "id": "0110708", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110708" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:769", "name": "neuroblastoma", "description": "An autonomic nervous system neoplasm that derives_from immature nerve cells.", "url": "https://disease-ontology.org/term/DOID:769", "evidence": [ { "id": "769", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:769" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "pICln-Sm protein complex", "id": "GO:0034715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034715", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "U4 snRNP", "id": "GO:0005687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005687", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" } ], "biological_process": [ { "name": "7-methylguanosine cap hypermethylation", "id": "GO:0036261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036261", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" }, { "name": "splicing factor binding", "id": "GO:1990935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990935", "evidence": [ { "database": "UniProtKB", "id": "Q12330", "url": "https://www.uniprot.org/uniprotkb/Q12330" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12330-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Thr91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005685", "url": "https://www.yeastgenome.org/locus/S000005685" }, { "database": "iPTMnet", "id": "Q12330", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12330" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12330-1", "start_pos": "92", "end_pos": "92", "site_lbl": "Ser92", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005685", "url": "https://www.yeastgenome.org/locus/S000005685" }, { "database": "iPTMnet", "id": "Q12330", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12330" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "Q12330-1" }, { "uniprot_canonical_ac": "Q12341-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 374, "chemical_mass": 43873.0, "gene_names": "HAT1;HAT1;KAT1;LPA16W;YP8132.12", "protein_name": "Histone acetyltransferase type B catalytic subunit", "disease": [], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "pmid": "" }, { "name": "histone acetyltransferase activity", "id": "GO:0004402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "pmid": "" }, { "name": "histone H4 acetyltransferase activity", "id": "GO:0010485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010485", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "pmid": "" }, { "name": "histone acetyltransferase complex", "id": "GO:0000123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000123", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12341-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005922", "url": "https://www.yeastgenome.org/locus/S000005922" }, { "database": "iPTMnet", "id": "Q12341", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12341" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12341-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005922", "url": "https://www.yeastgenome.org/locus/S000005922" }, { "database": "iPTMnet", "id": "Q12341", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12341" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12341-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12341", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12341" }, { "database": "SGD", "id": "S000005922", "url": "https://www.yeastgenome.org/locus/S000005922" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12341-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005922", "url": "https://www.yeastgenome.org/locus/S000005922" }, { "database": "iPTMnet", "id": "Q12341", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12341" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12341-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Trp197", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "E", "comment": "Abolishes interaction with HAT2.", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" }, { "database": "PubMed", "id": "24835250", "url": "https://glygen.org/publication/PubMed/24835250" } ] } ] }, { "uniprot_canonical_ac": "Q12341-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Tyr199", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "E", "comment": "Abolishes interaction with HAT2.", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" }, { "database": "PubMed", "id": "24835250", "url": "https://glygen.org/publication/PubMed/24835250" } ] } ] }, { "uniprot_canonical_ac": "Q12341-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ala202", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "D", "comment": "Impairs interaction with HAT2.", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" }, { "database": "PubMed", "id": "24835250", "url": "https://glygen.org/publication/PubMed/24835250" } ] } ] }, { "uniprot_canonical_ac": "Q12341-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Phe205", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "E", "comment": "Abolishes interaction with HAT2.", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" }, { "database": "PubMed", "id": "24835250", "url": "https://glygen.org/publication/PubMed/24835250" } ] } ] }, { "uniprot_canonical_ac": "Q12341-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Arg214", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs interaction with HAT2.", "evidence": [ { "database": "UniProtKB", "id": "Q12341", "url": "https://www.uniprot.org/uniprotkb/Q12341" }, { "database": "PubMed", "id": "24835250", "url": "https://glygen.org/publication/PubMed/24835250" } ] } ] } ], "record_id": "Q12341-1" }, { "uniprot_canonical_ac": "Q12342-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 491, "chemical_mass": 56549.0, "gene_names": "LDB17;D1575;LDB17", "protein_name": "Protein LDB17", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" } ], "pmid": "" }, { "name": "actin cortical patch localization", "id": "GO:0051666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051666", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" } ], "pmid": "" }, { "name": "actin cortical patch assembly", "id": "GO:0000147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000147", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" } ], "pmid": "" } ], "molecular_function": [ { "name": "Arp2/3 complex binding", "id": "GO:0071933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071933", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12342-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Ser431", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002305", "url": "https://www.yeastgenome.org/locus/S000002305" }, { "database": "iPTMnet", "id": "Q12342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12342" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12342-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Ser435", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12342" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002305", "url": "https://www.yeastgenome.org/locus/S000002305" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12342-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Ser463", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12342" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002305", "url": "https://www.yeastgenome.org/locus/S000002305" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12342-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Ser466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q12342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12342" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002305", "url": "https://www.yeastgenome.org/locus/S000002305" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12342-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Thr468", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12342" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002305", "url": "https://www.yeastgenome.org/locus/S000002305" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12342-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12342", "url": "https://www.uniprot.org/uniprotkb/Q12342" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12342" }, { "database": "SGD", "id": "S000002305", "url": "https://www.yeastgenome.org/locus/S000002305" } ] } ] } ], "record_id": "Q12342-1" }, { "uniprot_canonical_ac": "Q12343-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 284, "chemical_mass": 32205.0, "gene_names": "MED4;MED4;O3630", "protein_name": "Mediator of RNA polymerase II transcription subunit 4", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II core promoter sequence-specific DNA binding", "id": "GO:0000979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000979", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12343-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005700", "url": "https://www.yeastgenome.org/locus/S000005700" }, { "database": "iPTMnet", "id": "Q12343", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12343" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12343-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Thr218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005700", "url": "https://www.yeastgenome.org/locus/S000005700" }, { "database": "iPTMnet", "id": "Q12343", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12343" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12343-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Ser222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005700", "url": "https://www.yeastgenome.org/locus/S000005700" }, { "database": "iPTMnet", "id": "Q12343", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12343" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12343-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005700", "url": "https://www.yeastgenome.org/locus/S000005700" }, { "database": "iPTMnet", "id": "Q12343", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12343" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12343-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Thr237", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P06242-1", "kinase_gene_name": "KIN28", "evidence": [ { "database": "iPTMnet", "id": "Q12343", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12343" }, { "database": "PubMed", "id": "14988503", "url": "https://glygen.org/publication/PubMed/14988503" }, { "database": "PubMed", "id": "15126497", "url": "https://glygen.org/publication/PubMed/15126497" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "kinase_uniprot_canonical_ac": "P37366-1", "kinase_gene_name": "CCL1", "evidence": [ { "database": "iPTMnet", "id": "Q12343", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12343" }, { "database": "PubMed", "id": "14988503", "url": "https://glygen.org/publication/PubMed/14988503" }, { "database": "PubMed", "id": "15126497", "url": "https://glygen.org/publication/PubMed/15126497" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" }, { "database": "iPTMnet", "id": "Q12343", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12343" }, { "database": "PubMed", "id": "15126497", "url": "https://glygen.org/publication/PubMed/15126497" }, { "database": "SGD", "id": "S000005700", "url": "https://www.yeastgenome.org/locus/S000005700" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] } ] }, { "uniprot_canonical_ac": "Q12343-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Thr240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12343", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12343" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005700", "url": "https://www.yeastgenome.org/locus/S000005700" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12343-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12343", "url": "https://www.uniprot.org/uniprotkb/Q12343" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12343", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12343" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005700", "url": "https://www.yeastgenome.org/locus/S000005700" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12343-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Thr248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005700", "url": "https://www.yeastgenome.org/locus/S000005700" }, { "database": "iPTMnet", "id": "Q12343", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12343" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "Q12343-1" }, { "uniprot_canonical_ac": "Q12347-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12347", "url": "https://www.uniprot.org/uniprotkb/Q12347" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 344, "chemical_mass": 40475.0, "gene_names": "HRT3;HRT3", "protein_name": "F-box protein HRT3", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12347", "url": "https://www.uniprot.org/uniprotkb/Q12347" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q12347", "url": "https://www.uniprot.org/uniprotkb/Q12347" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q12347", "url": "https://www.uniprot.org/uniprotkb/Q12347" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "Q12347", "url": "https://www.uniprot.org/uniprotkb/Q12347" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q12347", "url": "https://www.uniprot.org/uniprotkb/Q12347" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q12347", "url": "https://www.uniprot.org/uniprotkb/Q12347" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q12347", "url": "https://www.uniprot.org/uniprotkb/Q12347" } ], "pmid": "" }, { "name": "cellular response to methylmercury", "id": "GO:0071406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071406", "evidence": [ { "database": "UniProtKB", "id": "Q12347", "url": "https://www.uniprot.org/uniprotkb/Q12347" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12347-1", "start_pos": "331", "end_pos": "331", "site_lbl": "Ser331", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004087", "url": "https://www.yeastgenome.org/locus/S000004087" }, { "database": "iPTMnet", "id": "Q12347", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12347" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12347-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Ser339", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004087", "url": "https://www.yeastgenome.org/locus/S000004087" }, { "database": "iPTMnet", "id": "Q12347", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12347" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12347-1" }, { "uniprot_canonical_ac": "Q12363-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 437, "chemical_mass": 48383.0, "gene_names": "WTM1;WTM1;YOR50-20", "protein_name": "Transcriptional modulator WTM1", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "maintenance of protein location in nucleus", "id": "GO:0051457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051457", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "negative regulation of silent mating-type cassette heterochromatin formation", "id": "GO:0061186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061186", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "Rpd3L-Expanded complex", "id": "GO:0070210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070210", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "Rpd3L complex", "id": "GO:0033698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033698", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12363-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Thr107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Thr10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Thr187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Thr307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Thr370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Thr39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Thr406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12363", "url": "https://www.uniprot.org/uniprotkb/Q12363" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "433", "end_pos": "433", "site_lbl": "Thr433", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Ser436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Tyr85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12363-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12363" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005756", "url": "https://www.yeastgenome.org/locus/S000005756" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12363-1" }, { "uniprot_canonical_ac": "Q12366-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 352, "chemical_mass": 40856.0, "gene_names": "NDJ1;NDJ1;TAM1", "protein_name": "Non-disjunction protein 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "pmid": "" }, { "name": "meiotic spindle pole body", "id": "GO:0035974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035974", "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "pmid": "" } ], "molecular_function": [ { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "pmid": "" } ], "biological_process": [ { "name": "meiotic attachment of telomere to nuclear envelope", "id": "GO:0070197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070197", "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "pmid": "" }, { "name": "meiotic telomere clustering", "id": "GO:0045141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045141", "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "pmid": "" }, { "name": "positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric", "id": "GO:2000711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000711", "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "pmid": "" }, { "name": "regulation of reciprocal meiotic recombination", "id": "GO:0010520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010520", "evidence": [ { "database": "UniProtKB", "id": "Q12366", "url": "https://www.uniprot.org/uniprotkb/Q12366" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12366-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Thr74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12366", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12366" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005464", "url": "https://www.yeastgenome.org/locus/S000005464" } ] } ] } ], "record_id": "Q12366-1" }, { "uniprot_canonical_ac": "Q12380-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 294, "chemical_mass": 33560.0, "gene_names": "ATG5;APG5;ATG5;P2601", "protein_name": "Autophagy protein 5", "disease": [ { "disease_id": "DOID:0050951", "name": "hereditary ataxia", "description": "A neurodegenerative disease that is characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements.", "url": "https://disease-ontology.org/term/DOID:0050951", "evidence": [ { "id": "0050951", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050951" } ], "weight": 0.0 }, { "disease_id": "DOID:0080259", "name": "autosomal recessive spinocerebellar ataxia 25", "description": "An autosomal recessive cerebellar ataxia that has_material_basis_in homozygous mutation in the ATG5 gene on chromosome 6q21.", "url": "https://disease-ontology.org/term/DOID:0080259", "evidence": [ { "id": "0080259", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080259" } ], "weight": 0.0 }, { "disease_id": "DOID:0080547", "name": "metabolic dysfunction-associated steatohepatitis", "description": "A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.", "url": "https://disease-ontology.org/term/DOID:0080547", "evidence": [ { "id": "0080547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080547" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cellular response to potassium ion starvation", "id": "GO:0051365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051365", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "aggrephagy", "id": "GO:0035973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035973", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "Atg12-Atg5-Atg16 complex", "id": "GO:0034274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034274", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "vacuole-isolation membrane contact site", "id": "GO:0120095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120095", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "phagophore", "id": "GO:0061908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061908", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" }, { "name": "cargo receptor ligand activity", "id": "GO:0140355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140355", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12380-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Lys149", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of conjugation.", "evidence": [ { "database": "UniProtKB", "id": "Q12380", "url": "https://www.uniprot.org/uniprotkb/Q12380" }, { "database": "PubMed", "id": "9759731", "url": "https://glygen.org/publication/PubMed/9759731" } ] } ] } ], "record_id": "Q12380-1" }, { "uniprot_canonical_ac": "Q12396-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 444, "chemical_mass": 50947.0, "gene_names": "EMP46;EMP46", "protein_name": "Protein EMP46", "disease": [ { "disease_id": "DOID:0061042", "name": "autosomal dominant intellectual developmental disorder 69", "description": "An autosomal dominant intellectual developmental disorder characterized by developmental delay with variably impaired intellectual development that has_material_basis_in heterozygous mutation in the LMAN2L gene on chromosome 2q11.", "url": "https://disease-ontology.org/term/DOID:0061042", "evidence": [ { "id": "0061042", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061042" } ], "weight": 0.0 }, { "disease_id": "DOID:0081215", "name": "autosomal recessive intellectual developmental disorder 52", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the LMAN2L gene on chromosome 2q11.", "url": "https://disease-ontology.org/term/DOID:0081215", "evidence": [ { "id": "0081215", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081215" } ], "weight": 0.0 }, { "disease_id": "DOID:2211", "name": "factor XIII deficiency", "description": "A blood coagulation disease that is characterized by easy bleeding, has_symptom prolonged umbilical cord bleeding, epistaxis, bleeding of the gums, menorrhagia, recurrent miscarriages, abnormal scar formation and wound healing, and hemarthrosis, and has_material_basis_in autosomal recessive inheritance of mutation of the F13A1 or F13B gene, which encodes Factor XIII, formally known as fibrin stabilizing factor.", "url": "https://disease-ontology.org/term/DOID:2211", "evidence": [ { "id": "2211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2211" } ], "weight": 0.0 }, { "disease_id": "DOID:2216", "name": "factor V deficiency", "description": "", "url": "https://disease-ontology.org/term/DOID:2216", "evidence": [ { "id": "2216", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2216" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "pmid": "" }, { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12396-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Tyr177", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Impairs potassium-binding.", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" }, { "database": "PubMed", "id": "16439369", "url": "https://glygen.org/publication/PubMed/16439369" } ] } ] }, { "uniprot_canonical_ac": "Q12396-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Tyr429", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Impairs interaction with COP1, SEC21 and SEC23 and loss of endoplasmic reticulum exit.", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" }, { "database": "PubMed", "id": "12134087", "url": "https://glygen.org/publication/PubMed/12134087" } ] } ] }, { "uniprot_canonical_ac": "Q12396-1", "start_pos": "432", "end_pos": "432", "site_lbl": "Phe432", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Impairs interaction with COP1, SEC21 and SEC23 and loss of endoplasmic reticulum exit.", "evidence": [ { "database": "UniProtKB", "id": "Q12396", "url": "https://www.uniprot.org/uniprotkb/Q12396" }, { "database": "PubMed", "id": "12134087", "url": "https://glygen.org/publication/PubMed/12134087" } ] } ] } ], "record_id": "Q12396-1" }, { "uniprot_canonical_ac": "Q12425-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 185, "chemical_mass": 20877.0, "gene_names": "ISA2;ISA2;YP9499.22", "protein_name": "Iron-sulfur assembly protein 2", "disease": [ { "disease_id": "DOID:0080136", "name": "multiple mitochondrial dysfunctions syndrome 4", "description": "A multiple mitochondrial dysfunctions syndrome that is characterized by normal development for the first months of life, followed by progressive loss of motor and social skills with hypotonia, spasticity, and nystagmus, resulting in death in early childhood, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the iron-sulfur cluster assembly 2 gene on chromosome 14q24.", "url": "https://disease-ontology.org/term/DOID:0080136", "evidence": [ { "id": "0080136", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080136" } ], "weight": 0.0 } ], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "pmid": "" }, { "name": "[4Fe-4S] cluster assembly", "id": "GO:0044572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044572", "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "pmid": "" }, { "name": "biotin biosynthetic process", "id": "GO:0009102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009102", "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "pmid": "" } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q12425", "url": "https://www.uniprot.org/uniprotkb/Q12425" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q12425-1" }, { "uniprot_canonical_ac": "Q12440-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 853, "chemical_mass": 99978.0, "gene_names": "APC2;APC2;L3105;L3108;RSI1;TID2", "protein_name": "Anaphase-promoting complex subunit 2", "disease": [ { "disease_id": "DOID:12449", "name": "aplastic anemia", "description": "A normocytic anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow.", "url": "https://disease-ontology.org/term/DOID:12449", "evidence": [ { "id": "12449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12449" } ], "weight": 0.0 }, { "disease_id": "DOID:1405", "name": "primary angle-closure glaucoma", "description": "An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component.", "url": "https://disease-ontology.org/term/DOID:1405", "evidence": [ { "id": "1405", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1405" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:5386", "name": "lung adenoma", "description": "A lung benign neoplasm that derives_from glandular epithelial cells.", "url": "https://disease-ontology.org/term/DOID:5386", "evidence": [ { "id": "5386", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5386" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "pmid": "" }, { "name": "exit from mitosis", "id": "GO:0010458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010458", "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "pmid": "" }, { "name": "regulation of meiotic cell cycle", "id": "GO:0051445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051445", "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "pmid": "" }, { "name": "positive regulation of mitotic actomyosin contractile ring contraction", "id": "GO:1903473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903473", "evidence": [ { "database": "UniProtKB", "id": "Q12440", "url": "https://www.uniprot.org/uniprotkb/Q12440" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12440-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Ser434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004117", "url": "https://www.yeastgenome.org/locus/S000004117" }, { "database": "iPTMnet", "id": "Q12440", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12440" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12440-1", "start_pos": "768", "end_pos": "768", "site_lbl": "Ser768", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004117", "url": "https://www.yeastgenome.org/locus/S000004117" }, { "database": "iPTMnet", "id": "Q12440", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12440" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12440-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Tyr76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12440", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12440" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004117", "url": "https://www.yeastgenome.org/locus/S000004117" } ] } ] }, { "uniprot_canonical_ac": "Q12440-1", "start_pos": "837", "end_pos": "837", "site_lbl": "Tyr837", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004117", "url": "https://www.yeastgenome.org/locus/S000004117" }, { "database": "iPTMnet", "id": "Q12440", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12440" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12440-1", "start_pos": "842", "end_pos": "842", "site_lbl": "Ser842", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004117", "url": "https://www.yeastgenome.org/locus/S000004117" }, { "database": "iPTMnet", "id": "Q12440", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12440" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "Q12440-1" }, { "uniprot_canonical_ac": "Q12452-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12452", "url": "https://www.uniprot.org/uniprotkb/Q12452" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 347, "chemical_mass": 39725.0, "gene_names": "ERG27;ERG27", "protein_name": "3-keto-steroid reductase ERG27", "disease": [ { "disease_id": "DOID:11612", "name": "polycystic ovary syndrome", "description": "An ovarian dysfunction that is characterized by hyperandrogenism, polycystic ovaries, hirsutism, oligomenorrhea or amenorrhea, anovulation and excessive body weight.", "url": "https://disease-ontology.org/term/DOID:11612", "evidence": [ { "id": "11612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11612" } ], "weight": 0.0 }, { "disease_id": "DOID:1701", "name": "steroid inherited metabolic disorder", "description": "A lipid metabolism disorder that involves defects in steroid metabolism.", "url": "https://disease-ontology.org/term/DOID:1701", "evidence": [ { "id": "1701", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1701" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ergosterol biosynthetic process", "id": "GO:0006696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006696", "evidence": [ { "database": "UniProtKB", "id": "Q12452", "url": "https://www.uniprot.org/uniprotkb/Q12452" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q12452", "url": "https://www.uniprot.org/uniprotkb/Q12452" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q12452", "url": "https://www.uniprot.org/uniprotkb/Q12452" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "Q12452", "url": "https://www.uniprot.org/uniprotkb/Q12452" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q12452", "url": "https://www.uniprot.org/uniprotkb/Q12452" } ], "pmid": "" } ], "molecular_function": [ { "name": "3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity", "id": "GO:0000253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000253", "evidence": [ { "database": "UniProtKB", "id": "Q12452", "url": "https://www.uniprot.org/uniprotkb/Q12452" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12452-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Thr343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12452", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12452" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004090", "url": "https://www.yeastgenome.org/locus/S000004090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12452-1", "start_pos": "345", "end_pos": "345", "site_lbl": "Thr345", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12452", "url": "https://www.uniprot.org/uniprotkb/Q12452" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q12452", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12452" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004090", "url": "https://www.yeastgenome.org/locus/S000004090" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12452-1" }, { "uniprot_canonical_ac": "Q12466-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1186, "chemical_mass": 133576.0, "gene_names": "TCB1;TCB1;YOR3141c", "protein_name": "Tricalbin-1", "disease": [], "cellular_component": [ { "name": "nucleus-vacuole junction", "id": "GO:0071561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071561", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "cortical endoplasmic reticulum", "id": "GO:0032541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032541", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" } ], "biological_process": [ { "name": "endoplasmic reticulum membrane organization", "id": "GO:0090158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090158", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "regulation of phosphatidylinositol dephosphorylation", "id": "GO:0060304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060304", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "ER to Golgi ceramide transport", "id": "GO:0035621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035621", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane tethering", "id": "GO:0061817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061817", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12466-1", "start_pos": "1000", "end_pos": "1000", "site_lbl": "Ser1000", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12466", "url": "https://www.uniprot.org/uniprotkb/Q12466" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "1069", "end_pos": "1069", "site_lbl": "Ser1069", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "1135", "end_pos": "1135", "site_lbl": "Ser1135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "1146", "end_pos": "1146", "site_lbl": "Thr1146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "1147", "end_pos": "1147", "site_lbl": "Thr1147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "1169", "end_pos": "1169", "site_lbl": "Ser1169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Ser42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "654", "end_pos": "654", "site_lbl": "Thr654", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12466-1", "start_pos": "846", "end_pos": "846", "site_lbl": "Ser846", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005612", "url": "https://www.yeastgenome.org/locus/S000005612" }, { "database": "iPTMnet", "id": "Q12466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12466" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12466-1" }, { "uniprot_canonical_ac": "Q12472-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1770, "chemical_mass": 201965.0, "gene_names": "TY2B-DR1;YD9673.05c;YDRCTy2-1 POL", "protein_name": "Transposon Ty2-DR1 Gag-Pol polyprotein", "disease": [], "molecular_function": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "transposition", "id": "GO:0032196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032196", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" }, { "name": "viral translational frameshifting", "id": "GO:0075523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075523", "evidence": [ { "database": "UniProtKB", "id": "Q12472", "url": "https://www.uniprot.org/uniprotkb/Q12472" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12472-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12472", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12472" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] } ] } ], "record_id": "Q12472-1" }, { "uniprot_canonical_ac": "Q12476-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 344, "chemical_mass": 39344.0, "gene_names": "AIR2;AIR2", "protein_name": "Protein AIR2", "disease": [], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "TRAMP complex", "id": "GO:0031499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031499", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snoRNA catabolic process", "id": "GO:0071036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071036", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snRNA catabolic process", "id": "GO:0071037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071037", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent CUT catabolic process", "id": "GO:0071039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071039", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "nuclear mRNA surveillance of mRNA 3'-end processing", "id": "GO:0071031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071031", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "polyadenylation-dependent RNA catabolic process", "id": "GO:0043633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043633", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" }, { "name": "RNA fragment catabolic process", "id": "GO:0000292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000292", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12476-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Thr12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Thr15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Thr16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Ser199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12476", "url": "https://www.uniprot.org/uniprotkb/Q12476" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002334", "url": "https://www.yeastgenome.org/locus/S000002334" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12476-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12476" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "Q12476-1" }, { "uniprot_canonical_ac": "Q12483-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12483", "url": "https://www.uniprot.org/uniprotkb/Q12483" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 233, "chemical_mass": 26954.0, "gene_names": "SNF8;SNF8;VPL14;VPS22", "protein_name": "Vacuolar-sorting protein SNF8", "disease": [ { "disease_id": "DOID:0112202", "name": "developmental and epileptic encephalopathy", "description": "An electroclinical syndrome characterized by epileptiform activity and at least one other pathology that together contribute to cognitive and behavioral impairments including developmental delay or regression with onset anywhere from birth to adulthood.", "url": "https://disease-ontology.org/term/DOID:0112202", "evidence": [ { "id": "0112202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112202" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ESCRT II complex", "id": "GO:0000814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000814", "evidence": [ { "database": "UniProtKB", "id": "Q12483", "url": "https://www.uniprot.org/uniprotkb/Q12483" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043328", "evidence": [ { "database": "UniProtKB", "id": "Q12483", "url": "https://www.uniprot.org/uniprotkb/Q12483" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q12483", "url": "https://www.uniprot.org/uniprotkb/Q12483" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "Q12483", "url": "https://www.uniprot.org/uniprotkb/Q12483" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "Q12483", "url": "https://www.uniprot.org/uniprotkb/Q12483" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "Q12483", "url": "https://www.uniprot.org/uniprotkb/Q12483" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q12483", "url": "https://www.uniprot.org/uniprotkb/Q12483" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12483-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005923", "url": "https://www.yeastgenome.org/locus/S000005923" }, { "database": "iPTMnet", "id": "Q12483", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12483" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12483-1" }, { "uniprot_canonical_ac": "Q12498-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12498", "url": "https://www.uniprot.org/uniprotkb/Q12498" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 284, "chemical_mass": 32012.0, "gene_names": "PRM4;P2578;PRM4", "protein_name": "Pheromone-regulated membrane protein 4", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q12498", "url": "https://www.uniprot.org/uniprotkb/Q12498" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "Q12498", "url": "https://www.uniprot.org/uniprotkb/Q12498" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q12498-1" }, { "uniprot_canonical_ac": "Q12502-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 818, "chemical_mass": 89826.0, "gene_names": "LDB19;ART1;LDB19;O6152", "protein_name": "Protein LDB19", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:14525", "name": "Reye syndrome", "description": "A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.", "url": "https://disease-ontology.org/term/DOID:14525", "evidence": [ { "id": "14525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14525" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" }, { "name": "Golgi trans cisterna", "id": "GO:0000138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000138", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of receptor internalization", "id": "GO:0002092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002092", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" }, { "name": "cellular response to stress", "id": "GO:0033554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033554", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" }, { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12502-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 103, "start_aa": "Ser", "end_pos": 103, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser103", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 104, "start_aa": "Ser", "end_pos": 104, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser104", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 106, "start_aa": "Ser", "end_pos": 106, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser106", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "22118465", "url": "https://glygen.org/publication/PubMed/22118465" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 108, "start_aa": "Ser", "end_pos": 108, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser108", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Thr109", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 109, "start_aa": "Thr", "end_pos": 109, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr109", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 110, "start_aa": "Ser", "end_pos": 110, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser110", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 113, "start_aa": "Ser", "end_pos": 113, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser113", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 115, "start_aa": "Ser", "end_pos": 115, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser115", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 117, "start_aa": "Ser", "end_pos": 117, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser117", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 118, "start_aa": "Ser", "end_pos": 118, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser118", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 120, "start_aa": "Ser", "end_pos": 120, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser120", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 122, "start_aa": "Ser", "end_pos": 122, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser122", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 124, "start_aa": "Ser", "end_pos": 124, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser124", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Thr126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 126, "start_aa": "Thr", "end_pos": 126, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr126", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Thr267", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 267, "start_aa": "Thr", "end_pos": 267, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr267", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "751", "end_pos": "751", "site_lbl": "Thr751", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 751, "start_aa": "Thr", "end_pos": 751, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr751", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "755", "end_pos": "755", "site_lbl": "Thr755", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 755, "start_aa": "Thr", "end_pos": 755, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr755", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "763", "end_pos": "763", "site_lbl": "Ser763", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 763, "start_aa": "Ser", "end_pos": 763, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser763", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "31618110", "url": "https://glygen.org/publication/PubMed/31618110" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "764", "end_pos": "764", "site_lbl": "Ser764", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 764, "start_aa": "Ser", "end_pos": 764, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser764", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "31618110", "url": "https://glygen.org/publication/PubMed/31618110" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "765", "end_pos": "765", "site_lbl": "Ser765", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 765, "start_aa": "Ser", "end_pos": 765, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser765", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "31618110", "url": "https://glygen.org/publication/PubMed/31618110" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "798", "end_pos": "798", "site_lbl": "Ser798", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 798, "start_aa": "Ser", "end_pos": 798, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser798", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q12502", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q12502" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Ser238", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "31618110", "url": "https://glygen.org/publication/PubMed/31618110" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Ser240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Ser241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Ser244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Thr245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "384", "end_pos": "384", "site_lbl": "Ser384", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Ser466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Ser599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "607", "end_pos": "607", "site_lbl": "Thr607", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "619", "end_pos": "619", "site_lbl": "Thr619", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "22118465", "url": "https://glygen.org/publication/PubMed/22118465" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "623", "end_pos": "623", "site_lbl": "Ser623", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "22118465", "url": "https://glygen.org/publication/PubMed/22118465" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Ser626", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "629", "end_pos": "629", "site_lbl": "Ser629", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "709", "end_pos": "709", "site_lbl": "Ser709", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "22118465", "url": "https://glygen.org/publication/PubMed/22118465" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "710", "end_pos": "710", "site_lbl": "Thr710", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "714", "end_pos": "714", "site_lbl": "Ser714", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "722", "end_pos": "722", "site_lbl": "Ser722", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "729", "end_pos": "729", "site_lbl": "Tyr729", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "768", "end_pos": "768", "site_lbl": "Ser768", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "31618110", "url": "https://glygen.org/publication/PubMed/31618110" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "770", "end_pos": "770", "site_lbl": "Thr770", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "31618110", "url": "https://glygen.org/publication/PubMed/31618110" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "771", "end_pos": "771", "site_lbl": "Thr771", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "31618110", "url": "https://glygen.org/publication/PubMed/31618110" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "774", "end_pos": "774", "site_lbl": "Ser774", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "31618110", "url": "https://glygen.org/publication/PubMed/31618110" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "779", "end_pos": "779", "site_lbl": "Ser779", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "782", "end_pos": "782", "site_lbl": "Ser782", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "795", "end_pos": "795", "site_lbl": "Thr795", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "799", "end_pos": "799", "site_lbl": "Thr799", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "22118465", "url": "https://glygen.org/publication/PubMed/22118465" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "808", "end_pos": "808", "site_lbl": "Ser808", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "22118465", "url": "https://glygen.org/publication/PubMed/22118465" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Thr83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Thr84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "92", "end_pos": "92", "site_lbl": "Ser92", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "31618110", "url": "https://glygen.org/publication/PubMed/31618110" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Thr93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12502", "url": "https://www.uniprot.org/uniprotkb/Q12502" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "31618110", "url": "https://glygen.org/publication/PubMed/31618110" }, { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "Q12502-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005849", "url": "https://www.yeastgenome.org/locus/S000005849" }, { "database": "iPTMnet", "id": "Q12502", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12502" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "Q12502-1" }, { "uniprot_canonical_ac": "Q12508-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 421, "chemical_mass": 49169.0, "gene_names": "RMD5;GID2;RMD5;YD9320A.05c", "protein_name": "E3 ubiquitin-protein ligase RMD5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" }, { "name": "negative regulation of gluconeogenesis", "id": "GO:0045721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045721", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12508-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Cys379", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes FBP1 ubiquitination and degradation.", "evidence": [ { "database": "UniProtKB", "id": "Q12508", "url": "https://www.uniprot.org/uniprotkb/Q12508" }, { "database": "PubMed", "id": "18508925", "url": "https://glygen.org/publication/PubMed/18508925" } ] } ] } ], "record_id": "Q12508-1" }, { "uniprot_canonical_ac": "Q12517-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 231, "chemical_mass": 26266.0, "gene_names": "DCP1;DCP1;MRT2", "protein_name": "mRNA-decapping enzyme subunit 1", "disease": [], "biological_process": [ { "name": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0000290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000290", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" }, { "name": "deadenylation-independent decapping of nuclear-transcribed mRNA", "id": "GO:0031087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031087", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" }, { "name": "cytoplasmic side of membrane", "id": "GO:0098562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098562", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" }, { "name": "RNA decapping complex", "id": "GO:0098745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098745", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12517-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005509", "url": "https://www.yeastgenome.org/locus/S000005509" }, { "database": "iPTMnet", "id": "Q12517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Tyr118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005509", "url": "https://www.yeastgenome.org/locus/S000005509" }, { "database": "iPTMnet", "id": "Q12517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12517" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005509", "url": "https://www.yeastgenome.org/locus/S000005509" }, { "database": "iPTMnet", "id": "Q12517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12517" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005509", "url": "https://www.yeastgenome.org/locus/S000005509" }, { "database": "iPTMnet", "id": "Q12517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12517" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005509", "url": "https://www.yeastgenome.org/locus/S000005509" }, { "database": "iPTMnet", "id": "Q12517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005509", "url": "https://www.yeastgenome.org/locus/S000005509" }, { "database": "iPTMnet", "id": "Q12517", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Gly156", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In DCP1-1; strong loss of mRNA decapping activity.", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" }, { "database": "PubMed", "id": "10101156", "url": "https://glygen.org/publication/PubMed/10101156" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Trp204", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "In DCP1-33; partial loss of mRNA decapping activity.", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" }, { "database": "PubMed", "id": "10101156", "url": "https://glygen.org/publication/PubMed/10101156" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Leu217", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Strong loss of mRNA-decapping activity; when associated with A-37; A-38 and A-221.", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" }, { "database": "PubMed", "id": "14758354", "url": "https://glygen.org/publication/PubMed/14758354" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Leu221", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Strong loss of mRNA-decapping activity; when associated with A-37; A-38 and A-217.", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" }, { "database": "PubMed", "id": "14758354", "url": "https://glygen.org/publication/PubMed/14758354" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Tyr47", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "In DCP1-32; partial loss of mRNA decapping activity.", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" }, { "database": "PubMed", "id": "10101156", "url": "https://glygen.org/publication/PubMed/10101156" } ] }, { "sequence_org": "Y", "sequence_mut": "F", "comment": "In DCP1-35; partial loss of mRNA decapping activity.", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" }, { "database": "PubMed", "id": "10101156", "url": "https://glygen.org/publication/PubMed/10101156" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Trp56", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "In DCP1-31; partial loss of mRNA decapping activity.", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" }, { "database": "PubMed", "id": "14758354", "url": "https://glygen.org/publication/PubMed/14758354" }, { "database": "PubMed", "id": "10101156", "url": "https://glygen.org/publication/PubMed/10101156" }, { "database": "PubMed", "id": "8757137", "url": "https://glygen.org/publication/PubMed/8757137" } ] } ] }, { "uniprot_canonical_ac": "Q12517-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Arg70", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "In DCP1-33; strong loss of mRNA decapping activity.", "evidence": [ { "database": "UniProtKB", "id": "Q12517", "url": "https://www.uniprot.org/uniprotkb/Q12517" }, { "database": "PubMed", "id": "14758354", "url": "https://glygen.org/publication/PubMed/14758354" }, { "database": "PubMed", "id": "10101156", "url": "https://glygen.org/publication/PubMed/10101156" } ] } ] } ], "record_id": "Q12517-1" }, { "uniprot_canonical_ac": "Q12522-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 245, "chemical_mass": 26458.0, "gene_names": "TIF6;CDC95;LPZ15C;TIF6", "protein_name": "Eukaryotic translation initiation factor 6", "disease": [ { "disease_id": "DOID:0060479", "name": "Shwachman-Diamond syndrome", "description": "A syndrome characterized by exocrine pancreatic insufficiency, bone marrow failure and skeletal abnormalities.", "url": "https://disease-ontology.org/term/DOID:0060479", "evidence": [ { "id": "0060479", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060479" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "cytosolic ribosome assembly", "id": "GO:0042256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042256", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000466", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "assembly of large subunit precursor of preribosome", "id": "GO:1902626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902626", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" }, { "name": "ribosomal large subunit binding", "id": "GO:0043023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043023", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12522-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" }, { "database": "iPTMnet", "id": "Q12522", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12522" }, { "database": "PubMed", "id": "18256024", "url": "https://glygen.org/publication/PubMed/18256024" }, { "database": "PubMed", "id": "12917340", "url": "https://glygen.org/publication/PubMed/12917340" } ] } ] }, { "uniprot_canonical_ac": "Q12522-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" }, { "database": "iPTMnet", "id": "Q12522", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12522" }, { "database": "PubMed", "id": "18256024", "url": "https://glygen.org/publication/PubMed/18256024" }, { "database": "PubMed", "id": "12917340", "url": "https://glygen.org/publication/PubMed/12917340" } ] } ] }, { "uniprot_canonical_ac": "Q12522-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12522", "url": "https://www.uniprot.org/uniprotkb/Q12522" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q12522", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12522" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006220", "url": "https://www.yeastgenome.org/locus/S000006220" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12522-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12522", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12522" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006220", "url": "https://www.yeastgenome.org/locus/S000006220" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12522-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Thr74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006220", "url": "https://www.yeastgenome.org/locus/S000006220" }, { "database": "iPTMnet", "id": "Q12522", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12522" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12522-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006220", "url": "https://www.yeastgenome.org/locus/S000006220" }, { "database": "iPTMnet", "id": "Q12522", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12522" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12522-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006220", "url": "https://www.yeastgenome.org/locus/S000006220" }, { "database": "iPTMnet", "id": "Q12522", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12522" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12522-1" }, { "uniprot_canonical_ac": "Q12734-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1121, "chemical_mass": 124849.0, "gene_names": "CSR2;ART8;CSR2;MRG19;YP9367.10", "protein_name": "Transcription factor CSR2", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:14525", "name": "Reye syndrome", "description": "A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.", "url": "https://disease-ontology.org/term/DOID:14525", "evidence": [ { "id": "14525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14525" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" } ], "pmid": "" }, { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q12734-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Tyr130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Ser327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Thr43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "525", "end_pos": "525", "site_lbl": "Ser525", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "528", "end_pos": "528", "site_lbl": "Ser528", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Ser544", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Thr72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "963", "end_pos": "963", "site_lbl": "Ser963", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "983", "end_pos": "983", "site_lbl": "Ser983", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ] }, { "uniprot_canonical_ac": "Q12734-1", "start_pos": "987", "end_pos": "987", "site_lbl": "Ser987", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q12734", "url": "https://www.uniprot.org/uniprotkb/Q12734" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q12734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12734" }, { "database": "SGD", "id": "S000006234", "url": "https://www.yeastgenome.org/locus/S000006234" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q12734-1" }, { "uniprot_canonical_ac": "Q3E7Y6-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q3E7Y6", "url": "https://www.uniprot.org/uniprotkb/Q3E7Y6" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 73, "chemical_mass": 8547.0, "gene_names": "NBL1;NBL1", "protein_name": "N-terminal-borealin-like protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q3E7Y6", "url": "https://www.uniprot.org/uniprotkb/Q3E7Y6" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q3E7Y6", "url": "https://www.uniprot.org/uniprotkb/Q3E7Y6" } ], "pmid": "" }, { "name": "chromosome passenger complex", "id": "GO:0032133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032133", "evidence": [ { "database": "UniProtKB", "id": "Q3E7Y6", "url": "https://www.uniprot.org/uniprotkb/Q3E7Y6" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q3E7Y6", "url": "https://www.uniprot.org/uniprotkb/Q3E7Y6" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle spindle assembly checkpoint", "id": "GO:0090267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090267", "evidence": [ { "database": "UniProtKB", "id": "Q3E7Y6", "url": "https://www.uniprot.org/uniprotkb/Q3E7Y6" } ], "pmid": "" }, { "name": "sister chromatid biorientation", "id": "GO:0031134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031134", "evidence": [ { "database": "UniProtKB", "id": "Q3E7Y6", "url": "https://www.uniprot.org/uniprotkb/Q3E7Y6" } ], "pmid": "" }, { "name": "attachment of meiotic spindle microtubules to kinetochore", "id": "GO:0051316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051316", "evidence": [ { "database": "UniProtKB", "id": "Q3E7Y6", "url": "https://www.uniprot.org/uniprotkb/Q3E7Y6" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q3E7Y6", "url": "https://www.uniprot.org/uniprotkb/Q3E7Y6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q3E7Y6-1" }, { "uniprot_canonical_ac": "Q92317-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 146, "chemical_mass": 16650.0, "gene_names": "NCB2;NCB2;YDR1", "protein_name": "Negative cofactor 2 complex subunit beta", "disease": [], "biological_process": [ { "name": "negative regulation of RNA polymerase II transcription preinitiation complex assembly", "id": "GO:0017055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017055", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase III", "id": "GO:0016480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016480", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "regulation of RNA polymerase II transcription preinitiation complex assembly", "id": "GO:0045898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045898", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" }, { "name": "negative cofactor 2 complex", "id": "GO:0017054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017054", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q92317-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002805", "url": "https://www.yeastgenome.org/locus/S000002805" }, { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q92317-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P15790-1", "kinase_gene_name": "CKA1", "evidence": [ { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "12502746", "url": "https://glygen.org/publication/PubMed/12502746" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "kinase_uniprot_canonical_ac": "P19454-1", "kinase_gene_name": "CKA2", "evidence": [ { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "12502746", "url": "https://glygen.org/publication/PubMed/12502746" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "kinase_uniprot_canonical_ac": "P38930-1", "kinase_gene_name": "CKB2", "evidence": [ { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "12502746", "url": "https://glygen.org/publication/PubMed/12502746" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "kinase_uniprot_canonical_ac": "P43639-1", "kinase_gene_name": "CKB1", "evidence": [ { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "12502746", "url": "https://glygen.org/publication/PubMed/12502746" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002805", "url": "https://www.yeastgenome.org/locus/S000002805" }, { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q92317-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002805", "url": "https://www.yeastgenome.org/locus/S000002805" }, { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "Q92317-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002805", "url": "https://www.yeastgenome.org/locus/S000002805" }, { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "Q92317-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000002805", "url": "https://www.yeastgenome.org/locus/S000002805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "Q92317-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "SGD", "id": "S000002805", "url": "https://www.yeastgenome.org/locus/S000002805" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q92317-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q92317", "url": "https://www.uniprot.org/uniprotkb/Q92317" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000002805", "url": "https://www.yeastgenome.org/locus/S000002805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q92317-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002805", "url": "https://www.yeastgenome.org/locus/S000002805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "Q92317-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q92317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q92317" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002805", "url": "https://www.yeastgenome.org/locus/S000002805" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] } ], "record_id": "Q92317-1" }, { "uniprot_canonical_ac": "Q99181-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q99181", "url": "https://www.uniprot.org/uniprotkb/Q99181" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 213, "chemical_mass": 24503.0, "gene_names": "HSH49;HSH49;O6142", "protein_name": "Protein HSH49", "disease": [ { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:5768", "name": "Nager acrofacial dysostosis", "description": "An acrofacial dysostosis characterized by underdeveloped cheek bones, very small lower jaw, cleft palate, defects in the middle ear, absent eyelashes, and a notch in the lower eyelids called a coloboma, in children.", "url": "https://disease-ontology.org/term/DOID:5768", "evidence": [ { "id": "5768", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5768" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q99181", "url": "https://www.uniprot.org/uniprotkb/Q99181" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q99181", "url": "https://www.uniprot.org/uniprotkb/Q99181" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "Q99181", "url": "https://www.uniprot.org/uniprotkb/Q99181" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "Q99181", "url": "https://www.uniprot.org/uniprotkb/Q99181" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q99181", "url": "https://www.uniprot.org/uniprotkb/Q99181" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "Q99181", "url": "https://www.uniprot.org/uniprotkb/Q99181" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q99181-1" }, { "uniprot_canonical_ac": "Q99207-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 810, "chemical_mass": 94302.0, "gene_names": "NOP14;D1566;NOP14;UTP2", "protein_name": "Nucleolar complex protein 14", "disease": [ { "disease_id": "DOID:12215", "name": "oligohydramnios", "description": "A placenta disease that is characterized by a deficiency of amniotic fluid sometimes resulting in an embryonic defect through adherence between embryo and amnion.", "url": "https://disease-ontology.org/term/DOID:12215", "evidence": [ { "id": "12215", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12215" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "Noc4p-Nop14p complex", "id": "GO:0030692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030692", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" } ], "biological_process": [ { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" } ], "molecular_function": [ { "name": "U3 snoRNA binding", "id": "GO:0034511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034511", "evidence": [ { "database": "UniProtKB", "id": "Q99207", "url": "https://www.uniprot.org/uniprotkb/Q99207" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q99207-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002307", "url": "https://www.yeastgenome.org/locus/S000002307" }, { "database": "iPTMnet", "id": "Q99207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99207" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q99207-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Ser368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002307", "url": "https://www.yeastgenome.org/locus/S000002307" }, { "database": "iPTMnet", "id": "Q99207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99207" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q99207-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Ser463", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002307", "url": "https://www.yeastgenome.org/locus/S000002307" }, { "database": "iPTMnet", "id": "Q99207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99207" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q99207-1", "start_pos": "774", "end_pos": "774", "site_lbl": "Ser774", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q99207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99207" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "Q99207-1", "start_pos": "775", "end_pos": "775", "site_lbl": "Ser775", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q99207", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99207" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] } ], "record_id": "Q99207-1" }, { "uniprot_canonical_ac": "Q99260-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 215, "chemical_mass": 24413.0, "gene_names": "YPT6;L8479.11;YPT6", "protein_name": "GTP-binding protein YPT6", "disease": [ { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "protein-containing complex localization", "id": "GO:0031503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031503", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q99260", "url": "https://www.uniprot.org/uniprotkb/Q99260" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q99260-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004252", "url": "https://www.yeastgenome.org/locus/S000004252" }, { "database": "iPTMnet", "id": "Q99260", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99260" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q99260-1" }, { "uniprot_canonical_ac": "Q99325-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q99325", "url": "https://www.uniprot.org/uniprotkb/Q99325" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 256, "chemical_mass": 29693.0, "gene_names": "ATG40;ATG40;O3536", "protein_name": "Autophagy-related protein 40", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q99325", "url": "https://www.uniprot.org/uniprotkb/Q99325" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q99325", "url": "https://www.uniprot.org/uniprotkb/Q99325" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "Q99325", "url": "https://www.uniprot.org/uniprotkb/Q99325" } ], "pmid": "" }, { "name": "cortical endoplasmic reticulum", "id": "GO:0032541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032541", "evidence": [ { "database": "UniProtKB", "id": "Q99325", "url": "https://www.uniprot.org/uniprotkb/Q99325" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q99325", "url": "https://www.uniprot.org/uniprotkb/Q99325" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "Q99325", "url": "https://www.uniprot.org/uniprotkb/Q99325" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "Q99325", "url": "https://www.uniprot.org/uniprotkb/Q99325" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q99325-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Tyr242", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Impairs interaction with ATG8 and decreases subsequent reticulophagy; when associated with A-245.", "evidence": [ { "database": "UniProtKB", "id": "Q99325", "url": "https://www.uniprot.org/uniprotkb/Q99325" }, { "database": "PubMed", "id": "26040717", "url": "https://glygen.org/publication/PubMed/26040717" } ] } ] }, { "uniprot_canonical_ac": "Q99325-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Met245", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "A", "comment": "Impairs interaction with ATG8 and decreases subsequent reticulophagy; when associated with A-245.", "evidence": [ { "database": "UniProtKB", "id": "Q99325", "url": "https://www.uniprot.org/uniprotkb/Q99325" }, { "database": "PubMed", "id": "26040717", "url": "https://glygen.org/publication/PubMed/26040717" } ] } ] } ], "record_id": "Q99325-1" }, { "uniprot_canonical_ac": "Q99359-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q99359", "url": "https://www.uniprot.org/uniprotkb/Q99359" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 647, "chemical_mass": 74722.0, "gene_names": "RAD61;PZB647;RAD61;WPL1", "protein_name": "Protein RAD61", "disease": [], "biological_process": [ { "name": "negative regulation of chromosome condensation", "id": "GO:1902340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902340", "evidence": [ { "database": "UniProtKB", "id": "Q99359", "url": "https://www.uniprot.org/uniprotkb/Q99359" } ], "pmid": "" }, { "name": "meiotic DNA double-strand break formation", "id": "GO:0042138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042138", "evidence": [ { "database": "UniProtKB", "id": "Q99359", "url": "https://www.uniprot.org/uniprotkb/Q99359" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "Q99359", "url": "https://www.uniprot.org/uniprotkb/Q99359" } ], "pmid": "" }, { "name": "chromatin looping", "id": "GO:0140588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140588", "evidence": [ { "database": "UniProtKB", "id": "Q99359", "url": "https://www.uniprot.org/uniprotkb/Q99359" } ], "pmid": "" }, { "name": "negative regulation of maintenance of mitotic sister chromatid cohesion", "id": "GO:0034183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034183", "evidence": [ { "database": "UniProtKB", "id": "Q99359", "url": "https://www.uniprot.org/uniprotkb/Q99359" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q99359", "url": "https://www.uniprot.org/uniprotkb/Q99359" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q99359-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002421", "url": "https://www.yeastgenome.org/locus/S000002421" }, { "database": "iPTMnet", "id": "Q99359", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99359" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q99359-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Ser244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002421", "url": "https://www.yeastgenome.org/locus/S000002421" }, { "database": "iPTMnet", "id": "Q99359", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99359" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q99359-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Ser416", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002421", "url": "https://www.yeastgenome.org/locus/S000002421" }, { "database": "iPTMnet", "id": "Q99359", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99359" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q99359-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "Q99359", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99359" }, { "database": "PubMed", "id": "30605471", "url": "https://glygen.org/publication/PubMed/30605471" } ] } ] }, { "uniprot_canonical_ac": "Q99359-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002421", "url": "https://www.yeastgenome.org/locus/S000002421" }, { "database": "iPTMnet", "id": "Q99359", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99359" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "Q99359-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002421", "url": "https://www.yeastgenome.org/locus/S000002421" }, { "database": "iPTMnet", "id": "Q99359", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99359" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "Q99359-1" }, { "uniprot_canonical_ac": "Q9URQ3-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q9URQ3", "url": "https://www.uniprot.org/uniprotkb/Q9URQ3" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 322, "chemical_mass": 37107.0, "gene_names": "TAD3;TAD3", "protein_name": "tRNA-specific adenosine-34 deaminase regulatory subunit TAD3", "disease": [ { "disease_id": "DOID:0081099", "name": "neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies", "description": "An autosomal recessive intellectual developmental disorder that is characterized by global developmental delay with delayed walking, impaired intellectual development, and speech delay apparent from infancy or early childhood and that has_material_basis_in homozygous mutation in the ADAT3 gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0081099", "evidence": [ { "id": "0081099", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081099" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9URQ3", "url": "https://www.uniprot.org/uniprotkb/Q9URQ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9URQ3", "url": "https://www.uniprot.org/uniprotkb/Q9URQ3" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9URQ3", "url": "https://www.uniprot.org/uniprotkb/Q9URQ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA-specific adenosine deaminase activity", "id": "GO:0008251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008251", "evidence": [ { "database": "UniProtKB", "id": "Q9URQ3", "url": "https://www.uniprot.org/uniprotkb/Q9URQ3" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA wobble adenosine to inosine editing", "id": "GO:0002100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002100", "evidence": [ { "database": "UniProtKB", "id": "Q9URQ3", "url": "https://www.uniprot.org/uniprotkb/Q9URQ3" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "Q9URQ3", "url": "https://www.uniprot.org/uniprotkb/Q9URQ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9URQ3-1" }, { "uniprot_canonical_ac": "O13539-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "O13539", "url": "https://www.uniprot.org/uniprotkb/O13539" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 261, "chemical_mass": 30299.0, "gene_names": "THP2;THP2", "protein_name": "THO complex subunit THP2", "disease": [], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "O13539", "url": "https://www.uniprot.org/uniprotkb/O13539" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "O13539", "url": "https://www.uniprot.org/uniprotkb/O13539" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "O13539", "url": "https://www.uniprot.org/uniprotkb/O13539" } ], "pmid": "" }, { "name": "cellular response to azide", "id": "GO:0097185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097185", "evidence": [ { "database": "UniProtKB", "id": "O13539", "url": "https://www.uniprot.org/uniprotkb/O13539" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "O13539", "url": "https://www.uniprot.org/uniprotkb/O13539" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "O13539", "url": "https://www.uniprot.org/uniprotkb/O13539" } ], "pmid": "" } ], "cellular_component": [ { "name": "THO complex part of transcription export complex", "id": "GO:0000445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000445", "evidence": [ { "database": "UniProtKB", "id": "O13539", "url": "https://www.uniprot.org/uniprotkb/O13539" } ], "pmid": "" }, { "name": "nucleoplasmic THO complex", "id": "GO:0000446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000446", "evidence": [ { "database": "UniProtKB", "id": "O13539", "url": "https://www.uniprot.org/uniprotkb/O13539" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "O13539-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Ser247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001210", "url": "https://www.yeastgenome.org/locus/S000001210" }, { "database": "iPTMnet", "id": "O13539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O13539" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "O13539-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Ser249", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "O13539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O13539" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001210", "url": "https://www.yeastgenome.org/locus/S000001210" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "O13539-1" }, { "uniprot_canonical_ac": "P10963-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P10963", "url": "https://www.uniprot.org/uniprotkb/P10963" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 549, "chemical_mass": 60983.0, "gene_names": "PCK1;JPM2;PCK1;PEPC;PPC1", "protein_name": "Phosphoenolpyruvate carboxykinase (ATP)", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P10963", "url": "https://www.uniprot.org/uniprotkb/P10963" } ], "pmid": "" }, { "name": "phosphoenolpyruvate carboxykinase (ATP) activity", "id": "GO:0004612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004612", "evidence": [ { "database": "UniProtKB", "id": "P10963", "url": "https://www.uniprot.org/uniprotkb/P10963" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P10963", "url": "https://www.uniprot.org/uniprotkb/P10963" } ], "pmid": "" } ], "biological_process": [ { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "P10963", "url": "https://www.uniprot.org/uniprotkb/P10963" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P10963-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Ser330", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001805", "url": "https://www.yeastgenome.org/locus/S000001805" }, { "database": "iPTMnet", "id": "P10963", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10963" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P10963-1" }, { "uniprot_canonical_ac": "P23248-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23248", "url": "https://www.uniprot.org/uniprotkb/P23248" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 255, "chemical_mass": 28812.0, "gene_names": "RPS1B;PLC2;RP10B;RPS10B;RPS1B", "protein_name": "Small ribosomal subunit protein eS1B", "disease": [ { "disease_id": "DOID:0060036", "name": "intrinsic cardiomyopathy", "description": "A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause.", "url": "https://disease-ontology.org/term/DOID:0060036", "evidence": [ { "id": "0060036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060036" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P23248", "url": "https://www.uniprot.org/uniprotkb/P23248" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P23248", "url": "https://www.uniprot.org/uniprotkb/P23248" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P23248", "url": "https://www.uniprot.org/uniprotkb/P23248" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P23248", "url": "https://www.uniprot.org/uniprotkb/P23248" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P23248", "url": "https://www.uniprot.org/uniprotkb/P23248" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "P23248", "url": "https://www.uniprot.org/uniprotkb/P23248" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P23248", "url": "https://www.uniprot.org/uniprotkb/P23248" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P23248-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Ser154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ser159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Ser169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Thr185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Ser236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P23248", "url": "https://www.uniprot.org/uniprotkb/P23248" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Thr254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P23248", "url": "https://www.uniprot.org/uniprotkb/P23248" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] } ] }, { "uniprot_canonical_ac": "P23248-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P23248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23248" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000004528", "url": "https://www.yeastgenome.org/locus/S000004528" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P23248-1" }, { "uniprot_canonical_ac": "P23624-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23624", "url": "https://www.uniprot.org/uniprotkb/P23624" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 291, "chemical_mass": 33295.0, "gene_names": "SPO13;SPO13", "protein_name": "Meiosis-specific protein SPO13", "disease": [], "biological_process": [ { "name": "protein localization to chromosome, centromeric region", "id": "GO:0071459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071459", "evidence": [ { "database": "UniProtKB", "id": "P23624", "url": "https://www.uniprot.org/uniprotkb/P23624" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P23624", "url": "https://www.uniprot.org/uniprotkb/P23624" } ], "pmid": "" }, { "name": "positive regulation of sister chromatid cohesion", "id": "GO:0045876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045876", "evidence": [ { "database": "UniProtKB", "id": "P23624", "url": "https://www.uniprot.org/uniprotkb/P23624" } ], "pmid": "" }, { "name": "meiotic sister chromatid cohesion", "id": "GO:0051177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051177", "evidence": [ { "database": "UniProtKB", "id": "P23624", "url": "https://www.uniprot.org/uniprotkb/P23624" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P23624", "url": "https://www.uniprot.org/uniprotkb/P23624" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P23624", "url": "https://www.uniprot.org/uniprotkb/P23624" } ], "pmid": "" }, { "name": "meiotic spindle", "id": "GO:0072687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072687", "evidence": [ { "database": "UniProtKB", "id": "P23624", "url": "https://www.uniprot.org/uniprotkb/P23624" } ], "pmid": "" }, { "name": "condensed chromosome, centromeric region", "id": "GO:0000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000779", "evidence": [ { "database": "UniProtKB", "id": "P23624", "url": "https://www.uniprot.org/uniprotkb/P23624" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "P23624", "url": "https://www.uniprot.org/uniprotkb/P23624" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P23624-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Thr221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P23624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23624" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P23624-1" }, { "uniprot_canonical_ac": "P28004-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28004", "url": "https://www.uniprot.org/uniprotkb/P28004" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 379, "chemical_mass": 42483.0, "gene_names": "PRP45;FUN20;PRP45", "protein_name": "Pre-mRNA-processing protein 45", "disease": [ { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P28004", "url": "https://www.uniprot.org/uniprotkb/P28004" } ], "pmid": "" }, { "name": "post-mRNA release spliceosomal complex", "id": "GO:0071014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071014", "evidence": [ { "database": "UniProtKB", "id": "P28004", "url": "https://www.uniprot.org/uniprotkb/P28004" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "P28004", "url": "https://www.uniprot.org/uniprotkb/P28004" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "P28004", "url": "https://www.uniprot.org/uniprotkb/P28004" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P28004", "url": "https://www.uniprot.org/uniprotkb/P28004" } ], "pmid": "" }, { "name": "generation of catalytic spliceosome for second transesterification step", "id": "GO:0000350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000350", "evidence": [ { "database": "UniProtKB", "id": "P28004", "url": "https://www.uniprot.org/uniprotkb/P28004" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28004-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000030", "url": "https://www.yeastgenome.org/locus/S000000030" }, { "database": "iPTMnet", "id": "P28004", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28004" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28004-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Ser374", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000030", "url": "https://www.yeastgenome.org/locus/S000000030" }, { "database": "iPTMnet", "id": "P28004", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28004" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28004-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000030", "url": "https://www.yeastgenome.org/locus/S000000030" }, { "database": "iPTMnet", "id": "P28004", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28004" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P28004-1" }, { "uniprot_canonical_ac": "P28005-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 173, "chemical_mass": 19574.0, "gene_names": "POP5;FUN53;POP5", "protein_name": "Ribonuclease P/MRP protein subunit POP5", "disease": [], "molecular_function": [ { "name": "ribonuclease MRP activity", "id": "GO:0000171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000171", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" }, { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" }, { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, RNase MRP-dependent", "id": "GO:0000294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000294", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" }, { "name": "intronic box C/D snoRNA processing", "id": "GO:0034965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034965", "evidence": [ { "database": "UniProtKB", "id": "P28005", "url": "https://www.uniprot.org/uniprotkb/P28005" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P28005-1" }, { "uniprot_canonical_ac": "P28007-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28007", "url": "https://www.uniprot.org/uniprotkb/P28007" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 205, "chemical_mass": 21480.0, "gene_names": "GAR1;GAR1", "protein_name": "H/ACA ribonucleoprotein complex subunit GAR1", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P28007", "url": "https://www.uniprot.org/uniprotkb/P28007" } ], "pmid": "" }, { "name": "box H/ACA snoRNP complex", "id": "GO:0031429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031429", "evidence": [ { "database": "UniProtKB", "id": "P28007", "url": "https://www.uniprot.org/uniprotkb/P28007" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P28007", "url": "https://www.uniprot.org/uniprotkb/P28007" } ], "pmid": "" }, { "name": "box H/ACA snoRNA binding", "id": "GO:0034513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034513", "evidence": [ { "database": "UniProtKB", "id": "P28007", "url": "https://www.uniprot.org/uniprotkb/P28007" } ], "pmid": "" } ], "biological_process": [ { "name": "snRNA pseudouridine synthesis", "id": "GO:0031120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031120", "evidence": [ { "database": "UniProtKB", "id": "P28007", "url": "https://www.uniprot.org/uniprotkb/P28007" } ], "pmid": "" }, { "name": "snoRNA guided rRNA pseudouridine synthesis", "id": "GO:0000454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000454", "evidence": [ { "database": "UniProtKB", "id": "P28007", "url": "https://www.uniprot.org/uniprotkb/P28007" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28007-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001131", "url": "https://www.yeastgenome.org/locus/S000001131" }, { "database": "iPTMnet", "id": "P28007", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28007" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P28007-1" }, { "uniprot_canonical_ac": "P28240-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 557, "chemical_mass": 62409.0, "gene_names": "ICL1;ICL1", "protein_name": "Isocitrate lyase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" } ], "pmid": "" }, { "name": "glyoxylate cycle", "id": "GO:0006097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006097", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" } ], "pmid": "" }, { "name": "isocitrate lyase activity", "id": "GO:0004451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004451", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" } ], "pmid": "" }, { "name": "methylisocitrate lyase activity", "id": "GO:0046421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046421", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28240-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Thr53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes short-term enzyme inactivation by glucose addition.", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" }, { "database": "PubMed", "id": "8641464", "url": "https://glygen.org/publication/PubMed/8641464" } ] } ] }, { "uniprot_canonical_ac": "P28240-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Lys216", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Reduces activity by 45%; when associated with L-220.", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" }, { "database": "PubMed", "id": "8923733", "url": "https://glygen.org/publication/PubMed/8923733" } ] } ] }, { "uniprot_canonical_ac": "P28240-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Met220", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "L", "comment": "Reduces activity by 45%; when associated with R-216.", "evidence": [ { "database": "UniProtKB", "id": "P28240", "url": "https://www.uniprot.org/uniprotkb/P28240" }, { "database": "PubMed", "id": "8923733", "url": "https://glygen.org/publication/PubMed/8923733" } ] } ] } ], "record_id": "P28240-1" }, { "uniprot_canonical_ac": "P28241-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 369, "chemical_mass": 39739.0, "gene_names": "IDH2;IDH2;O3326;YOR3326W", "protein_name": "Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial", "disease": [ { "disease_id": "DOID:0050709", "name": "early infantile epileptic encephalopathy", "description": "A neonatal period electroclinical syndrome that is characterized by tonic spasms and partial seizures.", "url": "https://disease-ontology.org/term/DOID:0050709", "evidence": [ { "id": "0050709", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050709" } ], "weight": 0.0 }, { "disease_id": "DOID:0112147", "name": "retinitis pigmentosa 90", "description": "A retinitis pigmentosa characterized by onset in the first decade of life of night blindness that has_material_basis_in homozygous or compound heterozygous mutation in the IDH3A gene on chromosome 15q25.1.", "url": "https://disease-ontology.org/term/DOID:0112147", "evidence": [ { "id": "0112147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112147" } ], "weight": 0.0 }, { "disease_id": "DOID:439", "name": "neuromuscular junction disease", "description": "A neuromuscular disease that is characterized by the disfunction of conduction through the neuromuscular junction.", "url": "https://disease-ontology.org/term/DOID:439", "evidence": [ { "id": "439", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:439" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "pmid": "" }, { "name": "isocitrate dehydrogenase (NAD+) activity", "id": "GO:0004449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004449", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "pmid": "" }, { "name": "isocitrate dehydrogenase complex (NAD+)", "id": "GO:0045242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045242", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "pmid": "" }, { "name": "isocitrate metabolic process", "id": "GO:0006102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006102", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "pmid": "" }, { "name": "glutamate biosynthetic process", "id": "GO:0006537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006537", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28241-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 5, "start_aa": "Thr", "end_pos": 5, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr5", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P28241", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P28241" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Thr105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Thr117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" }, { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Thr153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" }, { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Thr280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" }, { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" }, { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Thr327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Thr349", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P28241", "url": "https://www.uniprot.org/uniprotkb/P28241" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Thr355", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" }, { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Ser360", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28241-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Thr362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005662", "url": "https://www.yeastgenome.org/locus/S000005662" }, { "database": "iPTMnet", "id": "P28241", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28241" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P28241-1" }, { "uniprot_canonical_ac": "P28263-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 218, "chemical_mass": 24633.0, "gene_names": "UBC8;GID3;UBC8", "protein_name": "Ubiquitin-conjugating enzyme E2-24 kDa", "disease": [ { "disease_id": "DOID:934", "name": "viral infectious disease", "description": "A disease by infectious agent that results in infection, has_material_basis_in Viruses.", "url": "https://disease-ontology.org/term/DOID:934", "evidence": [ { "id": "934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:934" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" }, { "name": "negative regulation of gluconeogenesis", "id": "GO:0045721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045721", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" }, { "name": "mitochondrial outer membrane translocase complex assembly", "id": "GO:0070096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070096", "evidence": [ { "database": "UniProtKB", "id": "P28263", "url": "https://www.uniprot.org/uniprotkb/P28263" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28263-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000738", "url": "https://www.yeastgenome.org/locus/S000000738" }, { "database": "iPTMnet", "id": "P28263", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28263" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P28263-1" }, { "uniprot_canonical_ac": "P28272-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28272", "url": "https://www.uniprot.org/uniprotkb/P28272" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 314, "chemical_mass": 34801.0, "gene_names": "URA1;URA1", "protein_name": "Dihydroorotate dehydrogenase (fumarate)", "disease": [ { "disease_id": "DOID:0111259", "name": "postaxial acrofacial dysostosis", "description": "A syndrome characterized by severe micrognathia, cleft lip and/or palate, hypoplasia or aplasia of the postaxial elements of the limbs, coloboma of the eyelids, cup-shaped ears, and supernumerary nipples that has_material_basis_in homozygous or compound heterozygous mutation in DHODH on 16q22.2.", "url": "https://disease-ontology.org/term/DOID:0111259", "evidence": [ { "id": "0111259", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111259" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P28272", "url": "https://www.uniprot.org/uniprotkb/P28272" } ], "pmid": "" } ], "molecular_function": [ { "name": "dihydroorotate dehydrogenase activity", "id": "GO:0004152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004152", "evidence": [ { "database": "UniProtKB", "id": "P28272", "url": "https://www.uniprot.org/uniprotkb/P28272" } ], "pmid": "" }, { "name": "dihydroorotate dehydrogenase (fumarate) activity", "id": "GO:1990663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990663", "evidence": [ { "database": "UniProtKB", "id": "P28272", "url": "https://www.uniprot.org/uniprotkb/P28272" } ], "pmid": "" } ], "biological_process": [ { "name": "'de novo' pyrimidine nucleobase biosynthetic process", "id": "GO:0006207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006207", "evidence": [ { "database": "UniProtKB", "id": "P28272", "url": "https://www.uniprot.org/uniprotkb/P28272" } ], "pmid": "" }, { "name": "'de novo' UMP biosynthetic process", "id": "GO:0044205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044205", "evidence": [ { "database": "UniProtKB", "id": "P28272", "url": "https://www.uniprot.org/uniprotkb/P28272" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28272-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001699", "url": "https://www.yeastgenome.org/locus/S000001699" }, { "database": "iPTMnet", "id": "P28272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28272-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Thr29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001699", "url": "https://www.yeastgenome.org/locus/S000001699" }, { "database": "iPTMnet", "id": "P28272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28272-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28272" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P28272-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Ser303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001699", "url": "https://www.yeastgenome.org/locus/S000001699" }, { "database": "iPTMnet", "id": "P28272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28272" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28272-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Thr49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001699", "url": "https://www.yeastgenome.org/locus/S000001699" }, { "database": "iPTMnet", "id": "P28272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28272" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28272-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001699", "url": "https://www.yeastgenome.org/locus/S000001699" }, { "database": "iPTMnet", "id": "P28272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28272-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Thr50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001699", "url": "https://www.yeastgenome.org/locus/S000001699" }, { "database": "iPTMnet", "id": "P28272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P28272-1" }, { "uniprot_canonical_ac": "P28274-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 579, "chemical_mass": 64710.0, "gene_names": "URA7;URA7;YBL0410", "protein_name": "CTP synthase 1", "disease": [ { "disease_id": "DOID:0050625", "name": "biliary tract benign neoplasm", "description": "A hepatobiliary benign neoplasm located_in the biliary tract.", "url": "https://disease-ontology.org/term/DOID:0050625", "evidence": [ { "id": "0050625", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050625" } ], "weight": 0.0 }, { "disease_id": "DOID:0111938", "name": "immunodeficiency 24", "description": "A severe combined immunodeficiency characterized by impaired proliferation of activated T and B cells in response to antigen receptor-mediated activation that has_material_basis_in homozygous or compound heterozygous mutation in the CTPS1 gene on chromosome 1p34.2.", "url": "https://disease-ontology.org/term/DOID:0111938", "evidence": [ { "id": "0111938", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111938" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "pmid": "" }, { "name": "CTP synthase activity", "id": "GO:0003883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003883", "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "pmid": "" }, { "name": "cytoophidium", "id": "GO:0097268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097268", "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "pmid": "" }, { "name": "'de novo' CTP biosynthetic process", "id": "GO:0044210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044210", "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "pmid": "" }, { "name": "CTP biosynthetic process", "id": "GO:0006241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006241", "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "pmid": "" }, { "name": "pyrimidine nucleobase biosynthetic process", "id": "GO:0019856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019856", "evidence": [ { "database": "UniProtKB", "id": "P28274", "url": "https://www.uniprot.org/uniprotkb/P28274" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28274-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000135", "url": "https://www.yeastgenome.org/locus/S000000135" }, { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000135", "url": "https://www.yeastgenome.org/locus/S000000135" }, { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Thr293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Ser330", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "12670958", "url": "https://glygen.org/publication/PubMed/12670958" }, { "database": "SGD", "id": "S000000135", "url": "https://www.yeastgenome.org/locus/S000000135" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "12670958", "url": "https://glygen.org/publication/PubMed/12670958" }, { "database": "SGD", "id": "S000000135", "url": "https://www.yeastgenome.org/locus/S000000135" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "12670958", "url": "https://glygen.org/publication/PubMed/12670958" }, { "database": "SGD", "id": "S000000135", "url": "https://www.yeastgenome.org/locus/S000000135" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Tyr3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Ser424", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "10393561", "url": "https://glygen.org/publication/PubMed/10393561" }, { "database": "PubMed", "id": "12709422", "url": "https://glygen.org/publication/PubMed/12709422" }, { "database": "SGD", "id": "S000000135", "url": "https://www.yeastgenome.org/locus/S000000135" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Ser426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000135", "url": "https://www.yeastgenome.org/locus/S000000135" }, { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "454", "end_pos": "454", "site_lbl": "Ser454", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "12670958", "url": "https://glygen.org/publication/PubMed/12670958" }, { "database": "SGD", "id": "S000000135", "url": "https://www.yeastgenome.org/locus/S000000135" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Ser481", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000135", "url": "https://www.yeastgenome.org/locus/S000000135" }, { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28274-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28274" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000135", "url": "https://www.yeastgenome.org/locus/S000000135" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P28274-1" }, { "uniprot_canonical_ac": "P28319-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28319", "url": "https://www.uniprot.org/uniprotkb/P28319" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 239, "chemical_mass": 24268.0, "gene_names": "CWP1;CWP1;YJU1;YKL443", "protein_name": "Cell wall protein CWP1", "disease": [], "molecular_function": [ { "name": "structural constituent of cell wall", "id": "GO:0005199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005199", "evidence": [ { "database": "UniProtKB", "id": "P28319", "url": "https://www.uniprot.org/uniprotkb/P28319" } ], "pmid": "" } ], "cellular_component": [ { "name": "cellular birth scar", "id": "GO:0071597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071597", "evidence": [ { "database": "UniProtKB", "id": "P28319", "url": "https://www.uniprot.org/uniprotkb/P28319" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P28319", "url": "https://www.uniprot.org/uniprotkb/P28319" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P28319", "url": "https://www.uniprot.org/uniprotkb/P28319" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P28319", "url": "https://www.uniprot.org/uniprotkb/P28319" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P28319", "url": "https://www.uniprot.org/uniprotkb/P28319" } ], "pmid": "" } ], "biological_process": [ { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P28319", "url": "https://www.uniprot.org/uniprotkb/P28319" } ], "pmid": "" }, { "name": "ascospore-type prospore membrane formation", "id": "GO:0032120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032120", "evidence": [ { "database": "UniProtKB", "id": "P28319", "url": "https://www.uniprot.org/uniprotkb/P28319" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28319-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Tyr111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001579", "url": "https://www.yeastgenome.org/locus/S000001579" }, { "database": "iPTMnet", "id": "P28319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28319" }, { "database": "PubMed", "id": "31870255", "url": "https://glygen.org/publication/PubMed/31870255" } ] } ] }, { "uniprot_canonical_ac": "P28319-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001579", "url": "https://www.yeastgenome.org/locus/S000001579" }, { "database": "iPTMnet", "id": "P28319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28319" }, { "database": "PubMed", "id": "31870255", "url": "https://glygen.org/publication/PubMed/31870255" } ] } ] }, { "uniprot_canonical_ac": "P28319-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001579", "url": "https://www.yeastgenome.org/locus/S000001579" }, { "database": "iPTMnet", "id": "P28319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28319" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28319-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001579", "url": "https://www.yeastgenome.org/locus/S000001579" }, { "database": "iPTMnet", "id": "P28319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28319" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28319-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Tyr74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001579", "url": "https://www.yeastgenome.org/locus/S000001579" }, { "database": "iPTMnet", "id": "P28319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28319" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] } ] }, { "uniprot_canonical_ac": "P28319-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001579", "url": "https://www.yeastgenome.org/locus/S000001579" }, { "database": "iPTMnet", "id": "P28319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28319" }, { "database": "PubMed", "id": "31870255", "url": "https://glygen.org/publication/PubMed/31870255" } ] } ] }, { "uniprot_canonical_ac": "P28319-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001579", "url": "https://www.yeastgenome.org/locus/S000001579" }, { "database": "iPTMnet", "id": "P28319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28319" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P28319-1" }, { "uniprot_canonical_ac": "P28320-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28320", "url": "https://www.uniprot.org/uniprotkb/P28320" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 278, "chemical_mass": 32312.0, "gene_names": "YJU2;CWC16;YJU2;YKL442", "protein_name": "Splicing factor YJU2", "disease": [], "biological_process": [ { "name": "generation of catalytic spliceosome for first transesterification step", "id": "GO:0000349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000349", "evidence": [ { "database": "UniProtKB", "id": "P28320", "url": "https://www.uniprot.org/uniprotkb/P28320" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P28320", "url": "https://www.uniprot.org/uniprotkb/P28320" } ], "pmid": "" }, { "name": "generation of catalytic spliceosome for second transesterification step", "id": "GO:0000350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000350", "evidence": [ { "database": "UniProtKB", "id": "P28320", "url": "https://www.uniprot.org/uniprotkb/P28320" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "P28320", "url": "https://www.uniprot.org/uniprotkb/P28320" } ], "pmid": "" } ], "molecular_function": [ { "name": "U2 snRNA binding", "id": "GO:0030620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030620", "evidence": [ { "database": "UniProtKB", "id": "P28320", "url": "https://www.uniprot.org/uniprotkb/P28320" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P28320", "url": "https://www.uniprot.org/uniprotkb/P28320" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P28320", "url": "https://www.uniprot.org/uniprotkb/P28320" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "P28320", "url": "https://www.uniprot.org/uniprotkb/P28320" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "P28320", "url": "https://www.uniprot.org/uniprotkb/P28320" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P28320-1" }, { "uniprot_canonical_ac": "P28321-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 313, "chemical_mass": 35563.0, "gene_names": "YJU3;YJU3;YKL441", "protein_name": "Monoglyceride lipase", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" } ], "biological_process": [ { "name": "triglyceride metabolic process", "id": "GO:0006641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006641", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" }, { "name": "triglyceride catabolic process", "id": "GO:0019433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019433", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" } ], "molecular_function": [ { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "P28321", "url": "https://www.uniprot.org/uniprotkb/P28321" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28321-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Tyr226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001577", "url": "https://www.yeastgenome.org/locus/S000001577" }, { "database": "iPTMnet", "id": "P28321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28321-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Tyr232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001577", "url": "https://www.yeastgenome.org/locus/S000001577" }, { "database": "iPTMnet", "id": "P28321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28321-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Thr81", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001577", "url": "https://www.yeastgenome.org/locus/S000001577" }, { "database": "iPTMnet", "id": "P28321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28321-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001577", "url": "https://www.yeastgenome.org/locus/S000001577" }, { "database": "iPTMnet", "id": "P28321", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28321" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P28321-1" }, { "uniprot_canonical_ac": "P28496-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 418, "chemical_mass": 48992.0, "gene_names": "LAC1;DGT1;LAC1;YKL156", "protein_name": "Ceramide synthase LAC1", "disease": [ { "disease_id": "DOID:0060718", "name": "autosomal recessive congenital ichthyosis 9", "description": "An autosomal recessive congenital ichthyosis characterized by fine erythrodermic scales, palmoplantar hyperlinearity, thick orthohyperkeratosis, hypergranulosis, moderate acanthosis and mild alopecia that has_material_basis_in homozygous mutation in the CERS3 gene on chromosome 15q26.", "url": "https://disease-ontology.org/term/DOID:0060718", "evidence": [ { "id": "0060718", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060718" } ], "weight": 0.0 }, { "disease_id": "DOID:0111451", "name": "progressive myoclonus epilepsy 8", "description": "A progressive myoclonus epilepsy characterized by childhood to adolescent-onset of action myoclonus, generalized tonic-clonic seizures, and slowly progressive, moderate to severe cognitive impairment that has_material_basis_in homozygous or compound heterozygous mutation in CERS1 on chromosome 19p13.11.", "url": "https://disease-ontology.org/term/DOID:0111451", "evidence": [ { "id": "0111451", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111451" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" } ], "pmid": "" }, { "name": "acyl-CoA ceramide synthase complex", "id": "GO:0061576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061576", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" } ], "pmid": "" } ], "molecular_function": [ { "name": "sphingosine N-acyltransferase activity", "id": "GO:0050291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050291", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28496-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Asn103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 103, "start_aa": "Asn", "end_pos": 103, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn103", "evidence": [ { "id": "P28496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28496#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "iPTMnet", "id": "P28496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28496" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001491", "url": "https://www.yeastgenome.org/locus/S000001491" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "iPTMnet", "id": "P28496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28496" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001491", "url": "https://www.yeastgenome.org/locus/S000001491" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001491", "url": "https://www.yeastgenome.org/locus/S000001491" }, { "database": "iPTMnet", "id": "P28496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28496" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Ser395", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001491", "url": "https://www.yeastgenome.org/locus/S000001491" }, { "database": "iPTMnet", "id": "P28496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28496" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Ser397", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001491", "url": "https://www.yeastgenome.org/locus/S000001491" }, { "database": "iPTMnet", "id": "P28496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28496" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Thr407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001491", "url": "https://www.yeastgenome.org/locus/S000001491" }, { "database": "iPTMnet", "id": "P28496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28496" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001491", "url": "https://www.yeastgenome.org/locus/S000001491" }, { "database": "iPTMnet", "id": "P28496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28496" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001491", "url": "https://www.yeastgenome.org/locus/S000001491" }, { "database": "iPTMnet", "id": "P28496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28496" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Arg172", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Abolishes the enzymatic activity of the ceramide synthase complex. Does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with A-293, A-296, A-318 and A-381.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Does not affect the enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Gln227", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "About 80% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Trp231", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "About 85% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "255", "end_pos": "255", "site_lbl": "His255", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes the enzymatic activity of the LAC1-LIP1 complex; alone or when associated with A-256. Does not catalyze the reaction between hexacosanoyl-CoA and fumonisin B1; when associated with A-256.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" }, { "database": "PubMed", "id": "38964337", "url": "https://glygen.org/publication/PubMed/38964337" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "256", "end_pos": "256", "site_lbl": "His256", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes the enzymatic activity of the LAC1-LIP1 complex; alone or when associated with A-255. Does not catalyze the reaction between hexacosanoyl-CoA and fumonisin B1; when associated with A-255.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" }, { "database": "PubMed", "id": "38964337", "url": "https://glygen.org/publication/PubMed/38964337" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "F", "comment": "Abolishes the enzymatic activity of the ceramide synthase complex and does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with F-266, F-275, F-353 and F-375.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "F", "comment": "Abolishes the enzymatic activity of the ceramide synthase complex and does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with F-265, F-275, F-353 and F-375.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Phe269", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "About 75% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Phe271", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "More than 90% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Met274", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "A", "comment": "About 80% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Gly275", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "F", "comment": "Abolishes the enzymatic activity of the ceramide synthase complex and does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with F-265, F-266, F-353 and F-375.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Tyr279", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "About 90% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Met282", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "A", "comment": "About 60% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Asp283", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduces the enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Asp286", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes the enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Lys293", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "About 80% loss in enzymatic activity of the LAC1-LIP1 complex. Does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with A-172, A-296, A-318 and A-381.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Asn296", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "About 60% loss in enzymatic activity of the LAC1-LIP1 complex. Does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with A-172, A-293, A-318 and A-381.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Arg318", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Abolishes the enzymatic activity of the LAC1-LIP1 complex. Does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with A-172, A-293, A-296 and A-381.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Leu341", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "About 90% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Phe343", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "More than 90% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Tyr348", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "More than 90% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ile352", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "A", "comment": "About 60% loss in enzymatic activity of the LAC1-LIP1 complex.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "37953642", "url": "https://glygen.org/publication/PubMed/37953642" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "F", "comment": "Abolishes the enzymatic activity of the ceramide synthase complex and does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with F-265, F-266, F-275 and F-375.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Ile375", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "F", "comment": "Abolishes the enzymatic activity of the ceramide synthase complex and does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with F-265, F-266, F-275 and F-353.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Arg381", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Abolishes the enzymatic activity of the ceramide synthase complex. Does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with A-172, A-293, A-296 and A-318.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Lys389", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Reduces the in vitro activity of LAC1-LIP1 complex in the presence of ACB1, increases the levels of phytosphingosine in vivo and does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with A-392.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] }, { "uniprot_canonical_ac": "P28496-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Arg392", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces the in vitro activity of LAC1-LIP1 complex in the presence of ACB1, increases the levels of phytosphingosine in vivo and does not rescue the growth defect of LAC1-LAG1 double deletion mutant; when associated with A-389.", "evidence": [ { "database": "UniProtKB", "id": "P28496", "url": "https://www.uniprot.org/uniprotkb/P28496" }, { "database": "PubMed", "id": "39528796", "url": "https://glygen.org/publication/PubMed/39528796" } ] } ] } ], "record_id": "P28496-1" }, { "uniprot_canonical_ac": "P28627-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 190, "chemical_mass": 21433.0, "gene_names": "IMP1;IMP1;PET2858;YM9375.20C", "protein_name": "Mitochondrial inner membrane protease subunit 1", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane peptidase complex", "id": "GO:0042720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042720", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" } ], "pmid": "" } ], "molecular_function": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" } ], "pmid": "" }, { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing involved in protein targeting to mitochondrion", "id": "GO:0006627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006627", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" } ], "pmid": "" }, { "name": "signal peptide processing", "id": "GO:0006465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006465", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28627-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Gly130", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "Abolishes processing of CYB2 and COX2 and presence of SOM1 in the IMP complex.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "15118906", "url": "https://glygen.org/publication/PubMed/15118906" } ] } ] }, { "uniprot_canonical_ac": "P28627-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Asp131", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "Reduces enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Reduces enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] }, { "sequence_org": "D", "sequence_mut": "Y", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] } ] }, { "uniprot_canonical_ac": "P28627-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Asp138", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] } ] }, { "uniprot_canonical_ac": "P28627-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] }, { "sequence_org": "S", "sequence_mut": "T", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] } ] }, { "uniprot_canonical_ac": "P28627-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Lys84", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "H", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] } ] }, { "uniprot_canonical_ac": "P28627-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Arg85", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "10608835", "url": "https://glygen.org/publication/PubMed/10608835" } ] } ] }, { "uniprot_canonical_ac": "P28627-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Gly88", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In pet ts2858; temperature-sensitive; abolishes processing of CYB2 and presence of SOM1 in the IMP complex.", "evidence": [ { "database": "UniProtKB", "id": "P28627", "url": "https://www.uniprot.org/uniprotkb/P28627" }, { "database": "PubMed", "id": "1886606", "url": "https://glygen.org/publication/PubMed/1886606" }, { "database": "PubMed", "id": "15118906", "url": "https://glygen.org/publication/PubMed/15118906" } ] } ] } ], "record_id": "P28627-1" }, { "uniprot_canonical_ac": "P28708-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 518, "chemical_mass": 58956.0, "gene_names": "PRR1;PRR1;YKL516", "protein_name": "Serine/threonine-protein kinase PRR1", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" } ], "pmid": "" }, { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" } ], "pmid": "" }, { "name": "negative regulation of conjugation with cellular fusion", "id": "GO:0031138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031138", "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28708-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001599", "url": "https://www.yeastgenome.org/locus/S000001599" }, { "database": "iPTMnet", "id": "P28708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28708" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28708-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Ser132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P28708", "url": "https://www.uniprot.org/uniprotkb/P28708" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P28708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28708" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001599", "url": "https://www.yeastgenome.org/locus/S000001599" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28708-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28708" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001599", "url": "https://www.yeastgenome.org/locus/S000001599" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28708-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Thr13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001599", "url": "https://www.yeastgenome.org/locus/S000001599" }, { "database": "iPTMnet", "id": "P28708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28708" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28708-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Ser250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001599", "url": "https://www.yeastgenome.org/locus/S000001599" }, { "database": "iPTMnet", "id": "P28708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28708" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P28708-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Ser255", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001599", "url": "https://www.yeastgenome.org/locus/S000001599" }, { "database": "iPTMnet", "id": "P28708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28708" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P28708-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001599", "url": "https://www.yeastgenome.org/locus/S000001599" }, { "database": "iPTMnet", "id": "P28708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28708" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28708-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Thr79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001599", "url": "https://www.yeastgenome.org/locus/S000001599" }, { "database": "iPTMnet", "id": "P28708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28708" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28708-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001599", "url": "https://www.yeastgenome.org/locus/S000001599" }, { "database": "iPTMnet", "id": "P28708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28708" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28708-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001599", "url": "https://www.yeastgenome.org/locus/S000001599" }, { "database": "iPTMnet", "id": "P28708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28708" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P28708-1" }, { "uniprot_canonical_ac": "P28742-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1111, "chemical_mass": 125795.0, "gene_names": "KIP1;CIN9;KIP1;YBL0504;YBL0521", "protein_name": "Kinesin-like protein KIP1", "disease": [ { "disease_id": "DOID:0060349", "name": "microcephaly with or without chorioretinopathy, lymphedema, or mental retardation", "description": "A syndrome characterized by variable expression of microcephaly, ocular disorders including chorioretinopathy, congenital lymphedema of the lower limbs, and mild to moderate intellectual disability.", "url": "https://disease-ontology.org/term/DOID:0060349", "evidence": [ { "id": "0060349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060349" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "mitotic spindle polar microtubule", "id": "GO:1990537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990537", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "microtubule depolymerization", "id": "GO:0007019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007019", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "mitotic spindle elongation", "id": "GO:0000022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000022", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "spindle elongation", "id": "GO:0051231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051231", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "centromere clustering", "id": "GO:0098653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098653", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "initial mitotic spindle pole body separation", "id": "GO:0000073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000073", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" }, { "name": "2-micrometer plasmid partitioning", "id": "GO:0030543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030543", "evidence": [ { "database": "UniProtKB", "id": "P28742", "url": "https://www.uniprot.org/uniprotkb/P28742" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28742-1", "start_pos": "1037", "end_pos": "1037", "site_lbl": "Ser1037", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "20463882", "url": "https://glygen.org/publication/PubMed/20463882" }, { "database": "SGD", "id": "S000000159", "url": "https://www.yeastgenome.org/locus/S000000159" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "1040", "end_pos": "1040", "site_lbl": "Thr1040", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "20463882", "url": "https://glygen.org/publication/PubMed/20463882" }, { "database": "SGD", "id": "S000000159", "url": "https://www.yeastgenome.org/locus/S000000159" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "1060", "end_pos": "1060", "site_lbl": "Ser1060", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000159", "url": "https://www.yeastgenome.org/locus/S000000159" }, { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "20463882", "url": "https://glygen.org/publication/PubMed/20463882" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "1068", "end_pos": "1068", "site_lbl": "Thr1068", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000159", "url": "https://www.yeastgenome.org/locus/S000000159" }, { "database": "PubMed", "id": "20463882", "url": "https://glygen.org/publication/PubMed/20463882" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "1088", "end_pos": "1088", "site_lbl": "Thr1088", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000159", "url": "https://www.yeastgenome.org/locus/S000000159" }, { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "20463882", "url": "https://glygen.org/publication/PubMed/20463882" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "1098", "end_pos": "1098", "site_lbl": "Thr1098", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000159", "url": "https://www.yeastgenome.org/locus/S000000159" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Ser213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000159", "url": "https://www.yeastgenome.org/locus/S000000159" }, { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "20463882", "url": "https://glygen.org/publication/PubMed/20463882" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "547", "end_pos": "547", "site_lbl": "Ser547", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000159", "url": "https://www.yeastgenome.org/locus/S000000159" }, { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "802", "end_pos": "802", "site_lbl": "Ser802", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000159", "url": "https://www.yeastgenome.org/locus/S000000159" }, { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "20463882", "url": "https://glygen.org/publication/PubMed/20463882" } ] } ] }, { "uniprot_canonical_ac": "P28742-1", "start_pos": "952", "end_pos": "952", "site_lbl": "Ser952", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000159", "url": "https://www.yeastgenome.org/locus/S000000159" }, { "database": "iPTMnet", "id": "P28742", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28742" }, { "database": "PubMed", "id": "20463882", "url": "https://glygen.org/publication/PubMed/20463882" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P28742-1" }, { "uniprot_canonical_ac": "P28743-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 706, "chemical_mass": 78378.0, "gene_names": "KIP2;KIP2;P2581", "protein_name": "Kinesin-like protein KIP2", "disease": [ { "disease_id": "DOID:0070283", "name": "primary autosomal recessive microcephaly 13", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the CENPE gene on chromosome 4q24.", "url": "https://disease-ontology.org/term/DOID:0070283", "evidence": [ { "id": "0070283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070283" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cortical microtubule plus-end", "id": "GO:1903754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903754", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule polymerization", "id": "GO:0046785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046785", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "nuclear migration along microtubule", "id": "GO:0030473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030473", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" }, { "name": "microtubule plus end polymerase", "id": "GO:0061863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061863", "evidence": [ { "database": "UniProtKB", "id": "P28743", "url": "https://www.uniprot.org/uniprotkb/P28743" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28743-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Ser531", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 531, "start_aa": "Ser", "end_pos": 531, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser531", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P28743", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P28743" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Ser271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Thr275", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "26395399", "url": "https://glygen.org/publication/PubMed/26395399" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Ser286", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "26395399", "url": "https://glygen.org/publication/PubMed/26395399" }, { "database": "PubMed", "id": "31490122", "url": "https://glygen.org/publication/PubMed/31490122" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "697", "end_pos": "697", "site_lbl": "Ser697", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Ser86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Ser88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28743-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Ser93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28743", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28743" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006076", "url": "https://www.yeastgenome.org/locus/S000006076" } ] } ] } ], "record_id": "P28743-1" }, { "uniprot_canonical_ac": "P28795-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28795", "url": "https://www.uniprot.org/uniprotkb/P28795" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 441, "chemical_mass": 50676.0, "gene_names": "PEX3;D9798.15;PAS3;PEX3", "protein_name": "Peroxisomal biogenesis factor 3", "disease": [ { "disease_id": "DOID:0080484", "name": "peroxisome biogenesis disorder 10A", "description": "A Zellweger syndrome that has_material_basis_in homozygous mutation in the PEX3 gene on chromosome 6q24.", "url": "https://disease-ontology.org/term/DOID:0080484", "evidence": [ { "id": "0080484", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080484" } ], "weight": 0.0 }, { "disease_id": "DOID:0081440", "name": "Peroxisome biogenesis disorder 10B", "description": "A peroxisomal biogenesis disorder that is characterized by the overlapping phenotypes of neonatal adrenoleukodystrophy and infantile Refsum disease and that has_material_basis_in compound heterozygous mutation in the PEX3 gene on chromosome 6q24.", "url": "https://disease-ontology.org/term/DOID:0081440", "evidence": [ { "id": "0081440", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081440" } ], "weight": 0.0 }, { "disease_id": "DOID:905", "name": "Zellweger syndrome", "description": "A peroxisomal biogenesis disorder that is characterized by severe neurologic dysfunction, craniofacial abnormalities, and liver dysfunction, and biochemically by the absence of peroxisome and that has_material_basis_in autosomal recessive inheritance of a mutation in the peroxisome biogenesis factor (PEX) genes.", "url": "https://disease-ontology.org/term/DOID:905", "evidence": [ { "id": "905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:905" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P28795", "url": "https://www.uniprot.org/uniprotkb/P28795" } ], "pmid": "" }, { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "P28795", "url": "https://www.uniprot.org/uniprotkb/P28795" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P28795", "url": "https://www.uniprot.org/uniprotkb/P28795" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P28795", "url": "https://www.uniprot.org/uniprotkb/P28795" } ], "pmid": "" } ], "biological_process": [ { "name": "ER-dependent peroxisome organization", "id": "GO:0032581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032581", "evidence": [ { "database": "UniProtKB", "id": "P28795", "url": "https://www.uniprot.org/uniprotkb/P28795" } ], "pmid": "" }, { "name": "protein import into peroxisome membrane", "id": "GO:0045046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045046", "evidence": [ { "database": "UniProtKB", "id": "P28795", "url": "https://www.uniprot.org/uniprotkb/P28795" } ], "pmid": "" }, { "name": "peroxisome inheritance", "id": "GO:0045033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045033", "evidence": [ { "database": "UniProtKB", "id": "P28795", "url": "https://www.uniprot.org/uniprotkb/P28795" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28795-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28795" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002737", "url": "https://www.yeastgenome.org/locus/S000002737" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28795-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002737", "url": "https://www.yeastgenome.org/locus/S000002737" }, { "database": "iPTMnet", "id": "P28795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28795" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28795-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28795" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002737", "url": "https://www.yeastgenome.org/locus/S000002737" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28795-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P28795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28795" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000002737", "url": "https://www.yeastgenome.org/locus/S000002737" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28795-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002737", "url": "https://www.yeastgenome.org/locus/S000002737" }, { "database": "iPTMnet", "id": "P28795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28795" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P28795-1" }, { "uniprot_canonical_ac": "P28817-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28817", "url": "https://www.uniprot.org/uniprotkb/P28817" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 500, "chemical_mass": 56288.0, "gene_names": "EHD3;EHD3;MRP5;YD9673.08C;mS47", "protein_name": "Small ribosomal subunit protein mS47", "disease": [ { "disease_id": "DOID:0060949", "name": "3-hydroxyisobutryl-CoA hydrolase deficiency", "description": "An amino acid metabolic disorder characterized by severely delayed psychomotor development, neurodegeneration, increased lactic acid, and brain lesions in the basal ganglia that has_material_basis_in homozygous or compound heterozygous mutation in the HIBCH gene on chromosome 2q32.", "url": "https://disease-ontology.org/term/DOID:0060949", "evidence": [ { "id": "0060949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060949" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "3-hydroxyisobutyryl-CoA hydrolase activity", "id": "GO:0003860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003860", "evidence": [ { "database": "UniProtKB", "id": "P28817", "url": "https://www.uniprot.org/uniprotkb/P28817" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P28817", "url": "https://www.uniprot.org/uniprotkb/P28817" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "P28817", "url": "https://www.uniprot.org/uniprotkb/P28817" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P28817", "url": "https://www.uniprot.org/uniprotkb/P28817" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P28817", "url": "https://www.uniprot.org/uniprotkb/P28817" } ], "pmid": "" } ], "biological_process": [ { "name": "L-valine catabolic process", "id": "GO:0006574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006574", "evidence": [ { "database": "UniProtKB", "id": "P28817", "url": "https://www.uniprot.org/uniprotkb/P28817" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "P28817", "url": "https://www.uniprot.org/uniprotkb/P28817" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28817-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Thr163", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 163, "start_aa": "Thr", "end_pos": 163, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr163", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P28817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P28817" } ] } ] }, { "uniprot_canonical_ac": "P28817-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Thr166", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 166, "start_aa": "Thr", "end_pos": 166, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr166", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P28817", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P28817" } ] } ] }, { "uniprot_canonical_ac": "P28817-1", "start_pos": "326", "end_pos": "326", "site_lbl": "Thr326", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P28817", "url": "https://www.uniprot.org/uniprotkb/P28817" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P28817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28817" }, { "database": "SGD", "id": "S000002443", "url": "https://www.yeastgenome.org/locus/S000002443" } ] } ] } ], "record_id": "P28817-1" }, { "uniprot_canonical_ac": "P28834-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 360, "chemical_mass": 39324.0, "gene_names": "IDH1;IDH1;N2690", "protein_name": "Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial", "disease": [ { "disease_id": "DOID:0050709", "name": "early infantile epileptic encephalopathy", "description": "A neonatal period electroclinical syndrome that is characterized by tonic spasms and partial seizures.", "url": "https://disease-ontology.org/term/DOID:0050709", "evidence": [ { "id": "0050709", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050709" } ], "weight": 0.0 }, { "disease_id": "DOID:0110409", "name": "retinitis pigmentosa 46", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the IDH3B gene on chromosome 20p13.", "url": "https://disease-ontology.org/term/DOID:0110409", "evidence": [ { "id": "0110409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110409" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" }, { "name": "isocitrate dehydrogenase (NAD+) activity", "id": "GO:0004449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004449", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" }, { "name": "isocitrate dehydrogenase complex (NAD+)", "id": "GO:0045242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045242", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" }, { "name": "isocitrate metabolic process", "id": "GO:0006102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006102", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" }, { "name": "glutamate biosynthetic process", "id": "GO:0006537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006537", "evidence": [ { "database": "UniProtKB", "id": "P28834", "url": "https://www.uniprot.org/uniprotkb/P28834" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P28834-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Ser343", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 343, "start_aa": "Ser", "end_pos": 343, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser343", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P28834", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P28834" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004982", "url": "https://www.yeastgenome.org/locus/S000004982" }, { "database": "iPTMnet", "id": "P28834", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28834" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28834-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 344, "start_aa": "Ser", "end_pos": 344, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser344", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P28834", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P28834" } ] } ] }, { "uniprot_canonical_ac": "P28834-1", "start_pos": "345", "end_pos": "345", "site_lbl": "Ser345", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 345, "start_aa": "Ser", "end_pos": 345, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser345", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P28834", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P28834" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004982", "url": "https://www.yeastgenome.org/locus/S000004982" }, { "database": "iPTMnet", "id": "P28834", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28834" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28834-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Thr346", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 346, "start_aa": "Thr", "end_pos": 346, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr346", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P28834", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P28834" } ] } ] }, { "uniprot_canonical_ac": "P28834-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Thr347", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 347, "start_aa": "Thr", "end_pos": 347, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr347", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P28834", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P28834" } ] } ] }, { "uniprot_canonical_ac": "P28834-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 350, "start_aa": "Thr", "end_pos": 350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr350", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P28834", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P28834" } ] } ] }, { "uniprot_canonical_ac": "P28834-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004982", "url": "https://www.yeastgenome.org/locus/S000004982" }, { "database": "iPTMnet", "id": "P28834", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28834" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28834-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004982", "url": "https://www.yeastgenome.org/locus/S000004982" }, { "database": "iPTMnet", "id": "P28834", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28834" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28834-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004982", "url": "https://www.yeastgenome.org/locus/S000004982" }, { "database": "iPTMnet", "id": "P28834", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28834" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28834-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Thr190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004982", "url": "https://www.yeastgenome.org/locus/S000004982" }, { "database": "iPTMnet", "id": "P28834", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28834" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P28834-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004982", "url": "https://www.yeastgenome.org/locus/S000004982" }, { "database": "iPTMnet", "id": "P28834", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P28834" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P28834-1" }, { "uniprot_canonical_ac": "P29029-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 562, "chemical_mass": 59015.0, "gene_names": "CTS1;CTS1;L8003.13;SCW2", "protein_name": "Endochitinase", "disease": [], "biological_process": [ { "name": "septum digestion after cytokinesis", "id": "GO:0000920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000920", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" }, { "name": "polysaccharide catabolic process", "id": "GO:0000272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000272", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" }, { "name": "chitin catabolic process", "id": "GO:0006032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006032", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitinase activity", "id": "GO:0004568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004568", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" }, { "name": "endochitinase activity", "id": "GO:0008843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008843", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "P29029", "url": "https://www.uniprot.org/uniprotkb/P29029" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29029-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Asn553", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 553, "start_aa": "Asn", "end_pos": 553, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn553", "evidence": [ { "id": "P29029", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29029#ptm_processing" } ] } ] } ], "record_id": "P29029-1" }, { "uniprot_canonical_ac": "P29340-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 183, "chemical_mass": 21118.0, "gene_names": "PEX4;PAS2;PEX4;UBC10", "protein_name": "Ubiquitin-conjugating enzyme E2 PEX4", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" } ], "biological_process": [ { "name": "peroxisome organization", "id": "GO:0007031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007031", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix, receptor recycling", "id": "GO:0016562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016562", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29340-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Cys105", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Decreases enzyme activity; when associated with S-146.", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" }, { "database": "PubMed", "id": "23896733", "url": "https://glygen.org/publication/PubMed/23896733" } ] } ] }, { "uniprot_canonical_ac": "P29340-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Cys115", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes monoubiquitination of PEX5.", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" }, { "database": "PubMed", "id": "17452527", "url": "https://glygen.org/publication/PubMed/17452527" } ] } ] }, { "uniprot_canonical_ac": "P29340-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Cys146", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Decreases enzyme activity; when associated with S-105.", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" }, { "database": "PubMed", "id": "23896733", "url": "https://glygen.org/publication/PubMed/23896733" } ] } ] }, { "uniprot_canonical_ac": "P29340-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Tyr172", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes binding to PEX22 and decreases PEX4 activity.", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" }, { "database": "PubMed", "id": "22085930", "url": "https://glygen.org/publication/PubMed/22085930" } ] }, { "sequence_org": "Y", "sequence_mut": "F", "comment": "Decreases binding to PEX22.", "evidence": [ { "database": "UniProtKB", "id": "P29340", "url": "https://www.uniprot.org/uniprotkb/P29340" }, { "database": "PubMed", "id": "22085930", "url": "https://glygen.org/publication/PubMed/22085930" } ] } ] } ], "record_id": "P29340-1" }, { "uniprot_canonical_ac": "P29453-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29453", "url": "https://www.uniprot.org/uniprotkb/P29453" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 256, "chemical_mass": 28112.0, "gene_names": "RPL8B;KRB1;RPL4B;RPL8B;SCL41", "protein_name": "Large ribosomal subunit protein eL8B", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P29453", "url": "https://www.uniprot.org/uniprotkb/P29453" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P29453", "url": "https://www.uniprot.org/uniprotkb/P29453" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P29453", "url": "https://www.uniprot.org/uniprotkb/P29453" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P29453", "url": "https://www.uniprot.org/uniprotkb/P29453" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P29453", "url": "https://www.uniprot.org/uniprotkb/P29453" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "P29453", "url": "https://www.uniprot.org/uniprotkb/P29453" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29453-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Thr188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Thr201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Ser255", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29453-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Thr30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003968", "url": "https://www.yeastgenome.org/locus/S000003968" }, { "database": "iPTMnet", "id": "P29453", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29453" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P29453-1" }, { "uniprot_canonical_ac": "P29461-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 750, "chemical_mass": 85868.0, "gene_names": "PTP2;PTP2", "protein_name": "Tyrosine-protein phosphatase 2", "disease": [ { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "pmid": "" }, { "name": "cellular hyperosmotic response", "id": "GO:0071474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071474", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "pmid": "" }, { "name": "maintenance of protein location in nucleus", "id": "GO:0051457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051457", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "pmid": "" }, { "name": "regulation of sporulation", "id": "GO:0043937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043937", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "pmid": "" }, { "name": "pheromone response MAPK cascade", "id": "GO:0071507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071507", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "pmid": "" }, { "name": "fungal-type cell wall organization or biogenesis", "id": "GO:0071852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071852", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "pmid": "" }, { "name": "negative regulation of cell integrity MAPK cascade", "id": "GO:1903138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903138", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29461-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Tyr257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005734", "url": "https://www.yeastgenome.org/locus/S000005734" }, { "database": "iPTMnet", "id": "P29461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29461" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P29461-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Ser258", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P29461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29461" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "25492886", "url": "https://glygen.org/publication/PubMed/25492886" }, { "database": "SGD", "id": "S000005734", "url": "https://www.yeastgenome.org/locus/S000005734" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29461-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Ser261", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005734", "url": "https://www.yeastgenome.org/locus/S000005734" }, { "database": "iPTMnet", "id": "P29461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29461" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P29461-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Ser395", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P29461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29461" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005734", "url": "https://www.yeastgenome.org/locus/S000005734" } ] } ] }, { "uniprot_canonical_ac": "P29461-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Ser430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P29461", "url": "https://www.uniprot.org/uniprotkb/P29461" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P29461", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29461" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005734", "url": "https://www.yeastgenome.org/locus/S000005734" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P29461-1" }, { "uniprot_canonical_ac": "P29465-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1165, "chemical_mass": 131601.0, "gene_names": "CHS3;CAL1;CHS3;CSD2;DIT101;KIT2;KTI2;YBR0305", "protein_name": "Chitin synthase 3", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "cell septum", "id": "GO:0030428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030428", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "chitosome", "id": "GO:0045009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045009", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" } ], "biological_process": [ { "name": "chitin biosynthetic process", "id": "GO:0006031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006031", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "ascospore wall assembly", "id": "GO:0030476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030476", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" }, { "name": "protein localization to bud neck", "id": "GO:0097271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097271", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin synthase activity", "id": "GO:0004100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004100", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29465-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Asn303", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 303, "start_aa": "Asn", "end_pos": 303, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn303", "evidence": [ { "id": "P29465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29465#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Asn332", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 332, "start_aa": "Asn", "end_pos": 332, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn332", "evidence": [ { "id": "P29465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29465#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Thr105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "1160", "end_pos": "1160", "site_lbl": "Ser1160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "1162", "end_pos": "1162", "site_lbl": "Ser1162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Thr148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "537", "end_pos": "537", "site_lbl": "Ser537", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Thr538", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Ser596", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "600", "end_pos": "600", "site_lbl": "Ser600", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Thr601", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000227", "url": "https://www.yeastgenome.org/locus/S000000227" }, { "database": "iPTMnet", "id": "P29465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "991", "end_pos": "991", "site_lbl": "Ser991", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces catalytic activity by 67%.", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" }, { "database": "PubMed", "id": "9760183", "url": "https://glygen.org/publication/PubMed/9760183" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "993", "end_pos": "993", "site_lbl": "Arg993", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces catalytic activity by 89%.", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" }, { "database": "PubMed", "id": "9760183", "url": "https://glygen.org/publication/PubMed/9760183" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "994", "end_pos": "994", "site_lbl": "Arg994", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Completely abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" }, { "database": "PubMed", "id": "9760183", "url": "https://glygen.org/publication/PubMed/9760183" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "995", "end_pos": "995", "site_lbl": "Arg995", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces catalytic activity by 87%.", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" }, { "database": "PubMed", "id": "9760183", "url": "https://glygen.org/publication/PubMed/9760183" } ] } ] }, { "uniprot_canonical_ac": "P29465-1", "start_pos": "999", "end_pos": "999", "site_lbl": "Ser999", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces catalytic activity by 59%.", "evidence": [ { "database": "UniProtKB", "id": "P29465", "url": "https://www.uniprot.org/uniprotkb/P29465" }, { "database": "PubMed", "id": "9760183", "url": "https://glygen.org/publication/PubMed/9760183" } ] } ] } ], "record_id": "P29465-1" }, { "uniprot_canonical_ac": "P29468-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 568, "chemical_mass": 64552.0, "gene_names": "PAP1;PAP1", "protein_name": "Poly(A) polymerase", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" } ], "pmid": "" }, { "name": "poly(A) RNA polymerase activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" } ], "pmid": "" }, { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" } ], "pmid": "" }, { "name": "sno(s)RNA 3'-end processing", "id": "GO:0031126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031126", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription, poly(A)-coupled", "id": "GO:0030846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030846", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29468-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001710", "url": "https://www.yeastgenome.org/locus/S000001710" }, { "database": "iPTMnet", "id": "P29468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29468" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001710", "url": "https://www.yeastgenome.org/locus/S000001710" }, { "database": "iPTMnet", "id": "P29468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29468" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P29468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29468" }, { "database": "SGD", "id": "S000001710", "url": "https://www.yeastgenome.org/locus/S000001710" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Ser494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001710", "url": "https://www.yeastgenome.org/locus/S000001710" }, { "database": "iPTMnet", "id": "P29468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29468" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "548", "end_pos": "548", "site_lbl": "Ser548", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P29468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29468" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001710", "url": "https://www.yeastgenome.org/locus/S000001710" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "550", "end_pos": "550", "site_lbl": "Ser550", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P29468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29468" }, { "database": "SGD", "id": "S000001710", "url": "https://www.yeastgenome.org/locus/S000001710" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "554", "end_pos": "554", "site_lbl": "Ser554", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001710", "url": "https://www.yeastgenome.org/locus/S000001710" }, { "database": "iPTMnet", "id": "P29468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29468" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Asp154", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" }, { "database": "PubMed", "id": "17850751", "url": "https://glygen.org/publication/PubMed/17850751" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Asn189", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Slightly reduced rate of adenylyltransfer.", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" }, { "database": "PubMed", "id": "17850751", "url": "https://glygen.org/publication/PubMed/17850751" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Lys215", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Reduces rate of adenylyltransfer about four-fold.", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" }, { "database": "PubMed", "id": "17850751", "url": "https://glygen.org/publication/PubMed/17850751" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Asn226", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Reduces rate of adenylyltransfer by half.", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" }, { "database": "PubMed", "id": "17850751", "url": "https://glygen.org/publication/PubMed/17850751" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "485", "end_pos": "485", "site_lbl": "Cys485", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "R", "comment": "Abolishes interaction with FIP1; when associated with Y-489.", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" }, { "database": "PubMed", "id": "18537269", "url": "https://glygen.org/publication/PubMed/18537269" } ] } ] }, { "uniprot_canonical_ac": "P29468-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Val489", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "Y", "comment": "Abolishes interaction with FIP1; when associated with R-485.", "evidence": [ { "database": "UniProtKB", "id": "P29468", "url": "https://www.uniprot.org/uniprotkb/P29468" }, { "database": "PubMed", "id": "18537269", "url": "https://glygen.org/publication/PubMed/18537269" } ] } ] } ], "record_id": "P29468-1" }, { "uniprot_canonical_ac": "P29478-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29478", "url": "https://www.uniprot.org/uniprotkb/P29478" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 273, "chemical_mass": 31170.0, "gene_names": "SEC65;SEC65;YM8339.14C", "protein_name": "Signal recognition particle subunit SEC65", "disease": [], "cellular_component": [ { "name": "signal recognition particle, endoplasmic reticulum targeting", "id": "GO:0005786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005786", "evidence": [ { "database": "UniProtKB", "id": "P29478", "url": "https://www.uniprot.org/uniprotkb/P29478" } ], "pmid": "" } ], "biological_process": [ { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "P29478", "url": "https://www.uniprot.org/uniprotkb/P29478" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition", "id": "GO:0006617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006617", "evidence": [ { "database": "UniProtKB", "id": "P29478", "url": "https://www.uniprot.org/uniprotkb/P29478" } ], "pmid": "" } ], "molecular_function": [ { "name": "7S RNA binding", "id": "GO:0008312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008312", "evidence": [ { "database": "UniProtKB", "id": "P29478", "url": "https://www.uniprot.org/uniprotkb/P29478" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29478-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004573", "url": "https://www.yeastgenome.org/locus/S000004573" }, { "database": "iPTMnet", "id": "P29478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29478" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29478-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Thr36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004573", "url": "https://www.yeastgenome.org/locus/S000004573" }, { "database": "iPTMnet", "id": "P29478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29478" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29478-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004573", "url": "https://www.yeastgenome.org/locus/S000004573" }, { "database": "iPTMnet", "id": "P29478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29478" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P29478-1" }, { "uniprot_canonical_ac": "P29509-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29509", "url": "https://www.uniprot.org/uniprotkb/P29509" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 319, "chemical_mass": 34238.0, "gene_names": "TRR1;D9476.5;TRR1", "protein_name": "Thioredoxin reductase 1", "disease": [], "molecular_function": [ { "name": "thioredoxin-disulfide reductase (NADPH) activity", "id": "GO:0004791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004791", "evidence": [ { "database": "UniProtKB", "id": "P29509", "url": "https://www.uniprot.org/uniprotkb/P29509" } ], "pmid": "" }, { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "P29509", "url": "https://www.uniprot.org/uniprotkb/P29509" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P29509", "url": "https://www.uniprot.org/uniprotkb/P29509" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P29509", "url": "https://www.uniprot.org/uniprotkb/P29509" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P29509", "url": "https://www.uniprot.org/uniprotkb/P29509" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P29509", "url": "https://www.uniprot.org/uniprotkb/P29509" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "P29509", "url": "https://www.uniprot.org/uniprotkb/P29509" } ], "pmid": "" }, { "name": "removal of superoxide radicals", "id": "GO:0019430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019430", "evidence": [ { "database": "UniProtKB", "id": "P29509", "url": "https://www.uniprot.org/uniprotkb/P29509" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29509-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Ser140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Ser165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Thr193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Thr251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Thr263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Thr271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Ser275", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Ser279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Ser300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Ser303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P29509", "url": "https://www.uniprot.org/uniprotkb/P29509" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Thr86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Ser88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Ser93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29509-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002761", "url": "https://www.yeastgenome.org/locus/S000002761" }, { "database": "iPTMnet", "id": "P29509", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29509" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P29509-1" }, { "uniprot_canonical_ac": "P29547-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 415, "chemical_mass": 47088.0, "gene_names": "CAM1;CAM1;TEF3", "protein_name": "Elongation factor 1-gamma 1", "disease": [], "biological_process": [ { "name": "regulation of translational termination", "id": "GO:0006449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006449", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" }, { "name": "translational elongation", "id": "GO:0006414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006414", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" }, { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29547-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005969", "url": "https://www.yeastgenome.org/locus/S000005969" }, { "database": "iPTMnet", "id": "P29547", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29547" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29547-1", "start_pos": "234", "end_pos": "234", "site_lbl": "Ser234", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005969", "url": "https://www.yeastgenome.org/locus/S000005969" }, { "database": "iPTMnet", "id": "P29547", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29547" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29547-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Ser276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005969", "url": "https://www.yeastgenome.org/locus/S000005969" }, { "database": "iPTMnet", "id": "P29547", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29547" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29547-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005969", "url": "https://www.yeastgenome.org/locus/S000005969" }, { "database": "iPTMnet", "id": "P29547", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29547" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29547-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Thr32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P29547", "url": "https://www.uniprot.org/uniprotkb/P29547" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P29547", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29547" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005969", "url": "https://www.yeastgenome.org/locus/S000005969" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29547-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Ser400", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005969", "url": "https://www.yeastgenome.org/locus/S000005969" }, { "database": "iPTMnet", "id": "P29547", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29547" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P29547-1" }, { "uniprot_canonical_ac": "P29704-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29704", "url": "https://www.uniprot.org/uniprotkb/P29704" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 444, "chemical_mass": 51720.0, "gene_names": "ERG9;ERG9", "protein_name": "Squalene synthase ERG9", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ergosterol biosynthetic process", "id": "GO:0006696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006696", "evidence": [ { "database": "UniProtKB", "id": "P29704", "url": "https://www.uniprot.org/uniprotkb/P29704" } ], "pmid": "" }, { "name": "isoprenoid biosynthetic process", "id": "GO:0008299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008299", "evidence": [ { "database": "UniProtKB", "id": "P29704", "url": "https://www.uniprot.org/uniprotkb/P29704" } ], "pmid": "" }, { "name": "farnesyl diphosphate metabolic process", "id": "GO:0045338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045338", "evidence": [ { "database": "UniProtKB", "id": "P29704", "url": "https://www.uniprot.org/uniprotkb/P29704" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P29704", "url": "https://www.uniprot.org/uniprotkb/P29704" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P29704", "url": "https://www.uniprot.org/uniprotkb/P29704" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P29704", "url": "https://www.uniprot.org/uniprotkb/P29704" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P29704", "url": "https://www.uniprot.org/uniprotkb/P29704" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P29704", "url": "https://www.uniprot.org/uniprotkb/P29704" } ], "pmid": "" } ], "molecular_function": [ { "name": "squalene synthase [NAD(P)H] activity", "id": "GO:0051996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051996", "evidence": [ { "database": "UniProtKB", "id": "P29704", "url": "https://www.uniprot.org/uniprotkb/P29704" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29704-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Ser244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001233", "url": "https://www.yeastgenome.org/locus/S000001233" }, { "database": "iPTMnet", "id": "P29704", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29704" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29704-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001233", "url": "https://www.yeastgenome.org/locus/S000001233" }, { "database": "iPTMnet", "id": "P29704", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29704" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P29704-1" }, { "uniprot_canonical_ac": "P29952-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 429, "chemical_mass": 48189.0, "gene_names": "PMI40;PMI40", "protein_name": "Mannose-6-phosphate isomerase", "disease": [ { "disease_id": "DOID:0050570", "name": "congenital disorder of glycosylation type I", "description": "A congenital disorder of glycosylation characterized by under-glycosylated serum glycoproteins.", "url": "https://disease-ontology.org/term/DOID:0050570", "evidence": [ { "id": "0050570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050570" } ], "weight": 0.0 }, { "disease_id": "DOID:0080554", "name": "congenital disorder of glycosylation Ib", "description": "A congenital disorder of glycosylation I that is characterized by protein-losing enteropathy, cyclic vomiting, profound hypoglycemia, failure to thrive, liver fibrosis, protein-losing enteropathy with hypoalbuminaemia, life-threatening intestinal bleeding of diffuse origin, protein C and S deficiency, low anti-thrombine III levels and has_material_basis_in compound heterozygous mutation in the gene encoding mannosephosphate isomerase on chromosome 15q24.", "url": "https://disease-ontology.org/term/DOID:0080554", "evidence": [ { "id": "0080554", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080554" } ], "weight": 0.0 }, { "disease_id": "DOID:2978", "name": "carbohydrate metabolic disorder", "description": "An inherited metabolic disorder that affect the catabolism and anabolism of carbohydrates.", "url": "https://disease-ontology.org/term/DOID:2978", "evidence": [ { "id": "2978", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2978" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell wall mannoprotein biosynthetic process", "id": "GO:0000032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000032", "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" } ], "pmid": "" }, { "name": "GDP-mannose biosynthetic process", "id": "GO:0009298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009298", "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" } ], "pmid": "" } ], "molecular_function": [ { "name": "mannose-6-phosphate isomerase activity", "id": "GO:0004476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004476", "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P29952-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P29952", "url": "https://www.uniprot.org/uniprotkb/P29952" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P29952", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29952" }, { "database": "SGD", "id": "S000000805", "url": "https://www.yeastgenome.org/locus/S000000805" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29952-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P29952", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29952" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000805", "url": "https://www.yeastgenome.org/locus/S000000805" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29952-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P29952", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29952" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000805", "url": "https://www.yeastgenome.org/locus/S000000805" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29952-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000805", "url": "https://www.yeastgenome.org/locus/S000000805" }, { "database": "iPTMnet", "id": "P29952", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29952" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P29952-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000805", "url": "https://www.yeastgenome.org/locus/S000000805" }, { "database": "iPTMnet", "id": "P29952", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29952" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29952-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000805", "url": "https://www.yeastgenome.org/locus/S000000805" }, { "database": "iPTMnet", "id": "P29952", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29952" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P29952-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000805", "url": "https://www.yeastgenome.org/locus/S000000805" }, { "database": "iPTMnet", "id": "P29952", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P29952" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P29952-1" }, { "uniprot_canonical_ac": "P30605-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 584, "chemical_mass": 63570.0, "gene_names": "ITR1;D9719.3;ITR1", "protein_name": "Myo-inositol transporter 1", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" }, { "name": "myo-inositol transport", "id": "GO:0015798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015798", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" }, { "name": "myo-inositol import across plasma membrane", "id": "GO:1904679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904679", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" }, { "name": "pseudohyphal growth", "id": "GO:0007124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007124", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" } ], "molecular_function": [ { "name": "myo-inositol:proton symporter activity", "id": "GO:0005366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005366", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" }, { "name": "myo-inositol transmembrane transporter activity", "id": "GO:0005365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005365", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P30605-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Asn371", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 371, "start_aa": "Asn", "end_pos": 371, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn371", "evidence": [ { "id": "P30605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30605#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Thr12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Thr291", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" }, { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Thr43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30605", "url": "https://www.uniprot.org/uniprotkb/P30605" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" }, { "database": "PubMed", "id": "22118465", "url": "https://glygen.org/publication/PubMed/22118465" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30605-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Thr577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002905", "url": "https://www.yeastgenome.org/locus/S000002905" }, { "database": "iPTMnet", "id": "P30605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30605" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P30605-1" }, { "uniprot_canonical_ac": "P30619-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 724, "chemical_mass": 83480.0, "gene_names": "SEC1;SEC1;YD8358.18C", "protein_name": "Protein transport protein SEC1", "disease": [ { "disease_id": "DOID:0050562", "name": "West syndrome", "description": "An infancy electroclinical syndrome that is characterized by infantile spasms, hypsarrhythmia on electroencephalogram and intellectual disability.", "url": "https://disease-ontology.org/term/DOID:0050562", "evidence": [ { "id": "0050562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050562" } ], "weight": 0.0 }, { "disease_id": "DOID:0050709", "name": "early infantile epileptic encephalopathy", "description": "A neonatal period electroclinical syndrome that is characterized by tonic spasms and partial seizures.", "url": "https://disease-ontology.org/term/DOID:0050709", "evidence": [ { "id": "0050709", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050709" } ], "weight": 0.0 }, { "disease_id": "DOID:0080436", "name": "developmental and epileptic encephalopathy 4", "description": "A developmental and epileptic encephalopathy characterized by onset of tonic seizures in early infancy and severely impaired psychomotor development that has_material_basis_in heterozygous mutation in the STXBP1 gene on chromosome 9q34.1.", "url": "https://disease-ontology.org/term/DOID:0080436", "evidence": [ { "id": "0080436", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080436" } ], "weight": 0.0 }, { "disease_id": "DOID:0110925", "name": "familial hemophagocytic lymphohistiocytosis 5", "description": "A hemophagocytic lymphohistiocytosis that has_material_basis_in a mutation of the STXBP2 gene on chromosome 19p13.2.", "url": "https://disease-ontology.org/term/DOID:0110925", "evidence": [ { "id": "0110925", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110925" } ], "weight": 0.0 }, { "disease_id": "DOID:0112202", "name": "developmental and epileptic encephalopathy", "description": "An electroclinical syndrome characterized by epileptiform activity and at least one other pathology that together contribute to cognitive and behavioral impairments including developmental delay or regression with onset anywhere from birth to adulthood.", "url": "https://disease-ontology.org/term/DOID:0112202", "evidence": [ { "id": "0112202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112202" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" }, { "name": "positive regulation of vesicle fusion", "id": "GO:0031340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031340", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" } ], "molecular_function": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "P30619", "url": "https://www.uniprot.org/uniprotkb/P30619" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P30619-1", "start_pos": "628", "end_pos": "628", "site_lbl": "Thr628", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002571", "url": "https://www.yeastgenome.org/locus/S000002571" }, { "database": "iPTMnet", "id": "P30619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30619" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30619-1", "start_pos": "630", "end_pos": "630", "site_lbl": "Thr630", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002571", "url": "https://www.yeastgenome.org/locus/S000002571" }, { "database": "iPTMnet", "id": "P30619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30619" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30619-1", "start_pos": "680", "end_pos": "680", "site_lbl": "Ser680", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002571", "url": "https://www.yeastgenome.org/locus/S000002571" }, { "database": "iPTMnet", "id": "P30619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30619" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30619-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Ser684", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002571", "url": "https://www.yeastgenome.org/locus/S000002571" }, { "database": "iPTMnet", "id": "P30619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30619" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30619-1", "start_pos": "687", "end_pos": "687", "site_lbl": "Ser687", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30619" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000002571", "url": "https://www.yeastgenome.org/locus/S000002571" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30619-1", "start_pos": "691", "end_pos": "691", "site_lbl": "Ser691", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30619" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000002571", "url": "https://www.yeastgenome.org/locus/S000002571" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30619-1", "start_pos": "697", "end_pos": "697", "site_lbl": "Ser697", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002571", "url": "https://www.yeastgenome.org/locus/S000002571" }, { "database": "iPTMnet", "id": "P30619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30619" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30619-1", "start_pos": "700", "end_pos": "700", "site_lbl": "Ser700", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002571", "url": "https://www.yeastgenome.org/locus/S000002571" }, { "database": "iPTMnet", "id": "P30619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30619" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P30619-1" }, { "uniprot_canonical_ac": "P30620-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 661, "chemical_mass": 76399.0, "gene_names": "PSO2;PSO2;SNM1;YM9375.06C", "protein_name": "DNA cross-link repair protein PSO2/SNM1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" } ], "pmid": "" }, { "name": "5'-3' DNA exonuclease activity", "id": "GO:0035312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035312", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" } ], "pmid": "" }, { "name": "5'-3' exonuclease activity", "id": "GO:0008409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008409", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P30620-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Thr104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "37649278", "url": "https://glygen.org/publication/PubMed/37649278" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Thr168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Thr179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "37649278", "url": "https://glygen.org/publication/PubMed/37649278" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "37649278", "url": "https://glygen.org/publication/PubMed/37649278" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "415", "end_pos": "415", "site_lbl": "Ser415", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "37649278", "url": "https://glygen.org/publication/PubMed/37649278" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "37649278", "url": "https://glygen.org/publication/PubMed/37649278" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Ser62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004745", "url": "https://www.yeastgenome.org/locus/S000004745" }, { "database": "iPTMnet", "id": "P30620", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30620" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Asp252", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abrogates exonuclease activity.", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" }, { "database": "PubMed", "id": "12509272", "url": "https://glygen.org/publication/PubMed/12509272" }, { "database": "PubMed", "id": "15590324", "url": "https://glygen.org/publication/PubMed/15590324" } ] } ] }, { "uniprot_canonical_ac": "P30620-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Gly256", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "In SNM1-2; increased sensitivity to DNA cross-linking agents at 36 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P30620", "url": "https://www.uniprot.org/uniprotkb/P30620" }, { "database": "PubMed", "id": "7526204", "url": "https://glygen.org/publication/PubMed/7526204" } ] } ] } ], "record_id": "P30620-1" }, { "uniprot_canonical_ac": "P30624-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 700, "chemical_mass": 77866.0, "gene_names": "FAA1;FAA1;O6136", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "disease": [ { "disease_id": "DOID:0050776", "name": "non-syndromic X-linked intellectual disability", "description": "A non-syndromic intellectual disability characterized by a X-linked inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0050776", "evidence": [ { "id": "0050776", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050776" } ], "weight": 0.0 }, { "disease_id": "DOID:0112050", "name": "non-syndromic X-linked intellectual disability 63", "description": "A non-syndromic X-linked intellectual disability characterized by moderate to severe nonprogressive intellectual disability in males and moderate intellectual disability to normal intelligence in females that has_material_basis_in heterozygous mutation in the ACSL4 gene on chromosome Xq23.", "url": "https://disease-ontology.org/term/DOID:0112050", "evidence": [ { "id": "0112050", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112050" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:14501", "name": "Sjogren-Larsson syndrome", "description": "A syndrome that is characterized by ichthyosis, mental retardation, spastic paraparesis, macular dystrophy, and leukoencephalopathy, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the aldehyde dehydrogenase 3 family member A2 (ALDH3A2) gene, which encodes fatty aldehyde dehydrogenase, on chromosome 17p11.", "url": "https://disease-ontology.org/term/DOID:14501", "evidence": [ { "id": "14501", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14501" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 } ], "biological_process": [ { "name": "long-chain fatty acid metabolic process", "id": "GO:0001676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001676", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" }, { "name": "long-chain fatty acid import into cell", "id": "GO:0044539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044539", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" }, { "name": "long-chain fatty-acyl-CoA metabolic process", "id": "GO:0035336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035336", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" }, { "name": "sphingoid long-chain base transport", "id": "GO:1905329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905329", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" }, { "name": "long-chain fatty acid-CoA ligase activity", "id": "GO:0004467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004467", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" }, { "name": "medium-chain fatty acid-CoA ligase activity", "id": "GO:0031956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031956", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P30624-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Tyr429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Ser435", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" }, { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Thr529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" }, { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "573", "end_pos": "573", "site_lbl": "Ser573", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" }, { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Ser621", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "622", "end_pos": "622", "site_lbl": "Ser622", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "698", "end_pos": "698", "site_lbl": "Ser698", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "699", "end_pos": "699", "site_lbl": "Ser699", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" }, { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "700", "end_pos": "700", "site_lbl": "Ser700", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" }, { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005844", "url": "https://www.yeastgenome.org/locus/S000005844" }, { "database": "iPTMnet", "id": "P30624", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30624" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Ser271", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Likely essential for ATP utilization. Reduces catalytic activity by 89%. Reduces the LCA palmitic acid transport activity by 71%. has no effect on the LCB dihydrosphingosine (DHS) transport activity.", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" }, { "database": "PubMed", "id": "27136724", "url": "https://glygen.org/publication/PubMed/27136724" } ] } ] }, { "uniprot_canonical_ac": "P30624-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Asp538", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes catalytic activity. Reduces the LCA palmitic acid transport activity by 96%. Abolishes the LCB dihydrosphingosine (DHS) transport activity.", "evidence": [ { "database": "UniProtKB", "id": "P30624", "url": "https://www.uniprot.org/uniprotkb/P30624" }, { "database": "PubMed", "id": "27136724", "url": "https://glygen.org/publication/PubMed/27136724" } ] } ] } ], "record_id": "P30624-1" }, { "uniprot_canonical_ac": "P30657-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P30657", "url": "https://www.uniprot.org/uniprotkb/P30657" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 266, "chemical_mass": 29443.0, "gene_names": "PRE4;PRE4", "protein_name": "Proteasome subunit beta type-7", "disease": [ { "disease_id": "DOID:0060916", "name": "proteasome-associated autoinflammatory syndrome 3", "description": "A proteasome-associated autoinflammatory syndrome that is characterized by nodular dermatitis, recurrent fever, myositis, panniculitis-induced lipodystrophy, lymphadenopathy and dysregulation of the immune response, particularly associated with abnormal type I interferon-induced gene expression pattern with onset in early infancy and that has_material_basis_in a homozygous mutation in the PSMB4 gene on chromosome 1q21 or a heterozygous mutation in the PSMB4 gene and a heterozygous mutation in the PSMB9 gene on chromosome 6p21.", "url": "https://disease-ontology.org/term/DOID:0060916", "evidence": [ { "id": "0060916", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060916" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "proteasome storage granule", "id": "GO:0034515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034515", "evidence": [ { "database": "UniProtKB", "id": "P30657", "url": "https://www.uniprot.org/uniprotkb/P30657" } ], "pmid": "" }, { "name": "proteasome core complex, beta-subunit complex", "id": "GO:0019774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019774", "evidence": [ { "database": "UniProtKB", "id": "P30657", "url": "https://www.uniprot.org/uniprotkb/P30657" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P30657", "url": "https://www.uniprot.org/uniprotkb/P30657" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P30657", "url": "https://www.uniprot.org/uniprotkb/P30657" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P30657", "url": "https://www.uniprot.org/uniprotkb/P30657" } ], "pmid": "" }, { "name": "proteasome assembly", "id": "GO:0043248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043248", "evidence": [ { "database": "UniProtKB", "id": "P30657", "url": "https://www.uniprot.org/uniprotkb/P30657" } ], "pmid": "" }, { "name": "proteasomal ubiquitin-independent protein catabolic process", "id": "GO:0010499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010499", "evidence": [ { "database": "UniProtKB", "id": "P30657", "url": "https://www.uniprot.org/uniprotkb/P30657" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P30657-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001946", "url": "https://www.yeastgenome.org/locus/S000001946" }, { "database": "iPTMnet", "id": "P30657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30657-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Thr263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001946", "url": "https://www.yeastgenome.org/locus/S000001946" }, { "database": "iPTMnet", "id": "P30657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30657-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Thr40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001946", "url": "https://www.yeastgenome.org/locus/S000001946" }, { "database": "iPTMnet", "id": "P30657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P30657-1" }, { "uniprot_canonical_ac": "P30665-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 933, "chemical_mass": 105003.0, "gene_names": "MCM4;CDC54;HCD21;MCM4;YP9531.13", "protein_name": "DNA replication licensing factor MCM4", "disease": [ { "disease_id": "DOID:0111967", "name": "immunodeficiency 54", "description": "A NK cell deficiency characterized by severe intra- and extrauterine growth retardation, microcephaly, decreased numbers of CD56(dim) natural killer cells, adrenal insufficiency, and recurrent viral infections that has_material_basis_in homozygous or compound heterozygous mutation in the MCM4 gene on chromosome 8q11.21.", "url": "https://disease-ontology.org/term/DOID:0111967", "evidence": [ { "id": "0111967", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111967" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pre-replicative complex", "id": "GO:0005656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005656", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "DNA replication preinitiation complex", "id": "GO:0031261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031261", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "MCM complex", "id": "GO:0042555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042555", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "CMG complex", "id": "GO:0071162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071162", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "MCM core complex", "id": "GO:0097373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097373", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" } ], "biological_process": [ { "name": "pre-replicative complex assembly involved in nuclear cell cycle DNA replication", "id": "GO:0006267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006267", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "DNA strand elongation involved in DNA replication", "id": "GO:0006271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006271", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "mitotic DNA replication initiation", "id": "GO:1902975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902975", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "nuclear DNA replication", "id": "GO:0033260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033260", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" }, { "name": "premeiotic DNA replication", "id": "GO:0006279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006279", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P30665-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 119, "start_aa": "Ser", "end_pos": 119, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser119", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 120, "start_aa": "Ser", "end_pos": 120, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser120", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 121, "start_aa": "Ser", "end_pos": 121, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser121", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 122, "start_aa": "Ser", "end_pos": 122, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser122", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ser164", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 164, "start_aa": "Ser", "end_pos": 164, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser164", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Ser165", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 165, "start_aa": "Ser", "end_pos": 165, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser165", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 166, "start_aa": "Ser", "end_pos": 166, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser166", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 167, "start_aa": "Ser", "end_pos": 167, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser167", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 171, "start_aa": "Ser", "end_pos": 171, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser171", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 174, "start_aa": "Ser", "end_pos": 174, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser174", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 52, "start_aa": "Ser", "end_pos": 52, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser52", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 56, "start_aa": "Ser", "end_pos": 56, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser56", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 75, "start_aa": "Ser", "end_pos": 75, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser75", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 76, "start_aa": "Ser", "end_pos": 76, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser76", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 77, "start_aa": "Ser", "end_pos": 77, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser77", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P30665", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P30665" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Thr118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Thr140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "18321994", "url": "https://glygen.org/publication/PubMed/18321994" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Thr160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "18321994", "url": "https://glygen.org/publication/PubMed/18321994" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "18321994", "url": "https://glygen.org/publication/PubMed/18321994" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Ser42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "638", "end_pos": "638", "site_lbl": "Ser638", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "18321994", "url": "https://glygen.org/publication/PubMed/18321994" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "737", "end_pos": "737", "site_lbl": "Ser737", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "18321994", "url": "https://glygen.org/publication/PubMed/18321994" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30665", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30665" }, { "database": "PubMed", "id": "21070963", "url": "https://glygen.org/publication/PubMed/21070963" }, { "database": "SGD", "id": "S000006223", "url": "https://www.yeastgenome.org/locus/S000006223" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "34963704", "url": "https://glygen.org/publication/PubMed/34963704" } ] } ] }, { "uniprot_canonical_ac": "P30665-1", "start_pos": "574", "end_pos": "574", "site_lbl": "Lys574", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of MCM2-7 complex helicase activity.", "evidence": [ { "database": "UniProtKB", "id": "P30665", "url": "https://www.uniprot.org/uniprotkb/P30665" }, { "database": "PubMed", "id": "18657510", "url": "https://glygen.org/publication/PubMed/18657510" } ] } ] } ], "record_id": "P30665-1" }, { "uniprot_canonical_ac": "P30771-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 971, "chemical_mass": 109430.0, "gene_names": "NAM7;IFS2;MOF4;NAM7;SUP113;SUT2;UPF1;YM9582.05C", "protein_name": "ATP-dependent helicase NAM7", "disease": [ { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of translational termination", "id": "GO:0006449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006449", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay", "id": "GO:0070478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070478", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "cytoplasmic RNA surveillance", "id": "GO:0071026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071026", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "ribosomal small subunit binding", "id": "GO:0043024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043024", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" }, { "name": "double-stranded DNA helicase activity", "id": "GO:0036121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036121", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P30771-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Ser199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Ser495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Thr50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "527", "end_pos": "527", "site_lbl": "Ser527", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Ser54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "738", "end_pos": "738", "site_lbl": "Tyr738", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "24198248", "url": "https://glygen.org/publication/PubMed/24198248" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "742", "end_pos": "742", "site_lbl": "Tyr742", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "24198248", "url": "https://glygen.org/publication/PubMed/24198248" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "748", "end_pos": "748", "site_lbl": "Ser748", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "24198248", "url": "https://glygen.org/publication/PubMed/24198248" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "754", "end_pos": "754", "site_lbl": "Tyr754", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "24198248", "url": "https://glygen.org/publication/PubMed/24198248" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "869", "end_pos": "869", "site_lbl": "Ser869", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "884", "end_pos": "884", "site_lbl": "Ser884", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "887", "end_pos": "887", "site_lbl": "Ser887", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "924", "end_pos": "924", "site_lbl": "Ser924", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "943", "end_pos": "943", "site_lbl": "Ser943", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "963", "end_pos": "963", "site_lbl": "Ser963", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "967", "end_pos": "967", "site_lbl": "Ser967", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004685", "url": "https://www.yeastgenome.org/locus/S000004685" }, { "database": "iPTMnet", "id": "P30771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Lys436", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "Q", "comment": "Loss of ATPase, DNA and RNA helicase activity, still binds RNA.", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" }, { "database": "PubMed", "id": "7489520", "url": "https://glygen.org/publication/PubMed/7489520" }, { "database": "PubMed", "id": "8816461", "url": "https://glygen.org/publication/PubMed/8816461" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ala484", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "H", "comment": "Decreased DNA binding, decreased helicase processivity.", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" }, { "database": "PubMed", "id": "30218034", "url": "https://glygen.org/publication/PubMed/30218034" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "485", "end_pos": "485", "site_lbl": "Lys485", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "P", "comment": "Decreased DNA binding, decreased helicase processivity.", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" }, { "database": "PubMed", "id": "30218034", "url": "https://glygen.org/publication/PubMed/30218034" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "486", "end_pos": "486", "site_lbl": "Ser486", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No change in DNA binding or helicase processivity.", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" }, { "database": "PubMed", "id": "30218034", "url": "https://glygen.org/publication/PubMed/30218034" } ] } ] }, { "uniprot_canonical_ac": "P30771-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Arg487", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "S", "comment": "Decreased DNA binding, decreased helicase processivity.", "evidence": [ { "database": "UniProtKB", "id": "P30771", "url": "https://www.uniprot.org/uniprotkb/P30771" }, { "database": "PubMed", "id": "30218034", "url": "https://glygen.org/publication/PubMed/30218034" } ] } ] } ], "record_id": "P30771-1" }, { "uniprot_canonical_ac": "P30775-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P30775", "url": "https://www.uniprot.org/uniprotkb/P30775" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 413, "chemical_mass": 46770.0, "gene_names": "MRF1;MRF1", "protein_name": "Peptide chain release factor 1, mitochondrial", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P30775", "url": "https://www.uniprot.org/uniprotkb/P30775" } ], "pmid": "" } ], "biological_process": [ { "name": "translational termination", "id": "GO:0006415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006415", "evidence": [ { "database": "UniProtKB", "id": "P30775", "url": "https://www.uniprot.org/uniprotkb/P30775" } ], "pmid": "" }, { "name": "mitochondrial translational termination", "id": "GO:0070126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070126", "evidence": [ { "database": "UniProtKB", "id": "P30775", "url": "https://www.uniprot.org/uniprotkb/P30775" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "P30775", "url": "https://www.uniprot.org/uniprotkb/P30775" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation release factor activity", "id": "GO:0003747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003747", "evidence": [ { "database": "UniProtKB", "id": "P30775", "url": "https://www.uniprot.org/uniprotkb/P30775" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P30775-1" }, { "uniprot_canonical_ac": "P30902-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P30902", "url": "https://www.uniprot.org/uniprotkb/P30902" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 174, "chemical_mass": 19810.0, "gene_names": "ATP7;ATP7", "protein_name": "ATP synthase subunit d, mitochondrial", "disease": [ { "disease_id": "DOID:0050328", "name": "congenital hypothyroidism", "description": "A hypothyroidism that is present at birth.", "url": "https://disease-ontology.org/term/DOID:0050328", "evidence": [ { "id": "0050328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050328" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P30902", "url": "https://www.uniprot.org/uniprotkb/P30902" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P30902", "url": "https://www.uniprot.org/uniprotkb/P30902" } ], "pmid": "" }, { "name": "proton-transporting ATP synthase complex", "id": "GO:0045259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045259", "evidence": [ { "database": "UniProtKB", "id": "P30902", "url": "https://www.uniprot.org/uniprotkb/P30902" } ], "pmid": "" } ], "molecular_function": [ { "name": "proton transmembrane transporter activity", "id": "GO:0015078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015078", "evidence": [ { "database": "UniProtKB", "id": "P30902", "url": "https://www.uniprot.org/uniprotkb/P30902" } ], "pmid": "" } ], "biological_process": [ { "name": "proton motive force-driven ATP synthesis", "id": "GO:0015986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015986", "evidence": [ { "database": "UniProtKB", "id": "P30902", "url": "https://www.uniprot.org/uniprotkb/P30902" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P30902-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001499", "url": "https://www.yeastgenome.org/locus/S000001499" }, { "database": "iPTMnet", "id": "P30902", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30902" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30902-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001499", "url": "https://www.yeastgenome.org/locus/S000001499" }, { "database": "iPTMnet", "id": "P30902", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30902" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P30902-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Thr121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001499", "url": "https://www.yeastgenome.org/locus/S000001499" }, { "database": "iPTMnet", "id": "P30902", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30902" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30902-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001499", "url": "https://www.yeastgenome.org/locus/S000001499" }, { "database": "iPTMnet", "id": "P30902", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30902" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30902-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001499", "url": "https://www.yeastgenome.org/locus/S000001499" }, { "database": "iPTMnet", "id": "P30902", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30902" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P30902-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001499", "url": "https://www.yeastgenome.org/locus/S000001499" }, { "database": "iPTMnet", "id": "P30902", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30902" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P30902-1" }, { "uniprot_canonical_ac": "P30952-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P30952", "url": "https://www.uniprot.org/uniprotkb/P30952" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 554, "chemical_mass": 62791.0, "gene_names": "MLS1;MLS1;N1921", "protein_name": "Malate synthase 1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P30952", "url": "https://www.uniprot.org/uniprotkb/P30952" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P30952", "url": "https://www.uniprot.org/uniprotkb/P30952" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "P30952", "url": "https://www.uniprot.org/uniprotkb/P30952" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P30952", "url": "https://www.uniprot.org/uniprotkb/P30952" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "P30952", "url": "https://www.uniprot.org/uniprotkb/P30952" } ], "pmid": "" }, { "name": "glyoxylate cycle", "id": "GO:0006097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006097", "evidence": [ { "database": "UniProtKB", "id": "P30952", "url": "https://www.uniprot.org/uniprotkb/P30952" } ], "pmid": "" } ], "molecular_function": [ { "name": "malate synthase activity", "id": "GO:0004474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004474", "evidence": [ { "database": "UniProtKB", "id": "P30952", "url": "https://www.uniprot.org/uniprotkb/P30952" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P30952-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Thr157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005061", "url": "https://www.yeastgenome.org/locus/S000005061" }, { "database": "iPTMnet", "id": "P30952", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P30952" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P30952-1" }, { "uniprot_canonical_ac": "P31109-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 117, "chemical_mass": 13201.0, "gene_names": "SNC1;SNC1", "protein_name": "Synaptobrevin homolog 1", "disease": [ { "disease_id": "DOID:0050772", "name": "spastic ataxia 1", "description": "A spastic ataxia characterized by early-onset cerebellar ataxia, spasticity, pyramidal syndrome and peripheral neuropathy, has_material_basis_in autosomal dominant inheritance of heterozygous mutation in the VAMP1 gene on chromosome 12p13.", "url": "https://disease-ontology.org/term/DOID:0050772", "evidence": [ { "id": "0050772", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050772" } ], "weight": 0.0 }, { "disease_id": "DOID:3635", "name": "congenital myasthenic syndrome", "description": "A neuromuscular junction disease that is characterized by weakness and easy fatiguability resulting from a genetic defect at the junction where the nerve stimulates muscle activity that result in muscle weakness and may affect nerve cells (presynaptic), muscle cells (postsynaptic) or the space between nerve and muscle cells (synaptic).", "url": "https://disease-ontology.org/term/DOID:3635", "evidence": [ { "id": "3635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3635" } ], "weight": 0.0 } ], "biological_process": [ { "name": "Golgi vesicle fusion to target membrane", "id": "GO:0048210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048210", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "SNARE complex assembly", "id": "GO:0035493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035493", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "vesicle fusion with Golgi apparatus", "id": "GO:0048280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048280", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "vesicle fusion to plasma membrane", "id": "GO:0099500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099500", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "ascospore-type prospore assembly", "id": "GO:0031321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031321", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P31109", "url": "https://www.uniprot.org/uniprotkb/P31109" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31109-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Tyr10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000028", "url": "https://www.yeastgenome.org/locus/S000000028" }, { "database": "iPTMnet", "id": "P31109", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31109" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] } ] }, { "uniprot_canonical_ac": "P31109-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31109", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31109" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000000028", "url": "https://www.yeastgenome.org/locus/S000000028" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31109-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000028", "url": "https://www.yeastgenome.org/locus/S000000028" }, { "database": "iPTMnet", "id": "P31109", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31109" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31109-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000028", "url": "https://www.yeastgenome.org/locus/S000000028" }, { "database": "iPTMnet", "id": "P31109", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31109" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31109-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000028", "url": "https://www.yeastgenome.org/locus/S000000028" }, { "database": "iPTMnet", "id": "P31109", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31109" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31109-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31109", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31109" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000028", "url": "https://www.yeastgenome.org/locus/S000000028" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P31109-1" }, { "uniprot_canonical_ac": "P31111-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 875, "chemical_mass": 100035.0, "gene_names": "ZIP1;D9819.9;ZIP1", "protein_name": "Synaptonemal complex protein ZIP1", "disease": [], "biological_process": [ { "name": "protein localization to site of double-strand break", "id": "GO:1990166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990166", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "positive regulation of protein sumoylation", "id": "GO:0033235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033235", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "negative regulation of reciprocal meiotic recombination", "id": "GO:0045128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045128", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "positive regulation of strand invasion", "id": "GO:0098530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098530", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "homologous recombination", "id": "GO:0035825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035825", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "mitotic actomyosin contractile ring contraction", "id": "GO:1902404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902404", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" } ], "cellular_component": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "synaptonemal complex", "id": "GO:0000795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000795", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "transverse filament", "id": "GO:0000802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000802", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "mitotic actomyosin contractile ring", "id": "GO:0110085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110085", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "SUMO polymer binding", "id": "GO:0032184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032184", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31111-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Ser473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Thr475", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Ser481", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31111", "url": "https://www.uniprot.org/uniprotkb/P31111" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20951350", "url": "https://glygen.org/publication/PubMed/20951350" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20951350", "url": "https://glygen.org/publication/PubMed/20951350" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20951350", "url": "https://glygen.org/publication/PubMed/20951350" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "761", "end_pos": "761", "site_lbl": "Ser761", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "763", "end_pos": "763", "site_lbl": "Ser763", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "783", "end_pos": "783", "site_lbl": "Ser783", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "815", "end_pos": "815", "site_lbl": "Ser815", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "26682552", "url": "https://glygen.org/publication/PubMed/26682552" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "816", "end_pos": "816", "site_lbl": "Ser816", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "26682552", "url": "https://glygen.org/publication/PubMed/26682552" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "818", "end_pos": "818", "site_lbl": "Ser818", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "26682552", "url": "https://glygen.org/publication/PubMed/26682552" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "828", "end_pos": "828", "site_lbl": "Ser828", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31111-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Ser89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002693", "url": "https://www.yeastgenome.org/locus/S000002693" }, { "database": "iPTMnet", "id": "P31111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31111" }, { "database": "PubMed", "id": "20825495", "url": "https://glygen.org/publication/PubMed/20825495" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P31111-1" }, { "uniprot_canonical_ac": "P31115-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31115", "url": "https://www.uniprot.org/uniprotkb/P31115" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 442, "chemical_mass": 50889.0, "gene_names": "DEG1;DEG1;HRM3;PUS3", "protein_name": "tRNA pseudouridine(38/39) synthase", "disease": [], "biological_process": [ { "name": "tRNA pseudouridine synthesis", "id": "GO:0031119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031119", "evidence": [ { "database": "UniProtKB", "id": "P31115", "url": "https://www.uniprot.org/uniprotkb/P31115" } ], "pmid": "" }, { "name": "mRNA pseudouridine synthesis", "id": "GO:1990481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990481", "evidence": [ { "database": "UniProtKB", "id": "P31115", "url": "https://www.uniprot.org/uniprotkb/P31115" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P31115", "url": "https://www.uniprot.org/uniprotkb/P31115" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "P31115", "url": "https://www.uniprot.org/uniprotkb/P31115" } ], "pmid": "" }, { "name": "tRNA pseudouridine(38/39) synthase activity", "id": "GO:0160154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160154", "evidence": [ { "database": "UniProtKB", "id": "P31115", "url": "https://www.uniprot.org/uniprotkb/P31115" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31115", "url": "https://www.uniprot.org/uniprotkb/P31115" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P31115", "url": "https://www.uniprot.org/uniprotkb/P31115" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P31115", "url": "https://www.uniprot.org/uniprotkb/P31115" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31115-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Ser258", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 258, "start_aa": "Ser", "end_pos": 258, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser258", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P31115", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P31115" } ] } ] }, { "uniprot_canonical_ac": "P31115-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Thr262", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 262, "start_aa": "Thr", "end_pos": 262, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr262", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P31115", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P31115" } ] } ] }, { "uniprot_canonical_ac": "P31115-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31115" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001895", "url": "https://www.yeastgenome.org/locus/S000001895" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P31115-1" }, { "uniprot_canonical_ac": "P31116-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 359, "chemical_mass": 38502.0, "gene_names": "HOM6;HOM6;J2132;THR6", "protein_name": "Homoserine dehydrogenase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" } ], "pmid": "" } ], "molecular_function": [ { "name": "NAD+ binding", "id": "GO:0070403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070403", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" } ], "pmid": "" }, { "name": "homoserine dehydrogenase activity", "id": "GO:0004412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004412", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" } ], "pmid": "" } ], "biological_process": [ { "name": "methionine biosynthetic process", "id": "GO:0009086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009086", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" } ], "pmid": "" }, { "name": "threonine biosynthetic process", "id": "GO:0009088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009088", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" } ], "pmid": "" }, { "name": "aspartate family amino acid biosynthetic process", "id": "GO:0009067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009067", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" } ], "pmid": "" }, { "name": "homoserine biosynthetic process", "id": "GO:0009090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009090", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31116-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "automatic_literature_mining", "site_category_dict": { "automatic_literature_mining": true }, "site_seq": "S", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 29, "start_aa": "Ser", "end_pos": 29, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser29", "evidence": [ { "id": "1633844", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/1633844" }, { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "mining_tool": "GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "GlycoSiteMiner_1.0" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Thr344", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 344, "start_aa": "Thr", "end_pos": 344, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr344", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Thr207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Ser237", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Ser297", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Ser299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Ser308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Ser317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Ser322", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Thr329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003900", "url": "https://www.yeastgenome.org/locus/S000003900" }, { "database": "iPTMnet", "id": "P31116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31116" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Lys117", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" }, { "database": "PubMed", "id": "10700284", "url": "https://glygen.org/publication/PubMed/10700284" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Glu208", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "D", "comment": "Increases KM for aspartate-semialdehyde 48-fold and reduces kcat by 50%.", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" }, { "database": "PubMed", "id": "10700284", "url": "https://glygen.org/publication/PubMed/10700284" } ] }, { "sequence_org": "E", "sequence_mut": "L", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" }, { "database": "PubMed", "id": "10700284", "url": "https://glygen.org/publication/PubMed/10700284" } ] }, { "sequence_org": "E", "sequence_mut": "Q", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" }, { "database": "PubMed", "id": "10700284", "url": "https://glygen.org/publication/PubMed/10700284" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Asp219", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "L", "comment": "Reduces kcat 150-fold.", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" }, { "database": "PubMed", "id": "10700284", "url": "https://glygen.org/publication/PubMed/10700284" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Lys223", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "V", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" }, { "database": "PubMed", "id": "10700284", "url": "https://glygen.org/publication/PubMed/10700284" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "309", "end_pos": "309", "site_lbl": "His309", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Reduces kcat 40-fold. Affects dimer formation.", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" }, { "database": "PubMed", "id": "11341914", "url": "https://glygen.org/publication/PubMed/11341914" } ] } ] }, { "uniprot_canonical_ac": "P31116-1", "start_pos": "79", "end_pos": "79", "site_lbl": "His79", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Reduces kcat 2-fold.", "evidence": [ { "database": "UniProtKB", "id": "P31116", "url": "https://www.uniprot.org/uniprotkb/P31116" }, { "database": "PubMed", "id": "11341914", "url": "https://glygen.org/publication/PubMed/11341914" } ] } ] } ], "record_id": "P31116-1" }, { "uniprot_canonical_ac": "P31373-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 394, "chemical_mass": 42542.0, "gene_names": "CYS3;CYI1;CYS3;FUN35;STR1", "protein_name": "Cystathionine gamma-lyase", "disease": [ { "disease_id": "DOID:0090142", "name": "cystathioninuria", "description": "An amino acid metabolic disorder that is characterized by elevated plasma and urinary cystathionine levels that has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the gene encoding cystathionine gamma-lyase (CTH) on chromosome 1p31.", "url": "https://disease-ontology.org/term/DOID:0090142", "evidence": [ { "id": "0090142", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090142" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 }, { "disease_id": "DOID:9263", "name": "homocystinuria", "description": "An amino acid metabolic disorder that involves an accumulation of homocysteine in the serum and an increased excretion of homocysteine in the urine.", "url": "https://disease-ontology.org/term/DOID:9263", "evidence": [ { "id": "9263", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9263" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" } ], "pmid": "" }, { "name": "cystathionine gamma-lyase activity", "id": "GO:0004123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004123", "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" } ], "pmid": "" }, { "name": "cysteine-S-conjugate beta-lyase activity", "id": "GO:0047804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047804", "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of hydrogen sulfide biosynthetic process", "id": "GO:1904828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904828", "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" } ], "pmid": "" }, { "name": "transsulfuration", "id": "GO:0019346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019346", "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" } ], "pmid": "" }, { "name": "cysteine biosynthetic process via cystathionine", "id": "GO:0019343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019343", "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" } ], "pmid": "" }, { "name": "cysteine biosynthetic process", "id": "GO:0019344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019344", "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31373-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Thr147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31373-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31373-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Ser310", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31373-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Ser325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P31373-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31373", "url": "https://www.uniprot.org/uniprotkb/P31373" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31373-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31373-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31373-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Thr47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31373-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31373-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31373-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000010", "url": "https://www.yeastgenome.org/locus/S000000010" }, { "database": "iPTMnet", "id": "P31373", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31373" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P31373-1" }, { "uniprot_canonical_ac": "P31374-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1356, "chemical_mass": 152332.0, "gene_names": "PSK1;FUN31;PSK1;YAL002", "protein_name": "Serine/threonine-protein kinase PSK1", "disease": [], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" }, { "name": "negative regulation of glycogen biosynthetic process", "id": "GO:0045719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045719", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" }, { "name": "regulation of (1->6)-beta-D-glucan biosynthetic process", "id": "GO:0060917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060917", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31374-1", "start_pos": "451", "end_pos": "451", "site_lbl": "Thr451", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 451, "start_aa": "Thr", "end_pos": 451, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr451", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P31374", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P31374" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "453", "end_pos": "453", "site_lbl": "Thr453", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 453, "start_aa": "Thr", "end_pos": 453, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr453", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P31374", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P31374" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "454", "end_pos": "454", "site_lbl": "Ser454", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 454, "start_aa": "Ser", "end_pos": 454, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser454", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P31374", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P31374" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Thr455", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 455, "start_aa": "Thr", "end_pos": 455, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr455", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P31374", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P31374" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1013", "end_pos": "1013", "site_lbl": "Ser1013", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1016", "end_pos": "1016", "site_lbl": "Ser1016", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1018", "end_pos": "1018", "site_lbl": "Ser1018", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1020", "end_pos": "1020", "site_lbl": "Ser1020", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1021", "end_pos": "1021", "site_lbl": "Thr1021", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1023", "end_pos": "1023", "site_lbl": "Ser1023", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1027", "end_pos": "1027", "site_lbl": "Ser1027", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1030", "end_pos": "1030", "site_lbl": "Ser1030", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1035", "end_pos": "1035", "site_lbl": "Ser1035", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1048", "end_pos": "1048", "site_lbl": "Thr1048", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1055", "end_pos": "1055", "site_lbl": "Ser1055", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1074", "end_pos": "1074", "site_lbl": "Ser1074", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1079", "end_pos": "1079", "site_lbl": "Thr1079", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "1094", "end_pos": "1094", "site_lbl": "Ser1094", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Thr236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Ser247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Ser255", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Ser275", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Ser286", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Ser291", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Thr300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Ser301", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Ser327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Ser364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Thr37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Tyr54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Thr599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Ser601", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "607", "end_pos": "607", "site_lbl": "Ser607", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "608", "end_pos": "608", "site_lbl": "Ser608", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Thr610", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "612", "end_pos": "612", "site_lbl": "Ser612", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Ser626", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Ser632", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Thr63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "649", "end_pos": "649", "site_lbl": "Ser649", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Ser652", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "654", "end_pos": "654", "site_lbl": "Ser654", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "655", "end_pos": "655", "site_lbl": "Ser655", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "656", "end_pos": "656", "site_lbl": "Ser656", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "784", "end_pos": "784", "site_lbl": "Ser784", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "786", "end_pos": "786", "site_lbl": "Thr786", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "905", "end_pos": "905", "site_lbl": "Ser905", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "906", "end_pos": "906", "site_lbl": "Ser906", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "914", "end_pos": "914", "site_lbl": "Ser914", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "915", "end_pos": "915", "site_lbl": "Ser915", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "918", "end_pos": "918", "site_lbl": "Ser918", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "919", "end_pos": "919", "site_lbl": "Thr919", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "921", "end_pos": "921", "site_lbl": "Thr921", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "926", "end_pos": "926", "site_lbl": "Ser926", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31374", "url": "https://www.uniprot.org/uniprotkb/P31374" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "929", "end_pos": "929", "site_lbl": "Ser929", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "930", "end_pos": "930", "site_lbl": "Thr930", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "953", "end_pos": "953", "site_lbl": "Ser953", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "955", "end_pos": "955", "site_lbl": "Ser955", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "956", "end_pos": "956", "site_lbl": "Thr956", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31374-1", "start_pos": "992", "end_pos": "992", "site_lbl": "Ser992", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000015", "url": "https://www.yeastgenome.org/locus/S000000015" }, { "database": "iPTMnet", "id": "P31374", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P31374-1" }, { "uniprot_canonical_ac": "P31376-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 625, "chemical_mass": 72514.0, "gene_names": "SWC3;FUN36;SWC1;SWC3", "protein_name": "SWR1-complex protein 3", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "pmid": "" }, { "name": "endoplasmic reticulum organization", "id": "GO:0007029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007029", "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleosomal DNA binding", "id": "GO:0031492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031492", "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "pmid": "" }, { "name": "ATP-dependent H2AZ histone chaperone activity", "id": "GO:0140849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140849", "evidence": [ { "database": "UniProtKB", "id": "P31376", "url": "https://www.uniprot.org/uniprotkb/P31376" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31376-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Thr133", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 133, "start_aa": "Thr", "end_pos": 133, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr133", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Thr137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Ser268", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "331", "end_pos": "331", "site_lbl": "Ser331", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Thr356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Thr389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Ser523", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31376-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000009", "url": "https://www.yeastgenome.org/locus/S000000009" }, { "database": "iPTMnet", "id": "P31376", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31376" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P31376-1" }, { "uniprot_canonical_ac": "P31377-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 255, "chemical_mass": 29049.0, "gene_names": "SYN8;FUN34;SLT2;SYN8;UIP2", "protein_name": "Syntaxin-8", "disease": [], "biological_process": [ { "name": "Golgi vesicle fusion to target membrane", "id": "GO:0048210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048210", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "vesicle docking", "id": "GO:0048278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048278", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" }, { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "P31377", "url": "https://www.uniprot.org/uniprotkb/P31377" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31377-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Thr73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000012", "url": "https://www.yeastgenome.org/locus/S000000012" }, { "database": "iPTMnet", "id": "P31377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31377-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Tyr80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000012", "url": "https://www.yeastgenome.org/locus/S000000012" }, { "database": "iPTMnet", "id": "P31377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31377-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000012", "url": "https://www.yeastgenome.org/locus/S000000012" }, { "database": "iPTMnet", "id": "P31377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31377-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Ser97", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000012", "url": "https://www.yeastgenome.org/locus/S000000012" }, { "database": "iPTMnet", "id": "P31377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P31377-1" }, { "uniprot_canonical_ac": "P31378-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 399, "chemical_mass": 45577.0, "gene_names": "NTG1;FUN33;NTG1;OGG2;SCR1;ogg2", "protein_name": "Endonuclease III homolog 1", "disease": [ { "disease_id": "DOID:0080411", "name": "familial adenomatous polyposis 3", "description": "A familial adenomatous polyposis that has_material_basis_in homozygous or compound heterozygous mutation in the NTHL1 gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0080411", "evidence": [ { "id": "0080411", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080411" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of mitochondrial DNA replication", "id": "GO:0090297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090297", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" }, { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" }, { "name": "base-excision repair, AP site formation", "id": "GO:0006285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006285", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" }, { "name": "class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0140078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140078", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" }, { "name": "oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity", "id": "GO:0000703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000703", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" }, { "name": "oxidized purine nucleobase lesion DNA N-glycosylase activity", "id": "GO:0008534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008534", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31378-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Ser341", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000013", "url": "https://www.yeastgenome.org/locus/S000000013" }, { "database": "iPTMnet", "id": "P31378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31378" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31378-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000013", "url": "https://www.yeastgenome.org/locus/S000000013" }, { "database": "iPTMnet", "id": "P31378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31378" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31378-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Lys243", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "Q", "comment": "Abolishes cleavage of substrate oligonucleotides.", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" }, { "database": "PubMed", "id": "20194111", "url": "https://glygen.org/publication/PubMed/20194111" } ] } ] }, { "uniprot_canonical_ac": "P31378-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Lys364", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Cannot properly relocalize in response to oxidative stress.", "evidence": [ { "database": "UniProtKB", "id": "P31378", "url": "https://www.uniprot.org/uniprotkb/P31378" }, { "database": "PubMed", "id": "19029246", "url": "https://glygen.org/publication/PubMed/19029246" } ] } ] } ], "record_id": "P31378-1" }, { "uniprot_canonical_ac": "P31380-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1131, "chemical_mass": 128507.0, "gene_names": "FUN30;FUN30;YAL001", "protein_name": "Chromatin remodeling protein FUN30", "disease": [ { "disease_id": "DOID:0050592", "name": "asphyxiating thoracic dystrophy", "description": "A bone development disease characterized by skeletal abnormalities and resulting in difficulty in breathing caused by mutations that result in ciliopathy.", "url": "https://disease-ontology.org/term/DOID:0050592", "evidence": [ { "id": "0050592", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050592" } ], "weight": 0.0 }, { "disease_id": "DOID:0080725", "name": "BASAN syndrome", "description": "An ectodermal dysplasia that is characterized by neonatal blisters and milia and congenital absence of dermatoglyphics on the hands and feet.", "url": "https://disease-ontology.org/term/DOID:0080725", "evidence": [ { "id": "0080725", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080725" } ], "weight": 0.0 }, { "disease_id": "DOID:0111357", "name": "adermatoglyphia", "description": "A skin disease characterized by lack of epidermal ridges on the fingers, toes, palms and soles that has_material_basis_in heterozygous mutation in the SMARCAD1 gene on chromosome 4q22.3.", "url": "https://disease-ontology.org/term/DOID:0111357", "evidence": [ { "id": "0111357", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111357" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of RNA splicing", "id": "GO:0033120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033120", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "rDNA heterochromatin formation", "id": "GO:0000183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000183", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "double-strand break repair involved in meiotic recombination", "id": "GO:1990918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990918", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "meiotic DNA double-strand break processing", "id": "GO:0000706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000706", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "DNA double-strand break processing", "id": "GO:0000729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000729", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "nucleosome array spacer activity", "id": "GO:0140750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140750", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" }, { "name": "mating-type region heterochromatin", "id": "GO:0031934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031934", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31380-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Thr455", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 455, "start_aa": "Thr", "end_pos": 455, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr455", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "1024", "end_pos": "1024", "site_lbl": "Ser1024", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "1025", "end_pos": "1025", "site_lbl": "Thr1025", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "1103", "end_pos": "1103", "site_lbl": "Ser1103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "1124", "end_pos": "1124", "site_lbl": "Ser1124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Thr131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Thr18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Ser232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Thr36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Ser375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Ser376", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Ser383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Thr450", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "451", "end_pos": "451", "site_lbl": "Ser451", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "567", "end_pos": "567", "site_lbl": "Ser567", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Ser86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Thr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31380", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31380" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "SGD", "id": "S000000017", "url": "https://www.yeastgenome.org/locus/S000000017" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31380-1", "start_pos": "603", "end_pos": "603", "site_lbl": "Lys603", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of marker silencing in HMR, the silent mating-type locus. Abolishes both the silencing function and the ability to promote DNA end resection of double-strand breaks (DSBs).", "evidence": [ { "database": "UniProtKB", "id": "P31380", "url": "https://www.uniprot.org/uniprotkb/P31380" }, { "database": "PubMed", "id": "19956593", "url": "https://glygen.org/publication/PubMed/19956593" }, { "database": "PubMed", "id": "22960744", "url": "https://glygen.org/publication/PubMed/22960744" } ] } ] } ], "record_id": "P31380-1" }, { "uniprot_canonical_ac": "P31382-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 759, "chemical_mass": 86870.0, "gene_names": "PMT2;FUN25;PMT2", "protein_name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 2", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:0050560", "name": "Walker-Warburg syndrome", "description": "A congenital muscular dystrophy that is characterized by hypotonia, seizures, severe intellectual and developmental disability, eye abnormalities and early death and has_material_basis_in mutations in multiple genes including POMT1, POMT2, ISPD, FKTN, FKRP, and LARGE1.", "url": "https://disease-ontology.org/term/DOID:0050560", "evidence": [ { "id": "0050560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050560" } ], "weight": 0.0 }, { "disease_id": "DOID:0110274", "name": "autosomal recessive limb-girdle muscular dystrophy", "description": "A limb-girdle muscular dystrophy has_material_basis_in autosomal recessive inheritance.", "url": "https://disease-ontology.org/term/DOID:0110274", "evidence": [ { "id": "0110274", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110274" } ], "weight": 0.0 }, { "disease_id": "DOID:0110298", "name": "autosomal recessive limb-girdle muscular dystrophy type 2N", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the POMT2 gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0110298", "evidence": [ { "id": "0110298", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110298" } ], "weight": 0.0 }, { "disease_id": "DOID:0111240", "name": "congenital muscular dystrophy-dystroglycanopathy type A2", "description": "A congenital muscular dystrophy-dystroglycanopathy type A that has_material_basis_in homozygous or compound heterozygous mutation in POMT2 on 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0111240", "evidence": [ { "id": "0111240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111240" } ], "weight": 0.0 }, { "disease_id": "DOID:0112374", "name": "muscular dystrophy-dystroglycanopathy", "description": "A congenital muscular dystrophy characterized by muscular dystrophy resulting from defective glycosylation of dystroglycan.", "url": "https://disease-ontology.org/term/DOID:0112374", "evidence": [ { "id": "0112374", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112374" } ], "weight": 0.0 }, { "disease_id": "DOID:0112380", "name": "muscular dystrophy-dystroglycanopathy type B2", "description": "A muscular dystrophy-dystroglycanopathy type B that has_material_basis_in homozygous or compound heterozygous mutation in the POMT2 gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0112380", "evidence": [ { "id": "0112380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112380" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase activity", "id": "GO:0004169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004169", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" }, { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex", "id": "GO:0097582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097582", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" }, { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex", "id": "GO:0097584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097584", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" } ], "biological_process": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" }, { "name": "protein exit from endoplasmic reticulum", "id": "GO:0032527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032527", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" }, { "name": "regulation of endoplasmic reticulum unfolded protein response", "id": "GO:1900101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900101", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" }, { "name": "fungal-type cell wall biogenesis", "id": "GO:0009272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009272", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31382-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Asn131", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 131, "start_aa": "Asn", "end_pos": 131, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn131", "evidence": [ { "id": "P31382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P31382#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Asn155", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 155, "start_aa": "Asn", "end_pos": 155, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn155", "evidence": [ { "id": "P31382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P31382#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Asn403", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 403, "start_aa": "Asn", "end_pos": 403, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn403", "evidence": [ { "id": "P31382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P31382#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000021", "url": "https://www.yeastgenome.org/locus/S000000021" }, { "database": "iPTMnet", "id": "P31382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31382" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31382" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000021", "url": "https://www.yeastgenome.org/locus/S000000021" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31382" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000021", "url": "https://www.yeastgenome.org/locus/S000000021" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P31382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31382" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000021", "url": "https://www.yeastgenome.org/locus/S000000021" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31382" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000021", "url": "https://www.yeastgenome.org/locus/S000000021" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P31382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31382" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000021", "url": "https://www.yeastgenome.org/locus/S000000021" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31382", "url": "https://www.uniprot.org/uniprotkb/P31382" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P31382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31382" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000021", "url": "https://www.yeastgenome.org/locus/S000000021" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000021", "url": "https://www.yeastgenome.org/locus/S000000021" }, { "database": "iPTMnet", "id": "P31382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31382" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31382-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000021", "url": "https://www.yeastgenome.org/locus/S000000021" }, { "database": "iPTMnet", "id": "P31382", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31382" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P31382-1" }, { "uniprot_canonical_ac": "P31383-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 635, "chemical_mass": 70907.0, "gene_names": "TPD3;FUN32;TPD3", "protein_name": "Protein phosphatase PP2A regulatory subunit A", "disease": [ { "disease_id": "DOID:0070066", "name": "autosomal dominant intellectual developmental disorder 36", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the PPP2R1A gene on chromosome 19q13.41.", "url": "https://disease-ontology.org/term/DOID:0070066", "evidence": [ { "id": "0070066", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070066" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" }, { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" }, { "name": "meiotic sister chromatid cohesion, centromeric", "id": "GO:0051754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051754", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "P31383", "url": "https://www.uniprot.org/uniprotkb/P31383" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31383-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Thr17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000014", "url": "https://www.yeastgenome.org/locus/S000000014" }, { "database": "iPTMnet", "id": "P31383", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31383" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31383-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000014", "url": "https://www.yeastgenome.org/locus/S000000014" }, { "database": "iPTMnet", "id": "P31383", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31383" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31383-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000014", "url": "https://www.yeastgenome.org/locus/S000000014" }, { "database": "iPTMnet", "id": "P31383", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31383" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31383-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Thr8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000014", "url": "https://www.yeastgenome.org/locus/S000000014" }, { "database": "iPTMnet", "id": "P31383", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31383" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P31383-1" }, { "uniprot_canonical_ac": "P31385-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 405, "chemical_mass": 46978.0, "gene_names": "DEP1;DEP1;FUN54", "protein_name": "Transcriptional regulatory protein DEP1", "disease": [], "biological_process": [ { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylcholine biosynthetic process", "id": "GO:2001247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001247", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "negative regulation of rDNA heterochromatin formation", "id": "GO:0061188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061188", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylcholine biosynthetic process", "id": "GO:2001246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001246", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "negative regulation of inositol biosynthetic process", "id": "GO:1900089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900089", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "negative regulation of silent mating-type cassette heterochromatin formation", "id": "GO:0061186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061186", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "positive regulation of inositol biosynthetic process", "id": "GO:1900090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900090", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylserine biosynthetic process", "id": "GO:1900469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900469", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylserine biosynthetic process", "id": "GO:1900470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900470", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "Rpd3L-Expanded complex", "id": "GO:0070210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070210", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" }, { "name": "Rpd3L complex", "id": "GO:0033698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033698", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31385-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000011", "url": "https://www.yeastgenome.org/locus/S000000011" }, { "database": "iPTMnet", "id": "P31385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31385" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31385-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P31385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31385" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000011", "url": "https://www.yeastgenome.org/locus/S000000011" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31385-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31385" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000011", "url": "https://www.yeastgenome.org/locus/S000000011" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31385-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31385" }, { "database": "SGD", "id": "S000000011", "url": "https://www.yeastgenome.org/locus/S000000011" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31385-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Thr51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000011", "url": "https://www.yeastgenome.org/locus/S000000011" }, { "database": "iPTMnet", "id": "P31385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31385" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31385-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31385", "url": "https://www.uniprot.org/uniprotkb/P31385" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P31385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31385" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000011", "url": "https://www.yeastgenome.org/locus/S000000011" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31385-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000011", "url": "https://www.yeastgenome.org/locus/S000000011" }, { "database": "iPTMnet", "id": "P31385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31385" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31385-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31385" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000011", "url": "https://www.yeastgenome.org/locus/S000000011" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P31385-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Thr82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000011", "url": "https://www.yeastgenome.org/locus/S000000011" }, { "database": "iPTMnet", "id": "P31385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31385" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P31385-1" }, { "uniprot_canonical_ac": "P31539-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 908, "chemical_mass": 102035.0, "gene_names": "HSP104;HSP104;L0948", "protein_name": "Heat shock protein 104", "disease": [ { "disease_id": "DOID:0050590", "name": "severe congenital neutropenia", "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.", "url": "https://disease-ontology.org/term/DOID:0050590", "evidence": [ { "id": "0050590", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050590" } ], "weight": 0.0 }, { "disease_id": "DOID:0081133", "name": "3-methylglutaconic aciduria type 7a", "description": "A 3-methylglutaconic aciduria that is characterized primarily by increased levels of 3-methylglutaconic acid (3-MGA) associated with variable neurologic deficits and neutropenia and that has_material_basis_in heterozygous dominant-negative mutation in the CLPB gene on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0081133", "evidence": [ { "id": "0081133", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081133" } ], "weight": 0.0 }, { "disease_id": "DOID:0081134", "name": "3-methylglutaconic aciduria type 7b", "description": "A 3-methylglutaconic aciduria that has_material_basis_in homozygous or compound heterozygous loss-of-function mutations in the CLPB gene on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0081134", "evidence": [ { "id": "0081134", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081134" } ], "weight": 0.0 } ], "biological_process": [ { "name": "post-translational protein targeting to endoplasmic reticulum membrane", "id": "GO:0006620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006620", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "protein unfolding", "id": "GO:0043335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043335", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "protein folding in endoplasmic reticulum", "id": "GO:0034975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034975", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "stress granule disassembly", "id": "GO:0035617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035617", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "cellular heat acclimation", "id": "GO:0070370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070370", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "trehalose metabolic process", "id": "GO:0005991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005991", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "ADP binding", "id": "GO:0043531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043531", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" }, { "name": "TRC complex", "id": "GO:0072380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072380", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31539-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 5, "start_aa": "Thr", "end_pos": 5, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr5", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P31539", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P31539" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Thr8", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 8, "start_aa": "Thr", "end_pos": 8, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr8", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P31539", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P31539" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Thr162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Thr236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Thr317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Reduces rate of ATP hydrolysis at NBD1 nearly 10-fold. No effect on oligomerization.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "11782421", "url": "https://glygen.org/publication/PubMed/11782421" }, { "database": "PubMed", "id": "17259993", "url": "https://glygen.org/publication/PubMed/17259993" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Ser439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "440", "end_pos": "440", "site_lbl": "Thr440", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "454", "end_pos": "454", "site_lbl": "Ser454", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "499", "end_pos": "499", "site_lbl": "Thr499", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "I", "comment": "Reduces ATP hydrolysis by 50%. Alters bud morphology and causes septin mislocalization; when associated with S-217.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "14978213", "url": "https://glygen.org/publication/PubMed/14978213" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "535", "end_pos": "535", "site_lbl": "Ser535", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "547", "end_pos": "547", "site_lbl": "Ser547", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "562", "end_pos": "562", "site_lbl": "Ser562", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Ser564", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Ser577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "578", "end_pos": "578", "site_lbl": "Ser578", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "597", "end_pos": "597", "site_lbl": "Ser597", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Ser599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "609", "end_pos": "609", "site_lbl": "Ser609", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "644", "end_pos": "644", "site_lbl": "Ser644", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "768", "end_pos": "768", "site_lbl": "Ser768", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "864", "end_pos": "864", "site_lbl": "Ser864", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Thr87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "891", "end_pos": "891", "site_lbl": "Thr891", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "900", "end_pos": "900", "site_lbl": "Ser900", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31539", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31539" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003949", "url": "https://www.yeastgenome.org/locus/S000003949" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Asp184", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Confers resistance to prion-curing by guanidine.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "12105276", "url": "https://glygen.org/publication/PubMed/12105276" } ] }, { "sequence_org": "D", "sequence_mut": "D", "comment": "Confers resistance to prion-curing by guanidine.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "12105276", "url": "https://glygen.org/publication/PubMed/12105276" } ] }, { "sequence_org": "D", "sequence_mut": "F", "comment": "Confers resistance to prion-curing by guanidine.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "12105276", "url": "https://glygen.org/publication/PubMed/12105276" } ] }, { "sequence_org": "D", "sequence_mut": "K", "comment": "Impairs prion propagation.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "12105276", "url": "https://glygen.org/publication/PubMed/12105276" } ] }, { "sequence_org": "D", "sequence_mut": "L", "comment": "Confers resistance to prion-curing by guanidine.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "12105276", "url": "https://glygen.org/publication/PubMed/12105276" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Confers resistance to prion-curing by guanidine.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "12105276", "url": "https://glygen.org/publication/PubMed/12105276" } ] }, { "sequence_org": "D", "sequence_mut": "Q", "comment": "Confers resistance to prion-curing by guanidine.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "12105276", "url": "https://glygen.org/publication/PubMed/12105276" } ] }, { "sequence_org": "D", "sequence_mut": "S", "comment": "Confers resistance to prion-curing by guanidine.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "12105276", "url": "https://glygen.org/publication/PubMed/12105276" } ] }, { "sequence_org": "D", "sequence_mut": "W", "comment": "Impairs prion propagation.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "12105276", "url": "https://glygen.org/publication/PubMed/12105276" } ] }, { "sequence_org": "D", "sequence_mut": "Y", "comment": "Impairs prion propagation.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "12105276", "url": "https://glygen.org/publication/PubMed/12105276" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Gly217", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "Largely reduces ATP hydrolysis. Alters bud morphology and causes septin mislocalization; when associated with I-499.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "11158570", "url": "https://glygen.org/publication/PubMed/11158570" }, { "database": "PubMed", "id": "14978213", "url": "https://glygen.org/publication/PubMed/14978213" }, { "database": "PubMed", "id": "9624144", "url": "https://glygen.org/publication/PubMed/9624144" } ] }, { "sequence_org": "G", "sequence_mut": "V", "comment": "Completely abolishes ATP hydrolysis.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "11158570", "url": "https://glygen.org/publication/PubMed/11158570" }, { "database": "PubMed", "id": "14978213", "url": "https://glygen.org/publication/PubMed/14978213" }, { "database": "PubMed", "id": "9624144", "url": "https://glygen.org/publication/PubMed/9624144" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Lys218", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "T", "comment": "Abolishes substrate binding. Unable to confer thermotolerance. Reduces ATP hydrolysis by 98%; when associated with T-315. Completely abolishes ATPase activity; when associated with T-620.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "8308017", "url": "https://glygen.org/publication/PubMed/8308017" }, { "database": "PubMed", "id": "16135516", "url": "https://glygen.org/publication/PubMed/16135516" }, { "database": "PubMed", "id": "11158570", "url": "https://glygen.org/publication/PubMed/11158570" }, { "database": "PubMed", "id": "17543332", "url": "https://glygen.org/publication/PubMed/17543332" }, { "database": "PubMed", "id": "11442834", "url": "https://glygen.org/publication/PubMed/11442834" }, { "database": "PubMed", "id": "12101251", "url": "https://glygen.org/publication/PubMed/12101251" }, { "database": "PubMed", "id": "11983167", "url": "https://glygen.org/publication/PubMed/11983167" }, { "database": "PubMed", "id": "1896074", "url": "https://glygen.org/publication/PubMed/1896074" }, { "database": "PubMed", "id": "17259993", "url": "https://glygen.org/publication/PubMed/17259993" }, { "database": "PubMed", "id": "9624144", "url": "https://glygen.org/publication/PubMed/9624144" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Tyr257", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Reduces thermotolerance 10-fold.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "15128736", "url": "https://glygen.org/publication/PubMed/15128736" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Glu285", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "In HSP104(TRAP); completely abolishes ATP hydrolysis, but does not affect nucleotide binding, thus keeping HSP104 in an ATP-bound state; when associated with Q-687.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "16135516", "url": "https://glygen.org/publication/PubMed/16135516" }, { "database": "PubMed", "id": "17543332", "url": "https://glygen.org/publication/PubMed/17543332" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Ala315", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "T", "comment": "Reduces ATP hydrolysis by 98%; when associated with T-218.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "11983167", "url": "https://glygen.org/publication/PubMed/11983167" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Arg334", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "M", "comment": "Reduces ATPase activity by 80%. Impairs oligomerization.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "18160044", "url": "https://glygen.org/publication/PubMed/18160044" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Arg419", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "M", "comment": "Reduces ATPase activity by 80%.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "18160044", "url": "https://glygen.org/publication/PubMed/18160044" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "444", "end_pos": "444", "site_lbl": "Arg444", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "M", "comment": "Reduces ATPase activity by 80%.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "18160044", "url": "https://glygen.org/publication/PubMed/18160044" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "462", "end_pos": "462", "site_lbl": "Leu462", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "R", "comment": "Impairs prion propagation, but does not affect thermotolerance.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "17367387", "url": "https://glygen.org/publication/PubMed/17367387" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Arg495", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "M", "comment": "Increases ATPase activity 3-fold.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "18160044", "url": "https://glygen.org/publication/PubMed/18160044" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Ala503", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "V", "comment": "Increases basal level of ATPase activity and abolishes stimulation of ATP hydrolysis upon substrate binding. Inhibits growth at 37 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "11983167", "url": "https://glygen.org/publication/PubMed/11983167" }, { "database": "PubMed", "id": "14978213", "url": "https://glygen.org/publication/PubMed/14978213" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "509", "end_pos": "509", "site_lbl": "Ala509", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "D", "comment": "Reduces thermotolerance.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "14978213", "url": "https://glygen.org/publication/PubMed/14978213" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "557", "end_pos": "557", "site_lbl": "Pro557", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "Impairs prion propagation, but does not affect thermotolerance.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "17367387", "url": "https://glygen.org/publication/PubMed/17367387" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "619", "end_pos": "619", "site_lbl": "Gly619", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "V", "comment": "Impairs oligomerization at low protein concentrations.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "11158570", "url": "https://glygen.org/publication/PubMed/11158570" }, { "database": "PubMed", "id": "9624144", "url": "https://glygen.org/publication/PubMed/9624144" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Lys620", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "T", "comment": "Impairs oligomerization at low protein concentrations. Reduces ATP hydrolysis rate. Unable to confer thermotolerance. Completely abolishes ATPase activity; when associated with T-218.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "8308017", "url": "https://glygen.org/publication/PubMed/8308017" }, { "database": "PubMed", "id": "16135516", "url": "https://glygen.org/publication/PubMed/16135516" }, { "database": "PubMed", "id": "11158570", "url": "https://glygen.org/publication/PubMed/11158570" }, { "database": "PubMed", "id": "17543332", "url": "https://glygen.org/publication/PubMed/17543332" }, { "database": "PubMed", "id": "11442834", "url": "https://glygen.org/publication/PubMed/11442834" }, { "database": "PubMed", "id": "12101251", "url": "https://glygen.org/publication/PubMed/12101251" }, { "database": "PubMed", "id": "1896074", "url": "https://glygen.org/publication/PubMed/1896074" }, { "database": "PubMed", "id": "17259993", "url": "https://glygen.org/publication/PubMed/17259993" }, { "database": "PubMed", "id": "9624144", "url": "https://glygen.org/publication/PubMed/9624144" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Thr621", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Reduces ATP hydrolysis, but does not affect oligomerization.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "11158570", "url": "https://glygen.org/publication/PubMed/11158570" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "645", "end_pos": "645", "site_lbl": "Glu645", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Abolishes the ability to refold aggregated protein in vitro and to provide thermotolerance in vivo.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "15128736", "url": "https://glygen.org/publication/PubMed/15128736" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "662", "end_pos": "662", "site_lbl": "Tyr662", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes the ability to refold aggregated protein in vitro and to provide thermotolerance in vivo.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "15128736", "url": "https://glygen.org/publication/PubMed/15128736" } ] }, { "sequence_org": "Y", "sequence_mut": "F", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "15128736", "url": "https://glygen.org/publication/PubMed/15128736" } ] }, { "sequence_org": "Y", "sequence_mut": "K", "comment": "Abolishes the ability to refold aggregated protein in vitro and to provide thermotolerance in vivo.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "15128736", "url": "https://glygen.org/publication/PubMed/15128736" } ] }, { "sequence_org": "Y", "sequence_mut": "W", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "15128736", "url": "https://glygen.org/publication/PubMed/15128736" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "687", "end_pos": "687", "site_lbl": "Glu687", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "In HSP104(TRAP); completely abolishes ATP hydrolysis, but does not affect nucleotide binding, thus keeping HSP104 in an ATP-bound state; when associated with Q-285.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "16135516", "url": "https://glygen.org/publication/PubMed/16135516" }, { "database": "PubMed", "id": "17543332", "url": "https://glygen.org/publication/PubMed/17543332" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "704", "end_pos": "704", "site_lbl": "Asp704", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Impairs prion propagation, but does not affect thermotolerance.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "17367387", "url": "https://glygen.org/publication/PubMed/17367387" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "728", "end_pos": "728", "site_lbl": "Asn728", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Almost completely abolishes ATP hydrolysis at NBD2, but does not affect nucleotide binding, thus keeping NBD2 in an ATP-bound state. Reduces stimulation of ATP hydrolysis upon substrate binding.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "18160044", "url": "https://glygen.org/publication/PubMed/18160044" }, { "database": "PubMed", "id": "11983167", "url": "https://glygen.org/publication/PubMed/11983167" }, { "database": "PubMed", "id": "11782421", "url": "https://glygen.org/publication/PubMed/11782421" }, { "database": "PubMed", "id": "17259993", "url": "https://glygen.org/publication/PubMed/17259993" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "765", "end_pos": "765", "site_lbl": "Arg765", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "M", "comment": "Can oligomerize in the absence of nucleotides.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "18160044", "url": "https://glygen.org/publication/PubMed/18160044" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "778", "end_pos": "778", "site_lbl": "Lys778", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In NLS17KA; fails to concentrate in the nucleus; when associated with A-782 and A-789.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "17973656", "url": "https://glygen.org/publication/PubMed/17973656" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "782", "end_pos": "782", "site_lbl": "Lys782", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In NLS17KA; fails to concentrate in the nucleus; when associated with A-778 and A-789.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "17973656", "url": "https://glygen.org/publication/PubMed/17973656" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "789", "end_pos": "789", "site_lbl": "Lys789", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In NLS17KA; fails to concentrate in the nucleus; when associated with A-778 and A-782.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "17973656", "url": "https://glygen.org/publication/PubMed/17973656" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "819", "end_pos": "819", "site_lbl": "Tyr819", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "W", "comment": "Site-specific fluorescent probe in an otherwise Trp-less HSP104. Fluorescence of this Trp changes in response to ATP and ADP binding at NBD2. Has no effect on ATP hydrolysis or protein stability.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "11867765", "url": "https://glygen.org/publication/PubMed/11867765" } ] } ] }, { "uniprot_canonical_ac": "P31539-1", "start_pos": "826", "end_pos": "826", "site_lbl": "Arg826", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "M", "comment": "Reduces ATP and ADP binding at NBD2 6-fold, but does not affect ATP hydrolysis at NBD2. Reduces catalytic rate at NBD1.", "evidence": [ { "database": "UniProtKB", "id": "P31539", "url": "https://www.uniprot.org/uniprotkb/P31539" }, { "database": "PubMed", "id": "11867765", "url": "https://glygen.org/publication/PubMed/11867765" } ] } ] } ], "record_id": "P31539-1" }, { "uniprot_canonical_ac": "P31688-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31688", "url": "https://www.uniprot.org/uniprotkb/P31688" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 896, "chemical_mass": 102976.0, "gene_names": "TPS2;HOG2;PFK3;TPS2;YD8554.07", "protein_name": "Trehalose-phosphatase", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P31688", "url": "https://www.uniprot.org/uniprotkb/P31688" } ], "pmid": "" }, { "name": "alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)", "id": "GO:0005946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005946", "evidence": [ { "database": "UniProtKB", "id": "P31688", "url": "https://www.uniprot.org/uniprotkb/P31688" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "P31688", "url": "https://www.uniprot.org/uniprotkb/P31688" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "P31688", "url": "https://www.uniprot.org/uniprotkb/P31688" } ], "pmid": "" }, { "name": "trehalose metabolic process", "id": "GO:0005991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005991", "evidence": [ { "database": "UniProtKB", "id": "P31688", "url": "https://www.uniprot.org/uniprotkb/P31688" } ], "pmid": "" }, { "name": "trehalose biosynthetic process", "id": "GO:0005992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005992", "evidence": [ { "database": "UniProtKB", "id": "P31688", "url": "https://www.uniprot.org/uniprotkb/P31688" } ], "pmid": "" } ], "molecular_function": [ { "name": "trehalose-phosphatase activity", "id": "GO:0004805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004805", "evidence": [ { "database": "UniProtKB", "id": "P31688", "url": "https://www.uniprot.org/uniprotkb/P31688" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31688-1", "start_pos": "819", "end_pos": "819", "site_lbl": "Thr819", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 819, "start_aa": "Thr", "end_pos": 819, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr819", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Ser264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Ser515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "554", "end_pos": "554", "site_lbl": "Thr554", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "583", "end_pos": "583", "site_lbl": "Thr583", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "638", "end_pos": "638", "site_lbl": "Ser638", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "822", "end_pos": "822", "site_lbl": "Ser822", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "824", "end_pos": "824", "site_lbl": "Ser824", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "863", "end_pos": "863", "site_lbl": "Ser863", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "870", "end_pos": "870", "site_lbl": "Ser870", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "873", "end_pos": "873", "site_lbl": "Ser873", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "876", "end_pos": "876", "site_lbl": "Ser876", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "888", "end_pos": "888", "site_lbl": "Ser888", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "890", "end_pos": "890", "site_lbl": "Ser890", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "891", "end_pos": "891", "site_lbl": "Tyr891", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "892", "end_pos": "892", "site_lbl": "Thr892", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P31688-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002481", "url": "https://www.yeastgenome.org/locus/S000002481" }, { "database": "iPTMnet", "id": "P31688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P31688" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P31688-1" }, { "uniprot_canonical_ac": "P31755-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P31755", "url": "https://www.uniprot.org/uniprotkb/P31755" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 480, "chemical_mass": 55156.0, "gene_names": "OCH1;LDB12;NGD29;OCH1", "protein_name": "Initiation-specific alpha-1,6-mannosyltransferase", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P31755", "url": "https://www.uniprot.org/uniprotkb/P31755" } ], "pmid": "" }, { "name": "Golgi cis cisterna", "id": "GO:0000137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000137", "evidence": [ { "database": "UniProtKB", "id": "P31755", "url": "https://www.uniprot.org/uniprotkb/P31755" } ], "pmid": "" }, { "name": "mannan polymerase complex", "id": "GO:0000136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000136", "evidence": [ { "database": "UniProtKB", "id": "P31755", "url": "https://www.uniprot.org/uniprotkb/P31755" } ], "pmid": "" } ], "biological_process": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "P31755", "url": "https://www.uniprot.org/uniprotkb/P31755" } ], "pmid": "" } ], "molecular_function": [ { "name": "alpha-1,6-mannosyltransferase activity", "id": "GO:0000009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000009", "evidence": [ { "database": "UniProtKB", "id": "P31755", "url": "https://www.uniprot.org/uniprotkb/P31755" } ], "pmid": "" }, { "name": "initiation-specific glycolipid 1,6-alpha-mannosyltransferase activity", "id": "GO:0033164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033164", "evidence": [ { "database": "UniProtKB", "id": "P31755", "url": "https://www.uniprot.org/uniprotkb/P31755" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P31755-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Asn203", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 203, "start_aa": "Asn", "end_pos": 203, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn203", "evidence": [ { "id": "P31755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P31755#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P31755-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Asn281", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 281, "start_aa": "Asn", "end_pos": 281, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn281", "evidence": [ { "id": "P31755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P31755#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P31755-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Asn341", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 341, "start_aa": "Asn", "end_pos": 341, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn341", "evidence": [ { "id": "P31755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P31755#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P31755-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Asn393", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 393, "start_aa": "Asn", "end_pos": 393, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn393", "evidence": [ { "id": "P31755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P31755#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P31755-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Asp187", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of mannosyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P31755", "url": "https://www.uniprot.org/uniprotkb/P31755" }, { "database": "PubMed", "id": "17042779", "url": "https://glygen.org/publication/PubMed/17042779" } ] } ] } ], "record_id": "P31755-1" }, { "uniprot_canonical_ac": "P32178-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 256, "chemical_mass": 29747.0, "gene_names": "ARO7;ARO7;HGS1;OSM2;TYR7;YP9499.15C", "protein_name": "Chorismate mutase", "disease": [], "biological_process": [ { "name": "tyrosine biosynthetic process", "id": "GO:0006571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006571", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" } ], "pmid": "" }, { "name": "chorismate metabolic process", "id": "GO:0046417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046417", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" } ], "pmid": "" }, { "name": "aromatic amino acid family biosynthetic process", "id": "GO:0009073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009073", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" } ], "pmid": "" }, { "name": "L-phenylalanine biosynthetic process", "id": "GO:0009094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009094", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" } ], "pmid": "" } ], "molecular_function": [ { "name": "L-tyrosine binding", "id": "GO:0072545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072545", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" } ], "pmid": "" }, { "name": "chorismate mutase activity", "id": "GO:0004106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004106", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" } ], "pmid": "" }, { "name": "tryptophan binding", "id": "GO:0120284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120284", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32178-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006264", "url": "https://www.yeastgenome.org/locus/S000006264" }, { "database": "iPTMnet", "id": "P32178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32178" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32178-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006264", "url": "https://www.yeastgenome.org/locus/S000006264" }, { "database": "iPTMnet", "id": "P32178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32178" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32178-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006264", "url": "https://www.yeastgenome.org/locus/S000006264" }, { "database": "iPTMnet", "id": "P32178", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32178" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32178-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Gly141", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "Abolishes tyrosine and tryptophan binding, resulting in loss of enzyme activity regulation by effectors.", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" }, { "database": "PubMed", "id": "9642265", "url": "https://glygen.org/publication/PubMed/9642265" } ] } ] }, { "uniprot_canonical_ac": "P32178-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Decreases tyrosine and tryptophan binding, resulting in attenuated enzyme activity regulation by effectors.", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" }, { "database": "PubMed", "id": "9642265", "url": "https://glygen.org/publication/PubMed/9642265" } ] } ] }, { "uniprot_canonical_ac": "P32178-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Thr145", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "V", "comment": "Decreases tyrosine binding, resulting in loss of enzyme inhibition by tyrosine. Enhances activation by phenylalanine.", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" }, { "database": "PubMed", "id": "9642265", "url": "https://glygen.org/publication/PubMed/9642265" } ] } ] }, { "uniprot_canonical_ac": "P32178-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Thr226", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "D", "comment": "Constitutively inactive. Unresponsive to tryptophan activation.", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" }, { "database": "PubMed", "id": "10428795", "url": "https://glygen.org/publication/PubMed/10428795" } ] }, { "sequence_org": "T", "sequence_mut": "I", "comment": "Constitutively active. Unresponsive to tryptophan activation and tyrosine feedback inhibition.", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" }, { "database": "PubMed", "id": "2187528", "url": "https://glygen.org/publication/PubMed/2187528" }, { "database": "PubMed", "id": "2646272", "url": "https://glygen.org/publication/PubMed/2646272" }, { "database": "PubMed", "id": "10428795", "url": "https://glygen.org/publication/PubMed/10428795" } ] } ] }, { "uniprot_canonical_ac": "P32178-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Arg75", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Severely decreases tyrosine and tryptophan binding, resulting in loss of enzyme activity regulation by effectors.", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" }, { "database": "PubMed", "id": "9642265", "url": "https://glygen.org/publication/PubMed/9642265" } ] } ] }, { "uniprot_canonical_ac": "P32178-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Arg76", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Severely decreases tyrosine and tryptophan binding, resulting in loss of enzyme activity regulation by effectors.", "evidence": [ { "database": "UniProtKB", "id": "P32178", "url": "https://www.uniprot.org/uniprotkb/P32178" }, { "database": "PubMed", "id": "9642265", "url": "https://glygen.org/publication/PubMed/9642265" } ] } ] } ], "record_id": "P32178-1" }, { "uniprot_canonical_ac": "P32179-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 357, "chemical_mass": 39149.0, "gene_names": "MET22;HAL2;MET22", "protein_name": "3'(2'),5'-bisphosphate nucleotidase", "disease": [], "biological_process": [ { "name": "tRNA decay", "id": "GO:0016078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016078", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" } ], "pmid": "" }, { "name": "hyperosmotic salinity response", "id": "GO:0042538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042538", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" } ], "pmid": "" }, { "name": "methionine biosynthetic process", "id": "GO:0009086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009086", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" } ], "pmid": "" }, { "name": "sulfate assimilation", "id": "GO:0000103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000103", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" } ], "pmid": "" }, { "name": "3'(2'),5'-bisphosphate nucleotidase activity", "id": "GO:0008441", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008441", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32179-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005425", "url": "https://www.yeastgenome.org/locus/S000005425" }, { "database": "iPTMnet", "id": "P32179", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32179" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32179-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005425", "url": "https://www.yeastgenome.org/locus/S000005425" }, { "database": "iPTMnet", "id": "P32179", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32179" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32179-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005425", "url": "https://www.yeastgenome.org/locus/S000005425" }, { "database": "iPTMnet", "id": "P32179", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32179" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32179-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Glu238", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Increases levels of lithium and sodium resistance while maintaining a relatively high specific activity. 5-fold decrease in affinity for PAP.", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" }, { "database": "PubMed", "id": "10656801", "url": "https://glygen.org/publication/PubMed/10656801" } ] } ] }, { "uniprot_canonical_ac": "P32179-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Val70", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Increases levels of lithium and sodium resistance while maintaining a relatively high specific activity. Increases affinity for PAP.", "evidence": [ { "database": "UniProtKB", "id": "P32179", "url": "https://www.uniprot.org/uniprotkb/P32179" }, { "database": "PubMed", "id": "10656801", "url": "https://glygen.org/publication/PubMed/10656801" } ] } ] } ], "record_id": "P32179-1" }, { "uniprot_canonical_ac": "P32259-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 974, "chemical_mass": 111297.0, "gene_names": "SIN4;BEL2;GAL22;MED16;N1135;RYE1;SDI3;SIN4;SSF5;SSN4;SSX3;TSF3", "protein_name": "Mediator of RNA polymerase II transcription subunit 16", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" }, { "name": "regulation of establishment of protein localization to chromosome", "id": "GO:0070202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070202", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "P32259", "url": "https://www.uniprot.org/uniprotkb/P32259" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32259-1", "start_pos": "944", "end_pos": "944", "site_lbl": "Thr944", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 944, "start_aa": "Thr", "end_pos": 944, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr944", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32259", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32259" } ] } ] }, { "uniprot_canonical_ac": "P32259-1", "start_pos": "948", "end_pos": "948", "site_lbl": "Thr948", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 948, "start_aa": "Thr", "end_pos": 948, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr948", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32259", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32259" } ] } ] }, { "uniprot_canonical_ac": "P32259-1", "start_pos": "949", "end_pos": "949", "site_lbl": "Ser949", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 949, "start_aa": "Ser", "end_pos": 949, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser949", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32259", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32259" } ] } ] }, { "uniprot_canonical_ac": "P32259-1", "start_pos": "952", "end_pos": "952", "site_lbl": "Thr952", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 952, "start_aa": "Thr", "end_pos": 952, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr952", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32259", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32259" } ] } ] }, { "uniprot_canonical_ac": "P32259-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Ser431", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005180", "url": "https://www.yeastgenome.org/locus/S000005180" }, { "database": "iPTMnet", "id": "P32259", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32259" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32259-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005180", "url": "https://www.yeastgenome.org/locus/S000005180" }, { "database": "iPTMnet", "id": "P32259", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32259" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32259-1" }, { "uniprot_canonical_ac": "P32266-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 881, "chemical_mass": 99178.0, "gene_names": "MGM1;MDM17;MGM1;MNA1;YOR50-1", "protein_name": "Dynamin-like GTPase MGM1, mitochondrial", "disease": [ { "disease_id": "DOID:0080336", "name": "mitochondrial DNA depletion syndrome 14", "description": "A mitochondrial DNA depletion syndrome that is characterized by severe lethal infantile mitochondrial encephalomyopathy and hypertrophic cardiomyopathy, with hypotonia and peripheral hypertonia with opisthotonic posturing, as well as feeding difficulties and profound neurodevelopmental delay, and has_material_basis_in homozygous mutation in the OPA1 mitochondrial dynamin like GTPase gene on chromosome 3q29.", "url": "https://disease-ontology.org/term/DOID:0080336", "evidence": [ { "id": "0080336", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080336" } ], "weight": 0.0 }, { "disease_id": "DOID:0111340", "name": "dominant optic atrophy plus syndrome", "description": "A syndrome characterized by visual loss and sensorineural hearing loss with onset in childhood and associated with other symptoms including; progressive external ophthalmoplegia, muscle cramps, hyperreflexia, and ataxia that has_material_basis_in heterozygous mutation in the OPA1 gene on chromosome 3q29.", "url": "https://disease-ontology.org/term/DOID:0111340", "evidence": [ { "id": "0111340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111340" } ], "weight": 0.0 }, { "disease_id": "DOID:0111441", "name": "optic atrophy 1", "description": "An optic atrophy characterized by early childhood onset of visual impairment, temporal optic disc pallor, color vision deficits, and centrocecal scotoma of variable density that has_material_basis_in heterozygous mutation in the OPA1 gene on chromosome 3q29.", "url": "https://disease-ontology.org/term/DOID:0111441", "evidence": [ { "id": "0111441", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111441" } ], "weight": 0.0 }, { "disease_id": "DOID:0111580", "name": "Behr syndrome", "description": "A nervous system disease characterized by early-onset optic atrophy, ataxia, pyramidal signs, spasticity, and intellectual disability that has_material_basis_in homozygous or compound heterozygous mutation in the OPA1 gene on chromosome 3q29.", "url": "https://disease-ontology.org/term/DOID:0111580", "evidence": [ { "id": "0111580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111580" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1070", "name": "primary open angle glaucoma", "description": "An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure.", "url": "https://disease-ontology.org/term/DOID:1070", "evidence": [ { "id": "1070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1070" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.", "url": "https://disease-ontology.org/term/DOID:4483", "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:5723", "name": "optic atrophy", "description": "An optic nerve disease that is characterized the death of the retinal ganglion cell axons that comprise the optic nerve.", "url": "https://disease-ontology.org/term/DOID:5723", "evidence": [ { "id": "5723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5723" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 }, { "disease_id": "DOID:890", "name": "mitochondrial encephalomyopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:890", "evidence": [ { "id": "890", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:890" } ], "weight": 0.0 }, { "disease_id": "DOID:9282", "name": "ocular hypertension", "description": "An eye disease that is characterized by elevated intraocular pressure in the absence of optic nerve damage or visual field loss.", "url": "https://disease-ontology.org/term/DOID:9282", "evidence": [ { "id": "9282", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9282" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 } ], "biological_process": [ { "name": "membrane tubulation", "id": "GO:0097749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097749", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "membrane bending", "id": "GO:0097753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097753", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "heme transport", "id": "GO:0015886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015886", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrial membrane organization", "id": "GO:0007006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007006", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrion inheritance", "id": "GO:0000001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000001", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrial outer membrane fusion", "id": "GO:1990626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990626", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrial inner membrane fusion", "id": "GO:1990627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990627", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "phosphatidic acid binding", "id": "GO:0070300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070300", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "cardiolipin binding", "id": "GO:1901612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901612", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "GTPase-dependent fusogenic activity", "id": "GO:0140523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140523", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "membrane bending activity", "id": "GO:0180020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180020", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrial crista", "id": "GO:0030061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030061", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" }, { "name": "mitochondrial inner boundary membrane", "id": "GO:0097002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097002", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32266-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Ser463", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005737", "url": "https://www.yeastgenome.org/locus/S000005737" }, { "database": "iPTMnet", "id": "P32266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32266" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "1", "end_pos": "1", "site_lbl": "Met1", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "A", "comment": "Abolishes translation.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "7916673", "url": "https://glygen.org/publication/PubMed/7916673" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Lys223", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of stability.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "12566426", "url": "https://glygen.org/publication/PubMed/12566426" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of GTPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "10037792", "url": "https://glygen.org/publication/PubMed/10037792" }, { "database": "PubMed", "id": "12566426", "url": "https://glygen.org/publication/PubMed/12566426" }, { "database": "PubMed", "id": "19752025", "url": "https://glygen.org/publication/PubMed/19752025" }, { "database": "PubMed", "id": "19236101", "url": "https://glygen.org/publication/PubMed/19236101" } ] }, { "sequence_org": "S", "sequence_mut": "N", "comment": "Loss of GTPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "12566426", "url": "https://glygen.org/publication/PubMed/12566426" }, { "database": "PubMed", "id": "10037792", "url": "https://glygen.org/publication/PubMed/10037792" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Pro237", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "In mgm1-8 mutant; temperature-sensitive mutant; impaired fusion of the mitochondrial inner membrane.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "17055438", "url": "https://glygen.org/publication/PubMed/17055438" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Thr244", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Loss of GTPase activity. Abolished GTPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "12566426", "url": "https://glygen.org/publication/PubMed/12566426" }, { "database": "PubMed", "id": "19236101", "url": "https://glygen.org/publication/PubMed/19236101" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Glu294", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "In mdm17; loss of function at 37 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "10037792", "url": "https://glygen.org/publication/PubMed/10037792" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Ser308", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "F", "comment": "In mgm1-6 mutant; temperature-sensitive mutant; impaired fusion of the mitochondrial inner membrane.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "17055438", "url": "https://glygen.org/publication/PubMed/17055438" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Met39", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "A", "comment": "No effect on translation.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "7916673", "url": "https://glygen.org/publication/PubMed/7916673" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "409", "end_pos": "409", "site_lbl": "Gly409", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In mgm1-5 mutant; temperature-sensitive mutant; impaired fusion of the mitochondrial inner membrane.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "17055438", "url": "https://glygen.org/publication/PubMed/17055438" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "520", "end_pos": "520", "site_lbl": "Tyr520", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Dominant negative mutant that induces fragmentation of the mitochondrial network.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "31292547", "url": "https://glygen.org/publication/PubMed/31292547" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Asp542", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Impaired dimerization.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "32041880", "url": "https://glygen.org/publication/PubMed/32041880" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Gly79", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Loss of function; most MGM1 processed to s-MGM1.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "15096522", "url": "https://glygen.org/publication/PubMed/15096522" } ] }, { "sequence_org": "G", "sequence_mut": "K", "comment": "Loss of function; most MGM1 processed to s-MGM1.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "15096522", "url": "https://glygen.org/publication/PubMed/15096522" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "805", "end_pos": "805", "site_lbl": "Phe805", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "D", "comment": "Impaired mitochondrial morphology.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "31292547", "url": "https://glygen.org/publication/PubMed/31292547" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Met81", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "A", "comment": "No effect on translation.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "7916673", "url": "https://glygen.org/publication/PubMed/7916673" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "823", "end_pos": "823", "site_lbl": "Asp823", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "In mgm1-7 mutant; temperature-sensitive mutant; impaired fusion of the mitochondrial inner membrane.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "17055438", "url": "https://glygen.org/publication/PubMed/17055438" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "824", "end_pos": "824", "site_lbl": "Arg824", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Loss of GED function.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "12566426", "url": "https://glygen.org/publication/PubMed/12566426" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "854", "end_pos": "854", "site_lbl": "Lys854", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of GED function. Abolished GTPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "12566426", "url": "https://glygen.org/publication/PubMed/12566426" }, { "database": "PubMed", "id": "19236101", "url": "https://glygen.org/publication/PubMed/19236101" } ] } ] }, { "uniprot_canonical_ac": "P32266-1", "start_pos": "92", "end_pos": "92", "site_lbl": "Met92", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "A", "comment": "No effect on translation.", "evidence": [ { "database": "UniProtKB", "id": "P32266", "url": "https://www.uniprot.org/uniprotkb/P32266" }, { "database": "PubMed", "id": "7916673", "url": "https://glygen.org/publication/PubMed/7916673" } ] } ] } ], "record_id": "P32266-1" }, { "uniprot_canonical_ac": "P32288-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32288", "url": "https://www.uniprot.org/uniprotkb/P32288" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 370, "chemical_mass": 41766.0, "gene_names": "GLN1;GLN1;YP3085.01;YP9367.15", "protein_name": "Glutamine synthetase", "disease": [ { "disease_id": "DOID:0070544", "name": "congenital glutamine deficiency", "description": "An amino acid metabolic disorder characterized by onset at birth of encephalopathy, lack of normal development, seizures, and hypotonia associated with variable brain abnormalities that has_material_basis_in homozygous mutation in the GLUL gene on chromosome 1q25.3.", "url": "https://disease-ontology.org/term/DOID:0070544", "evidence": [ { "id": "0070544", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070544" } ], "weight": 0.0 }, { "disease_id": "DOID:0070545", "name": "developmental and epileptic encephalopathy 116", "description": "A developmental and epileptic encephalopathy characterized by severe developmental delay, seizures, and white matter abnormalities but normal plasma and cerebrospinal fluid biochemistry that has_material_basis_in heterozygous mutation in the GLUL gene on chromosome 1q25.3.", "url": "https://disease-ontology.org/term/DOID:0070545", "evidence": [ { "id": "0070545", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070545" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1070", "name": "primary open angle glaucoma", "description": "An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure.", "url": "https://disease-ontology.org/term/DOID:1070", "evidence": [ { "id": "1070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1070" } ], "weight": 0.0 }, { "disease_id": "DOID:114", "name": "heart disease", "description": "A cardiovascular system disease that involves the heart.", "url": "https://disease-ontology.org/term/DOID:114", "evidence": [ { "id": "114", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:114" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:409", "name": "liver disease", "description": "", "url": "https://disease-ontology.org/term/DOID:409", "evidence": [ { "id": "409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:409" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32288", "url": "https://www.uniprot.org/uniprotkb/P32288" } ], "pmid": "" }, { "name": "glutamine synthetase activity", "id": "GO:0004356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004356", "evidence": [ { "database": "UniProtKB", "id": "P32288", "url": "https://www.uniprot.org/uniprotkb/P32288" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32288", "url": "https://www.uniprot.org/uniprotkb/P32288" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32288", "url": "https://www.uniprot.org/uniprotkb/P32288" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "P32288", "url": "https://www.uniprot.org/uniprotkb/P32288" } ], "pmid": "" } ], "biological_process": [ { "name": "glutamine biosynthetic process", "id": "GO:0006542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006542", "evidence": [ { "database": "UniProtKB", "id": "P32288", "url": "https://www.uniprot.org/uniprotkb/P32288" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32288-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Ser275", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006239", "url": "https://www.yeastgenome.org/locus/S000006239" }, { "database": "iPTMnet", "id": "P32288", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32288" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32288-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Ser287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006239", "url": "https://www.yeastgenome.org/locus/S000006239" }, { "database": "iPTMnet", "id": "P32288", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32288" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32288-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Ser301", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006239", "url": "https://www.yeastgenome.org/locus/S000006239" }, { "database": "iPTMnet", "id": "P32288", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32288" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32288-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006239", "url": "https://www.yeastgenome.org/locus/S000006239" }, { "database": "iPTMnet", "id": "P32288", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32288" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32288-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Ser315", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006239", "url": "https://www.yeastgenome.org/locus/S000006239" }, { "database": "iPTMnet", "id": "P32288", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32288" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32288-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006239", "url": "https://www.yeastgenome.org/locus/S000006239" }, { "database": "iPTMnet", "id": "P32288", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32288" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32288-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006239", "url": "https://www.yeastgenome.org/locus/S000006239" }, { "database": "iPTMnet", "id": "P32288", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32288" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32288-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32288", "url": "https://www.uniprot.org/uniprotkb/P32288" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P32288", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32288" }, { "database": "SGD", "id": "S000006239", "url": "https://www.yeastgenome.org/locus/S000006239" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32288-1" }, { "uniprot_canonical_ac": "P32316-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32316", "url": "https://www.uniprot.org/uniprotkb/P32316" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 526, "chemical_mass": 58712.0, "gene_names": "ACH1;ACH1;YBL03.18;YBL0304", "protein_name": "Acetyl-CoA hydrolase", "disease": [], "biological_process": [ { "name": "acetate metabolic process", "id": "GO:0006083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006083", "evidence": [ { "database": "UniProtKB", "id": "P32316", "url": "https://www.uniprot.org/uniprotkb/P32316" } ], "pmid": "" } ], "molecular_function": [ { "name": "acetyl-CoA hydrolase activity", "id": "GO:0003986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003986", "evidence": [ { "database": "UniProtKB", "id": "P32316", "url": "https://www.uniprot.org/uniprotkb/P32316" } ], "pmid": "" }, { "name": "acetate CoA-transferase activity", "id": "GO:0008775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008775", "evidence": [ { "database": "UniProtKB", "id": "P32316", "url": "https://www.uniprot.org/uniprotkb/P32316" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32316", "url": "https://www.uniprot.org/uniprotkb/P32316" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32316", "url": "https://www.uniprot.org/uniprotkb/P32316" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32316-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Thr183", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 183, "start_aa": "Thr", "end_pos": 183, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr183", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32316-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Thr241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000111", "url": "https://www.yeastgenome.org/locus/S000000111" }, { "database": "iPTMnet", "id": "P32316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32316" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32316-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Ser350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32316", "url": "https://www.uniprot.org/uniprotkb/P32316" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P32316", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32316" }, { "database": "SGD", "id": "S000000111", "url": "https://www.yeastgenome.org/locus/S000000111" } ] } ] } ], "record_id": "P32316-1" }, { "uniprot_canonical_ac": "P32318-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 326, "chemical_mass": 34991.0, "gene_names": "THI4;ESP35;G6620;MOL1;THI4", "protein_name": "Thiamine thiazole synthase", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" } ], "pmid": "" }, { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" } ], "pmid": "" }, { "name": "cysteine-dependent adenosine diphosphate thiazole synthase activity", "id": "GO:0160205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160205", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" } ], "pmid": "" } ], "biological_process": [ { "name": "thiazole biosynthetic process", "id": "GO:0052837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052837", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" } ], "pmid": "" }, { "name": "thiamine biosynthetic process", "id": "GO:0009228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009228", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32318-1", "start_pos": "200", "end_pos": "200", "site_lbl": "His200", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "N", "comment": "Partially active, trapping the enzyme at an advanced intermediate, just before the sulfide transfer reaction.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] } ] }, { "uniprot_canonical_ac": "P32318-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Cys204", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Partially active, trapping the enzyme at an advanced intermediate, just before the sulfide transfer reaction.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] } ] }, { "uniprot_canonical_ac": "P32318-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Cys205", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Partially active, with very weak activity toward NAD.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] } ] }, { "uniprot_canonical_ac": "P32318-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Asp207", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "No activity.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] } ] }, { "uniprot_canonical_ac": "P32318-1", "start_pos": "237", "end_pos": "237", "site_lbl": "His237", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "No activity.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] }, { "sequence_org": "H", "sequence_mut": "N", "comment": "No activity.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] } ] }, { "uniprot_canonical_ac": "P32318-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Asp238", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Partially active, with very weak activity toward NAD.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] } ] }, { "uniprot_canonical_ac": "P32318-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Arg301", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No activity.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] }, { "sequence_org": "R", "sequence_mut": "Q", "comment": "No activity.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] } ] }, { "uniprot_canonical_ac": "P32318-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Pro304", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "No activity.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] } ] }, { "uniprot_canonical_ac": "P32318-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Glu97", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "No activity.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] }, { "sequence_org": "E", "sequence_mut": "Q", "comment": "No activity.", "evidence": [ { "database": "UniProtKB", "id": "P32318", "url": "https://www.uniprot.org/uniprotkb/P32318" }, { "database": "PubMed", "id": "17309261", "url": "https://glygen.org/publication/PubMed/17309261" } ] } ] } ], "record_id": "P32318-1" }, { "uniprot_canonical_ac": "P32319-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1579, "chemical_mass": 177777.0, "gene_names": "PEP1;PEP1;VPS10;VPT1;YBL03.22;YBL0302", "protein_name": "Vacuolar protein sorting/targeting protein VPS10", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:576", "name": "proteinuria", "description": "A kidney disease that is characterized by the presence of excess proteins in the urine.", "url": "https://disease-ontology.org/term/DOID:576", "evidence": [ { "id": "576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:576" } ], "weight": 0.0 }, { "disease_id": "DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta.", "url": "https://disease-ontology.org/term/DOID:7693", "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ], "weight": 0.0 } ], "biological_process": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "vesicle targeting, trans-Golgi to endosome", "id": "GO:0048203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048203", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "vacuolar sorting signal binding", "id": "GO:0010209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010209", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P32319", "url": "https://www.uniprot.org/uniprotkb/P32319" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32319-1", "start_pos": "1010", "end_pos": "1010", "site_lbl": "Asn1010", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1010, "start_aa": "Asn", "end_pos": 1010, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1010", "evidence": [ { "id": "P32319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32319#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "1303", "end_pos": "1303", "site_lbl": "Asn1303", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1303, "start_aa": "Asn", "end_pos": 1303, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1303", "evidence": [ { "id": "P32319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32319#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Asn170", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 170, "start_aa": "Asn", "end_pos": 170, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn170", "evidence": [ { "id": "P32319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32319#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "447", "end_pos": "447", "site_lbl": "Asn447", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 447, "start_aa": "Asn", "end_pos": 447, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn447", "evidence": [ { "id": "P32319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32319#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Thr463", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 463, "start_aa": "Thr", "end_pos": 463, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr463", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "793", "end_pos": "793", "site_lbl": "Asn793", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 793, "start_aa": "Asn", "end_pos": 793, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn793", "evidence": [ { "id": "P32319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32319#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Asn96", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 96, "start_aa": "Asn", "end_pos": 96, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn96", "evidence": [ { "id": "P32319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32319#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000113", "url": "https://www.yeastgenome.org/locus/S000000113" }, { "database": "iPTMnet", "id": "P32319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32319" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000113", "url": "https://www.yeastgenome.org/locus/S000000113" }, { "database": "iPTMnet", "id": "P32319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32319" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "1520", "end_pos": "1520", "site_lbl": "Ser1520", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000113", "url": "https://www.yeastgenome.org/locus/S000000113" }, { "database": "iPTMnet", "id": "P32319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32319" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "1537", "end_pos": "1537", "site_lbl": "Thr1537", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000113", "url": "https://www.yeastgenome.org/locus/S000000113" }, { "database": "iPTMnet", "id": "P32319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32319" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32319-1", "start_pos": "1543", "end_pos": "1543", "site_lbl": "Thr1543", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000113", "url": "https://www.yeastgenome.org/locus/S000000113" }, { "database": "iPTMnet", "id": "P32319", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32319" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32319-1" }, { "uniprot_canonical_ac": "P32323-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32323", "url": "https://www.uniprot.org/uniprotkb/P32323" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 725, "chemical_mass": 73354.0, "gene_names": "AGA1;AGA1;N3431", "protein_name": "A-agglutinin anchorage subunit", "disease": [], "molecular_function": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "P32323", "url": "https://www.uniprot.org/uniprotkb/P32323" } ], "pmid": "" } ], "cellular_component": [ { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32323", "url": "https://www.uniprot.org/uniprotkb/P32323" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P32323", "url": "https://www.uniprot.org/uniprotkb/P32323" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P32323", "url": "https://www.uniprot.org/uniprotkb/P32323" } ], "pmid": "" } ], "biological_process": [ { "name": "agglutination involved in conjugation with cellular fusion", "id": "GO:0000752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000752", "evidence": [ { "database": "UniProtKB", "id": "P32323", "url": "https://www.uniprot.org/uniprotkb/P32323" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32323-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Thr360", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 360, "start_aa": "Thr", "end_pos": 360, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr360", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] } ], "record_id": "P32323-1" }, { "uniprot_canonical_ac": "P32327-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32327", "url": "https://www.uniprot.org/uniprotkb/P32327" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1180, "chemical_mass": 130167.0, "gene_names": "PYC2;PYC2;YBR1507", "protein_name": "Pyruvate carboxylase 2", "disease": [ { "disease_id": "DOID:3649", "name": "pyruvate decarboxylase deficiency", "description": "A carbohydrate metabolic disorder characterized by the buildup of lactic acid in the body and a variety of neurological problems and caused by a deficiency of one of the three enzymes in the pyruvate dehydrogenase complex.", "url": "https://disease-ontology.org/term/DOID:3649", "evidence": [ { "id": "3649", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3649" } ], "weight": 0.0 }, { "disease_id": "DOID:3651", "name": "pyruvate carboxylase deficiency disease", "description": "A carbohydrate metabolic disorder that is characterized by deficiency of pyruvate carboxylase causing decreased utilization of carbohydrates and toxic accumulation of lactic acid, possibly has_symptom periodic lactate elevations, gastrointestinal upset, neonatal onset of metabolic acidosis, failure to thrive, developmental delay, seizures, death, and has_material_basis_in autosomal recessive inheritance of mutation in the PC gene, which encodes pyruvate carboxylase, a critical protein in the citric acid cycle and in gluconeogenesis.", "url": "https://disease-ontology.org/term/DOID:3651", "evidence": [ { "id": "3651", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3651" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32327", "url": "https://www.uniprot.org/uniprotkb/P32327" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32327", "url": "https://www.uniprot.org/uniprotkb/P32327" } ], "pmid": "" }, { "name": "pyruvate carboxylase activity", "id": "GO:0004736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004736", "evidence": [ { "database": "UniProtKB", "id": "P32327", "url": "https://www.uniprot.org/uniprotkb/P32327" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32327", "url": "https://www.uniprot.org/uniprotkb/P32327" } ], "pmid": "" } ], "biological_process": [ { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "P32327", "url": "https://www.uniprot.org/uniprotkb/P32327" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32327-1", "start_pos": "588", "end_pos": "588", "site_lbl": "Thr588", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 588, "start_aa": "Thr", "end_pos": 588, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr588", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32327-1", "start_pos": "1133", "end_pos": "1133", "site_lbl": "Ser1133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000422", "url": "https://www.yeastgenome.org/locus/S000000422" }, { "database": "iPTMnet", "id": "P32327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32327" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32327-1", "start_pos": "1177", "end_pos": "1177", "site_lbl": "Ser1177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000422", "url": "https://www.yeastgenome.org/locus/S000000422" }, { "database": "iPTMnet", "id": "P32327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32327" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32327-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000422", "url": "https://www.yeastgenome.org/locus/S000000422" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32327-1", "start_pos": "513", "end_pos": "513", "site_lbl": "Ser513", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000422", "url": "https://www.yeastgenome.org/locus/S000000422" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32327-1", "start_pos": "546", "end_pos": "546", "site_lbl": "Ser546", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000422", "url": "https://www.yeastgenome.org/locus/S000000422" }, { "database": "iPTMnet", "id": "P32327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32327-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Ser752", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000422", "url": "https://www.yeastgenome.org/locus/S000000422" }, { "database": "iPTMnet", "id": "P32327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32327" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32327-1", "start_pos": "901", "end_pos": "901", "site_lbl": "Thr901", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000422", "url": "https://www.yeastgenome.org/locus/S000000422" }, { "database": "iPTMnet", "id": "P32327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32327" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P32327-1" }, { "uniprot_canonical_ac": "P32328-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 564, "chemical_mass": 65880.0, "gene_names": "DBF20;DBF20", "protein_name": "Serine/threonine-protein kinase DBF20", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" }, { "name": "Sid2-Mob1 complex", "id": "GO:0034973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034973", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" }, { "name": "exit from mitosis", "id": "GO:0010458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010458", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" }, { "name": "regulation of exit from mitosis", "id": "GO:0007096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007096", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" }, { "name": "division septum assembly", "id": "GO:0000917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000917", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" }, { "name": "regulation of mRNA catabolic process", "id": "GO:0061013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061013", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32328-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ] } ] }, { "uniprot_canonical_ac": "P32328-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006315", "url": "https://www.yeastgenome.org/locus/S000006315" }, { "database": "iPTMnet", "id": "P32328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32328" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32328-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Ser325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006315", "url": "https://www.yeastgenome.org/locus/S000006315" }, { "database": "iPTMnet", "id": "P32328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32328" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32328-1", "start_pos": "366", "end_pos": "366", "site_lbl": "Ser366", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32328" }, { "database": "SGD", "id": "S000006315", "url": "https://www.yeastgenome.org/locus/S000006315" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32328-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Thr48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006315", "url": "https://www.yeastgenome.org/locus/S000006315" }, { "database": "iPTMnet", "id": "P32328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32328" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32328-1", "start_pos": "536", "end_pos": "536", "site_lbl": "Thr536", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32328", "url": "https://www.uniprot.org/uniprotkb/P32328" } ] } ] }, { "uniprot_canonical_ac": "P32328-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006315", "url": "https://www.yeastgenome.org/locus/S000006315" }, { "database": "iPTMnet", "id": "P32328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32328" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32328-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32328" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P32328-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32328" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006315", "url": "https://www.yeastgenome.org/locus/S000006315" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32328-1" }, { "uniprot_canonical_ac": "P32329-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 569, "chemical_mass": 60010.0, "gene_names": "YPS1;L2961;L9233.9;YAP3;YPS1", "protein_name": "Aspartic proteinase 3", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" } ], "pmid": "" }, { "name": "signal transduction involved in filamentous growth", "id": "GO:0001402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001402", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" } ], "pmid": "" }, { "name": "peptide pheromone maturation", "id": "GO:0007323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007323", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" } ], "pmid": "" } ], "molecular_function": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32329-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Thr162", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 162, "start_aa": "Thr", "end_pos": 162, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr162", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Asn203", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 203, "start_aa": "Asn", "end_pos": 203, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn203", "evidence": [ { "id": "P32329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32329#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Asn232", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 232, "start_aa": "Asn", "end_pos": 232, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn232", "evidence": [ { "id": "P32329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32329#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Asn242", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 242, "start_aa": "Asn", "end_pos": 242, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn242", "evidence": [ { "id": "P32329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32329#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Asn245", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 245, "start_aa": "Asn", "end_pos": 245, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn245", "evidence": [ { "id": "P32329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32329#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Asn299", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 299, "start_aa": "Asn", "end_pos": 299, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn299", "evidence": [ { "id": "P32329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32329#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Asn358", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 358, "start_aa": "Asn", "end_pos": 358, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn358", "evidence": [ { "id": "P32329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32329#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "480", "end_pos": "480", "site_lbl": "Asn480", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 480, "start_aa": "Asn", "end_pos": 480, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn480", "evidence": [ { "id": "P32329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32329#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Asn522", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 522, "start_aa": "Asn", "end_pos": 522, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn522", "evidence": [ { "id": "P32329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32329#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "532", "end_pos": "532", "site_lbl": "Asn532", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 532, "start_aa": "Asn", "end_pos": 532, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn532", "evidence": [ { "id": "P32329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32329#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Asn95", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 95, "start_aa": "Asn", "end_pos": 95, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn95", "evidence": [ { "id": "P32329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32329#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32329-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Asp101", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" }, { "database": "PubMed", "id": "9417119", "url": "https://glygen.org/publication/PubMed/9417119" } ] }, { "sequence_org": "D", "sequence_mut": "E", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P32329", "url": "https://www.uniprot.org/uniprotkb/P32329" }, { "database": "PubMed", "id": "9417119", "url": "https://glygen.org/publication/PubMed/9417119" } ] } ] } ], "record_id": "P32329-1" }, { "uniprot_canonical_ac": "P32332-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 324, "chemical_mass": 35153.0, "gene_names": "OAC1;OAC1;PMT1;PMT;YKL522", "protein_name": "Mitochondrial oxaloacetate transport protein", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "pmid": "" }, { "name": "sulfate transmembrane transporter activity", "id": "GO:0015116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015116", "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "pmid": "" }, { "name": "oxaloacetate transmembrane transporter activity", "id": "GO:0015131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015131", "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "pmid": "" }, { "name": "isopropylmalate transmembrane transporter activity", "id": "GO:0034658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034658", "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "pmid": "" }, { "name": "malonate(1-) transmembrane transporter activity", "id": "GO:1901239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901239", "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "pmid": "" } ], "biological_process": [ { "name": "sulfate transmembrane transport", "id": "GO:1902358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902358", "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "pmid": "" }, { "name": "oxaloacetate transport", "id": "GO:0015729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015729", "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "pmid": "" }, { "name": "isopropylmalate transport", "id": "GO:0034659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034659", "evidence": [ { "database": "UniProtKB", "id": "P32332", "url": "https://www.uniprot.org/uniprotkb/P32332" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32332-1" }, { "uniprot_canonical_ac": "P32334-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1306, "chemical_mass": 133115.0, "gene_names": "MSB2;MSB2", "protein_name": "Signaling mucin MSB2", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" }, { "name": "site of polarized growth", "id": "GO:0030427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030427", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" } ], "biological_process": [ { "name": "response to osmotic stress", "id": "GO:0006970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006970", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" }, { "name": "hyperosmotic response", "id": "GO:0006972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006972", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" }, { "name": "cellular bud site selection", "id": "GO:0000282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000282", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" }, { "name": "signal transduction involved in filamentous growth", "id": "GO:0001402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001402", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" }, { "name": "osmosensory signaling pathway via Sho1 osmosensor", "id": "GO:0007232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007232", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" } ], "molecular_function": [ { "name": "osmosensor activity", "id": "GO:0005034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005034", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32334-1", "start_pos": "1049", "end_pos": "1049", "site_lbl": "Asn1049", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1049, "start_aa": "Asn", "end_pos": 1049, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1049", "evidence": [ { "id": "P32334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32334#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1088", "end_pos": "1088", "site_lbl": "Asn1088", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1088, "start_aa": "Asn", "end_pos": 1088, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1088", "evidence": [ { "id": "P32334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32334#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1175", "end_pos": "1175", "site_lbl": "Asn1175", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1175, "start_aa": "Asn", "end_pos": 1175, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1175", "evidence": [ { "id": "P32334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32334#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Asn30", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 30, "start_aa": "Asn", "end_pos": 30, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn30", "evidence": [ { "id": "P32334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32334#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "859", "end_pos": "859", "site_lbl": "Asn859", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 859, "start_aa": "Asn", "end_pos": 859, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn859", "evidence": [ { "id": "P32334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32334#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "885", "end_pos": "885", "site_lbl": "Asn885", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 885, "start_aa": "Asn", "end_pos": 885, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn885", "evidence": [ { "id": "P32334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32334#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "901", "end_pos": "901", "site_lbl": "Thr901", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 901, "start_aa": "Thr", "end_pos": 901, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr901", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "945", "end_pos": "945", "site_lbl": "Asn945", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 945, "start_aa": "Asn", "end_pos": 945, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn945", "evidence": [ { "id": "P32334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32334#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1233", "end_pos": "1233", "site_lbl": "Ser1233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1248", "end_pos": "1248", "site_lbl": "Ser1248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1252", "end_pos": "1252", "site_lbl": "Ser1252", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1254", "end_pos": "1254", "site_lbl": "Thr1254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1256", "end_pos": "1256", "site_lbl": "Ser1256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1277", "end_pos": "1277", "site_lbl": "Ser1277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1278", "end_pos": "1278", "site_lbl": "Thr1278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1280", "end_pos": "1280", "site_lbl": "Thr1280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1284", "end_pos": "1284", "site_lbl": "Thr1284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1286", "end_pos": "1286", "site_lbl": "Ser1286", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1287", "end_pos": "1287", "site_lbl": "Ser1287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1297", "end_pos": "1297", "site_lbl": "Ser1297", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32334-1", "start_pos": "1300", "end_pos": "1300", "site_lbl": "Ser1300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32334", "url": "https://www.uniprot.org/uniprotkb/P32334" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32334" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003246", "url": "https://www.yeastgenome.org/locus/S000003246" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32334-1" }, { "uniprot_canonical_ac": "P32335-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 436, "chemical_mass": 50880.0, "gene_names": "MSS51;L8167.17;MSS51", "protein_name": "Protein MSS51, mitochondrial", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial translation", "id": "GO:0070131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070131", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial translation", "id": "GO:0070130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070130", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation regulator activity", "id": "GO:0045182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045182", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32335-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 56, "start_aa": "Thr", "end_pos": 56, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr56", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32335-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004193", "url": "https://www.yeastgenome.org/locus/S000004193" }, { "database": "iPTMnet", "id": "P32335", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32335" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32335-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Thr167", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "R", "comment": "Partially suppresses the respiratory defect of SHY1 mutants by increasing COX1 translation.", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" }, { "database": "PubMed", "id": "11782424", "url": "https://glygen.org/publication/PubMed/11782424" } ] } ] }, { "uniprot_canonical_ac": "P32335-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Phe199", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "I", "comment": "Partially suppresses the respiratory defect of SHY1 mutants by increasing COX1 translation.", "evidence": [ { "database": "UniProtKB", "id": "P32335", "url": "https://www.uniprot.org/uniprotkb/P32335" }, { "database": "PubMed", "id": "11782424", "url": "https://glygen.org/publication/PubMed/11782424" } ] } ] } ], "record_id": "P32335-1" }, { "uniprot_canonical_ac": "P32336-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 851, "chemical_mass": 94104.0, "gene_names": "NUD1;CDC18;NUD1", "protein_name": "Protein NUD1", "disease": [], "biological_process": [ { "name": "establishment of spindle localization", "id": "GO:0051293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051293", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" }, { "name": "regulation of mitotic cytokinesis", "id": "GO:1902412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902412", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" }, { "name": "positive regulation of exit from mitosis", "id": "GO:0031536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031536", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" }, { "name": "meiotic chromosome segregation", "id": "GO:0045132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045132", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" }, { "name": "astral microtubule organization", "id": "GO:0030953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030953", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" }, { "name": "initial mitotic spindle pole body separation", "id": "GO:0000073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000073", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" }, { "name": "septation initiation signaling", "id": "GO:0031028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031028", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" }, { "name": "outer plaque of mitotic spindle pole body", "id": "GO:0061499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061499", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" } ], "molecular_function": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32336-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Ser140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Thr145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Thr147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32851976", "url": "https://glygen.org/publication/PubMed/32851976" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Ser222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Ser240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Ser294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "32851976", "url": "https://glygen.org/publication/PubMed/32851976" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Thr362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Ser363", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Ser385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Thr388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32851976", "url": "https://glygen.org/publication/PubMed/32851976" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Thr392", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32851976", "url": "https://glygen.org/publication/PubMed/32851976" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Thr400", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Ser417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Ser419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32336", "url": "https://www.uniprot.org/uniprotkb/P32336" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "421", "end_pos": "421", "site_lbl": "Ser421", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "449", "end_pos": "449", "site_lbl": "Thr449", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Ser450", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Ser460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Ser469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32851976", "url": "https://glygen.org/publication/PubMed/32851976" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "806", "end_pos": "806", "site_lbl": "Thr806", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "32851976", "url": "https://glygen.org/publication/PubMed/32851976" } ] } ] }, { "uniprot_canonical_ac": "P32336-1", "start_pos": "843", "end_pos": "843", "site_lbl": "Thr843", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005900", "url": "https://www.yeastgenome.org/locus/S000005900" }, { "database": "iPTMnet", "id": "P32336", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32336" }, { "database": "PubMed", "id": "32851976", "url": "https://glygen.org/publication/PubMed/32851976" } ] } ] } ], "record_id": "P32336-1" }, { "uniprot_canonical_ac": "P32338-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 300, "chemical_mass": 33904.0, "gene_names": "RME1;CSP1;RME1", "protein_name": "Zinc finger protein RME1", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" }, { "name": "negative regulation of meiotic nuclear division", "id": "GO:0045835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045835", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" }, { "name": "positive regulation of invasive growth in response to glucose limitation", "id": "GO:2000219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000219", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32338-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003276", "url": "https://www.yeastgenome.org/locus/S000003276" }, { "database": "iPTMnet", "id": "P32338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32338-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Cys183", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Inactivates RME1.", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" }, { "database": "PubMed", "id": "1936989", "url": "https://glygen.org/publication/PubMed/1936989" } ] } ] }, { "uniprot_canonical_ac": "P32338-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Cys213", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Inactivates RME1.", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" }, { "database": "PubMed", "id": "1936989", "url": "https://glygen.org/publication/PubMed/1936989" } ] } ] }, { "uniprot_canonical_ac": "P32338-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Cys263", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Inactivates RME1.", "evidence": [ { "database": "UniProtKB", "id": "P32338", "url": "https://www.uniprot.org/uniprotkb/P32338" }, { "database": "PubMed", "id": "1936989", "url": "https://glygen.org/publication/PubMed/1936989" } ] } ] } ], "record_id": "P32338-1" }, { "uniprot_canonical_ac": "P32340-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32340", "url": "https://www.uniprot.org/uniprotkb/P32340" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 513, "chemical_mass": 57250.0, "gene_names": "NDI1;NDI1;YM7056.06C", "protein_name": "Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial", "disease": [ { "disease_id": "DOID:705", "name": "Leber hereditary optic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:705", "evidence": [ { "id": "705", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:705" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32340", "url": "https://www.uniprot.org/uniprotkb/P32340" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P32340", "url": "https://www.uniprot.org/uniprotkb/P32340" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P32340", "url": "https://www.uniprot.org/uniprotkb/P32340" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P32340", "url": "https://www.uniprot.org/uniprotkb/P32340" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "P32340", "url": "https://www.uniprot.org/uniprotkb/P32340" } ], "pmid": "" }, { "name": "NADH dehydrogenase (ubiquinone) (non-electrogenic) activity", "id": "GO:0120555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120555", "evidence": [ { "database": "UniProtKB", "id": "P32340", "url": "https://www.uniprot.org/uniprotkb/P32340" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "P32340", "url": "https://www.uniprot.org/uniprotkb/P32340" } ], "pmid": "" }, { "name": "mitochondrial electron transport, NADH to ubiquinone", "id": "GO:0006120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006120", "evidence": [ { "database": "UniProtKB", "id": "P32340", "url": "https://www.uniprot.org/uniprotkb/P32340" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32340-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32340-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32340" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" } ] } ] }, { "uniprot_canonical_ac": "P32340-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32340", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32340" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "SGD", "id": "S000004589", "url": "https://www.yeastgenome.org/locus/S000004589" } ] } ] } ], "record_id": "P32340-1" }, { "uniprot_canonical_ac": "P32342-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32342", "url": "https://www.uniprot.org/uniprotkb/P32342" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 167, "chemical_mass": 18425.0, "gene_names": "SRP21;SRP21;YKL527", "protein_name": "Signal recognition particle subunit SRP21", "disease": [], "cellular_component": [ { "name": "signal recognition particle, endoplasmic reticulum targeting", "id": "GO:0005786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005786", "evidence": [ { "database": "UniProtKB", "id": "P32342", "url": "https://www.uniprot.org/uniprotkb/P32342" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32342", "url": "https://www.uniprot.org/uniprotkb/P32342" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P32342", "url": "https://www.uniprot.org/uniprotkb/P32342" } ], "pmid": "" } ], "biological_process": [ { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "P32342", "url": "https://www.uniprot.org/uniprotkb/P32342" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition", "id": "GO:0006617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006617", "evidence": [ { "database": "UniProtKB", "id": "P32342", "url": "https://www.uniprot.org/uniprotkb/P32342" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32342-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Thr79", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32342-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Thr121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001605", "url": "https://www.yeastgenome.org/locus/S000001605" }, { "database": "iPTMnet", "id": "P32342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32342" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32342-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001605", "url": "https://www.yeastgenome.org/locus/S000001605" }, { "database": "iPTMnet", "id": "P32342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32342" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32342-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Thr24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001605", "url": "https://www.yeastgenome.org/locus/S000001605" }, { "database": "iPTMnet", "id": "P32342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32342" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32342-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32342" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000001605", "url": "https://www.yeastgenome.org/locus/S000001605" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32342-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001605", "url": "https://www.yeastgenome.org/locus/S000001605" }, { "database": "iPTMnet", "id": "P32342", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32342" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32342-1" }, { "uniprot_canonical_ac": "P32345-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 308, "chemical_mass": 35264.0, "gene_names": "PPH3;D4421;PPH3", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "disease": [ { "disease_id": "DOID:0070311", "name": "oligoasthenoteratozoospermia", "description": "A form of male infertility that is characterized by a combination of low number or oligozoospermia, poor motility or asthenozoospermia, and abnormal shape or teratozoospermia of sperms. OAT is the most common cause of male subfertility.", "url": "https://disease-ontology.org/term/DOID:0070311", "evidence": [ { "id": "0070311", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070311" } ], "weight": 0.0 }, { "disease_id": "DOID:0070515", "name": "chromosome 16p11.2 deletion syndrome, 593-kb", "description": "A chromosomal deletion syndrome characterized by language delay and mild intellectual disability that has_material_basis_in partial deletion of a contiguous 593-kb region of chromosome 16p11.2 (chr16:29.5-30.1 Mb).", "url": "https://disease-ontology.org/term/DOID:0070515", "evidence": [ { "id": "0070515", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070515" } ], "weight": 0.0 } ], "biological_process": [ { "name": "meiotic recombination checkpoint signaling", "id": "GO:0051598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051598", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via nonhomologous end joining", "id": "GO:2001034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001034", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" }, { "name": "negative regulation of DNA damage checkpoint", "id": "GO:2000002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000002", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" }, { "name": "regulation of TORC1 signaling", "id": "GO:1903432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903432", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" }, { "name": "negative regulation of glucose mediated signaling pathway", "id": "GO:1902660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902660", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" }, { "name": "protein phosphatase 4 complex", "id": "GO:0030289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030289", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "P32345", "url": "https://www.uniprot.org/uniprotkb/P32345" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32345-1" }, { "uniprot_canonical_ac": "P32347-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32347", "url": "https://www.uniprot.org/uniprotkb/P32347" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 362, "chemical_mass": 41349.0, "gene_names": "HEM12;HEM12;HEM6;POP3;YD9609.03", "protein_name": "Uroporphyrinogen decarboxylase", "disease": [ { "disease_id": "DOID:13268", "name": "porphyria", "description": "An inherited metabolic disorder that involves certain enzymes in the heme bio-synthetic pathway resulting in the overproduction and accumulation of the porphyrins.", "url": "https://disease-ontology.org/term/DOID:13268", "evidence": [ { "id": "13268", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13268" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:3132", "name": "porphyria cutanea tarda", "description": "An acute porphyria characterized by painful, blistering skin lesions that develop on sun-exposed skin.", "url": "https://disease-ontology.org/term/DOID:3132", "evidence": [ { "id": "3132", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3132" } ], "weight": 0.0 }, { "disease_id": "DOID:5230", "name": "hepatoerythropoietic porphyria", "description": "", "url": "https://disease-ontology.org/term/DOID:5230", "evidence": [ { "id": "5230", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5230" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32347", "url": "https://www.uniprot.org/uniprotkb/P32347" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32347", "url": "https://www.uniprot.org/uniprotkb/P32347" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32347", "url": "https://www.uniprot.org/uniprotkb/P32347" } ], "pmid": "" } ], "biological_process": [ { "name": "heme biosynthetic process", "id": "GO:0006783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006783", "evidence": [ { "database": "UniProtKB", "id": "P32347", "url": "https://www.uniprot.org/uniprotkb/P32347" } ], "pmid": "" }, { "name": "protoporphyrinogen IX biosynthetic process", "id": "GO:0006782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006782", "evidence": [ { "database": "UniProtKB", "id": "P32347", "url": "https://www.uniprot.org/uniprotkb/P32347" } ], "pmid": "" } ], "molecular_function": [ { "name": "uroporphyrinogen decarboxylase activity", "id": "GO:0004853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004853", "evidence": [ { "database": "UniProtKB", "id": "P32347", "url": "https://www.uniprot.org/uniprotkb/P32347" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32347-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Gly300", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Inactivation.", "evidence": [ { "database": "UniProtKB", "id": "P32347", "url": "https://www.uniprot.org/uniprotkb/P32347" } ] } ] }, { "uniprot_canonical_ac": "P32347-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Gly33", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Inactivation.", "evidence": [ { "database": "UniProtKB", "id": "P32347", "url": "https://www.uniprot.org/uniprotkb/P32347" } ] } ] }, { "uniprot_canonical_ac": "P32347-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Lys8", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Causes a defect in cell growth on a glycerol medium.", "evidence": [ { "database": "UniProtKB", "id": "P32347", "url": "https://www.uniprot.org/uniprotkb/P32347" }, { "database": "PubMed", "id": "26317124", "url": "https://glygen.org/publication/PubMed/26317124" } ] } ] } ], "record_id": "P32347-1" }, { "uniprot_canonical_ac": "P32349-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 654, "chemical_mass": 74017.0, "gene_names": "RPC82;P9677.11;RPC3;RPC80;RPC82", "protein_name": "DNA-directed RNA polymerase III subunit RPC3", "disease": [], "biological_process": [ { "name": "tRNA transcription by RNA polymerase III", "id": "GO:0042797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042797", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" } ], "pmid": "" }, { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" } ], "pmid": "" }, { "name": "termination of RNA polymerase III transcription", "id": "GO:0006386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006386", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" } ], "pmid": "" }, { "name": "RNA polymerase III complex", "id": "GO:0005666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005666", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" } ], "pmid": "" } ], "molecular_function": [ { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32349-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "323", "end_pos": "323", "site_lbl": "Ser323", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Ser392", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Ser394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32349", "url": "https://www.uniprot.org/uniprotkb/P32349" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Ser402", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "421", "end_pos": "421", "site_lbl": "Ser421", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32349-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Thr430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32349", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32349" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006394", "url": "https://www.yeastgenome.org/locus/S000006394" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32349-1" }, { "uniprot_canonical_ac": "P32350-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 737, "chemical_mass": 83843.0, "gene_names": "KNS1;KNS1", "protein_name": "Dual specificity protein kinase KNS1", "disease": [], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "pmid": "" }, { "name": "protein serine/threonine/tyrosine kinase activity", "id": "GO:0004712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004712", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase III", "id": "GO:0016480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016480", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32350-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Thr183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Ser247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Thr276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Ser280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Ser281", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Thr364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "562", "end_pos": "562", "site_lbl": "Thr562", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32350", "url": "https://www.uniprot.org/uniprotkb/P32350" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "583", "end_pos": "583", "site_lbl": "Ser583", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "589", "end_pos": "589", "site_lbl": "Ser589", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32350-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003942", "url": "https://www.yeastgenome.org/locus/S000003942" }, { "database": "iPTMnet", "id": "P32350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32350" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32350-1" }, { "uniprot_canonical_ac": "P32353-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32353", "url": "https://www.uniprot.org/uniprotkb/P32353" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 365, "chemical_mass": 42730.0, "gene_names": "ERG3;ERG3;L2150;PSO6;SYR1", "protein_name": "Delta(7)-sterol 5(6)-desaturase ERG3", "disease": [], "biological_process": [ { "name": "ergosterol biosynthetic process", "id": "GO:0006696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006696", "evidence": [ { "database": "UniProtKB", "id": "P32353", "url": "https://www.uniprot.org/uniprotkb/P32353" } ], "pmid": "" }, { "name": "sterol biosynthetic process", "id": "GO:0016126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016126", "evidence": [ { "database": "UniProtKB", "id": "P32353", "url": "https://www.uniprot.org/uniprotkb/P32353" } ], "pmid": "" } ], "molecular_function": [ { "name": "C-5 sterol desaturase activity", "id": "GO:0000248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000248", "evidence": [ { "database": "UniProtKB", "id": "P32353", "url": "https://www.uniprot.org/uniprotkb/P32353" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "P32353", "url": "https://www.uniprot.org/uniprotkb/P32353" } ], "pmid": "" }, { "name": "delta7-sterol 5(6)-desaturase activity", "id": "GO:0050046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050046", "evidence": [ { "database": "UniProtKB", "id": "P32353", "url": "https://www.uniprot.org/uniprotkb/P32353" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32353", "url": "https://www.uniprot.org/uniprotkb/P32353" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "P32353", "url": "https://www.uniprot.org/uniprotkb/P32353" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P32353", "url": "https://www.uniprot.org/uniprotkb/P32353" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32353", "url": "https://www.uniprot.org/uniprotkb/P32353" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32353-1" }, { "uniprot_canonical_ac": "P32356-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 751, "chemical_mass": 85879.0, "gene_names": "NTH1;NTH1;NTH;YD8119.07C", "protein_name": "Cytosolic neutral trehalase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" } ], "pmid": "" }, { "name": "alpha,alpha-trehalase activity", "id": "GO:0004555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004555", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" } ], "pmid": "" }, { "name": "trehalase activity", "id": "GO:0015927", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015927", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" } ], "pmid": "" } ], "biological_process": [ { "name": "trehalose catabolic process", "id": "GO:0005993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005993", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" } ], "pmid": "" }, { "name": "cellular response to desiccation", "id": "GO:0071465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071465", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32356-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Ser83", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 83, "start_aa": "Ser", "end_pos": 83, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser83", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32356", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32356" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20639203", "url": "https://glygen.org/publication/PubMed/20639203" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "33441790", "url": "https://glygen.org/publication/PubMed/33441790" }, { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27203178", "url": "https://glygen.org/publication/PubMed/27203178" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32102971", "url": "https://glygen.org/publication/PubMed/32102971" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "22320399", "url": "https://glygen.org/publication/PubMed/22320399" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes activity; when associated with A-20; A-21; A-58; A-60; A-135; A-149; A-260 and A-475. Abolishes activation by BMH1 and BMH2; when associated with A-20; A-21 and A-60.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "22320399", "url": "https://glygen.org/publication/PubMed/22320399" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Ser89", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 89, "start_aa": "Ser", "end_pos": 89, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser89", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32356", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32356" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 90, "start_aa": "Ser", "end_pos": 90, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser90", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32356", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32356" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 91, "start_aa": "Ser", "end_pos": 91, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser91", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32356", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32356" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20639203", "url": "https://glygen.org/publication/PubMed/20639203" }, { "database": "PubMed", "id": "33441790", "url": "https://glygen.org/publication/PubMed/33441790" }, { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27203178", "url": "https://glygen.org/publication/PubMed/27203178" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "22320399", "url": "https://glygen.org/publication/PubMed/22320399" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes activity; when associated with A-21; A-58; A-60; A-83; A-135; A-149; A-260 and A-475. Abolishes activation by BMH1 and BMH2; when associated with A-21; A-60 and A-83.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "22320399", "url": "https://glygen.org/publication/PubMed/22320399" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Thr217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "IntAct", "id": "P32356", "url": "https://www.ebi.ac.uk/intact/interactors/id:P32356*" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "17916074", "url": "https://glygen.org/publication/PubMed/17916074" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "33441790", "url": "https://glygen.org/publication/PubMed/33441790" }, { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27203178", "url": "https://glygen.org/publication/PubMed/27203178" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "22320399", "url": "https://glygen.org/publication/PubMed/22320399" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes activity; when associated with A-20; A-58; A-60; A-83; A-135; A-149; A-260 and A-475. Abolishes activation by BMH1 and BMH2; when associated with A-20; A-60 and A-83.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "22320399", "url": "https://glygen.org/publication/PubMed/22320399" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "IntAct", "id": "P32356", "url": "https://www.ebi.ac.uk/intact/interactors/id:P32356*" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "17916074", "url": "https://glygen.org/publication/PubMed/17916074" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Tyr254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Thr260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes activity; when associated with A-20; A-21; A-58; A-60; A-83; A-135; A-149 and A-475.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Tyr263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Tyr36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Ser402", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes activity; when associated with A-20; A-21; A-60; A-83; A-135; A-149; A-260 and A-475.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "33441790", "url": "https://glygen.org/publication/PubMed/33441790" }, { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27203178", "url": "https://glygen.org/publication/PubMed/27203178" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "22320399", "url": "https://glygen.org/publication/PubMed/22320399" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes activity; when associated with A-20; A-21; A-58; A-83; A-135; A-149; A-260 and A-475. Abolishes activation by BMH1 and BMH2; when associated with A-20; A-21 and A-83.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "22320399", "url": "https://glygen.org/publication/PubMed/22320399" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "618", "end_pos": "618", "site_lbl": "Ser618", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "33441790", "url": "https://glygen.org/publication/PubMed/33441790" }, { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27203178", "url": "https://glygen.org/publication/PubMed/27203178" }, { "database": "PubMed", "id": "27203179", "url": "https://glygen.org/publication/PubMed/27203179" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Thr79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Thr87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Tyr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002408", "url": "https://www.yeastgenome.org/locus/S000002408" }, { "database": "iPTMnet", "id": "P32356", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32356" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Gln120", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Decreases catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "29087344", "url": "https://glygen.org/publication/PubMed/29087344" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Thr135", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes activity; when associated with A-20; A-21; A-58; A-60; A-83; A-149; A-260 and A-475.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Thr149", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes activity; when associated with A-20; A-21; A-58; A-60; A-83; A-135; A-260 and A-475.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Ser475", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes activity; when associated with A-20; A-21; A-58; A-60; A-83; A-135; A-149 and A-260.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "10527941", "url": "https://glygen.org/publication/PubMed/10527941" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "478", "end_pos": "478", "site_lbl": "Asp478", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "29087344", "url": "https://glygen.org/publication/PubMed/29087344" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "674", "end_pos": "674", "site_lbl": "Glu674", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "29087344", "url": "https://glygen.org/publication/PubMed/29087344" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "686", "end_pos": "686", "site_lbl": "Arg686", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreases catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "29087344", "url": "https://glygen.org/publication/PubMed/29087344" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "690", "end_pos": "690", "site_lbl": "Glu690", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Severely decreases catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "29087344", "url": "https://glygen.org/publication/PubMed/29087344" } ] } ] }, { "uniprot_canonical_ac": "P32356-1", "start_pos": "691", "end_pos": "691", "site_lbl": "Tyr691", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P32356", "url": "https://www.uniprot.org/uniprotkb/P32356" }, { "database": "PubMed", "id": "29087344", "url": "https://glygen.org/publication/PubMed/29087344" } ] } ] } ], "record_id": "P32356-1" }, { "uniprot_canonical_ac": "P32363-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 452, "chemical_mass": 51242.0, "gene_names": "SPT14;CWH6;GPI3;P2269;SPT14", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit", "disease": [ { "disease_id": "DOID:0060284", "name": "paroxysmal nocturnal hemoglobinuria", "description": "An acquired hemolytic anemia that is characterized by abdominal pain, hematuria, esophageal dysmotility and thrombosis, has_material_basis_in defect in the cell membrane glycosyl phosphatidylinositols that protect red blood cells from the innate complement immune system.", "url": "https://disease-ontology.org/term/DOID:0060284", "evidence": [ { "id": "0060284", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060284" } ], "weight": 0.0 }, { "disease_id": "DOID:0060713", "name": "autosomal recessive congenital ichthyosis 4B", "description": "An autosomal recessive congenital ichthyosis characterized by severe neonatal ichthyosis with bilateral ectropion and eclabium, flattened and rudimentary nose and ears, constricting bands around the extremities and frequently lethality during infancy that has_material_basis_in homozygous or compound heterozygous mutation in the ABCA12 gene on chromosome 2q35.", "url": "https://disease-ontology.org/term/DOID:0060713", "evidence": [ { "id": "0060713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060713" } ], "weight": 0.0 }, { "disease_id": "DOID:0080139", "name": "multiple congenital anomalies-hypotonia-seizures syndrome 2", "description": "A multiple congenital anomalies-hypotonia-seizures syndrome that is characterized by X-linked recessive inheritance of dysmorphic features, neonatal hypotonia, myoclonic seizures and variable abnormalities involving the central nervous, cardiac, and urinary systems that has_material_basis_in mutation in the PIGA gene on chromosome Xp22.", "url": "https://disease-ontology.org/term/DOID:0080139", "evidence": [ { "id": "0080139", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080139" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex", "id": "GO:0000506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000506", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" } ], "pmid": "" } ], "biological_process": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol N-acetylglucosaminyltransferase activity", "id": "GO:0017176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017176", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32363-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32363" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32363-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006096", "url": "https://www.yeastgenome.org/locus/S000006096" }, { "database": "iPTMnet", "id": "P32363", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32363-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Glu289", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Severe growth defect.", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" }, { "database": "PubMed", "id": "14622279", "url": "https://glygen.org/publication/PubMed/14622279" } ] }, { "sequence_org": "E", "sequence_mut": "D", "comment": "Reduces the transferase reaction 12-fold.", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" }, { "database": "PubMed", "id": "14622279", "url": "https://glygen.org/publication/PubMed/14622279" } ] }, { "sequence_org": "E", "sequence_mut": "G", "comment": "Lethal.", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" }, { "database": "PubMed", "id": "14622279", "url": "https://glygen.org/publication/PubMed/14622279" } ] } ] }, { "uniprot_canonical_ac": "P32363-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Glu297", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Lethal.", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" }, { "database": "PubMed", "id": "14622279", "url": "https://glygen.org/publication/PubMed/14622279" } ] }, { "sequence_org": "E", "sequence_mut": "D", "comment": "No transferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" }, { "database": "PubMed", "id": "14622279", "url": "https://glygen.org/publication/PubMed/14622279" } ] }, { "sequence_org": "E", "sequence_mut": "G", "comment": "Lethal.", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" }, { "database": "PubMed", "id": "14622279", "url": "https://glygen.org/publication/PubMed/14622279" } ] } ] }, { "uniprot_canonical_ac": "P32363-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Cys301", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Reduces the transferase reaction 5-fold.", "evidence": [ { "database": "UniProtKB", "id": "P32363", "url": "https://www.uniprot.org/uniprotkb/P32363" }, { "database": "PubMed", "id": "14622279", "url": "https://glygen.org/publication/PubMed/14622279" } ] } ] } ], "record_id": "P32363-1" }, { "uniprot_canonical_ac": "P32364-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 656, "chemical_mass": 73799.0, "gene_names": "SMY1;SMY1;YKL409", "protein_name": "Kinesin-related protein SMY1", "disease": [ { "disease_id": "DOID:0061025", "name": "familial restrictive cardiomyopathy 6", "description": "A restrictive cardiomyopathy characterized by prenatal onset of severe restrictive cardiomyopathy predominantly involving the right ventricle, resulting in irreversible heart failure and early death that has_material_basis_in compound heterozygous mutation in the KIF20A gene on chromosome 5q31.", "url": "https://disease-ontology.org/term/DOID:0061025", "evidence": [ { "id": "0061025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061025" } ], "weight": 0.0 }, { "disease_id": "DOID:0110763", "name": "hereditary spastic paraplegia 10", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the KIF5A gene on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0110763", "evidence": [ { "id": "0110763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110763" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "cytoskeleton-dependent intracellular transport", "id": "GO:0030705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030705", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32364-1", "start_pos": "615", "end_pos": "615", "site_lbl": "Ser615", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 615, "start_aa": "Ser", "end_pos": 615, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser615", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32364", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32364" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "616", "end_pos": "616", "site_lbl": "Ser616", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 616, "start_aa": "Ser", "end_pos": 616, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser616", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32364", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32364" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "617", "end_pos": "617", "site_lbl": "Ser617", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 617, "start_aa": "Ser", "end_pos": 617, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser617", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32364", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32364" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "618", "end_pos": "618", "site_lbl": "Ser618", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 618, "start_aa": "Ser", "end_pos": 618, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser618", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32364", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32364" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "624", "end_pos": "624", "site_lbl": "Ser624", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 624, "start_aa": "Ser", "end_pos": 624, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser624", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32364", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32364" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "627", "end_pos": "627", "site_lbl": "Ser627", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 627, "start_aa": "Ser", "end_pos": 627, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser627", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32364", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32364" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Ser190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Ser408", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "411", "end_pos": "411", "site_lbl": "Ser411", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "548", "end_pos": "548", "site_lbl": "Ser548", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Ser553", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "557", "end_pos": "557", "site_lbl": "Ser557", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "562", "end_pos": "562", "site_lbl": "Ser562", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "566", "end_pos": "566", "site_lbl": "Ser566", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Ser570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Ser575", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "578", "end_pos": "578", "site_lbl": "Ser578", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "583", "end_pos": "583", "site_lbl": "Thr583", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32364", "url": "https://www.uniprot.org/uniprotkb/P32364" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "622", "end_pos": "622", "site_lbl": "Thr622", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "651", "end_pos": "651", "site_lbl": "Ser651", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "654", "end_pos": "654", "site_lbl": "Ser654", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32364-1", "start_pos": "656", "end_pos": "656", "site_lbl": "Ser656", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001562", "url": "https://www.yeastgenome.org/locus/S000001562" }, { "database": "iPTMnet", "id": "P32364", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32364" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P32364-1" }, { "uniprot_canonical_ac": "P32367-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 649, "chemical_mass": 73554.0, "gene_names": "TFC1;TFC1;YBR0919", "protein_name": "Transcription factor tau 95 kDa subunit", "disease": [], "cellular_component": [ { "name": "transcription factor TFIIIC complex", "id": "GO:0000127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000127", "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" } ], "pmid": "" } ], "biological_process": [ { "name": "5S class rRNA transcription by RNA polymerase III", "id": "GO:0042791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042791", "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" } ], "pmid": "" }, { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32367-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000327", "url": "https://www.yeastgenome.org/locus/S000000327" }, { "database": "iPTMnet", "id": "P32367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32367" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32367-1", "start_pos": "617", "end_pos": "617", "site_lbl": "Ser617", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000327", "url": "https://www.yeastgenome.org/locus/S000000327" }, { "database": "iPTMnet", "id": "P32367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32367-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000327", "url": "https://www.yeastgenome.org/locus/S000000327" }, { "database": "iPTMnet", "id": "P32367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32367-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000327", "url": "https://www.yeastgenome.org/locus/S000000327" }, { "database": "iPTMnet", "id": "P32367", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32367-1", "start_pos": "447", "end_pos": "447", "site_lbl": "Glu447", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Temperature-sensitive. TFCIII-DNA complexes present a shift in their 5' border, generate slow-migrating TFIIIB-DNA complexes upon stripping TFIIIC by heparin or heat treatment, and allow initiation at downstream sites. TFIIIC-DNA complexes highly unstable at high temperatures.", "evidence": [ { "database": "UniProtKB", "id": "P32367", "url": "https://www.uniprot.org/uniprotkb/P32367" }, { "database": "PubMed", "id": "12533520", "url": "https://glygen.org/publication/PubMed/12533520" } ] } ] } ], "record_id": "P32367-1" }, { "uniprot_canonical_ac": "P32377-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32377", "url": "https://www.uniprot.org/uniprotkb/P32377" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 396, "chemical_mass": 44116.0, "gene_names": "MVD1;ERG19;MPD;MVD1;N3427", "protein_name": "Diphosphomevalonate decarboxylase", "disease": [ { "disease_id": "DOID:3805", "name": "porokeratosis", "description": "", "url": "https://disease-ontology.org/term/DOID:3805", "evidence": [ { "id": "3805", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3805" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ergosterol biosynthetic process", "id": "GO:0006696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006696", "evidence": [ { "database": "UniProtKB", "id": "P32377", "url": "https://www.uniprot.org/uniprotkb/P32377" } ], "pmid": "" }, { "name": "sterol biosynthetic process", "id": "GO:0016126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016126", "evidence": [ { "database": "UniProtKB", "id": "P32377", "url": "https://www.uniprot.org/uniprotkb/P32377" } ], "pmid": "" }, { "name": "isopentenyl diphosphate biosynthetic process, mevalonate pathway", "id": "GO:0019287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019287", "evidence": [ { "database": "UniProtKB", "id": "P32377", "url": "https://www.uniprot.org/uniprotkb/P32377" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32377", "url": "https://www.uniprot.org/uniprotkb/P32377" } ], "pmid": "" }, { "name": "diphosphomevalonate decarboxylase activity", "id": "GO:0004163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004163", "evidence": [ { "database": "UniProtKB", "id": "P32377", "url": "https://www.uniprot.org/uniprotkb/P32377" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32377", "url": "https://www.uniprot.org/uniprotkb/P32377" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32377", "url": "https://www.uniprot.org/uniprotkb/P32377" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "P32377", "url": "https://www.uniprot.org/uniprotkb/P32377" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32377-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Ser143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005326", "url": "https://www.yeastgenome.org/locus/S000005326" }, { "database": "iPTMnet", "id": "P32377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32377-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005326", "url": "https://www.yeastgenome.org/locus/S000005326" }, { "database": "iPTMnet", "id": "P32377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32377-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005326", "url": "https://www.yeastgenome.org/locus/S000005326" } ] } ] }, { "uniprot_canonical_ac": "P32377-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Ser329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005326", "url": "https://www.yeastgenome.org/locus/S000005326" }, { "database": "iPTMnet", "id": "P32377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32377" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32377-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005326", "url": "https://www.yeastgenome.org/locus/S000005326" }, { "database": "iPTMnet", "id": "P32377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32377-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Ser385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005326", "url": "https://www.yeastgenome.org/locus/S000005326" }, { "database": "iPTMnet", "id": "P32377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32377-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005326", "url": "https://www.yeastgenome.org/locus/S000005326" }, { "database": "iPTMnet", "id": "P32377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32377-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005326", "url": "https://www.yeastgenome.org/locus/S000005326" }, { "database": "iPTMnet", "id": "P32377", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32377" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32377-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Leu79", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "Leads to thermosensitivity.", "evidence": [ { "database": "UniProtKB", "id": "P32377", "url": "https://www.uniprot.org/uniprotkb/P32377" }, { "database": "PubMed", "id": "9244250", "url": "https://glygen.org/publication/PubMed/9244250" } ] } ] } ], "record_id": "P32377-1" }, { "uniprot_canonical_ac": "P32378-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32378", "url": "https://www.uniprot.org/uniprotkb/P32378" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 372, "chemical_mass": 41001.0, "gene_names": "COQ2;COQ2;N3419", "protein_name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "disease": [ { "disease_id": "DOID:0050730", "name": "coenzyme Q10 deficiency disease", "description": "A mitochondrial metabolism disease that is characterized by a deficiency of CoQ10 resulting from reduced biosynthesis.", "url": "https://disease-ontology.org/term/DOID:0050730", "evidence": [ { "id": "0050730", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050730" } ], "weight": 0.0 }, { "disease_id": "DOID:0070238", "name": "primary coenzyme Q10 deficiency 1", "description": "A primary coenzyme Q10 deficiency that has_material_basis_in an autosomal recessive mutation of the COQ2 gene on chromosome 4q21.22-q21.23.", "url": "https://disease-ontology.org/term/DOID:0070238", "evidence": [ { "id": "0070238", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070238" } ], "weight": 0.0 }, { "disease_id": "DOID:10603", "name": "glucose intolerance", "description": "", "url": "https://disease-ontology.org/term/DOID:10603", "evidence": [ { "id": "10603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10603" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:4752", "name": "multiple system atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:4752", "evidence": [ { "id": "4752", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4752" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32378", "url": "https://www.uniprot.org/uniprotkb/P32378" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P32378", "url": "https://www.uniprot.org/uniprotkb/P32378" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P32378", "url": "https://www.uniprot.org/uniprotkb/P32378" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "P32378", "url": "https://www.uniprot.org/uniprotkb/P32378" } ], "pmid": "" } ], "biological_process": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "P32378", "url": "https://www.uniprot.org/uniprotkb/P32378" } ], "pmid": "" }, { "name": "isoprenoid biosynthetic process", "id": "GO:0008299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008299", "evidence": [ { "database": "UniProtKB", "id": "P32378", "url": "https://www.uniprot.org/uniprotkb/P32378" } ], "pmid": "" } ], "molecular_function": [ { "name": "4-hydroxybenzoate polyprenyltransferase activity", "id": "GO:0008412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008412", "evidence": [ { "database": "UniProtKB", "id": "P32378", "url": "https://www.uniprot.org/uniprotkb/P32378" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32378-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Thr140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32378" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005324", "url": "https://www.yeastgenome.org/locus/S000005324" } ] } ] }, { "uniprot_canonical_ac": "P32378-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005324", "url": "https://www.yeastgenome.org/locus/S000005324" }, { "database": "iPTMnet", "id": "P32378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32378" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32378-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005324", "url": "https://www.yeastgenome.org/locus/S000005324" }, { "database": "iPTMnet", "id": "P32378", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32378" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32378-1" }, { "uniprot_canonical_ac": "P32379-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32379", "url": "https://www.uniprot.org/uniprotkb/P32379" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 260, "chemical_mass": 28617.0, "gene_names": "PUP2;DOA5;G9155;PUP2", "protein_name": "Proteasome subunit alpha type-5", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "proteasome storage granule", "id": "GO:0034515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034515", "evidence": [ { "database": "UniProtKB", "id": "P32379", "url": "https://www.uniprot.org/uniprotkb/P32379" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32379", "url": "https://www.uniprot.org/uniprotkb/P32379" } ], "pmid": "" }, { "name": "proteasome core complex, alpha-subunit complex", "id": "GO:0019773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019773", "evidence": [ { "database": "UniProtKB", "id": "P32379", "url": "https://www.uniprot.org/uniprotkb/P32379" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P32379", "url": "https://www.uniprot.org/uniprotkb/P32379" } ], "pmid": "" }, { "name": "proteasomal ubiquitin-independent protein catabolic process", "id": "GO:0010499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010499", "evidence": [ { "database": "UniProtKB", "id": "P32379", "url": "https://www.uniprot.org/uniprotkb/P32379" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32379-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Ser128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Ser251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32379", "url": "https://www.uniprot.org/uniprotkb/P32379" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Ser260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Thr36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Thr42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Thr55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32379", "url": "https://www.uniprot.org/uniprotkb/P32379" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32379", "url": "https://www.uniprot.org/uniprotkb/P32379" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003485", "url": "https://www.yeastgenome.org/locus/S000003485" }, { "database": "iPTMnet", "id": "P32379", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32379" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32379-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Gly49", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In DOA5-1; slight decrease in activity.", "evidence": [ { "database": "UniProtKB", "id": "P32379", "url": "https://www.uniprot.org/uniprotkb/P32379" }, { "database": "PubMed", "id": "7781614", "url": "https://glygen.org/publication/PubMed/7781614" } ] } ] } ], "record_id": "P32379-1" }, { "uniprot_canonical_ac": "P32381-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 391, "chemical_mass": 44074.0, "gene_names": "ARP2;ACT2;ARP2;D2778", "protein_name": "Actin-related protein 2", "disease": [ { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" } ], "cellular_component": [ { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "Arp2/3 protein complex", "id": "GO:0005885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005885", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" } ], "biological_process": [ { "name": "Arp2/3 complex-mediated actin nucleation", "id": "GO:0034314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "actin nucleation", "id": "GO:0045010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045010", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "establishment of mitochondrion localization", "id": "GO:0051654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051654", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "mitochondrion inheritance", "id": "GO:0000001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000001", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "ascospore wall assembly", "id": "GO:0030476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030476", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" }, { "name": "actin cortical patch organization", "id": "GO:0044396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044396", "evidence": [ { "database": "UniProtKB", "id": "P32381", "url": "https://www.uniprot.org/uniprotkb/P32381" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32381-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002187", "url": "https://www.yeastgenome.org/locus/S000002187" }, { "database": "iPTMnet", "id": "P32381", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32381" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32381-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Thr49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002187", "url": "https://www.yeastgenome.org/locus/S000002187" }, { "database": "iPTMnet", "id": "P32381", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32381" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32381-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002187", "url": "https://www.yeastgenome.org/locus/S000002187" }, { "database": "iPTMnet", "id": "P32381", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32381" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32381-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002187", "url": "https://www.yeastgenome.org/locus/S000002187" }, { "database": "iPTMnet", "id": "P32381", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32381" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32381-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Tyr66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32381", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32381" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002187", "url": "https://www.yeastgenome.org/locus/S000002187" } ] } ] } ], "record_id": "P32381-1" }, { "uniprot_canonical_ac": "P32383-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32383", "url": "https://www.uniprot.org/uniprotkb/P32383" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 869, "chemical_mass": 100548.0, "gene_names": "PLC1;PLC1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1", "disease": [ { "disease_id": "DOID:0050424", "name": "familial adenomatous polyposis", "description": "An intestinal disease that is characterized by predisposition to colon cancer.", "url": "https://disease-ontology.org/term/DOID:0050424", "evidence": [ { "id": "0050424", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050424" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0070174", "name": "spermatogenic failure 17", "description": "A spermatogenic failure that is characterized by autosomal recessive inheritance of oocyte activation failure following intracytoplasmic sperm injection that has_material_basis_in mutation in the PLCZ1 gene on chromosome 12p12.", "url": "https://disease-ontology.org/term/DOID:0070174", "evidence": [ { "id": "0070174", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070174" } ], "weight": 0.0 }, { "disease_id": "DOID:0070615", "name": "autoinflammation, antibody deficiency, and immune dysregulation syndrome", "description": "An autoimmune disease characterized by recurrent blistering skin lesions with a dense inflammatory infiltrate and variable involvement of other tissues, including joints, the eye, and the gastrointestinal tract that has_material_basis in heterozygous mutation in the PLCG2 gene on chromosome 16q23.", "url": "https://disease-ontology.org/term/DOID:0070615", "evidence": [ { "id": "0070615", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070615" } ], "weight": 0.0 }, { "disease_id": "DOID:0080081", "name": "nonsyndromic congenital nail disorder 3", "description": "A nonsyndromic congenital nail disorder that is characterized by white discoloration of the nails.", "url": "https://disease-ontology.org/term/DOID:0080081", "evidence": [ { "id": "0080081", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080081" } ], "weight": 0.0 }, { "disease_id": "DOID:0080459", "name": "developmental and epileptic encephalopathy 12", "description": "A developmental and epileptic encephalopathy characterized by onset of refractory seizures in the first year of life with normal to mild developmental delay before onset of seizures but developmental regression and stagnation after seizure onset that has_material_basis_in homozygous or compound heterozygous mutation in the PLCB1 gene on chromosome 20p12.3.", "url": "https://disease-ontology.org/term/DOID:0080459", "evidence": [ { "id": "0080459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080459" } ], "weight": 0.0 }, { "disease_id": "DOID:0090064", "name": "familial cold autoinflammatory syndrome 3", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance of development of cutaneous urticaria, erythema and pruritus in response to cold exposure with. FCAS3 has_material_basis_in heterozygous deletion within the PLCG2 gene on chromosome 16q.", "url": "https://disease-ontology.org/term/DOID:0090064", "evidence": [ { "id": "0090064", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090064" } ], "weight": 0.0 }, { "disease_id": "DOID:0112303", "name": "spondylometaphyseal dysplasia with corneal dystrophy", "description": "A spondylometaphyseal dysplasia characterized by spondylometaphyseal dysplasia and corneal dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the PLCB3 gene on chromosome 11q13.1.", "url": "https://disease-ontology.org/term/DOID:0112303", "evidence": [ { "id": "0112303", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112303" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:2876", "name": "laryngeal squamous cell carcinoma", "description": "A laryngeal carcinoma that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:2876", "evidence": [ { "id": "2876", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2876" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4621", "name": "holoprosencephaly", "description": "A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies.", "url": "https://disease-ontology.org/term/DOID:4621", "evidence": [ { "id": "4621", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4621" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:5679", "name": "retinal disease", "description": "An eye disease that is located_in the retina.", "url": "https://disease-ontology.org/term/DOID:5679", "evidence": [ { "id": "5679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5679" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9408", "name": "acute myocardial infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:9408", "evidence": [ { "id": "9408", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9408" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate phospholipase C activity", "id": "GO:0004435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004435", "evidence": [ { "database": "UniProtKB", "id": "P32383", "url": "https://www.uniprot.org/uniprotkb/P32383" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P32383", "url": "https://www.uniprot.org/uniprotkb/P32383" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid catabolic process", "id": "GO:0009395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009395", "evidence": [ { "database": "UniProtKB", "id": "P32383", "url": "https://www.uniprot.org/uniprotkb/P32383" } ], "pmid": "" }, { "name": "phosphatidylinositol-mediated signaling", "id": "GO:0048015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015", "evidence": [ { "database": "UniProtKB", "id": "P32383", "url": "https://www.uniprot.org/uniprotkb/P32383" } ], "pmid": "" }, { "name": "protein localization to kinetochore", "id": "GO:0034501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034501", "evidence": [ { "database": "UniProtKB", "id": "P32383", "url": "https://www.uniprot.org/uniprotkb/P32383" } ], "pmid": "" }, { "name": "inositol phosphate biosynthetic process", "id": "GO:0032958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032958", "evidence": [ { "database": "UniProtKB", "id": "P32383", "url": "https://www.uniprot.org/uniprotkb/P32383" } ], "pmid": "" }, { "name": "signal transduction involved in filamentous growth", "id": "GO:0001402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001402", "evidence": [ { "database": "UniProtKB", "id": "P32383", "url": "https://www.uniprot.org/uniprotkb/P32383" } ], "pmid": "" } ], "cellular_component": [ { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "P32383", "url": "https://www.uniprot.org/uniprotkb/P32383" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P32383", "url": "https://www.uniprot.org/uniprotkb/P32383" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32383-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Ser223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006189", "url": "https://www.yeastgenome.org/locus/S000006189" }, { "database": "iPTMnet", "id": "P32383", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32383" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] } ] } ], "record_id": "P32383-1" }, { "uniprot_canonical_ac": "P32386-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1661, "chemical_mass": 189162.0, "gene_names": "YBT1;BAT1;YBT1", "protein_name": "ATP-dependent bile acid permease", "disease": [ { "disease_id": "DOID:0050650", "name": "familial atrial fibrillation", "description": "An atrial fibrillation that has_material_basis_in autosomal dominant inheritance of the familial atrial fibrillation (ATFB) genes.", "url": "https://disease-ontology.org/term/DOID:0050650", "evidence": [ { "id": "0050650", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050650" } ], "weight": 0.0 }, { "disease_id": "DOID:0060569", "name": "hypertrichotic osteochondrodysplasia Cantu type", "description": "An osteochondrodysplasia that is characterized by congenital hypertrichosis, neonatal macrosomia, and cardiomegaly.", "url": "https://disease-ontology.org/term/DOID:0060569", "evidence": [ { "id": "0060569", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060569" } ], "weight": 0.0 }, { "disease_id": "DOID:0070600", "name": "intellectual disability and myopathy syndrome", "description": "A syndrome characterized by global developmental delay with mildly impaired intellectual development, hypotonia, muscle weakness and fatigue, and abnormalities in brain white matter that has_material_basis in homozygous or compound heterozygous mutation in the ABCC9 gene on chromosome 12p12.", "url": "https://disease-ontology.org/term/DOID:0070600", "evidence": [ { "id": "0070600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070600" } ], "weight": 0.0 }, { "disease_id": "DOID:0110451", "name": "dilated cardiomyopathy 1O", "description": "A dilated cardiomyopathy that has_material_basis_in mutation in the ABCC9 gene on chromosome 12p12.1.", "url": "https://disease-ontology.org/term/DOID:0110451", "evidence": [ { "id": "0110451", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110451" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" }, { "name": "ATPase-coupled monocarboxylic acid transmembrane transporter activity", "id": "GO:0033285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033285", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" }, { "name": "monocarboxylic acid transport", "id": "GO:0015718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015718", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32386-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Asn6", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 6, "start_aa": "Asn", "end_pos": 6, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn6", "evidence": [ { "id": "P32386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32386#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "731", "end_pos": "731", "site_lbl": "Thr731", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 731, "start_aa": "Thr", "end_pos": 731, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr731", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Asn97", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 97, "start_aa": "Asn", "end_pos": 97, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn97", "evidence": [ { "id": "P32386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32386#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "1052", "end_pos": "1052", "site_lbl": "Ser1052", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "1510", "end_pos": "1510", "site_lbl": "Thr1510", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "1511", "end_pos": "1511", "site_lbl": "Ser1511", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "1515", "end_pos": "1515", "site_lbl": "Ser1515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "1516", "end_pos": "1516", "site_lbl": "Ser1516", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "1517", "end_pos": "1517", "site_lbl": "Thr1517", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "1519", "end_pos": "1519", "site_lbl": "Ser1519", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Ser81", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "936", "end_pos": "936", "site_lbl": "Ser936", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "937", "end_pos": "937", "site_lbl": "Ser937", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "940", "end_pos": "940", "site_lbl": "Ser940", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "944", "end_pos": "944", "site_lbl": "Ser944", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "945", "end_pos": "945", "site_lbl": "Ser945", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "952", "end_pos": "952", "site_lbl": "Ser952", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "953", "end_pos": "953", "site_lbl": "Ser953", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "954", "end_pos": "954", "site_lbl": "Thr954", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "955", "end_pos": "955", "site_lbl": "Ser955", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32386", "url": "https://www.uniprot.org/uniprotkb/P32386" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "957", "end_pos": "957", "site_lbl": "Ser957", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "968", "end_pos": "968", "site_lbl": "Ser968", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32386-1", "start_pos": "973", "end_pos": "973", "site_lbl": "Ser973", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003971", "url": "https://www.yeastgenome.org/locus/S000003971" }, { "database": "iPTMnet", "id": "P32386", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32386" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] } ], "record_id": "P32386-1" }, { "uniprot_canonical_ac": "P32389-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 672, "chemical_mass": 74373.0, "gene_names": "MET4;MET4;N2177", "protein_name": "Transcriptional activator of sulfur metabolism MET4", "disease": [], "biological_process": [ { "name": "response to arsenic-containing substance", "id": "GO:0046685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046685", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "response to cadmium ion", "id": "GO:0046686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046686", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "methionine biosynthetic process", "id": "GO:0009086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009086", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "sulfur amino acid metabolic process", "id": "GO:0000096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000096", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "cysteine biosynthetic process", "id": "GO:0019344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019344", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "regulation of sulfur metabolic process", "id": "GO:0042762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042762", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" }, { "name": "Cbf1-Met4-Met28 complex", "id": "GO:0089713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089713", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32389-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Thr299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Thr302", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Ser318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "326", "end_pos": "326", "site_lbl": "Ser326", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Ser328", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Ser334", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Ser416", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "528", "end_pos": "528", "site_lbl": "Ser528", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "547", "end_pos": "547", "site_lbl": "Ser547", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "549", "end_pos": "549", "site_lbl": "Ser549", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "563", "end_pos": "563", "site_lbl": "Tyr563", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32389-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Ser564", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32389", "url": "https://www.uniprot.org/uniprotkb/P32389" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32389", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32389" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005047", "url": "https://www.yeastgenome.org/locus/S000005047" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32389-1" }, { "uniprot_canonical_ac": "P32419-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 343, "chemical_mass": 37186.0, "gene_names": "MDH3;D2468;MDH3", "protein_name": "Malate dehydrogenase, peroxisomal", "disease": [ { "disease_id": "DOID:0080433", "name": "developmental and epileptic encephalopathy 51", "description": "A developmental and epileptic encephalopathy characterized by onset of intractable seizures and hypotonia in the first days or weeks of life and severely delayed psychomotor development that has_material_basis_in homozygous or compound heterozygous mutation in the MDH2 gene on chromosome 7q11.", "url": "https://disease-ontology.org/term/DOID:0080433", "evidence": [ { "id": "0080433", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080433" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" }, { "name": "L-malate dehydrogenase (NAD+) activity", "id": "GO:0030060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030060", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" }, { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" }, { "name": "malate metabolic process", "id": "GO:0006108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006108", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" }, { "name": "glyoxylate cycle", "id": "GO:0006097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006097", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" }, { "name": "NADH regeneration", "id": "GO:0006735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006735", "evidence": [ { "database": "UniProtKB", "id": "P32419", "url": "https://www.uniprot.org/uniprotkb/P32419" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32419-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32419" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P32419-1", "start_pos": "335", "end_pos": "335", "site_lbl": "Ser335", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002236", "url": "https://www.yeastgenome.org/locus/S000002236" }, { "database": "iPTMnet", "id": "P32419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32419" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32419-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Ser341", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002236", "url": "https://www.yeastgenome.org/locus/S000002236" }, { "database": "iPTMnet", "id": "P32419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32419" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32419-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32419" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] } ], "record_id": "P32419-1" }, { "uniprot_canonical_ac": "P32432-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32432", "url": "https://www.uniprot.org/uniprotkb/P32432" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 683, "chemical_mass": 74785.0, "gene_names": "SFP1;L8084.4;SFP1", "protein_name": "Transcription factor SFP1", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P32432", "url": "https://www.uniprot.org/uniprotkb/P32432" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32432", "url": "https://www.uniprot.org/uniprotkb/P32432" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P32432", "url": "https://www.uniprot.org/uniprotkb/P32432" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32432", "url": "https://www.uniprot.org/uniprotkb/P32432" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32432", "url": "https://www.uniprot.org/uniprotkb/P32432" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P32432", "url": "https://www.uniprot.org/uniprotkb/P32432" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32432", "url": "https://www.uniprot.org/uniprotkb/P32432" } ], "pmid": "" }, { "name": "regulation of cell size", "id": "GO:0008361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008361", "evidence": [ { "database": "UniProtKB", "id": "P32432", "url": "https://www.uniprot.org/uniprotkb/P32432" } ], "pmid": "" }, { "name": "positive regulation of ribosomal protein gene transcription by RNA polymerase II", "id": "GO:0060963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060963", "evidence": [ { "database": "UniProtKB", "id": "P32432", "url": "https://www.uniprot.org/uniprotkb/P32432" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32432-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 105, "start_aa": "Ser", "end_pos": 105, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser105", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 109, "start_aa": "Ser", "end_pos": 109, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser109", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 116, "start_aa": "Ser", "end_pos": 116, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser116", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 119, "start_aa": "Ser", "end_pos": 119, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser119", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 121, "start_aa": "Ser", "end_pos": 121, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser121", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 124, "start_aa": "Ser", "end_pos": 124, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser124", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Ser170", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 170, "start_aa": "Ser", "end_pos": 170, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser170", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "19328065", "url": "https://glygen.org/publication/PubMed/19328065" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004395", "url": "https://www.yeastgenome.org/locus/S000004395" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 172, "start_aa": "Ser", "end_pos": 172, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser172", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 181, "start_aa": "Ser", "end_pos": 181, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser181", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004395", "url": "https://www.yeastgenome.org/locus/S000004395" }, { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 183, "start_aa": "Ser", "end_pos": 183, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser183", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19328065", "url": "https://glygen.org/publication/PubMed/19328065" }, { "database": "SGD", "id": "S000004395", "url": "https://www.yeastgenome.org/locus/S000004395" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 256, "start_aa": "Ser", "end_pos": 256, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser256", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Ser257", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 257, "start_aa": "Ser", "end_pos": 257, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser257", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32432", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32432" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Thr341", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 341, "start_aa": "Thr", "end_pos": 341, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr341", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Tyr180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "19328065", "url": "https://glygen.org/publication/PubMed/19328065" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Ser209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004395", "url": "https://www.yeastgenome.org/locus/S000004395" }, { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Thr227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "19328065", "url": "https://glygen.org/publication/PubMed/19328065" }, { "database": "SGD", "id": "S000004395", "url": "https://www.yeastgenome.org/locus/S000004395" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Ser228", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19328065", "url": "https://glygen.org/publication/PubMed/19328065" }, { "database": "SGD", "id": "S000004395", "url": "https://www.yeastgenome.org/locus/S000004395" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "19328065", "url": "https://glygen.org/publication/PubMed/19328065" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Ser401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004395", "url": "https://www.yeastgenome.org/locus/S000004395" }, { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "446", "end_pos": "446", "site_lbl": "Thr446", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "19328065", "url": "https://glygen.org/publication/PubMed/19328065" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004395", "url": "https://www.yeastgenome.org/locus/S000004395" }, { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32432-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32432", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32432" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004395", "url": "https://www.yeastgenome.org/locus/S000004395" } ] } ] } ], "record_id": "P32432-1" }, { "uniprot_canonical_ac": "P32454-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32454", "url": "https://www.uniprot.org/uniprotkb/P32454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 952, "chemical_mass": 107755.0, "gene_names": "APE2;APE2;LAP1;YKL158W;YKL611;YKL612", "protein_name": "Aminopeptidase 2, mitochondrial", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P32454", "url": "https://www.uniprot.org/uniprotkb/P32454" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32454", "url": "https://www.uniprot.org/uniprotkb/P32454" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32454", "url": "https://www.uniprot.org/uniprotkb/P32454" } ], "pmid": "" }, { "name": "cell wall-bounded periplasmic space", "id": "GO:0030287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030287", "evidence": [ { "database": "UniProtKB", "id": "P32454", "url": "https://www.uniprot.org/uniprotkb/P32454" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P32454", "url": "https://www.uniprot.org/uniprotkb/P32454" } ], "pmid": "" }, { "name": "peptide catabolic process", "id": "GO:0043171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043171", "evidence": [ { "database": "UniProtKB", "id": "P32454", "url": "https://www.uniprot.org/uniprotkb/P32454" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32454", "url": "https://www.uniprot.org/uniprotkb/P32454" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "P32454", "url": "https://www.uniprot.org/uniprotkb/P32454" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32454-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Thr315", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 315, "start_aa": "Thr", "end_pos": 315, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr315", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Asn381", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 381, "start_aa": "Asn", "end_pos": 381, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn381", "evidence": [ { "id": "P32454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32454#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Asn713", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 713, "start_aa": "Asn", "end_pos": 713, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn713", "evidence": [ { "id": "P32454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32454#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Thr96", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32454", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32454" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Ser382", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Ser460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "530", "end_pos": "530", "site_lbl": "Ser530", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "536", "end_pos": "536", "site_lbl": "Ser536", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Ser569", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Ser596", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Ser604", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "606", "end_pos": "606", "site_lbl": "Thr606", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "645", "end_pos": "645", "site_lbl": "Ser645", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "735", "end_pos": "735", "site_lbl": "Ser735", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "737", "end_pos": "737", "site_lbl": "Ser737", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "809", "end_pos": "809", "site_lbl": "Ser809", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" }, { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32454-1", "start_pos": "898", "end_pos": "898", "site_lbl": "Ser898", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32454" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001640", "url": "https://www.yeastgenome.org/locus/S000001640" } ] } ] } ], "record_id": "P32454-1" }, { "uniprot_canonical_ac": "P32458-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 415, "chemical_mass": 47649.0, "gene_names": "CDC11;CDC11;J1833;PSL9", "protein_name": "Cell division control protein 11", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "biological_process": [ { "name": "septum digestion after cytokinesis", "id": "GO:0000920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000920", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "positive regulation of protein phosphorylation", "id": "GO:0001934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001934", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "septin ring assembly", "id": "GO:0000921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000921", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "actomyosin contractile ring assembly", "id": "GO:0000915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000915", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "division septum assembly", "id": "GO:0000917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000917", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "cellular bud neck septin ring organization", "id": "GO:0032186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032186", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "protein localization to bud neck", "id": "GO:0097271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097271", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "phosphatidylinositol-5-phosphate binding", "id": "GO:0010314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010314", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" } ], "cellular_component": [ { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "meiotic spindle", "id": "GO:0072687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072687", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "septin filament array", "id": "GO:0032160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032160", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "cellular bud neck septin ring", "id": "GO:0000144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000144", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "mating projection base", "id": "GO:0001400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001400", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "ascospore wall", "id": "GO:0005619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005619", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32458-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Ser297", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Ser300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Ser305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "311", "end_pos": "311", "site_lbl": "Thr311", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Ser316", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Ser317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Ser318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Ser320", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Thr321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "323", "end_pos": "323", "site_lbl": "Thr323", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Thr327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Ser351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Thr352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Thr358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003837", "url": "https://www.yeastgenome.org/locus/S000003837" }, { "database": "iPTMnet", "id": "P32458", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32458" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Gly230", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "Temperature-sensitive; no effect at 23 degrees Celsius but loss of function at 37 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" }, { "database": "PubMed", "id": "12665577", "url": "https://glygen.org/publication/PubMed/12665577" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Gly29", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Abolishes GTP-binding; no strong effect in vivo.", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" }, { "database": "PubMed", "id": "12665577", "url": "https://glygen.org/publication/PubMed/12665577" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Gly32", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Abolishes GTP-binding; no strong effect in vivo.", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" }, { "database": "PubMed", "id": "12665577", "url": "https://glygen.org/publication/PubMed/12665577" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Gly34", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Abolishes GTP-binding; no strong effect in vivo.", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" }, { "database": "PubMed", "id": "12665577", "url": "https://glygen.org/publication/PubMed/12665577" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Arg35", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Abolishes GTP-binding; no strong effect in vivo.", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" }, { "database": "PubMed", "id": "12665577", "url": "https://glygen.org/publication/PubMed/12665577" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Asn40", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "E", "comment": "Temperature-sensitive; no effect at 23 degrees Celsius but loss of function at 37 degrees Celsius; abolishes interaction with itself.", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" }, { "database": "PubMed", "id": "12665577", "url": "https://glygen.org/publication/PubMed/12665577" } ] } ] }, { "uniprot_canonical_ac": "P32458-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Lys412", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes sumoylation in vitro.", "evidence": [ { "database": "UniProtKB", "id": "P32458", "url": "https://www.uniprot.org/uniprotkb/P32458" }, { "database": "PubMed", "id": "10579719", "url": "https://glygen.org/publication/PubMed/10579719" } ] } ] } ], "record_id": "P32458-1" }, { "uniprot_canonical_ac": "P32462-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32462", "url": "https://www.uniprot.org/uniprotkb/P32462" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 438, "chemical_mass": 50615.0, "gene_names": "ERG24;ERG24;N0593", "protein_name": "Delta(14)-sterol reductase ERG24", "disease": [ { "disease_id": "DOID:0111588", "name": "Greenberg dysplasia", "description": "An inherited metabolic disorder characterized by a defect in cholesterol biosynthesis resulting in fetal hydrops, severe shortening of all long bones with a moth-eaten radiographic appearance, platyspondyly, disorganization of chondroosseous calcification, and ectopic ossification centers that has_material_basis_in homozygous or compound heterozygous mutation in LBR on chromosome 1q42.12.", "url": "https://disease-ontology.org/term/DOID:0111588", "evidence": [ { "id": "0111588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111588" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:1702", "name": "ichthyosis vulgaris", "description": "An ichthyosis that has_material_basis_in heterozygous mutation in the filaggrin gene (FLG) on chromosome 1q21 and is characterized by dead skin cells accumulate in thick, dry scales on your skin's surface.", "url": "https://disease-ontology.org/term/DOID:1702", "evidence": [ { "id": "1702", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1702" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 }, { "disease_id": "DOID:9631", "name": "Pelger-Huet anomaly", "description": "A hematopoietic system disease characterized by white blood cells with unusually shaped nuclei that has_material_basis_in heterozygous mutation in LBR on chromosome 1q42.12.", "url": "https://disease-ontology.org/term/DOID:9631", "evidence": [ { "id": "9631", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9631" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ergosterol biosynthetic process", "id": "GO:0006696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006696", "evidence": [ { "database": "UniProtKB", "id": "P32462", "url": "https://www.uniprot.org/uniprotkb/P32462" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32462", "url": "https://www.uniprot.org/uniprotkb/P32462" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32462", "url": "https://www.uniprot.org/uniprotkb/P32462" } ], "pmid": "" } ], "molecular_function": [ { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "P32462", "url": "https://www.uniprot.org/uniprotkb/P32462" } ], "pmid": "" }, { "name": "Delta14-sterol reductase activity", "id": "GO:0050613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050613", "evidence": [ { "database": "UniProtKB", "id": "P32462", "url": "https://www.uniprot.org/uniprotkb/P32462" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32462-1" }, { "uniprot_canonical_ac": "P32465-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 570, "chemical_mass": 63261.0, "gene_names": "HXT1;HOR4;HXT1", "protein_name": "Low-affinity glucose transporter HXT1", "disease": [], "biological_process": [ { "name": "D-glucose transmembrane transport", "id": "GO:1904659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904659", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" }, { "name": "carbohydrate transport", "id": "GO:0008643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008643", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" }, { "name": "mannose transmembrane transport", "id": "GO:0015761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015761", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" } ], "molecular_function": [ { "name": "fructose transmembrane transporter activity", "id": "GO:0005353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005353", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" }, { "name": "mannose transmembrane transporter activity", "id": "GO:0015578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015578", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" }, { "name": "carbohydrate:proton symporter activity", "id": "GO:0005351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005351", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" }, { "name": "D-glucose transmembrane transporter activity", "id": "GO:0055056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055056", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" }, { "name": "galactose transmembrane transporter activity", "id": "GO:0005354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005354", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" }, { "name": "pentose transmembrane transporter activity", "id": "GO:0015146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015146", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32465-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Asn228", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 228, "start_aa": "Asn", "end_pos": 228, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn228", "evidence": [ { "id": "P32465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32465#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Thr64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 64, "start_aa": "Thr", "end_pos": 64, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr64", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Tyr19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Thr316", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Thr31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32465", "url": "https://www.uniprot.org/uniprotkb/P32465" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "537", "end_pos": "537", "site_lbl": "Ser537", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P32465-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001136", "url": "https://www.yeastgenome.org/locus/S000001136" }, { "database": "iPTMnet", "id": "P32465", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P32465-1" }, { "uniprot_canonical_ac": "P32466-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 567, "chemical_mass": 62558.0, "gene_names": "HXT3;D9651.14;HXT3", "protein_name": "Low-affinity glucose transporter HXT3", "disease": [], "biological_process": [ { "name": "D-glucose transmembrane transport", "id": "GO:1904659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904659", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "pmid": "" }, { "name": "carbohydrate transport", "id": "GO:0008643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008643", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "pmid": "" }, { "name": "hexose transmembrane transport", "id": "GO:0008645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008645", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "pmid": "" } ], "molecular_function": [ { "name": "fructose transmembrane transporter activity", "id": "GO:0005353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005353", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "pmid": "" }, { "name": "mannose transmembrane transporter activity", "id": "GO:0015578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015578", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "pmid": "" }, { "name": "carbohydrate:proton symporter activity", "id": "GO:0005351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005351", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "pmid": "" }, { "name": "D-glucose transmembrane transporter activity", "id": "GO:0055056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055056", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32466-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Asn225", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 225, "start_aa": "Asn", "end_pos": 225, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn225", "evidence": [ { "id": "P32466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32466#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Asn416", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 416, "start_aa": "Asn", "end_pos": 416, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn416", "evidence": [ { "id": "P32466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32466#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Thr61", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32466", "url": "https://www.uniprot.org/uniprotkb/P32466" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Ser305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Thr50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "534", "end_pos": "534", "site_lbl": "Ser534", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32466-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32466", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32466" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000002753", "url": "https://www.yeastgenome.org/locus/S000002753" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P32466-1" }, { "uniprot_canonical_ac": "P32467-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32467", "url": "https://www.uniprot.org/uniprotkb/P32467" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 576, "chemical_mass": 63910.0, "gene_names": "HXT4;HXT4;LGT1;RAG1", "protein_name": "Low-affinity glucose transporter HXT4", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32467", "url": "https://www.uniprot.org/uniprotkb/P32467" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32467", "url": "https://www.uniprot.org/uniprotkb/P32467" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate transport", "id": "GO:0008643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008643", "evidence": [ { "database": "UniProtKB", "id": "P32467", "url": "https://www.uniprot.org/uniprotkb/P32467" } ], "pmid": "" }, { "name": "hexose transmembrane transport", "id": "GO:0008645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008645", "evidence": [ { "database": "UniProtKB", "id": "P32467", "url": "https://www.uniprot.org/uniprotkb/P32467" } ], "pmid": "" } ], "molecular_function": [ { "name": "fructose transmembrane transporter activity", "id": "GO:0005353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005353", "evidence": [ { "database": "UniProtKB", "id": "P32467", "url": "https://www.uniprot.org/uniprotkb/P32467" } ], "pmid": "" }, { "name": "mannose transmembrane transporter activity", "id": "GO:0015578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015578", "evidence": [ { "database": "UniProtKB", "id": "P32467", "url": "https://www.uniprot.org/uniprotkb/P32467" } ], "pmid": "" }, { "name": "carbohydrate:proton symporter activity", "id": "GO:0005351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005351", "evidence": [ { "database": "UniProtKB", "id": "P32467", "url": "https://www.uniprot.org/uniprotkb/P32467" } ], "pmid": "" }, { "name": "D-glucose transmembrane transporter activity", "id": "GO:0055056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055056", "evidence": [ { "database": "UniProtKB", "id": "P32467", "url": "https://www.uniprot.org/uniprotkb/P32467" } ], "pmid": "" }, { "name": "pentose transmembrane transporter activity", "id": "GO:0015146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015146", "evidence": [ { "database": "UniProtKB", "id": "P32467", "url": "https://www.uniprot.org/uniprotkb/P32467" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32467-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Thr34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32467-1", "start_pos": "425", "end_pos": "425", "site_lbl": "Asn425", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 425, "start_aa": "Asn", "end_pos": 425, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn425", "evidence": [ { "id": "P32467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32467#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32467-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001134", "url": "https://www.yeastgenome.org/locus/S000001134" }, { "database": "iPTMnet", "id": "P32467", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32467" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32467-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001134", "url": "https://www.yeastgenome.org/locus/S000001134" }, { "database": "iPTMnet", "id": "P32467", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32467" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32467-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Ser199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001134", "url": "https://www.yeastgenome.org/locus/S000001134" }, { "database": "iPTMnet", "id": "P32467", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32467" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32467-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001134", "url": "https://www.yeastgenome.org/locus/S000001134" }, { "database": "iPTMnet", "id": "P32467", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32467" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P32467-1" }, { "uniprot_canonical_ac": "P32468-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 407, "chemical_mass": 46668.0, "gene_names": "CDC12;CDC12;CLA10;PSL7", "protein_name": "Cell division control protein 12", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "biological_process": [ { "name": "septum digestion after cytokinesis", "id": "GO:0000920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000920", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "positive regulation of protein phosphorylation", "id": "GO:0001934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001934", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "septin ring assembly", "id": "GO:0000921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000921", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "maintenance of cell polarity", "id": "GO:0030011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030011", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "mitotic actomyosin contractile ring assembly", "id": "GO:1903475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903475", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "cellular bud neck septin ring organization", "id": "GO:0032186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032186", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "phosphatidylinositol-5-phosphate binding", "id": "GO:0010314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010314", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" } ], "cellular_component": [ { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "septin filament array", "id": "GO:0032160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032160", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "cellular bud neck septin ring", "id": "GO:0000144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000144", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "ascospore wall", "id": "GO:0005619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005619", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "cellular bud scar", "id": "GO:0005621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005621", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" }, { "name": "mating projection", "id": "GO:0005937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005937", "evidence": [ { "database": "UniProtKB", "id": "P32468", "url": "https://www.uniprot.org/uniprotkb/P32468" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32468-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Thr183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P32468-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Thr185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P32468-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Ser222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001149", "url": "https://www.yeastgenome.org/locus/S000001149" }, { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32468-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001149", "url": "https://www.yeastgenome.org/locus/S000001149" }, { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32468-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Ser228", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001149", "url": "https://www.yeastgenome.org/locus/S000001149" }, { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32468-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Ser248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001149", "url": "https://www.yeastgenome.org/locus/S000001149" }, { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32468-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001149", "url": "https://www.yeastgenome.org/locus/S000001149" }, { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32468-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Thr318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001149", "url": "https://www.yeastgenome.org/locus/S000001149" }, { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32468-1", "start_pos": "326", "end_pos": "326", "site_lbl": "Thr326", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001149", "url": "https://www.yeastgenome.org/locus/S000001149" }, { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32468-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Ser337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001149", "url": "https://www.yeastgenome.org/locus/S000001149" }, { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32468-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Thr354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001149", "url": "https://www.yeastgenome.org/locus/S000001149" }, { "database": "iPTMnet", "id": "P32468", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32468" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32468-1" }, { "uniprot_canonical_ac": "P32472-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32472", "url": "https://www.uniprot.org/uniprotkb/P32472" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 135, "chemical_mass": 14487.0, "gene_names": "FPR2;D9719.24;FKB2;FPR2", "protein_name": "Peptidyl-prolyl cis-trans isomerase FPR2", "disease": [ { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32472", "url": "https://www.uniprot.org/uniprotkb/P32472" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32472", "url": "https://www.uniprot.org/uniprotkb/P32472" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32472", "url": "https://www.uniprot.org/uniprotkb/P32472" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P32472", "url": "https://www.uniprot.org/uniprotkb/P32472" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32472", "url": "https://www.uniprot.org/uniprotkb/P32472" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P32472", "url": "https://www.uniprot.org/uniprotkb/P32472" } ], "pmid": "" } ], "molecular_function": [ { "name": "FK506 binding", "id": "GO:0005528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005528", "evidence": [ { "database": "UniProtKB", "id": "P32472", "url": "https://www.uniprot.org/uniprotkb/P32472" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "P32472", "url": "https://www.uniprot.org/uniprotkb/P32472" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32472-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002927", "url": "https://www.yeastgenome.org/locus/S000002927" }, { "database": "iPTMnet", "id": "P32472", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32472" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P32472-1" }, { "uniprot_canonical_ac": "P32473-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32473", "url": "https://www.uniprot.org/uniprotkb/P32473" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 366, "chemical_mass": 40054.0, "gene_names": "PDB1;PDB1;YBR1511", "protein_name": "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial", "disease": [ { "disease_id": "DOID:3649", "name": "pyruvate decarboxylase deficiency", "description": "A carbohydrate metabolic disorder characterized by the buildup of lactic acid in the body and a variety of neurological problems and caused by a deficiency of one of the three enzymes in the pyruvate dehydrogenase complex.", "url": "https://disease-ontology.org/term/DOID:3649", "evidence": [ { "id": "3649", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3649" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32473", "url": "https://www.uniprot.org/uniprotkb/P32473" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "P32473", "url": "https://www.uniprot.org/uniprotkb/P32473" } ], "pmid": "" }, { "name": "pyruvate dehydrogenase complex", "id": "GO:0045254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045254", "evidence": [ { "database": "UniProtKB", "id": "P32473", "url": "https://www.uniprot.org/uniprotkb/P32473" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32473", "url": "https://www.uniprot.org/uniprotkb/P32473" } ], "pmid": "" }, { "name": "pyruvate dehydrogenase (acetyl-transferring) activity", "id": "GO:0004739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004739", "evidence": [ { "database": "UniProtKB", "id": "P32473", "url": "https://www.uniprot.org/uniprotkb/P32473" } ], "pmid": "" } ], "biological_process": [ { "name": "pyruvate decarboxylation to acetyl-CoA", "id": "GO:0006086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006086", "evidence": [ { "database": "UniProtKB", "id": "P32473", "url": "https://www.uniprot.org/uniprotkb/P32473" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32473-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Ser140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000425", "url": "https://www.yeastgenome.org/locus/S000000425" }, { "database": "iPTMnet", "id": "P32473", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32473" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32473-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000425", "url": "https://www.yeastgenome.org/locus/S000000425" }, { "database": "iPTMnet", "id": "P32473", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32473" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32473-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Ser276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32473", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32473" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000425", "url": "https://www.yeastgenome.org/locus/S000000425" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32473-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Thr282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000425", "url": "https://www.yeastgenome.org/locus/S000000425" }, { "database": "iPTMnet", "id": "P32473", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32473" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32473-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Thr338", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000425", "url": "https://www.yeastgenome.org/locus/S000000425" }, { "database": "iPTMnet", "id": "P32473", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32473" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32473-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Tyr340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000425", "url": "https://www.yeastgenome.org/locus/S000000425" }, { "database": "iPTMnet", "id": "P32473", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32473" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32473-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Thr352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32473", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32473" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000425", "url": "https://www.yeastgenome.org/locus/S000000425" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32473-1" }, { "uniprot_canonical_ac": "P32474-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 517, "chemical_mass": 58982.0, "gene_names": "EUG1;D9719.23;EUG1", "protein_name": "Protein disulfide-isomerase EUG1", "disease": [ { "disease_id": "DOID:0060438", "name": "Cole-Carpenter syndrome", "description": "An osteogenesis imperfecta characterized by craniosynostosis, communicating hydrocephalus, ocular proptosis, marked postnatal growth failure, and distinctive facial appearance.", "url": "https://disease-ontology.org/term/DOID:0060438", "evidence": [ { "id": "0060438", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060438" } ], "weight": 0.0 }, { "disease_id": "DOID:11088", "name": "asphyxia neonatorum", "description": "A respiratory system disease that is characterized by deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm, usually to the brain.", "url": "https://disease-ontology.org/term/DOID:11088", "evidence": [ { "id": "11088", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11088" } ], "weight": 0.0 }, { "disease_id": "DOID:2048", "name": "autoimmune hepatitis", "description": "An autoimmune disease of gastrointestinal tract that results_in inflammation located_in liver caused by the body's immune system attacking the liver cells.", "url": "https://disease-ontology.org/term/DOID:2048", "evidence": [ { "id": "2048", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2048" } ], "weight": 0.0 }, { "disease_id": "DOID:2055", "name": "post-traumatic stress disorder", "description": "An anxiety disorder which results from a traumatic experience that results in psychological trauma.", "url": "https://disease-ontology.org/term/DOID:2055", "evidence": [ { "id": "2055", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2055" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:9778", "name": "irritable bowel syndrome", "description": "An intestinal disease that is characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause.", "url": "https://disease-ontology.org/term/DOID:9778", "evidence": [ { "id": "9778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9778" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein-disulfide reductase (glutathione) activity", "id": "GO:0019153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019153", "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" } ], "pmid": "" }, { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32474-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Asn159", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 159, "start_aa": "Asn", "end_pos": 159, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn159", "evidence": [ { "id": "P32474", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32474#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32474-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Asn174", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 174, "start_aa": "Asn", "end_pos": 174, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn174", "evidence": [ { "id": "P32474", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32474#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32474-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Asn207", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 207, "start_aa": "Asn", "end_pos": 207, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn207", "evidence": [ { "id": "P32474", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32474#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32474-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Asn293", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 293, "start_aa": "Asn", "end_pos": 293, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn293", "evidence": [ { "id": "P32474", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32474#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32474-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Thr30", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32474-1", "start_pos": "462", "end_pos": "462", "site_lbl": "Asn462", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 462, "start_aa": "Asn", "end_pos": 462, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn462", "evidence": [ { "id": "P32474", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32474#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32474-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Ser424", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32474", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32474" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P32474-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Ser408", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "C", "comment": "Increases PDI activity.", "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" }, { "database": "PubMed", "id": "11485577", "url": "https://glygen.org/publication/PubMed/11485577" } ] } ] }, { "uniprot_canonical_ac": "P32474-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "C", "comment": "Increases PDI activity.", "evidence": [ { "database": "UniProtKB", "id": "P32474", "url": "https://www.uniprot.org/uniprotkb/P32474" }, { "database": "PubMed", "id": "11485577", "url": "https://glygen.org/publication/PubMed/11485577" } ] } ] } ], "record_id": "P32474-1" }, { "uniprot_canonical_ac": "P32476-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32476", "url": "https://www.uniprot.org/uniprotkb/P32476" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 496, "chemical_mass": 55126.0, "gene_names": "ERG1;ERG1", "protein_name": "Squalene epoxidase ERG1", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ergosterol biosynthetic process", "id": "GO:0006696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006696", "evidence": [ { "database": "UniProtKB", "id": "P32476", "url": "https://www.uniprot.org/uniprotkb/P32476" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32476", "url": "https://www.uniprot.org/uniprotkb/P32476" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P32476", "url": "https://www.uniprot.org/uniprotkb/P32476" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32476", "url": "https://www.uniprot.org/uniprotkb/P32476" } ], "pmid": "" } ], "molecular_function": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "P32476", "url": "https://www.uniprot.org/uniprotkb/P32476" } ], "pmid": "" }, { "name": "squalene monooxygenase activity", "id": "GO:0004506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004506", "evidence": [ { "database": "UniProtKB", "id": "P32476", "url": "https://www.uniprot.org/uniprotkb/P32476" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32476-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Ser276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003407", "url": "https://www.yeastgenome.org/locus/S000003407" }, { "database": "iPTMnet", "id": "P32476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32476" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32476-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Ser368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003407", "url": "https://www.yeastgenome.org/locus/S000003407" }, { "database": "iPTMnet", "id": "P32476", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32476" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32476-1" }, { "uniprot_canonical_ac": "P32478-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32478", "url": "https://www.uniprot.org/uniprotkb/P32478" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 413, "chemical_mass": 41059.0, "gene_names": "HSP150;CCW7;HSP150;J0558;ORE1;PIR2", "protein_name": "Cell wall mannoprotein HSP150", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P32478", "url": "https://www.uniprot.org/uniprotkb/P32478" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32478", "url": "https://www.uniprot.org/uniprotkb/P32478" } ], "pmid": "" }, { "name": "cellular bud scar", "id": "GO:0005621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005621", "evidence": [ { "database": "UniProtKB", "id": "P32478", "url": "https://www.uniprot.org/uniprotkb/P32478" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P32478", "url": "https://www.uniprot.org/uniprotkb/P32478" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32478", "url": "https://www.uniprot.org/uniprotkb/P32478" } ], "pmid": "" }, { "name": "structural constituent of cell wall", "id": "GO:0005199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005199", "evidence": [ { "database": "UniProtKB", "id": "P32478", "url": "https://www.uniprot.org/uniprotkb/P32478" } ], "pmid": "" } ], "biological_process": [ { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P32478", "url": "https://www.uniprot.org/uniprotkb/P32478" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32478-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Thr318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32478" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32478-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003695", "url": "https://www.yeastgenome.org/locus/S000003695" }, { "database": "iPTMnet", "id": "P32478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32478" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32478-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32478" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003695", "url": "https://www.yeastgenome.org/locus/S000003695" } ] } ] } ], "record_id": "P32478-1" }, { "uniprot_canonical_ac": "P32479-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 840, "chemical_mass": 93858.0, "gene_names": "HIR1;HIR1;YBL0318", "protein_name": "Protein HIR1", "disease": [ { "disease_id": "DOID:0060413", "name": "chromosome 22q11.2 deletion syndrome, distal", "description": "A chromosomal deletion syndrome that has_material_basis_in deletion of the chromosome 22q11.2 region, distinct from DiGeorge syndrome and velocardiofacial syndrome.", "url": "https://disease-ontology.org/term/DOID:0060413", "evidence": [ { "id": "0060413", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060413" } ], "weight": 0.0 }, { "disease_id": "DOID:6419", "name": "tetralogy of Fallot", "description": "", "url": "https://disease-ontology.org/term/DOID:6419", "evidence": [ { "id": "6419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6419" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase III", "id": "GO:0016480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016480", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": "GO:1902275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902275", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" }, { "name": "HIR complex", "id": "GO:0000417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000417", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32479-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000104", "url": "https://www.yeastgenome.org/locus/S000000104" }, { "database": "iPTMnet", "id": "P32479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32479" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32479-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Tyr18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32479" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P32479-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Tyr21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32479" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P32479-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32479" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P32479-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Ser507", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000104", "url": "https://www.yeastgenome.org/locus/S000000104" }, { "database": "iPTMnet", "id": "P32479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32479" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32479-1", "start_pos": "579", "end_pos": "579", "site_lbl": "Ser579", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000104", "url": "https://www.yeastgenome.org/locus/S000000104" }, { "database": "iPTMnet", "id": "P32479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32479" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32479-1", "start_pos": "581", "end_pos": "581", "site_lbl": "Ser581", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000104", "url": "https://www.yeastgenome.org/locus/S000000104" }, { "database": "iPTMnet", "id": "P32479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32479" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32479-1", "start_pos": "602", "end_pos": "602", "site_lbl": "Ser602", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32479" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000104", "url": "https://www.yeastgenome.org/locus/S000000104" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32479-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Ser610", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32479", "url": "https://www.uniprot.org/uniprotkb/P32479" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32479", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32479" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000104", "url": "https://www.yeastgenome.org/locus/S000000104" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32479-1" }, { "uniprot_canonical_ac": "P32480-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 875, "chemical_mass": 98445.0, "gene_names": "HIR2;HIR2;OR26.31;SPT1", "protein_name": "Protein HIR2", "disease": [ { "disease_id": "DOID:0060413", "name": "chromosome 22q11.2 deletion syndrome, distal", "description": "A chromosomal deletion syndrome that has_material_basis_in deletion of the chromosome 22q11.2 region, distinct from DiGeorge syndrome and velocardiofacial syndrome.", "url": "https://disease-ontology.org/term/DOID:0060413", "evidence": [ { "id": "0060413", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060413" } ], "weight": 0.0 }, { "disease_id": "DOID:6419", "name": "tetralogy of Fallot", "description": "", "url": "https://disease-ontology.org/term/DOID:6419", "evidence": [ { "id": "6419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6419" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase III", "id": "GO:0016480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016480", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": "GO:1902275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902275", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" }, { "name": "transcription elongation-coupled chromatin remodeling", "id": "GO:0140673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140673", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" }, { "name": "HIR complex", "id": "GO:0000417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000417", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32480-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Thr460", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 460, "start_aa": "Thr", "end_pos": 460, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr460", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32480" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005564", "url": "https://www.yeastgenome.org/locus/S000005564" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32480-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Thr206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32480" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32480-1", "start_pos": "428", "end_pos": "428", "site_lbl": "Thr428", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32480" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P32480-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005564", "url": "https://www.yeastgenome.org/locus/S000005564" } ] } ] }, { "uniprot_canonical_ac": "P32480-1", "start_pos": "443", "end_pos": "443", "site_lbl": "Thr443", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005564", "url": "https://www.yeastgenome.org/locus/S000005564" }, { "database": "iPTMnet", "id": "P32480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32480" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32480-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Ser713", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32480", "url": "https://www.uniprot.org/uniprotkb/P32480" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32480", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32480" }, { "database": "SGD", "id": "S000005564", "url": "https://www.yeastgenome.org/locus/S000005564" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32480-1" }, { "uniprot_canonical_ac": "P32486-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 720, "chemical_mass": 80123.0, "gene_names": "KRE6;CWH48;KRE6", "protein_name": "Beta-glucan synthesis-associated protein KRE6", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "pmid": "" }, { "name": "site of polarized growth", "id": "GO:0030427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030427", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "pmid": "" } ], "molecular_function": [ { "name": "glucosidase activity", "id": "GO:0015926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015926", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "pmid": "" } ], "biological_process": [ { "name": "(1->6)-beta-D-glucan biosynthetic process", "id": "GO:0006078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006078", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32486-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Asn374", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 374, "start_aa": "Asn", "end_pos": 374, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn374", "evidence": [ { "id": "P32486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32486#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Asn461", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 461, "start_aa": "Asn", "end_pos": 461, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn461", "evidence": [ { "id": "P32486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32486#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Asn538", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 538, "start_aa": "Asn", "end_pos": 538, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn538", "evidence": [ { "id": "P32486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32486#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "563", "end_pos": "563", "site_lbl": "Asn563", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 563, "start_aa": "Asn", "end_pos": 563, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn563", "evidence": [ { "id": "P32486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32486#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "691", "end_pos": "691", "site_lbl": "Asn691", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 691, "start_aa": "Asn", "end_pos": 691, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn691", "evidence": [ { "id": "P32486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32486#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Thr117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Tyr155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Thr163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ser164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Thr166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Thr176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Ser62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Tyr76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Ser81", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32486", "url": "https://www.uniprot.org/uniprotkb/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Ser83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32486-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32486", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32486" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006363", "url": "https://www.yeastgenome.org/locus/S000006363" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32486-1" }, { "uniprot_canonical_ac": "P32491-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 506, "chemical_mass": 56758.0, "gene_names": "MKK2;LPI6C;LPI6;MKK2;SSP33", "protein_name": "MAP kinase kinase MKK2/SSP33", "disease": [ { "disease_id": "DOID:0080690", "name": "RASopathy", "description": "A syndrome that has_material_basis_in mutations in genes that alter the Ras subfamily and mitogen-activated protein kinases that control signal transduction.", "url": "https://disease-ontology.org/term/DOID:0080690", "evidence": [ { "id": "0080690", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080690" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "MAP kinase kinase activity", "id": "GO:0004708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004708", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "cell integrity MAPK cascade", "id": "GO:0000196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000196", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" }, { "name": "regulation of fungal-type cell wall organization", "id": "GO:0060237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060237", "evidence": [ { "database": "UniProtKB", "id": "P32491", "url": "https://www.uniprot.org/uniprotkb/P32491" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32491-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Ser132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006061", "url": "https://www.yeastgenome.org/locus/S000006061" }, { "database": "iPTMnet", "id": "P32491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32491" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32491-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006061", "url": "https://www.yeastgenome.org/locus/S000006061" }, { "database": "iPTMnet", "id": "P32491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32491" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32491-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Thr137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006061", "url": "https://www.yeastgenome.org/locus/S000006061" }, { "database": "iPTMnet", "id": "P32491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32491" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32491-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Thr153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006061", "url": "https://www.yeastgenome.org/locus/S000006061" }, { "database": "iPTMnet", "id": "P32491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32491" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32491-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Ser162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32491" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006061", "url": "https://www.yeastgenome.org/locus/S000006061" } ] } ] }, { "uniprot_canonical_ac": "P32491-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Thr215", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32491" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P32491-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Thr216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32491" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P32491-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32491", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32491" }, { "database": "PubMed", "id": "17711850", "url": "https://glygen.org/publication/PubMed/17711850" }, { "database": "SGD", "id": "S000006061", "url": "https://www.yeastgenome.org/locus/S000006061" } ] } ] } ], "record_id": "P32491-1" }, { "uniprot_canonical_ac": "P32492-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1471, "chemical_mass": 169344.0, "gene_names": "MYO4;FUN22;MYO4;SHE1", "protein_name": "Myosin-4", "disease": [ { "disease_id": "DOID:0060775", "name": "microvillus inclusion disease", "description": "A congenital diarrhea characterized by onset of intractable life-threatening watery diarrhea during infancy, lack of microvilli on the surface of enterocytes and occurrence of intracellular vacuolar structures containing microvilli that has_material_basis_in homozygous or compound heterozygous mutation in the MYO5B gene on chromosome 18q21.", "url": "https://disease-ontology.org/term/DOID:0060775", "evidence": [ { "id": "0060775", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060775" } ], "weight": 0.0 }, { "disease_id": "DOID:0060832", "name": "Griscelli syndrome type 1", "description": "A Griscelli syndrome characterized by silvery gray sheen of the hair, hypopigmentation of the skin and neurological impairment without immunodeficiency that has_material_basis_in mutations in the MYO5A gene on chromosome 15q21.2.", "url": "https://disease-ontology.org/term/DOID:0060832", "evidence": [ { "id": "0060832", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060832" } ], "weight": 0.0 }, { "disease_id": "DOID:0070221", "name": "progressive familial intrahepatic cholestasis", "description": "An intrahepatic cholestasis characterized by early onset of chronic unremitting cholestasis of hepatocellular origin that progresses to hepatic fibrosis, cirrhosis, and end-stage liver disease before adulthood.", "url": "https://disease-ontology.org/term/DOID:0070221", "evidence": [ { "id": "0070221", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070221" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:6713", "name": "cerebrovascular disease", "description": "An vascular disease that is characterized by dysfunction of the blood vessels supplying the brain.", "url": "https://disease-ontology.org/term/DOID:6713", "evidence": [ { "id": "6713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6713" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "vesicle transport along actin filament", "id": "GO:0030050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030050", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "mating type switching", "id": "GO:0007533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007533", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" }, { "name": "endoplasmic reticulum inheritance", "id": "GO:0048309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048309", "evidence": [ { "database": "UniProtKB", "id": "P32492", "url": "https://www.uniprot.org/uniprotkb/P32492" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32492-1", "start_pos": "1041", "end_pos": "1041", "site_lbl": "Ser1041", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000027", "url": "https://www.yeastgenome.org/locus/S000000027" }, { "database": "iPTMnet", "id": "P32492", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32492" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32492-1", "start_pos": "1044", "end_pos": "1044", "site_lbl": "Ser1044", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000027", "url": "https://www.yeastgenome.org/locus/S000000027" }, { "database": "iPTMnet", "id": "P32492", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32492" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32492-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Ser585", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000027", "url": "https://www.yeastgenome.org/locus/S000000027" }, { "database": "iPTMnet", "id": "P32492", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32492" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32492-1", "start_pos": "587", "end_pos": "587", "site_lbl": "Ser587", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000027", "url": "https://www.yeastgenome.org/locus/S000000027" }, { "database": "iPTMnet", "id": "P32492", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32492" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32492-1", "start_pos": "934", "end_pos": "934", "site_lbl": "Ser934", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000027", "url": "https://www.yeastgenome.org/locus/S000000027" }, { "database": "iPTMnet", "id": "P32492", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32492" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32492-1", "start_pos": "965", "end_pos": "965", "site_lbl": "Thr965", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32492", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32492" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000027", "url": "https://www.yeastgenome.org/locus/S000000027" } ] } ] } ], "record_id": "P32492-1" }, { "uniprot_canonical_ac": "P32495-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 156, "chemical_mass": 17122.0, "gene_names": "NHP2;D1045;NHP2", "protein_name": "H/ACA ribonucleoprotein complex subunit NHP2", "disease": [ { "disease_id": "DOID:0070017", "name": "autosomal recessive dyskeratosis congenita 2", "description": "A dyskeratosis congenita that has_material_basis_in an autosomal recessive mutation of the NOLA2 gene on chromosome 5q35.3.", "url": "https://disease-ontology.org/term/DOID:0070017", "evidence": [ { "id": "0070017", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070017" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" } ], "pmid": "" }, { "name": "box H/ACA snoRNP complex", "id": "GO:0031429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031429", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" } ], "pmid": "" }, { "name": "sno(s)RNA-containing ribonucleoprotein complex", "id": "GO:0005732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005732", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" } ], "pmid": "" }, { "name": "rRNA pseudouridine synthesis", "id": "GO:0031118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031118", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" } ], "pmid": "" }, { "name": "snRNA pseudouridine synthesis", "id": "GO:0031120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031120", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" } ], "pmid": "" }, { "name": "snoRNA guided rRNA pseudouridine synthesis", "id": "GO:0000454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000454", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" } ], "pmid": "" }, { "name": "box H/ACA snoRNP assembly", "id": "GO:0000493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000493", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" } ], "pmid": "" } ], "molecular_function": [ { "name": "box H/ACA snoRNA binding", "id": "GO:0034513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034513", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32495-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Thr120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002367", "url": "https://www.yeastgenome.org/locus/S000002367" }, { "database": "iPTMnet", "id": "P32495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32495" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32495-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002367", "url": "https://www.yeastgenome.org/locus/S000002367" }, { "database": "iPTMnet", "id": "P32495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32495" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32495-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002367", "url": "https://www.yeastgenome.org/locus/S000002367" }, { "database": "iPTMnet", "id": "P32495", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32495" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32495-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Val56", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "K", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" }, { "database": "PubMed", "id": "11433018", "url": "https://glygen.org/publication/PubMed/11433018" } ] } ] }, { "uniprot_canonical_ac": "P32495-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Gly59", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "Significant growth impairment at 30 and 37 degrees Celsius. Impaired association with H/ACA snoRNAs.", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" }, { "database": "PubMed", "id": "11433018", "url": "https://glygen.org/publication/PubMed/11433018" } ] } ] }, { "uniprot_canonical_ac": "P32495-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Arg68", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" }, { "database": "PubMed", "id": "11433018", "url": "https://glygen.org/publication/PubMed/11433018" } ] } ] }, { "uniprot_canonical_ac": "P32495-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Asp80", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P32495", "url": "https://www.uniprot.org/uniprotkb/P32495" }, { "database": "PubMed", "id": "11433018", "url": "https://glygen.org/publication/PubMed/11433018" } ] } ] } ], "record_id": "P32495-1" }, { "uniprot_canonical_ac": "P32496-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32496", "url": "https://www.uniprot.org/uniprotkb/P32496" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 274, "chemical_mass": 31919.0, "gene_names": "RPN12;NIN1;RPN12", "protein_name": "26S proteasome regulatory subunit RPN12", "disease": [], "cellular_component": [ { "name": "proteasome storage granule", "id": "GO:0034515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034515", "evidence": [ { "database": "UniProtKB", "id": "P32496", "url": "https://www.uniprot.org/uniprotkb/P32496" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32496", "url": "https://www.uniprot.org/uniprotkb/P32496" } ], "pmid": "" }, { "name": "proteasome regulatory particle, lid subcomplex", "id": "GO:0008541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008541", "evidence": [ { "database": "UniProtKB", "id": "P32496", "url": "https://www.uniprot.org/uniprotkb/P32496" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P32496", "url": "https://www.uniprot.org/uniprotkb/P32496" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P32496", "url": "https://www.uniprot.org/uniprotkb/P32496" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32496-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001948", "url": "https://www.yeastgenome.org/locus/S000001948" }, { "database": "iPTMnet", "id": "P32496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32496" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32496-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Thr257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001948", "url": "https://www.yeastgenome.org/locus/S000001948" }, { "database": "iPTMnet", "id": "P32496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32496" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32496-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32496" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001948", "url": "https://www.yeastgenome.org/locus/S000001948" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32496-1" }, { "uniprot_canonical_ac": "P32499-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 720, "chemical_mass": 77881.0, "gene_names": "NUP2;L8300.9;NUP2", "protein_name": "Nucleoporin NUP2", "disease": [ { "disease_id": "DOID:0050905", "name": "inflammatory myofibroblastic tumor", "description": "A mesenchymal cell neoplasm that has_material_basis_in myofibroblastic cells admixed with inflammatory cells.", "url": "https://disease-ontology.org/term/DOID:0050905", "evidence": [ { "id": "0050905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050905" } ], "weight": 0.0 }, { "disease_id": "DOID:936", "name": "brain disease", "description": "A central nervous system disease that is located_in the brain.", "url": "https://disease-ontology.org/term/DOID:936", "evidence": [ { "id": "936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:936" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 } ], "biological_process": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "mRNA export from nucleus in response to heat stress", "id": "GO:0031990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031990", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000973", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "protein localization to nuclear inner membrane", "id": "GO:0036228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036228", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "NLS-bearing protein import into nucleus", "id": "GO:0006607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006607", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000972", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" } ], "molecular_function": [ { "name": "importin-alpha family protein binding", "id": "GO:0061676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061676", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore nuclear basket", "id": "GO:0044615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044615", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "nuclear pore cytoplasmic filaments", "id": "GO:0044614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044614", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" }, { "name": "NLS-dependent protein nuclear import complex", "id": "GO:0042564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042564", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32499-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Thr470", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 470, "start_aa": "Thr", "end_pos": 470, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr470", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Ser475", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 475, "start_aa": "Ser", "end_pos": 475, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser475", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "512", "end_pos": "512", "site_lbl": "Ser512", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 512, "start_aa": "Ser", "end_pos": 512, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser512", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "516", "end_pos": "516", "site_lbl": "Ser516", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 516, "start_aa": "Ser", "end_pos": 516, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser516", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Ser523", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 523, "start_aa": "Ser", "end_pos": 523, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser523", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "525", "end_pos": "525", "site_lbl": "Ser525", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 525, "start_aa": "Ser", "end_pos": 525, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser525", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "537", "end_pos": "537", "site_lbl": "Ser537", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 537, "start_aa": "Ser", "end_pos": 537, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser537", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Ser538", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 538, "start_aa": "Ser", "end_pos": 538, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser538", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "540", "end_pos": "540", "site_lbl": "Ser540", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 540, "start_aa": "Ser", "end_pos": 540, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser540", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Ser544", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 544, "start_aa": "Ser", "end_pos": 544, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser544", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "547", "end_pos": "547", "site_lbl": "Ser547", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 547, "start_aa": "Ser", "end_pos": 547, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser547", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "561", "end_pos": "561", "site_lbl": "Ser561", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 561, "start_aa": "Ser", "end_pos": 561, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser561", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "568", "end_pos": "568", "site_lbl": "Ser568", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 568, "start_aa": "Ser", "end_pos": 568, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser568", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "572", "end_pos": "572", "site_lbl": "Ser572", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 572, "start_aa": "Ser", "end_pos": 572, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser572", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "581", "end_pos": "581", "site_lbl": "Ser581", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 581, "start_aa": "Ser", "end_pos": 581, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser581", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32499" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Tyr15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Ser163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ser164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Ser165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "15972895", "url": "https://glygen.org/publication/PubMed/15972895" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Ser190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "15972895", "url": "https://glygen.org/publication/PubMed/15972895" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Ser223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Ser232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Ser248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Ser250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Ser251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Ser295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Ser301", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Ser312", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Ser316", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Ser317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Thr324", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "342", "end_pos": "342", "site_lbl": "Ser342", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Ser343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "345", "end_pos": "345", "site_lbl": "Ser345", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Ser348", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Ser351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Ser358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Thr361", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "23645671", "url": "https://glygen.org/publication/PubMed/23645671" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Ser368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Ser387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Thr392", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Ser394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Ser439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Ser455", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Ser458", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Thr494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Ser498", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Thr515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Thr529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Thr539", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Ser553", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Thr564", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "573", "end_pos": "573", "site_lbl": "Thr573", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "574", "end_pos": "574", "site_lbl": "Thr574", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Thr577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Thr585", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "590", "end_pos": "590", "site_lbl": "Thr590", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32499", "url": "https://www.uniprot.org/uniprotkb/P32499" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "618", "end_pos": "618", "site_lbl": "Thr618", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Thr76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32499-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32499" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004327", "url": "https://www.yeastgenome.org/locus/S000004327" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32499-1" }, { "uniprot_canonical_ac": "P32500-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 655, "chemical_mass": 74134.0, "gene_names": "NDC1;NDC1", "protein_name": "Nucleoporin NDC1", "disease": [], "cellular_component": [ { "name": "nuclear pore transmembrane ring", "id": "GO:0070762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070762", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear pore organization", "id": "GO:0006999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006999", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" }, { "name": "spindle pole body duplication", "id": "GO:0030474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030474", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" }, { "name": "spindle pole body localization", "id": "GO:0070631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070631", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" }, { "name": "spindle pole body-nuclear membrane anchor activity", "id": "GO:0106166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106166", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32500-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004493", "url": "https://www.yeastgenome.org/locus/S000004493" }, { "database": "iPTMnet", "id": "P32500", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32500" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32500-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Ser401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32500", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32500" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004493", "url": "https://www.yeastgenome.org/locus/S000004493" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32500-1", "start_pos": "409", "end_pos": "409", "site_lbl": "Thr409", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32500", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32500" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004493", "url": "https://www.yeastgenome.org/locus/S000004493" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32500-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Ser412", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32500", "url": "https://www.uniprot.org/uniprotkb/P32500" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32500", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32500" }, { "database": "SGD", "id": "S000004493", "url": "https://www.yeastgenome.org/locus/S000004493" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32500-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Ser492", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004493", "url": "https://www.yeastgenome.org/locus/S000004493" }, { "database": "iPTMnet", "id": "P32500", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32500" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32500-1" }, { "uniprot_canonical_ac": "P32504-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 956, "chemical_mass": 111917.0, "gene_names": "CBF2;CBF2;CBF3A;CEP2;CSL5;CTF14;NDC10", "protein_name": "Centromere DNA-binding protein complex CBF3 subunit A", "disease": [], "biological_process": [ { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "septin ring assembly", "id": "GO:0000921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000921", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "mitotic spindle elongation", "id": "GO:0000022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000022", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding, bending", "id": "GO:0008301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008301", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "centromeric DNA binding", "id": "GO:0019237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019237", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "condensed chromosome, centromeric region", "id": "GO:0000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000779", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" }, { "name": "CBF3 complex", "id": "GO:0031518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031518", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32504-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Thr64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 64, "start_aa": "Thr", "end_pos": 64, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr64", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "559", "end_pos": "559", "site_lbl": "Ser559", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "566", "end_pos": "566", "site_lbl": "Ser566", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "664", "end_pos": "664", "site_lbl": "Thr664", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "665", "end_pos": "665", "site_lbl": "Ser665", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "700", "end_pos": "700", "site_lbl": "Ser700", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "706", "end_pos": "706", "site_lbl": "Tyr706", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32504", "url": "https://www.uniprot.org/uniprotkb/P32504" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Ser715", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "821", "end_pos": "821", "site_lbl": "Ser821", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "823", "end_pos": "823", "site_lbl": "Thr823", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "825", "end_pos": "825", "site_lbl": "Ser825", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "827", "end_pos": "827", "site_lbl": "Ser827", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "836", "end_pos": "836", "site_lbl": "Ser836", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "837", "end_pos": "837", "site_lbl": "Tyr837", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "838", "end_pos": "838", "site_lbl": "Thr838", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" }, { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32504-1", "start_pos": "890", "end_pos": "890", "site_lbl": "Tyr890", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32504", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32504" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003372", "url": "https://www.yeastgenome.org/locus/S000003372" } ] } ] } ], "record_id": "P32504-1" }, { "uniprot_canonical_ac": "P32505-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 525, "chemical_mass": 58321.0, "gene_names": "NAB2;NAB2", "protein_name": "Nuclear polyadenylated RNA-binding protein NAB2", "disease": [ { "disease_id": "DOID:0060308", "name": "autosomal recessive intellectual developmental disorder", "description": "A intellectual disability characterized by an autosomal recessive inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0060308", "evidence": [ { "id": "0060308", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060308" } ], "weight": 0.0 }, { "disease_id": "DOID:0081217", "name": "autosomal recessive intellectual developmental disorder 56", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the ZC3H14 gene on chromosome 14q31.", "url": "https://disease-ontology.org/term/DOID:0081217", "evidence": [ { "id": "0081217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081217" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 } ], "biological_process": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase III", "id": "GO:0045945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045945", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900152", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "spliceosome-depend formation of circular RNA", "id": "GO:0160091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160091", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "5S rRNA binding", "id": "GO:0008097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008097", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "7S RNA binding", "id": "GO:0008312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008312", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32505-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Thr178", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 178, "start_aa": "Thr", "end_pos": 178, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr178", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "Q00772-1", "kinase_gene_name": "SLT2", "evidence": [ { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "20823268", "url": "https://glygen.org/publication/PubMed/20823268" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "20823268", "url": "https://glygen.org/publication/PubMed/20823268" }, { "database": "SGD", "id": "S000003090", "url": "https://www.yeastgenome.org/locus/S000003090" } ] } ] }, { "uniprot_canonical_ac": "P32505-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Ser180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "Q00772-1", "kinase_gene_name": "SLT2", "evidence": [ { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "20823268", "url": "https://glygen.org/publication/PubMed/20823268" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "20823268", "url": "https://glygen.org/publication/PubMed/20823268" }, { "database": "SGD", "id": "S000003090", "url": "https://www.yeastgenome.org/locus/S000003090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32505-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Ser249", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003090", "url": "https://www.yeastgenome.org/locus/S000003090" }, { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32505-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Thr254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32505", "url": "https://www.uniprot.org/uniprotkb/P32505" }, { "database": "PubMed", "id": "33856219", "url": "https://glygen.org/publication/PubMed/33856219" }, { "database": "SGD", "id": "S000003090", "url": "https://www.yeastgenome.org/locus/S000003090" }, { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32505-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Thr256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003090", "url": "https://www.yeastgenome.org/locus/S000003090" }, { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32505-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003090", "url": "https://www.yeastgenome.org/locus/S000003090" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32505-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003090", "url": "https://www.yeastgenome.org/locus/S000003090" }, { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32505-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Tyr468", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003090", "url": "https://www.yeastgenome.org/locus/S000003090" }, { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32505-1", "start_pos": "514", "end_pos": "514", "site_lbl": "Ser514", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003090", "url": "https://www.yeastgenome.org/locus/S000003090" }, { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32505-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Thr7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003090", "url": "https://www.yeastgenome.org/locus/S000003090" }, { "database": "iPTMnet", "id": "P32505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32505" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32505-1" }, { "uniprot_canonical_ac": "P32521-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1480, "chemical_mass": 160267.0, "gene_names": "PAN1;DIM2;MDP3;MIP3;PAN1;YIB6C", "protein_name": "Actin cytoskeleton-regulatory complex protein PAN1", "disease": [ { "disease_id": "DOID:0110734", "name": "neurodegeneration with brain iron accumulation", "description": "A neurodegenerative disease characterized by progressive iron accumulation in the basal ganglia and other regions of the brain, resulting in extrapyramidal movements, such as parkinsonism and dystonia.", "url": "https://disease-ontology.org/term/DOID:0110734", "evidence": [ { "id": "0110734", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110734" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "Arp2/3 complex binding", "id": "GO:0071933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071933", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "actin cytoskeleton-regulatory complex", "id": "GO:1990964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990964", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "positive regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:2000601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000601", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "actin cortical patch assembly", "id": "GO:0000147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000147", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "axial cellular bud site selection", "id": "GO:0007120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007120", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "bipolar cellular bud site selection", "id": "GO:0007121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007121", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32521-1", "start_pos": "1098", "end_pos": "1098", "site_lbl": "Thr1098", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1098, "start_aa": "Thr", "end_pos": 1098, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1098", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1104", "end_pos": "1104", "site_lbl": "Thr1104", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1104, "start_aa": "Thr", "end_pos": 1104, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1104", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1110", "end_pos": "1110", "site_lbl": "Thr1110", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1110, "start_aa": "Thr", "end_pos": 1110, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1110", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1116", "end_pos": "1116", "site_lbl": "Thr1116", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1116, "start_aa": "Thr", "end_pos": 1116, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1116", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1122", "end_pos": "1122", "site_lbl": "Thr1122", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1122, "start_aa": "Thr", "end_pos": 1122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1122", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1219", "end_pos": "1219", "site_lbl": "Ser1219", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1219, "start_aa": "Ser", "end_pos": 1219, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1219", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1225", "end_pos": "1225", "site_lbl": "Thr1225", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1225, "start_aa": "Thr", "end_pos": 1225, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1225", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "22890988", "url": "https://glygen.org/publication/PubMed/22890988" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1232", "end_pos": "1232", "site_lbl": "Ser1232", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1232, "start_aa": "Ser", "end_pos": 1232, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1232", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1237", "end_pos": "1237", "site_lbl": "Ser1237", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1237, "start_aa": "Ser", "end_pos": 1237, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1237", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1250", "end_pos": "1250", "site_lbl": "Ser1250", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1250, "start_aa": "Ser", "end_pos": 1250, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1250", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1252", "end_pos": "1252", "site_lbl": "Ser1252", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1252, "start_aa": "Ser", "end_pos": 1252, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1252", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1253", "end_pos": "1253", "site_lbl": "Ser1253", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1253, "start_aa": "Ser", "end_pos": 1253, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1253", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1254", "end_pos": "1254", "site_lbl": "Thr1254", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1254, "start_aa": "Thr", "end_pos": 1254, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1254", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1255", "end_pos": "1255", "site_lbl": "Ser1255", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1255, "start_aa": "Ser", "end_pos": 1255, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1255", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1256", "end_pos": "1256", "site_lbl": "Thr1256", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1256, "start_aa": "Thr", "end_pos": 1256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1256", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "699", "end_pos": "699", "site_lbl": "Thr699", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 699, "start_aa": "Thr", "end_pos": 699, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr699", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "709", "end_pos": "709", "site_lbl": "Ser709", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 709, "start_aa": "Ser", "end_pos": 709, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser709", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "744", "end_pos": "744", "site_lbl": "Ser744", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 744, "start_aa": "Ser", "end_pos": 744, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser744", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "745", "end_pos": "745", "site_lbl": "Ser745", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 745, "start_aa": "Ser", "end_pos": 745, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser745", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "747", "end_pos": "747", "site_lbl": "Ser747", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 747, "start_aa": "Ser", "end_pos": 747, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser747", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "748", "end_pos": "748", "site_lbl": "Ser748", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 748, "start_aa": "Ser", "end_pos": 748, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser748", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "750", "end_pos": "750", "site_lbl": "Ser750", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 750, "start_aa": "Ser", "end_pos": 750, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser750", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "991", "end_pos": "991", "site_lbl": "Ser991", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 991, "start_aa": "Ser", "end_pos": 991, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser991", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "992", "end_pos": "992", "site_lbl": "Ser992", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 992, "start_aa": "Ser", "end_pos": 992, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser992", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32521", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32521" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1001", "end_pos": "1001", "site_lbl": "Ser1001", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1003", "end_pos": "1003", "site_lbl": "Ser1003", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1005", "end_pos": "1005", "site_lbl": "Ser1005", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1006", "end_pos": "1006", "site_lbl": "Tyr1006", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1007", "end_pos": "1007", "site_lbl": "Ser1007", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1045", "end_pos": "1045", "site_lbl": "Ser1045", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1049", "end_pos": "1049", "site_lbl": "Ser1049", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1072", "end_pos": "1072", "site_lbl": "Thr1072", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1135", "end_pos": "1135", "site_lbl": "Ser1135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1180", "end_pos": "1180", "site_lbl": "Ser1180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1185", "end_pos": "1185", "site_lbl": "Thr1185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1281", "end_pos": "1281", "site_lbl": "Ser1281", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1319", "end_pos": "1319", "site_lbl": "Ser1319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "1321", "end_pos": "1321", "site_lbl": "Thr1321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Thr148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Thr170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Thr221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Thr241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Thr398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "415", "end_pos": "415", "site_lbl": "Thr415", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "428", "end_pos": "428", "site_lbl": "Thr428", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Thr452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Thr473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "480", "end_pos": "480", "site_lbl": "Thr480", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Thr487", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Thr504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "513", "end_pos": "513", "site_lbl": "Thr513", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Thr544", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Thr551", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "566", "end_pos": "566", "site_lbl": "Thr566", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "13679512", "url": "https://glygen.org/publication/PubMed/13679512" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Thr570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "15711538", "url": "https://glygen.org/publication/PubMed/15711538" }, { "database": "PubMed", "id": "17303466", "url": "https://glygen.org/publication/PubMed/17303466" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "9885245", "url": "https://glygen.org/publication/PubMed/9885245" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "592", "end_pos": "592", "site_lbl": "Ser592", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Ser621", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "685", "end_pos": "685", "site_lbl": "Ser685", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "718", "end_pos": "718", "site_lbl": "Tyr718", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "757", "end_pos": "757", "site_lbl": "Ser757", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "758", "end_pos": "758", "site_lbl": "Ser758", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "759", "end_pos": "759", "site_lbl": "Ser759", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "767", "end_pos": "767", "site_lbl": "Ser767", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "887", "end_pos": "887", "site_lbl": "Ser887", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "896", "end_pos": "896", "site_lbl": "Ser896", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "901", "end_pos": "901", "site_lbl": "Ser901", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "908", "end_pos": "908", "site_lbl": "Ser908", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "931", "end_pos": "931", "site_lbl": "Ser931", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "981", "end_pos": "981", "site_lbl": "Ser981", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "983", "end_pos": "983", "site_lbl": "Thr983", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "985", "end_pos": "985", "site_lbl": "Ser985", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "986", "end_pos": "986", "site_lbl": "Ser986", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "993", "end_pos": "993", "site_lbl": "Thr993", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32521-1", "start_pos": "995", "end_pos": "995", "site_lbl": "Thr995", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32521", "url": "https://www.uniprot.org/uniprotkb/P32521" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32521" }, { "database": "SGD", "id": "S000001445", "url": "https://www.yeastgenome.org/locus/S000001445" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32521-1" }, { "uniprot_canonical_ac": "P32525-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32525", "url": "https://www.uniprot.org/uniprotkb/P32525" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 599, "chemical_mass": 68464.0, "gene_names": "ECM25;ECM25;J0325", "protein_name": "Protein ECM25", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "P32525", "url": "https://www.uniprot.org/uniprotkb/P32525" } ], "pmid": "" }, { "name": "actinin binding", "id": "GO:0042805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042805", "evidence": [ { "database": "UniProtKB", "id": "P32525", "url": "https://www.uniprot.org/uniprotkb/P32525" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32525", "url": "https://www.uniprot.org/uniprotkb/P32525" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "P32525", "url": "https://www.uniprot.org/uniprotkb/P32525" } ], "pmid": "" }, { "name": "regulation of cellular response to stress", "id": "GO:0080135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080135", "evidence": [ { "database": "UniProtKB", "id": "P32525", "url": "https://www.uniprot.org/uniprotkb/P32525" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "P32525", "url": "https://www.uniprot.org/uniprotkb/P32525" } ], "pmid": "" }, { "name": "regulation of unidimensional cell growth", "id": "GO:0051510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051510", "evidence": [ { "database": "UniProtKB", "id": "P32525", "url": "https://www.uniprot.org/uniprotkb/P32525" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32525-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Ser363", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Ser364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Ser390", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Ser400", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Ser402", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Ser408", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Thr410", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "411", "end_pos": "411", "site_lbl": "Ser411", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "413", "end_pos": "413", "site_lbl": "Thr413", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "414", "end_pos": "414", "site_lbl": "Tyr414", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "415", "end_pos": "415", "site_lbl": "Thr415", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "422", "end_pos": "422", "site_lbl": "Thr422", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Ser435", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Ser436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Thr458", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Ser461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Thr463", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Ser470", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Ser471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "476", "end_pos": "476", "site_lbl": "Ser476", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Thr481", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Ser483", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "486", "end_pos": "486", "site_lbl": "Ser486", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Ser492", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "493", "end_pos": "493", "site_lbl": "Ser493", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32525-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Thr494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32525", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32525" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003737", "url": "https://www.yeastgenome.org/locus/S000003737" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32525-1" }, { "uniprot_canonical_ac": "P32527-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 433, "chemical_mass": 49020.0, "gene_names": "ZUO1;ZUO1", "protein_name": "Zuotin", "disease": [], "biological_process": [ { "name": "'de novo' cotranslational protein folding", "id": "GO:0051083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051083", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "translational frameshifting", "id": "GO:0006452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006452", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "G-quadruplex DNA formation", "id": "GO:0071919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071919", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "G-quadruplex DNA binding", "id": "GO:0051880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051880", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32527-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Thr202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Ser244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Ser281", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Thr375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Thr376", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Ser426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Thr48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Thr63", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003517", "url": "https://www.yeastgenome.org/locus/S000003517" }, { "database": "iPTMnet", "id": "P32527", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32527" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32527-1", "start_pos": "128", "end_pos": "128", "site_lbl": "His128", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Q", "comment": "Loss of function, but still forms a heterodimer with SSZ1 and associates with ribosomes.", "evidence": [ { "database": "UniProtKB", "id": "P32527", "url": "https://www.uniprot.org/uniprotkb/P32527" }, { "database": "PubMed", "id": "11929994", "url": "https://glygen.org/publication/PubMed/11929994" } ] } ] } ], "record_id": "P32527-1" }, { "uniprot_canonical_ac": "P32528-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32528", "url": "https://www.uniprot.org/uniprotkb/P32528" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1835, "chemical_mass": 201832.0, "gene_names": "DUR1,2;YBR1448", "protein_name": "Urea amidolyase", "disease": [ { "disease_id": "DOID:0080579", "name": "3-methylcrotonyl-CoA carboxylase 1 deficiency", "description": "A 3-Methylcrotonyl-CoA carboxylase deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding the alpha subunit of 3-methylcrotonyl-CoA carboxylase on chromosome 3q27.", "url": "https://disease-ontology.org/term/DOID:0080579", "evidence": [ { "id": "0080579", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080579" } ], "weight": 0.0 }, { "disease_id": "DOID:14701", "name": "propionic acidemia", "description": "An organic acidemia that involes a nonfunctional propionyl CoA carboxylase affecting conversion of amino acids and fats into sugar for energy.", "url": "https://disease-ontology.org/term/DOID:14701", "evidence": [ { "id": "14701", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14701" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32528", "url": "https://www.uniprot.org/uniprotkb/P32528" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32528", "url": "https://www.uniprot.org/uniprotkb/P32528" } ], "pmid": "" }, { "name": "allophanate hydrolase activity", "id": "GO:0004039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004039", "evidence": [ { "database": "UniProtKB", "id": "P32528", "url": "https://www.uniprot.org/uniprotkb/P32528" } ], "pmid": "" }, { "name": "urea carboxylase activity", "id": "GO:0004847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004847", "evidence": [ { "database": "UniProtKB", "id": "P32528", "url": "https://www.uniprot.org/uniprotkb/P32528" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32528", "url": "https://www.uniprot.org/uniprotkb/P32528" } ], "pmid": "" } ], "biological_process": [ { "name": "allantoin catabolic process", "id": "GO:0000256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000256", "evidence": [ { "database": "UniProtKB", "id": "P32528", "url": "https://www.uniprot.org/uniprotkb/P32528" } ], "pmid": "" }, { "name": "urea catabolic process", "id": "GO:0043419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043419", "evidence": [ { "database": "UniProtKB", "id": "P32528", "url": "https://www.uniprot.org/uniprotkb/P32528" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32528-1", "start_pos": "1393", "end_pos": "1393", "site_lbl": "Ser1393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000412", "url": "https://www.yeastgenome.org/locus/S000000412" }, { "database": "iPTMnet", "id": "P32528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32528-1", "start_pos": "1400", "end_pos": "1400", "site_lbl": "Ser1400", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32528" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P32528-1", "start_pos": "1411", "end_pos": "1411", "site_lbl": "Ser1411", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000412", "url": "https://www.yeastgenome.org/locus/S000000412" }, { "database": "iPTMnet", "id": "P32528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32528-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Thr141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000412", "url": "https://www.yeastgenome.org/locus/S000000412" }, { "database": "iPTMnet", "id": "P32528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32528-1", "start_pos": "1433", "end_pos": "1433", "site_lbl": "Ser1433", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000412", "url": "https://www.yeastgenome.org/locus/S000000412" }, { "database": "iPTMnet", "id": "P32528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32528-1", "start_pos": "1637", "end_pos": "1637", "site_lbl": "Ser1637", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000412", "url": "https://www.yeastgenome.org/locus/S000000412" }, { "database": "iPTMnet", "id": "P32528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32528-1", "start_pos": "1743", "end_pos": "1743", "site_lbl": "Ser1743", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000412", "url": "https://www.yeastgenome.org/locus/S000000412" }, { "database": "iPTMnet", "id": "P32528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32528-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Ser261", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000412", "url": "https://www.yeastgenome.org/locus/S000000412" }, { "database": "iPTMnet", "id": "P32528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32528-1", "start_pos": "803", "end_pos": "803", "site_lbl": "Ser803", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32528", "url": "https://www.uniprot.org/uniprotkb/P32528" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32528" }, { "database": "SGD", "id": "S000000412", "url": "https://www.yeastgenome.org/locus/S000000412" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32528-1", "start_pos": "982", "end_pos": "982", "site_lbl": "Ser982", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000412", "url": "https://www.yeastgenome.org/locus/S000000412" }, { "database": "iPTMnet", "id": "P32528", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32528" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32528-1" }, { "uniprot_canonical_ac": "P32558-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1035, "chemical_mass": 118630.0, "gene_names": "SPT16;CDC68;SPT16;SSF1", "protein_name": "FACT complex subunit SPT16", "disease": [ { "disease_id": "DOID:0070469", "name": "neurodevelopmental disorder with dysmorphic facies and thin corpus callosum", "description": "An autosomal dominant intellectual developmental disorder characterized by global developmental delay, impaired intellectual development with poor or absent speech and language, dysmorphic facial features, and corpus callosum abnormalities that has_material_basis_in heterozygous mutation in the SUPT16H gene on chromosome 14q11.2.", "url": "https://disease-ontology.org/term/DOID:0070469", "evidence": [ { "id": "0070469", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070469" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "nucleosome organization", "id": "GO:0034728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034728", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription elongation", "id": "GO:0032784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032784", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "regulation of sister chromatid cohesion", "id": "GO:0007063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007063", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "positive regulation of RNA polymerase II transcription preinitiation complex assembly", "id": "GO:0045899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045899", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": "GO:1902275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902275", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" } ], "cellular_component": [ { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" }, { "name": "FACT complex", "id": "GO:0035101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035101", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32558-1", "start_pos": "1011", "end_pos": "1011", "site_lbl": "Ser1011", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Thr213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "459", "end_pos": "459", "site_lbl": "Ser459", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Ser460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "467", "end_pos": "467", "site_lbl": "Ser467", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Ser473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Ser526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Ser542", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "559", "end_pos": "559", "site_lbl": "Ser559", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "598", "end_pos": "598", "site_lbl": "Ser598", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Ser601", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "602", "end_pos": "602", "site_lbl": "Ser602", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "606", "end_pos": "606", "site_lbl": "Ser606", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "637", "end_pos": "637", "site_lbl": "Ser637", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Ser715", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "765", "end_pos": "765", "site_lbl": "Ser765", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "768", "end_pos": "768", "site_lbl": "Ser768", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003175", "url": "https://www.yeastgenome.org/locus/S000003175" }, { "database": "iPTMnet", "id": "P32558", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32558" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "565", "end_pos": "565", "site_lbl": "Pro565", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "S", "comment": "In spt16-4; induces a spt phenotype characterized by depletion of many mRNAs; when associated with L-570.", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" }, { "database": "PubMed", "id": "11432837", "url": "https://glygen.org/publication/PubMed/11432837" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Pro570", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "In spt16-4; induces a spt phenotype characterized by depletion of many mRNAs; when associated with S-565.", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" }, { "database": "PubMed", "id": "11432837", "url": "https://glygen.org/publication/PubMed/11432837" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "836", "end_pos": "836", "site_lbl": "Gly836", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In cdc68-1; induces a spt phenotype characterized by depletion of many mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" }, { "database": "PubMed", "id": "9832518", "url": "https://glygen.org/publication/PubMed/9832518" } ] } ] }, { "uniprot_canonical_ac": "P32558-1", "start_pos": "920", "end_pos": "920", "site_lbl": "Pro920", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "In spt16-6; induces a spt phenotype characterized by depletion of many mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "P32558", "url": "https://www.uniprot.org/uniprotkb/P32558" }, { "database": "PubMed", "id": "11432837", "url": "https://glygen.org/publication/PubMed/11432837" } ] } ] } ], "record_id": "P32558-1" }, { "uniprot_canonical_ac": "P32566-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 505, "chemical_mass": 57079.0, "gene_names": "SMI1;G8553;KNR4;KTR4;SMI1", "protein_name": "Cell wall assembly regulator SMI1", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "pmid": "" }, { "name": "regulation of fungal-type cell wall biogenesis", "id": "GO:0032995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032995", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "pmid": "" }, { "name": "fungal-type cell wall beta-glucan biosynthetic process", "id": "GO:0070880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070880", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32566-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Thr196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Thr198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "16362369", "url": "https://glygen.org/publication/PubMed/16362369" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "16362369", "url": "https://glygen.org/publication/PubMed/16362369" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Ser350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Ser355", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Ser375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Thr376", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "21725298", "url": "https://glygen.org/publication/PubMed/21725298" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Ser381", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Ser387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Ser389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Ser394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Ser400", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32566", "url": "https://www.uniprot.org/uniprotkb/P32566" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Thr406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "409", "end_pos": "409", "site_lbl": "Ser409", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "415", "end_pos": "415", "site_lbl": "Thr415", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "418", "end_pos": "418", "site_lbl": "Thr418", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Ser488", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32566-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003461", "url": "https://www.yeastgenome.org/locus/S000003461" }, { "database": "iPTMnet", "id": "P32566", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32566-1" }, { "uniprot_canonical_ac": "P32567-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 862, "chemical_mass": 95031.0, "gene_names": "PAH1;PAH1;PAP1;SMP2;YM8520.14C", "protein_name": "Phosphatidic acid phosphohydrolase 1", "disease": [ { "disease_id": "DOID:0061224", "name": "Majeed syndrome", "description": "An autoinflammatory disease characterized by characterized by chronic recurrent multifocal osteomyelitis (CRMO) and congenital dyserythropoietic anemia that has_material_basis_in homozygous mutation in the LPIN2 gene on chromosome 18p11.", "url": "https://disease-ontology.org/term/DOID:0061224", "evidence": [ { "id": "0061224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061224" } ], "weight": 0.0 }, { "disease_id": "DOID:0080108", "name": "myoglobinuria", "description": "A myopathy that is characterized by an increased urinary excretion of myoglobin.", "url": "https://disease-ontology.org/term/DOID:0080108", "evidence": [ { "id": "0080108", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080108" } ], "weight": 0.0 }, { "disease_id": "DOID:11981", "name": "morbid obesity", "description": "", "url": "https://disease-ontology.org/term/DOID:11981", "evidence": [ { "id": "11981", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11981" } ], "weight": 0.0 }, { "disease_id": "DOID:3146", "name": "lipid metabolism disorder", "description": "An inherited metabolic disorder that involves the creation and degradation of lipids.", "url": "https://disease-ontology.org/term/DOID:3146", "evidence": [ { "id": "3146", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3146" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:811", "name": "lipodystrophy", "description": "A connective tissue disease that is characterized by marked reduction, absence, and/or the redistribution of adipose tissue.", "url": "https://disease-ontology.org/term/DOID:811", "evidence": [ { "id": "811", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:811" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "vacuole fusion, non-autophagic", "id": "GO:0042144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042144", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "fatty acid catabolic process", "id": "GO:0009062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009062", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "diacylglycerol biosynthetic process", "id": "GO:0006651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006651", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "triglyceride biosynthetic process", "id": "GO:0019432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019432", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "lipid droplet organization", "id": "GO:0034389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034389", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "aerobic respiration", "id": "GO:0009060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009060", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "plasmid maintenance", "id": "GO:0006276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006276", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" }, { "name": "phosphatidate phosphatase activity", "id": "GO:0008195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008195", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32567-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Thr281", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 281, "start_aa": "Thr", "end_pos": 281, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr281", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "16968695", "url": "https://glygen.org/publication/PubMed/16968695" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "21081492", "url": "https://glygen.org/publication/PubMed/21081492" }, { "database": "PubMed", "id": "22334681", "url": "https://glygen.org/publication/PubMed/22334681" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "16968695", "url": "https://glygen.org/publication/PubMed/16968695" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "21081492", "url": "https://glygen.org/publication/PubMed/21081492" }, { "database": "PubMed", "id": "22334681", "url": "https://glygen.org/publication/PubMed/22334681" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "31645435", "url": "https://glygen.org/publication/PubMed/31645435" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "35780834", "url": "https://glygen.org/publication/PubMed/35780834" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Thr163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "35780834", "url": "https://glygen.org/publication/PubMed/35780834" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Thr164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "35780834", "url": "https://glygen.org/publication/PubMed/35780834" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "16968695", "url": "https://glygen.org/publication/PubMed/16968695" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21081492", "url": "https://glygen.org/publication/PubMed/21081492" }, { "database": "PubMed", "id": "22334681", "url": "https://glygen.org/publication/PubMed/22334681" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Thr170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Thr175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Thr176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Thr203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Ser250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Thr274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "311", "end_pos": "311", "site_lbl": "Ser311", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Thr315", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Ser327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "421", "end_pos": "421", "site_lbl": "Thr421", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Ser475", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "31645435", "url": "https://glygen.org/publication/PubMed/31645435" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "505", "end_pos": "505", "site_lbl": "Ser505", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "511", "end_pos": "511", "site_lbl": "Ser511", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "31645435", "url": "https://glygen.org/publication/PubMed/31645435" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Thr522", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "35780834", "url": "https://glygen.org/publication/PubMed/35780834" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "546", "end_pos": "546", "site_lbl": "Ser546", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "594", "end_pos": "594", "site_lbl": "Thr594", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Thr596", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "597", "end_pos": "597", "site_lbl": "Ser597", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "602", "end_pos": "602", "site_lbl": "Ser602", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21081492", "url": "https://glygen.org/publication/PubMed/21081492" }, { "database": "PubMed", "id": "22334681", "url": "https://glygen.org/publication/PubMed/22334681" }, { "database": "PubMed", "id": "35780834", "url": "https://glygen.org/publication/PubMed/35780834" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "16968695", "url": "https://glygen.org/publication/PubMed/16968695" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "31645435", "url": "https://glygen.org/publication/PubMed/31645435" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "607", "end_pos": "607", "site_lbl": "Thr607", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "617", "end_pos": "617", "site_lbl": "Ser617", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Thr621", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "35780834", "url": "https://glygen.org/publication/PubMed/35780834" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "677", "end_pos": "677", "site_lbl": "Ser677", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "24876385", "url": "https://glygen.org/publication/PubMed/24876385" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "31645435", "url": "https://glygen.org/publication/PubMed/31645435" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "705", "end_pos": "705", "site_lbl": "Ser705", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "31645435", "url": "https://glygen.org/publication/PubMed/31645435" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "711", "end_pos": "711", "site_lbl": "Ser711", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "723", "end_pos": "723", "site_lbl": "Thr723", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "16968695", "url": "https://glygen.org/publication/PubMed/16968695" }, { "database": "PubMed", "id": "21081492", "url": "https://glygen.org/publication/PubMed/21081492" }, { "database": "PubMed", "id": "22334681", "url": "https://glygen.org/publication/PubMed/22334681" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "730", "end_pos": "730", "site_lbl": "Ser730", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "744", "end_pos": "744", "site_lbl": "Ser744", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "16968695", "url": "https://glygen.org/publication/PubMed/16968695" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21081492", "url": "https://glygen.org/publication/PubMed/21081492" }, { "database": "PubMed", "id": "22334681", "url": "https://glygen.org/publication/PubMed/22334681" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "748", "end_pos": "748", "site_lbl": "Ser748", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "16968695", "url": "https://glygen.org/publication/PubMed/16968695" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21081492", "url": "https://glygen.org/publication/PubMed/21081492" }, { "database": "PubMed", "id": "22334681", "url": "https://glygen.org/publication/PubMed/22334681" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "31645435", "url": "https://glygen.org/publication/PubMed/31645435" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "762", "end_pos": "762", "site_lbl": "Ser762", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "769", "end_pos": "769", "site_lbl": "Ser769", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "24876385", "url": "https://glygen.org/publication/PubMed/24876385" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "773", "end_pos": "773", "site_lbl": "Ser773", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "16968695", "url": "https://glygen.org/publication/PubMed/16968695" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "24876385", "url": "https://glygen.org/publication/PubMed/24876385" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "774", "end_pos": "774", "site_lbl": "Ser774", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "31645435", "url": "https://glygen.org/publication/PubMed/31645435" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "779", "end_pos": "779", "site_lbl": "Ser779", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "788", "end_pos": "788", "site_lbl": "Ser788", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "24876385", "url": "https://glygen.org/publication/PubMed/24876385" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "800", "end_pos": "800", "site_lbl": "Ser800", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "805", "end_pos": "805", "site_lbl": "Ser805", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "810", "end_pos": "810", "site_lbl": "Ser810", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "814", "end_pos": "814", "site_lbl": "Ser814", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "816", "end_pos": "816", "site_lbl": "Thr816", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "818", "end_pos": "818", "site_lbl": "Ser818", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "35780834", "url": "https://glygen.org/publication/PubMed/35780834" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "27044741", "url": "https://glygen.org/publication/PubMed/27044741" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "823", "end_pos": "823", "site_lbl": "Ser823", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "836", "end_pos": "836", "site_lbl": "Ser836", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "844", "end_pos": "844", "site_lbl": "Ser844", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "847", "end_pos": "847", "site_lbl": "Ser847", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32567", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32567" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004775", "url": "https://www.yeastgenome.org/locus/S000004775" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Val11", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Impairs membrane recruitment; when associated with A-8 and A-15.", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "20876142", "url": "https://glygen.org/publication/PubMed/20876142" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Trp15", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Impairs membrane recruitment; when associated with A-8 and A-11.", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "20876142", "url": "https://glygen.org/publication/PubMed/20876142" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Asp398", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "Impairs phosphatidate phosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "17971454", "url": "https://glygen.org/publication/PubMed/17971454" }, { "database": "PubMed", "id": "21422231", "url": "https://glygen.org/publication/PubMed/21422231" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Asp400", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "Impairs phosphatidate phosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "17971454", "url": "https://glygen.org/publication/PubMed/17971454" }, { "database": "PubMed", "id": "21422231", "url": "https://glygen.org/publication/PubMed/21422231" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "496", "end_pos": "496", "site_lbl": "Lys496", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolished acetylation by ESA1, leading to decreased diacylglycerol synthesis; when associated with R-801.", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "29765047", "url": "https://glygen.org/publication/PubMed/29765047" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "801", "end_pos": "801", "site_lbl": "Lys801", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolished acetylation by ESA1, leading to decreased diacylglycerol synthesis; when associated with R-496.", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "29765047", "url": "https://glygen.org/publication/PubMed/29765047" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Gly80", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "Impairs phosphatidate phosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "17971454", "url": "https://glygen.org/publication/PubMed/17971454" }, { "database": "PubMed", "id": "21422231", "url": "https://glygen.org/publication/PubMed/21422231" } ] } ] }, { "uniprot_canonical_ac": "P32567-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Leu8", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Impairs membrane recruitment; when associated with A-11 and A-15.", "evidence": [ { "database": "UniProtKB", "id": "P32567", "url": "https://www.uniprot.org/uniprotkb/P32567" }, { "database": "PubMed", "id": "20876142", "url": "https://glygen.org/publication/PubMed/20876142" } ] } ] } ], "record_id": "P32567-1" }, { "uniprot_canonical_ac": "P32568-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1501, "chemical_mass": 168767.0, "gene_names": "SNQ2;SNQ2;YD8119.16", "protein_name": "Protein SNQ2", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular monoatomic cation homeostasis", "id": "GO:0030003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030003", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" } ], "pmid": "" }, { "name": "xenobiotic detoxification by transmembrane export across the plasma membrane", "id": "GO:1990961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990961", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32568-1", "start_pos": "1401", "end_pos": "1401", "site_lbl": "Asn1401", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1401, "start_aa": "Asn", "end_pos": 1401, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1401", "evidence": [ { "id": "P32568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32568#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Asn273", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 273, "start_aa": "Asn", "end_pos": 273, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn273", "evidence": [ { "id": "P32568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32568#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Asn334", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 334, "start_aa": "Asn", "end_pos": 334, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn334", "evidence": [ { "id": "P32568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32568#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Asn518", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 518, "start_aa": "Asn", "end_pos": 518, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn518", "evidence": [ { "id": "P32568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32568#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "730", "end_pos": "730", "site_lbl": "Asn730", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 730, "start_aa": "Asn", "end_pos": 730, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn730", "evidence": [ { "id": "P32568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32568#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "874", "end_pos": "874", "site_lbl": "Asn874", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 874, "start_aa": "Asn", "end_pos": 874, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn874", "evidence": [ { "id": "P32568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32568#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Ser101", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "1149", "end_pos": "1149", "site_lbl": "Ser1149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "1153", "end_pos": "1153", "site_lbl": "Thr1153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Thr53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Thr59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Thr66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "833", "end_pos": "833", "site_lbl": "Ser833", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "834", "end_pos": "834", "site_lbl": "Ser834", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "836", "end_pos": "836", "site_lbl": "Ser836", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "837", "end_pos": "837", "site_lbl": "Ser837", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Ser86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32568", "url": "https://www.uniprot.org/uniprotkb/P32568" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Thr90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32568-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32568" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002418", "url": "https://www.yeastgenome.org/locus/S000002418" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32568-1" }, { "uniprot_canonical_ac": "P32569-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 687, "chemical_mass": 78476.0, "gene_names": "SRB4;MED17;SRB4", "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "disease": [ { "disease_id": "DOID:0111262", "name": "infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly", "description": "A brain disease characterized by cerebral and cerebellar atrophy, postnatal progressive microcephaly and intellectual disability that has_material_basis_in homozygous or compound heterozygous mutation in MED17 on 11q21.", "url": "https://disease-ontology.org/term/DOID:0111262", "evidence": [ { "id": "0111262", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111262" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II core promoter sequence-specific DNA binding", "id": "GO:0000979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000979", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "RNA polymerase II complex recruiting activity", "id": "GO:0001139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001139", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32569-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" }, { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" }, { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" }, { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" }, { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" }, { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Thr42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" }, { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" }, { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000824", "url": "https://www.yeastgenome.org/locus/S000000824" }, { "database": "iPTMnet", "id": "P32569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32569" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32569-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Gly353", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "C", "comment": "In SRB4-1; suppresses the phenotypic defects of an RNA polymerase IICTD truncation.", "evidence": [ { "database": "UniProtKB", "id": "P32569", "url": "https://www.uniprot.org/uniprotkb/P32569" }, { "database": "PubMed", "id": "8324825", "url": "https://glygen.org/publication/PubMed/8324825" } ] } ] } ], "record_id": "P32569-1" }, { "uniprot_canonical_ac": "P32570-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32570", "url": "https://www.uniprot.org/uniprotkb/P32570" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 121, "chemical_mass": 13863.0, "gene_names": "SRB6;MED22;SRB6;YBR1721", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P32570", "url": "https://www.uniprot.org/uniprotkb/P32570" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32570", "url": "https://www.uniprot.org/uniprotkb/P32570" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P32570", "url": "https://www.uniprot.org/uniprotkb/P32570" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P32570", "url": "https://www.uniprot.org/uniprotkb/P32570" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32570", "url": "https://www.uniprot.org/uniprotkb/P32570" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P32570", "url": "https://www.uniprot.org/uniprotkb/P32570" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "P32570", "url": "https://www.uniprot.org/uniprotkb/P32570" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "P32570", "url": "https://www.uniprot.org/uniprotkb/P32570" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32570-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 94, "start_aa": "Ser", "end_pos": 94, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser94", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32570", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32570" } ] } ] }, { "uniprot_canonical_ac": "P32570-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Asn86", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "K", "comment": "In SRB6-1; suppresses the phenotypic defects of an RNA polymerase IICTD truncation.", "evidence": [ { "database": "UniProtKB", "id": "P32570", "url": "https://www.uniprot.org/uniprotkb/P32570" }, { "database": "PubMed", "id": "8324825", "url": "https://glygen.org/publication/PubMed/8324825" } ] } ] } ], "record_id": "P32570-1" }, { "uniprot_canonical_ac": "P32571-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 926, "chemical_mass": 105192.0, "gene_names": "DOA4;D4270;DOA4;DOS1;MUT4;NPI2;SSV7;UBP4;YD8554.02C;YD9609.23C", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "disease": [], "biological_process": [ { "name": "ubiquitin recycling", "id": "GO:0010992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010992", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "intralumenal vesicle formation", "id": "GO:0070676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070676", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "free ubiquitin chain depolymerization", "id": "GO:0010995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010995", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32571-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Thr551", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 551, "start_aa": "Thr", "end_pos": 551, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr551", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" }, { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" }, { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "414", "end_pos": "414", "site_lbl": "Ser414", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "443", "end_pos": "443", "site_lbl": "Ser443", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "451", "end_pos": "451", "site_lbl": "Ser451", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" }, { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "496", "end_pos": "496", "site_lbl": "Ser496", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" }, { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Ser498", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "500", "end_pos": "500", "site_lbl": "Thr500", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" }, { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "502", "end_pos": "502", "site_lbl": "Thr502", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "636", "end_pos": "636", "site_lbl": "Ser636", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" }, { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "687", "end_pos": "687", "site_lbl": "Ser687", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002476", "url": "https://www.yeastgenome.org/locus/S000002476" }, { "database": "iPTMnet", "id": "P32571", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32571" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "571", "end_pos": "571", "site_lbl": "Cys571", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Impairs deubiquitination activity and protein sorting into the MVB pathway.", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" }, { "database": "PubMed", "id": "17446860", "url": "https://glygen.org/publication/PubMed/17446860" }, { "database": "PubMed", "id": "17376168", "url": "https://glygen.org/publication/PubMed/17376168" } ] }, { "sequence_org": "C", "sequence_mut": "S", "comment": "Impairs deubiquitination activity and protein sorting into the MVB pathway.", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" }, { "database": "PubMed", "id": "17446860", "url": "https://glygen.org/publication/PubMed/17446860" }, { "database": "PubMed", "id": "17376168", "url": "https://glygen.org/publication/PubMed/17376168" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "826", "end_pos": "826", "site_lbl": "Tyr826", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Impairs deubiquitination activity and binding to BRO1; when associated with A-827 and A-829.", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" }, { "database": "PubMed", "id": "17446860", "url": "https://glygen.org/publication/PubMed/17446860" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "827", "end_pos": "827", "site_lbl": "Pro827", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "Impairs deubiquitination activity and binding to BRO1; when associated with A-826 and A-829.", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" }, { "database": "PubMed", "id": "17446860", "url": "https://glygen.org/publication/PubMed/17446860" } ] } ] }, { "uniprot_canonical_ac": "P32571-1", "start_pos": "829", "end_pos": "829", "site_lbl": "Leu829", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Impairs deubiquitination activity and binding to BRO1; when associated with A-826 and A-827.", "evidence": [ { "database": "UniProtKB", "id": "P32571", "url": "https://www.uniprot.org/uniprotkb/P32571" }, { "database": "PubMed", "id": "17446860", "url": "https://glygen.org/publication/PubMed/17446860" } ] } ] } ], "record_id": "P32571-1" }, { "uniprot_canonical_ac": "P32573-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32573", "url": "https://www.uniprot.org/uniprotkb/P32573" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 292, "chemical_mass": 31109.0, "gene_names": "SPS19;N1362;SPS19;SPX19", "protein_name": "Peroxisomal 2,4-dienoyl-CoA reductase SPS19 [(3E)-enoyl-CoA-producing]", "disease": [], "molecular_function": [ { "name": "2,4-dienoyl-CoA reductase (NADPH) activity", "id": "GO:0008670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008670", "evidence": [ { "database": "UniProtKB", "id": "P32573", "url": "https://www.uniprot.org/uniprotkb/P32573" } ], "pmid": "" } ], "cellular_component": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P32573", "url": "https://www.uniprot.org/uniprotkb/P32573" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "P32573", "url": "https://www.uniprot.org/uniprotkb/P32573" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "P32573", "url": "https://www.uniprot.org/uniprotkb/P32573" } ], "pmid": "" }, { "name": "fatty acid catabolic process", "id": "GO:0009062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009062", "evidence": [ { "database": "UniProtKB", "id": "P32573", "url": "https://www.uniprot.org/uniprotkb/P32573" } ], "pmid": "" }, { "name": "ascospore formation", "id": "GO:0030437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030437", "evidence": [ { "database": "UniProtKB", "id": "P32573", "url": "https://www.uniprot.org/uniprotkb/P32573" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32573-1" }, { "uniprot_canonical_ac": "P32579-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 426, "chemical_mass": 46538.0, "gene_names": "SUA5;G1660;SUA5", "protein_name": "Threonylcarbamoyl-AMP synthase", "disease": [ { "disease_id": "DOID:0080694", "name": "Galloway-Mowat syndrome", "description": "A syndrome that is characterized by developmental delay, progressive microcephaly, cerebral and cerebellar atrophy with extrapyramidal involvement, and optic atrophy.", "url": "https://disease-ontology.org/term/DOID:0080694", "evidence": [ { "id": "0080694", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080694" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "single-stranded telomeric DNA binding", "id": "GO:0043047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043047", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "L-threonylcarbamoyladenylate synthase", "id": "GO:0061710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061710", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "tRNA threonylcarbamoyladenosine modification", "id": "GO:0002949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002949", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" }, { "name": "tRNA threonylcarbamoyladenosine metabolic process", "id": "GO:0070525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070525", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32579-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "F", "comment": "In SUA5-1; suppresses a translation initiation defect in a CYC1 allele at an aberrant ATG codon.", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" }, { "database": "PubMed", "id": "1325384", "url": "https://glygen.org/publication/PubMed/1325384" } ] } ] }, { "uniprot_canonical_ac": "P32579-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Arg174", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P32579-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P32579-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Asn198", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P32579-1", "start_pos": "234", "end_pos": "234", "site_lbl": "Ser234", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "V", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P32579-1", "start_pos": "423", "end_pos": "423", "site_lbl": "Cys423", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No phenotypes.", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" } ] } ] }, { "uniprot_canonical_ac": "P32579-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Reduces t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P32579-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Lys93", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] }, { "uniprot_canonical_ac": "P32579-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Arg95", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Severely impairs t(6)A37 formation.", "evidence": [ { "database": "UniProtKB", "id": "P32579", "url": "https://www.uniprot.org/uniprotkb/P32579" }, { "database": "PubMed", "id": "23620299", "url": "https://glygen.org/publication/PubMed/23620299" } ] } ] } ], "record_id": "P32579-1" }, { "uniprot_canonical_ac": "P32580-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 737, "chemical_mass": 84324.0, "gene_names": "SUV3;LPB2W;LPB2;SUV3", "protein_name": "ATP-dependent RNA helicase SUV3, mitochondrial", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" }, { "name": "mitochondrial degradosome", "id": "GO:0045025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045025", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial RNA catabolic process", "id": "GO:0000957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000957", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" }, { "name": "mitochondrial RNA 3'-end processing", "id": "GO:0000965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000965", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" }, { "name": "mitochondrial DNA replication", "id": "GO:0006264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006264", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" }, { "name": "Group I intron splicing", "id": "GO:0000372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000372", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32580-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Thr241", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 241, "start_aa": "Thr", "end_pos": 241, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr241", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32580-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005950", "url": "https://www.yeastgenome.org/locus/S000005950" }, { "database": "iPTMnet", "id": "P32580", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32580" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32580-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Val272", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "L", "comment": "In suv3-1; probably excised introns are less efficiently released.", "evidence": [ { "database": "UniProtKB", "id": "P32580", "url": "https://www.uniprot.org/uniprotkb/P32580" }, { "database": "PubMed", "id": "1379722", "url": "https://glygen.org/publication/PubMed/1379722" } ] } ] } ], "record_id": "P32580-1" }, { "uniprot_canonical_ac": "P32581-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 645, "chemical_mass": 73593.0, "gene_names": "IME2;IME2;J0817;SME1", "protein_name": "Meiosis induction protein kinase IME2/SME1", "disease": [ { "disease_id": "DOID:0060641", "name": "endocrine-cerebro-osteodysplasia syndrome", "description": "A syndrome that is characterized by multiple congenital defects in endocrine, cerebral, and skeletal systems leading to neonatal mortality; it has_material_basis_in mutation in the gene encoding intestinal cell kinase.", "url": "https://disease-ontology.org/term/DOID:0060641", "evidence": [ { "id": "0060641", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060641" } ], "weight": 0.0 }, { "disease_id": "DOID:0110380", "name": "retinitis pigmentosa 62", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the MAK gene on chromosome 6p24.2.", "url": "https://disease-ontology.org/term/DOID:0110380", "evidence": [ { "id": "0110380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110380" } ], "weight": 0.0 }, { "disease_id": "DOID:0111325", "name": "juvenile myoclonic epilepsy 10", "description": "A juvenile myoclonic epilepsy that has_material_basis_in heterozygous mutation in ICK on chromosome 6p12.1.", "url": "https://disease-ontology.org/term/DOID:0111325", "evidence": [ { "id": "0111325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111325" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "pmid": "" }, { "name": "regulation of meiotic nuclear division", "id": "GO:0040020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040020", "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P32581", "url": "https://www.uniprot.org/uniprotkb/P32581" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32581-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Thr242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P32581-1", "kinase_gene_name": "IME2", "evidence": [ { "database": "iPTMnet", "id": "P32581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32581" }, { "database": "PubMed", "id": "16684773", "url": "https://glygen.org/publication/PubMed/16684773" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32581" }, { "database": "PubMed", "id": "14612412", "url": "https://glygen.org/publication/PubMed/14612412" }, { "database": "PubMed", "id": "16684773", "url": "https://glygen.org/publication/PubMed/16684773" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003642", "url": "https://www.yeastgenome.org/locus/S000003642" }, { "database": "PubMed", "id": "35240051", "url": "https://glygen.org/publication/PubMed/35240051" } ] } ] }, { "uniprot_canonical_ac": "P32581-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Tyr244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32581" }, { "database": "PubMed", "id": "14612412", "url": "https://glygen.org/publication/PubMed/14612412" }, { "database": "PubMed", "id": "16684773", "url": "https://glygen.org/publication/PubMed/16684773" }, { "database": "PubMed", "id": "20543984", "url": "https://glygen.org/publication/PubMed/20543984" }, { "database": "SGD", "id": "S000003642", "url": "https://www.yeastgenome.org/locus/S000003642" } ] } ] }, { "uniprot_canonical_ac": "P32581-1", "start_pos": "520", "end_pos": "520", "site_lbl": "Ser520", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32581" }, { "database": "PubMed", "id": "16684773", "url": "https://glygen.org/publication/PubMed/16684773" }, { "database": "SGD", "id": "S000003642", "url": "https://www.yeastgenome.org/locus/S000003642" } ] } ] }, { "uniprot_canonical_ac": "P32581-1", "start_pos": "625", "end_pos": "625", "site_lbl": "Ser625", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32581", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32581" }, { "database": "PubMed", "id": "16684773", "url": "https://glygen.org/publication/PubMed/16684773" }, { "database": "SGD", "id": "S000003642", "url": "https://www.yeastgenome.org/locus/S000003642" } ] } ] } ], "record_id": "P32581-1" }, { "uniprot_canonical_ac": "P32582-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 507, "chemical_mass": 56022.0, "gene_names": "CYS4;CYS4;G6667;NHS5;STR4;VMA41", "protein_name": "Cystathionine beta-synthase", "disease": [ { "disease_id": "DOID:0050731", "name": "vitamin B12 deficiency", "description": "A vitamin metabolic disorder that results from low blood levels of vitamin B12.", "url": "https://disease-ontology.org/term/DOID:0050731", "evidence": [ { "id": "0050731", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050731" } ], "weight": 0.0 }, { "disease_id": "DOID:0080074", "name": "neural tube defect", "description": "A physical disorder characterized by incomplete closure of the neural tube.", "url": "https://disease-ontology.org/term/DOID:0080074", "evidence": [ { "id": "0080074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080074" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:9263", "name": "homocystinuria", "description": "An amino acid metabolic disorder that involves an accumulation of homocysteine in the serum and an increased excretion of homocysteine in the urine.", "url": "https://disease-ontology.org/term/DOID:9263", "evidence": [ { "id": "9263", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9263" } ], "weight": 0.0 }, { "disease_id": "DOID:9279", "name": "hyperhomocysteinemia", "description": "An amino acid metabolic disorder that involves an abnormally large level of homocysteine in the blood.", "url": "https://disease-ontology.org/term/DOID:9279", "evidence": [ { "id": "9279", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9279" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "pmid": "" }, { "name": "cystathionine beta-synthase activity", "id": "GO:0004122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004122", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "pmid": "" } ], "biological_process": [ { "name": "traversing start control point of mitotic cell cycle", "id": "GO:0007089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007089", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "pmid": "" }, { "name": "transsulfuration", "id": "GO:0019346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019346", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "pmid": "" }, { "name": "cysteine biosynthetic process from serine", "id": "GO:0006535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006535", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "pmid": "" }, { "name": "cysteine biosynthetic process via cystathionine", "id": "GO:0019343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019343", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "pmid": "" }, { "name": "hydrogen sulfide biosynthetic process", "id": "GO:0070814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070814", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32582-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Thr81", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 81, "start_aa": "Thr", "end_pos": 81, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr81", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Thr126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Thr128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Thr197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Thr200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Ser350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Ser351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Ser356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Ser424", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32582", "url": "https://www.uniprot.org/uniprotkb/P32582" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "428", "end_pos": "428", "site_lbl": "Ser428", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "451", "end_pos": "451", "site_lbl": "Ser451", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Ser473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32582-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003387", "url": "https://www.yeastgenome.org/locus/S000003387" }, { "database": "iPTMnet", "id": "P32582", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32582" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32582-1" }, { "uniprot_canonical_ac": "P32584-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 239, "chemical_mass": 27888.0, "gene_names": "STE14;D9461.1;STE14", "protein_name": "Protein-S-isoprenylcysteine O-methyltransferase", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" } ], "pmid": "" } ], "biological_process": [ { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" } ], "pmid": "" }, { "name": "C-terminal protein methylation", "id": "GO:0006481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006481", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" } ], "pmid": "" }, { "name": "peptide pheromone maturation", "id": "GO:0007323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007323", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity", "id": "GO:0004671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004671", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32584-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Gly132", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "Abolishes function.", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" }, { "database": "PubMed", "id": "11451995", "url": "https://glygen.org/publication/PubMed/11451995" } ] } ] }, { "uniprot_canonical_ac": "P32584-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Pro173", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "Abolishes function.", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" }, { "database": "PubMed", "id": "11451995", "url": "https://glygen.org/publication/PubMed/11451995" } ] } ] }, { "uniprot_canonical_ac": "P32584-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Glu213", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "D", "comment": "Abolishes function.", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" }, { "database": "PubMed", "id": "11451995", "url": "https://glygen.org/publication/PubMed/11451995" } ] } ] }, { "uniprot_canonical_ac": "P32584-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Glu214", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "D", "comment": "Abolishes function.", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" }, { "database": "PubMed", "id": "11451995", "url": "https://glygen.org/publication/PubMed/11451995" } ] }, { "sequence_org": "E", "sequence_mut": "Q", "comment": "Abolishes function.", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" }, { "database": "PubMed", "id": "11451995", "url": "https://glygen.org/publication/PubMed/11451995" } ] } ] }, { "uniprot_canonical_ac": "P32584-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Leu217", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "Abolishes function.", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" }, { "database": "PubMed", "id": "11451995", "url": "https://glygen.org/publication/PubMed/11451995" } ] } ] }, { "uniprot_canonical_ac": "P32584-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Gly31", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "Abolishes function.", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" }, { "database": "PubMed", "id": "11451995", "url": "https://glygen.org/publication/PubMed/11451995" } ] } ] }, { "uniprot_canonical_ac": "P32584-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Leu81", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "F", "comment": "Abolishes function.", "evidence": [ { "database": "UniProtKB", "id": "P32584", "url": "https://www.uniprot.org/uniprotkb/P32584" }, { "database": "PubMed", "id": "11451995", "url": "https://glygen.org/publication/PubMed/11451995" } ] } ] } ], "record_id": "P32584-1" }, { "uniprot_canonical_ac": "P32585-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 307, "chemical_mass": 34289.0, "gene_names": "SRB5;MED18;SRB5", "protein_name": "Mediator of RNA polymerase II transcription subunit 18", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" }, { "name": "transcription open complex formation at RNA polymerase II promoter", "id": "GO:0001113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001113", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription", "id": "GO:0006369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006369", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" }, { "name": "RNA polymerase II core promoter sequence-specific DNA binding", "id": "GO:0000979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000979", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32585-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003336", "url": "https://www.yeastgenome.org/locus/S000003336" }, { "database": "iPTMnet", "id": "P32585", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32585" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32585-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003336", "url": "https://www.yeastgenome.org/locus/S000003336" }, { "database": "iPTMnet", "id": "P32585", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32585" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32585-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "I", "comment": "In SRB5-1; suppresses the phenotypic defects of an RNA polymerase IICTD truncation.", "evidence": [ { "database": "UniProtKB", "id": "P32585", "url": "https://www.uniprot.org/uniprotkb/P32585" }, { "database": "PubMed", "id": "8324825", "url": "https://glygen.org/publication/PubMed/8324825" } ] } ] } ], "record_id": "P32585-1" }, { "uniprot_canonical_ac": "P32588-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 453, "chemical_mass": 50763.0, "gene_names": "PUB1;N2842;PUB1;RNP1", "protein_name": "Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1", "disease": [ { "disease_id": "DOID:0081380", "name": "amyotrophic lateral sclerosis type 26", "description": "An amyotrophic lateral sclerosis that is characterized by adult onset of upper and low motor neuron disease causing bulbar dysfunction and limb weakness and that has_material_basis_in heterozygous mutation in the TIA1 gene on chromosome 2p13.", "url": "https://disease-ontology.org/term/DOID:0081380", "evidence": [ { "id": "0081380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081380" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" }, { "name": "poly(U) RNA binding", "id": "GO:0008266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008266", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" } ], "biological_process": [ { "name": "translational termination", "id": "GO:0006415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006415", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" }, { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "P32588", "url": "https://www.uniprot.org/uniprotkb/P32588" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32588-1" }, { "uniprot_canonical_ac": "P32599-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 642, "chemical_mass": 71773.0, "gene_names": "SAC6;ABP67;SAC6;YD9302.04C", "protein_name": "Fimbrin", "disease": [ { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0112167", "name": "autosomal dominant nonsyndromic deafness 76", "description": "An autosomal dominant nonsyndromic deafness characterized by progressive or nonprogressive hearing loss with variable age at onset and typically is more severe at higher frequencies that has_material_basis_in heterozygous mutation in the PLS1 gene on chromosome 3q23.", "url": "https://disease-ontology.org/term/DOID:0112167", "evidence": [ { "id": "0112167", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112167" } ], "weight": 0.0 }, { "disease_id": "DOID:11476", "name": "osteoporosis", "description": "A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.", "url": "https://disease-ontology.org/term/DOID:11476", "evidence": [ { "id": "11476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11476" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:3827", "name": "congenital diaphragmatic hernia", "description": "A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs.", "url": "https://disease-ontology.org/term/DOID:3827", "evidence": [ { "id": "3827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3827" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "actin filament bundle", "id": "GO:0032432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032432", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "formin-nucleated actin cable assembly", "id": "GO:0070649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070649", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "P32599", "url": "https://www.uniprot.org/uniprotkb/P32599" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32599-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32599-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "27068241", "url": "https://glygen.org/publication/PubMed/27068241" }, { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32599-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Thr111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32599-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32599-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Thr131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32599-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32599-1", "start_pos": "366", "end_pos": "366", "site_lbl": "Thr366", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32599-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Ser466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32599-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Ser531", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32599-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Ser538", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32599-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Thr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002536", "url": "https://www.yeastgenome.org/locus/S000002536" }, { "database": "iPTMnet", "id": "P32599", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32599" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P32599-1" }, { "uniprot_canonical_ac": "P32602-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 292, "chemical_mass": 32803.0, "gene_names": "SEC17;RNS3;SEC17;YBL0505;YBL0517", "protein_name": "Alpha-soluble NSF attachment protein", "disease": [ { "disease_id": "DOID:0070393", "name": "developmental and epileptic encephalopathy 107", "description": "A developmental and epileptic encephalopathy characterized by onset of seizures in the first months of life, severe global developmental delay, profound intellectual disability, progressive microcephaly, and hypotonia that has_material_basis_in homozygous mutation in the NAPB gene on chromosome 20p11.", "url": "https://disease-ontology.org/term/DOID:0070393", "evidence": [ { "id": "0070393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070393" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 } ], "biological_process": [ { "name": "SNARE complex disassembly", "id": "GO:0035494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035494", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" }, { "name": "vacuole fusion, non-autophagic", "id": "GO:0042144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042144", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" }, { "name": "vesicle fusion with Golgi apparatus", "id": "GO:0048280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048280", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" } ], "molecular_function": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" }, { "name": "soluble NSF attachment protein activity", "id": "GO:0005483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005483", "evidence": [ { "database": "UniProtKB", "id": "P32602", "url": "https://www.uniprot.org/uniprotkb/P32602" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32602-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000146", "url": "https://www.yeastgenome.org/locus/S000000146" }, { "database": "iPTMnet", "id": "P32602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32602" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32602-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000146", "url": "https://www.yeastgenome.org/locus/S000000146" }, { "database": "iPTMnet", "id": "P32602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32602" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32602-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000146", "url": "https://www.yeastgenome.org/locus/S000000146" }, { "database": "iPTMnet", "id": "P32602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32602" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32602-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000146", "url": "https://www.yeastgenome.org/locus/S000000146" }, { "database": "iPTMnet", "id": "P32602", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32602" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32602-1" }, { "uniprot_canonical_ac": "P32603-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32603", "url": "https://www.uniprot.org/uniprotkb/P32603" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 445, "chemical_mass": 51809.0, "gene_names": "SPR1;SPR1;SSG1", "protein_name": "Sporulation-specific glucan 1,3-beta-glucosidase", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P32603", "url": "https://www.uniprot.org/uniprotkb/P32603" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P32603", "url": "https://www.uniprot.org/uniprotkb/P32603" } ], "pmid": "" }, { "name": "ascospore wall", "id": "GO:0005619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005619", "evidence": [ { "database": "UniProtKB", "id": "P32603", "url": "https://www.uniprot.org/uniprotkb/P32603" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P32603", "url": "https://www.uniprot.org/uniprotkb/P32603" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P32603", "url": "https://www.uniprot.org/uniprotkb/P32603" } ], "pmid": "" } ], "molecular_function": [ { "name": "glucan exo-1,3-beta-glucosidase activity", "id": "GO:0004338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004338", "evidence": [ { "database": "UniProtKB", "id": "P32603", "url": "https://www.uniprot.org/uniprotkb/P32603" } ], "pmid": "" } ], "biological_process": [ { "name": "glucan catabolic process", "id": "GO:0009251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009251", "evidence": [ { "database": "UniProtKB", "id": "P32603", "url": "https://www.uniprot.org/uniprotkb/P32603" } ], "pmid": "" }, { "name": "ascospore formation", "id": "GO:0030437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030437", "evidence": [ { "database": "UniProtKB", "id": "P32603", "url": "https://www.uniprot.org/uniprotkb/P32603" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "P32603", "url": "https://www.uniprot.org/uniprotkb/P32603" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32603-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Asn201", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 201, "start_aa": "Asn", "end_pos": 201, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn201", "evidence": [ { "id": "P32603", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32603#ptm_processing" } ] } ] } ], "record_id": "P32603-1" }, { "uniprot_canonical_ac": "P32604-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 452, "chemical_mass": 52595.0, "gene_names": "FBP26;FBP26;J0575", "protein_name": "Fructose-2,6-bisphosphatase", "disease": [ { "disease_id": "DOID:2018", "name": "hyperinsulinism", "description": "", "url": "https://disease-ontology.org/term/DOID:2018", "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ], "weight": 0.0 }, { "disease_id": "DOID:3978", "name": "extrinsic cardiomyopathy", "description": "A cardiomyopathy that is characterized by the pathology occurring outside of the myocardium.", "url": "https://disease-ontology.org/term/DOID:3978", "evidence": [ { "id": "3978", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3978" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "fructose-2,6-bisphosphate 2-phosphatase activity", "id": "GO:0004331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004331", "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" } ], "pmid": "" }, { "name": "6-phosphofructo-2-kinase activity", "id": "GO:0003873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003873", "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" } ], "pmid": "" } ], "biological_process": [ { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" } ], "pmid": "" }, { "name": "fructose metabolic process", "id": "GO:0006000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006000", "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" } ], "pmid": "" }, { "name": "fructose 2,6-bisphosphate metabolic process", "id": "GO:0006003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006003", "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32604-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003691", "url": "https://www.yeastgenome.org/locus/S000003691" }, { "database": "iPTMnet", "id": "P32604", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32604" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32604-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Thr150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003691", "url": "https://www.yeastgenome.org/locus/S000003691" }, { "database": "iPTMnet", "id": "P32604", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32604" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32604-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32604", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32604" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003691", "url": "https://www.yeastgenome.org/locus/S000003691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32604-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Tyr154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003691", "url": "https://www.yeastgenome.org/locus/S000003691" }, { "database": "iPTMnet", "id": "P32604", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32604" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32604-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Ser248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003691", "url": "https://www.yeastgenome.org/locus/S000003691" }, { "database": "iPTMnet", "id": "P32604", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32604" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32604-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Thr426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32604", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32604" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32604-1", "start_pos": "433", "end_pos": "433", "site_lbl": "Ser433", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32604", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32604" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003691", "url": "https://www.yeastgenome.org/locus/S000003691" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32604-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Ser435", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32604", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32604" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003691", "url": "https://www.yeastgenome.org/locus/S000003691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32604-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Ser436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32604", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32604" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003691", "url": "https://www.yeastgenome.org/locus/S000003691" } ] } ] }, { "uniprot_canonical_ac": "P32604-1", "start_pos": "446", "end_pos": "446", "site_lbl": "Ser446", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32604", "url": "https://www.uniprot.org/uniprotkb/P32604" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32604", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32604" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003691", "url": "https://www.yeastgenome.org/locus/S000003691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32604-1" }, { "uniprot_canonical_ac": "P32605-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 298, "chemical_mass": 34378.0, "gene_names": "MUD1;MUD1;YBR0915", "protein_name": "U1 small nuclear ribonucleoprotein A", "disease": [], "cellular_component": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" } ], "pmid": "" } ], "molecular_function": [ { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32605-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000323", "url": "https://www.yeastgenome.org/locus/S000000323" }, { "database": "iPTMnet", "id": "P32605", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32605" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32605-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Val228", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "I", "comment": "Splicing defects; when associated with 230-F--T-232.", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" }, { "database": "PubMed", "id": "8849781", "url": "https://glygen.org/publication/PubMed/8849781" } ] } ] }, { "uniprot_canonical_ac": "P32605-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Tyr268", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Splicing defects; when associated with 262-D-I-263.", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" }, { "database": "PubMed", "id": "8849781", "url": "https://glygen.org/publication/PubMed/8849781" } ] } ] }, { "uniprot_canonical_ac": "P32605-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Gly295", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "Splicing defects; when associated with 291-A--K-293.", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" }, { "database": "PubMed", "id": "8849781", "url": "https://glygen.org/publication/PubMed/8849781" } ] } ] }, { "uniprot_canonical_ac": "P32605-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Leu4", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "I", "comment": "Sensitive in DMS protection of U1 snRNA; when associated with 6-I-N-7.", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" }, { "database": "PubMed", "id": "8849781", "url": "https://glygen.org/publication/PubMed/8849781" } ] } ] }, { "uniprot_canonical_ac": "P32605-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Leu63", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "I", "comment": "Sensitive in DMS protection of U1 snRNA; when associated with 65-D--L-67.", "evidence": [ { "database": "UniProtKB", "id": "P32605", "url": "https://www.uniprot.org/uniprotkb/P32605" }, { "database": "PubMed", "id": "8849781", "url": "https://glygen.org/publication/PubMed/8849781" } ] } ] } ], "record_id": "P32605-1" }, { "uniprot_canonical_ac": "P32607-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 177, "chemical_mass": 19016.0, "gene_names": "RTG1;RTG1", "protein_name": "Retrograde regulation protein 1", "disease": [], "biological_process": [ { "name": "cellular response to oleic acid", "id": "GO:0071400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071400", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" }, { "name": "peroxisome fission", "id": "GO:0016559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016559", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" }, { "name": "mitochondria-nucleus signaling pathway", "id": "GO:0031930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031930", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32607-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Ser163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ser164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Tyr47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Thr55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32607-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Thr60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32607", "url": "https://www.uniprot.org/uniprotkb/P32607" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32607", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32607" }, { "database": "PubMed", "id": "22956768", "url": "https://glygen.org/publication/PubMed/22956768" }, { "database": "SGD", "id": "S000005428", "url": "https://www.yeastgenome.org/locus/S000005428" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32607-1" }, { "uniprot_canonical_ac": "P32608-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32608", "url": "https://www.uniprot.org/uniprotkb/P32608" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 588, "chemical_mass": 65572.0, "gene_names": "RTG2;NRF588;RTG2", "protein_name": "Retrograde regulation protein 2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32608", "url": "https://www.uniprot.org/uniprotkb/P32608" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "P32608", "url": "https://www.uniprot.org/uniprotkb/P32608" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P32608", "url": "https://www.uniprot.org/uniprotkb/P32608" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32608", "url": "https://www.uniprot.org/uniprotkb/P32608" } ], "pmid": "" }, { "name": "protein localization to nucleus", "id": "GO:0034504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034504", "evidence": [ { "database": "UniProtKB", "id": "P32608", "url": "https://www.uniprot.org/uniprotkb/P32608" } ], "pmid": "" }, { "name": "mitochondria-nucleus signaling pathway", "id": "GO:0031930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031930", "evidence": [ { "database": "UniProtKB", "id": "P32608", "url": "https://www.uniprot.org/uniprotkb/P32608" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "P32608", "url": "https://www.uniprot.org/uniprotkb/P32608" } ], "pmid": "" }, { "name": "maintenance of DNA trinucleotide repeats", "id": "GO:0035753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035753", "evidence": [ { "database": "UniProtKB", "id": "P32608", "url": "https://www.uniprot.org/uniprotkb/P32608" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphoprotein binding", "id": "GO:0051219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051219", "evidence": [ { "database": "UniProtKB", "id": "P32608", "url": "https://www.uniprot.org/uniprotkb/P32608" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32608-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Thr11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003221", "url": "https://www.yeastgenome.org/locus/S000003221" }, { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32608-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003221", "url": "https://www.yeastgenome.org/locus/S000003221" }, { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32608-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003221", "url": "https://www.yeastgenome.org/locus/S000003221" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32608-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Thr3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32608-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Ser515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003221", "url": "https://www.yeastgenome.org/locus/S000003221" }, { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32608-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Thr526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003221", "url": "https://www.yeastgenome.org/locus/S000003221" }, { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32608-1", "start_pos": "527", "end_pos": "527", "site_lbl": "Thr527", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003221", "url": "https://www.yeastgenome.org/locus/S000003221" }, { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32608-1", "start_pos": "533", "end_pos": "533", "site_lbl": "Ser533", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003221", "url": "https://www.yeastgenome.org/locus/S000003221" }, { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32608-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003221", "url": "https://www.yeastgenome.org/locus/S000003221" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32608-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003221", "url": "https://www.yeastgenome.org/locus/S000003221" }, { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32608-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Thr9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003221", "url": "https://www.yeastgenome.org/locus/S000003221" }, { "database": "iPTMnet", "id": "P32608", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32608" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32608-1" }, { "uniprot_canonical_ac": "P32609-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 515, "chemical_mass": 59443.0, "gene_names": "PEP7;PEP7;VAC1;VPL21;VPS19;VPT19", "protein_name": "Vacuolar segregation protein PEP7", "disease": [ { "disease_id": "DOID:0061158", "name": "Kariminejad neurodevelopmental syndrome", "description": "An autosomal recessive intellectual developmental disorder characterized by global developmental delay with delayed walking by a few years, speech delay, and impaired intellectual development that has_material_basis_in homozygous mutation in the RBSN gene on chromosome 3p25.", "url": "https://disease-ontology.org/term/DOID:0061158", "evidence": [ { "id": "0061158", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061158" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" }, { "name": "cytoplasmic side of endosome membrane", "id": "GO:0010009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010009", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" } ], "biological_process": [ { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" }, { "name": "vacuole inheritance", "id": "GO:0000011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000011", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "P32609", "url": "https://www.uniprot.org/uniprotkb/P32609" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32609-1" }, { "uniprot_canonical_ac": "P32610-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 256, "chemical_mass": 29194.0, "gene_names": "VMA8;SYGP-ORF11;VMA8", "protein_name": "V-type proton ATPase subunit D", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase complex", "id": "GO:0016471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016471", "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V1 domain", "id": "GO:0000221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000221", "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "pmid": "" } ], "biological_process": [ { "name": "endosomal lumen acidification", "id": "GO:0048388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048388", "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "pmid": "" }, { "name": "Golgi lumen acidification", "id": "GO:0061795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061795", "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "pmid": "" } ], "molecular_function": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "P32610", "url": "https://www.uniprot.org/uniprotkb/P32610" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32610-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000777", "url": "https://www.yeastgenome.org/locus/S000000777" }, { "database": "iPTMnet", "id": "P32610", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32610" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32610-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000777", "url": "https://www.yeastgenome.org/locus/S000000777" }, { "database": "iPTMnet", "id": "P32610", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32610" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32610-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000777", "url": "https://www.yeastgenome.org/locus/S000000777" }, { "database": "iPTMnet", "id": "P32610", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32610" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32610-1" }, { "uniprot_canonical_ac": "P32614-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32614", "url": "https://www.uniprot.org/uniprotkb/P32614" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 470, "chemical_mass": 50844.0, "gene_names": "FRD1;FRD1;FRDS1;FRDS;SYGP-ORF35", "protein_name": "Fumarate reductase 1", "disease": [], "biological_process": [ { "name": "cellular response to anoxia", "id": "GO:0071454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071454", "evidence": [ { "database": "UniProtKB", "id": "P32614", "url": "https://www.uniprot.org/uniprotkb/P32614" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32614", "url": "https://www.uniprot.org/uniprotkb/P32614" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32614", "url": "https://www.uniprot.org/uniprotkb/P32614" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32614", "url": "https://www.uniprot.org/uniprotkb/P32614" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32614", "url": "https://www.uniprot.org/uniprotkb/P32614" } ], "pmid": "" } ], "molecular_function": [ { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "P32614", "url": "https://www.uniprot.org/uniprotkb/P32614" } ], "pmid": "" }, { "name": "fumarate reductase (NADH) activity", "id": "GO:0016156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016156", "evidence": [ { "database": "UniProtKB", "id": "P32614", "url": "https://www.uniprot.org/uniprotkb/P32614" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32614-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000773", "url": "https://www.yeastgenome.org/locus/S000000773" }, { "database": "iPTMnet", "id": "P32614", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32614" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32614-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Ser270", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000773", "url": "https://www.yeastgenome.org/locus/S000000773" }, { "database": "iPTMnet", "id": "P32614", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32614" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32614-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000773", "url": "https://www.yeastgenome.org/locus/S000000773" }, { "database": "iPTMnet", "id": "P32614", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32614" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32614-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000773", "url": "https://www.yeastgenome.org/locus/S000000773" }, { "database": "iPTMnet", "id": "P32614", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32614" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32614-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32614", "url": "https://www.uniprot.org/uniprotkb/P32614" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32614", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32614" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000773", "url": "https://www.yeastgenome.org/locus/S000000773" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32614-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000773", "url": "https://www.yeastgenome.org/locus/S000000773" }, { "database": "iPTMnet", "id": "P32614", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32614" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32614-1" }, { "uniprot_canonical_ac": "P32621-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32621", "url": "https://www.uniprot.org/uniprotkb/P32621" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 518, "chemical_mass": 56822.0, "gene_names": "GDA1;GDA1;SYGP-ORF16", "protein_name": "Guanosine-diphosphatase", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P32621", "url": "https://www.uniprot.org/uniprotkb/P32621" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P32621", "url": "https://www.uniprot.org/uniprotkb/P32621" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P32621", "url": "https://www.uniprot.org/uniprotkb/P32621" } ], "pmid": "" } ], "biological_process": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "P32621", "url": "https://www.uniprot.org/uniprotkb/P32621" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "P32621", "url": "https://www.uniprot.org/uniprotkb/P32621" } ], "pmid": "" }, { "name": "nucleoside diphosphate catabolic process", "id": "GO:0009134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009134", "evidence": [ { "database": "UniProtKB", "id": "P32621", "url": "https://www.uniprot.org/uniprotkb/P32621" } ], "pmid": "" } ], "molecular_function": [ { "name": "GDP phosphatase activity", "id": "GO:0004382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004382", "evidence": [ { "database": "UniProtKB", "id": "P32621", "url": "https://www.uniprot.org/uniprotkb/P32621" } ], "pmid": "" }, { "name": "UDP phosphatase activity", "id": "GO:0045134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045134", "evidence": [ { "database": "UniProtKB", "id": "P32621", "url": "https://www.uniprot.org/uniprotkb/P32621" } ], "pmid": "" }, { "name": "ribonucleoside triphosphate phosphatase activity", "id": "GO:0017111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017111", "evidence": [ { "database": "UniProtKB", "id": "P32621", "url": "https://www.uniprot.org/uniprotkb/P32621" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32621-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Asn280", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 280, "start_aa": "Asn", "end_pos": 280, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn280", "evidence": [ { "id": "P32621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32621#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32621-1", "start_pos": "335", "end_pos": "335", "site_lbl": "Asn335", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 335, "start_aa": "Asn", "end_pos": 335, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn335", "evidence": [ { "id": "P32621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32621#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32621-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Asn41", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 41, "start_aa": "Asn", "end_pos": 41, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn41", "evidence": [ { "id": "P32621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32621#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32621-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Thr37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32621", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32621" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P32621-1" }, { "uniprot_canonical_ac": "P32623-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32623", "url": "https://www.uniprot.org/uniprotkb/P32623" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 467, "chemical_mass": 49906.0, "gene_names": "UTR2;CHR2;CRH2;SYGP-ORF18;UTR2", "protein_name": "Congo red hypersensitive protein 2", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P32623", "url": "https://www.uniprot.org/uniprotkb/P32623" } ], "pmid": "" }, { "name": "cellular bud neck septin ring", "id": "GO:0000144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000144", "evidence": [ { "database": "UniProtKB", "id": "P32623", "url": "https://www.uniprot.org/uniprotkb/P32623" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P32623", "url": "https://www.uniprot.org/uniprotkb/P32623" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P32623", "url": "https://www.uniprot.org/uniprotkb/P32623" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "P32623", "url": "https://www.uniprot.org/uniprotkb/P32623" } ], "pmid": "" }, { "name": "chitin metabolic process", "id": "GO:0006030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006030", "evidence": [ { "database": "UniProtKB", "id": "P32623", "url": "https://www.uniprot.org/uniprotkb/P32623" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P32623", "url": "https://www.uniprot.org/uniprotkb/P32623" } ], "pmid": "" } ], "molecular_function": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "P32623", "url": "https://www.uniprot.org/uniprotkb/P32623" } ], "pmid": "" }, { "name": "endochitinase activity", "id": "GO:0008843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008843", "evidence": [ { "database": "UniProtKB", "id": "P32623", "url": "https://www.uniprot.org/uniprotkb/P32623" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32623-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Asn190", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 190, "start_aa": "Asn", "end_pos": 190, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn190", "evidence": [ { "id": "P32623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32623#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Asn196", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 196, "start_aa": "Asn", "end_pos": 196, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn196", "evidence": [ { "id": "P32623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32623#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Asn233", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 233, "start_aa": "Asn", "end_pos": 233, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn233", "evidence": [ { "id": "P32623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32623#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Asn237", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 237, "start_aa": "Asn", "end_pos": 237, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn237", "evidence": [ { "id": "P32623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32623#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Asn261", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 261, "start_aa": "Asn", "end_pos": 261, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn261", "evidence": [ { "id": "P32623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32623#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Asn28", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 28, "start_aa": "Asn", "end_pos": 28, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn28", "evidence": [ { "id": "P32623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32623#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Asn297", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 297, "start_aa": "Asn", "end_pos": 297, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn297", "evidence": [ { "id": "P32623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32623#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Asn310", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 310, "start_aa": "Asn", "end_pos": 310, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn310", "evidence": [ { "id": "P32623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32623#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Asn96", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 96, "start_aa": "Asn", "end_pos": 96, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn96", "evidence": [ { "id": "P32623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32623#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000766", "url": "https://www.yeastgenome.org/locus/S000000766" }, { "database": "iPTMnet", "id": "P32623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32623" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Ser132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000766", "url": "https://www.yeastgenome.org/locus/S000000766" }, { "database": "iPTMnet", "id": "P32623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32623" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32623-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000766", "url": "https://www.yeastgenome.org/locus/S000000766" }, { "database": "iPTMnet", "id": "P32623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32623" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32623-1" }, { "uniprot_canonical_ac": "P32626-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32626", "url": "https://www.uniprot.org/uniprotkb/P32626" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 227, "chemical_mass": 25187.0, "gene_names": "UTR4;SYGP-ORF20;UTR4", "protein_name": "Enolase-phosphatase E1", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P32626", "url": "https://www.uniprot.org/uniprotkb/P32626" } ], "pmid": "" }, { "name": "acireductone synthase activity", "id": "GO:0043874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043874", "evidence": [ { "database": "UniProtKB", "id": "P32626", "url": "https://www.uniprot.org/uniprotkb/P32626" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32626", "url": "https://www.uniprot.org/uniprotkb/P32626" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32626", "url": "https://www.uniprot.org/uniprotkb/P32626" } ], "pmid": "" } ], "biological_process": [ { "name": "L-methionine salvage from methylthioadenosine", "id": "GO:0019509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019509", "evidence": [ { "database": "UniProtKB", "id": "P32626", "url": "https://www.uniprot.org/uniprotkb/P32626" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32626-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000764", "url": "https://www.yeastgenome.org/locus/S000000764" }, { "database": "iPTMnet", "id": "P32626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32626" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32626-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000764", "url": "https://www.yeastgenome.org/locus/S000000764" }, { "database": "iPTMnet", "id": "P32626", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32626" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32626-1" }, { "uniprot_canonical_ac": "P32629-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32629", "url": "https://www.uniprot.org/uniprotkb/P32629" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 500, "chemical_mass": 58182.0, "gene_names": "ANP1;ANP1;GEM3;MNN8;SYGP-ORF28", "protein_name": "Mannan polymerase II complex ANP1 subunit", "disease": [], "biological_process": [ { "name": "cell wall mannoprotein biosynthetic process", "id": "GO:0000032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000032", "evidence": [ { "database": "UniProtKB", "id": "P32629", "url": "https://www.uniprot.org/uniprotkb/P32629" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "P32629", "url": "https://www.uniprot.org/uniprotkb/P32629" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32629", "url": "https://www.uniprot.org/uniprotkb/P32629" } ], "pmid": "" }, { "name": "Golgi cis cisterna", "id": "GO:0000137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000137", "evidence": [ { "database": "UniProtKB", "id": "P32629", "url": "https://www.uniprot.org/uniprotkb/P32629" } ], "pmid": "" }, { "name": "mannan polymerase complex", "id": "GO:0000136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000136", "evidence": [ { "database": "UniProtKB", "id": "P32629", "url": "https://www.uniprot.org/uniprotkb/P32629" } ], "pmid": "" } ], "molecular_function": [ { "name": "alpha-1,6-mannosyltransferase activity", "id": "GO:0000009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000009", "evidence": [ { "database": "UniProtKB", "id": "P32629", "url": "https://www.uniprot.org/uniprotkb/P32629" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32629-1" }, { "uniprot_canonical_ac": "P32639-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 2163, "chemical_mass": 246185.0, "gene_names": "BRR2;BRR2;PRP44;RSS1;SLT22;SNU246;SYGP-ORF66", "protein_name": "Pre-mRNA-splicing helicase BRR2", "disease": [ { "disease_id": "DOID:0110366", "name": "retinitis pigmentosa 33", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the SNRNP200 gene on chromosome 2q11.", "url": "https://disease-ontology.org/term/DOID:0110366", "evidence": [ { "id": "0110366", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110366" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" }, { "name": "spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)", "id": "GO:0000388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000388", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32639-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Ser101", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" }, { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Tyr19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" }, { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" }, { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" }, { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Ser403", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Ser410", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" }, { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Thr416", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" }, { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Ser419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" }, { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Ser553", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" }, { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "649", "end_pos": "649", "site_lbl": "Ser649", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" }, { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "955", "end_pos": "955", "site_lbl": "Tyr955", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "961", "end_pos": "961", "site_lbl": "Ser961", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "962", "end_pos": "962", "site_lbl": "Ser962", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32639", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32639" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000974", "url": "https://www.yeastgenome.org/locus/S000000974" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "1107", "end_pos": "1107", "site_lbl": "Arg1107", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduced ATP-dependent RNA helicase activity.", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" }, { "database": "PubMed", "id": "19525970", "url": "https://glygen.org/publication/PubMed/19525970" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "1110", "end_pos": "1110", "site_lbl": "Arg1110", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "N", "comment": "Abolishes unwinding of U4/U6 snRNA.", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" }, { "database": "PubMed", "id": "19716790", "url": "https://glygen.org/publication/PubMed/19716790" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "858", "end_pos": "858", "site_lbl": "Gly858", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "Reduces spliceosomal pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" }, { "database": "PubMed", "id": "23124065", "url": "https://glygen.org/publication/PubMed/23124065" } ] } ] }, { "uniprot_canonical_ac": "P32639-1", "start_pos": "938", "end_pos": "938", "site_lbl": "Trp938", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "Q", "comment": "Strongly reduced unwinding of U4/U6 snRNA.", "evidence": [ { "database": "UniProtKB", "id": "P32639", "url": "https://www.uniprot.org/uniprotkb/P32639" }, { "database": "PubMed", "id": "19716790", "url": "https://glygen.org/publication/PubMed/19716790" } ] } ] } ], "record_id": "P32639-1" }, { "uniprot_canonical_ac": "P32641-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 659, "chemical_mass": 75727.0, "gene_names": "RAD24;RAD24;SYGP-ORF60", "protein_name": "Checkpoint protein RAD24", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "DNA clamp loader activity", "id": "GO:0003689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003689", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "Rad17 RFC-like complex", "id": "GO:0031389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031389", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "chromosome, telomeric repeat region", "id": "GO:0140445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140445", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "mitotic intra-S DNA damage checkpoint signaling", "id": "GO:0031573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031573", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32641-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32641", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32641" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000975", "url": "https://www.yeastgenome.org/locus/S000000975" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32641-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Thr32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000975", "url": "https://www.yeastgenome.org/locus/S000000975" }, { "database": "iPTMnet", "id": "P32641", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32641" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32641-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000975", "url": "https://www.yeastgenome.org/locus/S000000975" }, { "database": "iPTMnet", "id": "P32641", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32641" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32641-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000975", "url": "https://www.yeastgenome.org/locus/S000000975" }, { "database": "iPTMnet", "id": "P32641", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32641" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32641-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Thr41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000975", "url": "https://www.yeastgenome.org/locus/S000000975" }, { "database": "iPTMnet", "id": "P32641", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32641" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32641-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Ser626", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000975", "url": "https://www.yeastgenome.org/locus/S000000975" }, { "database": "iPTMnet", "id": "P32641", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32641" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32641-1", "start_pos": "637", "end_pos": "637", "site_lbl": "Ser637", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32641", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32641" }, { "database": "PubMed", "id": "25719602", "url": "https://glygen.org/publication/PubMed/25719602" } ] } ] }, { "uniprot_canonical_ac": "P32641-1", "start_pos": "650", "end_pos": "650", "site_lbl": "Ser650", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32641", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32641" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000975", "url": "https://www.yeastgenome.org/locus/S000000975" } ] } ] }, { "uniprot_canonical_ac": "P32641-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Ser652", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32641", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32641" }, { "database": "SGD", "id": "S000000975", "url": "https://www.yeastgenome.org/locus/S000000975" } ] } ] }, { "uniprot_canonical_ac": "P32641-1", "start_pos": "654", "end_pos": "654", "site_lbl": "Ser654", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32641", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32641" }, { "database": "SGD", "id": "S000000975", "url": "https://www.yeastgenome.org/locus/S000000975" } ] } ] }, { "uniprot_canonical_ac": "P32641-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Lys115", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "Reduces NTP-binding and hydrolysis. Shows DNA damage sensitivity.", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" }, { "database": "PubMed", "id": "10913172", "url": "https://glygen.org/publication/PubMed/10913172" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "No effect on NTP-binding and hydrolysis. Resistant to DNA damage.", "evidence": [ { "database": "UniProtKB", "id": "P32641", "url": "https://www.uniprot.org/uniprotkb/P32641" }, { "database": "PubMed", "id": "10913172", "url": "https://glygen.org/publication/PubMed/10913172" } ] } ] } ], "record_id": "P32641-1" }, { "uniprot_canonical_ac": "P32643-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32643", "url": "https://www.uniprot.org/uniprotkb/P32643" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 299, "chemical_mass": 34768.0, "gene_names": "TMT1;SYGP-ORF63;TAM1;TMT1", "protein_name": "Trans-aconitate 3-methyltransferase", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32643", "url": "https://www.uniprot.org/uniprotkb/P32643" } ], "pmid": "" } ], "biological_process": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "P32643", "url": "https://www.uniprot.org/uniprotkb/P32643" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "P32643", "url": "https://www.uniprot.org/uniprotkb/P32643" } ], "pmid": "" } ], "molecular_function": [ { "name": "trans-aconitate 3-methyltransferase activity", "id": "GO:0046547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046547", "evidence": [ { "database": "UniProtKB", "id": "P32643", "url": "https://www.uniprot.org/uniprotkb/P32643" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32643-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Tyr14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32643" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000977", "url": "https://www.yeastgenome.org/locus/S000000977" } ] } ] }, { "uniprot_canonical_ac": "P32643-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000977", "url": "https://www.yeastgenome.org/locus/S000000977" }, { "database": "iPTMnet", "id": "P32643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32643" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32643-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000977", "url": "https://www.yeastgenome.org/locus/S000000977" }, { "database": "iPTMnet", "id": "P32643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32643" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32643-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000977", "url": "https://www.yeastgenome.org/locus/S000000977" }, { "database": "iPTMnet", "id": "P32643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32643" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P32643-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000977", "url": "https://www.yeastgenome.org/locus/S000000977" }, { "database": "iPTMnet", "id": "P32643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32643" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32643-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000977", "url": "https://www.yeastgenome.org/locus/S000000977" }, { "database": "iPTMnet", "id": "P32643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32643" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32643-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32643" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000977", "url": "https://www.yeastgenome.org/locus/S000000977" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32643-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Thr87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000977", "url": "https://www.yeastgenome.org/locus/S000000977" }, { "database": "iPTMnet", "id": "P32643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32643" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32643-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Ser97", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000977", "url": "https://www.yeastgenome.org/locus/S000000977" }, { "database": "iPTMnet", "id": "P32643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32643" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32643-1" }, { "uniprot_canonical_ac": "P32657-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1468, "chemical_mass": 168241.0, "gene_names": "CHD1;CHD1;SYGP-ORF4", "protein_name": "ATP-dependent chromatin remodeler CHD1", "disease": [ { "disease_id": "DOID:0050834", "name": "CHARGE syndrome", "description": "A syndrome that is characterized by a pattern of congenital anomalies including choanal atresia and malformations of the heart, inner ear, and retina.", "url": "https://disease-ontology.org/term/DOID:0050834", "evidence": [ { "id": "0050834", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050834" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060475", "name": "myoclonic-atonic epilepsy", "description": "An idiopathic generalized epilepsy characterized by onset of multiple seizure types in the first few years of life and associated with poor prognosis. Affected individuals have cognitive regression and intellectual disability and that has_material_basis_in heterozygous mutation in the SLC6A1 gene on chromosome 3p25.", "url": "https://disease-ontology.org/term/DOID:0060475", "evidence": [ { "id": "0060475", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060475" } ], "weight": 0.0 }, { "disease_id": "DOID:0080909", "name": "castration-resistant prostate carcinoma", "description": "A prostate carcinoma that is characterized by continued growth and spread despite the surgical removal of the testes or medical intervention to block androgen production.", "url": "https://disease-ontology.org/term/DOID:0080909", "evidence": [ { "id": "0080909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080909" } ], "weight": 0.0 }, { "disease_id": "DOID:0081325", "name": "developmental and epileptic encephalopathy 94", "description": "A developmental and epileptic encephalopathy characterized by onset of multiple seizure types in the first few years of life and associated with poor prognosis and that has_material_basis_in heterozygous mutation in the CHD2 gene on chromosome 15q26.", "url": "https://disease-ontology.org/term/DOID:0081325", "evidence": [ { "id": "0081325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081325" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of DNA-templated DNA replication", "id": "GO:2000104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000104", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "nucleosome organization", "id": "GO:0034728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034728", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "DNA double-strand break processing", "id": "GO:0000729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000729", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "sister chromatid cohesion", "id": "GO:0007062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007062", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "termination of RNA polymerase I transcription", "id": "GO:0006363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006363", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription", "id": "GO:0006369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006369", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": "GO:1902275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902275", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "regulation of transcriptional start site selection at RNA polymerase II promoter", "id": "GO:0001178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001178", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "rDNA binding", "id": "GO:0000182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000182", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "nucleosome array spacer activity", "id": "GO:0140750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140750", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "histone H3K4me3 reader activity", "id": "GO:0140002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140002", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "SLIK (SAGA-like) complex", "id": "GO:0046695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046695", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" }, { "name": "nucleolar chromatin", "id": "GO:0030874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030874", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32657-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 119, "start_aa": "Ser", "end_pos": 119, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser119", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32657", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32657" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Thr120", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 120, "start_aa": "Thr", "end_pos": 120, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr120", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32657", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32657" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1232", "end_pos": "1232", "site_lbl": "Thr1232", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1232, "start_aa": "Thr", "end_pos": 1232, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1232", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Thr125", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 125, "start_aa": "Thr", "end_pos": 125, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr125", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32657", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32657" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1341", "end_pos": "1341", "site_lbl": "Thr1341", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1341, "start_aa": "Thr", "end_pos": 1341, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1341", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1009", "end_pos": "1009", "site_lbl": "Ser1009", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1164", "end_pos": "1164", "site_lbl": "Thr1164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1225", "end_pos": "1225", "site_lbl": "Ser1225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1226", "end_pos": "1226", "site_lbl": "Ser1226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1227", "end_pos": "1227", "site_lbl": "Ser1227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1229", "end_pos": "1229", "site_lbl": "Thr1229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1230", "end_pos": "1230", "site_lbl": "Thr1230", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1270", "end_pos": "1270", "site_lbl": "Thr1270", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1272", "end_pos": "1272", "site_lbl": "Ser1272", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1274", "end_pos": "1274", "site_lbl": "Ser1274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1300", "end_pos": "1300", "site_lbl": "Ser1300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1302", "end_pos": "1302", "site_lbl": "Thr1302", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1306", "end_pos": "1306", "site_lbl": "Thr1306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1316", "end_pos": "1316", "site_lbl": "Ser1316", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1333", "end_pos": "1333", "site_lbl": "Thr1333", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1336", "end_pos": "1336", "site_lbl": "Ser1336", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1339", "end_pos": "1339", "site_lbl": "Ser1339", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1358", "end_pos": "1358", "site_lbl": "Ser1358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1361", "end_pos": "1361", "site_lbl": "Ser1361", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1362", "end_pos": "1362", "site_lbl": "Ser1362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1364", "end_pos": "1364", "site_lbl": "Ser1364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1370", "end_pos": "1370", "site_lbl": "Tyr1370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1372", "end_pos": "1372", "site_lbl": "Ser1372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1421", "end_pos": "1421", "site_lbl": "Ser1421", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "1430", "end_pos": "1430", "site_lbl": "Ser1430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Thr325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Tyr32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "824", "end_pos": "824", "site_lbl": "Thr824", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "866", "end_pos": "866", "site_lbl": "Ser866", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Thr8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "904", "end_pos": "904", "site_lbl": "Thr904", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "977", "end_pos": "977", "site_lbl": "Ser977", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "983", "end_pos": "983", "site_lbl": "Thr983", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "987", "end_pos": "987", "site_lbl": "Ser987", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "989", "end_pos": "989", "site_lbl": "Ser989", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "993", "end_pos": "993", "site_lbl": "Ser993", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "995", "end_pos": "995", "site_lbl": "Ser995", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000966", "url": "https://www.yeastgenome.org/locus/S000000966" }, { "database": "iPTMnet", "id": "P32657", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32657" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Glu220", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "L", "comment": "No interaction with methylated histone H3 'K-4'.", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "15647753", "url": "https://glygen.org/publication/PubMed/15647753" }, { "database": "PubMed", "id": "17433364", "url": "https://glygen.org/publication/PubMed/17433364" } ] }, { "sequence_org": "E", "sequence_mut": "W", "comment": "No interaction with methylated histone H3 'K-4'.", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "15647753", "url": "https://glygen.org/publication/PubMed/15647753" }, { "database": "PubMed", "id": "17433364", "url": "https://glygen.org/publication/PubMed/17433364" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "222", "end_pos": "222", "site_lbl": "His222", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "Confers interaction with methylated histone H3 'K-4'.", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "15647753", "url": "https://glygen.org/publication/PubMed/15647753" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Leu314", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "Y", "comment": "No effect on interaction with methylated histone H3 'K-4'.", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "15647753", "url": "https://glygen.org/publication/PubMed/15647753" } ] } ] }, { "uniprot_canonical_ac": "P32657-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Tyr316", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "E", "comment": "Disrupts interaction with methylated histone H3 'K-4'; abrogates histone acetylation activity of SLIK.", "evidence": [ { "database": "UniProtKB", "id": "P32657", "url": "https://www.uniprot.org/uniprotkb/P32657" }, { "database": "PubMed", "id": "15647753", "url": "https://glygen.org/publication/PubMed/15647753" } ] } ] } ], "record_id": "P32657-1" }, { "uniprot_canonical_ac": "P32660-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1571, "chemical_mass": 177798.0, "gene_names": "DNF1;DNF1;SYGP-ORF7", "protein_name": "Phospholipid-transporting ATPase DNF1", "disease": [ { "disease_id": "DOID:0070226", "name": "progressive familial intrahepatic cholestasis 1", "description": "A progressive familial intrahepatic cholestasis characterized by autosomal recessive inheritance that has_material_basis_in mutation in the ATP8B1 gene on chromosome 18q21.", "url": "https://disease-ontology.org/term/DOID:0070226", "evidence": [ { "id": "0070226", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070226" } ], "weight": 0.0 }, { "disease_id": "DOID:0070228", "name": "intrahepatic cholestasis of pregnancy 1", "description": "An intrahepatic cholestasis of pregnancy characterized by autosomal dominant inheritance that has_material_basis_in mutation in the ATP8B1 gene on chromosome 18q21.", "url": "https://disease-ontology.org/term/DOID:0070228", "evidence": [ { "id": "0070228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070228" } ], "weight": 0.0 }, { "disease_id": "DOID:0070231", "name": "benign recurrent intrahepatic cholestasis 1", "description": "A benign recurrent intrahepatic cholestasis characterized by typically autosomal recessive inheritance that has_material_basis_in mutation in the ATP8B1 gene on chromosome 18q.", "url": "https://disease-ontology.org/term/DOID:0070231", "evidence": [ { "id": "0070231", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070231" } ], "weight": 0.0 }, { "disease_id": "DOID:1852", "name": "intrahepatic cholestasis", "description": "A cholestasis characterized by impairment of the bile flow caused by obstruction located_in liver.", "url": "https://disease-ontology.org/term/DOID:1852", "evidence": [ { "id": "1852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1852" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "phosphatidylethanolamine flippase activity", "id": "GO:0090555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090555", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "phosphatidylcholine floppase activity", "id": "GO:0090554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090554", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "phosphatidylserine floppase activity", "id": "GO:0090556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090556", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "ATPase-coupled intramembrane lipid transporter activity", "id": "GO:0140326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140326", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "phosphatidylcholine flippase activity", "id": "GO:0140345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140345", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "phosphatidylserine flippase activity", "id": "GO:0140346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140346", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "glycosylceramide flippase activity", "id": "GO:0140351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140351", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "phospholipid-translocating ATPase complex", "id": "GO:1990531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990531", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "cell septum", "id": "GO:0030428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030428", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "mating projection tip membrane", "id": "GO:0070867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070867", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" }, { "name": "ceramide translocation", "id": "GO:0099040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099040", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32660-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Thr109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1460", "end_pos": "1460", "site_lbl": "Ser1460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1463", "end_pos": "1463", "site_lbl": "Ser1463", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1466", "end_pos": "1466", "site_lbl": "Ser1466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1483", "end_pos": "1483", "site_lbl": "Ser1483", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1495", "end_pos": "1495", "site_lbl": "Thr1495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1496", "end_pos": "1496", "site_lbl": "Ser1496", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1500", "end_pos": "1500", "site_lbl": "Thr1500", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1506", "end_pos": "1506", "site_lbl": "Ser1506", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1520", "end_pos": "1520", "site_lbl": "Ser1520", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1526", "end_pos": "1526", "site_lbl": "Ser1526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "19966303", "url": "https://glygen.org/publication/PubMed/19966303" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Thr152", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1544", "end_pos": "1544", "site_lbl": "Tyr1544", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1545", "end_pos": "1545", "site_lbl": "Ser1545", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1551", "end_pos": "1551", "site_lbl": "Thr1551", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1552", "end_pos": "1552", "site_lbl": "Ser1552", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19966303", "url": "https://glygen.org/publication/PubMed/19966303" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1559", "end_pos": "1559", "site_lbl": "Thr1559", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1563", "end_pos": "1563", "site_lbl": "Ser1563", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Ser343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Ser347", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Ser348", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Ser351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Ser358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Tyr361", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Tyr368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Tyr77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Ser81", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Thr85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "92", "end_pos": "92", "site_lbl": "Ser92", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Thr94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32660", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32660" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000968", "url": "https://www.yeastgenome.org/locus/S000000968" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1194", "end_pos": "1194", "site_lbl": "Lys1194", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Decreases phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1226", "end_pos": "1226", "site_lbl": "Asn1226", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Decreases glucosylceramide, phosphatidylethanolamine, and phosphatidylcholine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "33320091", "url": "https://glygen.org/publication/PubMed/33320091" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "1235", "end_pos": "1235", "site_lbl": "Ile1235", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "F", "comment": "Increases phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine and sphingomyelin uptake, but not phosphatidic acid uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Ser243", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "Y", "comment": "Increases phosphatidylcholine and phosphatidylserine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "31786280", "url": "https://glygen.org/publication/PubMed/31786280" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Arg264", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Increases glucosylceramide, phosphatidylethanolamine, and phosphatidylcholine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "33320091", "url": "https://glygen.org/publication/PubMed/33320091" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "545", "end_pos": "545", "site_lbl": "Ile545", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "T", "comment": "Decreases phosphatidylcholine and phosphatidylehtanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "550", "end_pos": "550", "site_lbl": "Asn550", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "I", "comment": "Increases phosphatidylserine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "30824614", "url": "https://glygen.org/publication/PubMed/30824614" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "N", "sequence_mut": "K", "comment": "Does not alter phosphatidic acid or sphingomyelin uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "30824614", "url": "https://glygen.org/publication/PubMed/30824614" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "N", "sequence_mut": "K", "comment": "Increases phosphatidylserine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "30824614", "url": "https://glygen.org/publication/PubMed/30824614" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "N", "sequence_mut": "S", "comment": "Does not alter phosphatidic acid or sphingomyelin uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "30824614", "url": "https://glygen.org/publication/PubMed/30824614" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "N", "sequence_mut": "S", "comment": "Increases phosphatidylserine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "30824614", "url": "https://glygen.org/publication/PubMed/30824614" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "N", "sequence_mut": "Y", "comment": "Increases phosphatidylserine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "30824614", "url": "https://glygen.org/publication/PubMed/30824614" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Phe551", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "L", "comment": "Decreases phosphatidylcholine and phosphatidylehtanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "555", "end_pos": "555", "site_lbl": "Ile555", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "L", "comment": "Decreases phosphatidylcholine and phosphatidylehtanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "558", "end_pos": "558", "site_lbl": "Val558", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "E", "comment": "Decreases phosphatidylcholine and phosphatidylehtanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "565", "end_pos": "565", "site_lbl": "Phe565", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "L", "comment": "Decreases phosphatidylcholine and phosphatidylehtanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "568", "end_pos": "568", "site_lbl": "Gly568", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "571", "end_pos": "571", "site_lbl": "Asn571", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "574", "end_pos": "574", "site_lbl": "Tyr574", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Tyr575", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "Y", "sequence_mut": "N", "comment": "Decreases phosphatidylcholine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "Y", "sequence_mut": "S", "comment": "Decreases phosphatidylcholine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "578", "end_pos": "578", "site_lbl": "Lys578", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "K", "sequence_mut": "E", "comment": "Increases phosphatidylserine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Glu586", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "587", "end_pos": "587", "site_lbl": "Phe587", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "F", "sequence_mut": "L", "comment": "Decreases phosphatidylcholine uptake, but not phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "22308393", "url": "https://glygen.org/publication/PubMed/22308393" } ] }, { "sequence_org": "F", "sequence_mut": "Y", "comment": "Decreases phosphatidylcholine uptake, but not phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "22308393", "url": "https://glygen.org/publication/PubMed/22308393" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "588", "end_pos": "588", "site_lbl": "Gly588", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine and phosphatidylserine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Val604", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "606", "end_pos": "606", "site_lbl": "Val606", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Gln610", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Decreases glucosylceramide and phosphatidylethanolamine uptake, but not phosphatidylcholine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "33320091", "url": "https://glygen.org/publication/PubMed/33320091" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "611", "end_pos": "611", "site_lbl": "Ser611", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Increases glucosylceramide, phosphatidylethanolamine, and phosphatidylcholine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "33320091", "url": "https://glygen.org/publication/PubMed/33320091" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "618", "end_pos": "618", "site_lbl": "Tyr618", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "C", "comment": "Decreases phosphatidylcholine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] }, { "sequence_org": "Y", "sequence_mut": "F", "comment": "Increases phosphatidylserine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "22308393", "url": "https://glygen.org/publication/PubMed/22308393" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Val621", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Decreases phosphatidylcholine and phosphatidylethanolamine uptake, and increases phosphatidylserine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "622", "end_pos": "622", "site_lbl": "Glu622", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "V", "comment": "Decreases phosphatidylcholine and increases phosphatidylserine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "623", "end_pos": "623", "site_lbl": "Ile623", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "F", "comment": "Decreases phosphatidylcholine and phosphatidylethanolamine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "23302692", "url": "https://glygen.org/publication/PubMed/23302692" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Trp652", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Decreases glucosylceramide, phosphatidylethanolamine, and phosphatidylcholine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "33320091", "url": "https://glygen.org/publication/PubMed/33320091" } ] }, { "sequence_org": "W", "sequence_mut": "S", "comment": "Decreases glucosylceramide, phosphatidylethanolamine, and phosphatidylcholine uptake.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "33320091", "url": "https://glygen.org/publication/PubMed/33320091" } ] } ] }, { "uniprot_canonical_ac": "P32660-1", "start_pos": "667", "end_pos": "667", "site_lbl": "Asp667", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "Decreases interaction with LEM3.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19411703", "url": "https://glygen.org/publication/PubMed/19411703" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Decreases interaction with LEM3.", "evidence": [ { "database": "UniProtKB", "id": "P32660", "url": "https://www.uniprot.org/uniprotkb/P32660" }, { "database": "PubMed", "id": "19411703", "url": "https://glygen.org/publication/PubMed/19411703" } ] } ] } ], "record_id": "P32660-1" }, { "uniprot_canonical_ac": "P32768-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32768", "url": "https://www.uniprot.org/uniprotkb/P32768" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1537, "chemical_mass": 160668.0, "gene_names": "FLO1;FLO1;FLO2;FLO4;FLO8", "protein_name": "Flocculation protein FLO1", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32768", "url": "https://www.uniprot.org/uniprotkb/P32768" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32768", "url": "https://www.uniprot.org/uniprotkb/P32768" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P32768", "url": "https://www.uniprot.org/uniprotkb/P32768" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P32768", "url": "https://www.uniprot.org/uniprotkb/P32768" } ], "pmid": "" } ], "molecular_function": [ { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "P32768", "url": "https://www.uniprot.org/uniprotkb/P32768" } ], "pmid": "" } ], "biological_process": [ { "name": "flocculation", "id": "GO:0000128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000128", "evidence": [ { "database": "UniProtKB", "id": "P32768", "url": "https://www.uniprot.org/uniprotkb/P32768" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32768-1", "start_pos": "1114", "end_pos": "1114", "site_lbl": "Asn1114", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1114, "start_aa": "Asn", "end_pos": 1114, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1114", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Asn135", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 135, "start_aa": "Asn", "end_pos": 135, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn135", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Asn187", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 187, "start_aa": "Asn", "end_pos": 187, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn187", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Asn262", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 262, "start_aa": "Asn", "end_pos": 262, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn262", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Asn329", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 329, "start_aa": "Asn", "end_pos": 329, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn329", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Asn374", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 374, "start_aa": "Asn", "end_pos": 374, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn374", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Asn419", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 419, "start_aa": "Asn", "end_pos": 419, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn419", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "464", "end_pos": "464", "site_lbl": "Asn464", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 464, "start_aa": "Asn", "end_pos": 464, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn464", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "509", "end_pos": "509", "site_lbl": "Asn509", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 509, "start_aa": "Asn", "end_pos": 509, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn509", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "554", "end_pos": "554", "site_lbl": "Asn554", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 554, "start_aa": "Asn", "end_pos": 554, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn554", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Asn599", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 599, "start_aa": "Asn", "end_pos": 599, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn599", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "644", "end_pos": "644", "site_lbl": "Asn644", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 644, "start_aa": "Asn", "end_pos": 644, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn644", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "689", "end_pos": "689", "site_lbl": "Asn689", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 689, "start_aa": "Asn", "end_pos": 689, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn689", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32768-1", "start_pos": "734", "end_pos": "734", "site_lbl": "Asn734", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 734, "start_aa": "Asn", "end_pos": 734, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn734", "evidence": [ { "id": "P32768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32768#ptm_processing" } ] } ] } ], "record_id": "P32768-1" }, { "uniprot_canonical_ac": "P32769-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 611, "chemical_mass": 68730.0, "gene_names": "HBS1;HBS1;YKR404", "protein_name": "Elongation factor 1 alpha-like protein", "disease": [ { "disease_id": "DOID:12241", "name": "beta thalassemia", "description": "A thalassemia characterized by the reduced or absent synthesis of the beta globin chains of hemoglobin.", "url": "https://disease-ontology.org/term/DOID:12241", "evidence": [ { "id": "12241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12241" } ], "weight": 0.0 } ], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" }, { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" }, { "name": "nonfunctional rRNA decay", "id": "GO:0070651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070651", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, no-go decay", "id": "GO:0070966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070966", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" }, { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" }, { "name": "Dom34-Hbs1 complex", "id": "GO:1990533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990533", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32769-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32769", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32769" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001792", "url": "https://www.yeastgenome.org/locus/S000001792" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32769-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001792", "url": "https://www.yeastgenome.org/locus/S000001792" }, { "database": "iPTMnet", "id": "P32769", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32769" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32769-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Thr248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32769", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32769" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001792", "url": "https://www.yeastgenome.org/locus/S000001792" } ] } ] }, { "uniprot_canonical_ac": "P32769-1", "start_pos": "543", "end_pos": "543", "site_lbl": "Ser543", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001792", "url": "https://www.yeastgenome.org/locus/S000001792" }, { "database": "iPTMnet", "id": "P32769", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32769" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32769-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Val176", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "G", "comment": "Loss of function. Abolished GTP-binding and ability to trigger the No-Go Decay (NGD) pathway and promote degradation of non-functional rRNAs.", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" }, { "database": "PubMed", "id": "11909951", "url": "https://glygen.org/publication/PubMed/11909951" }, { "database": "PubMed", "id": "21102444", "url": "https://glygen.org/publication/PubMed/21102444" } ] } ] }, { "uniprot_canonical_ac": "P32769-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Lys180", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Abolished GTP-binding and ability to trigger the No-Go Decay (NGD) pathway and promote degradation of non-functional rRNAs.", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" }, { "database": "PubMed", "id": "21102444", "url": "https://glygen.org/publication/PubMed/21102444" } ] } ] }, { "uniprot_canonical_ac": "P32769-1", "start_pos": "255", "end_pos": "255", "site_lbl": "His255", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "E", "comment": "Loss of function. Abolished GTP-binding and ability to trigger the No-Go Decay (NGD) pathway and promote degradation of non-functional rRNAs.", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" }, { "database": "PubMed", "id": "11909951", "url": "https://glygen.org/publication/PubMed/11909951" }, { "database": "PubMed", "id": "21102444", "url": "https://glygen.org/publication/PubMed/21102444" } ] } ] }, { "uniprot_canonical_ac": "P32769-1", "start_pos": "517", "end_pos": "517", "site_lbl": "Arg517", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Abolished ability to trigger the No-Go Decay (NGD) pathway, without affecting the ability to promote degradation of non-functional rRNAs.", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" }, { "database": "PubMed", "id": "21102444", "url": "https://glygen.org/publication/PubMed/21102444" } ] } ] }, { "uniprot_canonical_ac": "P32769-1", "start_pos": "520", "end_pos": "520", "site_lbl": "Leu520", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "R", "comment": "Abolished ability to trigger the No-Go Decay (NGD) pathway, without affecting the ability to promote degradation of non-functional rRNAs.", "evidence": [ { "database": "UniProtKB", "id": "P32769", "url": "https://www.uniprot.org/uniprotkb/P32769" }, { "database": "PubMed", "id": "21102444", "url": "https://glygen.org/publication/PubMed/21102444" } ] } ] } ], "record_id": "P32769-1" }, { "uniprot_canonical_ac": "P32771-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 386, "chemical_mass": 41042.0, "gene_names": "SFA1;ADH5;SFA1;SFA", "protein_name": "S-(hydroxymethyl)glutathione dehydrogenase", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0060892", "name": "late onset Parkinson's disease", "description": "A Parkinson's disease characterized by onset of motor symptoms typically after 60 years of age.", "url": "https://disease-ontology.org/term/DOID:0060892", "evidence": [ { "id": "0060892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060892" } ], "weight": 0.0 }, { "disease_id": "DOID:0080952", "name": "AMED syndrome", "description": "A syndrome that is characterized by global developmental delay with impaired intellectual development, onset of bone marrow failure and myelodysplastic syndrome in childhood, and poor overall growth with short stature and that has_material_basis_in homozygous or compound heterozygous mutation in the ADH5 gene on chromosome 4q accompanied by a specific homozygous or heterozygous allele in the ALDH2 gene (E504K) on chromosome 12q24. Defects in both of these genes are necessary for the disorder to manifest, consistent with digenic inheritance.", "url": "https://disease-ontology.org/term/DOID:0080952", "evidence": [ { "id": "0080952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080952" } ], "weight": 0.0 }, { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "alcohol dehydrogenase (NAD+) activity", "id": "GO:0004022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004022", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" }, { "name": "S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity", "id": "GO:0051903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051903", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" }, { "name": "S-nitrosoglutathione reductase (NADH) activity", "id": "GO:0080007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080007", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" }, { "name": "S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity", "id": "GO:0106321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106321", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" }, { "name": "S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity", "id": "GO:0106322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106322", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" }, { "name": "hydroxymethylfurfural reductase (NADH) activity", "id": "GO:0033833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033833", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" } ], "biological_process": [ { "name": "formaldehyde catabolic process", "id": "GO:0046294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046294", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" }, { "name": "amino acid catabolic process to alcohol via Ehrlich pathway", "id": "GO:0000947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000947", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" }, { "name": "furaldehyde metabolic process", "id": "GO:0033859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033859", "evidence": [ { "database": "UniProtKB", "id": "P32771", "url": "https://www.uniprot.org/uniprotkb/P32771" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32771-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002327", "url": "https://www.yeastgenome.org/locus/S000002327" }, { "database": "iPTMnet", "id": "P32771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32771-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Ser382", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002327", "url": "https://www.yeastgenome.org/locus/S000002327" }, { "database": "iPTMnet", "id": "P32771", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32771-1" }, { "uniprot_canonical_ac": "P32773-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 286, "chemical_mass": 32201.0, "gene_names": "TOA1;TOA1", "protein_name": "Transcription initiation factor IIA large subunit", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" }, { "name": "transcription factor TFIIA complex", "id": "GO:0005672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005672", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II core promoter sequence-specific DNA binding", "id": "GO:0000979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000979", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" }, { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "P32773", "url": "https://www.uniprot.org/uniprotkb/P32773" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32773-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32773", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32773" }, { "database": "PubMed", "id": "10082550", "url": "https://glygen.org/publication/PubMed/10082550" } ] } ] }, { "uniprot_canonical_ac": "P32773-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32773", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32773" }, { "database": "PubMed", "id": "10082550", "url": "https://glygen.org/publication/PubMed/10082550" } ] } ] }, { "uniprot_canonical_ac": "P32773-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Ser232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32773", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32773" }, { "database": "PubMed", "id": "10082550", "url": "https://glygen.org/publication/PubMed/10082550" }, { "database": "SGD", "id": "S000005720", "url": "https://www.yeastgenome.org/locus/S000005720" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32773-1" }, { "uniprot_canonical_ac": "P32781-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32781", "url": "https://www.uniprot.org/uniprotkb/P32781" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 87, "chemical_mass": 9464.0, "gene_names": "AGA2;AGA2", "protein_name": "A-agglutinin-binding subunit", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32781", "url": "https://www.uniprot.org/uniprotkb/P32781" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P32781", "url": "https://www.uniprot.org/uniprotkb/P32781" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P32781", "url": "https://www.uniprot.org/uniprotkb/P32781" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "P32781", "url": "https://www.uniprot.org/uniprotkb/P32781" } ], "pmid": "" } ], "biological_process": [ { "name": "agglutination involved in conjugation with cellular fusion", "id": "GO:0000752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000752", "evidence": [ { "database": "UniProtKB", "id": "P32781", "url": "https://www.uniprot.org/uniprotkb/P32781" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32781-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-mannosylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man...) threonine;O-mannosylation", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "P32781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32781-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-mannosylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man...) serine;O-mannosylation", "icn3d_view": {}, "start_pos": 30, "start_aa": "Ser", "end_pos": 30, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser30", "evidence": [ { "id": "P32781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32781-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Thr32", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-mannosylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man...) threonine;O-mannosylation", "icn3d_view": {}, "start_pos": 32, "start_aa": "Thr", "end_pos": 32, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr32", "evidence": [ { "id": "P32781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32781-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-mannosylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man...) serine;O-mannosylation", "icn3d_view": {}, "start_pos": 39, "start_aa": "Ser", "end_pos": 39, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser39", "evidence": [ { "id": "P32781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32781-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Thr63", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-mannosylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man...) threonine;O-mannosylation", "icn3d_view": {}, "start_pos": 63, "start_aa": "Thr", "end_pos": 63, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr63", "evidence": [ { "id": "P32781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32781-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-mannosylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man...) serine;O-mannosylation", "icn3d_view": {}, "start_pos": 66, "start_aa": "Ser", "end_pos": 66, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser66", "evidence": [ { "id": "P32781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32781-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-mannosylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man...) threonine;O-mannosylation", "icn3d_view": {}, "start_pos": 75, "start_aa": "Thr", "end_pos": 75, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr75", "evidence": [ { "id": "P32781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32781-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Cys25", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes agglutination; when associated with S-68.", "evidence": [ { "database": "UniProtKB", "id": "P32781", "url": "https://www.uniprot.org/uniprotkb/P32781" }, { "database": "PubMed", "id": "7957044", "url": "https://glygen.org/publication/PubMed/7957044" } ] } ] }, { "uniprot_canonical_ac": "P32781-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Cys68", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes agglutination; when associated with S-25.", "evidence": [ { "database": "UniProtKB", "id": "P32781", "url": "https://www.uniprot.org/uniprotkb/P32781" }, { "database": "PubMed", "id": "7957044", "url": "https://glygen.org/publication/PubMed/7957044" } ] } ] } ], "record_id": "P32781-1" }, { "uniprot_canonical_ac": "P32783-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 436, "chemical_mass": 50341.0, "gene_names": "ABD1;ABD1;YBR1602", "protein_name": "mRNA cap guanine-N(7) methyltransferase", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" } ], "pmid": "" }, { "name": "mRNA 5'-cap (guanine-N7-)-methyltransferase activity", "id": "GO:0004482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004482", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" } ], "pmid": "" } ], "biological_process": [ { "name": "7-methylguanosine mRNA capping", "id": "GO:0006370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006370", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32783-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000440", "url": "https://www.yeastgenome.org/locus/S000000440" }, { "database": "iPTMnet", "id": "P32783", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32783" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P32783", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32783" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P32783", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32783" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000440", "url": "https://www.yeastgenome.org/locus/S000000440" }, { "database": "iPTMnet", "id": "P32783", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32783" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000440", "url": "https://www.yeastgenome.org/locus/S000000440" }, { "database": "iPTMnet", "id": "P32783", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32783" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000440", "url": "https://www.yeastgenome.org/locus/S000000440" }, { "database": "iPTMnet", "id": "P32783", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32783" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000440", "url": "https://www.yeastgenome.org/locus/S000000440" }, { "database": "iPTMnet", "id": "P32783", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32783" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Val168", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Glu170", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Non-viable; reduced enzyme activity to 8% of wild-type.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "11472630", "url": "https://glygen.org/publication/PubMed/11472630" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] }, { "sequence_org": "E", "sequence_mut": "D", "comment": "Still viable; increase in activity.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "11472630", "url": "https://glygen.org/publication/PubMed/11472630" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] }, { "sequence_org": "E", "sequence_mut": "Q", "comment": "Non-viable; reduced enzyme activity to 8% of wild-type.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "11472630", "url": "https://glygen.org/publication/PubMed/11472630" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Gly172", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Gly174", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Non viable; no growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "8552073", "url": "https://glygen.org/publication/PubMed/8552073" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Gly176", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Asp178", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Microcolony formation.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "8552073", "url": "https://glygen.org/publication/PubMed/8552073" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Lys181", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Tyr182", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Asp194", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Lethal; no enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "11472630", "url": "https://glygen.org/publication/PubMed/11472630" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] }, { "sequence_org": "D", "sequence_mut": "E", "comment": "Still viable; activity near to wild-type.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "11472630", "url": "https://glygen.org/publication/PubMed/11472630" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Lethal; no enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "11472630", "url": "https://glygen.org/publication/PubMed/11472630" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Arg206", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Lethal.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "11472630", "url": "https://glygen.org/publication/PubMed/11472630" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] }, { "sequence_org": "R", "sequence_mut": "K", "comment": "Still viable; little change in enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "11472630", "url": "https://glygen.org/publication/PubMed/11472630" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "253", "end_pos": "253", "site_lbl": "His253", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "8552073", "url": "https://glygen.org/publication/PubMed/8552073" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Tyr254", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Non viable; no growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "8552073", "url": "https://glygen.org/publication/PubMed/8552073" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] }, { "sequence_org": "Y", "sequence_mut": "F", "comment": "Still viable; slow growth; near to wild-type enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "8552073", "url": "https://glygen.org/publication/PubMed/8552073" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] }, { "sequence_org": "Y", "sequence_mut": "S", "comment": "Lethal; Enzyme activity 10% of wild-type.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "8552073", "url": "https://glygen.org/publication/PubMed/8552073" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Gly276", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Gly277", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Thr282", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "8552073", "url": "https://glygen.org/publication/PubMed/8552073" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Glu287", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "8552073", "url": "https://glygen.org/publication/PubMed/8552073" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Glu347", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Tyr348", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Val349", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Val350", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Glu361", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "8552073", "url": "https://glygen.org/publication/PubMed/8552073" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Tyr362", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "8552073", "url": "https://glygen.org/publication/PubMed/8552073" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Gly363", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "366", "end_pos": "366", "site_lbl": "Leu366", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Val367", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] }, { "uniprot_canonical_ac": "P32783-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Phe372", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Still viable; normal growth.", "evidence": [ { "database": "UniProtKB", "id": "P32783", "url": "https://www.uniprot.org/uniprotkb/P32783" }, { "database": "PubMed", "id": "9169431", "url": "https://glygen.org/publication/PubMed/9169431" } ] } ] } ], "record_id": "P32783-1" }, { "uniprot_canonical_ac": "P32784-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32784", "url": "https://www.uniprot.org/uniprotkb/P32784" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 759, "chemical_mass": 85694.0, "gene_names": "SCT1;GAT2;SCT1;YBL0309;YBL0315", "protein_name": "Glycerol-3-phosphate O-acyltransferase 1", "disease": [], "molecular_function": [ { "name": "glycerone-phosphate O-acyltransferase activity", "id": "GO:0016287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016287", "evidence": [ { "database": "UniProtKB", "id": "P32784", "url": "https://www.uniprot.org/uniprotkb/P32784" } ], "pmid": "" }, { "name": "glycerol-3-phosphate O-acyltransferase activity", "id": "GO:0004366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004366", "evidence": [ { "database": "UniProtKB", "id": "P32784", "url": "https://www.uniprot.org/uniprotkb/P32784" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32784", "url": "https://www.uniprot.org/uniprotkb/P32784" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32784", "url": "https://www.uniprot.org/uniprotkb/P32784" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "P32784", "url": "https://www.uniprot.org/uniprotkb/P32784" } ], "pmid": "" }, { "name": "CDP-diacylglycerol biosynthetic process", "id": "GO:0016024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016024", "evidence": [ { "database": "UniProtKB", "id": "P32784", "url": "https://www.uniprot.org/uniprotkb/P32784" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32784-1", "start_pos": "639", "end_pos": "639", "site_lbl": "Ser639", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32784", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32784" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32784-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Ser640", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32784", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32784" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000107", "url": "https://www.yeastgenome.org/locus/S000000107" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32784-1", "start_pos": "641", "end_pos": "641", "site_lbl": "Ser641", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32784", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32784" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000107", "url": "https://www.yeastgenome.org/locus/S000000107" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32784-1", "start_pos": "660", "end_pos": "660", "site_lbl": "Ser660", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000107", "url": "https://www.yeastgenome.org/locus/S000000107" }, { "database": "iPTMnet", "id": "P32784", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32784" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32784-1", "start_pos": "699", "end_pos": "699", "site_lbl": "Ser699", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000107", "url": "https://www.yeastgenome.org/locus/S000000107" }, { "database": "iPTMnet", "id": "P32784", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32784" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32784-1", "start_pos": "701", "end_pos": "701", "site_lbl": "Ser701", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000107", "url": "https://www.yeastgenome.org/locus/S000000107" }, { "database": "iPTMnet", "id": "P32784", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32784" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32784-1", "start_pos": "733", "end_pos": "733", "site_lbl": "Thr733", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000107", "url": "https://www.yeastgenome.org/locus/S000000107" }, { "database": "iPTMnet", "id": "P32784", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32784" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P32784-1" }, { "uniprot_canonical_ac": "P32789-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 676, "chemical_mass": 76372.0, "gene_names": "ALK2;ALK2;YBL0317", "protein_name": "Serine/threonine-protein kinase Haspin homolog ALK2", "disease": [], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "pmid": "" }, { "name": "mitotic morphogenesis checkpoint signaling", "id": "GO:0044879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044879", "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "pmid": "" }, { "name": "histone H3T3 kinase activity", "id": "GO:0072354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072354", "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32789", "url": "https://www.uniprot.org/uniprotkb/P32789" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32789-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Ser131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Ser253", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Ser274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Thr284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Ser297", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Thr305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "331", "end_pos": "331", "site_lbl": "Thr331", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Thr403", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Thr51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Thr72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32789-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Ser93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000105", "url": "https://www.yeastgenome.org/locus/S000000105" }, { "database": "iPTMnet", "id": "P32789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32789" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] } ], "record_id": "P32789-1" }, { "uniprot_canonical_ac": "P32796-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32796", "url": "https://www.uniprot.org/uniprotkb/P32796" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 670, "chemical_mass": 77242.0, "gene_names": "CAT2;CAT2;CAT;YCAT;YM8054.01", "protein_name": "Carnitine O-acetyltransferase, mitochondrial", "disease": [ { "disease_id": "DOID:0110671", "name": "congenital myasthenic syndrome 6", "description": "A congenital myasthenic syndrome characterized by autosomal recessive inheritance of a presynaptic defect resulting in onset of muscle weakeness in infancy or early childhood and a tendency to have sudden apneic episodes that has_material_basis_in homozygous or compound heterozygous mutation in the CHAT gene on chromosome 10q.", "url": "https://disease-ontology.org/term/DOID:0110671", "evidence": [ { "id": "0110671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110671" } ], "weight": 0.0 }, { "disease_id": "DOID:0110734", "name": "neurodegeneration with brain iron accumulation", "description": "A neurodegenerative disease characterized by progressive iron accumulation in the basal ganglia and other regions of the brain, resulting in extrapyramidal movements, such as parkinsonism and dystonia.", "url": "https://disease-ontology.org/term/DOID:0110734", "evidence": [ { "id": "0110734", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110734" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3635", "name": "congenital myasthenic syndrome", "description": "A neuromuscular junction disease that is characterized by weakness and easy fatiguability resulting from a genetic defect at the junction where the nerve stimulates muscle activity that result in muscle weakness and may affect nerve cells (presynaptic), muscle cells (postsynaptic) or the space between nerve and muscle cells (synaptic).", "url": "https://disease-ontology.org/term/DOID:3635", "evidence": [ { "id": "3635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3635" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32796", "url": "https://www.uniprot.org/uniprotkb/P32796" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P32796", "url": "https://www.uniprot.org/uniprotkb/P32796" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P32796", "url": "https://www.uniprot.org/uniprotkb/P32796" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "P32796", "url": "https://www.uniprot.org/uniprotkb/P32796" } ], "pmid": "" }, { "name": "carnitine metabolic process", "id": "GO:0009437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009437", "evidence": [ { "database": "UniProtKB", "id": "P32796", "url": "https://www.uniprot.org/uniprotkb/P32796" } ], "pmid": "" } ], "molecular_function": [ { "name": "carnitine O-acetyltransferase activity", "id": "GO:0004092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004092", "evidence": [ { "database": "UniProtKB", "id": "P32796", "url": "https://www.uniprot.org/uniprotkb/P32796" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32796-1" }, { "uniprot_canonical_ac": "P32798-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 439, "chemical_mass": 48155.0, "gene_names": "COT1;COT1;O6131", "protein_name": "Vacuolar zinc transporter COT1", "disease": [ { "disease_id": "DOID:0080536", "name": "hypermanganesemia with dystonia 1", "description": "A hypermanganesemia with dystonia that is characterized by increased serum manganese, motor neurodegeneration with extrapyramidal features, polycythemia, and hepatic dysfunction and has_material_basis_in homozygous mutation in the SLC30A10 gene on chromosome 1q41.", "url": "https://disease-ontology.org/term/DOID:0080536", "evidence": [ { "id": "0080536", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080536" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "pmid": "" }, { "name": "cobalt ion transmembrane transporter activity", "id": "GO:0015087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015087", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "pmid": "" } ], "biological_process": [ { "name": "zinc ion transmembrane transport", "id": "GO:0071577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071577", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "pmid": "" }, { "name": "zinc ion transport", "id": "GO:0006829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006829", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "pmid": "" }, { "name": "intracellular zinc ion homeostasis", "id": "GO:0006882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006882", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "pmid": "" }, { "name": "cobalt ion transport", "id": "GO:0006824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006824", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32798-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005843", "url": "https://www.yeastgenome.org/locus/S000005843" }, { "database": "iPTMnet", "id": "P32798", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32798" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32798-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Thr206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005843", "url": "https://www.yeastgenome.org/locus/S000005843" }, { "database": "iPTMnet", "id": "P32798", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32798" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32798-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005843", "url": "https://www.yeastgenome.org/locus/S000005843" }, { "database": "iPTMnet", "id": "P32798", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32798" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32798-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005843", "url": "https://www.yeastgenome.org/locus/S000005843" }, { "database": "iPTMnet", "id": "P32798", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32798-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Thr222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005843", "url": "https://www.yeastgenome.org/locus/S000005843" }, { "database": "iPTMnet", "id": "P32798", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32798-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32798", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32798" }, { "database": "SGD", "id": "S000005843", "url": "https://www.yeastgenome.org/locus/S000005843" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32798-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Ser389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005843", "url": "https://www.yeastgenome.org/locus/S000005843" }, { "database": "iPTMnet", "id": "P32798", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32798" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32798-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005843", "url": "https://www.yeastgenome.org/locus/S000005843" }, { "database": "iPTMnet", "id": "P32798", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32798-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005843", "url": "https://www.yeastgenome.org/locus/S000005843" }, { "database": "iPTMnet", "id": "P32798", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32798-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Asn45", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "I", "comment": "Increases ability to transport iron and decreases ability to transport cobalt.", "evidence": [ { "database": "UniProtKB", "id": "P32798", "url": "https://www.uniprot.org/uniprotkb/P32798" }, { "database": "PubMed", "id": "18930916", "url": "https://glygen.org/publication/PubMed/18930916" } ] } ] } ], "record_id": "P32798-1" }, { "uniprot_canonical_ac": "P32801-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 640, "chemical_mass": 72150.0, "gene_names": "ELM1;ELM1;LDB9;YKL261", "protein_name": "Serine/threonine-protein kinase ELM1", "disease": [], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "cellular bud neck septin ring", "id": "GO:0000144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000144", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" } ], "biological_process": [ { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "septin ring assembly", "id": "GO:0000921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000921", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "maltose metabolic process", "id": "GO:0000023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000023", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "budding cell bud growth", "id": "GO:0007117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007117", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "pseudohyphal growth", "id": "GO:0007124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007124", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" }, { "name": "protein localization to septin ring", "id": "GO:1902935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902935", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32801-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Thr148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Thr149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Ser152", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Ser489", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "516", "end_pos": "516", "site_lbl": "Ser516", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "519", "end_pos": "519", "site_lbl": "Ser519", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Thr551", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "PubMed", "id": "18231587", "url": "https://glygen.org/publication/PubMed/18231587" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "561", "end_pos": "561", "site_lbl": "Ser561", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "562", "end_pos": "562", "site_lbl": "Ser562", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "580", "end_pos": "580", "site_lbl": "Ser580", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "581", "end_pos": "581", "site_lbl": "Ser581", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001531", "url": "https://www.yeastgenome.org/locus/S000001531" }, { "database": "iPTMnet", "id": "P32801", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32801" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32801-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Thr200", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "G", "comment": "Allows selective inhibition in vivo.", "evidence": [ { "database": "UniProtKB", "id": "P32801", "url": "https://www.uniprot.org/uniprotkb/P32801" }, { "database": "PubMed", "id": "12917352", "url": "https://glygen.org/publication/PubMed/12917352" } ] } ] } ], "record_id": "P32801-1" }, { "uniprot_canonical_ac": "P32802-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 667, "chemical_mass": 75963.0, "gene_names": "EMP70;EMP70;L2385;L9449.11;TMN1", "protein_name": "Transmembrane 9 superfamily member 1", "disease": [ { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "biological_process": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "pmid": "" }, { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "pmid": "" }, { "name": "intracellular copper ion homeostasis", "id": "GO:0006878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006878", "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "pmid": "" }, { "name": "invasive growth in response to glucose limitation", "id": "GO:0001403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001403", "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "pmid": "" }, { "name": "pseudohyphal growth", "id": "GO:0007124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007124", "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "pmid": "" } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P32802", "url": "https://www.uniprot.org/uniprotkb/P32802" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32802-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Asn282", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 282, "start_aa": "Asn", "end_pos": 282, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn282", "evidence": [ { "id": "P32802", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32802#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P32802-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Asn61", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 61, "start_aa": "Asn", "end_pos": 61, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn61", "evidence": [ { "id": "P32802", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32802#ptm_processing" } ] } ] } ], "record_id": "P32802-1" }, { "uniprot_canonical_ac": "P32803-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 203, "chemical_mass": 23332.0, "gene_names": "EMP24;BST2;EMP24;G1271", "protein_name": "Endosomal protein P24B", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "Golgi-associated vesicle", "id": "GO:0005798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005798", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "vesicle budding from membrane", "id": "GO:0006900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006900", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "vesicle organization", "id": "GO:0016050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016050", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" }, { "name": "protein retention in ER lumen", "id": "GO:0006621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006621", "evidence": [ { "database": "UniProtKB", "id": "P32803", "url": "https://www.uniprot.org/uniprotkb/P32803" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32803-1" }, { "uniprot_canonical_ac": "P32804-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32804", "url": "https://www.uniprot.org/uniprotkb/P32804" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 376, "chemical_mass": 41582.0, "gene_names": "ZRT1;NRC376;ZRT1", "protein_name": "High-affinity zinc transporter ZRT1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32804", "url": "https://www.uniprot.org/uniprotkb/P32804" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32804", "url": "https://www.uniprot.org/uniprotkb/P32804" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32804", "url": "https://www.uniprot.org/uniprotkb/P32804" } ], "pmid": "" } ], "biological_process": [ { "name": "zinc ion import across plasma membrane", "id": "GO:0071578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071578", "evidence": [ { "database": "UniProtKB", "id": "P32804", "url": "https://www.uniprot.org/uniprotkb/P32804" } ], "pmid": "" } ], "molecular_function": [ { "name": "high-affinity zinc transmembrane transporter activity", "id": "GO:0000006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000006", "evidence": [ { "database": "UniProtKB", "id": "P32804", "url": "https://www.uniprot.org/uniprotkb/P32804" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32804-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Tyr155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32804", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32804" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003224", "url": "https://www.yeastgenome.org/locus/S000003224" } ] } ] }, { "uniprot_canonical_ac": "P32804-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Thr162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32804", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32804" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003224", "url": "https://www.yeastgenome.org/locus/S000003224" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32804-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Thr169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32804", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32804" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003224", "url": "https://www.yeastgenome.org/locus/S000003224" } ] } ] }, { "uniprot_canonical_ac": "P32804-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Ser178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32804", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32804" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003224", "url": "https://www.yeastgenome.org/locus/S000003224" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32804-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32804", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32804" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003224", "url": "https://www.yeastgenome.org/locus/S000003224" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32804-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Thr187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32804", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32804" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000003224", "url": "https://www.yeastgenome.org/locus/S000003224" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32804-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003224", "url": "https://www.yeastgenome.org/locus/S000003224" }, { "database": "iPTMnet", "id": "P32804", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32804" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32804-1" }, { "uniprot_canonical_ac": "P32807-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 602, "chemical_mass": 70647.0, "gene_names": "YKU70;HDF1;NES24;YKU70;YM8021.10", "protein_name": "ATP-dependent DNA helicase II subunit 1", "disease": [ { "disease_id": "DOID:1749", "name": "squamous cell carcinoma", "description": "A carcinoma that derives_from squamous epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1749", "evidence": [ { "id": "1749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1749" } ], "weight": 0.0 }, { "disease_id": "DOID:2513", "name": "basal cell carcinoma", "description": "A skin carcinoma affecting basal cells.", "url": "https://disease-ontology.org/term/DOID:2513", "evidence": [ { "id": "2513", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2513" } ], "weight": 0.0 } ], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "recombinational repair", "id": "GO:0000725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000725", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "establishment of protein-containing complex localization to telomere", "id": "GO:0097695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097695", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "mitochondrial double-strand break repair via homologous recombination", "id": "GO:0097552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097552", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "telomerase RNA binding", "id": "GO:0070034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070034", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" }, { "name": "Ku70:Ku80 complex", "id": "GO:0043564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043564", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32807-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32807" } ] } ] }, { "uniprot_canonical_ac": "P32807-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Ser371", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32807" } ] } ] }, { "uniprot_canonical_ac": "P32807-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32807", "url": "https://www.uniprot.org/uniprotkb/P32807" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32807" } ] } ] }, { "uniprot_canonical_ac": "P32807-1", "start_pos": "425", "end_pos": "425", "site_lbl": "Ser425", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004897", "url": "https://www.yeastgenome.org/locus/S000004897" }, { "database": "iPTMnet", "id": "P32807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32807" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32807-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Ser586", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004897", "url": "https://www.yeastgenome.org/locus/S000004897" }, { "database": "iPTMnet", "id": "P32807", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32807" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32807-1" }, { "uniprot_canonical_ac": "P32828-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 619, "chemical_mass": 71071.0, "gene_names": "SLX5;D2875;HEX3;SLX5;ULS2", "protein_name": "E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" }, { "name": "SUMO-targeted ubiquitin ligase complex", "id": "GO:0033768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033768", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" }, { "name": "SUMO binding", "id": "GO:0032183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032183", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32828-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 267, "start_aa": "Ser", "end_pos": 267, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser267", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32828", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32828" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002171", "url": "https://www.yeastgenome.org/locus/S000002171" }, { "database": "iPTMnet", "id": "P32828", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32828" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32828-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Ser268", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 268, "start_aa": "Ser", "end_pos": 268, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser268", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32828", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32828" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002171", "url": "https://www.yeastgenome.org/locus/S000002171" }, { "database": "iPTMnet", "id": "P32828", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32828" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32828-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ser273", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 273, "start_aa": "Ser", "end_pos": 273, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser273", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32828", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32828" } ] } ] }, { "uniprot_canonical_ac": "P32828-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Ser275", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 275, "start_aa": "Ser", "end_pos": 275, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser275", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32828", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32828" } ] } ] }, { "uniprot_canonical_ac": "P32828-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002171", "url": "https://www.yeastgenome.org/locus/S000002171" }, { "database": "iPTMnet", "id": "P32828", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32828" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32828-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32828", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32828" }, { "database": "SGD", "id": "S000002171", "url": "https://www.yeastgenome.org/locus/S000002171" } ] } ] }, { "uniprot_canonical_ac": "P32828-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002171", "url": "https://www.yeastgenome.org/locus/S000002171" }, { "database": "iPTMnet", "id": "P32828", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32828" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32828-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Thr184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002171", "url": "https://www.yeastgenome.org/locus/S000002171" }, { "database": "iPTMnet", "id": "P32828", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32828" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32828-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002171", "url": "https://www.yeastgenome.org/locus/S000002171" }, { "database": "iPTMnet", "id": "P32828", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32828" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32828-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32828", "url": "https://www.uniprot.org/uniprotkb/P32828" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32828", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32828" }, { "database": "SGD", "id": "S000002171", "url": "https://www.yeastgenome.org/locus/S000002171" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32828-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Ser402", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002171", "url": "https://www.yeastgenome.org/locus/S000002171" }, { "database": "iPTMnet", "id": "P32828", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32828" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32828-1" }, { "uniprot_canonical_ac": "P32833-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 620, "chemical_mass": 71238.0, "gene_names": "ORC2;ORC2;RRR1;SIR5;YBR0523", "protein_name": "Origin recognition complex subunit 2", "disease": [], "molecular_function": [ { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pre-replicative complex", "id": "GO:0005656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005656", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" }, { "name": "DNA replication preinitiation complex", "id": "GO:0031261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031261", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" }, { "name": "nuclear origin of replication recognition complex", "id": "GO:0005664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005664", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" } ], "biological_process": [ { "name": "pre-replicative complex assembly involved in nuclear cell cycle DNA replication", "id": "GO:0006267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006267", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" }, { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" }, { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32833-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Thr174", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 174, "start_aa": "Thr", "end_pos": 174, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr174", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Thr219", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 219, "start_aa": "Thr", "end_pos": 219, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr219", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Tyr150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Thr158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ser164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Thr187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19068484", "url": "https://glygen.org/publication/PubMed/19068484" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19068484", "url": "https://glygen.org/publication/PubMed/19068484" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "19068484", "url": "https://glygen.org/publication/PubMed/19068484" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Thr205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Thr217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Thr24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "335", "end_pos": "335", "site_lbl": "Ser335", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Tyr340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Ser341", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Ser42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Thr60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32833", "url": "https://www.uniprot.org/uniprotkb/P32833" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000264", "url": "https://www.yeastgenome.org/locus/S000000264" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32833-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P32833", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32833" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "21289063", "url": "https://glygen.org/publication/PubMed/21289063" } ] } ] } ], "record_id": "P32833-1" }, { "uniprot_canonical_ac": "P32838-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 368, "chemical_mass": 42433.0, "gene_names": "PPG1;N3281;PPG1;PPG", "protein_name": "Serine/threonine-protein phosphatase PP2A-like PPG1", "disease": [], "biological_process": [ { "name": "negative regulation of mitophagy", "id": "GO:1901525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901525", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" }, { "name": "glycogen metabolic process", "id": "GO:0005977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" }, { "name": "cellular response to pheromone", "id": "GO:0071444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071444", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" }, { "name": "regulation of TORC2 signaling", "id": "GO:1903939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903939", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" }, { "name": "FAR/SIN/STRIPAK complex", "id": "GO:0090443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090443", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "P32838", "url": "https://www.uniprot.org/uniprotkb/P32838" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32838-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005315", "url": "https://www.yeastgenome.org/locus/S000005315" }, { "database": "iPTMnet", "id": "P32838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32838" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32838-1" }, { "uniprot_canonical_ac": "P32839-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 456, "chemical_mass": 51107.0, "gene_names": "BCS1;BCS1;D9481.17", "protein_name": "Mitochondrial chaperone BCS1", "disease": [ { "disease_id": "DOID:0050677", "name": "Bjornstad syndrome", "description": "A syndrome that is characterized by early onset of hearing loss and hair loss due to pili torti, has_material_basis_in homozygous or compound heterozygous mutation in the BCS1L gene on chromosome 2q35.", "url": "https://disease-ontology.org/term/DOID:0050677", "evidence": [ { "id": "0050677", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050677" } ], "weight": 0.0 }, { "disease_id": "DOID:0080111", "name": "mitochondrial complex III deficiency nuclear type 1", "description": "A mitochondrial complex III deficiency characterized by onset at birth of lactic acidosis, hypotonia, hypoglycemia, failure to thrive, encephalopathy, and delayed psychomotor development and that has_material_basis_in homozygous or compound heterozygous mutation in the nuclear-encoded BCS1L gene on chromosome 2q35.", "url": "https://disease-ontology.org/term/DOID:0080111", "evidence": [ { "id": "0080111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080111" } ], "weight": 0.0 }, { "disease_id": "DOID:0111455", "name": "GRACILE syndrome", "description": "A mitochondrial disorder characterized by fetal growth restriction, aminoaciduria, cholestasis, iron overload, lactocidosis, and early death that has_material_basis_in homozygous or compound heterozygous mutation in the BCS1L gene on chromosome 2q35.", "url": "https://disease-ontology.org/term/DOID:0111455", "evidence": [ { "id": "0111455", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111455" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" }, { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial respiratory chain complex III assembly", "id": "GO:0034551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034551", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" }, { "name": "chaperone-mediated protein complex assembly", "id": "GO:0051131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051131", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" }, { "name": "protein insertion into mitochondrial inner membrane from matrix", "id": "GO:0032979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032979", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32839-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Ser227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32839", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32839" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P32839-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Lys273", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Abolished ATPase activity; impaired assembly of the mitochondrial respiratory chain complex III.", "evidence": [ { "database": "UniProtKB", "id": "P32839", "url": "https://www.uniprot.org/uniprotkb/P32839" }, { "database": "PubMed", "id": "10508156", "url": "https://glygen.org/publication/PubMed/10508156" } ] } ] } ], "record_id": "P32839-1" }, { "uniprot_canonical_ac": "P32842-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 164, "chemical_mass": 17037.0, "gene_names": "VMA11;CLS9;P1064;TFP3;VMA11", "protein_name": "V-type proton ATPase subunit c'", "disease": [ { "disease_id": "DOID:0070472", "name": "early-onset epilepsy 3", "description": "An epilepsy characterized by infantile or childhood onset of various types of seizures with variable global developmental delay and intellectual disability that has_material_basis_in heterozygous mutation in the ATP6V0C gene on chromosome 16p13.3.", "url": "https://disease-ontology.org/term/DOID:0070472", "evidence": [ { "id": "0070472", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070472" } ], "weight": 0.0 }, { "disease_id": "DOID:3963", "name": "thyroid gland carcinoma", "description": "A thyroid gland cancer that has_material_basis_in epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3963", "evidence": [ { "id": "3963", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3963" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V0 domain", "id": "GO:0000220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000220", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" } ], "biological_process": [ { "name": "endosomal lumen acidification", "id": "GO:0048388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048388", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" }, { "name": "Golgi lumen acidification", "id": "GO:0061795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061795", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" } ], "molecular_function": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32842-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Glu145", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "D", "comment": "Partial inactivation.", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" }, { "database": "PubMed", "id": "9030535", "url": "https://glygen.org/publication/PubMed/9030535" } ] }, { "sequence_org": "E", "sequence_mut": "L", "comment": "Inactivation.", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" }, { "database": "PubMed", "id": "9030535", "url": "https://glygen.org/publication/PubMed/9030535" } ] }, { "sequence_org": "E", "sequence_mut": "Q", "comment": "Inactivation.", "evidence": [ { "database": "UniProtKB", "id": "P32842", "url": "https://www.uniprot.org/uniprotkb/P32842" }, { "database": "PubMed", "id": "9030535", "url": "https://glygen.org/publication/PubMed/9030535" } ] } ] } ], "record_id": "P32842-1" }, { "uniprot_canonical_ac": "P32849-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1169, "chemical_mass": 134002.0, "gene_names": "RAD5;RAD5;REV2;SNM2", "protein_name": "DNA-dependent ATPase/E3 ubiquitin-protein ligase RAD5", "disease": [ { "disease_id": "DOID:3119", "name": "gastrointestinal system cancer", "description": "An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system.", "url": "https://disease-ontology.org/term/DOID:3119", "evidence": [ { "id": "3119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3119" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "Y-form DNA binding", "id": "GO:0000403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000403", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "four-way junction helicase activity", "id": "GO:0009378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009378", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "translesion synthesis", "id": "GO:0019985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019985", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "free ubiquitin chain polymerization", "id": "GO:0010994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010994", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "DNA damage tolerance", "id": "GO:0006301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006301", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "error-free translesion synthesis", "id": "GO:0070987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070987", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "error-free postreplication DNA repair", "id": "GO:0042275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042275", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" }, { "name": "replication fork reversal", "id": "GO:0071932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071932", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32849-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "30256854", "url": "https://glygen.org/publication/PubMed/30256854" }, { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "30256854", "url": "https://glygen.org/publication/PubMed/30256854" }, { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Thr144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Thr325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Thr327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Ser368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Ser416", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Ser460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "799", "end_pos": "799", "site_lbl": "Ser799", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "850", "end_pos": "850", "site_lbl": "Ser850", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004022", "url": "https://www.yeastgenome.org/locus/S000004022" }, { "database": "iPTMnet", "id": "P32849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32849" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "1106", "end_pos": "1106", "site_lbl": "Gln1106", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "D", "comment": "Impairs DNA-dependent ATPase activity but does not affect polyubiqitination of POL30/PCNA. Sensitive to methyl methanesulfonate.", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "25690888", "url": "https://glygen.org/publication/PubMed/25690888" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Phe13", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Abolishes the interaction with REV1 but the interaction with POL30/PCNA is unaffected. Decreases the rate of UV-induced mutagenesis.", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "27001510", "url": "https://glygen.org/publication/PubMed/27001510" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Arg187", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Sensitive to cisplatin. Abolishes interaction with POL30/PCNA, impairs replication fork regression activity, abolishes its localization to chromatin, and leads to sensitivity to methyl methanesulfonate and hydroxyurea; when associated with E-229 and E-241.", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "33436623", "url": "https://glygen.org/publication/PubMed/33436623" }, { "database": "PubMed", "id": "31350889", "url": "https://glygen.org/publication/PubMed/31350889" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Arg229", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Abolishes interaction with POL30/PCNA, impairs replication fork regression activity, abolishes its localization to chromatin, and leads to sensitivity to methyl methanesulfonate and hydroxyurea; when associated with E-187 and E-241.", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "33436623", "url": "https://glygen.org/publication/PubMed/33436623" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Arg241", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Abolishes interaction with POL30/PCNA, impairs replication fork regression activity, abolishes its localization to chromatin, and leads to sensitivity to methyl methanesulfonate and hydroxyurea; when associated with E-187 and E-229.", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "33436623", "url": "https://glygen.org/publication/PubMed/33436623" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "914", "end_pos": "914", "site_lbl": "Cys914", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes interaction with UBC13.", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "12496280", "url": "https://glygen.org/publication/PubMed/12496280" }, { "database": "PubMed", "id": "10880451", "url": "https://glygen.org/publication/PubMed/10880451" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "916", "end_pos": "916", "site_lbl": "Ile916", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "A", "comment": "Abolishes interaction with UBC13. Increases the rate of UV-induced mutagenesis. Mildly sensitive to methyl methanesulfonate. No increased sensitivity to hydroxyurea.", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "12496280", "url": "https://glygen.org/publication/PubMed/12496280" }, { "database": "PubMed", "id": "27001510", "url": "https://glygen.org/publication/PubMed/27001510" }, { "database": "PubMed", "id": "37594077", "url": "https://glygen.org/publication/PubMed/37594077" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "944", "end_pos": "944", "site_lbl": "Tyr944", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes interaction with UBC13.", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "12496280", "url": "https://glygen.org/publication/PubMed/12496280" } ] } ] }, { "uniprot_canonical_ac": "P32849-1", "start_pos": "959", "end_pos": "959", "site_lbl": "Asn959", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Abolishes interaction with UBC13.", "evidence": [ { "database": "UniProtKB", "id": "P32849", "url": "https://www.uniprot.org/uniprotkb/P32849" }, { "database": "PubMed", "id": "12496280", "url": "https://glygen.org/publication/PubMed/12496280" } ] } ] } ], "record_id": "P32849-1" }, { "uniprot_canonical_ac": "P32854-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 288, "chemical_mass": 33006.0, "gene_names": "PEP12;OR26.29;PEP12;VPL6;VPS6;VPT13", "protein_name": "Syntaxin PEP12", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 } ], "biological_process": [ { "name": "Golgi vesicle fusion to target membrane", "id": "GO:0048210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048210", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "vacuole inheritance", "id": "GO:0000011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000011", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "vesicle docking", "id": "GO:0048278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048278", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" }, { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32854-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005562", "url": "https://www.yeastgenome.org/locus/S000005562" }, { "database": "iPTMnet", "id": "P32854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32854" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32854-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005562", "url": "https://www.yeastgenome.org/locus/S000005562" }, { "database": "iPTMnet", "id": "P32854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32854" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32854-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005562", "url": "https://www.yeastgenome.org/locus/S000005562" }, { "database": "iPTMnet", "id": "P32854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32854" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32854-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005562", "url": "https://www.yeastgenome.org/locus/S000005562" }, { "database": "iPTMnet", "id": "P32854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32854" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32854-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32854" }, { "database": "SGD", "id": "S000005562", "url": "https://www.yeastgenome.org/locus/S000005562" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32854-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32854" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005562", "url": "https://www.yeastgenome.org/locus/S000005562" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32854-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Leu271", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Increases ubiquitination by TUL1.", "evidence": [ { "database": "UniProtKB", "id": "P32854", "url": "https://www.uniprot.org/uniprotkb/P32854" }, { "database": "PubMed", "id": "11788821", "url": "https://glygen.org/publication/PubMed/11788821" } ] } ] } ], "record_id": "P32854-1" }, { "uniprot_canonical_ac": "P32855-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1065, "chemical_mass": 122225.0, "gene_names": "SEC8;SEC8;YP9499.11", "protein_name": "Exocyst complex component SEC8", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "vesicle tethering involved in exocytosis", "id": "GO:0090522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090522", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "Golgi inheritance", "id": "GO:0048313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048313", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" }, { "name": "endoplasmic reticulum inheritance", "id": "GO:0048309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048309", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32855-1", "start_pos": "1022", "end_pos": "1022", "site_lbl": "Ser1022", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1022, "start_aa": "Ser", "end_pos": 1022, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1022", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32855", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32855" } ] } ] }, { "uniprot_canonical_ac": "P32855-1", "start_pos": "1041", "end_pos": "1041", "site_lbl": "Ser1041", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006259", "url": "https://www.yeastgenome.org/locus/S000006259" }, { "database": "iPTMnet", "id": "P32855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32855" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32855-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32855" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000006259", "url": "https://www.yeastgenome.org/locus/S000006259" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32855-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32855", "url": "https://www.uniprot.org/uniprotkb/P32855" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32855" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006259", "url": "https://www.yeastgenome.org/locus/S000006259" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32855-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32855" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006259", "url": "https://www.yeastgenome.org/locus/S000006259" } ] } ] }, { "uniprot_canonical_ac": "P32855-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Thr23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32855" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006259", "url": "https://www.yeastgenome.org/locus/S000006259" } ] } ] }, { "uniprot_canonical_ac": "P32855-1", "start_pos": "502", "end_pos": "502", "site_lbl": "Ser502", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006259", "url": "https://www.yeastgenome.org/locus/S000006259" }, { "database": "iPTMnet", "id": "P32855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32855" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32855-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Ser538", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006259", "url": "https://www.yeastgenome.org/locus/S000006259" }, { "database": "iPTMnet", "id": "P32855", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32855" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32855-1" }, { "uniprot_canonical_ac": "P32860-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32860", "url": "https://www.uniprot.org/uniprotkb/P32860" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 256, "chemical_mass": 29174.0, "gene_names": "NFU1;NFU1;NUB1;YKL253", "protein_name": "NifU-like protein, mitochondrial", "disease": [ { "disease_id": "DOID:0070645", "name": "hereditary spastic paraplegia 93", "description": "A hereditary spastic paraplegia that has_material_basis_in homozygous or compound heterozygous mutation in the NFU1 gene on chromosome 2p13.", "url": "https://disease-ontology.org/term/DOID:0070645", "evidence": [ { "id": "0070645", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070645" } ], "weight": 0.0 }, { "disease_id": "DOID:0080133", "name": "multiple mitochondrial dysfunctions syndrome 1", "description": "A multiple mitochondrial dysfunctions syndrome that is characterized by weakness, respiratory failure, lack of neurologic development, lactic acidosis, and early death, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the NFU1 iron-sulfur cluster scaffold gene on chromosome 2p13.", "url": "https://disease-ontology.org/term/DOID:0080133", "evidence": [ { "id": "0080133", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080133" } ], "weight": 0.0 } ], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "P32860", "url": "https://www.uniprot.org/uniprotkb/P32860" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "P32860", "url": "https://www.uniprot.org/uniprotkb/P32860" } ], "pmid": "" }, { "name": "[4Fe-4S] cluster assembly", "id": "GO:0044572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044572", "evidence": [ { "database": "UniProtKB", "id": "P32860", "url": "https://www.uniprot.org/uniprotkb/P32860" } ], "pmid": "" } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "P32860", "url": "https://www.uniprot.org/uniprotkb/P32860" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "P32860", "url": "https://www.uniprot.org/uniprotkb/P32860" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32860", "url": "https://www.uniprot.org/uniprotkb/P32860" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P32860", "url": "https://www.uniprot.org/uniprotkb/P32860" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32860-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001523", "url": "https://www.yeastgenome.org/locus/S000001523" }, { "database": "iPTMnet", "id": "P32860", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32860" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32860-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001523", "url": "https://www.yeastgenome.org/locus/S000001523" }, { "database": "iPTMnet", "id": "P32860", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32860" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32860-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Ser248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001523", "url": "https://www.yeastgenome.org/locus/S000001523" }, { "database": "iPTMnet", "id": "P32860", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32860" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32860-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32860", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32860" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001523", "url": "https://www.yeastgenome.org/locus/S000001523" } ] } ] }, { "uniprot_canonical_ac": "P32860-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32860", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32860" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001523", "url": "https://www.yeastgenome.org/locus/S000001523" } ] } ] }, { "uniprot_canonical_ac": "P32860-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Gly194", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "C", "comment": "Dominant negative mutant; cells show a severe synthetic sick phenotype on glycerol/lactate medium.", "evidence": [ { "database": "UniProtKB", "id": "P32860", "url": "https://www.uniprot.org/uniprotkb/P32860" }, { "database": "PubMed", "id": "27532773", "url": "https://glygen.org/publication/PubMed/27532773" } ] } ] } ], "record_id": "P32860-1" }, { "uniprot_canonical_ac": "P32861-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 499, "chemical_mass": 55988.0, "gene_names": "UGP1;UGP1;YKL248", "protein_name": "UTP--glucose-1-phosphate uridylyltransferase", "disease": [ { "disease_id": "DOID:0112218", "name": "developmental and epileptic encephalopathy 83", "description": "A developmental and epileptic encephalopathy characterized by onset in the first days or months of life of frequent, usually refractory, seizures and profoundly impaired development that has_material_basis_in homozygous or compound heterozygous mutation in the UGP2 gene on chromosome 2p15.", "url": "https://disease-ontology.org/term/DOID:0112218", "evidence": [ { "id": "0112218", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112218" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" }, { "name": "UTP:glucose-1-phosphate uridylyltransferase activity", "id": "GO:0003983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003983", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" }, { "name": "uridylyltransferase activity", "id": "GO:0070569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070569", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" } ], "biological_process": [ { "name": "glycogen metabolic process", "id": "GO:0005977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" }, { "name": "glycogen biosynthetic process", "id": "GO:0005978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005978", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" }, { "name": "UDP-alpha-D-glucose metabolic process", "id": "GO:0006011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006011", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" }, { "name": "trehalose biosynthetic process", "id": "GO:0005992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005992", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" }, { "name": "(1->6)-beta-D-glucan biosynthetic process", "id": "GO:0006078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006078", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32861-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Ser286", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 286, "start_aa": "Ser", "end_pos": 286, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser286", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32861", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32861" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Thr115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "12372297", "url": "https://glygen.org/publication/PubMed/12372297" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17531808", "url": "https://glygen.org/publication/PubMed/17531808" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Thr12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Tyr13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Thr349", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Thr389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "391", "end_pos": "391", "site_lbl": "Ser391", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "413", "end_pos": "413", "site_lbl": "Ser413", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "425", "end_pos": "425", "site_lbl": "Ser425", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Ser431", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32861", "url": "https://www.uniprot.org/uniprotkb/P32861" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32861-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Thr9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32861", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32861" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001518", "url": "https://www.yeastgenome.org/locus/S000001518" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P32861-1" }, { "uniprot_canonical_ac": "P32862-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1170, "chemical_mass": 128240.0, "gene_names": "RGT1;RGT1;YKL251", "protein_name": "Glucose transport transcription regulator RGT1", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" }, { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32862-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Ser410", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 410, "start_aa": "Ser", "end_pos": 410, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser410", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32862", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32862" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "414", "end_pos": "414", "site_lbl": "Ser414", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 414, "start_aa": "Ser", "end_pos": 414, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser414", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32862", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32862" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "418", "end_pos": "418", "site_lbl": "Ser418", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 418, "start_aa": "Ser", "end_pos": 418, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser418", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32862", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32862" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "1098", "end_pos": "1098", "site_lbl": "Ser1098", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "1129", "end_pos": "1129", "site_lbl": "Thr1129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "1130", "end_pos": "1130", "site_lbl": "Ser1130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "1132", "end_pos": "1132", "site_lbl": "Thr1132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "1135", "end_pos": "1135", "site_lbl": "Thr1135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "1136", "end_pos": "1136", "site_lbl": "Thr1136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "16844691", "url": "https://glygen.org/publication/PubMed/16844691" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "16844691", "url": "https://glygen.org/publication/PubMed/16844691" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Ser208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Thr20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Thr214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Tyr223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Thr225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Thr232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Thr247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Ser283", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "16844691", "url": "https://glygen.org/publication/PubMed/16844691" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32862", "url": "https://www.uniprot.org/uniprotkb/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "16844691", "url": "https://glygen.org/publication/PubMed/16844691" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Ser287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "366", "end_pos": "366", "site_lbl": "Ser366", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Thr416", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "465", "end_pos": "465", "site_lbl": "Ser465", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Thr469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Ser492", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "493", "end_pos": "493", "site_lbl": "Ser493", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Ser495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Ser599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Ser601", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "625", "end_pos": "625", "site_lbl": "Ser625", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "744", "end_pos": "744", "site_lbl": "Ser744", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "962", "end_pos": "962", "site_lbl": "Ser962", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001521", "url": "https://www.yeastgenome.org/locus/S000001521" }, { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32862-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32862", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32862" }, { "database": "PubMed", "id": "16844691", "url": "https://glygen.org/publication/PubMed/16844691" } ] } ] } ], "record_id": "P32862-1" }, { "uniprot_canonical_ac": "P32864-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 603, "chemical_mass": 67374.0, "gene_names": "MRS6;MRS6;MSI4", "protein_name": "Rab proteins geranylgeranyltransferase component A", "disease": [ { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:9821", "name": "choroideremia", "description": "", "url": "https://disease-ontology.org/term/DOID:9821", "evidence": [ { "id": "9821", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9821" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" }, { "name": "GDP-dissociation inhibitor activity", "id": "GO:0005092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005092", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" }, { "name": "Rab-protein geranylgeranyltransferase complex", "id": "GO:0005968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005968", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" }, { "name": "protein geranylgeranylation", "id": "GO:0018344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018344", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32864-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005897", "url": "https://www.yeastgenome.org/locus/S000005897" }, { "database": "iPTMnet", "id": "P32864", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32864" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32864-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005897", "url": "https://www.yeastgenome.org/locus/S000005897" }, { "database": "iPTMnet", "id": "P32864", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32864" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32864-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005897", "url": "https://www.yeastgenome.org/locus/S000005897" }, { "database": "iPTMnet", "id": "P32864", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32864" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32864-1", "start_pos": "443", "end_pos": "443", "site_lbl": "Ser443", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005897", "url": "https://www.yeastgenome.org/locus/S000005897" }, { "database": "iPTMnet", "id": "P32864", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32864" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32864-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Thr460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32864", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32864" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000005897", "url": "https://www.yeastgenome.org/locus/S000005897" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32864-1", "start_pos": "464", "end_pos": "464", "site_lbl": "Ser464", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32864", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32864" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005897", "url": "https://www.yeastgenome.org/locus/S000005897" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32864-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Ser470", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32864", "url": "https://www.uniprot.org/uniprotkb/P32864" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P32864", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32864" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005897", "url": "https://www.yeastgenome.org/locus/S000005897" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32864-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Ser553", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005897", "url": "https://www.yeastgenome.org/locus/S000005897" }, { "database": "iPTMnet", "id": "P32864", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32864" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32864-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005897", "url": "https://www.yeastgenome.org/locus/S000005897" }, { "database": "iPTMnet", "id": "P32864", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32864" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32864-1" }, { "uniprot_canonical_ac": "P32873-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1128, "chemical_mass": 124913.0, "gene_names": "BEM3;BEM3;LPH12C", "protein_name": "GTPase-activating protein BEM3", "disease": [], "cellular_component": [ { "name": "cell tip", "id": "GO:0051286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051286", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "site of polarized growth", "id": "GO:0030427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030427", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" }, { "name": "septin ring organization", "id": "GO:0031106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031106", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32873-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Thr151", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 201, "start_aa": "Ser", "end_pos": 201, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser201", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 206, "start_aa": "Ser", "end_pos": 206, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser206", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Ser210", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 210, "start_aa": "Ser", "end_pos": 210, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser210", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Thr212", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 212, "start_aa": "Thr", "end_pos": 212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr212", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Thr214", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 214, "start_aa": "Thr", "end_pos": 214, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr214", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Thr215", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 216, "start_aa": "Ser", "end_pos": 216, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser216", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 259, "start_aa": "Ser", "end_pos": 259, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser259", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Ser261", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 261, "start_aa": "Ser", "end_pos": 261, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser261", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "22118465", "url": "https://glygen.org/publication/PubMed/22118465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Ser270", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 270, "start_aa": "Ser", "end_pos": 270, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser270", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Ser288", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 288, "start_aa": "Ser", "end_pos": 288, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser288", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Ser289", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 289, "start_aa": "Ser", "end_pos": 289, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser289", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Ser302", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 302, "start_aa": "Ser", "end_pos": 302, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser302", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32873", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32873" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17914457", "url": "https://glygen.org/publication/PubMed/17914457" } ] }, { "kinase_uniprot_canonical_ac": "P20438-1", "kinase_gene_name": "CLN2", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17914457", "url": "https://glygen.org/publication/PubMed/17914457" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Ser222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17914457", "url": "https://glygen.org/publication/PubMed/17914457" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "P20438-1", "kinase_gene_name": "CLN2", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17914457", "url": "https://glygen.org/publication/PubMed/17914457" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Ser227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Ser237", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Ser254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17914457", "url": "https://glygen.org/publication/PubMed/17914457" } ] }, { "kinase_uniprot_canonical_ac": "P20438-1", "kinase_gene_name": "CLN2", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17914457", "url": "https://glygen.org/publication/PubMed/17914457" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32873", "url": "https://www.uniprot.org/uniprotkb/P32873" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Thr260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "22118465", "url": "https://glygen.org/publication/PubMed/22118465" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Tyr295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Thr299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Ser308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Ser309", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Ser324", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Ser327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Ser341", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Thr374", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Thr388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "391", "end_pos": "391", "site_lbl": "Ser391", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "422", "end_pos": "422", "site_lbl": "Ser422", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "423", "end_pos": "423", "site_lbl": "Ser423", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Thr466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Ser487", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Ser488", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "491", "end_pos": "491", "site_lbl": "Thr491", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Ser494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Ser498", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "583", "end_pos": "583", "site_lbl": "Thr583", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Ser585", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17914457", "url": "https://glygen.org/publication/PubMed/17914457" } ] }, { "kinase_uniprot_canonical_ac": "P20438-1", "kinase_gene_name": "CLN2", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17914457", "url": "https://glygen.org/publication/PubMed/17914457" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "759", "end_pos": "759", "site_lbl": "Ser759", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "764", "end_pos": "764", "site_lbl": "Ser764", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "767", "end_pos": "767", "site_lbl": "Thr767", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "868", "end_pos": "868", "site_lbl": "Ser868", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "870", "end_pos": "870", "site_lbl": "Ser870", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "873", "end_pos": "873", "site_lbl": "Ser873", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006036", "url": "https://www.yeastgenome.org/locus/S000006036" }, { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32873-1", "start_pos": "880", "end_pos": "880", "site_lbl": "Ser880", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17914457", "url": "https://glygen.org/publication/PubMed/17914457" } ] }, { "kinase_uniprot_canonical_ac": "P20438-1", "kinase_gene_name": "CLN2", "evidence": [ { "database": "iPTMnet", "id": "P32873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32873" }, { "database": "PubMed", "id": "17914457", "url": "https://glygen.org/publication/PubMed/17914457" } ] } ] } ], "record_id": "P32873-1" }, { "uniprot_canonical_ac": "P32874-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32874", "url": "https://www.uniprot.org/uniprotkb/P32874" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 2273, "chemical_mass": 259163.0, "gene_names": "HFA1;HFA1;YM8261.01C;YM8325.08C", "protein_name": "Acetyl-CoA carboxylase, mitochondrial", "disease": [ { "disease_id": "DOID:0060404", "name": "chromosome 17q12 deletion syndrome", "description": "A chromosomal deletion syndrome that has_material_basis_in a chromosome 17q12 deletion and that is characterized by renal cystic disease, maturity onset diabetes of the young type 5, cognitive impairment, developmental delay (particularly of speech), autistic traits and autism spectrum disorder.", "url": "https://disease-ontology.org/term/DOID:0060404", "evidence": [ { "id": "0060404", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060404" } ], "weight": 0.0 }, { "disease_id": "DOID:0080000", "name": "muscular disease", "description": "A musculoskeletal system disease that affects the muscles.", "url": "https://disease-ontology.org/term/DOID:0080000", "evidence": [ { "id": "0080000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080000" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0080547", "name": "metabolic dysfunction-associated steatohepatitis", "description": "A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.", "url": "https://disease-ontology.org/term/DOID:0080547", "evidence": [ { "id": "0080547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080547" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32874", "url": "https://www.uniprot.org/uniprotkb/P32874" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32874", "url": "https://www.uniprot.org/uniprotkb/P32874" } ], "pmid": "" }, { "name": "acetyl-CoA carboxylase activity", "id": "GO:0003989", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003989", "evidence": [ { "database": "UniProtKB", "id": "P32874", "url": "https://www.uniprot.org/uniprotkb/P32874" } ], "pmid": "" }, { "name": "biotin carboxylase activity", "id": "GO:0004075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004075", "evidence": [ { "database": "UniProtKB", "id": "P32874", "url": "https://www.uniprot.org/uniprotkb/P32874" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32874", "url": "https://www.uniprot.org/uniprotkb/P32874" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32874", "url": "https://www.uniprot.org/uniprotkb/P32874" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "P32874", "url": "https://www.uniprot.org/uniprotkb/P32874" } ], "pmid": "" }, { "name": "malonyl-CoA biosynthetic process", "id": "GO:2001295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001295", "evidence": [ { "database": "UniProtKB", "id": "P32874", "url": "https://www.uniprot.org/uniprotkb/P32874" } ], "pmid": "" }, { "name": "long-chain fatty acid biosynthetic process", "id": "GO:0042759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042759", "evidence": [ { "database": "UniProtKB", "id": "P32874", "url": "https://www.uniprot.org/uniprotkb/P32874" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32874-1", "start_pos": "1390", "end_pos": "1390", "site_lbl": "Ser1390", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1390, "start_aa": "Ser", "end_pos": 1390, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1390", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32874", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32874" } ] } ] }, { "uniprot_canonical_ac": "P32874-1", "start_pos": "776", "end_pos": "776", "site_lbl": "Thr776", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 776, "start_aa": "Thr", "end_pos": 776, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr776", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32874-1", "start_pos": "1358", "end_pos": "1358", "site_lbl": "Ser1358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004820", "url": "https://www.yeastgenome.org/locus/S000004820" }, { "database": "iPTMnet", "id": "P32874", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32874" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32874-1", "start_pos": "1361", "end_pos": "1361", "site_lbl": "Thr1361", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004820", "url": "https://www.yeastgenome.org/locus/S000004820" }, { "database": "iPTMnet", "id": "P32874", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32874" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32874-1", "start_pos": "1362", "end_pos": "1362", "site_lbl": "Tyr1362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004820", "url": "https://www.yeastgenome.org/locus/S000004820" }, { "database": "iPTMnet", "id": "P32874", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32874" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32874-1", "start_pos": "1364", "end_pos": "1364", "site_lbl": "Ser1364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004820", "url": "https://www.yeastgenome.org/locus/S000004820" }, { "database": "iPTMnet", "id": "P32874", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32874" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32874-1", "start_pos": "1365", "end_pos": "1365", "site_lbl": "Ser1365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004820", "url": "https://www.yeastgenome.org/locus/S000004820" }, { "database": "iPTMnet", "id": "P32874", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32874" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32874-1" }, { "uniprot_canonical_ac": "P32891-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32891", "url": "https://www.uniprot.org/uniprotkb/P32891" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 587, "chemical_mass": 65293.0, "gene_names": "DLD1;DLD1;DLD", "protein_name": "D-lactate dehydrogenase [cytochrome] 1, mitochondrial", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32891", "url": "https://www.uniprot.org/uniprotkb/P32891" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P32891", "url": "https://www.uniprot.org/uniprotkb/P32891" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P32891", "url": "https://www.uniprot.org/uniprotkb/P32891" } ], "pmid": "" } ], "molecular_function": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "P32891", "url": "https://www.uniprot.org/uniprotkb/P32891" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "P32891", "url": "https://www.uniprot.org/uniprotkb/P32891" } ], "pmid": "" }, { "name": "D-lactate dehydrogenase (cytochrome) activity", "id": "GO:0004458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004458", "evidence": [ { "database": "UniProtKB", "id": "P32891", "url": "https://www.uniprot.org/uniprotkb/P32891" } ], "pmid": "" }, { "name": "D-lactate dehydrogenase (NAD+) activity", "id": "GO:0008720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008720", "evidence": [ { "database": "UniProtKB", "id": "P32891", "url": "https://www.uniprot.org/uniprotkb/P32891" } ], "pmid": "" } ], "biological_process": [ { "name": "lactate catabolic process", "id": "GO:1903457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903457", "evidence": [ { "database": "UniProtKB", "id": "P32891", "url": "https://www.uniprot.org/uniprotkb/P32891" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32891-1" }, { "uniprot_canonical_ac": "P32892-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 752, "chemical_mass": 84843.0, "gene_names": "DRS1;DRS1;L1345", "protein_name": "ATP-dependent RNA helicase DRS1", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32892-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Ser128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003931", "url": "https://www.yeastgenome.org/locus/S000003931" }, { "database": "iPTMnet", "id": "P32892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Ser208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32892" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003931", "url": "https://www.yeastgenome.org/locus/S000003931" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003931", "url": "https://www.yeastgenome.org/locus/S000003931" }, { "database": "iPTMnet", "id": "P32892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32892" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003931", "url": "https://www.yeastgenome.org/locus/S000003931" }, { "database": "iPTMnet", "id": "P32892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32892" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Met191", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "T", "comment": "No growth at 13 degrees Celsius; when associated with Q-431 and G-472.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Ala260", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "V", "comment": "No growth at 13 degrees Celsius; when associated with P-564.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ala273", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "T", "comment": "No growth at 13 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Pro288", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "No growth at 13 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Glu291", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "V", "comment": "No growth at 13 degrees Celsius; when associated with G-637.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Val305", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "D", "comment": "No growth at 13 degrees Celsius; when associated with V-306.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ile306", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "V", "comment": "No growth at 13 degrees Celsius; when associated with D-305.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "414", "end_pos": "414", "site_lbl": "Leu414", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "No growth at 13 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Leu429", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "No growth at 13 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Leu431", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "Q", "comment": "No growth at 13 degrees Celsius; when associated with T-191 and G-472.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Arg472", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "G", "comment": "No growth at 13 degrees Celsius; when associated with T-191 and Q-431.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "509", "end_pos": "509", "site_lbl": "Leu509", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "No growth at 13 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "563", "end_pos": "563", "site_lbl": "Tyr563", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "C", "comment": "No growth at 13 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Leu564", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "No growth at 13 degrees Celsius; when associated with V-260.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] }, { "uniprot_canonical_ac": "P32892-1", "start_pos": "637", "end_pos": "637", "site_lbl": "Asp637", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "G", "comment": "No growth at 13 degrees Celsius; when associated with V-291.", "evidence": [ { "database": "UniProtKB", "id": "P32892", "url": "https://www.uniprot.org/uniprotkb/P32892" }, { "database": "PubMed", "id": "11911362", "url": "https://glygen.org/publication/PubMed/11911362" } ] } ] } ], "record_id": "P32892-1" }, { "uniprot_canonical_ac": "P32893-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 560, "chemical_mass": 63368.0, "gene_names": "TRS65;KRE11;TRS65", "protein_name": "Trafficking protein particle complex II-specific subunit 65", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" } ], "pmid": "" }, { "name": "TRAPPII protein complex", "id": "GO:1990071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990071", "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" } ], "pmid": "" } ], "biological_process": [ { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" } ], "pmid": "" }, { "name": "beta-glucan biosynthetic process", "id": "GO:0051274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051274", "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32893-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Ser389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Ser398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32893", "url": "https://www.uniprot.org/uniprotkb/P32893" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Thr399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Thr400", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Ser401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32893-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Ser479", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003398", "url": "https://www.yeastgenome.org/locus/S000003398" }, { "database": "iPTMnet", "id": "P32893", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32893" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32893-1" }, { "uniprot_canonical_ac": "P32895-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 427, "chemical_mass": 47047.0, "gene_names": "PRS1;PPS1;PRP1;PRPS1;PRPS;PRS1", "protein_name": "Ribose-phosphate pyrophosphokinase 1", "disease": [ { "disease_id": "DOID:0050566", "name": "X-linked nonsyndromic deafness", "description": "A nonsyndromic deafness characterized by an X-linked inheritance mode.", "url": "https://disease-ontology.org/term/DOID:0050566", "evidence": [ { "id": "0050566", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050566" } ], "weight": 0.0 }, { "disease_id": "DOID:0050647", "name": "Arts syndrome", "description": "An X-linked disease that is characterized by profound congenital sensorineural hearing impairment, early-onset hypotonia, delayed motor development, mild to moderate intellectual disability, ataxia, and increased risk of infection and has_material_basis_in mutations of the PRPS1 gene.", "url": "https://disease-ontology.org/term/DOID:0050647", "evidence": [ { "id": "0050647", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050647" } ], "weight": 0.0 }, { "disease_id": "DOID:0110210", "name": "Charcot-Marie-Tooth disease X-linked recessive 5", "description": "A Charcot-Marie-Tooth disease X-linked that has_material_basis_in loss-of-function mutation in the PRPS1 gene on chromosome Xq22.", "url": "https://disease-ontology.org/term/DOID:0110210", "evidence": [ { "id": "0110210", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110210" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ribose phosphate diphosphokinase complex", "id": "GO:0002189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002189", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "pmid": "" }, { "name": "ribose phosphate diphosphokinase activity", "id": "GO:0004749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004749", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "pmid": "" } ], "biological_process": [ { "name": "ribonucleoside monophosphate biosynthetic process", "id": "GO:0009156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009156", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "pmid": "" }, { "name": "5-phosphoribose 1-diphosphate biosynthetic process", "id": "GO:0006015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006015", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "pmid": "" }, { "name": "purine nucleotide biosynthetic process", "id": "GO:0006164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006164", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32895-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Thr179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" } ] } ] }, { "uniprot_canonical_ac": "P32895-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" } ] } ] }, { "uniprot_canonical_ac": "P32895-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Ser199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32895-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" }, { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32895-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32895-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Ser271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" }, { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32895-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" }, { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32895-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Ser283", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" }, { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32895-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Thr289", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" }, { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32895-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Tyr290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" }, { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32895-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Ser295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32895", "url": "https://www.uniprot.org/uniprotkb/P32895" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32895" }, { "database": "SGD", "id": "S000001664", "url": "https://www.yeastgenome.org/locus/S000001664" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32895-1" }, { "uniprot_canonical_ac": "P32897-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32897", "url": "https://www.uniprot.org/uniprotkb/P32897" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 222, "chemical_mass": 23244.0, "gene_names": "TIM23;MAS6;MIM23;MPI3;N3180;TIM23", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM23", "disease": [ { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32897", "url": "https://www.uniprot.org/uniprotkb/P32897" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P32897", "url": "https://www.uniprot.org/uniprotkb/P32897" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P32897", "url": "https://www.uniprot.org/uniprotkb/P32897" } ], "pmid": "" }, { "name": "TIM23 mitochondrial import inner membrane translocase complex", "id": "GO:0005744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005744", "evidence": [ { "database": "UniProtKB", "id": "P32897", "url": "https://www.uniprot.org/uniprotkb/P32897" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P32897", "url": "https://www.uniprot.org/uniprotkb/P32897" } ], "pmid": "" }, { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "P32897", "url": "https://www.uniprot.org/uniprotkb/P32897" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "P32897", "url": "https://www.uniprot.org/uniprotkb/P32897" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "P32897", "url": "https://www.uniprot.org/uniprotkb/P32897" } ], "pmid": "" }, { "name": "mitochondrion targeting sequence binding", "id": "GO:0030943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030943", "evidence": [ { "database": "UniProtKB", "id": "P32897", "url": "https://www.uniprot.org/uniprotkb/P32897" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32897-1" }, { "uniprot_canonical_ac": "P32898-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 989, "chemical_mass": 112180.0, "gene_names": "CYM1;CYM1;D9461.18;MOP112", "protein_name": "Presequence protease, mitochondrial", "disease": [ { "disease_id": "DOID:0050951", "name": "hereditary ataxia", "description": "A neurodegenerative disease that is characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements.", "url": "https://disease-ontology.org/term/DOID:0050951", "evidence": [ { "id": "0050951", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050951" } ], "weight": 0.0 }, { "disease_id": "DOID:0070411", "name": "autosomal recessive spinocerebellar ataxia 30", "description": "An autosomal recessive cerebellar ataxia characterized by childhood-onset global developmental delay with variably impaired intellectual development, motor dysfunction, and cerebellar ataxia that has_material_basis_in homozygous mutation in the PITRM1 gene on chromosome 10p15.", "url": "https://disease-ontology.org/term/DOID:0070411", "evidence": [ { "id": "0070411", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070411" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:9277", "name": "primary cerebellar degeneration", "description": "", "url": "https://disease-ontology.org/term/DOID:9277", "evidence": [ { "id": "9277", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9277" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" } ], "pmid": "" }, { "name": "ATP-dependent peptidase activity", "id": "GO:0004176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004176", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" } ], "pmid": "" }, { "name": "mitochondrial protein processing", "id": "GO:0034982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034982", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32898-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Thr358", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 358, "start_aa": "Thr", "end_pos": 358, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr358", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32898-1", "start_pos": "645", "end_pos": "645", "site_lbl": "Ser645", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002838", "url": "https://www.yeastgenome.org/locus/S000002838" }, { "database": "iPTMnet", "id": "P32898", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32898" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32898-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Thr647", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002838", "url": "https://www.yeastgenome.org/locus/S000002838" }, { "database": "iPTMnet", "id": "P32898", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32898" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32898-1", "start_pos": "920", "end_pos": "920", "site_lbl": "Ser920", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32898", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32898" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000002838", "url": "https://www.yeastgenome.org/locus/S000002838" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32898-1", "start_pos": "84", "end_pos": "84", "site_lbl": "His84", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" }, { "database": "PubMed", "id": "15772085", "url": "https://glygen.org/publication/PubMed/15772085" }, { "database": "PubMed", "id": "25176146", "url": "https://glygen.org/publication/PubMed/25176146" } ] } ] }, { "uniprot_canonical_ac": "P32898-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Glu87", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" }, { "database": "PubMed", "id": "15772085", "url": "https://glygen.org/publication/PubMed/15772085" }, { "database": "PubMed", "id": "25176146", "url": "https://glygen.org/publication/PubMed/25176146" } ] } ] }, { "uniprot_canonical_ac": "P32898-1", "start_pos": "88", "end_pos": "88", "site_lbl": "His88", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P32898", "url": "https://www.uniprot.org/uniprotkb/P32898" }, { "database": "PubMed", "id": "15772085", "url": "https://glygen.org/publication/PubMed/15772085" }, { "database": "PubMed", "id": "25176146", "url": "https://glygen.org/publication/PubMed/25176146" } ] } ] } ], "record_id": "P32898-1" }, { "uniprot_canonical_ac": "P32899-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 183, "chemical_mass": 21885.0, "gene_names": "IMP3;IMP3", "protein_name": "U3 small nucleolar ribonucleoprotein protein IMP3", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" }, { "name": "Mpp10 complex", "id": "GO:0034457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034457", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" } ], "molecular_function": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" }, { "name": "RNA folding chaperone", "id": "GO:0140691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140691", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "P32899", "url": "https://www.uniprot.org/uniprotkb/P32899" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P32899-1" }, { "uniprot_canonical_ac": "P32900-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 734, "chemical_mass": 81849.0, "gene_names": "SKG6;SKG6", "protein_name": "Protein SKG6", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of mitotic cytokinesis", "id": "GO:1902413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902413", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32900-1", "start_pos": "558", "end_pos": "558", "site_lbl": "Thr558", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 558, "start_aa": "Thr", "end_pos": 558, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr558", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "639", "end_pos": "639", "site_lbl": "Ser639", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 639, "start_aa": "Ser", "end_pos": 639, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser639", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32900", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32900" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "643", "end_pos": "643", "site_lbl": "Thr643", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 643, "start_aa": "Thr", "end_pos": 643, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr643", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32900", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32900" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 646, "start_aa": "Ser", "end_pos": 646, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser646", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32900", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32900" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "653", "end_pos": "653", "site_lbl": "Ser653", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 653, "start_aa": "Ser", "end_pos": 653, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser653", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32900", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32900" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "659", "end_pos": "659", "site_lbl": "Ser659", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 659, "start_aa": "Ser", "end_pos": 659, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser659", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32900", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32900" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Tyr133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Thr145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Tyr163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Thr169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Ser215", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Thr221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Ser222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Thr232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Ser243", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Ser248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Ser251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Ser262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Ser310", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Thr313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Ser346", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Ser395", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "411", "end_pos": "411", "site_lbl": "Ser411", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "593", "end_pos": "593", "site_lbl": "Thr593", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "606", "end_pos": "606", "site_lbl": "Ser606", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "662", "end_pos": "662", "site_lbl": "Ser662", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "664", "end_pos": "664", "site_lbl": "Ser664", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "666", "end_pos": "666", "site_lbl": "Thr666", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "672", "end_pos": "672", "site_lbl": "Ser672", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "694", "end_pos": "694", "site_lbl": "Ser694", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "707", "end_pos": "707", "site_lbl": "Ser707", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Ser715", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32900-1", "start_pos": "717", "end_pos": "717", "site_lbl": "Ser717", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32900", "url": "https://www.uniprot.org/uniprotkb/P32900" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32900", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32900" }, { "database": "SGD", "id": "S000001192", "url": "https://www.yeastgenome.org/locus/S000001192" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32900-1" }, { "uniprot_canonical_ac": "P32901-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 601, "chemical_mass": 68044.0, "gene_names": "PTR2;PTR2;YKR413", "protein_name": "Peptide transporter PTR2", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" }, { "name": "peptide transport", "id": "GO:0015833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015833", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" }, { "name": "dipeptide import across plasma membrane", "id": "GO:0140206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140206", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" }, { "name": "dipeptide transport", "id": "GO:0042938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042938", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" }, { "name": "tripeptide transport", "id": "GO:0042939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042939", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" } ], "molecular_function": [ { "name": "tripeptide transmembrane transporter activity", "id": "GO:0042937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042937", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" }, { "name": "peptide transmembrane transporter activity", "id": "GO:1904680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904680", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" }, { "name": "dipeptide transmembrane transporter activity", "id": "GO:0071916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071916", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32901-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Thr140", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 140, "start_aa": "Thr", "end_pos": 140, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr140", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Thr32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Tyr37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Thr46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Tyr49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Ser54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "594", "end_pos": "594", "site_lbl": "Ser594", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32901", "url": "https://www.uniprot.org/uniprotkb/P32901" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "597", "end_pos": "597", "site_lbl": "Ser597", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "598", "end_pos": "598", "site_lbl": "Thr598", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Thr599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Tyr601", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Thr64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32901-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32901", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32901" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001801", "url": "https://www.yeastgenome.org/locus/S000001801" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32901-1" }, { "uniprot_canonical_ac": "P32905-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 252, "chemical_mass": 28024.0, "gene_names": "RPS0A;NAB1A;NAB1;RPS0A;YST1", "protein_name": "Small ribosomal subunit protein uS2A", "disease": [ { "disease_id": "DOID:0110074", "name": "arrhythmogenic right ventricular dysplasia 5", "description": "An arrhythmogenic right ventricular dysplasia that has_material_basis_in heterozygous mutation in the TMEM43 gene on chromosome 3p25.", "url": "https://disease-ontology.org/term/DOID:0110074", "evidence": [ { "id": "0110074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110074" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:1339", "name": "Diamond-Blackfan anemia", "description": "A pure red-cell aplasia that is characterized by anemia (low red blood cell counts) with decreased erythroid progenitors in the bone marrow and has_material_basis_insufficient levels of red blood cells due to bone marrow dysfunction.", "url": "https://disease-ontology.org/term/DOID:1339", "evidence": [ { "id": "1339", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1339" } ], "weight": 0.0 }, { "disease_id": "DOID:9778", "name": "irritable bowel syndrome", "description": "An intestinal disease that is characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause.", "url": "https://disease-ontology.org/term/DOID:9778", "evidence": [ { "id": "9778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9778" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000461", "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P32905", "url": "https://www.uniprot.org/uniprotkb/P32905" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32905-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32905", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32905" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003446", "url": "https://www.yeastgenome.org/locus/S000003446" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32905-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32905", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32905" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003446", "url": "https://www.yeastgenome.org/locus/S000003446" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32905-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32905", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32905" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003446", "url": "https://www.yeastgenome.org/locus/S000003446" } ] } ] }, { "uniprot_canonical_ac": "P32905-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Thr219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003446", "url": "https://www.yeastgenome.org/locus/S000003446" }, { "database": "iPTMnet", "id": "P32905", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32905" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32905-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Thr220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003446", "url": "https://www.yeastgenome.org/locus/S000003446" }, { "database": "iPTMnet", "id": "P32905", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32905" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32905-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003446", "url": "https://www.yeastgenome.org/locus/S000003446" }, { "database": "iPTMnet", "id": "P32905", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32905" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32905-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Thr80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003446", "url": "https://www.yeastgenome.org/locus/S000003446" }, { "database": "iPTMnet", "id": "P32905", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32905" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32905-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Thr96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003446", "url": "https://www.yeastgenome.org/locus/S000003446" }, { "database": "iPTMnet", "id": "P32905", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32905" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P32905-1" }, { "uniprot_canonical_ac": "P32911-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 108, "chemical_mass": 12312.0, "gene_names": "SUI1;MOF2;N0905;RFR1;SUI1", "protein_name": "Eukaryotic translation initiation factor eIF-1", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "pmid": "" }, { "name": "ribosomal small subunit binding", "id": "GO:0043024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043024", "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "pmid": "" }, { "name": "translation initiation factor binding", "id": "GO:0031369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369", "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "pmid": "" }, { "name": "maintenance of translational fidelity", "id": "GO:1990145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990145", "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "pmid": "" }, { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "pmid": "" }, { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "pmid": "" }, { "name": "multi-eIF complex", "id": "GO:0043614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043614", "evidence": [ { "database": "UniProtKB", "id": "P32911", "url": "https://www.uniprot.org/uniprotkb/P32911" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32911-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Thr15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32911" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005188", "url": "https://www.yeastgenome.org/locus/S000005188" }, { "database": "PubMed", "id": "32027465", "url": "https://glygen.org/publication/PubMed/32027465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32911-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005188", "url": "https://www.yeastgenome.org/locus/S000005188" }, { "database": "iPTMnet", "id": "P32911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32911" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P32911-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32911" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005188", "url": "https://www.yeastgenome.org/locus/S000005188" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32911-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Thr38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005188", "url": "https://www.yeastgenome.org/locus/S000005188" }, { "database": "iPTMnet", "id": "P32911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32911" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32911-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Thr40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005188", "url": "https://www.yeastgenome.org/locus/S000005188" }, { "database": "iPTMnet", "id": "P32911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32911" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32911-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005188", "url": "https://www.yeastgenome.org/locus/S000005188" }, { "database": "iPTMnet", "id": "P32911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32911" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32911-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005188", "url": "https://www.yeastgenome.org/locus/S000005188" }, { "database": "iPTMnet", "id": "P32911", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32911" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P32911-1" }, { "uniprot_canonical_ac": "P32913-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 551, "chemical_mass": 63204.0, "gene_names": "VPS17;O3314;PEP21;VPS17;VPT3;YOR3314W", "protein_name": "Vacuolar protein sorting-associated protein 17", "disease": [], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" } ], "pmid": "" }, { "name": "retromer, tubulation complex", "id": "GO:0030905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030905", "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32913-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Ser481", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 481, "start_aa": "Ser", "end_pos": 481, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser481", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32913", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32913" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "485", "end_pos": "485", "site_lbl": "Ser485", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 485, "start_aa": "Ser", "end_pos": 485, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser485", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32913", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32913" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Ser488", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 488, "start_aa": "Ser", "end_pos": 488, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser488", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P32913", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P32913" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" }, { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Ser100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" }, { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" }, { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Ser417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Ser504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" }, { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "514", "end_pos": "514", "site_lbl": "Thr514", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Thr522", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "527", "end_pos": "527", "site_lbl": "Tyr527", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Ser529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "532", "end_pos": "532", "site_lbl": "Ser532", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "534", "end_pos": "534", "site_lbl": "Thr534", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "535", "end_pos": "535", "site_lbl": "Thr535", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "536", "end_pos": "536", "site_lbl": "Ser536", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Ser544", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P32913", "url": "https://www.uniprot.org/uniprotkb/P32913" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32913-1", "start_pos": "549", "end_pos": "549", "site_lbl": "Ser549", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005658", "url": "https://www.yeastgenome.org/locus/S000005658" }, { "database": "iPTMnet", "id": "P32913", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32913" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P32913-1" }, { "uniprot_canonical_ac": "P32939-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 208, "chemical_mass": 23043.0, "gene_names": "YPT7;AST4;VAM4;YM8270.02;YPT7", "protein_name": "Ypt/Rab-type GTPase YPT7", "disease": [ { "disease_id": "DOID:0050539", "name": "Charcot-Marie-Tooth disease type 2", "description": "A Charcot-Marie-Tooth disease characterized by abnormalities in the axon of the peripheral nerve cell.", "url": "https://disease-ontology.org/term/DOID:0050539", "evidence": [ { "id": "0050539", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050539" } ], "weight": 0.0 }, { "disease_id": "DOID:0110159", "name": "Charcot-Marie-Tooth disease type 2B", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in heterozygous mutation in the RAB7 gene on chromosome 3q21.", "url": "https://disease-ontology.org/term/DOID:0110159", "evidence": [ { "id": "0110159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110159" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "vacuole-mitochondrion membrane contact site", "id": "GO:1990816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990816", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "regulation of protein-containing complex assembly", "id": "GO:0043254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043254", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "vacuole inheritance", "id": "GO:0000011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000011", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "regulation of vacuole fusion, non-autophagic", "id": "GO:0032889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032889", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" }, { "name": "protein localization to vacuole", "id": "GO:0072665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072665", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32939-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004460", "url": "https://www.yeastgenome.org/locus/S000004460" }, { "database": "iPTMnet", "id": "P32939", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32939" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32939", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32939" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004460", "url": "https://www.yeastgenome.org/locus/S000004460" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Thr157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004460", "url": "https://www.yeastgenome.org/locus/S000004460" }, { "database": "iPTMnet", "id": "P32939", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32939" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "P", "comment": "Reduced nucleotide affinity leading to increased turnover between GDP- and GTP-bound states without the need of a guanine nucleotide-exchange factor. Suppresses the zinc, caffeine and calcium sensitivity of CCZ1 mutants.", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" }, { "database": "PubMed", "id": "11590240", "url": "https://glygen.org/publication/PubMed/11590240" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004460", "url": "https://www.yeastgenome.org/locus/S000004460" }, { "database": "iPTMnet", "id": "P32939", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32939" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004460", "url": "https://www.yeastgenome.org/locus/S000004460" }, { "database": "iPTMnet", "id": "P32939", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32939" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Ser207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004460", "url": "https://www.yeastgenome.org/locus/S000004460" }, { "database": "iPTMnet", "id": "P32939", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32939" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32939", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32939" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004460", "url": "https://www.yeastgenome.org/locus/S000004460" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Lys127", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "Reduced nucleotide affinity leading to increased turnover between GDP- and GTP-bound states without the need of a guanine nucleotide-exchange factor. Suppresses the zinc, caffeine and calcium sensitivity of CCZ1 mutants.", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" }, { "database": "PubMed", "id": "11590240", "url": "https://glygen.org/publication/PubMed/11590240" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Asp129", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduced nucleotide affinity leading to increased turnover between GDP- and GTP-bound states without the need of a guanine nucleotide-exchange factor. Suppresses the zinc, caffeine and calcium sensitivity of CCZ1 mutants.", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" }, { "database": "PubMed", "id": "11590240", "url": "https://glygen.org/publication/PubMed/11590240" } ] }, { "sequence_org": "D", "sequence_mut": "G", "comment": "Reduced nucleotide affinity leading to increased turnover between GDP- and GTP-bound states without the need of a guanine nucleotide-exchange factor. Suppresses the zinc, caffeine and calcium sensitivity of CCZ1 mutants.", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" }, { "database": "PubMed", "id": "11590240", "url": "https://glygen.org/publication/PubMed/11590240" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Reduced nucleotide affinity leading to increased turnover between GDP- and GTP-bound states without the need of a guanine nucleotide-exchange factor. Suppresses the zinc, caffeine and calcium sensitivity of CCZ1 mutants.", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" }, { "database": "PubMed", "id": "11590240", "url": "https://glygen.org/publication/PubMed/11590240" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ala159", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "P", "comment": "Reduced nucleotide affinity leading to increased turnover between GDP- and GTP-bound states without the need of a guanine nucleotide-exchange factor. Suppresses the zinc, caffeine and calcium sensitivity of CCZ1 mutants.", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" }, { "database": "PubMed", "id": "11590240", "url": "https://glygen.org/publication/PubMed/11590240" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "N", "comment": "Constitutively in the GDP-bound conformation. Causes loss of function during vacuolar morphogenesis. Does not suppress the zinc, caffeine and calcium sensitivity of CCZ1 mutants.", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" }, { "database": "PubMed", "id": "11590240", "url": "https://glygen.org/publication/PubMed/11590240" } ] } ] }, { "uniprot_canonical_ac": "P32939-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Gln68", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "L", "comment": "GTP-bound stabilized constitutively active mutant. Complements the fragmented vacuolar morphology of YPT7 null mutant cells. Does not suppress the zinc, caffeine and calcium sensitivity of CCZ1 mutants.", "evidence": [ { "database": "UniProtKB", "id": "P32939", "url": "https://www.uniprot.org/uniprotkb/P32939" }, { "database": "PubMed", "id": "11590240", "url": "https://glygen.org/publication/PubMed/11590240" } ] } ] } ], "record_id": "P32939-1" }, { "uniprot_canonical_ac": "P32945-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P32945", "url": "https://www.uniprot.org/uniprotkb/P32945" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 549, "chemical_mass": 61420.0, "gene_names": "PPQ1;PPQ1;SAL6", "protein_name": "Serine/threonine-protein phosphatase PPQ", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P32945", "url": "https://www.uniprot.org/uniprotkb/P32945" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P32945", "url": "https://www.uniprot.org/uniprotkb/P32945" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "P32945", "url": "https://www.uniprot.org/uniprotkb/P32945" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "P32945", "url": "https://www.uniprot.org/uniprotkb/P32945" } ], "pmid": "" }, { "name": "negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion", "id": "GO:0090029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090029", "evidence": [ { "database": "UniProtKB", "id": "P32945", "url": "https://www.uniprot.org/uniprotkb/P32945" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P32945", "url": "https://www.uniprot.org/uniprotkb/P32945" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "P32945", "url": "https://www.uniprot.org/uniprotkb/P32945" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "P32945", "url": "https://www.uniprot.org/uniprotkb/P32945" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P32945-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Ser207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Ser208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Thr210", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" } ] } ] }, { "uniprot_canonical_ac": "P32945-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P32945", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32945" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006100", "url": "https://www.yeastgenome.org/locus/S000006100" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P32945-1" }, { "uniprot_canonical_ac": "P33296-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 250, "chemical_mass": 28383.0, "gene_names": "UBC6;DOA2;UBC6", "protein_name": "Ubiquitin-conjugating enzyme E2 6", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ], "pmid": "" } ], "biological_process": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33296-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33296" }, { "database": "SGD", "id": "S000000902", "url": "https://www.yeastgenome.org/locus/S000000902" } ] } ] }, { "uniprot_canonical_ac": "P33296-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Thr178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P33296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33296" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000902", "url": "https://www.yeastgenome.org/locus/S000000902" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33296-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Thr182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000902", "url": "https://www.yeastgenome.org/locus/S000000902" }, { "database": "iPTMnet", "id": "P33296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33296" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33296-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000902", "url": "https://www.yeastgenome.org/locus/S000000902" }, { "database": "iPTMnet", "id": "P33296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33296" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33296-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Cys87", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P33296", "url": "https://www.uniprot.org/uniprotkb/P33296" } ] } ] } ], "record_id": "P33296-1" }, { "uniprot_canonical_ac": "P33297-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 434, "chemical_mass": 48256.0, "gene_names": "RPT5;O3258;RPT5;YOR3258W;YTA1", "protein_name": "26S proteasome regulatory subunit 6A", "disease": [ { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "proteasome regulatory particle, base subcomplex", "id": "GO:0008540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008540", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "pmid": "" }, { "name": "proteasome-activating activity", "id": "GO:0036402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036402", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "pmid": "" }, { "name": "proteasome regulatory particle assembly", "id": "GO:0070682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070682", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "pmid": "" }, { "name": "positive regulation of RNA polymerase II transcription preinitiation complex assembly", "id": "GO:0045899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045899", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33297-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Thr11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33297-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Thr177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" }, { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33297-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Tyr180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33297", "url": "https://www.uniprot.org/uniprotkb/P33297" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" } ] } ] }, { "uniprot_canonical_ac": "P33297-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33297-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" }, { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33297-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" }, { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33297-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Ser356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" }, { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33297-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Thr369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" } ] } ] }, { "uniprot_canonical_ac": "P33297-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Thr370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" } ] } ] }, { "uniprot_canonical_ac": "P33297-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" }, { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33297-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33297" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005643", "url": "https://www.yeastgenome.org/locus/S000005643" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33297-1" }, { "uniprot_canonical_ac": "P33298-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 428, "chemical_mass": 47894.0, "gene_names": "RPT3;D9509.14;RPT3;YNT1;YTA2", "protein_name": "26S proteasome regulatory subunit 6B homolog", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.", "url": "https://disease-ontology.org/term/DOID:2476", "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "proteasome regulatory particle, base subcomplex", "id": "GO:0008540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008540", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" }, { "name": "proteasome-activating activity", "id": "GO:0036402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036402", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" }, { "name": "proteasome regulatory particle assembly", "id": "GO:0070682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070682", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" }, { "name": "positive regulation of RNA polymerase II transcription preinitiation complex assembly", "id": "GO:0045899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045899", "evidence": [ { "database": "UniProtKB", "id": "P33298", "url": "https://www.uniprot.org/uniprotkb/P33298" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33298-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002802", "url": "https://www.yeastgenome.org/locus/S000002802" }, { "database": "iPTMnet", "id": "P33298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33298-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002802", "url": "https://www.yeastgenome.org/locus/S000002802" }, { "database": "iPTMnet", "id": "P33298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33298-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002802", "url": "https://www.yeastgenome.org/locus/S000002802" }, { "database": "iPTMnet", "id": "P33298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33298-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Ser276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002802", "url": "https://www.yeastgenome.org/locus/S000002802" }, { "database": "iPTMnet", "id": "P33298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33298" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33298-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Thr279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002802", "url": "https://www.yeastgenome.org/locus/S000002802" }, { "database": "iPTMnet", "id": "P33298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33298" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33298-1", "start_pos": "342", "end_pos": "342", "site_lbl": "Ser342", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002802", "url": "https://www.yeastgenome.org/locus/S000002802" }, { "database": "iPTMnet", "id": "P33298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33298" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33298-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002802", "url": "https://www.yeastgenome.org/locus/S000002802" }, { "database": "iPTMnet", "id": "P33298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33298-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002802", "url": "https://www.yeastgenome.org/locus/S000002802" }, { "database": "iPTMnet", "id": "P33298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33298-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Thr8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33298" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002802", "url": "https://www.yeastgenome.org/locus/S000002802" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33298-1" }, { "uniprot_canonical_ac": "P33300-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 382, "chemical_mass": 44808.0, "gene_names": "SUR1;BCL21;CSG1;LPE15;SUR1", "protein_name": "Mannosyl phosphorylinositol ceramide synthase SUR1", "disease": [], "cellular_component": [ { "name": "mannosyltransferase complex", "id": "GO:0031501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031501", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" } ], "biological_process": [ { "name": "glycosphingolipid biosynthetic process", "id": "GO:0006688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006688", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" }, { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" }, { "name": "mannosyl-inositol phosphorylceramide metabolic process", "id": "GO:0006675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006675", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" }, { "name": "mannosyl diphosphorylinositol ceramide metabolic process", "id": "GO:0006676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006676", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" }, { "name": "mannosyl-inositol phosphorylceramide biosynthetic process", "id": "GO:0051999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051999", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" } ], "molecular_function": [ { "name": "mannosyltransferase activity", "id": "GO:0000030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000030", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" }, { "name": "inositol phosphorylceramide mannosyltransferase activity", "id": "GO:0103064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0103064", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33300-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Asn224", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "automatic_literature_mining", "site_category_dict": { "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 224, "start_aa": "Asn", "end_pos": 224, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn224", "evidence": [ { "id": "35713525", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35713525" }, { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "mining_tool": "GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "GlycoSiteMiner_1.0" } ] } ] }, { "uniprot_canonical_ac": "P33300-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Ser334", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005978", "url": "https://www.yeastgenome.org/locus/S000005978" }, { "database": "iPTMnet", "id": "P33300", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33300" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33300-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Ser349", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33300", "url": "https://www.uniprot.org/uniprotkb/P33300" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33300", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33300" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005978", "url": "https://www.yeastgenome.org/locus/S000005978" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33300-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Thr351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005978", "url": "https://www.yeastgenome.org/locus/S000005978" }, { "database": "iPTMnet", "id": "P33300", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33300" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33300-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005978", "url": "https://www.yeastgenome.org/locus/S000005978" }, { "database": "iPTMnet", "id": "P33300", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33300" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33300-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Ser376", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005978", "url": "https://www.yeastgenome.org/locus/S000005978" }, { "database": "iPTMnet", "id": "P33300", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33300" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33300-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Ser381", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005978", "url": "https://www.yeastgenome.org/locus/S000005978" }, { "database": "iPTMnet", "id": "P33300", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33300" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33300-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Ser382", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005978", "url": "https://www.yeastgenome.org/locus/S000005978" }, { "database": "iPTMnet", "id": "P33300", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33300" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P33300-1" }, { "uniprot_canonical_ac": "P33301-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 854, "chemical_mass": 96365.0, "gene_names": "XRS2;D9481.13;XRS2", "protein_name": "DNA repair protein XRS2", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "double-stranded telomeric DNA binding", "id": "GO:0003691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003691", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "G-quadruplex DNA binding", "id": "GO:0051880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051880", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "single-stranded telomeric DNA binding", "id": "GO:0043047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043047", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "Mre11 complex", "id": "GO:0030870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030870", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" } ], "biological_process": [ { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "meiotic DNA double-strand break formation", "id": "GO:0042138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042138", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "mitochondrial double-strand break repair via homologous recombination", "id": "GO:0097552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097552", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "R-loop processing", "id": "GO:0062176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062176", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" }, { "name": "maintenance of DNA trinucleotide repeats", "id": "GO:0035753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035753", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33301-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Ser349", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27017623", "url": "https://glygen.org/publication/PubMed/27017623" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Thr401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Ser405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "437", "end_pos": "437", "site_lbl": "Ser437", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "444", "end_pos": "444", "site_lbl": "Ser444", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "445", "end_pos": "445", "site_lbl": "Ser445", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Thr450", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "453", "end_pos": "453", "site_lbl": "Thr453", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "497", "end_pos": "497", "site_lbl": "Ser497", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Ser526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Ser529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "533", "end_pos": "533", "site_lbl": "Ser533", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "534", "end_pos": "534", "site_lbl": "Ser534", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Ser542", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Ser553", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "555", "end_pos": "555", "site_lbl": "Thr555", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33301", "url": "https://www.uniprot.org/uniprotkb/P33301" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Ser610", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "675", "end_pos": "675", "site_lbl": "Thr675", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "27017623", "url": "https://glygen.org/publication/PubMed/27017623" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "712", "end_pos": "712", "site_lbl": "Ser712", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "740", "end_pos": "740", "site_lbl": "Ser740", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "825", "end_pos": "825", "site_lbl": "Ser825", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P33301-1", "start_pos": "828", "end_pos": "828", "site_lbl": "Ser828", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002777", "url": "https://www.yeastgenome.org/locus/S000002777" }, { "database": "iPTMnet", "id": "P33301", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33301-1" }, { "uniprot_canonical_ac": "P33302-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1511, "chemical_mass": 170438.0, "gene_names": "PDR5;LEM1;PDR5;STS1;YDR1", "protein_name": "Pleiotropic ABC efflux transporter of multiple drugs", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" } ], "biological_process": [ { "name": "response to antibiotic", "id": "GO:0046677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046677", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" }, { "name": "intracellular monoatomic cation homeostasis", "id": "GO:0030003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030003", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" }, { "name": "response to cycloheximide", "id": "GO:0046898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046898", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" }, { "name": "xenobiotic detoxification by transmembrane export across the plasma membrane", "id": "GO:1990961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990961", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33302-1", "start_pos": "1447", "end_pos": "1447", "site_lbl": "Asn1447", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1447, "start_aa": "Asn", "end_pos": 1447, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1447", "evidence": [ { "id": "P33302", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P33302#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "734", "end_pos": "734", "site_lbl": "Asn734", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 734, "start_aa": "Asn", "end_pos": 734, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn734", "evidence": [ { "id": "P33302", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P33302#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Ser103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "1170", "end_pos": "1170", "site_lbl": "Ser1170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Ser318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "423", "end_pos": "423", "site_lbl": "Ser423", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "443", "end_pos": "443", "site_lbl": "Thr443", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Ser475", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Thr49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Thr51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Ser54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Thr59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "837", "end_pos": "837", "site_lbl": "Ser837", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "840", "end_pos": "840", "site_lbl": "Ser840", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "841", "end_pos": "841", "site_lbl": "Ser841", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "849", "end_pos": "849", "site_lbl": "Ser849", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "850", "end_pos": "850", "site_lbl": "Ser850", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "854", "end_pos": "854", "site_lbl": "Ser854", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "31757931", "url": "https://glygen.org/publication/PubMed/31757931" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "856", "end_pos": "856", "site_lbl": "Thr856", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "857", "end_pos": "857", "site_lbl": "Tyr857", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005679", "url": "https://www.yeastgenome.org/locus/S000005679" }, { "database": "iPTMnet", "id": "P33302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33302" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "1009", "end_pos": "1009", "site_lbl": "Gly1009", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "C", "comment": "Confers generalized drug resistance.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "1040", "end_pos": "1040", "site_lbl": "Gly1040", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Alters drug specificity.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "1048", "end_pos": "1048", "site_lbl": "Ser1048", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "V", "comment": "Alters drug specificity.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "1289", "end_pos": "1289", "site_lbl": "Glu1289", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Alters drug specificity.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "1311", "end_pos": "1311", "site_lbl": "Tyr1311", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "S", "comment": "Alters drug specificity.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "1360", "end_pos": "1360", "site_lbl": "Ser1360", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "F", "comment": "Alters drug specificity.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "1393", "end_pos": "1393", "site_lbl": "Thr1393", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "I", "comment": "Alters drug specificity.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "1427", "end_pos": "1427", "site_lbl": "Cys1427", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "Y", "comment": "Activates ER-associated degradation.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Leu183", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "Activates ER-associated degradation.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Thr257", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "I", "comment": "Alters drug specificity.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Gly302", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Confers generalized drug resistance.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "648", "end_pos": "648", "site_lbl": "Ser648", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "F", "comment": "Alters drug specificity.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "905", "end_pos": "905", "site_lbl": "Gly905", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "Inactivates drug transport.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] }, { "uniprot_canonical_ac": "P33302-1", "start_pos": "908", "end_pos": "908", "site_lbl": "Gly908", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "Inactivates drug transport.", "evidence": [ { "database": "UniProtKB", "id": "P33302", "url": "https://www.uniprot.org/uniprotkb/P33302" } ] } ] } ], "record_id": "P33302-1" }, { "uniprot_canonical_ac": "P33307-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33307", "url": "https://www.uniprot.org/uniprotkb/P33307" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 960, "chemical_mass": 109356.0, "gene_names": "CSE1;CSE1;HRC135;KAP109", "protein_name": "Importin alpha re-exporter", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "biological_process": [ { "name": "snRNA import into nucleus", "id": "GO:0061015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061015", "evidence": [ { "database": "UniProtKB", "id": "P33307", "url": "https://www.uniprot.org/uniprotkb/P33307" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P33307", "url": "https://www.uniprot.org/uniprotkb/P33307" } ], "pmid": "" }, { "name": "positive regulation of protein export from nucleus", "id": "GO:0046827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046827", "evidence": [ { "database": "UniProtKB", "id": "P33307", "url": "https://www.uniprot.org/uniprotkb/P33307" } ], "pmid": "" }, { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "P33307", "url": "https://www.uniprot.org/uniprotkb/P33307" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P33307", "url": "https://www.uniprot.org/uniprotkb/P33307" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P33307", "url": "https://www.uniprot.org/uniprotkb/P33307" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "P33307", "url": "https://www.uniprot.org/uniprotkb/P33307" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "P33307", "url": "https://www.uniprot.org/uniprotkb/P33307" } ], "pmid": "" }, { "name": "nuclear export signal receptor activity", "id": "GO:0005049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005049", "evidence": [ { "database": "UniProtKB", "id": "P33307", "url": "https://www.uniprot.org/uniprotkb/P33307" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33307-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Thr184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003207", "url": "https://www.yeastgenome.org/locus/S000003207" }, { "database": "iPTMnet", "id": "P33307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33307" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33307-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33307" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003207", "url": "https://www.yeastgenome.org/locus/S000003207" } ] } ] }, { "uniprot_canonical_ac": "P33307-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33307" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P33307-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003207", "url": "https://www.yeastgenome.org/locus/S000003207" }, { "database": "iPTMnet", "id": "P33307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33307" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33307-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Thr397", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003207", "url": "https://www.yeastgenome.org/locus/S000003207" }, { "database": "iPTMnet", "id": "P33307", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33307" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] } ], "record_id": "P33307-1" }, { "uniprot_canonical_ac": "P33308-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 149, "chemical_mass": 17376.0, "gene_names": "CSE2;CSE2;MED9;N2046", "protein_name": "Mediator of RNA polymerase II transcription subunit 9", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "P33308", "url": "https://www.uniprot.org/uniprotkb/P33308" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33308-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33308", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33308" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005293", "url": "https://www.yeastgenome.org/locus/S000005293" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33308-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005293", "url": "https://www.yeastgenome.org/locus/S000005293" }, { "database": "iPTMnet", "id": "P33308", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33308" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33308-1" }, { "uniprot_canonical_ac": "P33310-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33310", "url": "https://www.uniprot.org/uniprotkb/P33310" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 695, "chemical_mass": 75950.0, "gene_names": "MDL1;L9470.3;MDL1", "protein_name": "ATP-dependent permease MDL1, mitochondrial", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P33310", "url": "https://www.uniprot.org/uniprotkb/P33310" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P33310", "url": "https://www.uniprot.org/uniprotkb/P33310" } ], "pmid": "" }, { "name": "ABC-type oligopeptide transporter activity", "id": "GO:0015421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015421", "evidence": [ { "database": "UniProtKB", "id": "P33310", "url": "https://www.uniprot.org/uniprotkb/P33310" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P33310", "url": "https://www.uniprot.org/uniprotkb/P33310" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P33310", "url": "https://www.uniprot.org/uniprotkb/P33310" } ], "pmid": "" } ], "biological_process": [ { "name": "oligopeptide export from mitochondrion", "id": "GO:0090374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090374", "evidence": [ { "database": "UniProtKB", "id": "P33310", "url": "https://www.uniprot.org/uniprotkb/P33310" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33310-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004178", "url": "https://www.yeastgenome.org/locus/S000004178" }, { "database": "iPTMnet", "id": "P33310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33310" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33310-1", "start_pos": "467", "end_pos": "467", "site_lbl": "Gly467", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "V", "comment": "Decreased release of long peptides from mitochondria.", "evidence": [ { "database": "UniProtKB", "id": "P33310", "url": "https://www.uniprot.org/uniprotkb/P33310" }, { "database": "PubMed", "id": "11251115", "url": "https://glygen.org/publication/PubMed/11251115" } ] } ] }, { "uniprot_canonical_ac": "P33310-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Ser575", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "N", "comment": "Decreased release of long peptides from mitochondria.", "evidence": [ { "database": "UniProtKB", "id": "P33310", "url": "https://www.uniprot.org/uniprotkb/P33310" }, { "database": "PubMed", "id": "11251115", "url": "https://glygen.org/publication/PubMed/11251115" } ] } ] }, { "uniprot_canonical_ac": "P33310-1", "start_pos": "598", "end_pos": "598", "site_lbl": "Asp598", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Decreased release of long peptides from mitochondria.", "evidence": [ { "database": "UniProtKB", "id": "P33310", "url": "https://www.uniprot.org/uniprotkb/P33310" }, { "database": "PubMed", "id": "11251115", "url": "https://glygen.org/publication/PubMed/11251115" } ] } ] } ], "record_id": "P33310-1" }, { "uniprot_canonical_ac": "P33314-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1104, "chemical_mass": 126663.0, "gene_names": "BUD2;BUD2;CLA2;ERC25;YKL424", "protein_name": "Inhibitory regulator protein BUD2/CLA2", "disease": [ { "disease_id": "DOID:0050830", "name": "peripheral artery disease", "description": "An artery disease that is characterized by build up of plaque in the arteries that carry blood to your head, organs, and limbs.", "url": "https://disease-ontology.org/term/DOID:0050830", "evidence": [ { "id": "0050830", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050830" } ], "weight": 0.0 }, { "disease_id": "DOID:0070035", "name": "autosomal dominant intellectual developmental disorder 5", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the SYNGAP1 gene on chromosome 6p21.32.", "url": "https://disease-ontology.org/term/DOID:0070035", "evidence": [ { "id": "0070035", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070035" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries.", "url": "https://disease-ontology.org/term/DOID:1936", "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta.", "url": "https://disease-ontology.org/term/DOID:7693", "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 }, { "disease_id": "DOID:9477", "name": "pulmonary embolism", "description": "An artery disease characterized by a blockage of the main artery of the lung or one of its branches by a substance that has travelled from elsewhere in the body, e.g. a blood clot.", "url": "https://disease-ontology.org/term/DOID:9477", "evidence": [ { "id": "9477", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9477" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" }, { "name": "invasive growth in response to glucose limitation", "id": "GO:0001403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001403", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" }, { "name": "axial cellular bud site selection", "id": "GO:0007120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007120", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" }, { "name": "bipolar cellular bud site selection", "id": "GO:0007121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007121", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" }, { "name": "filamentous growth", "id": "GO:0030447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030447", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" }, { "name": "mitotic spindle orientation checkpoint signaling", "id": "GO:0031578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031578", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" }, { "name": "invasive filamentous growth", "id": "GO:0036267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036267", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33314-1", "start_pos": "987", "end_pos": "987", "site_lbl": "Thr987", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 987, "start_aa": "Thr", "end_pos": 987, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr987", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P33314", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P33314" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "991", "end_pos": "991", "site_lbl": "Ser991", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 991, "start_aa": "Ser", "end_pos": 991, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser991", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P33314", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P33314" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "992", "end_pos": "992", "site_lbl": "Ser992", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 992, "start_aa": "Ser", "end_pos": 992, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser992", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P33314", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P33314" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "1000", "end_pos": "1000", "site_lbl": "Thr1000", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "1066", "end_pos": "1066", "site_lbl": "Ser1066", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "1071", "end_pos": "1071", "site_lbl": "Ser1071", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "1092", "end_pos": "1092", "site_lbl": "Thr1092", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "34502421", "url": "https://glygen.org/publication/PubMed/34502421" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "1101", "end_pos": "1101", "site_lbl": "Thr1101", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "34502421", "url": "https://glygen.org/publication/PubMed/34502421" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "558", "end_pos": "558", "site_lbl": "Ser558", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Ser569", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "772", "end_pos": "772", "site_lbl": "Ser772", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "846", "end_pos": "846", "site_lbl": "Ser846", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "854", "end_pos": "854", "site_lbl": "Ser854", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33314", "url": "https://www.uniprot.org/uniprotkb/P33314" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "893", "end_pos": "893", "site_lbl": "Ser893", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "895", "end_pos": "895", "site_lbl": "Ser895", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "904", "end_pos": "904", "site_lbl": "Ser904", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33314-1", "start_pos": "944", "end_pos": "944", "site_lbl": "Ser944", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001575", "url": "https://www.yeastgenome.org/locus/S000001575" }, { "database": "iPTMnet", "id": "P33314", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33314" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33314-1" }, { "uniprot_canonical_ac": "P33317-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 147, "chemical_mass": 15307.0, "gene_names": "DUT1;DUT1;YBR1705", "protein_name": "Deoxyuridine 5'-triphosphate nucleotidohydrolase", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "biological_process": [ { "name": "dUMP biosynthetic process", "id": "GO:0006226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006226", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" } ], "pmid": "" }, { "name": "dUTP catabolic process", "id": "GO:0046081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046081", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" } ], "pmid": "" }, { "name": "dITP catabolic process", "id": "GO:0035863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035863", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" } ], "pmid": "" }, { "name": "pyrimidine deoxyribonucleoside triphosphate catabolic process", "id": "GO:0009213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009213", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" } ], "pmid": "" }, { "name": "dUTP diphosphatase activity", "id": "GO:0004170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004170", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" } ], "pmid": "" }, { "name": "dITP diphosphatase activity", "id": "GO:0035870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035870", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33317-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000456", "url": "https://www.yeastgenome.org/locus/S000000456" }, { "database": "iPTMnet", "id": "P33317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33317" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000456", "url": "https://www.yeastgenome.org/locus/S000000456" }, { "database": "iPTMnet", "id": "P33317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33317" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000456", "url": "https://www.yeastgenome.org/locus/S000000456" }, { "database": "iPTMnet", "id": "P33317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33317" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Tyr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33317" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ], "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Exhibits reduced activity and lower substrate affinity.", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" }, { "database": "PubMed", "id": "21548881", "url": "https://glygen.org/publication/PubMed/21548881" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33317", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33317" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000456", "url": "https://www.yeastgenome.org/locus/S000000456" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Arg111", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Exhibits reduced activity and lower substrate affinity.", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" }, { "database": "PubMed", "id": "21548881", "url": "https://glygen.org/publication/PubMed/21548881" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Gln114", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Does not affect the affinity for dUTP but greatly reduces activity.", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" }, { "database": "PubMed", "id": "21548881", "url": "https://glygen.org/publication/PubMed/21548881" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Arg137", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Exhibits negligible activity.", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" }, { "database": "PubMed", "id": "21548881", "url": "https://glygen.org/publication/PubMed/21548881" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Phe142", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Exhibits very low activity.", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" }, { "database": "PubMed", "id": "21548881", "url": "https://glygen.org/publication/PubMed/21548881" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Asp32", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Exhibits negligible activity.", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" }, { "database": "PubMed", "id": "21548881", "url": "https://glygen.org/publication/PubMed/21548881" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Arg68", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Exhibits very low activity.", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" }, { "database": "PubMed", "id": "21548881", "url": "https://glygen.org/publication/PubMed/21548881" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Exhibits negligible activity.", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" }, { "database": "PubMed", "id": "21548881", "url": "https://glygen.org/publication/PubMed/21548881" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Asp85", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Exhibits negligible activity.", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" }, { "database": "PubMed", "id": "21548881", "url": "https://glygen.org/publication/PubMed/21548881" } ] } ] }, { "uniprot_canonical_ac": "P33317-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Asp87", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Exhibits negligible activity.", "evidence": [ { "database": "UniProtKB", "id": "P33317", "url": "https://www.uniprot.org/uniprotkb/P33317" }, { "database": "PubMed", "id": "21548881", "url": "https://glygen.org/publication/PubMed/21548881" } ] } ] } ], "record_id": "P33317-1" }, { "uniprot_canonical_ac": "P33322-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 483, "chemical_mass": 54705.0, "gene_names": "CBF5;CBF5;L9470.11", "protein_name": "H/ACA ribonucleoprotein complex subunit CBF5", "disease": [ { "disease_id": "DOID:0070025", "name": "X-linked dyskeratosis congenita", "description": "A dyskeratosis congenita that has_material_basis_in an X-linked recessive mutation of the DKC1 gene on chromosome Xq28.", "url": "https://disease-ontology.org/term/DOID:0070025", "evidence": [ { "id": "0070025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070025" } ], "weight": 0.0 }, { "disease_id": "DOID:12449", "name": "aplastic anemia", "description": "A normocytic anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow.", "url": "https://disease-ontology.org/term/DOID:12449", "evidence": [ { "id": "12449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12449" } ], "weight": 0.0 }, { "disease_id": "DOID:2729", "name": "dyskeratosis congenita", "description": "A skin disease characterized by cutaneous pigmentation, premature graying, dystrophy of the nails, leukoplakia of the oral mucosa, continuous lacrimation due to atresia of the lacrimal ducts, often thrombocytopenia, anemia, testicular atrophy in the male carriers and predisposition to cancer.", "url": "https://disease-ontology.org/term/DOID:2729", "evidence": [ { "id": "2729", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2729" } ], "weight": 0.0 } ], "biological_process": [ { "name": "rRNA modification", "id": "GO:0000154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000154", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "box H/ACA sno(s)RNA 3'-end processing", "id": "GO:0000495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000495", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "rRNA pseudouridine synthesis", "id": "GO:0031118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031118", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "snRNA pseudouridine synthesis", "id": "GO:0031120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031120", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "mRNA pseudouridine synthesis", "id": "GO:1990481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990481", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "snoRNA guided rRNA pseudouridine synthesis", "id": "GO:0000454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000454", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "snRNA pseudouridine synthase activity", "id": "GO:0106032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106032", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "box H/ACA snoRNP complex", "id": "GO:0031429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031429", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33322-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Ser254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "378", "end_pos": "378", "site_lbl": "Thr378", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Ser395", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Thr396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Ser397", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Ser398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Thr402", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Thr405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Thr40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Ser416", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "423", "end_pos": "423", "site_lbl": "Thr423", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Ser468", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Ser473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004165", "url": "https://www.yeastgenome.org/locus/S000004165" }, { "database": "iPTMnet", "id": "P33322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33322" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Asp65", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduced pseudouridylation of rRNA and reduced snoRNA levels.", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" }, { "database": "PubMed", "id": "10523634", "url": "https://glygen.org/publication/PubMed/10523634" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Leu94", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Reduced pseudouridylation of rRNA.", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" }, { "database": "PubMed", "id": "10523634", "url": "https://glygen.org/publication/PubMed/10523634" } ] } ] }, { "uniprot_canonical_ac": "P33322-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Asp95", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolished pseudouridylation of rRNA. Abolishes pseudouridylation at position 93 in U2 snRNA.", "evidence": [ { "database": "UniProtKB", "id": "P33322", "url": "https://www.uniprot.org/uniprotkb/P33322" }, { "database": "PubMed", "id": "21131909", "url": "https://glygen.org/publication/PubMed/21131909" }, { "database": "PubMed", "id": "10523634", "url": "https://glygen.org/publication/PubMed/10523634" } ] } ] } ], "record_id": "P33322-1" }, { "uniprot_canonical_ac": "P33327-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33327", "url": "https://www.uniprot.org/uniprotkb/P33327" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1092, "chemical_mass": 124332.0, "gene_names": "GDH2;D0892;GDH2", "protein_name": "NAD-specific glutamate dehydrogenase", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P33327", "url": "https://www.uniprot.org/uniprotkb/P33327" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P33327", "url": "https://www.uniprot.org/uniprotkb/P33327" } ], "pmid": "" } ], "biological_process": [ { "name": "alcohol metabolic process", "id": "GO:0006066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006066", "evidence": [ { "database": "UniProtKB", "id": "P33327", "url": "https://www.uniprot.org/uniprotkb/P33327" } ], "pmid": "" }, { "name": "L-glutamate catabolic process", "id": "GO:0006538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006538", "evidence": [ { "database": "UniProtKB", "id": "P33327", "url": "https://www.uniprot.org/uniprotkb/P33327" } ], "pmid": "" } ], "molecular_function": [ { "name": "glutamate dehydrogenase (NAD+) activity", "id": "GO:0004352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004352", "evidence": [ { "database": "UniProtKB", "id": "P33327", "url": "https://www.uniprot.org/uniprotkb/P33327" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33327-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Ser150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002374", "url": "https://www.yeastgenome.org/locus/S000002374" }, { "database": "iPTMnet", "id": "P33327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33327-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Thr157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002374", "url": "https://www.yeastgenome.org/locus/S000002374" }, { "database": "iPTMnet", "id": "P33327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33327-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002374", "url": "https://www.yeastgenome.org/locus/S000002374" }, { "database": "iPTMnet", "id": "P33327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33327-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002374", "url": "https://www.yeastgenome.org/locus/S000002374" }, { "database": "iPTMnet", "id": "P33327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P33327-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002374", "url": "https://www.yeastgenome.org/locus/S000002374" }, { "database": "iPTMnet", "id": "P33327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33327" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33327-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33327" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002374", "url": "https://www.yeastgenome.org/locus/S000002374" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33327-1", "start_pos": "480", "end_pos": "480", "site_lbl": "Thr480", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33327" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P33327-1", "start_pos": "482", "end_pos": "482", "site_lbl": "Ser482", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33327" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002374", "url": "https://www.yeastgenome.org/locus/S000002374" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33327-1", "start_pos": "510", "end_pos": "510", "site_lbl": "Ser510", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002374", "url": "https://www.yeastgenome.org/locus/S000002374" }, { "database": "iPTMnet", "id": "P33327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33327" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P33327-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Thr518", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002374", "url": "https://www.yeastgenome.org/locus/S000002374" }, { "database": "iPTMnet", "id": "P33327", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33327" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] } ], "record_id": "P33327-1" }, { "uniprot_canonical_ac": "P33328-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 115, "chemical_mass": 12957.0, "gene_names": "SNC2;SNC2", "protein_name": "Synaptobrevin homolog 2", "disease": [], "biological_process": [ { "name": "Golgi vesicle fusion to target membrane", "id": "GO:0048210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048210", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "vesicle fusion with Golgi apparatus", "id": "GO:0048280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048280", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "vesicle fusion to plasma membrane", "id": "GO:0099500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099500", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "ascospore-type prospore assembly", "id": "GO:0031321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031321", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "sporulation", "id": "GO:0043934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043934", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33328-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005854", "url": "https://www.yeastgenome.org/locus/S000005854" }, { "database": "iPTMnet", "id": "P33328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33328" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33328-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33328", "url": "https://www.uniprot.org/uniprotkb/P33328" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33328" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000005854", "url": "https://www.yeastgenome.org/locus/S000005854" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33328-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33328" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005854", "url": "https://www.yeastgenome.org/locus/S000005854" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33328-1" }, { "uniprot_canonical_ac": "P33333-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33333", "url": "https://www.uniprot.org/uniprotkb/P33333" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 303, "chemical_mass": 33887.0, "gene_names": "SLC1;SLC1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "disease": [ { "disease_id": "DOID:0111135", "name": "congenital generalized lipodystrophy type 1", "description": "A congenital generalized lipodystrophy that has_material_basis_in an autosomal recessive mutation of AGPAT2 on chromosome 9q34.3.", "url": "https://disease-ontology.org/term/DOID:0111135", "evidence": [ { "id": "0111135", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111135" } ], "weight": 0.0 }, { "disease_id": "DOID:811", "name": "lipodystrophy", "description": "A connective tissue disease that is characterized by marked reduction, absence, and/or the redistribution of adipose tissue.", "url": "https://disease-ontology.org/term/DOID:811", "evidence": [ { "id": "811", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:811" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "1-acylglycerol-3-phosphate O-acyltransferase activity", "id": "GO:0003841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003841", "evidence": [ { "database": "UniProtKB", "id": "P33333", "url": "https://www.uniprot.org/uniprotkb/P33333" } ], "pmid": "" }, { "name": "1-acylglycerophosphocholine O-acyltransferase activity", "id": "GO:0047184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047184", "evidence": [ { "database": "UniProtKB", "id": "P33333", "url": "https://www.uniprot.org/uniprotkb/P33333" } ], "pmid": "" }, { "name": "1-acylglycerophosphoethanolamine O-acyltransferase activity", "id": "GO:0106262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106262", "evidence": [ { "database": "UniProtKB", "id": "P33333", "url": "https://www.uniprot.org/uniprotkb/P33333" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P33333", "url": "https://www.uniprot.org/uniprotkb/P33333" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P33333", "url": "https://www.uniprot.org/uniprotkb/P33333" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P33333", "url": "https://www.uniprot.org/uniprotkb/P33333" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidic acid biosynthetic process", "id": "GO:0006654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006654", "evidence": [ { "database": "UniProtKB", "id": "P33333", "url": "https://www.uniprot.org/uniprotkb/P33333" } ], "pmid": "" }, { "name": "glycerophospholipid biosynthetic process", "id": "GO:0046474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046474", "evidence": [ { "database": "UniProtKB", "id": "P33333", "url": "https://www.uniprot.org/uniprotkb/P33333" } ], "pmid": "" }, { "name": "CDP-diacylglycerol biosynthetic process", "id": "GO:0016024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016024", "evidence": [ { "database": "UniProtKB", "id": "P33333", "url": "https://www.uniprot.org/uniprotkb/P33333" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33333-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Thr162", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002210", "url": "https://www.yeastgenome.org/locus/S000002210" }, { "database": "iPTMnet", "id": "P33333", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33333" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33333-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002210", "url": "https://www.yeastgenome.org/locus/S000002210" }, { "database": "iPTMnet", "id": "P33333", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33333" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33333-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002210", "url": "https://www.yeastgenome.org/locus/S000002210" }, { "database": "iPTMnet", "id": "P33333", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33333" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33333-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Thr292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002210", "url": "https://www.yeastgenome.org/locus/S000002210" }, { "database": "iPTMnet", "id": "P33333", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33333" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33333-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002210", "url": "https://www.yeastgenome.org/locus/S000002210" }, { "database": "iPTMnet", "id": "P33333", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33333" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33333-1" }, { "uniprot_canonical_ac": "P33334-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 2413, "chemical_mass": 279504.0, "gene_names": "PRP8;DBF3;DNA39;PRP8;RNA8;SLT21;USA2", "protein_name": "Pre-mRNA-splicing factor 8", "disease": [ { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0110403", "name": "retinitis pigmentosa 13", "description": "A retinitis pigmentosa that has_material_basis_in mutations in the PRPF8 gene on chromosome 17p13.3.", "url": "https://disease-ontology.org/term/DOID:0110403", "evidence": [ { "id": "0110403", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110403" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "pre-mRNA intronic binding", "id": "GO:0097157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097157", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "U2 snRNA binding", "id": "GO:0030620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030620", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "U6 snRNA binding", "id": "GO:0017070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017070", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "U5 snRNA binding", "id": "GO:0030623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030623", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "Prp19 complex", "id": "GO:0000974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000974", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" } ], "biological_process": [ { "name": "spliceosomal tri-snRNP complex assembly", "id": "GO:0000244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000244", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "generation of catalytic spliceosome for second transesterification step", "id": "GO:0000350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000350", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" }, { "name": "mRNA 3'-splice site recognition", "id": "GO:0000389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000389", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33334-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Thr145", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 145, "start_aa": "Thr", "end_pos": 145, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr145", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P33334", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P33334" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 147, "start_aa": "Ser", "end_pos": 147, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser147", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P33334", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P33334" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 151, "start_aa": "Ser", "end_pos": 151, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser151", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P33334", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P33334" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Thr156", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 156, "start_aa": "Thr", "end_pos": 156, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr156", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P33334", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P33334" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1584", "end_pos": "1584", "site_lbl": "Ser1584", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001208", "url": "https://www.yeastgenome.org/locus/S000001208" }, { "database": "iPTMnet", "id": "P33334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33334" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1906", "end_pos": "1906", "site_lbl": "Ser1906", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001208", "url": "https://www.yeastgenome.org/locus/S000001208" }, { "database": "iPTMnet", "id": "P33334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33334" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "2143", "end_pos": "2143", "site_lbl": "Ser2143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001208", "url": "https://www.yeastgenome.org/locus/S000001208" }, { "database": "iPTMnet", "id": "P33334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33334" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Tyr364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33334" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001208", "url": "https://www.yeastgenome.org/locus/S000001208" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "896", "end_pos": "896", "site_lbl": "Ser896", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001208", "url": "https://www.yeastgenome.org/locus/S000001208" }, { "database": "iPTMnet", "id": "P33334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33334" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1658", "end_pos": "1658", "site_lbl": "His1658", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "S", "comment": "No effect on viability.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "23354046", "url": "https://glygen.org/publication/PubMed/23354046" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1684", "end_pos": "1684", "site_lbl": "Glu1684", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "No effect on viability.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "23354046", "url": "https://glygen.org/publication/PubMed/23354046" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1687", "end_pos": "1687", "site_lbl": "His1687", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "S", "comment": "No effect on viability.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "23354046", "url": "https://glygen.org/publication/PubMed/23354046" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1700", "end_pos": "1700", "site_lbl": "Asp1700", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "No effect on viability.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "23354046", "url": "https://glygen.org/publication/PubMed/23354046" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1735", "end_pos": "1735", "site_lbl": "Asp1735", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "No effect on viability.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "23354046", "url": "https://glygen.org/publication/PubMed/23354046" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1853", "end_pos": "1853", "site_lbl": "Asp1853", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Alters protein folding. Severely impaired growth. Strongly reduced growth at 35 degrees Celsius; when associated with A-1854.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "18836455", "url": "https://glygen.org/publication/PubMed/18836455" }, { "database": "PubMed", "id": "18779563", "url": "https://glygen.org/publication/PubMed/18779563" }, { "database": "PubMed", "id": "18843295", "url": "https://glygen.org/publication/PubMed/18843295" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Reduced growth at 30 degrees Celsius. Strongly reduced growth at 16 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "18836455", "url": "https://glygen.org/publication/PubMed/18836455" }, { "database": "PubMed", "id": "18779563", "url": "https://glygen.org/publication/PubMed/18779563" }, { "database": "PubMed", "id": "18843295", "url": "https://glygen.org/publication/PubMed/18843295" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1854", "end_pos": "1854", "site_lbl": "Asp1854", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduced growth at 30 degrees Celsius. Strongly reduced growth at 16 degrees Celsius. Strongly reduced growth at 35 degrees Celsius; when associated with A-1853.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "18836455", "url": "https://glygen.org/publication/PubMed/18836455" }, { "database": "PubMed", "id": "18843295", "url": "https://glygen.org/publication/PubMed/18843295" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Reduced growth at 30 degrees Celsius. Strongly reduced growth at 16 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "18836455", "url": "https://glygen.org/publication/PubMed/18836455" }, { "database": "PubMed", "id": "18843295", "url": "https://glygen.org/publication/PubMed/18843295" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1855", "end_pos": "1855", "site_lbl": "Thr1855", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Reduced growth at 30 degrees Celsius. Strongly reduced growth at 16 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "18843295", "url": "https://glygen.org/publication/PubMed/18843295" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1936", "end_pos": "1936", "site_lbl": "Thr1936", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Reduced growth at 30 degrees Celsius. Strongly reduced growth at 16 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "18843295", "url": "https://glygen.org/publication/PubMed/18843295" } ] } ] }, { "uniprot_canonical_ac": "P33334-1", "start_pos": "1937", "end_pos": "1937", "site_lbl": "Arg1937", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "K", "comment": "Severely impaired growth. Reduced growth at 30 degrees Celsius. Strongly reduced growth at 16 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P33334", "url": "https://www.uniprot.org/uniprotkb/P33334" }, { "database": "PubMed", "id": "18843295", "url": "https://glygen.org/publication/PubMed/18843295" } ] } ] } ], "record_id": "P33334-1" }, { "uniprot_canonical_ac": "P33338-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 968, "chemical_mass": 108911.0, "gene_names": "SLA2;END4;MOP2;N1102;SLA2;UFG1", "protein_name": "Protein SLA2", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "clathrin coat assembly", "id": "GO:0048268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048268", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "negative regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034316", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "actin cortical patch assembly", "id": "GO:0000147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000147", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3,4-bisphosphate binding", "id": "GO:0043325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043325", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" }, { "name": "clathrin light chain binding", "id": "GO:0032051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032051", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33338-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Thr298", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 298, "start_aa": "Thr", "end_pos": 298, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr298", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ser273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Thr286", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Thr290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Thr294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Thr296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Ser308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "480", "end_pos": "480", "site_lbl": "Ser480", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "547", "end_pos": "547", "site_lbl": "Ser547", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "555", "end_pos": "555", "site_lbl": "Ser555", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33338", "url": "https://www.uniprot.org/uniprotkb/P33338" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "559", "end_pos": "559", "site_lbl": "Thr559", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Thr564", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "566", "end_pos": "566", "site_lbl": "Thr566", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "726", "end_pos": "726", "site_lbl": "Ser726", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "737", "end_pos": "737", "site_lbl": "Ser737", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "740", "end_pos": "740", "site_lbl": "Ser740", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "948", "end_pos": "948", "site_lbl": "Ser948", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33338-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Ser97", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005187", "url": "https://www.yeastgenome.org/locus/S000005187" }, { "database": "iPTMnet", "id": "P33338", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33338" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33338-1" }, { "uniprot_canonical_ac": "P33339-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1025, "chemical_mass": 120229.0, "gene_names": "TFC4;PCF1;TFC4", "protein_name": "Transcription factor tau 131 kDa subunit", "disease": [], "cellular_component": [ { "name": "transcription factor TFIIIC complex", "id": "GO:0000127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000127", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" } ], "pmid": "" } ], "biological_process": [ { "name": "5S class rRNA transcription by RNA polymerase III", "id": "GO:0042791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042791", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" } ], "pmid": "" }, { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33339-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003279", "url": "https://www.yeastgenome.org/locus/S000003279" }, { "database": "iPTMnet", "id": "P33339", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33339" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33339", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33339" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003279", "url": "https://www.yeastgenome.org/locus/S000003279" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "311", "end_pos": "311", "site_lbl": "Ser311", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33339", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33339" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003279", "url": "https://www.yeastgenome.org/locus/S000003279" }, { "database": "iPTMnet", "id": "P33339", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33339" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Thr395", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003279", "url": "https://www.yeastgenome.org/locus/S000003279" }, { "database": "iPTMnet", "id": "P33339", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33339" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "587", "end_pos": "587", "site_lbl": "Ser587", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003279", "url": "https://www.yeastgenome.org/locus/S000003279" }, { "database": "iPTMnet", "id": "P33339", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33339" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "609", "end_pos": "609", "site_lbl": "Thr609", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003279", "url": "https://www.yeastgenome.org/locus/S000003279" }, { "database": "iPTMnet", "id": "P33339", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33339" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003279", "url": "https://www.yeastgenome.org/locus/S000003279" }, { "database": "iPTMnet", "id": "P33339", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33339" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003279", "url": "https://www.yeastgenome.org/locus/S000003279" }, { "database": "iPTMnet", "id": "P33339", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33339" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003279", "url": "https://www.yeastgenome.org/locus/S000003279" }, { "database": "iPTMnet", "id": "P33339", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33339" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Glu148", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "In PCF1-17; increases RNA polymerase III gene transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "9372943", "url": "https://glygen.org/publication/PubMed/9372943" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Phe162", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "L", "comment": "In PCF1-12; increases RNA polymerase III gene transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "9372943", "url": "https://glygen.org/publication/PubMed/9372943" } ] }, { "sequence_org": "F", "sequence_mut": "S", "comment": "In PCF1-139; increases RNA polymerase III gene transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "9372943", "url": "https://glygen.org/publication/PubMed/9372943" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ala164", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "V", "comment": "In PCF1-19; increases RNA polymerase III gene transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "9372943", "url": "https://glygen.org/publication/PubMed/9372943" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Thr167", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "I", "comment": "In PCF1-2; increases RNA polymerase III gene transcription due to an increase in the recruitment of BRF1 to TFIIIC-DNA. No effect on affinity of TFIIIC for DNA.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "9372943", "url": "https://glygen.org/publication/PubMed/9372943" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Tyr172", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "C", "comment": "In PCF1-11; increases RNA polymerase III gene transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ala188", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "T", "comment": "In PCF1-23; increases RNA polymerase III gene transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "9372943", "url": "https://glygen.org/publication/PubMed/9372943" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "190", "end_pos": "190", "site_lbl": "His190", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "In PCF1-1; affects the rate of recruitment of TFIIIB to the template. Increases the amount of transcriptionally active TFIIIB. Increases RNA polymerase III gene transcription. Increases the binding affinity for BRF1, but does not affect the binding affinity for BDP1 in the TFIIIC-dependent assembly of TFIIIB. Overcomes autoinhibition of BRF1 binding.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "8264649", "url": "https://glygen.org/publication/PubMed/8264649" }, { "database": "PubMed", "id": "7488859", "url": "https://glygen.org/publication/PubMed/7488859" }, { "database": "PubMed", "id": "9372943", "url": "https://glygen.org/publication/PubMed/9372943" }, { "database": "PubMed", "id": "12167707", "url": "https://glygen.org/publication/PubMed/12167707" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Asn192", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "L", "comment": "In PCF1-138; increases RNA polymerase III gene transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "9372943", "url": "https://glygen.org/publication/PubMed/9372943" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Trp199", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "R", "comment": "In PCF1-15; increases RNA polymerase III gene transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "9372943", "url": "https://glygen.org/publication/PubMed/9372943" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Leu469", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "K", "comment": "RNA polymerase III defective. Defect in the recruitment of BRF1 into TFIIIB-TFIIIC-DNA complexes and diminished direct interaction between TFC4 and BRF1. Decreased binding affinity for BDP1 incorporation into TFIIIB-TFIIIC-DNA complexes and inhibited binary interaction between BDP1 and TFC4.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "12930823", "url": "https://glygen.org/publication/PubMed/12930823" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Glu472", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "RNA polymerase III defective.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "12930823", "url": "https://glygen.org/publication/PubMed/12930823" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Val504", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "K", "comment": "RNA polymerase III defective.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "12930823", "url": "https://glygen.org/publication/PubMed/12930823" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "541", "end_pos": "541", "site_lbl": "Ser541", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "I", "comment": "RNA polymerase III defective.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "12930823", "url": "https://glygen.org/publication/PubMed/12930823" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Leu542", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "G", "comment": "RNA polymerase III defective.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "12930823", "url": "https://glygen.org/publication/PubMed/12930823" } ] } ] }, { "uniprot_canonical_ac": "P33339-1", "start_pos": "728", "end_pos": "728", "site_lbl": "Arg728", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "In PCF1-8; increases RNA polymerase III transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "7488859", "url": "https://glygen.org/publication/PubMed/7488859" } ] }, { "sequence_org": "R", "sequence_mut": "G", "comment": "In PCF1-7; increases RNA polymerase III transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "7488859", "url": "https://glygen.org/publication/PubMed/7488859" } ] }, { "sequence_org": "R", "sequence_mut": "H", "comment": "In PCF1-4; increases RNA polymerase III transcription ninefold over wild-type. Increases the amount of transcriptionally active TFIIIB.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "7488859", "url": "https://glygen.org/publication/PubMed/7488859" } ] }, { "sequence_org": "R", "sequence_mut": "K", "comment": "In PCF1-3; increases RNA polymerase III transcription two- to threefold over wild-type. Increases the amount of transcriptionally active TFIIIB.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "7488859", "url": "https://glygen.org/publication/PubMed/7488859" } ] }, { "sequence_org": "R", "sequence_mut": "M", "comment": "In PCF1-5; increases RNA polymerase III transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "7488859", "url": "https://glygen.org/publication/PubMed/7488859" } ] }, { "sequence_org": "R", "sequence_mut": "V", "comment": "In PCF1-6; increases RNA polymerase III transcription.", "evidence": [ { "database": "UniProtKB", "id": "P33339", "url": "https://www.uniprot.org/uniprotkb/P33339" }, { "database": "PubMed", "id": "7488859", "url": "https://glygen.org/publication/PubMed/7488859" } ] } ] } ], "record_id": "P33339-1" }, { "uniprot_canonical_ac": "P33399-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 275, "chemical_mass": 32104.0, "gene_names": "LHP1;LAH1;LHP1;YLA1", "protein_name": "La protein homolog", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" } ], "pmid": "" }, { "name": "U6 snRNA binding", "id": "GO:0017070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017070", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33399-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "11720288", "url": "https://glygen.org/publication/PubMed/11720288" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Prevents phosphorylation; when associated with A-19 and A-235.", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" }, { "database": "PubMed", "id": "11720288", "url": "https://glygen.org/publication/PubMed/11720288" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "11720288", "url": "https://glygen.org/publication/PubMed/11720288" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Prevents phosphorylation; when associated with A-15 and A-235.", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" }, { "database": "PubMed", "id": "11720288", "url": "https://glygen.org/publication/PubMed/11720288" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" }, { "database": "PubMed", "id": "11720288", "url": "https://glygen.org/publication/PubMed/11720288" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Prevents phosphorylation; when associated with A-15 and A-19.", "evidence": [ { "database": "UniProtKB", "id": "P33399", "url": "https://www.uniprot.org/uniprotkb/P33399" }, { "database": "PubMed", "id": "11720288", "url": "https://glygen.org/publication/PubMed/11720288" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Ser263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Ser264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Thr26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33399-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002209", "url": "https://www.yeastgenome.org/locus/S000002209" }, { "database": "iPTMnet", "id": "P33399", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33399" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33399-1" }, { "uniprot_canonical_ac": "P33400-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 625, "chemical_mass": 68232.0, "gene_names": "RIM101;RIM101;RIM1", "protein_name": "pH-response transcription factor pacC/RIM101", "disease": [], "biological_process": [ { "name": "cellular response to anoxia", "id": "GO:0071454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071454", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "cellular response to alkaline pH", "id": "GO:0071469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071469", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "fungal-type cell wall biogenesis", "id": "GO:0009272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009272", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "positive regulation of division septum assembly", "id": "GO:0010973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010973", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "ascospore formation", "id": "GO:0030437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030437", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33400-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Thr109", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 109, "start_aa": "Thr", "end_pos": 109, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr109", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Ser42", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 42, "start_aa": "Ser", "end_pos": 42, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser42", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P33400", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P33400" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33400" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20382759", "url": "https://glygen.org/publication/PubMed/20382759" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001019", "url": "https://www.yeastgenome.org/locus/S000001019" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 46, "start_aa": "Ser", "end_pos": 46, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser46", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P33400", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P33400" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33400" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001019", "url": "https://www.yeastgenome.org/locus/S000001019" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33400" }, { "database": "PubMed", "id": "20382759", "url": "https://glygen.org/publication/PubMed/20382759" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33400" }, { "database": "PubMed", "id": "20382759", "url": "https://glygen.org/publication/PubMed/20382759" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001019", "url": "https://www.yeastgenome.org/locus/S000001019" }, { "database": "iPTMnet", "id": "P33400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33400" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Ser287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33400" }, { "database": "PubMed", "id": "20382759", "url": "https://glygen.org/publication/PubMed/20382759" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Ser304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33400" }, { "database": "PubMed", "id": "20382759", "url": "https://glygen.org/publication/PubMed/20382759" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Ser329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001019", "url": "https://www.yeastgenome.org/locus/S000001019" }, { "database": "iPTMnet", "id": "P33400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33400" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33400" }, { "database": "PubMed", "id": "20382759", "url": "https://glygen.org/publication/PubMed/20382759" }, { "database": "SGD", "id": "S000001019", "url": "https://www.yeastgenome.org/locus/S000001019" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Thr95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33400" }, { "database": "PubMed", "id": "20382759", "url": "https://glygen.org/publication/PubMed/20382759" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Cys153", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes transcriptional activation of target genes.", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" }, { "database": "PubMed", "id": "8367297", "url": "https://glygen.org/publication/PubMed/8367297" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Cys189", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes transcriptional activation of target genes.", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" }, { "database": "PubMed", "id": "8367297", "url": "https://glygen.org/publication/PubMed/8367297" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Cys217", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes transcriptional activation of target genes.", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" }, { "database": "PubMed", "id": "8367297", "url": "https://glygen.org/publication/PubMed/8367297" } ] } ] }, { "uniprot_canonical_ac": "P33400-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Ser255", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces transcriptional activation of target genes.", "evidence": [ { "database": "UniProtKB", "id": "P33400", "url": "https://www.uniprot.org/uniprotkb/P33400" }, { "database": "PubMed", "id": "8367297", "url": "https://glygen.org/publication/PubMed/8367297" } ] } ] } ], "record_id": "P33400-1" }, { "uniprot_canonical_ac": "P33401-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 570, "chemical_mass": 63112.0, "gene_names": "PGM1;PGM1", "protein_name": "Phosphoglucomutase 1", "disease": [ { "disease_id": "DOID:0080570", "name": "congenital disorder of glycosylation It", "description": "A congenital disorder of glycosylation I that is characterized by a wide range of clinical manifestations, most commonly presenting with bifid uvula with or without cleft palate at birth, associated with growth delay, hepatopathy with elevated aminotransferase serum levels, myopathy (including exercise-related fatigue, exercise intolerance, muscle weakness), intermittent hypoglycemia, and dilated cardiomyopathy and/or cardiac arrest, due to decreased phosphoglucomutase 1 enzyme activity and has_material_basis_in homozygous or compound heterozygous mutation in the PGM1 gene on chromosome 1p31.", "url": "https://disease-ontology.org/term/DOID:0080570", "evidence": [ { "id": "0080570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080570" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:3307", "name": "teratoma", "description": "A germ cell and embryonal cancer that is an encapsulated tumor with tissue or organ components resembling normal derivatives of all three germ layers.", "url": "https://disease-ontology.org/term/DOID:3307", "evidence": [ { "id": "3307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3307" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" }, { "name": "phosphoglucomutase activity", "id": "GO:0004614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004614", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" }, { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" }, { "name": "glycogen biosynthetic process", "id": "GO:0005978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005978", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" }, { "name": "glucose 1-phosphate metabolic process", "id": "GO:0019255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019255", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" }, { "name": "galactose catabolic process", "id": "GO:0019388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019388", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" }, { "name": "UDP-alpha-D-glucose metabolic process", "id": "GO:0006011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006011", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" }, { "name": "glucose 6-phosphate metabolic process", "id": "GO:0051156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051156", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" }, { "name": "trehalose biosynthetic process", "id": "GO:0005992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005992", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33401-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Thr105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001610", "url": "https://www.yeastgenome.org/locus/S000001610" }, { "database": "iPTMnet", "id": "P33401", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33401" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33401-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Tyr106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001610", "url": "https://www.yeastgenome.org/locus/S000001610" }, { "database": "iPTMnet", "id": "P33401", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33401" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33401-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Thr118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33401", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33401" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001610", "url": "https://www.yeastgenome.org/locus/S000001610" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33401-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33401", "url": "https://www.uniprot.org/uniprotkb/P33401" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P33401", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33401" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001610", "url": "https://www.yeastgenome.org/locus/S000001610" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33401-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Ser337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001610", "url": "https://www.yeastgenome.org/locus/S000001610" }, { "database": "iPTMnet", "id": "P33401", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33401" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33401-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Thr96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001610", "url": "https://www.yeastgenome.org/locus/S000001610" }, { "database": "iPTMnet", "id": "P33401", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33401" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33401-1" }, { "uniprot_canonical_ac": "P33413-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33413", "url": "https://www.uniprot.org/uniprotkb/P33413" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 735, "chemical_mass": 80617.0, "gene_names": "DUR3;DUR3", "protein_name": "Urea active transporter", "disease": [ { "disease_id": "DOID:0050328", "name": "congenital hypothyroidism", "description": "A hypothyroidism that is present at birth.", "url": "https://disease-ontology.org/term/DOID:0050328", "evidence": [ { "id": "0050328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050328" } ], "weight": 0.0 }, { "disease_id": "DOID:0112185", "name": "thyroid dyshormonogenesis 1", "description": "A familial thyroid dyshormonogenesis that has_material_basis_in homozygous or compound heterozygous mutation in SLC5A5 on chromosome 19p13.11.", "url": "https://disease-ontology.org/term/DOID:0112185", "evidence": [ { "id": "0112185", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112185" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P33413", "url": "https://www.uniprot.org/uniprotkb/P33413" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P33413", "url": "https://www.uniprot.org/uniprotkb/P33413" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P33413", "url": "https://www.uniprot.org/uniprotkb/P33413" } ], "pmid": "" } ], "biological_process": [ { "name": "urea transport", "id": "GO:0015840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015840", "evidence": [ { "database": "UniProtKB", "id": "P33413", "url": "https://www.uniprot.org/uniprotkb/P33413" } ], "pmid": "" }, { "name": "putrescine transport", "id": "GO:0015847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015847", "evidence": [ { "database": "UniProtKB", "id": "P33413", "url": "https://www.uniprot.org/uniprotkb/P33413" } ], "pmid": "" }, { "name": "spermidine transport", "id": "GO:0015848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015848", "evidence": [ { "database": "UniProtKB", "id": "P33413", "url": "https://www.uniprot.org/uniprotkb/P33413" } ], "pmid": "" } ], "molecular_function": [ { "name": "putrescine transmembrane transporter activity", "id": "GO:0015489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015489", "evidence": [ { "database": "UniProtKB", "id": "P33413", "url": "https://www.uniprot.org/uniprotkb/P33413" } ], "pmid": "" }, { "name": "urea transmembrane transporter activity", "id": "GO:0015204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015204", "evidence": [ { "database": "UniProtKB", "id": "P33413", "url": "https://www.uniprot.org/uniprotkb/P33413" } ], "pmid": "" }, { "name": "spermidine transmembrane transporter activity", "id": "GO:0015606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015606", "evidence": [ { "database": "UniProtKB", "id": "P33413", "url": "https://www.uniprot.org/uniprotkb/P33413" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33413-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Thr250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "Q03407-1", "kinase_gene_name": "PKH1", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "17218313", "url": "https://glygen.org/publication/PubMed/17218313" } ] }, { "kinase_uniprot_canonical_ac": "Q12236-1", "kinase_gene_name": "PKH2", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "17218313", "url": "https://glygen.org/publication/PubMed/17218313" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "17218313", "url": "https://glygen.org/publication/PubMed/17218313" } ] } ] }, { "uniprot_canonical_ac": "P33413-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Ser251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "Q03407-1", "kinase_gene_name": "PKH1", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "17218313", "url": "https://glygen.org/publication/PubMed/17218313" } ] }, { "kinase_uniprot_canonical_ac": "Q12236-1", "kinase_gene_name": "PKH2", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "17218313", "url": "https://glygen.org/publication/PubMed/17218313" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "17218313", "url": "https://glygen.org/publication/PubMed/17218313" } ] } ] }, { "uniprot_canonical_ac": "P33413-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Thr684", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "Q03407-1", "kinase_gene_name": "PKH1", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "17218313", "url": "https://glygen.org/publication/PubMed/17218313" } ] }, { "kinase_uniprot_canonical_ac": "Q12236-1", "kinase_gene_name": "PKH2", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "17218313", "url": "https://glygen.org/publication/PubMed/17218313" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "17218313", "url": "https://glygen.org/publication/PubMed/17218313" } ] } ] }, { "uniprot_canonical_ac": "P33413-1", "start_pos": "714", "end_pos": "714", "site_lbl": "Thr714", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P33413-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Ser715", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001008", "url": "https://www.yeastgenome.org/locus/S000001008" }, { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P33413-1", "start_pos": "718", "end_pos": "718", "site_lbl": "Ser718", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33413", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33413" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001008", "url": "https://www.yeastgenome.org/locus/S000001008" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] } ], "record_id": "P33413-1" }, { "uniprot_canonical_ac": "P33418-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33418", "url": "https://www.uniprot.org/uniprotkb/P33418" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1100, "chemical_mass": 126820.0, "gene_names": "LOS1;LOS1", "protein_name": "Exportin-T", "disease": [], "biological_process": [ { "name": "tRNA re-export from nucleus", "id": "GO:0071528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071528", "evidence": [ { "database": "UniProtKB", "id": "P33418", "url": "https://www.uniprot.org/uniprotkb/P33418" } ], "pmid": "" }, { "name": "tRNA export from nucleus", "id": "GO:0006409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006409", "evidence": [ { "database": "UniProtKB", "id": "P33418", "url": "https://www.uniprot.org/uniprotkb/P33418" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33418", "url": "https://www.uniprot.org/uniprotkb/P33418" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P33418", "url": "https://www.uniprot.org/uniprotkb/P33418" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "P33418", "url": "https://www.uniprot.org/uniprotkb/P33418" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "P33418", "url": "https://www.uniprot.org/uniprotkb/P33418" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "P33418", "url": "https://www.uniprot.org/uniprotkb/P33418" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33418-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Ser279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001688", "url": "https://www.yeastgenome.org/locus/S000001688" }, { "database": "iPTMnet", "id": "P33418", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33418" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P33418-1" }, { "uniprot_canonical_ac": "P33419-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 253, "chemical_mass": 29280.0, "gene_names": "SPC29;LPH3W;LPH3;NIP29;SPC29", "protein_name": "Spindle pole component 29", "disease": [], "biological_process": [ { "name": "regulation of microtubule nucleation", "id": "GO:0010968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010968", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" } ], "pmid": "" }, { "name": "mitotic spindle pole body duplication", "id": "GO:1903087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903087", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" } ], "pmid": "" }, { "name": "central plaque of spindle pole body", "id": "GO:0005823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005823", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" } ], "pmid": "" }, { "name": "central plaque of mitotic spindle pole body", "id": "GO:0061493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061493", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33419-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Thr119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Thr159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "20368617", "url": "https://glygen.org/publication/PubMed/20368617" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "20368617", "url": "https://glygen.org/publication/PubMed/20368617" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Thr18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "20368617", "url": "https://glygen.org/publication/PubMed/20368617" }, { "database": "PubMed", "id": "30044722", "url": "https://glygen.org/publication/PubMed/30044722" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Thr240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19269975", "url": "https://glygen.org/publication/PubMed/19269975" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20368617", "url": "https://glygen.org/publication/PubMed/20368617" }, { "database": "PubMed", "id": "30044722", "url": "https://glygen.org/publication/PubMed/30044722" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Lead to defects in spindle pole body assembly.", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" }, { "database": "PubMed", "id": "19269975", "url": "https://glygen.org/publication/PubMed/19269975" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Ser249", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Ser250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Thr42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33419", "url": "https://www.uniprot.org/uniprotkb/P33419" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Thr67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33419-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006045", "url": "https://www.yeastgenome.org/locus/S000006045" }, { "database": "iPTMnet", "id": "P33419", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33419" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33419-1" }, { "uniprot_canonical_ac": "P33420-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 868, "chemical_mass": 100290.0, "gene_names": "NIP100;NIP100;NIP80;PAC13", "protein_name": "Protein NIP100", "disease": [], "cellular_component": [ { "name": "cell tip", "id": "GO:0051286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051286", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "dynactin complex", "id": "GO:0005869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005869", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "microtubule associated complex", "id": "GO:0005875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005875", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" }, { "name": "nuclear migration involved in conjugation with cellular fusion", "id": "GO:0000743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000743", "evidence": [ { "database": "UniProtKB", "id": "P33420", "url": "https://www.uniprot.org/uniprotkb/P33420" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33420-1", "start_pos": "761", "end_pos": "761", "site_lbl": "Ser761", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 761, "start_aa": "Ser", "end_pos": 761, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser761", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P33420", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P33420" } ] } ] }, { "uniprot_canonical_ac": "P33420-1", "start_pos": "598", "end_pos": "598", "site_lbl": "Ser598", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006095", "url": "https://www.yeastgenome.org/locus/S000006095" }, { "database": "iPTMnet", "id": "P33420", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33420" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33420-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Ser599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006095", "url": "https://www.yeastgenome.org/locus/S000006095" }, { "database": "iPTMnet", "id": "P33420", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33420" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33420-1" }, { "uniprot_canonical_ac": "P33421-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 198, "chemical_mass": 22068.0, "gene_names": "SDH3;CYB3;SDH3;YKL4", "protein_name": "Succinate dehydrogenase [ubiquinone] cytochrome b subunit, mitochondrial", "disease": [ { "disease_id": "DOID:0050773", "name": "paraganglioma", "description": "A pheochromocytoma that arises in extraadrenal sympathetic ganglia.", "url": "https://disease-ontology.org/term/DOID:0050773", "evidence": [ { "id": "0050773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050773" } ], "weight": 0.0 }, { "disease_id": "DOID:0061218", "name": "pheochromocytoma/paraganglioma syndrome 3", "description": "A paraganglioma characterized by the development of neuroendocrine tumors, usually in adulthood that has material_basis_in heterozygous mutation in the SDHC gene.", "url": "https://disease-ontology.org/term/DOID:0061218", "evidence": [ { "id": "0061218", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061218" } ], "weight": 0.0 }, { "disease_id": "DOID:0080533", "name": "Carney-Stratakis syndrome", "description": "A syndrome that is characterized by the presence of multicentric paragangliomas and multifocal gastrointestinal stromal sarcoma tumors.", "url": "https://disease-ontology.org/term/DOID:0080533", "evidence": [ { "id": "0080533", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080533" } ], "weight": 0.0 }, { "disease_id": "DOID:3652", "name": "Leigh disease", "description": "A cytochrome-c oxidase deficiency disease characterized by progressive loss of mental and movement abilities. Symptoms usually begin between ages of three months and two years and include loss of appetite, vomiting, irritability and seizure activity.", "url": "https://disease-ontology.org/term/DOID:3652", "evidence": [ { "id": "3652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3652" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:9253", "name": "gastrointestinal stromal tumor", "description": "", "url": "https://disease-ontology.org/term/DOID:9253", "evidence": [ { "id": "9253", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9253" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" }, { "name": "TIM22 mitochondrial import inner membrane insertion complex", "id": "GO:0042721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042721", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" }, { "name": "respiratory chain complex II (succinate dehydrogenase)", "id": "GO:0045273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045273", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" }, { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" }, { "name": "mitochondrial electron transport, succinate to ubiquinone", "id": "GO:0006121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006121", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" }, { "name": "cellular respiration", "id": "GO:0045333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045333", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" } ], "molecular_function": [ { "name": "electron transfer activity", "id": "GO:0009055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009055", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" }, { "name": "quinone binding", "id": "GO:0048038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048038", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33421-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Phe153", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "V", "comment": "Decreases quinone reductase activity. Little effect on complex assembly.", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" }, { "database": "PubMed", "id": "10446163", "url": "https://glygen.org/publication/PubMed/10446163" } ] } ] }, { "uniprot_canonical_ac": "P33421-1", "start_pos": "156", "end_pos": "156", "site_lbl": "His156", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Decreases SDH cytochrome b content.", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" }, { "database": "PubMed", "id": "14672930", "url": "https://glygen.org/publication/PubMed/14672930" } ] } ] }, { "uniprot_canonical_ac": "P33421-1", "start_pos": "163", "end_pos": "163", "site_lbl": "His163", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Q", "comment": "Decreases quinone reductase activity. Little effect on complex assembly.", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" }, { "database": "PubMed", "id": "10446163", "url": "https://glygen.org/publication/PubMed/10446163" } ] } ] }, { "uniprot_canonical_ac": "P33421-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Trp166", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "R", "comment": "Decreases quinone reductase activity. Little effect on complex assembly.", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" }, { "database": "PubMed", "id": "10446163", "url": "https://glygen.org/publication/PubMed/10446163" } ] } ] }, { "uniprot_canonical_ac": "P33421-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Asp167", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "V", "comment": "Reduces SDHFAD content. Probably impairs complex assembly.", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" } ] } ] }, { "uniprot_canonical_ac": "P33421-1", "start_pos": "96", "end_pos": "96", "site_lbl": "His96", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Decreases quinone reductase activity.", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" }, { "database": "PubMed", "id": "14672930", "url": "https://glygen.org/publication/PubMed/14672930" } ] }, { "sequence_org": "H", "sequence_mut": "D", "comment": "Decreases quinone reductase activity.", "evidence": [ { "database": "UniProtKB", "id": "P33421", "url": "https://www.uniprot.org/uniprotkb/P33421" }, { "database": "PubMed", "id": "14672930", "url": "https://glygen.org/publication/PubMed/14672930" } ] } ] } ], "record_id": "P33421-1" }, { "uniprot_canonical_ac": "P33441-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 392, "chemical_mass": 44996.0, "gene_names": "MFT1;MFT1;MFT52", "protein_name": "THO complex subunit MFT1", "disease": [], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" } ], "pmid": "" } ], "cellular_component": [ { "name": "THO complex part of transcription export complex", "id": "GO:0000445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000445", "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" } ], "pmid": "" }, { "name": "nucleoplasmic THO complex", "id": "GO:0000446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000446", "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33441-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Tyr264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33441", "url": "https://www.uniprot.org/uniprotkb/P33441" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Ser281", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Ser297", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "333", "end_pos": "333", "site_lbl": "Ser333", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Ser368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Ser371", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "378", "end_pos": "378", "site_lbl": "Thr378", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Thr379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "380", "end_pos": "380", "site_lbl": "Ser380", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Ser383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Ser385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "386", "end_pos": "386", "site_lbl": "Ser386", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Ser387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33441-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004527", "url": "https://www.yeastgenome.org/locus/S000004527" }, { "database": "iPTMnet", "id": "P33441", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33441" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P33441-1" }, { "uniprot_canonical_ac": "P33442-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33442", "url": "https://www.uniprot.org/uniprotkb/P33442" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 255, "chemical_mass": 28743.0, "gene_names": "RPS1A;L9753.9;PLC1;RP10A;RPS10A;RPS1A", "protein_name": "Small ribosomal subunit protein eS1A", "disease": [ { "disease_id": "DOID:0060036", "name": "intrinsic cardiomyopathy", "description": "A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause.", "url": "https://disease-ontology.org/term/DOID:0060036", "evidence": [ { "id": "0060036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060036" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P33442", "url": "https://www.uniprot.org/uniprotkb/P33442" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P33442", "url": "https://www.uniprot.org/uniprotkb/P33442" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P33442", "url": "https://www.uniprot.org/uniprotkb/P33442" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P33442", "url": "https://www.uniprot.org/uniprotkb/P33442" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P33442", "url": "https://www.uniprot.org/uniprotkb/P33442" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "P33442", "url": "https://www.uniprot.org/uniprotkb/P33442" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P33442", "url": "https://www.uniprot.org/uniprotkb/P33442" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33442-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Thr129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Tyr133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Ser154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ser159", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Ser169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Ser236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Thr245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33442", "url": "https://www.uniprot.org/uniprotkb/P33442" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Thr254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33442", "url": "https://www.uniprot.org/uniprotkb/P33442" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Thr46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Thr52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33442-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33442", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33442" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000004433", "url": "https://www.yeastgenome.org/locus/S000004433" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P33442-1" }, { "uniprot_canonical_ac": "P33734-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 552, "chemical_mass": 61068.0, "gene_names": "HIS7;HIS7;YBR1640", "protein_name": "Imidazole glycerol phosphate synthase hisHF", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" } ], "pmid": "" } ], "molecular_function": [ { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" } ], "pmid": "" }, { "name": "glutaminase activity", "id": "GO:0004359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004359", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" } ], "pmid": "" }, { "name": "imidazoleglycerol-phosphate synthase activity", "id": "GO:0000107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000107", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" } ], "pmid": "" } ], "biological_process": [ { "name": "L-histidine biosynthetic process", "id": "GO:0000105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000105", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33734-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Tyr173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000452", "url": "https://www.yeastgenome.org/locus/S000000452" }, { "database": "iPTMnet", "id": "P33734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33734" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33734-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33734" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000452", "url": "https://www.yeastgenome.org/locus/S000000452" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33734-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Ser213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000452", "url": "https://www.yeastgenome.org/locus/S000000452" }, { "database": "iPTMnet", "id": "P33734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33734" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33734-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Ser268", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000452", "url": "https://www.yeastgenome.org/locus/S000000452" }, { "database": "iPTMnet", "id": "P33734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33734" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33734-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000452", "url": "https://www.yeastgenome.org/locus/S000000452" }, { "database": "iPTMnet", "id": "P33734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33734" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33734-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33734" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000452", "url": "https://www.yeastgenome.org/locus/S000000452" } ] } ] }, { "uniprot_canonical_ac": "P33734-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000452", "url": "https://www.yeastgenome.org/locus/S000000452" }, { "database": "iPTMnet", "id": "P33734", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33734" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33734-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Arg239", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "1000-fold decrease in catalytic efficiency. Uncoupling of glutaminase activity from the cyclase activity.", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" }, { "database": "PubMed", "id": "12795596", "url": "https://glygen.org/publication/PubMed/12795596" } ] }, { "sequence_org": "R", "sequence_mut": "H", "comment": "1000-fold decrease in catalytic efficiency. Uncoupling of glutaminase activity from the cyclase activity.", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" }, { "database": "PubMed", "id": "12795596", "url": "https://glygen.org/publication/PubMed/12795596" } ] }, { "sequence_org": "R", "sequence_mut": "K", "comment": "1000-fold decrease in catalytic efficiency. Uncoupling of glutaminase activity from the cyclase activity.", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" }, { "database": "PubMed", "id": "12795596", "url": "https://glygen.org/publication/PubMed/12795596" } ] } ] }, { "uniprot_canonical_ac": "P33734-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Lys258", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "No activity. Uncoupling of glutaminase activity from the cyclase activity.", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" }, { "database": "PubMed", "id": "12795596", "url": "https://glygen.org/publication/PubMed/12795596" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Small reduction of activity.", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" }, { "database": "PubMed", "id": "12795596", "url": "https://glygen.org/publication/PubMed/12795596" } ] } ] }, { "uniprot_canonical_ac": "P33734-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Lys360", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Almost no effect on activity.", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" }, { "database": "PubMed", "id": "12795596", "url": "https://glygen.org/publication/PubMed/12795596" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Almost no effect on activity.", "evidence": [ { "database": "UniProtKB", "id": "P33734", "url": "https://www.uniprot.org/uniprotkb/P33734" }, { "database": "PubMed", "id": "12795596", "url": "https://glygen.org/publication/PubMed/12795596" } ] } ] } ], "record_id": "P33734-1" }, { "uniprot_canonical_ac": "P33748-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 704, "chemical_mass": 77861.0, "gene_names": "MSN2;MSN2;YM9532.02C", "protein_name": "Zinc finger protein MSN2", "disease": [], "biological_process": [ { "name": "cellular hypotonic response", "id": "GO:0071476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071476", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to cold", "id": "GO:0070417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070417", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to caloric restriction", "id": "GO:0061433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061433", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to alkaline pH", "id": "GO:0071469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071469", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to ethanol", "id": "GO:0071361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071361", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to nitrosative stress", "id": "GO:0071500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071500", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to acidic pH", "id": "GO:0071468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071468", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to hydrostatic pressure", "id": "GO:0071464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071464", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to zinc ion starvation", "id": "GO:0034224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034224", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to arsenic-containing substance", "id": "GO:0071243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071243", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to freezing", "id": "GO:0071497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071497", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cellular response to salt", "id": "GO:1902075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902075", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33748-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "28330760", "url": "https://glygen.org/publication/PubMed/28330760" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Ser208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Ser288", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23275436", "url": "https://glygen.org/publication/PubMed/23275436" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Ser304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "23275436", "url": "https://glygen.org/publication/PubMed/23275436" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Ser308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "427", "end_pos": "427", "site_lbl": "Ser427", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "428", "end_pos": "428", "site_lbl": "Ser428", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "432", "end_pos": "432", "site_lbl": "Ser432", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Thr434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Ser441", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "451", "end_pos": "451", "site_lbl": "Ser451", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23275436", "url": "https://glygen.org/publication/PubMed/23275436" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Ser458", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Tyr461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "582", "end_pos": "582", "site_lbl": "Ser582", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "16281053", "url": "https://glygen.org/publication/PubMed/16281053" }, { "database": "PubMed", "id": "24981510", "url": "https://glygen.org/publication/PubMed/24981510" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Ser620", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18375619", "url": "https://glygen.org/publication/PubMed/18375619" }, { "database": "PubMed", "id": "24981510", "url": "https://glygen.org/publication/PubMed/24981510" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "625", "end_pos": "625", "site_lbl": "Ser625", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "24981510", "url": "https://glygen.org/publication/PubMed/24981510" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "627", "end_pos": "627", "site_lbl": "Thr627", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "629", "end_pos": "629", "site_lbl": "Ser629", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Ser632", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "633", "end_pos": "633", "site_lbl": "Ser633", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33748", "url": "https://www.uniprot.org/uniprotkb/P33748" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "24981510", "url": "https://glygen.org/publication/PubMed/24981510" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23275436", "url": "https://glygen.org/publication/PubMed/23275436" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33748-1", "start_pos": "638", "end_pos": "638", "site_lbl": "Ser638", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33748", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33748" }, { "database": "PubMed", "id": "28330760", "url": "https://glygen.org/publication/PubMed/28330760" }, { "database": "SGD", "id": "S000004640", "url": "https://www.yeastgenome.org/locus/S000004640" } ] } ] } ], "record_id": "P33748-1" }, { "uniprot_canonical_ac": "P33751-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33751", "url": "https://www.uniprot.org/uniprotkb/P33751" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 242, "chemical_mass": 26733.0, "gene_names": "PAD1;PAD1;POF1", "protein_name": "Flavin prenyltransferase PAD1, mitochondrial", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P33751", "url": "https://www.uniprot.org/uniprotkb/P33751" } ], "pmid": "" }, { "name": "carboxy-lyase activity", "id": "GO:0016831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016831", "evidence": [ { "database": "UniProtKB", "id": "P33751", "url": "https://www.uniprot.org/uniprotkb/P33751" } ], "pmid": "" }, { "name": "flavin prenyltransferase activity", "id": "GO:0106141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106141", "evidence": [ { "database": "UniProtKB", "id": "P33751", "url": "https://www.uniprot.org/uniprotkb/P33751" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P33751", "url": "https://www.uniprot.org/uniprotkb/P33751" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P33751", "url": "https://www.uniprot.org/uniprotkb/P33751" } ], "pmid": "" }, { "name": "cinnamic acid catabolic process", "id": "GO:0046281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046281", "evidence": [ { "database": "UniProtKB", "id": "P33751", "url": "https://www.uniprot.org/uniprotkb/P33751" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P33751-1" }, { "uniprot_canonical_ac": "P33753-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33753", "url": "https://www.uniprot.org/uniprotkb/P33753" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 639, "chemical_mass": 72852.0, "gene_names": "TRM2;NUC2;NUD1;RNC1;TRM2", "protein_name": "tRNA (uracil(54)-C(5))-methyltransferase", "disease": [], "biological_process": [ { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "P33753", "url": "https://www.uniprot.org/uniprotkb/P33753" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "P33753", "url": "https://www.uniprot.org/uniprotkb/P33753" } ], "pmid": "" } ], "molecular_function": [ { "name": "single-stranded DNA endodeoxyribonuclease activity", "id": "GO:0000014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000014", "evidence": [ { "database": "UniProtKB", "id": "P33753", "url": "https://www.uniprot.org/uniprotkb/P33753" } ], "pmid": "" }, { "name": "double-stranded DNA 5'-3' DNA exonuclease activity", "id": "GO:0051908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051908", "evidence": [ { "database": "UniProtKB", "id": "P33753", "url": "https://www.uniprot.org/uniprotkb/P33753" } ], "pmid": "" }, { "name": "tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent", "id": "GO:0030697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030697", "evidence": [ { "database": "UniProtKB", "id": "P33753", "url": "https://www.uniprot.org/uniprotkb/P33753" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33753-1", "start_pos": "92", "end_pos": "92", "site_lbl": "Ser92", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33753", "url": "https://www.uniprot.org/uniprotkb/P33753" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33753", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33753" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001764", "url": "https://www.yeastgenome.org/locus/S000001764" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33753-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Ser93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P33753", "url": "https://www.uniprot.org/uniprotkb/P33753" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P33753", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33753" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001764", "url": "https://www.yeastgenome.org/locus/S000001764" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33753-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Thr96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33753", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33753" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001764", "url": "https://www.yeastgenome.org/locus/S000001764" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P33753-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001764", "url": "https://www.yeastgenome.org/locus/S000001764" }, { "database": "iPTMnet", "id": "P33753", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33753" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33753-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Gly498", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Unable to methylate tRNA.", "evidence": [ { "database": "UniProtKB", "id": "P33753", "url": "https://www.uniprot.org/uniprotkb/P33753" }, { "database": "PubMed", "id": "12003492", "url": "https://glygen.org/publication/PubMed/12003492" } ] } ] }, { "uniprot_canonical_ac": "P33753-1", "start_pos": "591", "end_pos": "591", "site_lbl": "Cys591", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Unable to methylate tRNA.", "evidence": [ { "database": "UniProtKB", "id": "P33753", "url": "https://www.uniprot.org/uniprotkb/P33753" }, { "database": "PubMed", "id": "12003492", "url": "https://glygen.org/publication/PubMed/12003492" } ] } ] } ], "record_id": "P33753-1" }, { "uniprot_canonical_ac": "P33767-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33767", "url": "https://www.uniprot.org/uniprotkb/P33767" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 430, "chemical_mass": 49392.0, "gene_names": "WBP1;WBP1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1", "disease": [ { "disease_id": "DOID:0080569", "name": "congenital disorder of glycosylation Ir", "description": "A congenital disorder of glycosylation I that is characterized by failure to thrive, developmental delay, hypotonia, strabismus and hepatic dysfunction and has_material_basis_in compound heterozygous mutation in the DDOST gene on chromosome 1p36.", "url": "https://disease-ontology.org/term/DOID:0080569", "evidence": [ { "id": "0080569", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080569" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P33767", "url": "https://www.uniprot.org/uniprotkb/P33767" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P33767", "url": "https://www.uniprot.org/uniprotkb/P33767" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P33767", "url": "https://www.uniprot.org/uniprotkb/P33767" } ], "pmid": "" }, { "name": "oligosaccharyltransferase complex", "id": "GO:0008250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008250", "evidence": [ { "database": "UniProtKB", "id": "P33767", "url": "https://www.uniprot.org/uniprotkb/P33767" } ], "pmid": "" } ], "molecular_function": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "P33767", "url": "https://www.uniprot.org/uniprotkb/P33767" } ], "pmid": "" } ], "biological_process": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "P33767", "url": "https://www.uniprot.org/uniprotkb/P33767" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33767-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Asn332", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=7OCI&bu=0&command=select+.G:332;+center+selection;+zoom+selection" }, "start_pos": 332, "start_aa": "Asn", "end_pos": 332, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn332", "evidence": [ { "id": "P33767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P33767#ptm_processing" }, { "id": "29301962", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29301962" }, { "id": "7OCI", "database": "PDB", "url": "https://www.rcsb.org/structure/7OCI" }, { "id": "7OCI", "database": "PDB", "url": "https://www.rcsb.org/structure/7OCI" }, { "id": "6EZN", "database": "PDB", "url": "https://www.rcsb.org/structure/6EZN" }, { "id": "6EZN", "database": "PDB", "url": "https://www.rcsb.org/structure/6EZN" }, { "id": "7OCI|G|332", "database": "", "url": "" }, { "id": "6EZN|G|332", "database": "", "url": "" } ] } ] }, { "uniprot_canonical_ac": "P33767-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Asn60", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=6C26&bu=0&command=select+.B:60;+center+selection;+zoom+selection" }, "start_pos": 60, "start_aa": "Asn", "end_pos": 60, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn60", "evidence": [ { "id": "P33767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P33767#ptm_processing" }, { "id": "29301962", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29301962" }, { "id": "6C26", "database": "PDB", "url": "https://www.rcsb.org/structure/6C26" }, { "id": "6C26", "database": "PDB", "url": "https://www.rcsb.org/structure/6C26" }, { "id": "7OCI", "database": "PDB", "url": "https://www.rcsb.org/structure/7OCI" }, { "id": "7OCI", "database": "PDB", "url": "https://www.rcsb.org/structure/7OCI" }, { "id": "6C26|B|60", "database": "", "url": "" }, { "id": "7OCI|G|60", "database": "", "url": "" } ] } ] } ], "record_id": "P33767-1" }, { "uniprot_canonical_ac": "P33775-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 817, "chemical_mass": 92675.0, "gene_names": "PMT1;D2390;PMT1", "protein_name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 1", "disease": [], "molecular_function": [ { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase activity", "id": "GO:0004169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004169", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "pmid": "" }, { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex", "id": "GO:0097583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097583", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "pmid": "" }, { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex", "id": "GO:0097582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097582", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "pmid": "" } ], "biological_process": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "pmid": "" }, { "name": "protein exit from endoplasmic reticulum", "id": "GO:0032527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032527", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "pmid": "" }, { "name": "regulation of endoplasmic reticulum unfolded protein response", "id": "GO:1900101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900101", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "pmid": "" }, { "name": "fungal-type cell wall biogenesis", "id": "GO:0009272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009272", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33775-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Asn390", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 390, "start_aa": "Asn", "end_pos": 390, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn390", "evidence": [ { "id": "P33775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P33775#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P33775-1", "start_pos": "513", "end_pos": "513", "site_lbl": "Asn513", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 513, "start_aa": "Asn", "end_pos": 513, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn513", "evidence": [ { "id": "P33775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P33775#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P33775-1", "start_pos": "743", "end_pos": "743", "site_lbl": "Asn743", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 743, "start_aa": "Asn", "end_pos": 743, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn743", "evidence": [ { "id": "P33775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P33775#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P33775-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Pro100", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "Moderately decreases complex formation with PMT2.", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" }, { "database": "PubMed", "id": "21956107", "url": "https://glygen.org/publication/PubMed/21956107" } ] } ] }, { "uniprot_canonical_ac": "P33775-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Arg138", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs complex formation with PMT2.", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" }, { "database": "PubMed", "id": "10764776", "url": "https://glygen.org/publication/PubMed/10764776" } ] } ] }, { "uniprot_canonical_ac": "P33775-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Leu408", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Reduces mannosyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" }, { "database": "PubMed", "id": "10764776", "url": "https://glygen.org/publication/PubMed/10764776" } ] } ] }, { "uniprot_canonical_ac": "P33775-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Arg64", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces mannosyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" }, { "database": "PubMed", "id": "10764776", "url": "https://glygen.org/publication/PubMed/10764776" } ] } ] }, { "uniprot_canonical_ac": "P33775-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Glu78", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Decreases substrate-binding and reduces mannosyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" }, { "database": "PubMed", "id": "21956107", "url": "https://glygen.org/publication/PubMed/21956107" }, { "database": "PubMed", "id": "10764776", "url": "https://glygen.org/publication/PubMed/10764776" } ] } ] }, { "uniprot_canonical_ac": "P33775-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Tyr88", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Moderately decreases complex formation with PMT2.", "evidence": [ { "database": "UniProtKB", "id": "P33775", "url": "https://www.uniprot.org/uniprotkb/P33775" }, { "database": "PubMed", "id": "21956107", "url": "https://glygen.org/publication/PubMed/21956107" } ] } ] } ], "record_id": "P33775-1" }, { "uniprot_canonical_ac": "P33891-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33891", "url": "https://www.uniprot.org/uniprotkb/P33891" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 701, "chemical_mass": 81167.0, "gene_names": "TIP20;TIP1;TIP20", "protein_name": "Protein transport protein TIP20", "disease": [ { "disease_id": "DOID:0080716", "name": "infantile liver failure syndrome", "description": "A syndrome that is characterized by acute liver failure, that occurs in the first year of life, which manifests with failure to thrive, hypotonia, moderate global developmental delay, seizures, abnormal liver function tests, microcytic anemia and elevated serum lactate.", "url": "https://disease-ontology.org/term/DOID:0080716", "evidence": [ { "id": "0080716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080716" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Dsl1/NZR complex", "id": "GO:0070939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070939", "evidence": [ { "database": "UniProtKB", "id": "P33891", "url": "https://www.uniprot.org/uniprotkb/P33891" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P33891", "url": "https://www.uniprot.org/uniprotkb/P33891" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P33891", "url": "https://www.uniprot.org/uniprotkb/P33891" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P33891", "url": "https://www.uniprot.org/uniprotkb/P33891" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P33891", "url": "https://www.uniprot.org/uniprotkb/P33891" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P33891", "url": "https://www.uniprot.org/uniprotkb/P33891" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "P33891", "url": "https://www.uniprot.org/uniprotkb/P33891" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "P33891", "url": "https://www.uniprot.org/uniprotkb/P33891" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33891-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Ser190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003113", "url": "https://www.yeastgenome.org/locus/S000003113" }, { "database": "iPTMnet", "id": "P33891", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33891" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33891-1", "start_pos": "584", "end_pos": "584", "site_lbl": "Ser584", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33891", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33891" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P33891-1", "start_pos": "693", "end_pos": "693", "site_lbl": "Tyr693", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P33891", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33891" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003113", "url": "https://www.yeastgenome.org/locus/S000003113" } ] } ] } ], "record_id": "P33891-1" }, { "uniprot_canonical_ac": "P33895-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 451, "chemical_mass": 52973.0, "gene_names": "NUF2;NUF2", "protein_name": "Kinetochore protein NUF2", "disease": [ { "disease_id": "DOID:0050610", "name": "oral cavity carcinoma in situ", "description": "An in situ carcinoma of the oral cavity that is located_in the epithelium. It is the most common cause of leukoplakia and associated with the development of squamous cell carcinoma.", "url": "https://disease-ontology.org/term/DOID:0050610", "evidence": [ { "id": "0050610", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050610" } ], "weight": 0.0 }, { "disease_id": "DOID:0080909", "name": "castration-resistant prostate carcinoma", "description": "A prostate carcinoma that is characterized by continued growth and spread despite the surgical removal of the testes or medical intervention to block androgen production.", "url": "https://disease-ontology.org/term/DOID:0080909", "evidence": [ { "id": "0080909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080909" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "kinetochore organization", "id": "GO:0051383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051383", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "meiotic chromosome segregation", "id": "GO:0045132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045132", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" } ], "cellular_component": [ { "name": "Ndc80 complex", "id": "GO:0031262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031262", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "condensed chromosome, centromeric region", "id": "GO:0000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000779", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P33895-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005430", "url": "https://www.yeastgenome.org/locus/S000005430" }, { "database": "iPTMnet", "id": "P33895", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P33895" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P33895-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Thr338", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "P", "comment": "Temperature-sensitive.", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" }, { "database": "PubMed", "id": "8188751", "url": "https://glygen.org/publication/PubMed/8188751" } ] } ] }, { "uniprot_canonical_ac": "P33895-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ile340", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "K", "comment": "Temperature-sensitive.", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" }, { "database": "PubMed", "id": "8188751", "url": "https://glygen.org/publication/PubMed/8188751" } ] } ] }, { "uniprot_canonical_ac": "P33895-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Tyr383", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "C", "comment": "Temperature-sensitive.", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" }, { "database": "PubMed", "id": "8188751", "url": "https://glygen.org/publication/PubMed/8188751" } ] } ] }, { "uniprot_canonical_ac": "P33895-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Leu410", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "Temperature-sensitive.", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" }, { "database": "PubMed", "id": "8188751", "url": "https://glygen.org/publication/PubMed/8188751" } ] } ] }, { "uniprot_canonical_ac": "P33895-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Lys441", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "I", "comment": "Temperature-sensitive.", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" }, { "database": "PubMed", "id": "8188751", "url": "https://glygen.org/publication/PubMed/8188751" } ] } ] }, { "uniprot_canonical_ac": "P33895-1", "start_pos": "446", "end_pos": "446", "site_lbl": "Met446", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "L", "comment": "Temperature-sensitive.", "evidence": [ { "database": "UniProtKB", "id": "P33895", "url": "https://www.uniprot.org/uniprotkb/P33895" }, { "database": "PubMed", "id": "8188751", "url": "https://glygen.org/publication/PubMed/8188751" } ] } ] } ], "record_id": "P33895-1" }, { "uniprot_canonical_ac": "P34072-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 584, "chemical_mass": 65643.0, "gene_names": "MKS1;LYS80;MKS1;N2344;N2347", "protein_name": "Negative regulator of RAS-cAMP pathway", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" } ], "pmid": "" }, { "name": "regulation of nitrogen utilization", "id": "GO:0006808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006808", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" } ], "pmid": "" }, { "name": "mitochondria-nucleus signaling pathway", "id": "GO:0031930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031930", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" } ], "pmid": "" }, { "name": "regulation of pseudohyphal growth", "id": "GO:2000220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000220", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34072-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Ser140", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 140, "start_aa": "Ser", "end_pos": 140, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser140", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34072", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34072" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 146, "start_aa": "Ser", "end_pos": 146, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser146", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34072", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34072" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Ser349", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 349, "start_aa": "Ser", "end_pos": 349, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser349", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34072", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34072" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Ser350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 350, "start_aa": "Ser", "end_pos": 350, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser350", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34072", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34072" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 352, "start_aa": "Ser", "end_pos": 352, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser352", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34072", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34072" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 353, "start_aa": "Ser", "end_pos": 353, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser353", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34072", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34072" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 359, "start_aa": "Ser", "end_pos": 359, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser359", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34072", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34072" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 362, "start_aa": "Ser", "end_pos": 362, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser362", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34072", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34072" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Thr401", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 401, "start_aa": "Thr", "end_pos": 401, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr401", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Thr128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ser164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Thr165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Thr166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Ser237", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Thr241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Ser247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Ser250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Ser251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Ser264", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Tyr265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Ser274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Ser276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Thr347", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Ser419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Ser429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "440", "end_pos": "440", "site_lbl": "Ser440", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "442", "end_pos": "442", "site_lbl": "Ser442", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "453", "end_pos": "453", "site_lbl": "Ser453", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Ser466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Ser487", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Ser507", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "509", "end_pos": "509", "site_lbl": "Thr509", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Ser518", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34072", "url": "https://www.uniprot.org/uniprotkb/P34072" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Ser523", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Ser538", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Thr553", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "554", "end_pos": "554", "site_lbl": "Ser554", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "558", "end_pos": "558", "site_lbl": "Ser558", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34072-1", "start_pos": "579", "end_pos": "579", "site_lbl": "Ser579", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005020", "url": "https://www.yeastgenome.org/locus/S000005020" }, { "database": "iPTMnet", "id": "P34072", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34072" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P34072-1" }, { "uniprot_canonical_ac": "P34077-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 839, "chemical_mass": 96174.0, "gene_names": "NIC96;NIC96", "protein_name": "Nucleoporin NIC96", "disease": [ { "disease_id": "DOID:0080387", "name": "nephrotic syndrome type 12", "description": "A familial nephrotic syndrome characterized by early childhood onset of steroid-resistant progressive renal failure with focal segmental glomerulosclerosis that has_material_basis_in homozygous or compound heterozygous mutation in the NUP93 gene on chromosome 16q13.", "url": "https://disease-ontology.org/term/DOID:0080387", "evidence": [ { "id": "0080387", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080387" } ], "weight": 0.0 } ], "biological_process": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" }, { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" }, { "name": "nuclear pore organization", "id": "GO:0006999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006999", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore nuclear basket", "id": "GO:0044615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044615", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" }, { "name": "nuclear pore linkers", "id": "GO:0044612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044612", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "P34077", "url": "https://www.uniprot.org/uniprotkb/P34077" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34077-1", "start_pos": "567", "end_pos": "567", "site_lbl": "Thr567", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 567, "start_aa": "Thr", "end_pos": 567, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr567", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P34077-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34077" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001898", "url": "https://www.yeastgenome.org/locus/S000001898" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34077-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34077" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001898", "url": "https://www.yeastgenome.org/locus/S000001898" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34077-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001898", "url": "https://www.yeastgenome.org/locus/S000001898" }, { "database": "iPTMnet", "id": "P34077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34077-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34077" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001898", "url": "https://www.yeastgenome.org/locus/S000001898" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34077-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34077" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P34077-1", "start_pos": "694", "end_pos": "694", "site_lbl": "Ser694", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001898", "url": "https://www.yeastgenome.org/locus/S000001898" }, { "database": "iPTMnet", "id": "P34077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34077" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P34077-1" }, { "uniprot_canonical_ac": "P34110-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 944, "chemical_mass": 109142.0, "gene_names": "VPS35;ENV1;GRD9;J0580;VPS35;VPT7", "protein_name": "Vacuolar protein sorting-associated protein 35", "disease": [ { "disease_id": "DOID:0060897", "name": "Parkinson's disease 17", "description": "A late-onset Parkinson disease that has_material_basis_in heterozygous mutation in the VPS35 gene on chromosome 16q13.", "url": "https://disease-ontology.org/term/DOID:0060897", "evidence": [ { "id": "0060897", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060897" } ], "weight": 0.0 }, { "disease_id": "DOID:1319", "name": "brain cancer", "description": "A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain.", "url": "https://disease-ontology.org/term/DOID:1319", "evidence": [ { "id": "1319", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1319" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of endoplasmic reticulum unfolded protein response", "id": "GO:1900102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900102", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "protein retention in Golgi apparatus", "id": "GO:0045053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045053", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" } ], "cellular_component": [ { "name": "retromer, cargo-selective complex", "id": "GO:0030906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030906", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" }, { "name": "CROP complex", "id": "GO:0170071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170071", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34110-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34110-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Tyr3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P34110-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34110-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Thr410", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34110-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Ser488", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003690", "url": "https://www.yeastgenome.org/locus/S000003690" }, { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34110-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Ser507", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003690", "url": "https://www.yeastgenome.org/locus/S000003690" }, { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34110-1", "start_pos": "844", "end_pos": "844", "site_lbl": "Thr844", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003690", "url": "https://www.yeastgenome.org/locus/S000003690" }, { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P34110-1", "start_pos": "846", "end_pos": "846", "site_lbl": "Ser846", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "SGD", "id": "S000003690", "url": "https://www.yeastgenome.org/locus/S000003690" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P34110-1", "start_pos": "848", "end_pos": "848", "site_lbl": "Ser848", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "SGD", "id": "S000003690", "url": "https://www.yeastgenome.org/locus/S000003690" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34110-1", "start_pos": "862", "end_pos": "862", "site_lbl": "Ser862", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003690", "url": "https://www.yeastgenome.org/locus/S000003690" }, { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34110-1", "start_pos": "868", "end_pos": "868", "site_lbl": "Ser868", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34110", "url": "https://www.uniprot.org/uniprotkb/P34110" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34110" }, { "database": "SGD", "id": "S000003690", "url": "https://www.yeastgenome.org/locus/S000003690" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P34110-1" }, { "uniprot_canonical_ac": "P34111-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1160, "chemical_mass": 132108.0, "gene_names": "TFC3;FUN24;TFC3;TSV115", "protein_name": "Transcription factor tau 138 kDa subunit", "disease": [], "cellular_component": [ { "name": "transcription factor TFIIIC complex", "id": "GO:0000127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000127", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" } ], "pmid": "" } ], "biological_process": [ { "name": "5S class rRNA transcription by RNA polymerase III", "id": "GO:0042791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042791", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" } ], "pmid": "" }, { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34111-1", "start_pos": "1065", "end_pos": "1065", "site_lbl": "Ser1065", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Ser268", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Ser270", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Ser275", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "378", "end_pos": "378", "site_lbl": "Ser378", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Ser434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Thr436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "493", "end_pos": "493", "site_lbl": "Ser493", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Thr494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Ser522", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Ser526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Ser529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "546", "end_pos": "546", "site_lbl": "Ser546", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "881", "end_pos": "881", "site_lbl": "Ser881", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "918", "end_pos": "918", "site_lbl": "Ser918", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000001", "url": "https://www.yeastgenome.org/locus/S000000001" }, { "database": "iPTMnet", "id": "P34111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34111-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Gly349", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "In TSV115; thermosensitive. Level of TFIIIC and its affinity for tDNA reduced. tDNA binding activity very sensitive to mild heat treatments, and TFIIIC-DNA interaction inhibited at moderate salt concentrations.", "evidence": [ { "database": "UniProtKB", "id": "P34111", "url": "https://www.uniprot.org/uniprotkb/P34111" }, { "database": "PubMed", "id": "8083243", "url": "https://glygen.org/publication/PubMed/8083243" } ] } ] } ], "record_id": "P34111-1" }, { "uniprot_canonical_ac": "P34160-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 861, "chemical_mass": 100018.0, "gene_names": "STO1;CBC1;CBP80;GCR3;STO1;SUT1;YM8564.07;YM9553.01", "protein_name": "Nuclear cap-binding protein complex subunit 1", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "RNA cap binding", "id": "GO:0000339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000339", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "commitment complex", "id": "GO:0000243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000243", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "nuclear cap binding complex", "id": "GO:0005846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005846", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "response to osmotic stress", "id": "GO:0006970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006970", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "mRNA transcription by RNA polymerase II", "id": "GO:0042789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042789", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "7-methylguanosine mRNA capping", "id": "GO:0006370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006370", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "primary miRNA processing", "id": "GO:0031053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031053", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "P34160", "url": "https://www.uniprot.org/uniprotkb/P34160" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34160-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Ser531", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004732", "url": "https://www.yeastgenome.org/locus/S000004732" }, { "database": "iPTMnet", "id": "P34160", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P34160-1" }, { "uniprot_canonical_ac": "P34161-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 385, "chemical_mass": 42739.0, "gene_names": "YOX1;YOX1", "protein_name": "Homeobox protein YOX1", "disease": [ { "disease_id": "DOID:11836", "name": "clubfoot", "description": "A bone development disease where one or both are inclined inwards, axially rotated outwards, and pointing downwards with concomitant soft tissue abnormalities.", "url": "https://disease-ontology.org/term/DOID:11836", "evidence": [ { "id": "11836", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11836" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P34161", "url": "https://www.uniprot.org/uniprotkb/P34161" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34161-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Thr132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Ser252", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Thr289", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Ser302", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Thr303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Ser305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Thr322", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Thr324", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Thr328", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Ser329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Ser346", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Ser358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34161-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004489", "url": "https://www.yeastgenome.org/locus/S000004489" }, { "database": "iPTMnet", "id": "P34161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P34161-1" }, { "uniprot_canonical_ac": "P34162-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 210, "chemical_mass": 22894.0, "gene_names": "SRB2;HRS2;MED20;SRB2", "protein_name": "Mediator of RNA polymerase II transcription subunit 20", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" }, { "name": "cellular response to nutrient levels", "id": "GO:0031669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031669", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" }, { "name": "negative regulation of ribosomal protein gene transcription by RNA polymerase II", "id": "GO:0010688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010688", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" }, { "name": "TFIID-class transcription factor complex binding", "id": "GO:0001094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001094", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34162-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Pro14", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "H", "comment": "In SRB2-1; suppresses the phenotypic defects of an RNA polymerase IICTD truncation.", "evidence": [ { "database": "UniProtKB", "id": "P34162", "url": "https://www.uniprot.org/uniprotkb/P34162" }, { "database": "PubMed", "id": "1591782", "url": "https://glygen.org/publication/PubMed/1591782" } ] } ] } ], "record_id": "P34162-1" }, { "uniprot_canonical_ac": "P34163-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 548, "chemical_mass": 62979.0, "gene_names": "TGL1;TGL1;YKL5", "protein_name": "Sterol esterase TGL1", "disease": [ { "disease_id": "DOID:0060717", "name": "autosomal recessive congenital ichthyosis 8", "description": "An autosomal recessive congenital ichthyosis characterized by diffuse lamellar ichthyosis, slight facial erythema, hyperkeratosis, orthokeratosis, hypergranulosis, and acanthosis that has_material_basis_in homozygous mutation in the LIPN gene on chromosome 10q23.", "url": "https://disease-ontology.org/term/DOID:0060717", "evidence": [ { "id": "0060717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060717" } ], "weight": 0.0 }, { "disease_id": "DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31.", "url": "https://disease-ontology.org/term/DOID:0080217", "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ], "weight": 0.0 }, { "disease_id": "DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.", "url": "https://disease-ontology.org/term/DOID:14497", "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ], "weight": 0.0 }, { "disease_id": "DOID:14502", "name": "cholesterol ester storage disease", "description": "A lysosomal acid lipase deficiency characterized by onset in childhood or later of progressive accumulation of cholesteryl esters and triglycerides primarily in the liver and spleen.", "url": "https://disease-ontology.org/term/DOID:14502", "evidence": [ { "id": "14502", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14502" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "sterol ester esterase activity", "id": "GO:0004771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004771", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" } ], "pmid": "" } ], "cellular_component": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" } ], "pmid": "" }, { "name": "sterol metabolic process", "id": "GO:0016125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016125", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34163-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Tyr253", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "437", "end_pos": "437", "site_lbl": "Ser437", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Thr460", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "462", "end_pos": "462", "site_lbl": "Ser462", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Ser466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Ser469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Ser492", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Ser494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "508", "end_pos": "508", "site_lbl": "Thr508", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "521", "end_pos": "521", "site_lbl": "Ser521", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Ser526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "537", "end_pos": "537", "site_lbl": "Ser537", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Ser538", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Thr539", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34163", "url": "https://www.uniprot.org/uniprotkb/P34163" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34163-1", "start_pos": "540", "end_pos": "540", "site_lbl": "Thr540", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001623", "url": "https://www.yeastgenome.org/locus/S000001623" }, { "database": "iPTMnet", "id": "P34163", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34163" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P34163-1" }, { "uniprot_canonical_ac": "P34167-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 436, "chemical_mass": 48522.0, "gene_names": "TIF3;P9325.6;RBL3;STM1;TIF3;TIF42", "protein_name": "Eukaryotic translation initiation factor 4B", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:1470", "name": "major depressive disorder", "description": "A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.", "url": "https://disease-ontology.org/term/DOID:1470", "evidence": [ { "id": "1470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1470" } ], "weight": 0.0 }, { "disease_id": "DOID:1928", "name": "Williams-Beuren syndrome", "description": "A syndrome that is characterized by mild to moderate intellectual disability, a broad forehead, a short nose with a broad tip, full cheeks, and a wide mouth with full lips and difficulty with visual-spatial tasks and has_material_basis_in hemizygous deletion of 1.5 to 1.8 Mb on chromosome 7q11.23.", "url": "https://disease-ontology.org/term/DOID:1928", "evidence": [ { "id": "1928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1928" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "ribosomal small subunit binding", "id": "GO:0043024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043024", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "RNA strand-exchange activity", "id": "GO:0034057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034057", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "RNA strand annealing activity", "id": "GO:0033592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033592", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" } ], "biological_process": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 4F complex assembly", "id": "GO:0097010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097010", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34167-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Ser199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Ser300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Ser364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "366", "end_pos": "366", "site_lbl": "Thr366", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Thr370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Thr371", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "380", "end_pos": "380", "site_lbl": "Ser380", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Thr387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Ser86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "32027465", "url": "https://glygen.org/publication/PubMed/32027465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000006367", "url": "https://www.yeastgenome.org/locus/S000006367" }, { "database": "iPTMnet", "id": "P34167", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34167" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Asn106", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "G", "comment": "Retention of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] }, { "sequence_org": "N", "sequence_mut": "P", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] }, { "sequence_org": "N", "sequence_mut": "S", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] }, { "sequence_org": "N", "sequence_mut": "V", "comment": "Retention of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] }, { "sequence_org": "N", "sequence_mut": "Y", "comment": "Retention of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] } ] }, { "uniprot_canonical_ac": "P34167-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Ala150", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "C", "comment": "Retention of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] }, { "sequence_org": "A", "sequence_mut": "F", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] }, { "sequence_org": "A", "sequence_mut": "L", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] }, { "sequence_org": "A", "sequence_mut": "N", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] }, { "sequence_org": "A", "sequence_mut": "S", "comment": "Retention of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] }, { "sequence_org": "A", "sequence_mut": "Y", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P34167", "url": "https://www.uniprot.org/uniprotkb/P34167" }, { "database": "PubMed", "id": "8404866", "url": "https://glygen.org/publication/PubMed/8404866" } ] } ] } ], "record_id": "P34167-1" }, { "uniprot_canonical_ac": "P34218-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 831, "chemical_mass": 97582.0, "gene_names": "SAS3;KAT6;SAS3;YBL0507;YBL0515", "protein_name": "Histone acetyltransferase SAS3", "disease": [ { "disease_id": "DOID:0060290", "name": "Ohdo syndrome, SBBYS variant", "description": "A Ohdo syndrome that is characterized by blepharophimosis, ptosis and intellectual disability and that has_material_basis_in heterozygous mutation in the KAT6B gene on chromosome 10q22.", "url": "https://disease-ontology.org/term/DOID:0060290", "evidence": [ { "id": "0060290", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060290" } ], "weight": 0.0 }, { "disease_id": "DOID:11198", "name": "DiGeorge syndrome", "description": "A syndrome that has_material_basis_in a large deletion of the chromosome 22q11.2 region which includes the DGS gene needed for development of the thymus and related glands with subsequent lack of T-cell production.", "url": "https://disease-ontology.org/term/DOID:11198", "evidence": [ { "id": "11198", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11198" } ], "weight": 0.0 }, { "disease_id": "DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells.", "url": "https://disease-ontology.org/term/DOID:127", "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:3490", "name": "Noonan syndrome", "description": "A RASopathy that is characterized by mildly unusual facial features, short stature, heart defects, bleeding problems, skeletal malformations, and many other signs and symptoms.", "url": "https://disease-ontology.org/term/DOID:3490", "evidence": [ { "id": "3490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3490" } ], "weight": 0.0 }, { "disease_id": "DOID:4674", "name": "androgen insensitivity syndrome", "description": "A disorder of sexual development that is characterized by the inability of the cell to respond to androgens in individuals with a karyotype of 46,XY resulting in female physical traits but male genetic makeup.", "url": "https://disease-ontology.org/term/DOID:4674", "evidence": [ { "id": "4674", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4674" } ], "weight": 0.0 } ], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "histone acetyltransferase activity", "id": "GO:0004402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "NuA3a histone acetyltransferase complex", "id": "GO:1990467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990467", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "NuA3b histone acetyltransferase complex", "id": "GO:1990468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990468", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" }, { "name": "NuA3 histone acetyltransferase complex", "id": "GO:0033100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033100", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34218-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Thr246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000148", "url": "https://www.yeastgenome.org/locus/S000000148" }, { "database": "iPTMnet", "id": "P34218", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34218" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34218-1", "start_pos": "532", "end_pos": "532", "site_lbl": "Ser532", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000148", "url": "https://www.yeastgenome.org/locus/S000000148" }, { "database": "iPTMnet", "id": "P34218", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34218" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34218-1", "start_pos": "533", "end_pos": "533", "site_lbl": "Ser533", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000148", "url": "https://www.yeastgenome.org/locus/S000000148" }, { "database": "iPTMnet", "id": "P34218", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34218" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34218-1", "start_pos": "718", "end_pos": "718", "site_lbl": "Thr718", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000148", "url": "https://www.yeastgenome.org/locus/S000000148" }, { "database": "iPTMnet", "id": "P34218", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34218" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34218-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000148", "url": "https://www.yeastgenome.org/locus/S000000148" }, { "database": "iPTMnet", "id": "P34218", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34218" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34218-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Cys303", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Greatly diminishes HAT activity.", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" }, { "database": "PubMed", "id": "10600516", "url": "https://glygen.org/publication/PubMed/10600516" }, { "database": "PubMed", "id": "10817755", "url": "https://glygen.org/publication/PubMed/10817755" } ] } ] }, { "uniprot_canonical_ac": "P34218-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Cys306", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Greatly diminishes HAT activity.", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" }, { "database": "PubMed", "id": "10600516", "url": "https://glygen.org/publication/PubMed/10600516" }, { "database": "PubMed", "id": "10817755", "url": "https://glygen.org/publication/PubMed/10817755" } ] } ] }, { "uniprot_canonical_ac": "P34218-1", "start_pos": "319", "end_pos": "319", "site_lbl": "His319", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Greatly diminishes HAT activity.", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" }, { "database": "PubMed", "id": "10600516", "url": "https://glygen.org/publication/PubMed/10600516" }, { "database": "PubMed", "id": "10817755", "url": "https://glygen.org/publication/PubMed/10817755" } ] } ] }, { "uniprot_canonical_ac": "P34218-1", "start_pos": "323", "end_pos": "323", "site_lbl": "Cys323", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Abolishes HAT activity.", "evidence": [ { "database": "UniProtKB", "id": "P34218", "url": "https://www.uniprot.org/uniprotkb/P34218" }, { "database": "PubMed", "id": "10817755", "url": "https://glygen.org/publication/PubMed/10817755" }, { "database": "PubMed", "id": "10600516", "url": "https://glygen.org/publication/PubMed/10600516" } ] } ] } ], "record_id": "P34218-1" }, { "uniprot_canonical_ac": "P34219-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 525, "chemical_mass": 59226.0, "gene_names": "TOD6;PBF1;TOD6;YBL0509;YBL0513", "protein_name": "Transcriptional regulatory protein TOD6", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" } ], "pmid": "" }, { "name": "Rpd3L-Expanded complex", "id": "GO:0070210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070210", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34219-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Thr147", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 147, "start_aa": "Thr", "end_pos": 147, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr147", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Thr152", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 152, "start_aa": "Thr", "end_pos": 152, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr152", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Tyr141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Ser228", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Ser276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Ser280", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Ser300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Ser303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Ser304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Ser308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Ser317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Ser318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Ser321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Thr325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Ser329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "333", "end_pos": "333", "site_lbl": "Ser333", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Ser337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Tyr339", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Ser341", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "366", "end_pos": "366", "site_lbl": "Ser366", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34219", "url": "https://www.uniprot.org/uniprotkb/P34219" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Thr383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Thr475", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "480", "end_pos": "480", "site_lbl": "Ser480", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Tyr483", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "500", "end_pos": "500", "site_lbl": "Ser500", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Ser503", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34219-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000150", "url": "https://www.yeastgenome.org/locus/S000000150" }, { "database": "iPTMnet", "id": "P34219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34219" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P34219-1" }, { "uniprot_canonical_ac": "P34221-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 468, "chemical_mass": 51332.0, "gene_names": "PTC3;PTC3;YBL0511;YBL0513", "protein_name": "Protein phosphatase 2C homolog 3", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" } ], "pmid": "" }, { "name": "regulation of cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0000079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000079", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" } ], "pmid": "" }, { "name": "negative regulation of p38MAPK cascade", "id": "GO:1903753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903753", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" } ], "pmid": "" }, { "name": "regulation of mitotic DNA damage checkpoint", "id": "GO:1904289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904289", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34221-1", "start_pos": "373", "end_pos": "373", "site_lbl": "Thr373", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 373, "start_aa": "Thr", "end_pos": 373, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr373", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000152", "url": "https://www.yeastgenome.org/locus/S000000152" }, { "database": "iPTMnet", "id": "P34221", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34221" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34221-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Ser324", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34221", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34221" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000152", "url": "https://www.yeastgenome.org/locus/S000000152" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34221-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Ser332", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34221", "url": "https://www.uniprot.org/uniprotkb/P34221" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P34221", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34221" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000152", "url": "https://www.yeastgenome.org/locus/S000000152" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34221-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000152", "url": "https://www.yeastgenome.org/locus/S000000152" }, { "database": "iPTMnet", "id": "P34221", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34221" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34221-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000152", "url": "https://www.yeastgenome.org/locus/S000000152" }, { "database": "iPTMnet", "id": "P34221", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34221" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34221-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Ser375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000152", "url": "https://www.yeastgenome.org/locus/S000000152" }, { "database": "iPTMnet", "id": "P34221", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34221" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34221-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34221", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34221" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000152", "url": "https://www.yeastgenome.org/locus/S000000152" } ] } ] } ], "record_id": "P34221-1" }, { "uniprot_canonical_ac": "P34222-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34222", "url": "https://www.uniprot.org/uniprotkb/P34222" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 208, "chemical_mass": 22435.0, "gene_names": "PTH2;PTH2;YBL0510;YBL0514", "protein_name": "Peptidyl-tRNA hydrolase 2", "disease": [], "molecular_function": [ { "name": "peptidyl-tRNA hydrolase activity", "id": "GO:0004045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004045", "evidence": [ { "database": "UniProtKB", "id": "P34222", "url": "https://www.uniprot.org/uniprotkb/P34222" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P34222", "url": "https://www.uniprot.org/uniprotkb/P34222" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P34222", "url": "https://www.uniprot.org/uniprotkb/P34222" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P34222", "url": "https://www.uniprot.org/uniprotkb/P34222" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "P34222", "url": "https://www.uniprot.org/uniprotkb/P34222" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34222-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000153", "url": "https://www.yeastgenome.org/locus/S000000153" }, { "database": "iPTMnet", "id": "P34222", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34222" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34222-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000153", "url": "https://www.yeastgenome.org/locus/S000000153" }, { "database": "iPTMnet", "id": "P34222", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34222" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P34222-1" }, { "uniprot_canonical_ac": "P34225-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 687, "chemical_mass": 78768.0, "gene_names": "YEL1;YBL0507;YBL0517;YEL1", "protein_name": "Guanine-nucleotide exchange factor YEL1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of phosphatidylinositol biosynthetic process", "id": "GO:0010513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010513", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" } ], "pmid": "" }, { "name": "actin cortical patch localization", "id": "GO:0051666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051666", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" } ], "pmid": "" }, { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34225-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Thr270", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Ser272", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Thr274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Ser275", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Ser279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Ser283", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Ser289", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Thr290", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Ser293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Ser297", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Thr298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Ser299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34225", "url": "https://www.uniprot.org/uniprotkb/P34225" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Ser303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Ser308", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Thr310", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Ser319", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Thr40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Thr412", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Ser417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Ser498", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34225-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Thr50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000156", "url": "https://www.yeastgenome.org/locus/S000000156" }, { "database": "iPTMnet", "id": "P34225", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34225" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P34225-1" }, { "uniprot_canonical_ac": "P34226-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 696, "chemical_mass": 77066.0, "gene_names": "SKT5;CAL2;CHS4;CSD4;SKT5;YBL0506;YBL0519", "protein_name": "Chitin synthase regulator SKT5", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" } ], "pmid": "" } ], "biological_process": [ { "name": "chitin biosynthetic process", "id": "GO:0006031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006031", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34226-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Thr131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Thr135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Thr138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Ser152", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Tyr155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Thr163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Thr166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "543", "end_pos": "543", "site_lbl": "Ser543", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "550", "end_pos": "550", "site_lbl": "Ser550", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "561", "end_pos": "561", "site_lbl": "Ser561", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "563", "end_pos": "563", "site_lbl": "Ser563", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Thr564", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Thr570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "573", "end_pos": "573", "site_lbl": "Ser573", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Thr575", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "576", "end_pos": "576", "site_lbl": "Ser576", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Thr57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Ser585", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Ser586", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "588", "end_pos": "588", "site_lbl": "Ser588", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "590", "end_pos": "590", "site_lbl": "Thr590", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "622", "end_pos": "622", "site_lbl": "Ser622", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "624", "end_pos": "624", "site_lbl": "Thr624", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "625", "end_pos": "625", "site_lbl": "Ser625", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "630", "end_pos": "630", "site_lbl": "Ser630", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "644", "end_pos": "644", "site_lbl": "Ser644", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Ser652", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "658", "end_pos": "658", "site_lbl": "Ser658", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "29763674", "url": "https://glygen.org/publication/PubMed/29763674" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "671", "end_pos": "671", "site_lbl": "Thr671", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "673", "end_pos": "673", "site_lbl": "Ser673", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "677", "end_pos": "677", "site_lbl": "Thr677", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "678", "end_pos": "678", "site_lbl": "Ser678", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000157", "url": "https://www.yeastgenome.org/locus/S000000157" }, { "database": "iPTMnet", "id": "P34226", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34226" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34226-1", "start_pos": "693", "end_pos": "693", "site_lbl": "Cys693", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes SKT5 prenylation. Decreases chitin synthase CHS3 activity. Decreases chitin chain length. Decreases cellular chitin level. Normal SKT5 localization to cellular membranes. Resistance to Calcofluor White (cell wall stressor).", "evidence": [ { "database": "UniProtKB", "id": "P34226", "url": "https://www.uniprot.org/uniprotkb/P34226" }, { "database": "PubMed", "id": "17142567", "url": "https://glygen.org/publication/PubMed/17142567" } ] } ] } ], "record_id": "P34226-1" }, { "uniprot_canonical_ac": "P34227-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34227", "url": "https://www.uniprot.org/uniprotkb/P34227" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 261, "chemical_mass": 29496.0, "gene_names": "PRX1;PRX1;YBL0503;YBL0524", "protein_name": "Peroxiredoxin PRX1, mitochondrial", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P34227", "url": "https://www.uniprot.org/uniprotkb/P34227" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P34227", "url": "https://www.uniprot.org/uniprotkb/P34227" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P34227", "url": "https://www.uniprot.org/uniprotkb/P34227" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "P34227", "url": "https://www.uniprot.org/uniprotkb/P34227" } ], "pmid": "" } ], "molecular_function": [ { "name": "thioredoxin peroxidase activity", "id": "GO:0008379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008379", "evidence": [ { "database": "UniProtKB", "id": "P34227", "url": "https://www.uniprot.org/uniprotkb/P34227" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34227-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Ser170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000160", "url": "https://www.yeastgenome.org/locus/S000000160" }, { "database": "iPTMnet", "id": "P34227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34227" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34227-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Thr173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34227" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34227-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34227" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34227-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000160", "url": "https://www.yeastgenome.org/locus/S000000160" }, { "database": "iPTMnet", "id": "P34227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34227" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34227-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000160", "url": "https://www.yeastgenome.org/locus/S000000160" }, { "database": "iPTMnet", "id": "P34227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34227" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34227-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34227", "url": "https://www.uniprot.org/uniprotkb/P34227" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P34227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34227" }, { "database": "SGD", "id": "S000000160", "url": "https://www.yeastgenome.org/locus/S000000160" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34227-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Cys38", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Impairs dimer formation.", "evidence": [ { "database": "UniProtKB", "id": "P34227", "url": "https://www.uniprot.org/uniprotkb/P34227" }, { "database": "PubMed", "id": "10821871", "url": "https://glygen.org/publication/PubMed/10821871" } ] } ] }, { "uniprot_canonical_ac": "P34227-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Cys91", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No activity.", "evidence": [ { "database": "UniProtKB", "id": "P34227", "url": "https://www.uniprot.org/uniprotkb/P34227" }, { "database": "PubMed", "id": "10681558", "url": "https://glygen.org/publication/PubMed/10681558" } ] } ] } ], "record_id": "P34227-1" }, { "uniprot_canonical_ac": "P34233-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 588, "chemical_mass": 65685.0, "gene_names": "ASH1;ASH1", "protein_name": "Transcriptional regulatory protein ASH1", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" }, { "name": "positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter", "id": "GO:1900461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900461", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" }, { "name": "negative regulation of mating type switching", "id": "GO:0031495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031495", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" }, { "name": "Rpd3L-Expanded complex", "id": "GO:0070210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070210", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" }, { "name": "Rpd3L complex", "id": "GO:0033698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033698", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34233-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Thr290", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 290, "start_aa": "Thr", "end_pos": 290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr290", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "21098119", "url": "https://glygen.org/publication/PubMed/21098119" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Ser253", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Thr286", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "21098119", "url": "https://glygen.org/publication/PubMed/21098119" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Ser294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "21098119", "url": "https://glygen.org/publication/PubMed/21098119" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Ser360", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Ser397", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "415", "end_pos": "415", "site_lbl": "Ser415", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Ser424", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "27807972", "url": "https://glygen.org/publication/PubMed/27807972" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Ser426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "27807972", "url": "https://glygen.org/publication/PubMed/27807972" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Thr429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "27807972", "url": "https://glygen.org/publication/PubMed/27807972" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Thr431", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "440", "end_pos": "440", "site_lbl": "Ser440", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Ser441", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "442", "end_pos": "442", "site_lbl": "Ser442", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "27807972", "url": "https://glygen.org/publication/PubMed/27807972" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "449", "end_pos": "449", "site_lbl": "Tyr449", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Thr450", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27807972", "url": "https://glygen.org/publication/PubMed/27807972" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27807972", "url": "https://glygen.org/publication/PubMed/27807972" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Ser455", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27807972", "url": "https://glygen.org/publication/PubMed/27807972" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Tyr458", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "465", "end_pos": "465", "site_lbl": "Ser465", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27807972", "url": "https://glygen.org/publication/PubMed/27807972" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Ser469", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "27807972", "url": "https://glygen.org/publication/PubMed/27807972" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "474", "end_pos": "474", "site_lbl": "Ser474", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "476", "end_pos": "476", "site_lbl": "Ser476", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Ser477", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "27807972", "url": "https://glygen.org/publication/PubMed/27807972" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "513", "end_pos": "513", "site_lbl": "Ser513", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Ser54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34233", "url": "https://www.uniprot.org/uniprotkb/P34233" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Thr87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34233-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Tyr97", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001668", "url": "https://www.yeastgenome.org/locus/S000001668" }, { "database": "iPTMnet", "id": "P34233", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34233" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P34233-1" }, { "uniprot_canonical_ac": "P34244-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1518, "chemical_mass": 169607.0, "gene_names": "HSL1;ELM2;HSL1;NIK1;YKL453", "protein_name": "Probable serine/threonine-protein kinase HSL1", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "cellular bud neck septin ring", "id": "GO:0000144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000144", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" } ], "biological_process": [ { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "mitotic morphogenesis checkpoint signaling", "id": "GO:0044879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044879", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "protein localization to septin ring", "id": "GO:1902935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902935", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" }, { "name": "negative regulation of diacylglycerol biosynthetic process", "id": "GO:1900481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900481", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34244-1", "start_pos": "1010", "end_pos": "1010", "site_lbl": "Ser1010", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1016", "end_pos": "1016", "site_lbl": "Ser1016", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1018", "end_pos": "1018", "site_lbl": "Ser1018", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1022", "end_pos": "1022", "site_lbl": "Ser1022", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1033", "end_pos": "1033", "site_lbl": "Ser1033", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1035", "end_pos": "1035", "site_lbl": "Thr1035", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1038", "end_pos": "1038", "site_lbl": "Ser1038", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1045", "end_pos": "1045", "site_lbl": "Ser1045", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1052", "end_pos": "1052", "site_lbl": "Ser1052", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1098", "end_pos": "1098", "site_lbl": "Ser1098", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1103", "end_pos": "1103", "site_lbl": "Ser1103", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1125", "end_pos": "1125", "site_lbl": "Ser1125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1176", "end_pos": "1176", "site_lbl": "Ser1176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1195", "end_pos": "1195", "site_lbl": "Ser1195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1197", "end_pos": "1197", "site_lbl": "Tyr1197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1203", "end_pos": "1203", "site_lbl": "Ser1203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1210", "end_pos": "1210", "site_lbl": "Thr1210", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1215", "end_pos": "1215", "site_lbl": "Ser1215", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1220", "end_pos": "1220", "site_lbl": "Ser1220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "IntAct", "id": "P34244", "url": "https://www.ebi.ac.uk/intact/interactors/id:P34244*" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "16688223", "url": "https://glygen.org/publication/PubMed/16688223" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1234", "end_pos": "1234", "site_lbl": "Ser1234", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1239", "end_pos": "1239", "site_lbl": "Ser1239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1242", "end_pos": "1242", "site_lbl": "Ser1242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1248", "end_pos": "1248", "site_lbl": "Ser1248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1250", "end_pos": "1250", "site_lbl": "Ser1250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1253", "end_pos": "1253", "site_lbl": "Ser1253", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1267", "end_pos": "1267", "site_lbl": "Ser1267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1277", "end_pos": "1277", "site_lbl": "Ser1277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1279", "end_pos": "1279", "site_lbl": "Ser1279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1284", "end_pos": "1284", "site_lbl": "Ser1284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1287", "end_pos": "1287", "site_lbl": "Ser1287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1325", "end_pos": "1325", "site_lbl": "Ser1325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1328", "end_pos": "1328", "site_lbl": "Ser1328", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1329", "end_pos": "1329", "site_lbl": "Ser1329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "1368", "end_pos": "1368", "site_lbl": "Ser1368", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Ser154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Thr156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Thr273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "18768748", "url": "https://glygen.org/publication/PubMed/18768748" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19211841", "url": "https://glygen.org/publication/PubMed/19211841" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Ser394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Ser405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "21725298", "url": "https://glygen.org/publication/PubMed/21725298" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Thr410", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Ser470", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "476", "end_pos": "476", "site_lbl": "Ser476", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "480", "end_pos": "480", "site_lbl": "Ser480", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Ser481", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "501", "end_pos": "501", "site_lbl": "Ser501", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "508", "end_pos": "508", "site_lbl": "Thr508", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "511", "end_pos": "511", "site_lbl": "Ser511", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "516", "end_pos": "516", "site_lbl": "Ser516", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Thr53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "547", "end_pos": "547", "site_lbl": "Ser547", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "550", "end_pos": "550", "site_lbl": "Thr550", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "552", "end_pos": "552", "site_lbl": "Ser552", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "556", "end_pos": "556", "site_lbl": "Ser556", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "576", "end_pos": "576", "site_lbl": "Ser576", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Ser577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "584", "end_pos": "584", "site_lbl": "Ser584", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Tyr585", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Thr586", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "587", "end_pos": "587", "site_lbl": "Ser587", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "589", "end_pos": "589", "site_lbl": "Ser589", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "590", "end_pos": "590", "site_lbl": "Ser590", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Ser599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Ser601", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Ser604", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "606", "end_pos": "606", "site_lbl": "Ser606", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "608", "end_pos": "608", "site_lbl": "Ser608", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Ser610", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Thr613", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "627", "end_pos": "627", "site_lbl": "Ser627", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "629", "end_pos": "629", "site_lbl": "Ser629", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Thr62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "631", "end_pos": "631", "site_lbl": "Tyr631", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Ser632", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "634", "end_pos": "634", "site_lbl": "Ser634", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "641", "end_pos": "641", "site_lbl": "Ser641", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "643", "end_pos": "643", "site_lbl": "Ser643", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "644", "end_pos": "644", "site_lbl": "Thr644", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "671", "end_pos": "671", "site_lbl": "Ser671", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "674", "end_pos": "674", "site_lbl": "Ser674", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "676", "end_pos": "676", "site_lbl": "Tyr676", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "677", "end_pos": "677", "site_lbl": "Ser677", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "680", "end_pos": "680", "site_lbl": "Ser680", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "682", "end_pos": "682", "site_lbl": "Ser682", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "685", "end_pos": "685", "site_lbl": "Ser685", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "767", "end_pos": "767", "site_lbl": "Thr767", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "772", "end_pos": "772", "site_lbl": "Ser772", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "802", "end_pos": "802", "site_lbl": "Ser802", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "805", "end_pos": "805", "site_lbl": "Ser805", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "815", "end_pos": "815", "site_lbl": "Thr815", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "817", "end_pos": "817", "site_lbl": "Ser817", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "818", "end_pos": "818", "site_lbl": "Ser818", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "819", "end_pos": "819", "site_lbl": "Ser819", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "820", "end_pos": "820", "site_lbl": "Tyr820", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "832", "end_pos": "832", "site_lbl": "Ser832", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "835", "end_pos": "835", "site_lbl": "Thr835", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "837", "end_pos": "837", "site_lbl": "Ser837", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "866", "end_pos": "866", "site_lbl": "Ser866", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34244", "url": "https://www.uniprot.org/uniprotkb/P34244" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "880", "end_pos": "880", "site_lbl": "Ser880", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "899", "end_pos": "899", "site_lbl": "Ser899", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "908", "end_pos": "908", "site_lbl": "Ser908", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "948", "end_pos": "948", "site_lbl": "Ser948", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "963", "end_pos": "963", "site_lbl": "Ser963", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34244-1", "start_pos": "997", "end_pos": "997", "site_lbl": "Ser997", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34244" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "SGD", "id": "S000001584", "url": "https://www.yeastgenome.org/locus/S000001584" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P34244-1" }, { "uniprot_canonical_ac": "P34247-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 250, "chemical_mass": 29735.0, "gene_names": "UTP11;UTP11;YKL449", "protein_name": "U3 small nucleolar RNA-associated protein 11", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "pmid": "" }, { "name": "sno(s)RNA-containing ribonucleoprotein complex", "id": "GO:0005732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005732", "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "pmid": "" } ], "biological_process": [ { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "P34247", "url": "https://www.uniprot.org/uniprotkb/P34247" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34247-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Thr147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001582", "url": "https://www.yeastgenome.org/locus/S000001582" }, { "database": "iPTMnet", "id": "P34247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34247" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34247-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001582", "url": "https://www.yeastgenome.org/locus/S000001582" }, { "database": "iPTMnet", "id": "P34247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34247" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P34247-1" }, { "uniprot_canonical_ac": "P34252-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 453, "chemical_mass": 52272.0, "gene_names": "SLD2;DRC1;SLD2;YKL463", "protein_name": "DNA replication regulator SLD2", "disease": [], "molecular_function": [ { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" } ], "cellular_component": [ { "name": "DNA replication preinitiation complex", "id": "GO:0031261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031261", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA replication preinitiation complex assembly", "id": "GO:0071163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071163", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" }, { "name": "mitotic DNA replication preinitiation complex assembly", "id": "GO:1902977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902977", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" }, { "name": "negative regulation of protein-containing complex assembly", "id": "GO:0031333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031333", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" }, { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" }, { "name": "regulation of mitotic DNA replication initiation", "id": "GO:1903466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903466", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34252-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Thr84", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 84, "start_aa": "Thr", "end_pos": 84, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr84", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "16619031", "url": "https://glygen.org/publication/PubMed/16619031" }, { "database": "PubMed", "id": "17167417", "url": "https://glygen.org/publication/PubMed/17167417" } ] }, { "kinase_uniprot_canonical_ac": "P30283-1", "kinase_gene_name": "CLB5", "evidence": [ { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "16619031", "url": "https://glygen.org/publication/PubMed/16619031" }, { "database": "PubMed", "id": "17167417", "url": "https://glygen.org/publication/PubMed/17167417" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "16619031", "url": "https://glygen.org/publication/PubMed/16619031" }, { "database": "PubMed", "id": "20485558", "url": "https://glygen.org/publication/PubMed/20485558" }, { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34088668", "url": "https://glygen.org/publication/PubMed/34088668" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "No interaction with DPB11.", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" }, { "database": "PubMed", "id": "16619031", "url": "https://glygen.org/publication/PubMed/16619031" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Ser100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "11807498", "url": "https://glygen.org/publication/PubMed/11807498" }, { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "PubMed", "id": "34088668", "url": "https://glygen.org/publication/PubMed/34088668" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No interaction with DPB11.", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" }, { "database": "PubMed", "id": "16619031", "url": "https://glygen.org/publication/PubMed/16619031" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Ser128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "11807498", "url": "https://glygen.org/publication/PubMed/11807498" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Ser150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Thr168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "11807498", "url": "https://glygen.org/publication/PubMed/11807498" }, { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "11807498", "url": "https://glygen.org/publication/PubMed/11807498" }, { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34088668", "url": "https://glygen.org/publication/PubMed/34088668" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Ser208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "11807498", "url": "https://glygen.org/publication/PubMed/11807498" }, { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Normal interaction with DPB11.", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" }, { "database": "PubMed", "id": "16619031", "url": "https://glygen.org/publication/PubMed/16619031" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Thr241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "11807498", "url": "https://glygen.org/publication/PubMed/11807498" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Reduced interaction with DPB11.", "evidence": [ { "database": "UniProtKB", "id": "P34252", "url": "https://www.uniprot.org/uniprotkb/P34252" }, { "database": "PubMed", "id": "16619031", "url": "https://glygen.org/publication/PubMed/16619031" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Ser254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Thr29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34252-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Tyr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001591", "url": "https://www.yeastgenome.org/locus/S000001591" }, { "database": "iPTMnet", "id": "P34252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P34252-1" }, { "uniprot_canonical_ac": "P34756-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 2278, "chemical_mass": 257420.0, "gene_names": "FAB1;FAB1;SVL7", "protein_name": "1-phosphatidylinositol 3-phosphate 5-kinase FAB1", "disease": [ { "disease_id": "DOID:0060448", "name": "Fleck corneal dystrophy", "description": "A stromal dystrophy that is characterized by numerous tiny, dot-like white flecks scattered in all layers of the corneal stroma and that has_material_basis_in heterozygous mutation in the PIKFYVE gene on chromosome 2q34.", "url": "https://disease-ontology.org/term/DOID:0060448", "evidence": [ { "id": "0060448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060448" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-3-phosphate 5-kinase activity", "id": "GO:0000285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000285", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" }, { "name": "PAS complex", "id": "GO:0070772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070772", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" } ], "biological_process": [ { "name": "vacuole organization", "id": "GO:0007033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007033", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" }, { "name": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process", "id": "GO:1903100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903100", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" }, { "name": "regulation of phosphatidylinositol biosynthetic process", "id": "GO:0010511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010511", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34756-1", "start_pos": "1733", "end_pos": "1733", "site_lbl": "Ser1733", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1733, "start_aa": "Ser", "end_pos": 1733, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1733", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1800", "end_pos": "1800", "site_lbl": "Ser1800", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1800, "start_aa": "Ser", "end_pos": 1800, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1800", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1808", "end_pos": "1808", "site_lbl": "Thr1808", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1808, "start_aa": "Thr", "end_pos": 1808, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1808", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1809", "end_pos": "1809", "site_lbl": "Thr1809", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1809, "start_aa": "Thr", "end_pos": 1809, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1809", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1810", "end_pos": "1810", "site_lbl": "Thr1810", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1810, "start_aa": "Thr", "end_pos": 1810, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1810", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1817", "end_pos": "1817", "site_lbl": "Ser1817", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1817, "start_aa": "Ser", "end_pos": 1817, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1817", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Thr526", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 526, "start_aa": "Thr", "end_pos": 526, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr526", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "690", "end_pos": "690", "site_lbl": "Ser690", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 690, "start_aa": "Ser", "end_pos": 690, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser690", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "697", "end_pos": "697", "site_lbl": "Ser697", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 697, "start_aa": "Ser", "end_pos": 697, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser697", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 75, "start_aa": "Ser", "end_pos": 75, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser75", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Thr78", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 78, "start_aa": "Thr", "end_pos": 78, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr78", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 79, "start_aa": "Ser", "end_pos": 79, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser79", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 80, "start_aa": "Ser", "end_pos": 80, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser80", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Ser81", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 81, "start_aa": "Ser", "end_pos": 81, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser81", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 87, "start_aa": "Ser", "end_pos": 87, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser87", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Ser89", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 89, "start_aa": "Ser", "end_pos": 89, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser89", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 96, "start_aa": "Ser", "end_pos": 96, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser96", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 98, "start_aa": "Ser", "end_pos": 98, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser98", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34756", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34756" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1049", "end_pos": "1049", "site_lbl": "Ser1049", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1064", "end_pos": "1064", "site_lbl": "Tyr1064", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1127", "end_pos": "1127", "site_lbl": "Ser1127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33157024", "url": "https://glygen.org/publication/PubMed/33157024" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Ser140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1512", "end_pos": "1512", "site_lbl": "Ser1512", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33157024", "url": "https://glygen.org/publication/PubMed/33157024" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1569", "end_pos": "1569", "site_lbl": "Thr1569", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "28637746", "url": "https://glygen.org/publication/PubMed/28637746" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1583", "end_pos": "1583", "site_lbl": "Thr1583", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "28637746", "url": "https://glygen.org/publication/PubMed/28637746" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1594", "end_pos": "1594", "site_lbl": "Thr1594", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "28637746", "url": "https://glygen.org/publication/PubMed/28637746" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1606", "end_pos": "1606", "site_lbl": "Ser1606", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1608", "end_pos": "1608", "site_lbl": "Thr1608", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1611", "end_pos": "1611", "site_lbl": "Ser1611", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1626", "end_pos": "1626", "site_lbl": "Ser1626", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1627", "end_pos": "1627", "site_lbl": "Ser1627", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1630", "end_pos": "1630", "site_lbl": "Ser1630", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1691", "end_pos": "1691", "site_lbl": "Thr1691", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "28637746", "url": "https://glygen.org/publication/PubMed/28637746" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1712", "end_pos": "1712", "site_lbl": "Ser1712", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1713", "end_pos": "1713", "site_lbl": "Ser1713", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1718", "end_pos": "1718", "site_lbl": "Ser1718", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1831", "end_pos": "1831", "site_lbl": "Ser1831", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Thr183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1924", "end_pos": "1924", "site_lbl": "Ser1924", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "28637746", "url": "https://glygen.org/publication/PubMed/28637746" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1931", "end_pos": "1931", "site_lbl": "Ser1931", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1938", "end_pos": "1938", "site_lbl": "Ser1938", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1941", "end_pos": "1941", "site_lbl": "Ser1941", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1942", "end_pos": "1942", "site_lbl": "Ser1942", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1945", "end_pos": "1945", "site_lbl": "Thr1945", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1946", "end_pos": "1946", "site_lbl": "Thr1946", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1953", "end_pos": "1953", "site_lbl": "Thr1953", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "28637746", "url": "https://glygen.org/publication/PubMed/28637746" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1963", "end_pos": "1963", "site_lbl": "Thr1963", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "28637746", "url": "https://glygen.org/publication/PubMed/28637746" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1971", "end_pos": "1971", "site_lbl": "Ser1971", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33157024", "url": "https://glygen.org/publication/PubMed/33157024" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Thr206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Ser208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33157024", "url": "https://glygen.org/publication/PubMed/33157024" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Ser210", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33157024", "url": "https://glygen.org/publication/PubMed/33157024" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "2166", "end_pos": "2166", "site_lbl": "Ser2166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "28637746", "url": "https://glygen.org/publication/PubMed/28637746" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Thr23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Ser304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Ser305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "335", "end_pos": "335", "site_lbl": "Ser335", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "391", "end_pos": "391", "site_lbl": "Ser391", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Thr392", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "437", "end_pos": "437", "site_lbl": "Ser437", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Ser506", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Tyr632", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "639", "end_pos": "639", "site_lbl": "Ser639", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Ser640", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "678", "end_pos": "678", "site_lbl": "Ser678", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "720", "end_pos": "720", "site_lbl": "Ser720", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "729", "end_pos": "729", "site_lbl": "Ser729", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "749", "end_pos": "749", "site_lbl": "Ser749", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Ser752", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "758", "end_pos": "758", "site_lbl": "Ser758", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "760", "end_pos": "760", "site_lbl": "Ser760", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "774", "end_pos": "774", "site_lbl": "Ser774", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "776", "end_pos": "776", "site_lbl": "Ser776", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001915", "url": "https://www.yeastgenome.org/locus/S000001915" }, { "database": "iPTMnet", "id": "P34756", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34756" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1017", "end_pos": "1017", "site_lbl": "Thr1017", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "I", "comment": "Cells are defective for growth at 38 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "18653468", "url": "https://glygen.org/publication/PubMed/18653468" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1243", "end_pos": "1243", "site_lbl": "Cys1243", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Cells are defective for growth at 38 degrees Celsius and show single-lobed, enlarged vacuoles.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "18653468", "url": "https://glygen.org/publication/PubMed/18653468" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1419", "end_pos": "1419", "site_lbl": "Gln1419", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "R", "comment": "Impairs intramolecular interaction with the kinase domain. Leads to elevated PI(3,5)P2 levels.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "28148651", "url": "https://glygen.org/publication/PubMed/28148651" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1486", "end_pos": "1486", "site_lbl": "Asp1486", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Impairs intramolecular interaction with the kinase domain. Leads to elevated PI(3,5)P2 levels.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "28148651", "url": "https://glygen.org/publication/PubMed/28148651" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "1491", "end_pos": "1491", "site_lbl": "Thr1491", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Impairs intramolecular interaction with the kinase domain. Leads to elevated PI(3,5)P2 levels.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "28148651", "url": "https://glygen.org/publication/PubMed/28148651" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "2134", "end_pos": "2134", "site_lbl": "Asp2134", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "R", "comment": "Cells are defective for growth at 38 degrees Celsius. PtdIns(3,5)P2 levels are severely reduced.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "18653468", "url": "https://glygen.org/publication/PubMed/18653468" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "2250", "end_pos": "2250", "site_lbl": "Thr2250", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Impairs intramolecular interaction with the CCR domain, leading to a hyperactive kinase mutant; elevates PI(3,5)P2 levels.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "30427760", "url": "https://glygen.org/publication/PubMed/30427760" }, { "database": "PubMed", "id": "28148651", "url": "https://glygen.org/publication/PubMed/28148651" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "2253", "end_pos": "2253", "site_lbl": "Gln2253", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "R", "comment": "Impairs intramolecular interaction with the CCR domain, leading to a hyperactive kinase mutant.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "28148651", "url": "https://glygen.org/publication/PubMed/28148651" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "2264", "end_pos": "2264", "site_lbl": "Arg2264", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs intramolecular interaction with the CCR domain, leading to a hyperactive kinase mutant.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "28148651", "url": "https://glygen.org/publication/PubMed/28148651" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Cys262", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Cells show growth at 38 degrees Celsius. Failure to localize to the vacuole membrane.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "18653468", "url": "https://glygen.org/publication/PubMed/18653468" } ] } ] }, { "uniprot_canonical_ac": "P34756-1", "start_pos": "864", "end_pos": "864", "site_lbl": "Gly864", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "Loss of interaction with VAC14. Failure to localize to the vacuole membrane.", "evidence": [ { "database": "UniProtKB", "id": "P34756", "url": "https://www.uniprot.org/uniprotkb/P34756" }, { "database": "PubMed", "id": "19037259", "url": "https://glygen.org/publication/PubMed/19037259" } ] } ] } ], "record_id": "P34756-1" }, { "uniprot_canonical_ac": "P34758-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 872, "chemical_mass": 97305.0, "gene_names": "SCD5;FTB1;SCD5;SCD7", "protein_name": "Protein SCD5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" } ], "pmid": "" }, { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" } ], "pmid": "" }, { "name": "positive regulation of clathrin-dependent endocytosis", "id": "GO:2000370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000370", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34758-1", "start_pos": "561", "end_pos": "561", "site_lbl": "Ser561", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 561, "start_aa": "Ser", "end_pos": 561, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser561", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34758", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34758" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005856", "url": "https://www.yeastgenome.org/locus/S000005856" }, { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Ser564", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 564, "start_aa": "Ser", "end_pos": 564, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser564", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34758", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34758" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005856", "url": "https://www.yeastgenome.org/locus/S000005856" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Ser570", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 570, "start_aa": "Ser", "end_pos": 570, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser570", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34758", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34758" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "739", "end_pos": "739", "site_lbl": "Thr739", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 739, "start_aa": "Thr", "end_pos": 739, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr739", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Ser312", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005856", "url": "https://www.yeastgenome.org/locus/S000005856" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Thr416", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" }, { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "13679512", "url": "https://glygen.org/publication/PubMed/13679512" }, { "database": "PubMed", "id": "17898076", "url": "https://glygen.org/publication/PubMed/17898076" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Thr450", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" }, { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "13679512", "url": "https://glygen.org/publication/PubMed/13679512" }, { "database": "PubMed", "id": "17898076", "url": "https://glygen.org/publication/PubMed/17898076" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Thr490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34758", "url": "https://www.uniprot.org/uniprotkb/P34758" }, { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "13679512", "url": "https://glygen.org/publication/PubMed/13679512" }, { "database": "PubMed", "id": "17898076", "url": "https://glygen.org/publication/PubMed/17898076" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005856", "url": "https://www.yeastgenome.org/locus/S000005856" }, { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005856", "url": "https://www.yeastgenome.org/locus/S000005856" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005856", "url": "https://www.yeastgenome.org/locus/S000005856" }, { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005856", "url": "https://www.yeastgenome.org/locus/S000005856" }, { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005856", "url": "https://www.yeastgenome.org/locus/S000005856" }, { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34758-1", "start_pos": "847", "end_pos": "847", "site_lbl": "Ser847", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005856", "url": "https://www.yeastgenome.org/locus/S000005856" }, { "database": "iPTMnet", "id": "P34758", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34758" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P34758-1" }, { "uniprot_canonical_ac": "P34760-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 196, "chemical_mass": 21590.0, "gene_names": "TSA1;TPX1;TSA1;TSA;ZRG14", "protein_name": "Peroxiredoxin TSA1", "disease": [ { "disease_id": "DOID:0050715", "name": "methylmalonic aciduria and homocystinuria type cblC", "description": "A methylmalonic acidemia that has_material_basis_in deficiency in synthesis of both AdoCbl and MeCbl (cblC) and is characterized by decreased levels of the coenzymes adenosylcobalamin (AdoCbl) and methylcobalamin (MeCbl), which results in decreased activity of the respective enzymes methylmalonyl-CoA mutase.", "url": "https://disease-ontology.org/term/DOID:0050715", "evidence": [ { "id": "0050715", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050715" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0070413", "name": "autosomal recessive spinocerebellar ataxia 32", "description": "An autosomal recessive cerebellar ataxia characterized by onset of gait ataxia in the second or third decade of life that has_material_basis_in homozygous or compound heterozygous mutation in the PRDX3 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0070413", "evidence": [ { "id": "0070413", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070413" } ], "weight": 0.0 }, { "disease_id": "DOID:10603", "name": "glucose intolerance", "description": "", "url": "https://disease-ontology.org/term/DOID:10603", "evidence": [ { "id": "10603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10603" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "DNA protection", "id": "GO:0042262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042262", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "hydrogen peroxide catabolic process", "id": "GO:0042744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042744", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "cellular response to hydroperoxide", "id": "GO:0071447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071447", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "protein polymerization", "id": "GO:0051258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051258", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "response to hydroperoxide", "id": "GO:0033194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033194", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "regulation of gluconeogenesis", "id": "GO:0006111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006111", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "cellular response to dithiothreitol", "id": "GO:0072721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072721", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "peroxiredoxin activity", "id": "GO:0051920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051920", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "thioredoxin peroxidase activity", "id": "GO:0008379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008379", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" }, { "name": "kinase regulator activity", "id": "GO:0019207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019207", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34760-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Thr104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004490", "url": "https://www.yeastgenome.org/locus/S000004490" }, { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004490", "url": "https://www.yeastgenome.org/locus/S000004490" }, { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004490", "url": "https://www.yeastgenome.org/locus/S000004490" }, { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Tyr112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Thr11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004490", "url": "https://www.yeastgenome.org/locus/S000004490" }, { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Thr139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004490", "url": "https://www.yeastgenome.org/locus/S000004490" }, { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Thr15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004490", "url": "https://www.yeastgenome.org/locus/S000004490" }, { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Thr174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004490", "url": "https://www.yeastgenome.org/locus/S000004490" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004490", "url": "https://www.yeastgenome.org/locus/S000004490" }, { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004490", "url": "https://www.yeastgenome.org/locus/S000004490" }, { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004490", "url": "https://www.yeastgenome.org/locus/S000004490" }, { "database": "iPTMnet", "id": "P34760", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34760" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Cys171", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Exists mainly as monomer. Has no peroxiredoxin activity.", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" }, { "database": "PubMed", "id": "8041739", "url": "https://glygen.org/publication/PubMed/8041739" }, { "database": "PubMed", "id": "7961686", "url": "https://glygen.org/publication/PubMed/7961686" } ] } ] }, { "uniprot_canonical_ac": "P34760-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Cys48", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Exists mainly as monomer. Has no peroxiredoxin activity. Fails to protect glutamine synthetase against damage by DTT oxidation.", "evidence": [ { "database": "UniProtKB", "id": "P34760", "url": "https://www.uniprot.org/uniprotkb/P34760" }, { "database": "PubMed", "id": "8041739", "url": "https://glygen.org/publication/PubMed/8041739" }, { "database": "PubMed", "id": "7961686", "url": "https://glygen.org/publication/PubMed/7961686" } ] } ] } ], "record_id": "P34760-1" }, { "uniprot_canonical_ac": "P34761-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 661, "chemical_mass": 71253.0, "gene_names": "WHI3;N1382;WHI3", "protein_name": "Protein WHI3", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "positive regulation of cell-substrate adhesion", "id": "GO:0010811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010811", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "positive regulation of cell size", "id": "GO:0045793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045793", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "mRNA destabilization", "id": "GO:0061157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061157", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "positive regulation of translational elongation", "id": "GO:0045901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045901", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "traversing start control point of mitotic cell cycle", "id": "GO:0007089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007089", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "regulation of cell size", "id": "GO:0008361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008361", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "regulation of mRNA catabolic process", "id": "GO:0061013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061013", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "cell wall organization or biogenesis", "id": "GO:0071554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071554", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "invasive growth in response to glucose limitation", "id": "GO:0001403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001403", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" }, { "name": "pseudohyphal growth", "id": "GO:0007124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007124", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P34761-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Ser494", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 494, "start_aa": "Ser", "end_pos": 494, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser494", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34761", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34761" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "499", "end_pos": "499", "site_lbl": "Ser499", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 499, "start_aa": "Ser", "end_pos": 499, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser499", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34761", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34761" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "502", "end_pos": "502", "site_lbl": "Ser502", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 502, "start_aa": "Ser", "end_pos": 502, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser502", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34761", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34761" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Ser504", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 504, "start_aa": "Ser", "end_pos": 504, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser504", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34761", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34761" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "505", "end_pos": "505", "site_lbl": "Ser505", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 505, "start_aa": "Ser", "end_pos": 505, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser505", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34761", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34761" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "510", "end_pos": "510", "site_lbl": "Ser510", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 510, "start_aa": "Ser", "end_pos": 510, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser510", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34761", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34761" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "512", "end_pos": "512", "site_lbl": "Ser512", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 512, "start_aa": "Ser", "end_pos": 512, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser512", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34761", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34761" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "514", "end_pos": "514", "site_lbl": "Ser514", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 514, "start_aa": "Ser", "end_pos": 514, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser514", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34761", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34761" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "519", "end_pos": "519", "site_lbl": "Ser519", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 519, "start_aa": "Ser", "end_pos": 519, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser519", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P34761", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P34761" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Ser228", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P34761", "url": "https://www.uniprot.org/uniprotkb/P34761" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "234", "end_pos": "234", "site_lbl": "Ser234", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Ser298", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Ser31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Tyr472", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Thr479", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Ser489", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005141", "url": "https://www.yeastgenome.org/locus/S000005141" }, { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "491", "end_pos": "491", "site_lbl": "Ser491", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P34761-1", "start_pos": "568", "end_pos": "568", "site_lbl": "Ser568", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P34761", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34761" }, { "database": "PubMed", "id": "23471970", "url": "https://glygen.org/publication/PubMed/23471970" }, { "database": "PubMed", "id": "24096659", "url": "https://glygen.org/publication/PubMed/24096659" } ] } ] } ], "record_id": "P34761-1" }, { "uniprot_canonical_ac": "P35056-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 612, "chemical_mass": 69324.0, "gene_names": "PEX5;PAS10;PEX5;YD8419.11", "protein_name": "Peroxisomal targeting signal receptor", "disease": [ { "disease_id": "DOID:0080377", "name": "peroxisomal biogenesis disorder", "description": "A peroxisomal biogenesis disorder that has_material_basis_in defects in PEX genes.", "url": "https://disease-ontology.org/term/DOID:0080377", "evidence": [ { "id": "0080377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080377" } ], "weight": 0.0 }, { "disease_id": "DOID:0080477", "name": "peroxisome biogenesis disorder 2A", "description": "A Zellweger syndrome that has_material_basis_in homozygous mutation in the PEX5 gene on chromosome 12p13.", "url": "https://disease-ontology.org/term/DOID:0080477", "evidence": [ { "id": "0080477", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080477" } ], "weight": 0.0 }, { "disease_id": "DOID:0080622", "name": "peroxisome biogenesis disorder 2B", "description": "A peroxisomal biogenesis disorder that has_material_basis_in homozygous mutation in the PEX5 gene on chromosome 12p13.3.", "url": "https://disease-ontology.org/term/DOID:0080622", "evidence": [ { "id": "0080622", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080622" } ], "weight": 0.0 }, { "disease_id": "DOID:0110854", "name": "rhizomelic chondrodysplasia punctata type 5", "description": "A rhizomelic chondrodysplasia punctata that has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the PEX5 gene on chromosome 12p13.31.", "url": "https://disease-ontology.org/term/DOID:0110854", "evidence": [ { "id": "0110854", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110854" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "peroxisomal importomer complex", "id": "GO:1990429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990429", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "pmid": "" }, { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "pmid": "" }, { "name": "peroxisome matrix targeting signal-1 binding", "id": "GO:0005052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005052", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "pmid": "" }, { "name": "protein carrier chaperone", "id": "GO:0140597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140597", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "pmid": "" } ], "biological_process": [ { "name": "protein import into peroxisome matrix", "id": "GO:0016558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016558", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix, docking", "id": "GO:0016560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016560", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35056-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Ser180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Ser232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Ser255", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Ser263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Ser274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Ser330", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Ser507", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Ser523", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "568", "end_pos": "568", "site_lbl": "Ser568", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "611", "end_pos": "611", "site_lbl": "Ser611", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002652", "url": "https://www.yeastgenome.org/locus/S000002652" }, { "database": "iPTMnet", "id": "P35056", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35056" }, { "database": "PubMed", "id": "36122347", "url": "https://glygen.org/publication/PubMed/36122347" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Lys18", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of UBE2D2-dependent ubiquitination. No effect on its function. Abolished monoubiquitination by PEX2 and polyubiquitination by PEX10, leading to impaired protein import in peroxisomes; when associated with A-6 and R-24.", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" }, { "database": "PubMed", "id": "17452527", "url": "https://glygen.org/publication/PubMed/17452527" }, { "database": "PubMed", "id": "35768507", "url": "https://glygen.org/publication/PubMed/35768507" }, { "database": "PubMed", "id": "17550898", "url": "https://glygen.org/publication/PubMed/17550898" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Lys24", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of UBE2D2-dependent ubiquitination. No effect on its function. Abolished monoubiquitination by PEX2 and polyubiquitination by PEX10, leading to impaired protein import in peroxisomes; when associated with A-6 and R-18.", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" }, { "database": "PubMed", "id": "17452527", "url": "https://glygen.org/publication/PubMed/17452527" }, { "database": "PubMed", "id": "35768507", "url": "https://glygen.org/publication/PubMed/35768507" }, { "database": "PubMed", "id": "17550898", "url": "https://glygen.org/publication/PubMed/17550898" } ] } ] }, { "uniprot_canonical_ac": "P35056-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Cys6", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "R", "comment": "Abolished monoubiquitination by PEX2, promoting polyubiquitination by PEX10 and degradation. Loss of UBE2D2-independent ubiquitination. Abolished monoubiquitination by PEX2 and polyubiquitination by PEX10, leading to impaired protein import in peroxisomes; when associated with R-18 and R-24.", "evidence": [ { "database": "UniProtKB", "id": "P35056", "url": "https://www.uniprot.org/uniprotkb/P35056" }, { "database": "PubMed", "id": "35768507", "url": "https://glygen.org/publication/PubMed/35768507" }, { "database": "PubMed", "id": "17550898", "url": "https://glygen.org/publication/PubMed/17550898" } ] } ] } ], "record_id": "P35056-1" }, { "uniprot_canonical_ac": "P35177-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1332, "chemical_mass": 152617.0, "gene_names": "SPT7;GIT2;SPT7;YBR0739", "protein_name": "SAGA complex subunit SPT7", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" }, { "name": "SLIK (SAGA-like) complex", "id": "GO:0046695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046695", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" }, { "name": "conjugation with cellular fusion", "id": "GO:0000747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000747", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35177-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Ser100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Thr102", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "1101", "end_pos": "1101", "site_lbl": "Ser1101", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "1206", "end_pos": "1206", "site_lbl": "Ser1206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "1293", "end_pos": "1293", "site_lbl": "Ser1293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "1294", "end_pos": "1294", "site_lbl": "Ser1294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "1299", "end_pos": "1299", "site_lbl": "Thr1299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Ser249", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Ser268", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Ser339", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Ser341", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Thr367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Ser371", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Thr372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Ser374", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Thr621", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "682", "end_pos": "682", "site_lbl": "Thr682", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "690", "end_pos": "690", "site_lbl": "Thr690", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "763", "end_pos": "763", "site_lbl": "Ser763", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "765", "end_pos": "765", "site_lbl": "Ser765", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Thr78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" }, { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "827", "end_pos": "827", "site_lbl": "Ser827", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "846", "end_pos": "846", "site_lbl": "Thr846", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "878", "end_pos": "878", "site_lbl": "Ser878", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Ser88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35177", "url": "https://www.uniprot.org/uniprotkb/P35177" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "930", "end_pos": "930", "site_lbl": "Ser930", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35177-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000285", "url": "https://www.yeastgenome.org/locus/S000000285" }, { "database": "iPTMnet", "id": "P35177", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35177" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P35177-1" }, { "uniprot_canonical_ac": "P35179-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 80, "chemical_mass": 8944.0, "gene_names": "SSS1;D4475;SSS1", "protein_name": "Protein transport protein SSS1", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" }, { "name": "Sec61 translocon complex", "id": "GO:0005784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005784", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum membrane", "id": "GO:0030867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030867", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" }, { "name": "Ssh1 translocon complex", "id": "GO:0071261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071261", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" }, { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" } ], "biological_process": [ { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" }, { "name": "post-translational protein targeting to membrane, translocation", "id": "GO:0031204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031204", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, translocation", "id": "GO:0006616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006616", "evidence": [ { "database": "UniProtKB", "id": "P35179", "url": "https://www.uniprot.org/uniprotkb/P35179" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35179-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002493", "url": "https://www.yeastgenome.org/locus/S000002493" }, { "database": "iPTMnet", "id": "P35179", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35179" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35179-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Tyr66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35179", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35179" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P35179-1" }, { "uniprot_canonical_ac": "P35181-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35181", "url": "https://www.uniprot.org/uniprotkb/P35181" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 156, "chemical_mass": 18152.0, "gene_names": "APS1;APS1;L9470.16;YAP19", "protein_name": "AP-1 complex subunit sigma-1", "disease": [ { "disease_id": "DOID:0060483", "name": "MEDNIK syndrome", "description": "A syndrome characterized by mental retardation, enteropathy, deafness, peripheral neuropathy, ichthyosis, and keratoderma. It is cause by homozygous mutation in the AP1S1 gene on chromosome 7q22.", "url": "https://disease-ontology.org/term/DOID:0060483", "evidence": [ { "id": "0060483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060483" } ], "weight": 0.0 }, { "disease_id": "DOID:0060800", "name": "syndromic X-linked intellectual disability 5", "description": "A syndromic X-linked intellectual disability characterized by intellectual disability and variable features including choreoathetosis, hydrocephalus, Dandy-Walker malformation, seizures, and iron or calcium deposition in the brain that has_material_basis_in mutation in the AP1S2 gene on chromosome Xp22.", "url": "https://disease-ontology.org/term/DOID:0060800", "evidence": [ { "id": "0060800", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060800" } ], "weight": 0.0 }, { "disease_id": "DOID:0111281", "name": "psoriasis 15", "description": "A psoriasis characterized by pustular psoriasis that has_material_basis_in heterozygous mutation in the AP1S3 gene on chromosome 2q36.1.", "url": "https://disease-ontology.org/term/DOID:0111281", "evidence": [ { "id": "0111281", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111281" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P35181", "url": "https://www.uniprot.org/uniprotkb/P35181" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P35181", "url": "https://www.uniprot.org/uniprotkb/P35181" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P35181", "url": "https://www.uniprot.org/uniprotkb/P35181" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "P35181", "url": "https://www.uniprot.org/uniprotkb/P35181" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P35181", "url": "https://www.uniprot.org/uniprotkb/P35181" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "P35181", "url": "https://www.uniprot.org/uniprotkb/P35181" } ], "pmid": "" }, { "name": "vesicle targeting, trans-Golgi to endosome", "id": "GO:0048203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048203", "evidence": [ { "database": "UniProtKB", "id": "P35181", "url": "https://www.uniprot.org/uniprotkb/P35181" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "P35181", "url": "https://www.uniprot.org/uniprotkb/P35181" } ], "pmid": "" } ], "molecular_function": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "P35181", "url": "https://www.uniprot.org/uniprotkb/P35181" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35181-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004160", "url": "https://www.yeastgenome.org/locus/S000004160" }, { "database": "iPTMnet", "id": "P35181", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35181" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P35181-1" }, { "uniprot_canonical_ac": "P35182-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 281, "chemical_mass": 31550.0, "gene_names": "PTC1;CWH47;D2925;KCS2;PTC1;TPD1", "protein_name": "Protein phosphatase 2C homolog 1", "disease": [ { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "MAP kinase serine/threonine phosphatase activity", "id": "GO:1990439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990439", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" }, { "name": "tRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0006388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006388", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" }, { "name": "negative regulation of MAPK cascade", "id": "GO:0043409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043409", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" }, { "name": "mitochondrion inheritance", "id": "GO:0000001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000001", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" }, { "name": "pheromone-dependent signal transduction involved in conjugation with cellular fusion", "id": "GO:0000750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000750", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" }, { "name": "fungal-type cell wall organization or biogenesis", "id": "GO:0071852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071852", "evidence": [ { "database": "UniProtKB", "id": "P35182", "url": "https://www.uniprot.org/uniprotkb/P35182" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35182-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35182" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002164", "url": "https://www.yeastgenome.org/locus/S000002164" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35182-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35182" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002164", "url": "https://www.yeastgenome.org/locus/S000002164" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35182-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Thr13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002164", "url": "https://www.yeastgenome.org/locus/S000002164" }, { "database": "iPTMnet", "id": "P35182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35182" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35182-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Thr173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002164", "url": "https://www.yeastgenome.org/locus/S000002164" }, { "database": "iPTMnet", "id": "P35182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35182" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35182-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002164", "url": "https://www.yeastgenome.org/locus/S000002164" }, { "database": "iPTMnet", "id": "P35182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35182" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35182-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002164", "url": "https://www.yeastgenome.org/locus/S000002164" }, { "database": "iPTMnet", "id": "P35182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35182" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P35182-1" }, { "uniprot_canonical_ac": "P35191-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 511, "chemical_mass": 55561.0, "gene_names": "MDJ1;MDJ1", "protein_name": "DnaJ homolog 1, mitochondrial", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" } ], "biological_process": [ { "name": "response to heat", "id": "GO:0009408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009408", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" }, { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" }, { "name": "protein quality control for misfolded or incompletely synthesized proteins", "id": "GO:0006515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006515", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" }, { "name": "'de novo' protein folding", "id": "GO:0006458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006458", "evidence": [ { "database": "UniProtKB", "id": "P35191", "url": "https://www.uniprot.org/uniprotkb/P35191" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35191-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Thr300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001878", "url": "https://www.yeastgenome.org/locus/S000001878" }, { "database": "iPTMnet", "id": "P35191", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35191" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P35191-1" }, { "uniprot_canonical_ac": "P35192-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 417, "chemical_mass": 46516.0, "gene_names": "MAC1;CUA1;MAC1;YM9711.11C", "protein_name": "Metal-binding activator 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" }, { "name": "intracellular copper ion homeostasis", "id": "GO:0006878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006878", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" }, { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35192-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004623", "url": "https://www.yeastgenome.org/locus/S000004623" }, { "database": "iPTMnet", "id": "P35192", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35192" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35192-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Thr139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35192", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35192" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P35192-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Thr141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004623", "url": "https://www.yeastgenome.org/locus/S000004623" }, { "database": "iPTMnet", "id": "P35192", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35192" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35192-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Ser143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35192", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35192" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004623", "url": "https://www.yeastgenome.org/locus/S000004623" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35192-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Ser146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004623", "url": "https://www.yeastgenome.org/locus/S000004623" }, { "database": "iPTMnet", "id": "P35192", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35192" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35192-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Thr147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004623", "url": "https://www.yeastgenome.org/locus/S000004623" }, { "database": "iPTMnet", "id": "P35192", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35192" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35192-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004623", "url": "https://www.yeastgenome.org/locus/S000004623" }, { "database": "iPTMnet", "id": "P35192", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35192" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P35192-1", "start_pos": "279", "end_pos": "279", "site_lbl": "His279", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Q", "comment": "Gain of function.", "evidence": [ { "database": "UniProtKB", "id": "P35192", "url": "https://www.uniprot.org/uniprotkb/P35192" }, { "database": "PubMed", "id": "8262047", "url": "https://glygen.org/publication/PubMed/8262047" } ] } ] } ], "record_id": "P35192-1" }, { "uniprot_canonical_ac": "P35194-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 2493, "chemical_mass": 287560.0, "gene_names": "UTP20;UTP20;YBL0101", "protein_name": "U3 small nucleolar RNA-associated protein 20", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" } ], "biological_process": [ { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "P35194", "url": "https://www.uniprot.org/uniprotkb/P35194" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35194-1", "start_pos": "938", "end_pos": "938", "site_lbl": "Thr938", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 938, "start_aa": "Thr", "end_pos": 938, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr938", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P35194-1", "start_pos": "1577", "end_pos": "1577", "site_lbl": "Ser1577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35194" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000100", "url": "https://www.yeastgenome.org/locus/S000000100" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35194-1", "start_pos": "1605", "end_pos": "1605", "site_lbl": "Thr1605", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000100", "url": "https://www.yeastgenome.org/locus/S000000100" }, { "database": "iPTMnet", "id": "P35194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35194" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35194-1", "start_pos": "1825", "end_pos": "1825", "site_lbl": "Ser1825", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000100", "url": "https://www.yeastgenome.org/locus/S000000100" }, { "database": "iPTMnet", "id": "P35194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35194" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35194-1", "start_pos": "1827", "end_pos": "1827", "site_lbl": "Ser1827", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000100", "url": "https://www.yeastgenome.org/locus/S000000100" }, { "database": "iPTMnet", "id": "P35194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35194" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35194-1", "start_pos": "2410", "end_pos": "2410", "site_lbl": "Ser2410", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000100", "url": "https://www.yeastgenome.org/locus/S000000100" }, { "database": "iPTMnet", "id": "P35194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35194" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35194-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Thr515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000100", "url": "https://www.yeastgenome.org/locus/S000000100" }, { "database": "iPTMnet", "id": "P35194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35194" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P35194-1", "start_pos": "521", "end_pos": "521", "site_lbl": "Thr521", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000100", "url": "https://www.yeastgenome.org/locus/S000000100" }, { "database": "iPTMnet", "id": "P35194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35194" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P35194-1", "start_pos": "533", "end_pos": "533", "site_lbl": "Ser533", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000100", "url": "https://www.yeastgenome.org/locus/S000000100" }, { "database": "iPTMnet", "id": "P35194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35194" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35194-1", "start_pos": "822", "end_pos": "822", "site_lbl": "Ser822", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000100", "url": "https://www.yeastgenome.org/locus/S000000100" }, { "database": "iPTMnet", "id": "P35194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35194" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P35194-1" }, { "uniprot_canonical_ac": "P35196-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 286, "chemical_mass": 32694.0, "gene_names": "RER2;RER2;YBR0107", "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit RER2", "disease": [ { "disease_id": "DOID:0080473", "name": "developmental delay and seizures with or without movement abnormalities", "description": "A syndromic intellectual disability characterized by global developmental delay, variable intellectual disability, and early-onset seizures with a myoclonic component that has_material_basis_in heterozygous mutation in the DHDDS gene on chromosome 1p36.", "url": "https://disease-ontology.org/term/DOID:0080473", "evidence": [ { "id": "0080473", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080473" } ], "weight": 0.0 }, { "disease_id": "DOID:0110352", "name": "retinitis pigmentosa 59", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the DHDDS gene on chromosome 1p36.11.", "url": "https://disease-ontology.org/term/DOID:0110352", "evidence": [ { "id": "0110352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110352" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "pmid": "" }, { "name": "dehydrodolichyl diphosphate synthase complex", "id": "GO:1904423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904423", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "pmid": "" } ], "biological_process": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "pmid": "" }, { "name": "dolichyl monophosphate biosynthetic process", "id": "GO:0043048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043048", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "pmid": "" }, { "name": "polyprenol biosynthetic process", "id": "GO:0016094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016094", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "pmid": "" } ], "molecular_function": [ { "name": "prenyltransferase activity", "id": "GO:0004659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004659", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "pmid": "" }, { "name": "ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity", "id": "GO:0045547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045547", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35196-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Ser223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000206", "url": "https://www.yeastgenome.org/locus/S000000206" }, { "database": "iPTMnet", "id": "P35196", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35196" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35196-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000206", "url": "https://www.yeastgenome.org/locus/S000000206" }, { "database": "iPTMnet", "id": "P35196", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35196" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35196-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Gly164", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In RER2-1; loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ] } ] }, { "uniprot_canonical_ac": "P35196-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Ser209", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "N", "comment": "In RER2-2; loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P35196", "url": "https://www.uniprot.org/uniprotkb/P35196" } ] } ] } ], "record_id": "P35196-1" }, { "uniprot_canonical_ac": "P35197-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 352, "chemical_mass": 39296.0, "gene_names": "GCS1;GCS1", "protein_name": "ADP-ribosylation factor GTPase-activating protein GCS1", "disease": [], "biological_process": [ { "name": "COPI coating of Golgi vesicle", "id": "GO:0048205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048205", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35197-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Thr10", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 10, "start_aa": "Thr", "end_pos": 10, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr10", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P35197", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P35197" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Thr151", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Thr217", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 217, "start_aa": "Thr", "end_pos": 217, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 2, "start_aa": "Ser", "end_pos": 2, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P35197", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P35197" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Thr146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Thr161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Thr170", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Thr232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "234", "end_pos": "234", "site_lbl": "Ser234", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Ser255", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Ser260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Ser278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Ser321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Ser322", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "323", "end_pos": "323", "site_lbl": "Thr323", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Thr328", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Thr67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35197", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35197" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002385", "url": "https://www.yeastgenome.org/locus/S000002385" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35197-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Cys29", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "Y", "comment": "In GCS1-1; severely affect the function.", "evidence": [ { "database": "UniProtKB", "id": "P35197", "url": "https://www.uniprot.org/uniprotkb/P35197" }, { "database": "PubMed", "id": "8070409", "url": "https://glygen.org/publication/PubMed/8070409" } ] } ] } ], "record_id": "P35197-1" }, { "uniprot_canonical_ac": "P35201-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 549, "chemical_mass": 62473.0, "gene_names": "MIF2;MIF2", "protein_name": "Inner kinetochore subunit MIF2", "disease": [ { "disease_id": "DOID:0060218", "name": "CREST syndrome", "description": "A syndrome characterized by calcinosis, Raynaud's phenomeno, esophageal dysmotility, sclerodactyly and telangiectasia.", "url": "https://disease-ontology.org/term/DOID:0060218", "evidence": [ { "id": "0060218", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060218" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 } ], "biological_process": [ { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" }, { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" }, { "name": "spindle attachment to meiosis I kinetochore", "id": "GO:0051455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051455", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" }, { "name": "condensed chromosome, centromeric region", "id": "GO:0000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000779", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" }, { "name": "centromeric DNA binding", "id": "GO:0019237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019237", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35201-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Thr134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Thr144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Ser154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "14581449", "url": "https://glygen.org/publication/PubMed/14581449" }, { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Thr166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Thr321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Tyr322", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Ser325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35201", "url": "https://www.uniprot.org/uniprotkb/P35201" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "14581449", "url": "https://glygen.org/publication/PubMed/14581449" }, { "database": "PubMed", "id": "21633108", "url": "https://glygen.org/publication/PubMed/21633108" }, { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Thr355", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "7628703", "url": "https://glygen.org/publication/PubMed/7628703" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Ser387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Ser54", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "14581449", "url": "https://glygen.org/publication/PubMed/14581449" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Ser86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Ser88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" }, { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P35201-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Ser98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35201", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35201" }, { "database": "PubMed", "id": "14581449", "url": "https://glygen.org/publication/PubMed/14581449" }, { "database": "SGD", "id": "S000001572", "url": "https://www.yeastgenome.org/locus/S000001572" } ] } ] } ], "record_id": "P35201-1" }, { "uniprot_canonical_ac": "P35203-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35203", "url": "https://www.uniprot.org/uniprotkb/P35203" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 478, "chemical_mass": 56336.0, "gene_names": "CTF13;CBF3C;CTF13;YM6543.01;YM9582.19", "protein_name": "Centromere DNA-binding protein complex CBF3 subunit C", "disease": [], "biological_process": [ { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "P35203", "url": "https://www.uniprot.org/uniprotkb/P35203" } ], "pmid": "" }, { "name": "septin ring assembly", "id": "GO:0000921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000921", "evidence": [ { "database": "UniProtKB", "id": "P35203", "url": "https://www.uniprot.org/uniprotkb/P35203" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding, bending", "id": "GO:0008301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008301", "evidence": [ { "database": "UniProtKB", "id": "P35203", "url": "https://www.uniprot.org/uniprotkb/P35203" } ], "pmid": "" } ], "cellular_component": [ { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P35203", "url": "https://www.uniprot.org/uniprotkb/P35203" } ], "pmid": "" }, { "name": "CBF3 complex", "id": "GO:0031518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031518", "evidence": [ { "database": "UniProtKB", "id": "P35203", "url": "https://www.uniprot.org/uniprotkb/P35203" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35203-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35203", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35203" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004700", "url": "https://www.yeastgenome.org/locus/S000004700" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35203-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004700", "url": "https://www.yeastgenome.org/locus/S000004700" }, { "database": "iPTMnet", "id": "P35203", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35203" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35203-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004700", "url": "https://www.yeastgenome.org/locus/S000004700" }, { "database": "iPTMnet", "id": "P35203", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35203" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P35203-1" }, { "uniprot_canonical_ac": "P35206-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 410, "chemical_mass": 45442.0, "gene_names": "CSG2;CLS2;CSG2;YBR0404", "protein_name": "Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2", "disease": [ { "disease_id": "DOID:10595", "name": "Charcot-Marie-Tooth disease", "description": "A neuromuscular disease that is characterized by a slowly progressive degeneration of the muscles of the foot, lower leg, hand and forearm.", "url": "https://disease-ontology.org/term/DOID:10595", "evidence": [ { "id": "10595", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10595" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" } ], "biological_process": [ { "name": "glycosphingolipid biosynthetic process", "id": "GO:0006688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006688", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" }, { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol by endoplasmic reticulum", "id": "GO:1903514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903514", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" }, { "name": "mannosyl diphosphorylinositol ceramide metabolic process", "id": "GO:0006676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006676", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" }, { "name": "intracellularly gated calcium channel activity", "id": "GO:0015278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015278", "evidence": [ { "database": "UniProtKB", "id": "P35206", "url": "https://www.uniprot.org/uniprotkb/P35206" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35206-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Asn35", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 35, "start_aa": "Asn", "end_pos": 35, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn35", "evidence": [ { "id": "P35206", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35206#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P35206-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Asn49", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 49, "start_aa": "Asn", "end_pos": 49, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn49", "evidence": [ { "id": "P35206", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35206#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P35206-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Ser101", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000240", "url": "https://www.yeastgenome.org/locus/S000000240" }, { "database": "iPTMnet", "id": "P35206", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35206" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P35206-1" }, { "uniprot_canonical_ac": "P35208-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 640, "chemical_mass": 72922.0, "gene_names": "SPT10;CRE1;J0702;SPT10;SUD1", "protein_name": "Protein SPT10", "disease": [], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" }, { "name": "rDNA heterochromatin formation", "id": "GO:0000183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000183", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" } ], "molecular_function": [ { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" }, { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35208-1", "start_pos": "457", "end_pos": "457", "site_lbl": "Thr457", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 457, "start_aa": "Thr", "end_pos": 457, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr457", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P35208-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003663", "url": "https://www.yeastgenome.org/locus/S000003663" }, { "database": "iPTMnet", "id": "P35208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35208" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P35208-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Ser363", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003663", "url": "https://www.yeastgenome.org/locus/S000003663" }, { "database": "iPTMnet", "id": "P35208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35208" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35208-1", "start_pos": "474", "end_pos": "474", "site_lbl": "Ser474", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003663", "url": "https://www.yeastgenome.org/locus/S000003663" }, { "database": "iPTMnet", "id": "P35208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35208" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35208-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Ser518", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003663", "url": "https://www.yeastgenome.org/locus/S000003663" }, { "database": "iPTMnet", "id": "P35208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35208" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35208-1", "start_pos": "558", "end_pos": "558", "site_lbl": "Ser558", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003663", "url": "https://www.yeastgenome.org/locus/S000003663" }, { "database": "iPTMnet", "id": "P35208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35208" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35208-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Ser613", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003663", "url": "https://www.yeastgenome.org/locus/S000003663" }, { "database": "iPTMnet", "id": "P35208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35208" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35208-1", "start_pos": "619", "end_pos": "619", "site_lbl": "Ser619", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003663", "url": "https://www.yeastgenome.org/locus/S000003663" }, { "database": "iPTMnet", "id": "P35208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35208" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35208-1", "start_pos": "636", "end_pos": "636", "site_lbl": "Ser636", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003663", "url": "https://www.yeastgenome.org/locus/S000003663" }, { "database": "iPTMnet", "id": "P35208", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35208" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P35208-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Cys388", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Loss of complementation of the suppression phenotype.", "evidence": [ { "database": "UniProtKB", "id": "P35208", "url": "https://www.uniprot.org/uniprotkb/P35208" }, { "database": "PubMed", "id": "8138180", "url": "https://glygen.org/publication/PubMed/8138180" } ] } ] } ], "record_id": "P35208-1" }, { "uniprot_canonical_ac": "P35688-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1017, "chemical_mass": 116651.0, "gene_names": "LRG1;LRG1", "protein_name": "Rho-GTPase-activating protein LRG1", "disease": [ { "disease_id": "DOID:0110318", "name": "hypertrophic cardiomyopathy 12", "description": "A familial hypertrophic cardiomyopathy that has_material_basis_in heterozygous mutation in the CSRP3 gene on chromosome 11p15.", "url": "https://disease-ontology.org/term/DOID:0110318", "evidence": [ { "id": "0110318", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110318" } ], "weight": 0.0 }, { "disease_id": "DOID:0110449", "name": "dilated cardiomyopathy 1M", "description": "A dilated cardiomyopathy that has_material_basis_in mutation in the CSRP3 gene on chromosome 11p15.", "url": "https://disease-ontology.org/term/DOID:0110449", "evidence": [ { "id": "0110449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110449" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "site of polarized growth", "id": "GO:0030427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030427", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "cytogamy", "id": "GO:0000755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000755", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "regulation of fungal-type cell wall organization", "id": "GO:0060237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060237", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" }, { "name": "regulation of cell wall (1->3)-beta-D-glucan biosynthetic process", "id": "GO:0090334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090334", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35688-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Thr18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Ser303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Ser522", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "562", "end_pos": "562", "site_lbl": "Ser562", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35688", "url": "https://www.uniprot.org/uniprotkb/P35688" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "567", "end_pos": "567", "site_lbl": "Thr567", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Thr570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "592", "end_pos": "592", "site_lbl": "Ser592", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "593", "end_pos": "593", "site_lbl": "Ser593", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "993", "end_pos": "993", "site_lbl": "Ser993", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35688-1", "start_pos": "999", "end_pos": "999", "site_lbl": "Thr999", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002399", "url": "https://www.yeastgenome.org/locus/S000002399" }, { "database": "iPTMnet", "id": "P35688", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35688" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P35688-1" }, { "uniprot_canonical_ac": "P35691-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 167, "chemical_mass": 18741.0, "gene_names": "TMA19;MMI1;TMA19;YKL312", "protein_name": "Translationally-controlled tumor protein homolog", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35691-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Thr115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001539", "url": "https://www.yeastgenome.org/locus/S000001539" }, { "database": "iPTMnet", "id": "P35691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35691-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35691" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P35691-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35691" }, { "database": "SGD", "id": "S000001539", "url": "https://www.yeastgenome.org/locus/S000001539" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35691-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Tyr18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001539", "url": "https://www.yeastgenome.org/locus/S000001539" }, { "database": "iPTMnet", "id": "P35691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35691-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001539", "url": "https://www.yeastgenome.org/locus/S000001539" }, { "database": "iPTMnet", "id": "P35691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35691" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35691-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001539", "url": "https://www.yeastgenome.org/locus/S000001539" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35691-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Thr85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001539", "url": "https://www.yeastgenome.org/locus/S000001539" }, { "database": "iPTMnet", "id": "P35691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35691" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35691-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Tyr86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001539", "url": "https://www.yeastgenome.org/locus/S000001539" }, { "database": "iPTMnet", "id": "P35691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35691-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35691", "url": "https://www.uniprot.org/uniprotkb/P35691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001539", "url": "https://www.yeastgenome.org/locus/S000001539" }, { "database": "iPTMnet", "id": "P35691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P35691-1" }, { "uniprot_canonical_ac": "P35728-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 441, "chemical_mass": 49647.0, "gene_names": "MPE1;MPE1;YKL316", "protein_name": "Protein MPE1", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" }, { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription", "id": "GO:0006369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006369", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription, poly(A)-coupled", "id": "GO:0030846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030846", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35728-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Thr118", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 118, "start_aa": "Thr", "end_pos": 118, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr118", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P35728", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P35728" } ] } ] }, { "uniprot_canonical_ac": "P35728-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Thr120", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 120, "start_aa": "Thr", "end_pos": 120, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr120", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P35728", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P35728" } ] } ] }, { "uniprot_canonical_ac": "P35728-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Thr121", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 121, "start_aa": "Thr", "end_pos": 121, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr121", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P35728", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P35728" } ] } ] }, { "uniprot_canonical_ac": "P35728-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Thr122", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 122, "start_aa": "Thr", "end_pos": 122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P35728", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P35728" } ] } ] }, { "uniprot_canonical_ac": "P35728-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 126, "start_aa": "Ser", "end_pos": 126, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser126", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P35728", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P35728" } ] } ] }, { "uniprot_canonical_ac": "P35728-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Ser199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001542", "url": "https://www.yeastgenome.org/locus/S000001542" }, { "database": "iPTMnet", "id": "P35728", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35728" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35728-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Thr212", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35728", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35728" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P35728-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35728", "url": "https://www.uniprot.org/uniprotkb/P35728" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35728", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35728" }, { "database": "SGD", "id": "S000001542", "url": "https://www.yeastgenome.org/locus/S000001542" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35728-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001542", "url": "https://www.yeastgenome.org/locus/S000001542" }, { "database": "iPTMnet", "id": "P35728", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35728" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35728-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001542", "url": "https://www.yeastgenome.org/locus/S000001542" }, { "database": "iPTMnet", "id": "P35728", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35728" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35728-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001542", "url": "https://www.yeastgenome.org/locus/S000001542" }, { "database": "iPTMnet", "id": "P35728", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35728" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P35728-1" }, { "uniprot_canonical_ac": "P35729-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1037, "chemical_mass": 120448.0, "gene_names": "NUP120;NUP120;RAT2;YKL313;YKL314", "protein_name": "Nucleoporin NUP120", "disease": [ { "disease_id": "DOID:0080394", "name": "nephrotic syndrome type 19", "description": "A familial nephrotic syndrome that has_material_basis_in compound heterozygous mutation in the NUP160 gene on chromosome 11p11.", "url": "https://disease-ontology.org/term/DOID:0080394", "evidence": [ { "id": "0080394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080394" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "mRNA export from nucleus in response to heat stress", "id": "GO:0031990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031990", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000973", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "telomere tethering at nuclear periphery", "id": "GO:0034398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034398", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "nuclear pore localization", "id": "GO:0051664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051664", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore outer ring", "id": "GO:0031080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" }, { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35729-1", "start_pos": "391", "end_pos": "391", "site_lbl": "Ser391", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001540", "url": "https://www.yeastgenome.org/locus/S000001540" }, { "database": "iPTMnet", "id": "P35729", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35729" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35729-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Thr417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35729", "url": "https://www.uniprot.org/uniprotkb/P35729" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35729", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35729" }, { "database": "SGD", "id": "S000001540", "url": "https://www.yeastgenome.org/locus/S000001540" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35729-1", "start_pos": "814", "end_pos": "814", "site_lbl": "Thr814", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35729", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35729" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P35729-1", "start_pos": "819", "end_pos": "819", "site_lbl": "Tyr819", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35729", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35729" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] } ], "record_id": "P35729-1" }, { "uniprot_canonical_ac": "P35732-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 738, "chemical_mass": 83973.0, "gene_names": "DEF1;DEF1;RIP1;VID31;YKL308", "protein_name": "RNA polymerase II degradation factor 1", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "transcription-coupled nucleotide-excision repair", "id": "GO:0006283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006283", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "regulation of protein complex stability", "id": "GO:0061635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061635", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "transcription factor TFIIH holo complex binding", "id": "GO:0062058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062058", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35732-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Thr133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Ser178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Ser227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Ser243", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Thr249", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Thr258", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Ser260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ser273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Thr338", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "357", "end_pos": "357", "site_lbl": "Thr357", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Ser494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "497", "end_pos": "497", "site_lbl": "Ser497", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "638", "end_pos": "638", "site_lbl": "Thr638", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35732", "url": "https://www.uniprot.org/uniprotkb/P35732" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35732-1", "start_pos": "658", "end_pos": "658", "site_lbl": "Ser658", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001537", "url": "https://www.yeastgenome.org/locus/S000001537" }, { "database": "iPTMnet", "id": "P35732", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35732" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P35732-1" }, { "uniprot_canonical_ac": "P35817-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 686, "chemical_mass": 76978.0, "gene_names": "BDF1;BDF1;L8084.18", "protein_name": "Bromodomain-containing factor 1", "disease": [ { "disease_id": "DOID:0050156", "name": "idiopathic pulmonary fibrosis", "description": "A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe.", "url": "https://disease-ontology.org/term/DOID:0050156", "evidence": [ { "id": "0050156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050156" } ], "weight": 0.0 }, { "disease_id": "DOID:0060970", "name": "Cornelia de Lange syndrome 6", "description": "A Cornelia de Lange syndrome characterized by malformations affecting multiple systems that has_material_basis_in heterozygous mutation in the BRD4 gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0060970", "evidence": [ { "id": "0060970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060970" } ], "weight": 0.0 }, { "disease_id": "DOID:0070163", "name": "spermatogenic failure 21", "description": "A male infertility due to acephalic spermatozoa that is characterized by acephalic spermatozoa, reduced sperm number and impaired sperm motility that has_material_basis_in homozygous mutation in the BRDT gene on chromosome 1p22.", "url": "https://disease-ontology.org/term/DOID:0070163", "evidence": [ { "id": "0070163", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070163" } ], "weight": 0.0 }, { "disease_id": "DOID:0080630", "name": "B-lymphoblastic leukemia/lymphoma", "description": "A B-cell acute lymphoblastic leukemia that is characterized by the presence of too many B-cell lymphoblasts in the blood and bone marrow.", "url": "https://disease-ontology.org/term/DOID:0080630", "evidence": [ { "id": "0080630", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080630" } ], "weight": 0.0 }, { "disease_id": "DOID:12679", "name": "nephrocalcinosis", "description": "", "url": "https://disease-ontology.org/term/DOID:12679", "evidence": [ { "id": "12679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12679" } ], "weight": 0.0 }, { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 }, { "disease_id": "DOID:14228", "name": "oligospermia", "description": "A male fertility issue defined as a low sperm concentration in the ejaculate.", "url": "https://disease-ontology.org/term/DOID:14228", "evidence": [ { "id": "14228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14228" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:3159", "name": "photosensitivity disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3159", "evidence": [ { "id": "3159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3159" } ], "weight": 0.0 }, { "disease_id": "DOID:3969", "name": "papillary thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer and arises from the follicular cells of the thyroid gland.", "url": "https://disease-ontology.org/term/DOID:3969", "evidence": [ { "id": "3969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3969" } ], "weight": 0.0 }, { "disease_id": "DOID:4890", "name": "juvenile myoclonic epilepsy", "description": "A adolescence-adult electroclinical syndrome that is characterized by brief, involuntary twitching of a muscle or a group of muscles (myoclonus) early in the morning with onset between 12 and 18 years.", "url": "https://disease-ontology.org/term/DOID:4890", "evidence": [ { "id": "4890", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4890" } ], "weight": 0.0 }, { "disease_id": "DOID:707", "name": "B-cell lymphoma", "description": "A non-Hodgkin lymphoma that has_material_basis_in B cells.", "url": "https://disease-ontology.org/term/DOID:707", "evidence": [ { "id": "707", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:707" } ], "weight": 0.0 } ], "biological_process": [ { "name": "snRNA transcription", "id": "GO:0009301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009301", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "negative regulation of heterochromatin formation", "id": "GO:0031452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031452", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "regulation of silent mating-type cassette heterochromatin formation", "id": "GO:0090054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090054", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "TFIID-class transcription factor complex binding", "id": "GO:0001094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001094", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "histone H4 reader activity", "id": "GO:0140008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140008", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "histone H3 reader activity", "id": "GO:0140006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140006", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35817-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Ser270", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Ser429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "598", "end_pos": "598", "site_lbl": "Ser598", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "605", "end_pos": "605", "site_lbl": "Ser605", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "612", "end_pos": "612", "site_lbl": "Ser612", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Ser613", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "615", "end_pos": "615", "site_lbl": "Ser615", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "617", "end_pos": "617", "site_lbl": "Thr617", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "618", "end_pos": "618", "site_lbl": "Ser618", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Ser621", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Ser626", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "630", "end_pos": "630", "site_lbl": "Ser630", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "635", "end_pos": "635", "site_lbl": "Ser635", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "650", "end_pos": "650", "site_lbl": "Ser650", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Ser652", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "659", "end_pos": "659", "site_lbl": "Ser659", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Thr90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "92", "end_pos": "92", "site_lbl": "Ser92", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004391", "url": "https://www.yeastgenome.org/locus/S000004391" }, { "database": "iPTMnet", "id": "P35817", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35817" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Tyr187", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Impairs interaction with histones H3 and H4; when associated with F-354.", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" }, { "database": "PubMed", "id": "12620225", "url": "https://glygen.org/publication/PubMed/12620225" } ] } ] }, { "uniprot_canonical_ac": "P35817-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Tyr354", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Impairs interaction with histones H3 and H4; when associated with F-187.", "evidence": [ { "database": "UniProtKB", "id": "P35817", "url": "https://www.uniprot.org/uniprotkb/P35817" }, { "database": "PubMed", "id": "12620225", "url": "https://glygen.org/publication/PubMed/12620225" } ] } ] } ], "record_id": "P35817-1" }, { "uniprot_canonical_ac": "P35843-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 434, "chemical_mass": 49505.0, "gene_names": "HES1;HES1;O5234;OSH5", "protein_name": "Oxysterol-binding protein homolog 5", "disease": [ { "disease_id": "DOID:0110588", "name": "autosomal dominant nonsyndromic deafness 67", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in mutation in the OSBPL2 gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0110588", "evidence": [ { "id": "0110588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110588" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "oxysterol binding", "id": "GO:0008142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008142", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" }, { "name": "sterol transfer activity", "id": "GO:0120015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120015", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" }, { "name": "sterol biosynthetic process", "id": "GO:0016126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016126", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" }, { "name": "maintenance of cell polarity", "id": "GO:0030011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030011", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" }, { "name": "sterol transport", "id": "GO:0015918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015918", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35843-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Ser389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35843", "url": "https://www.uniprot.org/uniprotkb/P35843" } ] } ] } ], "record_id": "P35843-1" }, { "uniprot_canonical_ac": "P35845-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1188, "chemical_mass": 135098.0, "gene_names": "SWH1;OSH1;SWH1;YAR044W", "protein_name": "Oxysterol-binding protein homolog 1", "disease": [ { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus-vacuole junction", "id": "GO:0071561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071561", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "Golgi trans cisterna", "id": "GO:0000138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000138", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "maintenance of cell polarity", "id": "GO:0030011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030011", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "sterol transport", "id": "GO:0015918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015918", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "sterol binding", "id": "GO:0032934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032934", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" }, { "name": "sterol transfer activity", "id": "GO:0120015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120015", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35845-1", "start_pos": "1053", "end_pos": "1053", "site_lbl": "Thr1053", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "1056", "end_pos": "1056", "site_lbl": "Ser1056", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "1172", "end_pos": "1172", "site_lbl": "Tyr1172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Tyr393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Ser394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Ser400", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Ser408", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "423", "end_pos": "423", "site_lbl": "Ser423", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "427", "end_pos": "427", "site_lbl": "Ser427", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Thr430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "432", "end_pos": "432", "site_lbl": "Thr432", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "442", "end_pos": "442", "site_lbl": "Ser442", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "443", "end_pos": "443", "site_lbl": "Thr443", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "474", "end_pos": "474", "site_lbl": "Ser474", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "486", "end_pos": "486", "site_lbl": "Ser486", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Ser488", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Ser492", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Thr495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "500", "end_pos": "500", "site_lbl": "Ser500", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Ser503", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Ser506", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Ser507", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "566", "end_pos": "566", "site_lbl": "Ser566", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "672", "end_pos": "672", "site_lbl": "Thr672", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "678", "end_pos": "678", "site_lbl": "Ser678", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "683", "end_pos": "683", "site_lbl": "Ser683", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "688", "end_pos": "688", "site_lbl": "Ser688", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "691", "end_pos": "691", "site_lbl": "Ser691", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "692", "end_pos": "692", "site_lbl": "Thr692", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "694", "end_pos": "694", "site_lbl": "Thr694", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "705", "end_pos": "705", "site_lbl": "Thr705", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "708", "end_pos": "708", "site_lbl": "Ser708", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "712", "end_pos": "712", "site_lbl": "Ser712", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "725", "end_pos": "725", "site_lbl": "Ser725", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "732", "end_pos": "732", "site_lbl": "Ser732", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "756", "end_pos": "756", "site_lbl": "Ser756", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "762", "end_pos": "762", "site_lbl": "Ser762", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "776", "end_pos": "776", "site_lbl": "Ser776", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "825", "end_pos": "825", "site_lbl": "Thr825", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "826", "end_pos": "826", "site_lbl": "Ser826", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000081", "url": "https://www.yeastgenome.org/locus/S000000081" }, { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "966", "end_pos": "966", "site_lbl": "Thr966", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P35845", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35845" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P35845-1", "start_pos": "719", "end_pos": "719", "site_lbl": "Asp719", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes function.", "evidence": [ { "database": "UniProtKB", "id": "P35845", "url": "https://www.uniprot.org/uniprotkb/P35845" }, { "database": "PubMed", "id": "12727870", "url": "https://glygen.org/publication/PubMed/12727870" } ] } ] } ], "record_id": "P35845-1" }, { "uniprot_canonical_ac": "P35997-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35997", "url": "https://www.uniprot.org/uniprotkb/P35997" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 82, "chemical_mass": 8879.0, "gene_names": "RPS27A;RPS27A", "protein_name": "Small ribosomal subunit protein eS27A", "disease": [ { "disease_id": "DOID:0111880", "name": "Diamond-Blackfan anemia 17", "description": "A Diamond-Blackfan anemia that has_material_basis_in heterozygous mutation in the RPS27 gene on chromosome 1q21.3.", "url": "https://disease-ontology.org/term/DOID:0111880", "evidence": [ { "id": "0111880", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111880" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P35997", "url": "https://www.uniprot.org/uniprotkb/P35997" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P35997", "url": "https://www.uniprot.org/uniprotkb/P35997" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P35997", "url": "https://www.uniprot.org/uniprotkb/P35997" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P35997", "url": "https://www.uniprot.org/uniprotkb/P35997" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P35997", "url": "https://www.uniprot.org/uniprotkb/P35997" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P35997", "url": "https://www.uniprot.org/uniprotkb/P35997" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P35997", "url": "https://www.uniprot.org/uniprotkb/P35997" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "P35997", "url": "https://www.uniprot.org/uniprotkb/P35997" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "P35997", "url": "https://www.uniprot.org/uniprotkb/P35997" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P35997-1" }, { "uniprot_canonical_ac": "P35999-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 772, "chemical_mass": 88183.0, "gene_names": "OCT1;MIP1;OCT1", "protein_name": "Mitochondrial intermediate peptidase", "disease": [ { "disease_id": "DOID:0111488", "name": "combined oxidative phosphorylation deficiency 31", "description": "A combined oxidative phosphorylation deficiency characterized by global developmental delay, severe hypotonia, and left ventricular non-compaction that has_material_basis_in homozygous or compound heterozygous mutation in the MIPEP gene on chromosome 13q12.12.", "url": "https://disease-ontology.org/term/DOID:0111488", "evidence": [ { "id": "0111488", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111488" } ], "weight": 0.0 }, { "disease_id": "DOID:811", "name": "lipodystrophy", "description": "A connective tissue disease that is characterized by marked reduction, absence, and/or the redistribution of adipose tissue.", "url": "https://disease-ontology.org/term/DOID:811", "evidence": [ { "id": "811", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:811" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" } ], "pmid": "" }, { "name": "protein processing involved in protein targeting to mitochondrion", "id": "GO:0006627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006627", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P35999-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Cys131", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Affects protein stability, but has no effect on peptidase activity.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] }, { "sequence_org": "C", "sequence_mut": "V", "comment": "Affects protein stability, but has no effect on peptidase activity.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "557", "end_pos": "557", "site_lbl": "Phe557", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "R", "comment": "Affects protein stability.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "558", "end_pos": "558", "site_lbl": "His558", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "R", "comment": "Abolishes proteolytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "559", "end_pos": "559", "site_lbl": "Glu559", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "D", "comment": "Abolishes proteolytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "561", "end_pos": "561", "site_lbl": "Gly561", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "L", "comment": "Affects protein stability.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "562", "end_pos": "562", "site_lbl": "His562", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "R", "comment": "Abolishes proteolytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "565", "end_pos": "565", "site_lbl": "His565", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "R", "comment": "Temperature sensitive; abolishes proteolytic activity for RIP1, but not for COX4.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "578", "end_pos": "578", "site_lbl": "Gly578", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "L", "comment": "Temperature sensitive; abolishes proteolytic activity for RIP1, but not for COX4.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "581", "end_pos": "581", "site_lbl": "Cys581", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Affects protein stability, but has no effect on peptidase activity.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] }, { "sequence_org": "C", "sequence_mut": "V", "comment": "Affects protein stability, but has no effect on peptidase activity.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "584", "end_pos": "584", "site_lbl": "Asp584", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "587", "end_pos": "587", "site_lbl": "Glu587", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "D", "comment": "Abolishes proteolytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "589", "end_pos": "589", "site_lbl": "Pro589", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "590", "end_pos": "590", "site_lbl": "Ser590", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "Y", "comment": "Affects protein stability.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] }, { "uniprot_canonical_ac": "P35999-1", "start_pos": "594", "end_pos": "594", "site_lbl": "Glu594", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "D", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P35999", "url": "https://www.uniprot.org/uniprotkb/P35999" }, { "database": "PubMed", "id": "8831696", "url": "https://glygen.org/publication/PubMed/8831696" } ] } ] } ], "record_id": "P35999-1" }, { "uniprot_canonical_ac": "P36005-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 433, "chemical_mass": 49633.0, "gene_names": "KDX1;KDX1;MLP1;YKL615", "protein_name": "Serine/threonine-protein kinase KDX1", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" }, { "name": "fungal-type cell wall biogenesis", "id": "GO:0009272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009272", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" }, { "name": "intracellular signaling cassette", "id": "GO:0141124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141124", "evidence": [ { "database": "UniProtKB", "id": "P36005", "url": "https://www.uniprot.org/uniprotkb/P36005" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36005-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Ser371", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36005", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36005" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001644", "url": "https://www.yeastgenome.org/locus/S000001644" } ] } ] }, { "uniprot_canonical_ac": "P36005-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36005", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36005" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P36005-1", "start_pos": "428", "end_pos": "428", "site_lbl": "Ser428", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36005", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36005" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] } ], "record_id": "P36005-1" }, { "uniprot_canonical_ac": "P36006-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1272, "chemical_mass": 142451.0, "gene_names": "MYO3;MYO3", "protein_name": "Myosin-3", "disease": [ { "disease_id": "DOID:0111131", "name": "focal segmental glomerulosclerosis 6", "description": "A focal segmental glomerulosclerosis that has_material_basis_in an autosomal recessive mutation of the MYO1E gene on chromosome 15q22.2.", "url": "https://disease-ontology.org/term/DOID:0111131", "evidence": [ { "id": "0111131", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111131" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cell tip", "id": "GO:0051286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051286", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "myosin binding", "id": "GO:0017022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017022", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "response to osmotic stress", "id": "GO:0006970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006970", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "positive regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:2000601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000601", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "actin cortical patch localization", "id": "GO:0051666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051666", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "bipolar cellular bud site selection", "id": "GO:0007121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007121", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36006-1", "start_pos": "1227", "end_pos": "1227", "site_lbl": "Thr1227", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1227, "start_aa": "Thr", "end_pos": 1227, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1227", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "920", "end_pos": "920", "site_lbl": "Thr920", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 920, "start_aa": "Thr", "end_pos": 920, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr920", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "1136", "end_pos": "1136", "site_lbl": "Ser1136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001612", "url": "https://www.yeastgenome.org/locus/S000001612" }, { "database": "iPTMnet", "id": "P36006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36006" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "1138", "end_pos": "1138", "site_lbl": "Ser1138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001612", "url": "https://www.yeastgenome.org/locus/S000001612" }, { "database": "iPTMnet", "id": "P36006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36006" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "1178", "end_pos": "1178", "site_lbl": "Thr1178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001612", "url": "https://www.yeastgenome.org/locus/S000001612" }, { "database": "iPTMnet", "id": "P36006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36006" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "1257", "end_pos": "1257", "site_lbl": "Ser1257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001612", "url": "https://www.yeastgenome.org/locus/S000001612" }, { "database": "iPTMnet", "id": "P36006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36006" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "357", "end_pos": "357", "site_lbl": "Ser357", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "9388196", "url": "https://glygen.org/publication/PubMed/9388196" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36006" }, { "database": "SGD", "id": "S000001612", "url": "https://www.yeastgenome.org/locus/S000001612" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" }, { "database": "PubMed", "id": "9388196", "url": "https://glygen.org/publication/PubMed/9388196" }, { "database": "PubMed", "id": "10648569", "url": "https://glygen.org/publication/PubMed/10648569" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Has a constitutive higher activity in actin assembly.", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" }, { "database": "PubMed", "id": "9388196", "url": "https://glygen.org/publication/PubMed/9388196" }, { "database": "PubMed", "id": "10648569", "url": "https://glygen.org/publication/PubMed/10648569" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Tyr359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001612", "url": "https://www.yeastgenome.org/locus/S000001612" }, { "database": "iPTMnet", "id": "P36006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36006" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Thr369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001612", "url": "https://www.yeastgenome.org/locus/S000001612" }, { "database": "iPTMnet", "id": "P36006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36006" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001612", "url": "https://www.yeastgenome.org/locus/S000001612" }, { "database": "iPTMnet", "id": "P36006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36006" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "777", "end_pos": "777", "site_lbl": "Ser777", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001612", "url": "https://www.yeastgenome.org/locus/S000001612" }, { "database": "iPTMnet", "id": "P36006", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36006" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "1158", "end_pos": "1158", "site_lbl": "Trp1158", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "S", "comment": "Abolishes interaction with LAS17 and causes severe mislocalization of the protein.", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" }, { "database": "PubMed", "id": "10648568", "url": "https://glygen.org/publication/PubMed/10648568" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "1272", "end_pos": "1272", "site_lbl": "Trp1272", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "", "comment": "Abolishes interaction with ARC40.", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" }, { "database": "PubMed", "id": "10648568", "url": "https://glygen.org/publication/PubMed/10648568" } ] } ] }, { "uniprot_canonical_ac": "P36006-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Gly132", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P36006", "url": "https://www.uniprot.org/uniprotkb/P36006" }, { "database": "PubMed", "id": "10648569", "url": "https://glygen.org/publication/PubMed/10648569" } ] } ] } ], "record_id": "P36006-1" }, { "uniprot_canonical_ac": "P36007-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36007", "url": "https://www.uniprot.org/uniprotkb/P36007" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 326, "chemical_mass": 34899.0, "gene_names": "SRY1;SRY1", "protein_name": "L-threo-3-hydroxyaspartate ammonia-lyase", "disease": [ { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "biological_process": [ { "name": "modified amino acid catabolic process", "id": "GO:0042219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042219", "evidence": [ { "database": "UniProtKB", "id": "P36007", "url": "https://www.uniprot.org/uniprotkb/P36007" } ], "pmid": "" }, { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "P36007", "url": "https://www.uniprot.org/uniprotkb/P36007" } ], "pmid": "" } ], "molecular_function": [ { "name": "D-serine ammonia-lyase activity", "id": "GO:0008721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008721", "evidence": [ { "database": "UniProtKB", "id": "P36007", "url": "https://www.uniprot.org/uniprotkb/P36007" } ], "pmid": "" }, { "name": "serine racemase activity", "id": "GO:0030378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030378", "evidence": [ { "database": "UniProtKB", "id": "P36007", "url": "https://www.uniprot.org/uniprotkb/P36007" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P36007", "url": "https://www.uniprot.org/uniprotkb/P36007" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P36007", "url": "https://www.uniprot.org/uniprotkb/P36007" } ], "pmid": "" }, { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "P36007", "url": "https://www.uniprot.org/uniprotkb/P36007" } ], "pmid": "" }, { "name": "L-serine ammonia-lyase activity", "id": "GO:0003941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003941", "evidence": [ { "database": "UniProtKB", "id": "P36007", "url": "https://www.uniprot.org/uniprotkb/P36007" } ], "pmid": "" }, { "name": "threo-3-hydroxyaspartate ammonia-lyase activity", "id": "GO:0030848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030848", "evidence": [ { "database": "UniProtKB", "id": "P36007", "url": "https://www.uniprot.org/uniprotkb/P36007" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36007-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001701", "url": "https://www.yeastgenome.org/locus/S000001701" }, { "database": "iPTMnet", "id": "P36007", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36007" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P36007-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001701", "url": "https://www.yeastgenome.org/locus/S000001701" }, { "database": "iPTMnet", "id": "P36007", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36007" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36007-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Thr225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001701", "url": "https://www.yeastgenome.org/locus/S000001701" }, { "database": "iPTMnet", "id": "P36007", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36007" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36007-1" }, { "uniprot_canonical_ac": "P36009-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 735, "chemical_mass": 82713.0, "gene_names": "DHR2;DHR2;YKL408", "protein_name": "Probable ATP-dependent RNA helicase DHR2", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "P36009", "url": "https://www.uniprot.org/uniprotkb/P36009" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36009-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001561", "url": "https://www.yeastgenome.org/locus/S000001561" }, { "database": "iPTMnet", "id": "P36009", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36009" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36009-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001561", "url": "https://www.yeastgenome.org/locus/S000001561" }, { "database": "iPTMnet", "id": "P36009", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36009" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36009-1" }, { "uniprot_canonical_ac": "P36012-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 229, "chemical_mass": 26841.0, "gene_names": "CSE4;CSE4;CSL2;YKL262", "protein_name": "Histone H3-like centromeric protein CSE4", "disease": [ { "disease_id": "DOID:12336", "name": "male infertility", "description": "", "url": "https://disease-ontology.org/term/DOID:12336", "evidence": [ { "id": "12336", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12336" } ], "weight": 0.0 }, { "disease_id": "DOID:14228", "name": "oligospermia", "description": "A male fertility issue defined as a low sperm concentration in the ejaculate.", "url": "https://disease-ontology.org/term/DOID:14228", "evidence": [ { "id": "14228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14228" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:417", "name": "autoimmune disease", "description": "An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.", "url": "https://disease-ontology.org/term/DOID:417", "evidence": [ { "id": "417", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:417" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "biological_process": [ { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "protein localization to CENP-A containing chromatin", "id": "GO:0061644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061644", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "2-micrometer plasmid partitioning", "id": "GO:0030543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030543", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "condensed chromosome, centromeric region", "id": "GO:0000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000779", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "CENP-A containing nucleosome", "id": "GO:0043505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043505", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "2-micrometer circle DNA", "id": "GO:0005729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005729", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "centromeric DNA binding", "id": "GO:0019237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019237", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "nucleosomal DNA binding", "id": "GO:0031492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031492", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36012-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "23637466", "url": "https://glygen.org/publication/PubMed/23637466" }, { "database": "SGD", "id": "S000001532", "url": "https://www.yeastgenome.org/locus/S000001532" }, { "database": "PubMed", "id": "30726152", "url": "https://glygen.org/publication/PubMed/30726152" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Tyr106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "23637466", "url": "https://glygen.org/publication/PubMed/23637466" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001532", "url": "https://www.yeastgenome.org/locus/S000001532" }, { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "30726152", "url": "https://glygen.org/publication/PubMed/30726152" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "23637466", "url": "https://glygen.org/publication/PubMed/23637466" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "23637466", "url": "https://glygen.org/publication/PubMed/23637466" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001532", "url": "https://www.yeastgenome.org/locus/S000001532" }, { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "30726152", "url": "https://glygen.org/publication/PubMed/30726152" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Ser154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001532", "url": "https://www.yeastgenome.org/locus/S000001532" }, { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "30726152", "url": "https://glygen.org/publication/PubMed/30726152" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001532", "url": "https://www.yeastgenome.org/locus/S000001532" }, { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "30726152", "url": "https://glygen.org/publication/PubMed/30726152" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Ser17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001532", "url": "https://www.yeastgenome.org/locus/S000001532" }, { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "30726152", "url": "https://glygen.org/publication/PubMed/30726152" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "23637466", "url": "https://glygen.org/publication/PubMed/23637466" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "23637466", "url": "https://glygen.org/publication/PubMed/23637466" }, { "database": "PubMed", "id": "29272409", "url": "https://glygen.org/publication/PubMed/29272409" }, { "database": "SGD", "id": "S000001532", "url": "https://www.yeastgenome.org/locus/S000001532" }, { "database": "PubMed", "id": "30726152", "url": "https://glygen.org/publication/PubMed/30726152" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "23637466", "url": "https://glygen.org/publication/PubMed/23637466" }, { "database": "SGD", "id": "S000001532", "url": "https://www.yeastgenome.org/locus/S000001532" }, { "database": "PubMed", "id": "30726152", "url": "https://glygen.org/publication/PubMed/30726152" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001532", "url": "https://www.yeastgenome.org/locus/S000001532" }, { "database": "iPTMnet", "id": "P36012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36012" }, { "database": "PubMed", "id": "30726152", "url": "https://glygen.org/publication/PubMed/30726152" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Leu176", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "In CSE4-102; impairs nuclear division by disrupting the core centromere structure; when associated with T-218.", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" }, { "database": "PubMed", "id": "10891506", "url": "https://glygen.org/publication/PubMed/10891506" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Leu194", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "Q", "comment": "In CSE4-111; impairs nuclear division by disrupting the core centromere structure.", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" }, { "database": "PubMed", "id": "10891506", "url": "https://glygen.org/publication/PubMed/10891506" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Leu197", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "In CSE4-110; impairs nuclear division by disrupting the core centromere structure.", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" }, { "database": "PubMed", "id": "10891506", "url": "https://glygen.org/publication/PubMed/10891506" } ] } ] }, { "uniprot_canonical_ac": "P36012-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Met218", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "T", "comment": "In CSE4-102; impairs nuclear division by disrupting the core centromere structure; when associated with S-176.", "evidence": [ { "database": "UniProtKB", "id": "P36012", "url": "https://www.uniprot.org/uniprotkb/P36012" }, { "database": "PubMed", "id": "10891506", "url": "https://glygen.org/publication/PubMed/10891506" } ] } ] } ], "record_id": "P36012-1" }, { "uniprot_canonical_ac": "P36013-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36013", "url": "https://www.uniprot.org/uniprotkb/P36013" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 669, "chemical_mass": 74376.0, "gene_names": "MAE1;MAE1", "protein_name": "NAD-dependent malic enzyme, mitochondrial", "disease": [], "molecular_function": [ { "name": "oxaloacetate decarboxylase activity", "id": "GO:0008948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008948", "evidence": [ { "database": "UniProtKB", "id": "P36013", "url": "https://www.uniprot.org/uniprotkb/P36013" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P36013", "url": "https://www.uniprot.org/uniprotkb/P36013" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "P36013", "url": "https://www.uniprot.org/uniprotkb/P36013" } ], "pmid": "" }, { "name": "malate dehydrogenase (decarboxylating) (NAD+) activity", "id": "GO:0004471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004471", "evidence": [ { "database": "UniProtKB", "id": "P36013", "url": "https://www.uniprot.org/uniprotkb/P36013" } ], "pmid": "" }, { "name": "malic enzyme activity", "id": "GO:0004470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004470", "evidence": [ { "database": "UniProtKB", "id": "P36013", "url": "https://www.uniprot.org/uniprotkb/P36013" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36013", "url": "https://www.uniprot.org/uniprotkb/P36013" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P36013", "url": "https://www.uniprot.org/uniprotkb/P36013" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "P36013", "url": "https://www.uniprot.org/uniprotkb/P36013" } ], "pmid": "" }, { "name": "malate metabolic process", "id": "GO:0006108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006108", "evidence": [ { "database": "UniProtKB", "id": "P36013", "url": "https://www.uniprot.org/uniprotkb/P36013" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36013-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Ser300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001512", "url": "https://www.yeastgenome.org/locus/S000001512" }, { "database": "iPTMnet", "id": "P36013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36013" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36013-1" }, { "uniprot_canonical_ac": "P36014-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36014", "url": "https://www.uniprot.org/uniprotkb/P36014" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 167, "chemical_mass": 19485.0, "gene_names": "GPX1;GPX1", "protein_name": "Glutathione peroxidase-like peroxiredoxin 1", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0112298", "name": "spondylometaphyseal dysplasia Sedaghatian type", "description": "A spondylometaphyseal dysplasia characterized by neonatal lethality, severe metaphyseal chondrodysplasia with mild limb shortening, platyspondyly, delayed epiphyseal ossification, irregular iliac crests, pulmonary hemorrhage, severe hypotonia and cardiorespiratory problems that has_material_basis_in homozygous or compound heterozygous mutation in the GPX4 gene on chromosome 19p13.3.", "url": "https://disease-ontology.org/term/DOID:0112298", "evidence": [ { "id": "0112298", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112298" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P36014", "url": "https://www.uniprot.org/uniprotkb/P36014" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "P36014", "url": "https://www.uniprot.org/uniprotkb/P36014" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36014", "url": "https://www.uniprot.org/uniprotkb/P36014" } ], "pmid": "" } ], "biological_process": [ { "name": "peroxisome organization", "id": "GO:0007031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007031", "evidence": [ { "database": "UniProtKB", "id": "P36014", "url": "https://www.uniprot.org/uniprotkb/P36014" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P36014", "url": "https://www.uniprot.org/uniprotkb/P36014" } ], "pmid": "" } ], "molecular_function": [ { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "P36014", "url": "https://www.uniprot.org/uniprotkb/P36014" } ], "pmid": "" }, { "name": "phospholipid-hydroperoxide glutathione peroxidase activity", "id": "GO:0047066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047066", "evidence": [ { "database": "UniProtKB", "id": "P36014", "url": "https://www.uniprot.org/uniprotkb/P36014" } ], "pmid": "" }, { "name": "thioredoxin-dependent peroxiredoxin activity", "id": "GO:0140824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140824", "evidence": [ { "database": "UniProtKB", "id": "P36014", "url": "https://www.uniprot.org/uniprotkb/P36014" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36014-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Cys36", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Prevents oxidation of the protein.", "evidence": [ { "database": "UniProtKB", "id": "P36014", "url": "https://www.uniprot.org/uniprotkb/P36014" }, { "database": "PubMed", "id": "20572871", "url": "https://glygen.org/publication/PubMed/20572871" } ] } ] } ], "record_id": "P36014-1" }, { "uniprot_canonical_ac": "P36015-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 200, "chemical_mass": 22707.0, "gene_names": "YKT6;YKT6", "protein_name": "Synaptobrevin homolog YKT6", "disease": [ { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 } ], "biological_process": [ { "name": "Golgi vesicle fusion to target membrane", "id": "GO:0048210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048210", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "vacuole fusion, non-autophagic", "id": "GO:0042144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042144", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "vesicle fusion with Golgi apparatus", "id": "GO:0048280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048280", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "autophagosome-lysosome fusion", "id": "GO:0061909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061909", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "amphisome-lysosome fusion", "id": "GO:0061911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061911", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi cis cisterna membrane", "id": "GO:1990674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990674", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "cis-Golgi network membrane", "id": "GO:0033106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033106", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" }, { "name": "palmitoyltransferase activity", "id": "GO:0016409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016409", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36015-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Thr151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36015" }, { "database": "PubMed", "id": "33025734", "url": "https://glygen.org/publication/PubMed/33025734" }, { "database": "SGD", "id": "S000001679", "url": "https://www.yeastgenome.org/locus/S000001679" } ] } ] }, { "uniprot_canonical_ac": "P36015-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Thr158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36015", "url": "https://www.uniprot.org/uniprotkb/P36015" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36015" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "33025734", "url": "https://glygen.org/publication/PubMed/33025734" }, { "database": "SGD", "id": "S000001679", "url": "https://www.yeastgenome.org/locus/S000001679" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36015-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36015" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001679", "url": "https://www.yeastgenome.org/locus/S000001679" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36015-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Ser178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36015" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001679", "url": "https://www.yeastgenome.org/locus/S000001679" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36015-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Thr180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36015" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001679", "url": "https://www.yeastgenome.org/locus/S000001679" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36015-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36015" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "33025734", "url": "https://glygen.org/publication/PubMed/33025734" }, { "database": "SGD", "id": "S000001679", "url": "https://www.yeastgenome.org/locus/S000001679" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33274589", "url": "https://glygen.org/publication/PubMed/33274589" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P36015-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36015" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "33025734", "url": "https://glygen.org/publication/PubMed/33025734" }, { "database": "SGD", "id": "S000001679", "url": "https://www.yeastgenome.org/locus/S000001679" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33274589", "url": "https://glygen.org/publication/PubMed/33274589" } ] } ] }, { "uniprot_canonical_ac": "P36015-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001679", "url": "https://www.yeastgenome.org/locus/S000001679" }, { "database": "iPTMnet", "id": "P36015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P36015-1" }, { "uniprot_canonical_ac": "P36016-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 881, "chemical_mass": 99572.0, "gene_names": "LHS1;CER1;LHS1;SSI1;YKL355", "protein_name": "Heat shock protein 70 homolog LHS1", "disease": [ { "disease_id": "DOID:0111974", "name": "immunodeficiency 59", "description": "A B cell and dendritic cell deficiency characterized by granulocytopenia, B-cell and dentritic cell deficiency, recurrent septic infections of the respiratory tract, skin, and mucous membranes, and stress-induced hypoglycemia that has_material_basis_in homozygous or compound heterozygous mutation in the HYOU1 gene on chromosome 11q23.3.", "url": "https://disease-ontology.org/term/DOID:0111974", "evidence": [ { "id": "0111974", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111974" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum chaperone complex", "id": "GO:0034663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034663", "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" } ], "pmid": "" }, { "name": "adenyl-nucleotide exchange factor activity", "id": "GO:0000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000774", "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" } ], "pmid": "" } ], "biological_process": [ { "name": "post-translational protein targeting to membrane, translocation", "id": "GO:0031204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031204", "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36016-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Asn128", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 128, "start_aa": "Asn", "end_pos": 128, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn128", "evidence": [ { "id": "P36016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36016-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Asn458", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 458, "start_aa": "Asn", "end_pos": 458, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn458", "evidence": [ { "id": "P36016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36016-1", "start_pos": "474", "end_pos": "474", "site_lbl": "Asn474", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 474, "start_aa": "Asn", "end_pos": 474, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn474", "evidence": [ { "id": "P36016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36016-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Asn481", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 481, "start_aa": "Asn", "end_pos": 481, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn481", "evidence": [ { "id": "P36016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36016-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Asn489", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 489, "start_aa": "Asn", "end_pos": 489, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn489", "evidence": [ { "id": "P36016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36016-1", "start_pos": "527", "end_pos": "527", "site_lbl": "Asn527", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 527, "start_aa": "Asn", "end_pos": 527, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn527", "evidence": [ { "id": "P36016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36016-1", "start_pos": "844", "end_pos": "844", "site_lbl": "Asn844", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 844, "start_aa": "Asn", "end_pos": 844, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn844", "evidence": [ { "id": "P36016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36016#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36016-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Gly239", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In allele LHS1-1; constitutive ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P36016", "url": "https://www.uniprot.org/uniprotkb/P36016" }, { "database": "PubMed", "id": "14704430", "url": "https://glygen.org/publication/PubMed/14704430" } ] } ] } ], "record_id": "P36016-1" }, { "uniprot_canonical_ac": "P36017-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 210, "chemical_mass": 23081.0, "gene_names": "VPS21;VPS12;VPS21;VPT12;YOR3154C;YPT21;YPT51", "protein_name": "Vacuolar protein sorting-associated protein 21", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 }, { "disease_id": "DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:557", "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ], "weight": 0.0 } ], "biological_process": [ { "name": "multivesicular body assembly", "id": "GO:0036258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036258", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "protein localization to endosome", "id": "GO:0036010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036010", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "vacuole inheritance", "id": "GO:0000011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000011", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36017-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36017", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36017" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005615", "url": "https://www.yeastgenome.org/locus/S000005615" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36017-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005615", "url": "https://www.yeastgenome.org/locus/S000005615" }, { "database": "iPTMnet", "id": "P36017", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36017" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36017-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36017", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36017" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005615", "url": "https://www.yeastgenome.org/locus/S000005615" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36017-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Ser209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005615", "url": "https://www.yeastgenome.org/locus/S000005615" }, { "database": "iPTMnet", "id": "P36017", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36017" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36017-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Thr6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005615", "url": "https://www.yeastgenome.org/locus/S000005615" }, { "database": "iPTMnet", "id": "P36017", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36017" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36017-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "L", "comment": "Locks VPS21 in its GDP-bound form by abolishing binding to GTP.", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" }, { "database": "PubMed", "id": "10021387", "url": "https://glygen.org/publication/PubMed/10021387" }, { "database": "PubMed", "id": "10329739", "url": "https://glygen.org/publication/PubMed/10329739" }, { "database": "PubMed", "id": "8137814", "url": "https://glygen.org/publication/PubMed/8137814" } ] }, { "sequence_org": "S", "sequence_mut": "N", "comment": "Locks VPS21 in its GDP-bound form by abolishing binding to GTP.", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" }, { "database": "PubMed", "id": "10021387", "url": "https://glygen.org/publication/PubMed/10021387" }, { "database": "PubMed", "id": "10329739", "url": "https://glygen.org/publication/PubMed/10329739" }, { "database": "PubMed", "id": "8137814", "url": "https://glygen.org/publication/PubMed/8137814" } ] } ] }, { "uniprot_canonical_ac": "P36017-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Gln66", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "L", "comment": "Abolishes GTP hydrolysis.", "evidence": [ { "database": "UniProtKB", "id": "P36017", "url": "https://www.uniprot.org/uniprotkb/P36017" }, { "database": "PubMed", "id": "10021387", "url": "https://glygen.org/publication/PubMed/10021387" } ] } ] } ], "record_id": "P36017-1" }, { "uniprot_canonical_ac": "P36018-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 234, "chemical_mass": 26132.0, "gene_names": "YPT52;YK112;YPT52", "protein_name": "GTP-binding protein YPT52", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 }, { "disease_id": "DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:557", "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ], "weight": 0.0 } ], "biological_process": [ { "name": "multivesicular body assembly", "id": "GO:0036258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036258", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "protein localization to endosome", "id": "GO:0036010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036010", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36018-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001722", "url": "https://www.yeastgenome.org/locus/S000001722" }, { "database": "iPTMnet", "id": "P36018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36018" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36018-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Thr136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001722", "url": "https://www.yeastgenome.org/locus/S000001722" }, { "database": "iPTMnet", "id": "P36018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36018" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36018-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Thr138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001722", "url": "https://www.yeastgenome.org/locus/S000001722" }, { "database": "iPTMnet", "id": "P36018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36018" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36018-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36018" }, { "database": "SGD", "id": "S000001722", "url": "https://www.yeastgenome.org/locus/S000001722" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36018-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36018", "url": "https://www.uniprot.org/uniprotkb/P36018" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36018" }, { "database": "SGD", "id": "S000001722", "url": "https://www.yeastgenome.org/locus/S000001722" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36018-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Thr178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001722", "url": "https://www.yeastgenome.org/locus/S000001722" }, { "database": "iPTMnet", "id": "P36018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36018" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36018-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001722", "url": "https://www.yeastgenome.org/locus/S000001722" }, { "database": "iPTMnet", "id": "P36018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36018" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36018-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001722", "url": "https://www.yeastgenome.org/locus/S000001722" }, { "database": "iPTMnet", "id": "P36018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36018" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36018-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Thr46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001722", "url": "https://www.yeastgenome.org/locus/S000001722" }, { "database": "iPTMnet", "id": "P36018", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36018" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] } ], "record_id": "P36018-1" }, { "uniprot_canonical_ac": "P36022-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 4092, "chemical_mass": 471348.0, "gene_names": "DYN1;DHC1;DYN1;PAC6", "protein_name": "Dynein heavy chain, cytoplasmic", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:0050557", "name": "congenital muscular dystrophy", "description": "A muscular dystrophy that is characterized by diminished muscle tone (hypotonia), progressive muscle weakness and degeneration (atrophy), abnormally fixed joints, spinal rigidity, and delays in reaching motor milestones such as sitting or standing unassisted.", "url": "https://disease-ontology.org/term/DOID:0050557", "evidence": [ { "id": "0050557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050557" } ], "weight": 0.0 }, { "disease_id": "DOID:0061144", "name": "complex cortical dysplasia with other brain malformations 13", "description": "A complex cortical dysplasia with other brain malformations characterized by global developmental delay with impaired intellectual development that has_material_basis_in heterozygous mutation in the DYNC1H1 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0061144", "evidence": [ { "id": "0061144", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061144" } ], "weight": 0.0 }, { "disease_id": "DOID:0070043", "name": "autosomal dominant intellectual developmental disorder 13", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the DYNC1H1 gene on chromosome 14q32.31.", "url": "https://disease-ontology.org/term/DOID:0070043", "evidence": [ { "id": "0070043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070043" } ], "weight": 0.0 }, { "disease_id": "DOID:0070351", "name": "spinal muscular atrophy with lower extremity predominant 1", "description": "A spinal muscular atrophy with lower extremity predominance that has_material_basis_in heterozygous mutation in the DYNC1H1 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0070351", "evidence": [ { "id": "0070351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070351" } ], "weight": 0.0 }, { "disease_id": "DOID:0080918", "name": "polymicrogyria", "description": "A brain disease that is characterized by malformation of the developing brain characterized by abnormal cortical lamination and an unusual folding pattern of the cerebral cortex such that all or part of the brain surface is taken up by an excessive number of small folds (gyri).", "url": "https://disease-ontology.org/term/DOID:0080918", "evidence": [ { "id": "0080918", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080918" } ], "weight": 0.0 }, { "disease_id": "DOID:0110175", "name": "Charcot-Marie-Tooth disease axonal type 2O", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in heterozygous mutation in the DYNC1H1 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0110175", "evidence": [ { "id": "0110175", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110175" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:863", "name": "nervous system disease", "description": "A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system.", "url": "https://disease-ontology.org/term/DOID:863", "evidence": [ { "id": "863", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:863" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "astral microtubule", "id": "GO:0000235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000235", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "spindle pole body", "id": "GO:0005816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005816", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" } ], "biological_process": [ { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "establishment of mitotic spindle localization", "id": "GO:0040001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040001", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "nuclear migration along microtubule", "id": "GO:0030473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030473", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" }, { "name": "karyogamy", "id": "GO:0000741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000741", "evidence": [ { "database": "UniProtKB", "id": "P36022", "url": "https://www.uniprot.org/uniprotkb/P36022" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36022-1", "start_pos": "1859", "end_pos": "1859", "site_lbl": "Ser1859", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "1862", "end_pos": "1862", "site_lbl": "Ser1862", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "2115", "end_pos": "2115", "site_lbl": "Tyr2115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "2117", "end_pos": "2117", "site_lbl": "Ser2117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "2321", "end_pos": "2321", "site_lbl": "Ser2321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" }, { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "2334", "end_pos": "2334", "site_lbl": "Ser2334", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" }, { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "3073", "end_pos": "3073", "site_lbl": "Thr3073", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" }, { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "3121", "end_pos": "3121", "site_lbl": "Thr3121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" }, { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "3269", "end_pos": "3269", "site_lbl": "Ser3269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" }, { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "3533", "end_pos": "3533", "site_lbl": "Thr3533", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" }, { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "3553", "end_pos": "3553", "site_lbl": "Thr3553", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" }, { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "4058", "end_pos": "4058", "site_lbl": "Ser4058", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" }, { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Ser620", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "623", "end_pos": "623", "site_lbl": "Thr623", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001762", "url": "https://www.yeastgenome.org/locus/S000001762" } ] } ] }, { "uniprot_canonical_ac": "P36022-1", "start_pos": "890", "end_pos": "890", "site_lbl": "Ser890", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36022", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36022" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] } ], "record_id": "P36022-1" }, { "uniprot_canonical_ac": "P36033-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36033", "url": "https://www.uniprot.org/uniprotkb/P36033" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 711, "chemical_mass": 80072.0, "gene_names": "FRE2;FRE2", "protein_name": "Ferric/cupric reductase transmembrane component 2", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P36033", "url": "https://www.uniprot.org/uniprotkb/P36033" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P36033", "url": "https://www.uniprot.org/uniprotkb/P36033" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P36033", "url": "https://www.uniprot.org/uniprotkb/P36033" } ], "pmid": "" }, { "name": "ferric-chelate reductase (NADPH) activity", "id": "GO:0052851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052851", "evidence": [ { "database": "UniProtKB", "id": "P36033", "url": "https://www.uniprot.org/uniprotkb/P36033" } ], "pmid": "" }, { "name": "ferric-chelate reductase activity", "id": "GO:0000293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000293", "evidence": [ { "database": "UniProtKB", "id": "P36033", "url": "https://www.uniprot.org/uniprotkb/P36033" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P36033", "url": "https://www.uniprot.org/uniprotkb/P36033" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "P36033", "url": "https://www.uniprot.org/uniprotkb/P36033" } ], "pmid": "" }, { "name": "copper ion import", "id": "GO:0015677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015677", "evidence": [ { "database": "UniProtKB", "id": "P36033", "url": "https://www.uniprot.org/uniprotkb/P36033" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "P36033", "url": "https://www.uniprot.org/uniprotkb/P36033" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36033-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Asn108", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 108, "start_aa": "Asn", "end_pos": 108, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn108", "evidence": [ { "id": "P36033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36033#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36033-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Asn120", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 120, "start_aa": "Asn", "end_pos": 120, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn120", "evidence": [ { "id": "P36033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36033#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36033-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Asn134", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 134, "start_aa": "Asn", "end_pos": 134, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn134", "evidence": [ { "id": "P36033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36033#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36033-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Asn341", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 341, "start_aa": "Asn", "end_pos": 341, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn341", "evidence": [ { "id": "P36033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36033#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36033-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Asn85", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 85, "start_aa": "Asn", "end_pos": 85, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn85", "evidence": [ { "id": "P36033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36033#ptm_processing" } ] } ] } ], "record_id": "P36033-1" }, { "uniprot_canonical_ac": "P36035-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 616, "chemical_mass": 69376.0, "gene_names": "JEN1;JEN1", "protein_name": "Carboxylic acid transporter protein homolog", "disease": [], "molecular_function": [ { "name": "sialic acid transmembrane transporter activity", "id": "GO:0015136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015136", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "pmid": "" }, { "name": "carboxylic acid transmembrane transporter activity", "id": "GO:0046943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046943", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "pmid": "" }, { "name": "selenite:proton symporter activity", "id": "GO:0097079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097079", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "pmid": "" } ], "biological_process": [ { "name": "plasma membrane lactate transport", "id": "GO:0035879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035879", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "pmid": "" }, { "name": "plasma membrane selenite transport", "id": "GO:0097080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097080", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "pmid": "" }, { "name": "plasma membrane pyruvate transport", "id": "GO:0006849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006849", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36035-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Ser11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36035-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36035-1", "start_pos": "584", "end_pos": "584", "site_lbl": "Ser584", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" } ] } ] }, { "uniprot_canonical_ac": "P36035-1", "start_pos": "597", "end_pos": "597", "site_lbl": "Ser597", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" }, { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36035-1", "start_pos": "603", "end_pos": "603", "site_lbl": "Ser603", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36035-1", "start_pos": "606", "end_pos": "606", "site_lbl": "Ser606", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36035-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36035-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36035-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36035", "url": "https://www.uniprot.org/uniprotkb/P36035" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36035-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Tyr80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" } ] } ] }, { "uniprot_canonical_ac": "P36035-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Ser81", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36035", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36035" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001700", "url": "https://www.yeastgenome.org/locus/S000001700" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36035-1" }, { "uniprot_canonical_ac": "P36041-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 632, "chemical_mass": 69762.0, "gene_names": "EAP1;EAP1", "protein_name": "Protein EAP1", "disease": [], "biological_process": [ { "name": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0000290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000290", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" } ], "pmid": "" }, { "name": "eukaryotic initiation factor 4E binding", "id": "GO:0008190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008190", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36041-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Ser316", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 316, "start_aa": "Ser", "end_pos": 316, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser316", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Ser327", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 327, "start_aa": "Ser", "end_pos": 327, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser327", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32027465", "url": "https://glygen.org/publication/PubMed/32027465" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 344, "start_aa": "Ser", "end_pos": 344, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser344", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Thr346", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 346, "start_aa": "Thr", "end_pos": 346, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr346", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Ser347", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 347, "start_aa": "Ser", "end_pos": 347, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser347", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Ser350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 350, "start_aa": "Ser", "end_pos": 350, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser350", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 359, "start_aa": "Ser", "end_pos": 359, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser359", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Ser360", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 360, "start_aa": "Ser", "end_pos": 360, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser360", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Ser363", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 363, "start_aa": "Ser", "end_pos": 363, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser363", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Ser371", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 371, "start_aa": "Ser", "end_pos": 371, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser371", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Ser376", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 376, "start_aa": "Ser", "end_pos": 376, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser376", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "378", "end_pos": "378", "site_lbl": "Ser378", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 378, "start_aa": "Ser", "end_pos": 378, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser378", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 53, "start_aa": "Ser", "end_pos": 53, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser53", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 56, "start_aa": "Ser", "end_pos": 56, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser56", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 57, "start_aa": "Ser", "end_pos": 57, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser57", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 60, "start_aa": "Ser", "end_pos": 60, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser60", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 61, "start_aa": "Ser", "end_pos": 61, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser61", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 64, "start_aa": "Ser", "end_pos": 64, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser64", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 68, "start_aa": "Ser", "end_pos": 68, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser68", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36041" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Ser227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Ser253", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Ser263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Thr268", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Ser281", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Thr315", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Thr325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Ser332", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Ser338", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Ser339", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Thr372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Ser387", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Ser389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Ser390", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "391", "end_pos": "391", "site_lbl": "Thr391", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Ser400", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Ser450", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001687", "url": "https://www.yeastgenome.org/locus/S000001687" }, { "database": "iPTMnet", "id": "P36041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36041" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Tyr109", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes interaction with eIF4E; when associated with A-114.", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" }, { "database": "PubMed", "id": "10848587", "url": "https://glygen.org/publication/PubMed/10848587" }, { "database": "PubMed", "id": "15848184", "url": "https://glygen.org/publication/PubMed/15848184" } ] } ] }, { "uniprot_canonical_ac": "P36041-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Leu114", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes interaction with eIF4E; when associated with A-109.", "evidence": [ { "database": "UniProtKB", "id": "P36041", "url": "https://www.uniprot.org/uniprotkb/P36041" }, { "database": "PubMed", "id": "15848184", "url": "https://glygen.org/publication/PubMed/15848184" } ] } ] } ], "record_id": "P36041-1" }, { "uniprot_canonical_ac": "P36047-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 338, "chemical_mass": 38887.0, "gene_names": "SDS22;EGP1;SDS22", "protein_name": "Protein phosphatase 1 regulatory subunit SDS22", "disease": [], "cellular_component": [ { "name": "protein phosphatase type 1 complex", "id": "GO:0000164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000164", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "pmid": "" }, { "name": "protein phosphatase activator activity", "id": "GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "pmid": "" }, { "name": "maintenance of protein location in nucleus", "id": "GO:0051457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051457", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36047-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001676", "url": "https://www.yeastgenome.org/locus/S000001676" }, { "database": "iPTMnet", "id": "P36047", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36047" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36047-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001676", "url": "https://www.yeastgenome.org/locus/S000001676" }, { "database": "iPTMnet", "id": "P36047", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36047" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36047-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001676", "url": "https://www.yeastgenome.org/locus/S000001676" }, { "database": "iPTMnet", "id": "P36047", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36047" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36047-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36047", "url": "https://www.uniprot.org/uniprotkb/P36047" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36047", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36047" }, { "database": "SGD", "id": "S000001676", "url": "https://www.yeastgenome.org/locus/S000001676" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36047-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001676", "url": "https://www.yeastgenome.org/locus/S000001676" }, { "database": "iPTMnet", "id": "P36047", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36047" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36047-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36047", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36047" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001676", "url": "https://www.yeastgenome.org/locus/S000001676" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36047-1" }, { "uniprot_canonical_ac": "P36048-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1008, "chemical_mass": 114041.0, "gene_names": "SNU114;GIN10;SNU114;YKL637", "protein_name": "Pre-mRNA-splicing factor SNU114", "disease": [ { "disease_id": "DOID:0080196", "name": "mandibulofacial dysostosis, Guion-Almeida type", "description": "A syndrome characterized by progressive microcephaly, micrognathia, microtia, dysplastic ears, preauricular skin tags, speech delay, significant developmental delay, midface and malar hypoplasia.", "url": "https://disease-ontology.org/term/DOID:0080196", "evidence": [ { "id": "0080196", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080196" } ], "weight": 0.0 }, { "disease_id": "DOID:10485", "name": "esophageal atresia", "description": "", "url": "https://disease-ontology.org/term/DOID:10485", "evidence": [ { "id": "10485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10485" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:2908", "name": "Treacher Collins syndrome", "description": "A syndrome that is characterized by bilateral and symmetric downslanting palpebral fissures, malar hypoplasia, micrognathia, and external ear abnormalities.", "url": "https://disease-ontology.org/term/DOID:2908", "evidence": [ { "id": "2908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2908" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "biological_process": [ { "name": "generation of catalytic spliceosome for first transesterification step", "id": "GO:0000349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000349", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "spliceosomal tri-snRNP complex assembly", "id": "GO:0000244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000244", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)", "id": "GO:0000388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000388", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "U5 snRNA binding", "id": "GO:0030623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030623", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" }, { "name": "Prp19 complex", "id": "GO:0000974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000974", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36048-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Thr104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001656", "url": "https://www.yeastgenome.org/locus/S000001656" }, { "database": "iPTMnet", "id": "P36048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36048" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36048-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Ser351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001656", "url": "https://www.yeastgenome.org/locus/S000001656" }, { "database": "iPTMnet", "id": "P36048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36048" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] } ] }, { "uniprot_canonical_ac": "P36048-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Thr83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36048" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001656", "url": "https://www.yeastgenome.org/locus/S000001656" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36048-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36048" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001656", "url": "https://www.yeastgenome.org/locus/S000001656" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36048-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Thr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36048", "url": "https://www.uniprot.org/uniprotkb/P36048" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36048" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001656", "url": "https://www.yeastgenome.org/locus/S000001656" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36048-1", "start_pos": "977", "end_pos": "977", "site_lbl": "Ser977", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001656", "url": "https://www.yeastgenome.org/locus/S000001656" }, { "database": "iPTMnet", "id": "P36048", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36048" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36048-1" }, { "uniprot_canonical_ac": "P36049-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 427, "chemical_mass": 49734.0, "gene_names": "EBP2;EBP2;YKL636", "protein_name": "rRNA-processing protein EBP2", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" } ], "pmid": "" }, { "name": "nuclear division", "id": "GO:0000280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000280", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36049-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Ser110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36049", "url": "https://www.uniprot.org/uniprotkb/P36049" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Ser297", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "333", "end_pos": "333", "site_lbl": "Thr333", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Thr398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Ser408", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Thr68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36049-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Thr97", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001655", "url": "https://www.yeastgenome.org/locus/S000001655" }, { "database": "iPTMnet", "id": "P36049", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36049" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P36049-1" }, { "uniprot_canonical_ac": "P36051-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 919, "chemical_mass": 105693.0, "gene_names": "MCD4;FSR2;MCD4;SSU21;YKL619;ZRG16", "protein_name": "GPI ethanolamine phosphate transferase 1", "disease": [ { "disease_id": "DOID:0080138", "name": "multiple congenital anomalies-hypotonia-seizures syndrome 1", "description": "A multiple congenital anomalies-hypotonia-seizures syndrome that is characterized by neonatal hypotonia, lack of psychomotor development, seizures, dysmorphic features, and variable congenital anomalies involving the cardiac, urinary, and gastrointestinal systems and has_material_basis_in homozygous mutation in the PIGN gene on chromosome 18q21.", "url": "https://disease-ontology.org/term/DOID:0080138", "evidence": [ { "id": "0080138", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080138" } ], "weight": 0.0 }, { "disease_id": "DOID:4621", "name": "holoprosencephaly", "description": "A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies.", "url": "https://disease-ontology.org/term/DOID:4621", "evidence": [ { "id": "4621", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4621" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mannose-ethanolamine phosphotransferase activity", "id": "GO:0051377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051377", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "pmid": "" } ], "biological_process": [ { "name": "ATP transport", "id": "GO:0015867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015867", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "pmid": "" }, { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36051-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Asn138", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 138, "start_aa": "Asn", "end_pos": 138, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn138", "evidence": [ { "id": "P36051", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36051#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36051-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Asn198", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 198, "start_aa": "Asn", "end_pos": 198, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn198", "evidence": [ { "id": "P36051", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36051#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36051-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Asn202", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 202, "start_aa": "Asn", "end_pos": 202, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn202", "evidence": [ { "id": "P36051", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36051#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36051-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Asn286", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "P36051", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36051#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36051-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Asn312", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 312, "start_aa": "Asn", "end_pos": 312, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn312", "evidence": [ { "id": "P36051", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36051#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36051-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Thr45", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 45, "start_aa": "Thr", "end_pos": 45, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr45", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P36051-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Asn90", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 90, "start_aa": "Asn", "end_pos": 90, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn90", "evidence": [ { "id": "P36051", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36051#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36051-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001648", "url": "https://www.yeastgenome.org/locus/S000001648" }, { "database": "iPTMnet", "id": "P36051", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36051" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P36051-1", "start_pos": "413", "end_pos": "413", "site_lbl": "Thr413", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001648", "url": "https://www.yeastgenome.org/locus/S000001648" }, { "database": "iPTMnet", "id": "P36051", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36051" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36051-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Gly227", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "In mcd4-174; defective in endoplasmic reticulum-to-Golgi transport of GPI-anchored proteins.", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" }, { "database": "PubMed", "id": "10069808", "url": "https://glygen.org/publication/PubMed/10069808" } ] } ] }, { "uniprot_canonical_ac": "P36051-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Pro302", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "Induces auxotrophy for ethanolamine.", "evidence": [ { "database": "UniProtKB", "id": "P36051", "url": "https://www.uniprot.org/uniprotkb/P36051" }, { "database": "PubMed", "id": "11470244", "url": "https://glygen.org/publication/PubMed/11470244" } ] } ] } ], "record_id": "P36051-1" }, { "uniprot_canonical_ac": "P36057-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36057", "url": "https://www.uniprot.org/uniprotkb/P36057" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 244, "chemical_mass": 26974.0, "gene_names": "SRP102;SRP102;YKL609", "protein_name": "Signal recognition particle receptor subunit beta", "disease": [], "cellular_component": [ { "name": "signal recognition particle receptor complex", "id": "GO:0005785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005785", "evidence": [ { "database": "UniProtKB", "id": "P36057", "url": "https://www.uniprot.org/uniprotkb/P36057" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P36057", "url": "https://www.uniprot.org/uniprotkb/P36057" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P36057", "url": "https://www.uniprot.org/uniprotkb/P36057" } ], "pmid": "" } ], "molecular_function": [ { "name": "signal recognition particle binding", "id": "GO:0005047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005047", "evidence": [ { "database": "UniProtKB", "id": "P36057", "url": "https://www.uniprot.org/uniprotkb/P36057" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P36057", "url": "https://www.uniprot.org/uniprotkb/P36057" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P36057", "url": "https://www.uniprot.org/uniprotkb/P36057" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "P36057", "url": "https://www.uniprot.org/uniprotkb/P36057" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition", "id": "GO:0006617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006617", "evidence": [ { "database": "UniProtKB", "id": "P36057", "url": "https://www.uniprot.org/uniprotkb/P36057" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P36057-1" }, { "uniprot_canonical_ac": "P36060-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36060", "url": "https://www.uniprot.org/uniprotkb/P36060" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 302, "chemical_mass": 34138.0, "gene_names": "MCR1;MCR1;YKL605", "protein_name": "NADH-cytochrome b5 reductase 2", "disease": [], "biological_process": [ { "name": "ergosterol biosynthetic process", "id": "GO:0006696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006696", "evidence": [ { "database": "UniProtKB", "id": "P36060", "url": "https://www.uniprot.org/uniprotkb/P36060" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P36060", "url": "https://www.uniprot.org/uniprotkb/P36060" } ], "pmid": "" } ], "molecular_function": [ { "name": "NADH dehydrogenase activity", "id": "GO:0003954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003954", "evidence": [ { "database": "UniProtKB", "id": "P36060", "url": "https://www.uniprot.org/uniprotkb/P36060" } ], "pmid": "" }, { "name": "cytochrome-b5 reductase activity, acting on NAD(P)H", "id": "GO:0004128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004128", "evidence": [ { "database": "UniProtKB", "id": "P36060", "url": "https://www.uniprot.org/uniprotkb/P36060" } ], "pmid": "" }, { "name": "cytochrome-b5 reductase activity, acting on NADH", "id": "GO:0090524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090524", "evidence": [ { "database": "UniProtKB", "id": "P36060", "url": "https://www.uniprot.org/uniprotkb/P36060" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36060", "url": "https://www.uniprot.org/uniprotkb/P36060" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P36060", "url": "https://www.uniprot.org/uniprotkb/P36060" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P36060", "url": "https://www.uniprot.org/uniprotkb/P36060" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36060-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Ser100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001633", "url": "https://www.yeastgenome.org/locus/S000001633" }, { "database": "iPTMnet", "id": "P36060", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36060" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36060-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ser273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001633", "url": "https://www.yeastgenome.org/locus/S000001633" }, { "database": "iPTMnet", "id": "P36060", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36060" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36060-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Ser278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36060", "url": "https://www.uniprot.org/uniprotkb/P36060" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36060", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36060" }, { "database": "SGD", "id": "S000001633", "url": "https://www.yeastgenome.org/locus/S000001633" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36060-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001633", "url": "https://www.yeastgenome.org/locus/S000001633" }, { "database": "iPTMnet", "id": "P36060", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36060" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36060-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001633", "url": "https://www.yeastgenome.org/locus/S000001633" }, { "database": "iPTMnet", "id": "P36060", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36060" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P36060-1" }, { "uniprot_canonical_ac": "P36068-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 246, "chemical_mass": 28251.0, "gene_names": "SHE2;SHE2", "protein_name": "SWI5-dependent HO expression protein 2", "disease": [], "molecular_function": [ { "name": "sequence-specific mRNA binding", "id": "GO:1990825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990825", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "pmid": "" }, { "name": "mating type switching", "id": "GO:0007533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007533", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36068-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Ser101", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Thr109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Thr147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Tyr148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Thr235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Thr47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Tyr65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001613", "url": "https://www.yeastgenome.org/locus/S000001613" }, { "database": "iPTMnet", "id": "P36068", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36068" }, { "database": "PubMed", "id": "36921931", "url": "https://glygen.org/publication/PubMed/36921931" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "Y", "comment": "Prevents dimerization and RNA-binding.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "15537539", "url": "https://glygen.org/publication/PubMed/15537539" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Leu130", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "Y", "comment": "Prevents tetramerization.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "19710186", "url": "https://glygen.org/publication/PubMed/19710186" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Asn36", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "S", "comment": "Prevents association with ASH1 and IST2 mRNAs and leads to their mislocalization.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "14561888", "url": "https://glygen.org/publication/PubMed/14561888" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Arg43", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Prevents association with ASH1 and mRNA and leads to its mislocalization.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "14561888", "url": "https://glygen.org/publication/PubMed/14561888" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Arg44", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Prevents association with ASH1 and mRNA and leads to its mislocalization.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "14561888", "url": "https://glygen.org/publication/PubMed/14561888" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Arg49", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "K", "comment": "Prevents association with ASH1 and mRNA and leads to its mislocalization.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "14561888", "url": "https://glygen.org/publication/PubMed/14561888" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Arg52", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Prevents association with ASH1 and mRNA and leads to its mislocalization.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "14561888", "url": "https://glygen.org/publication/PubMed/14561888" } ] }, { "sequence_org": "R", "sequence_mut": "K", "comment": "Prevents association with ASH1 and mRNA and leads to its mislocalization.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "14561888", "url": "https://glygen.org/publication/PubMed/14561888" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Arg63", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Prevents association with ASH1 and IST2 mRNAs and leads to their mislocalization.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "14561888", "url": "https://glygen.org/publication/PubMed/14561888" } ] }, { "sequence_org": "R", "sequence_mut": "K", "comment": "Prevents association with ASH1 and IST2 mRNAs and leads to their mislocalization.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "14561888", "url": "https://glygen.org/publication/PubMed/14561888" } ] } ] }, { "uniprot_canonical_ac": "P36068-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Cys68", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "Y", "comment": "Prevents dimerization and RNA-binding.", "evidence": [ { "database": "UniProtKB", "id": "P36068", "url": "https://www.uniprot.org/uniprotkb/P36068" }, { "database": "PubMed", "id": "15537539", "url": "https://glygen.org/publication/PubMed/15537539" } ] } ] } ], "record_id": "P36068-1" }, { "uniprot_canonical_ac": "P36075-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 443, "chemical_mass": 50874.0, "gene_names": "CUE2;CUE2", "protein_name": "Endonuclease CUE2", "disease": [], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, no-go decay", "id": "GO:0070966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070966", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" } ], "pmid": "" } ], "molecular_function": [ { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36075-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36075" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001573", "url": "https://www.yeastgenome.org/locus/S000001573" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36075-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36075" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001573", "url": "https://www.yeastgenome.org/locus/S000001573" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36075-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001573", "url": "https://www.yeastgenome.org/locus/S000001573" }, { "database": "iPTMnet", "id": "P36075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36075" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36075-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001573", "url": "https://www.yeastgenome.org/locus/S000001573" }, { "database": "iPTMnet", "id": "P36075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36075" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36075-1", "start_pos": "411", "end_pos": "411", "site_lbl": "Ser411", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36075" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000001573", "url": "https://www.yeastgenome.org/locus/S000001573" } ] } ] }, { "uniprot_canonical_ac": "P36075-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Trp122", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Abolished ability to act downstream of the RQT (ribosome quality control trigger) complex.", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" }, { "database": "PubMed", "id": "36583309", "url": "https://glygen.org/publication/PubMed/36583309" } ] } ] }, { "uniprot_canonical_ac": "P36075-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Arg402", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreased ability to participate to No-Go Decay (NGD) pathway in response to ribosome collision.", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" }, { "database": "PubMed", "id": "31219035", "url": "https://glygen.org/publication/PubMed/31219035" } ] }, { "sequence_org": "R", "sequence_mut": "K", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P36075", "url": "https://www.uniprot.org/uniprotkb/P36075" }, { "database": "PubMed", "id": "31219035", "url": "https://glygen.org/publication/PubMed/31219035" } ] } ] } ], "record_id": "P36075-1" }, { "uniprot_canonical_ac": "P36080-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36080", "url": "https://www.uniprot.org/uniprotkb/P36080" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 434, "chemical_mass": 50482.0, "gene_names": "RRP14;RRP14", "protein_name": "Ribosomal RNA-processing protein 14", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P36080", "url": "https://www.uniprot.org/uniprotkb/P36080" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P36080", "url": "https://www.uniprot.org/uniprotkb/P36080" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P36080", "url": "https://www.uniprot.org/uniprotkb/P36080" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P36080", "url": "https://www.uniprot.org/uniprotkb/P36080" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P36080", "url": "https://www.uniprot.org/uniprotkb/P36080" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "P36080", "url": "https://www.uniprot.org/uniprotkb/P36080" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36080-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Thr163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Ser232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36080-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Thr67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001565", "url": "https://www.yeastgenome.org/locus/S000001565" }, { "database": "iPTMnet", "id": "P36080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P36080-1" }, { "uniprot_canonical_ac": "P36081-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36081", "url": "https://www.uniprot.org/uniprotkb/P36081" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 392, "chemical_mass": 46036.0, "gene_names": "PSG1;PSG1", "protein_name": "PMA1 stabilization in the Golgi protein 1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P36081", "url": "https://www.uniprot.org/uniprotkb/P36081" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P36081", "url": "https://www.uniprot.org/uniprotkb/P36081" } ], "pmid": "" }, { "name": "Golgi lumen", "id": "GO:0005796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005796", "evidence": [ { "database": "UniProtKB", "id": "P36081", "url": "https://www.uniprot.org/uniprotkb/P36081" } ], "pmid": "" }, { "name": "COPI-coated vesicle membrane", "id": "GO:0030663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030663", "evidence": [ { "database": "UniProtKB", "id": "P36081", "url": "https://www.uniprot.org/uniprotkb/P36081" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "P36081", "url": "https://www.uniprot.org/uniprotkb/P36081" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "P36081", "url": "https://www.uniprot.org/uniprotkb/P36081" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36081-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 107, "start_aa": "Ser", "end_pos": 107, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser107", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Thr108", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 108, "start_aa": "Thr", "end_pos": 108, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr108", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 114, "start_aa": "Ser", "end_pos": 114, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser114", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 115, "start_aa": "Ser", "end_pos": 115, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser115", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Thr117", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 117, "start_aa": "Thr", "end_pos": 117, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr117", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 119, "start_aa": "Ser", "end_pos": 119, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser119", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 148, "start_aa": "Ser", "end_pos": 148, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser148", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Thr156", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 156, "start_aa": "Thr", "end_pos": 156, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr156", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 171, "start_aa": "Ser", "end_pos": 171, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser171", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Thr176", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 176, "start_aa": "Thr", "end_pos": 176, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr176", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 181, "start_aa": "Ser", "end_pos": 181, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser181", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Thr188", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 188, "start_aa": "Thr", "end_pos": 188, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr188", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Thr192", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 192, "start_aa": "Thr", "end_pos": 192, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr192", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Thr195", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 195, "start_aa": "Thr", "end_pos": 195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr195", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Thr199", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 203, "start_aa": "Ser", "end_pos": 203, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser203", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Ser215", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 215, "start_aa": "Ser", "end_pos": 215, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser215", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Thr34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Thr35", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 36, "start_aa": "Ser", "end_pos": 36, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser36", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Thr45", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 45, "start_aa": "Thr", "end_pos": 45, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr45", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 49, "start_aa": "Ser", "end_pos": 49, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser49", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Thr55", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Thr57", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Thr63", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 63, "start_aa": "Thr", "end_pos": 63, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr63", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 65, "start_aa": "Ser", "end_pos": 65, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser65", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Thr71", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Man) serine", "icn3d_view": {}, "start_pos": 80, "start_aa": "Ser", "end_pos": 80, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser80", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] }, { "uniprot_canonical_ac": "P36081-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Thr99", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_pos": 99, "start_aa": "Thr", "end_pos": 99, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr99", "evidence": [ { "id": "P36081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36081#ptm_processing" }, { "id": "26764011", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26764011" } ] } ] } ], "record_id": "P36081-1" }, { "uniprot_canonical_ac": "P36084-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 527, "chemical_mass": 60460.0, "gene_names": "MUD2;MUD2;YKL358", "protein_name": "Splicing factor MUD2", "disease": [ { "disease_id": "DOID:0060933", "name": "developmental delay, dysmorphic facies, and brain anomalies", "description": "An autosomal dominant intellectual developmental disorder characterized by global developmental delay with impaired intellectual development, speech delay, nonspecific dysmorphic facial features, hypotonia, and impaired overall growth with small head circumference that has_material_basis_in heterozygous mutation in the U2AF2 gene on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0060933", "evidence": [ { "id": "0060933", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060933" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" }, { "name": "pre-mRNA 3'-splice site binding", "id": "GO:0030628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030628", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" }, { "name": "pre-mRNA branch point binding", "id": "GO:0045131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045131", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" }, { "name": "poly-pyrimidine tract binding", "id": "GO:0008187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008187", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" }, { "name": "commitment complex", "id": "GO:0000243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000243", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" }, { "name": "U2AF complex", "id": "GO:0089701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089701", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" }, { "name": "mRNA branch site recognition", "id": "GO:0000348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000348", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36084-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36084", "url": "https://www.uniprot.org/uniprotkb/P36084" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P36084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36084" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001557", "url": "https://www.yeastgenome.org/locus/S000001557" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36084-1" }, { "uniprot_canonical_ac": "P36088-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36088", "url": "https://www.uniprot.org/uniprotkb/P36088" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 180, "chemical_mass": 19734.0, "gene_names": "YKL340", "protein_name": "Free methionine-R-sulfoxide reductase", "disease": [], "molecular_function": [ { "name": "L-methionine-(R)-S-oxide reductase activity", "id": "GO:0033745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033745", "evidence": [ { "database": "UniProtKB", "id": "P36088", "url": "https://www.uniprot.org/uniprotkb/P36088" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36088", "url": "https://www.uniprot.org/uniprotkb/P36088" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36088", "url": "https://www.uniprot.org/uniprotkb/P36088" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36088", "url": "https://www.uniprot.org/uniprotkb/P36088" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P36088", "url": "https://www.uniprot.org/uniprotkb/P36088" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36088-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Ser131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001552", "url": "https://www.yeastgenome.org/locus/S000001552" }, { "database": "iPTMnet", "id": "P36088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36088-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Cys101", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Dramatic reduction in enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P36088", "url": "https://www.uniprot.org/uniprotkb/P36088" }, { "database": "PubMed", "id": "19049972", "url": "https://glygen.org/publication/PubMed/19049972" } ] } ] }, { "uniprot_canonical_ac": "P36088-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Cys125", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Dramatic reduction in enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P36088", "url": "https://www.uniprot.org/uniprotkb/P36088" }, { "database": "PubMed", "id": "19049972", "url": "https://glygen.org/publication/PubMed/19049972" } ] } ] }, { "uniprot_canonical_ac": "P36088-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Cys91", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Dramatic reduction in enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P36088", "url": "https://www.uniprot.org/uniprotkb/P36088" }, { "database": "PubMed", "id": "19049972", "url": "https://glygen.org/publication/PubMed/19049972" } ] } ] } ], "record_id": "P36088-1" }, { "uniprot_canonical_ac": "P36094-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 363, "chemical_mass": 42271.0, "gene_names": "SPC42;SPC42;YKL255", "protein_name": "Spindle pole body component SPC42", "disease": [], "biological_process": [ { "name": "regulation of microtubule nucleation", "id": "GO:0010968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010968", "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" } ], "pmid": "" }, { "name": "spindle pole body duplication", "id": "GO:0030474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030474", "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" } ], "pmid": "" }, { "name": "intermediate layer of spindle pole body", "id": "GO:0005821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005821", "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" } ], "pmid": "" }, { "name": "central plaque of spindle pole body", "id": "GO:0005823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005823", "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36094-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Thr131", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Ser213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Ser284", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Tyr325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "326", "end_pos": "326", "site_lbl": "Ser326", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Ser329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36094", "url": "https://www.uniprot.org/uniprotkb/P36094" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Thr354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "357", "end_pos": "357", "site_lbl": "Thr357", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Thr359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "15296722", "url": "https://glygen.org/publication/PubMed/15296722" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Thr59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36094-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Thr6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001525", "url": "https://www.yeastgenome.org/locus/S000001525" }, { "database": "iPTMnet", "id": "P36094", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36094" }, { "database": "PubMed", "id": "15296722", "url": "https://glygen.org/publication/PubMed/15296722" } ] } ] } ], "record_id": "P36094-1" }, { "uniprot_canonical_ac": "P36095-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 224, "chemical_mass": 26242.0, "gene_names": "VPS24;DID3;VPL26;VPS24;YKL254", "protein_name": "Vacuolar protein-sorting-associated protein 24", "disease": [], "cellular_component": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" }, { "name": "intralumenal vesicle formation", "id": "GO:0070676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070676", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" }, { "name": "endosome transport via multivesicular body sorting pathway", "id": "GO:0032509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032509", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P36095", "url": "https://www.uniprot.org/uniprotkb/P36095" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36095-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001524", "url": "https://www.yeastgenome.org/locus/S000001524" }, { "database": "iPTMnet", "id": "P36095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36095" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36095-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Thr45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36095", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36095" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P36095-1" }, { "uniprot_canonical_ac": "P36096-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 758, "chemical_mass": 87880.0, "gene_names": "TUL1;TUL1;YKL247", "protein_name": "Transmembrane E3 ubiquitin-protein ligase 1", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" }, { "name": "Dsc E3 ubiquitin ligase complex", "id": "GO:0044695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044695", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" }, { "name": "EGAD pathway", "id": "GO:0140624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140624", "evidence": [ { "database": "UniProtKB", "id": "P36096", "url": "https://www.uniprot.org/uniprotkb/P36096" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P36096-1" }, { "uniprot_canonical_ac": "P36100-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36100", "url": "https://www.uniprot.org/uniprotkb/P36100" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 482, "chemical_mass": 54742.0, "gene_names": "TFA1;TFA1", "protein_name": "Transcription initiation factor IIE subunit alpha", "disease": [], "cellular_component": [ { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "P36100", "url": "https://www.uniprot.org/uniprotkb/P36100" } ], "pmid": "" }, { "name": "transcription factor TFIIE complex", "id": "GO:0005673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005673", "evidence": [ { "database": "UniProtKB", "id": "P36100", "url": "https://www.uniprot.org/uniprotkb/P36100" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36100", "url": "https://www.uniprot.org/uniprotkb/P36100" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36100", "url": "https://www.uniprot.org/uniprotkb/P36100" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P36100", "url": "https://www.uniprot.org/uniprotkb/P36100" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "P36100", "url": "https://www.uniprot.org/uniprotkb/P36100" } ], "pmid": "" } ], "biological_process": [ { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "P36100", "url": "https://www.uniprot.org/uniprotkb/P36100" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "P36100", "url": "https://www.uniprot.org/uniprotkb/P36100" } ], "pmid": "" }, { "name": "transcription open complex formation at RNA polymerase II promoter", "id": "GO:0001113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001113", "evidence": [ { "database": "UniProtKB", "id": "P36100", "url": "https://www.uniprot.org/uniprotkb/P36100" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36100-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Thr344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001511", "url": "https://www.yeastgenome.org/locus/S000001511" }, { "database": "iPTMnet", "id": "P36100", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36100" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36100-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Thr417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001511", "url": "https://www.yeastgenome.org/locus/S000001511" }, { "database": "iPTMnet", "id": "P36100", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36100" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36100-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Thr419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001511", "url": "https://www.yeastgenome.org/locus/S000001511" }, { "database": "iPTMnet", "id": "P36100", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36100" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36100-1", "start_pos": "422", "end_pos": "422", "site_lbl": "Thr422", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001511", "url": "https://www.yeastgenome.org/locus/S000001511" }, { "database": "iPTMnet", "id": "P36100", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36100" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36100-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Ser430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001511", "url": "https://www.yeastgenome.org/locus/S000001511" }, { "database": "iPTMnet", "id": "P36100", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36100" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36100-1" }, { "uniprot_canonical_ac": "P36104-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 329, "chemical_mass": 37122.0, "gene_names": "SWD2;CPS35;SAF37;SWD2", "protein_name": "COMPASS component SWD2", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "pmid": "" }, { "name": "sno(s)RNA 3'-end processing", "id": "GO:0031126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031126", "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription, poly(A)-coupled", "id": "GO:0030846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030846", "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "pmid": "" }, { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P36104", "url": "https://www.uniprot.org/uniprotkb/P36104" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36104-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36104" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P36104-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Thr3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36104" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P36104-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001501", "url": "https://www.yeastgenome.org/locus/S000001501" }, { "database": "iPTMnet", "id": "P36104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36104" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36104-1" }, { "uniprot_canonical_ac": "P36105-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 138, "chemical_mass": 15167.0, "gene_names": "RPL14A;RPL14A;YKL153", "protein_name": "Large ribosomal subunit protein eL14A", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "pmid": "" } ], "biological_process": [ { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "pmid": "" }, { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "P36105", "url": "https://www.uniprot.org/uniprotkb/P36105" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36105-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36105", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36105" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P36105-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Thr3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36105", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36105" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P36105-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36105", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36105" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001489", "url": "https://www.yeastgenome.org/locus/S000001489" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P36105-1" }, { "uniprot_canonical_ac": "P36107-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 401, "chemical_mass": 45193.0, "gene_names": "AUR1;AUR1", "protein_name": "Inositol phosphorylceramide synthase catalytic subunit AUR1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" } ], "pmid": "" }, { "name": "inositol phosphoceramide synthase complex", "id": "GO:0070916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070916", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" } ], "pmid": "" }, { "name": "mannosyl diphosphorylinositol ceramide metabolic process", "id": "GO:0006676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006676", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" } ], "pmid": "" }, { "name": "inositol phosphoceramide metabolic process", "id": "GO:0006673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006673", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" } ], "pmid": "" } ], "molecular_function": [ { "name": "inositol phosphoceramide synthase activity", "id": "GO:0045140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045140", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36107-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Asn132", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 132, "start_aa": "Asn", "end_pos": 132, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn132", "evidence": [ { "id": "P36107", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36107#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36107-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36107" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001487", "url": "https://www.yeastgenome.org/locus/S000001487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36107-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Ser389", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36107" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001487", "url": "https://www.yeastgenome.org/locus/S000001487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36107-1", "start_pos": "391", "end_pos": "391", "site_lbl": "Thr391", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001487", "url": "https://www.yeastgenome.org/locus/S000001487" }, { "database": "iPTMnet", "id": "P36107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36107" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36107-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Ser392", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36107" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001487", "url": "https://www.yeastgenome.org/locus/S000001487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36107-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Thr394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001487", "url": "https://www.yeastgenome.org/locus/S000001487" }, { "database": "iPTMnet", "id": "P36107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36107" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36107-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Ser395", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36107", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36107" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001487", "url": "https://www.yeastgenome.org/locus/S000001487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36107-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Leu137", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "F", "comment": "AbA resistant; when associated with Y-157.", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" }, { "database": "PubMed", "id": "8593016", "url": "https://glygen.org/publication/PubMed/8593016" } ] } ] }, { "uniprot_canonical_ac": "P36107-1", "start_pos": "157", "end_pos": "157", "site_lbl": "His157", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "AbA resistant; when associated with F-137.", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" }, { "database": "PubMed", "id": "8593016", "url": "https://glygen.org/publication/PubMed/8593016" } ] } ] }, { "uniprot_canonical_ac": "P36107-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Phe158", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "Y", "comment": "In AUR1-1; AbA resistant.", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" }, { "database": "PubMed", "id": "8668135", "url": "https://glygen.org/publication/PubMed/8668135" } ] } ] }, { "uniprot_canonical_ac": "P36107-1", "start_pos": "294", "end_pos": "294", "site_lbl": "His294", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P36107", "url": "https://www.uniprot.org/uniprotkb/P36107" }, { "database": "PubMed", "id": "10888667", "url": "https://glygen.org/publication/PubMed/10888667" } ] } ] } ], "record_id": "P36107-1" }, { "uniprot_canonical_ac": "P36108-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 232, "chemical_mass": 26291.0, "gene_names": "DID4;CHM2;DID4;GRD7;REN1;VPL2;VPS14;VPS2;VPT14", "protein_name": "DOA4-independent degradation protein 4", "disease": [ { "disease_id": "DOID:0111227", "name": "frontotemporal dementia and/or amyotrophic lateral sclerosis 7", "description": "A frontotemporal dementia and/or amyotrophic lateral sclerosis that has_material_basis_in heterozygous mutation in CHMP2B on 3p11.2.", "url": "https://disease-ontology.org/term/DOID:0111227", "evidence": [ { "id": "0111227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111227" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "pmid": "" } ], "biological_process": [ { "name": "protein retention in Golgi apparatus", "id": "GO:0045053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045053", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "pmid": "" }, { "name": "intralumenal vesicle formation", "id": "GO:0070676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070676", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "pmid": "" }, { "name": "endosome transport via multivesicular body sorting pathway", "id": "GO:0032509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032509", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36108-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001485", "url": "https://www.yeastgenome.org/locus/S000001485" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36108-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001485", "url": "https://www.yeastgenome.org/locus/S000001485" }, { "database": "iPTMnet", "id": "P36108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36108" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36108-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001485", "url": "https://www.yeastgenome.org/locus/S000001485" } ] } ] }, { "uniprot_canonical_ac": "P36108-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001485", "url": "https://www.yeastgenome.org/locus/S000001485" }, { "database": "iPTMnet", "id": "P36108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36108" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36108-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Leu221", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Abolishes interaction with VPS4.", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" }, { "database": "PubMed", "id": "17928861", "url": "https://glygen.org/publication/PubMed/17928861" } ] } ] }, { "uniprot_canonical_ac": "P36108-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Arg224", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "D", "comment": "Abolishes interaction with VPS4. Impairs sorting.", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" }, { "database": "PubMed", "id": "17928861", "url": "https://glygen.org/publication/PubMed/17928861" } ] } ] }, { "uniprot_canonical_ac": "P36108-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Leu225", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Abolishes interaction with VPS4.", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" }, { "database": "PubMed", "id": "17928861", "url": "https://glygen.org/publication/PubMed/17928861" } ] } ] }, { "uniprot_canonical_ac": "P36108-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Leu228", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Abolishes interaction with VPS4.", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" }, { "database": "PubMed", "id": "17928861", "url": "https://glygen.org/publication/PubMed/17928861" } ] } ] }, { "uniprot_canonical_ac": "P36108-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Lys229", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "D", "comment": "Abolishes interaction with VPS4.", "evidence": [ { "database": "UniProtKB", "id": "P36108", "url": "https://www.uniprot.org/uniprotkb/P36108" }, { "database": "PubMed", "id": "17928861", "url": "https://glygen.org/publication/PubMed/17928861" } ] } ] } ], "record_id": "P36108-1" }, { "uniprot_canonical_ac": "P36112-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36112", "url": "https://www.uniprot.org/uniprotkb/P36112" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 540, "chemical_mass": 61082.0, "gene_names": "MIC60;AIM28;FCJ1;FMP13;MIC60", "protein_name": "MICOS complex subunit MIC60", "disease": [], "biological_process": [ { "name": "protein import into mitochondrial intermembrane space", "id": "GO:0045041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045041", "evidence": [ { "database": "UniProtKB", "id": "P36112", "url": "https://www.uniprot.org/uniprotkb/P36112" } ], "pmid": "" }, { "name": "membrane bending", "id": "GO:0097753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097753", "evidence": [ { "database": "UniProtKB", "id": "P36112", "url": "https://www.uniprot.org/uniprotkb/P36112" } ], "pmid": "" }, { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "P36112", "url": "https://www.uniprot.org/uniprotkb/P36112" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36112", "url": "https://www.uniprot.org/uniprotkb/P36112" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P36112", "url": "https://www.uniprot.org/uniprotkb/P36112" } ], "pmid": "" }, { "name": "mitochondrial crista junction", "id": "GO:0044284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044284", "evidence": [ { "database": "UniProtKB", "id": "P36112", "url": "https://www.uniprot.org/uniprotkb/P36112" } ], "pmid": "" }, { "name": "MICOS complex", "id": "GO:0061617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061617", "evidence": [ { "database": "UniProtKB", "id": "P36112", "url": "https://www.uniprot.org/uniprotkb/P36112" } ], "pmid": "" }, { "name": "mitochondrial crista", "id": "GO:0030061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030061", "evidence": [ { "database": "UniProtKB", "id": "P36112", "url": "https://www.uniprot.org/uniprotkb/P36112" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "P36112", "url": "https://www.uniprot.org/uniprotkb/P36112" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P36112-1" }, { "uniprot_canonical_ac": "P36113-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36113", "url": "https://www.uniprot.org/uniprotkb/P36113" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 551, "chemical_mass": 63569.0, "gene_names": "HEL1;HEL1", "protein_name": "E3 ubiquitin-protein ligase HEL1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36113", "url": "https://www.uniprot.org/uniprotkb/P36113" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "P36113", "url": "https://www.uniprot.org/uniprotkb/P36113" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P36113", "url": "https://www.uniprot.org/uniprotkb/P36113" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "P36113", "url": "https://www.uniprot.org/uniprotkb/P36113" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "P36113", "url": "https://www.uniprot.org/uniprotkb/P36113" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P36113", "url": "https://www.uniprot.org/uniprotkb/P36113" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P36113", "url": "https://www.uniprot.org/uniprotkb/P36113" } ], "pmid": "" }, { "name": "histone catabolic process", "id": "GO:0036205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036205", "evidence": [ { "database": "UniProtKB", "id": "P36113", "url": "https://www.uniprot.org/uniprotkb/P36113" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36113-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001725", "url": "https://www.yeastgenome.org/locus/S000001725" }, { "database": "iPTMnet", "id": "P36113", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36113" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36113-1" }, { "uniprot_canonical_ac": "P36115-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 615, "chemical_mass": 68880.0, "gene_names": "IRS4;IRS4", "protein_name": "Increased rDNA silencing protein 4", "disease": [ { "disease_id": "DOID:0110734", "name": "neurodegeneration with brain iron accumulation", "description": "A neurodegenerative disease characterized by progressive iron accumulation in the basal ganglia and other regions of the brain, resulting in extrapyramidal movements, such as parkinsonism and dystonia.", "url": "https://disease-ontology.org/term/DOID:0110734", "evidence": [ { "id": "0110734", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110734" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" }, { "name": "rDNA heterochromatin formation", "id": "GO:0000183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000183", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36115-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Ser132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Ser165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Thr175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Ser180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36115", "url": "https://www.uniprot.org/uniprotkb/P36115" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Thr251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Thr358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Thr362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Ser613", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "614", "end_pos": "614", "site_lbl": "Ser614", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "615", "end_pos": "615", "site_lbl": "Ser615", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36115-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001727", "url": "https://www.yeastgenome.org/locus/S000001727" }, { "database": "iPTMnet", "id": "P36115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36115" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P36115-1" }, { "uniprot_canonical_ac": "P36116-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 164, "chemical_mass": 18912.0, "gene_names": "VPS51;API3;VPS51;VPS67;WHI6", "protein_name": "Vacuolar protein sorting-associated protein 51", "disease": [], "cellular_component": [ { "name": "GARP complex", "id": "GO:0000938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000938", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of macroautophagy", "id": "GO:0016239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" }, { "name": "vesicle organization", "id": "GO:0016050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016050", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" }, { "name": "intracellular sphingolipid homeostasis", "id": "GO:0090156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090156", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" }, { "name": "regulation of cell size", "id": "GO:0008361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008361", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" }, { "name": "budding cell apical bud growth", "id": "GO:0007118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007118", "evidence": [ { "database": "UniProtKB", "id": "P36116", "url": "https://www.uniprot.org/uniprotkb/P36116" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36116-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001728", "url": "https://www.yeastgenome.org/locus/S000001728" }, { "database": "iPTMnet", "id": "P36116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36116" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36116-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Ser88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36116" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001728", "url": "https://www.yeastgenome.org/locus/S000001728" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] } ] } ], "record_id": "P36116-1" }, { "uniprot_canonical_ac": "P36117-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 915, "chemical_mass": 102540.0, "gene_names": "ALY1;ALY1;ART6", "protein_name": "Arrestin-related trafficking adapter 6", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:14525", "name": "Reye syndrome", "description": "A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.", "url": "https://disease-ontology.org/term/DOID:14525", "evidence": [ { "id": "14525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14525" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of ubiquitin-dependent endocytosis", "id": "GO:2000397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000397", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "pmid": "" }, { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "pmid": "" }, { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36117-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Thr250", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Tyr178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36117", "url": "https://www.uniprot.org/uniprotkb/P36117" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Ser252", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Ser569", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "573", "end_pos": "573", "site_lbl": "Ser573", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Ser585", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Ser596", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "644", "end_pos": "644", "site_lbl": "Ser644", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "653", "end_pos": "653", "site_lbl": "Tyr653", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "657", "end_pos": "657", "site_lbl": "Ser657", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "659", "end_pos": "659", "site_lbl": "Ser659", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "685", "end_pos": "685", "site_lbl": "Ser685", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "767", "end_pos": "767", "site_lbl": "Thr767", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "786", "end_pos": "786", "site_lbl": "Ser786", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "813", "end_pos": "813", "site_lbl": "Ser813", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "814", "end_pos": "814", "site_lbl": "Ser814", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36117-1", "start_pos": "824", "end_pos": "824", "site_lbl": "Ser824", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001729", "url": "https://www.yeastgenome.org/locus/S000001729" }, { "database": "iPTMnet", "id": "P36117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30610170", "url": "https://glygen.org/publication/PubMed/30610170" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36117-1" }, { "uniprot_canonical_ac": "P36119-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 530, "chemical_mass": 60799.0, "gene_names": "RQT4;RQT4", "protein_name": "RQC trigger complex subunit RQT4", "disease": [], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" }, { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" }, { "name": "ribosome-associated ubiquitin-dependent protein catabolic process", "id": "GO:1990116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990116", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" }, { "name": "RQC-trigger complex", "id": "GO:0180022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180022", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36119-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Thr100", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 100, "start_aa": "Thr", "end_pos": 100, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr100", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36119", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36119" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Thr264", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 264, "start_aa": "Thr", "end_pos": 264, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr264", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36119", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36119" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 265, "start_aa": "Ser", "end_pos": 265, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser265", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36119", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36119" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Ser96", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 96, "start_aa": "Ser", "end_pos": 96, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser96", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P36119", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36119" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Ser240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Ser241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Ser426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Ser431", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Ser434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Thr455", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "457", "end_pos": "457", "site_lbl": "Ser457", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36119", "url": "https://www.uniprot.org/uniprotkb/P36119" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36119-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Ser487", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001731", "url": "https://www.yeastgenome.org/locus/S000001731" }, { "database": "iPTMnet", "id": "P36119", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36119" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36119-1" }, { "uniprot_canonical_ac": "P36126-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1683, "chemical_mass": 195204.0, "gene_names": "SPO14;PLD1;SPO14", "protein_name": "Phospholipase D1", "disease": [ { "disease_id": "DOID:0080633", "name": "developmental cardiac valvular defect", "description": "A physical disorder that has_material_basis_in homozygous or compound heterozygous mutation in the PLD1 gene on chromosome 3q26.", "url": "https://disease-ontology.org/term/DOID:0080633", "evidence": [ { "id": "0080633", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080633" } ], "weight": 0.0 }, { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phospholipase D activity", "id": "GO:0004630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004630", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidic acid biosynthetic process", "id": "GO:0006654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006654", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" }, { "name": "phospholipid catabolic process", "id": "GO:0009395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009395", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" }, { "name": "cell morphogenesis involved in conjugation with cellular fusion", "id": "GO:0000753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000753", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" }, { "name": "ascospore-type prospore assembly", "id": "GO:0031321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031321", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36126-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Thr181", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 181, "start_aa": "Thr", "end_pos": 181, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr181", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Thr10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1239", "end_pos": "1239", "site_lbl": "Ser1239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1244", "end_pos": "1244", "site_lbl": "Ser1244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1268", "end_pos": "1268", "site_lbl": "Ser1268", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1437", "end_pos": "1437", "site_lbl": "Ser1437", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1439", "end_pos": "1439", "site_lbl": "Ser1439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1442", "end_pos": "1442", "site_lbl": "Ser1442", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1443", "end_pos": "1443", "site_lbl": "Thr1443", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1447", "end_pos": "1447", "site_lbl": "Ser1447", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1449", "end_pos": "1449", "site_lbl": "Ser1449", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Ser145", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1461", "end_pos": "1461", "site_lbl": "Ser1461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "1462", "end_pos": "1462", "site_lbl": "Thr1462", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Thr263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Ser281", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Ser286", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "21954159", "url": "https://glygen.org/publication/PubMed/21954159" }, { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "655", "end_pos": "655", "site_lbl": "Ser655", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Thr6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "832", "end_pos": "832", "site_lbl": "Ser832", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36126", "url": "https://www.uniprot.org/uniprotkb/P36126" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36126-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001739", "url": "https://www.yeastgenome.org/locus/S000001739" }, { "database": "iPTMnet", "id": "P36126", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36126" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36126-1" }, { "uniprot_canonical_ac": "P36130-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 643, "chemical_mass": 72832.0, "gene_names": "CAF4;CAF4", "protein_name": "CCR4-associated factor 4", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" } ], "pmid": "" }, { "name": "peroxisome fission", "id": "GO:0016559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016559", "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36130-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Thr134", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001744", "url": "https://www.yeastgenome.org/locus/S000001744" }, { "database": "iPTMnet", "id": "P36130", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36130" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36130-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001744", "url": "https://www.yeastgenome.org/locus/S000001744" }, { "database": "iPTMnet", "id": "P36130", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36130" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36130-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001744", "url": "https://www.yeastgenome.org/locus/S000001744" }, { "database": "iPTMnet", "id": "P36130", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36130" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36130-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Ser243", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001744", "url": "https://www.yeastgenome.org/locus/S000001744" }, { "database": "iPTMnet", "id": "P36130", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36130" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36130-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Ser403", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36130", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36130" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001744", "url": "https://www.yeastgenome.org/locus/S000001744" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36130-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001744", "url": "https://www.yeastgenome.org/locus/S000001744" }, { "database": "iPTMnet", "id": "P36130", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36130" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36130-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Leu110", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes interaction with FIS1.", "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" }, { "database": "PubMed", "id": "17998537", "url": "https://glygen.org/publication/PubMed/17998537" } ] } ] }, { "uniprot_canonical_ac": "P36130-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Phe111", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Abolishes interaction with FIS1.", "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" }, { "database": "PubMed", "id": "17998537", "url": "https://glygen.org/publication/PubMed/17998537" } ] } ] }, { "uniprot_canonical_ac": "P36130-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Phe114", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Abolishes interaction with FIS1.", "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" }, { "database": "PubMed", "id": "17998537", "url": "https://glygen.org/publication/PubMed/17998537" } ] } ] }, { "uniprot_canonical_ac": "P36130-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Leu88", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes interaction with FIS1.", "evidence": [ { "database": "UniProtKB", "id": "P36130", "url": "https://www.uniprot.org/uniprotkb/P36130" }, { "database": "PubMed", "id": "17998537", "url": "https://glygen.org/publication/PubMed/17998537" } ] } ] } ], "record_id": "P36130-1" }, { "uniprot_canonical_ac": "P36131-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 295, "chemical_mass": 34078.0, "gene_names": "SPC34;SPC34", "protein_name": "DASH complex subunit SPC34", "disease": [], "biological_process": [ { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" } ], "pmid": "" }, { "name": "positive regulation of microtubule polymerization", "id": "GO:0031116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031116", "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" } ], "pmid": "" }, { "name": "positive regulation of attachment of spindle microtubules to kinetochore", "id": "GO:0051987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051987", "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" } ], "pmid": "" }, { "name": "mitotic sister chromatid biorientation", "id": "GO:1990758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990758", "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" } ], "pmid": "" }, { "name": "protein transport along microtubule to mitotic spindle pole body", "id": "GO:1990976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990976", "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" } ], "pmid": "" }, { "name": "DASH complex", "id": "GO:0042729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042729", "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36131-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Thr199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36131", "url": "https://www.uniprot.org/uniprotkb/P36131" }, { "database": "iPTMnet", "id": "P36131", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36131" }, { "database": "PubMed", "id": "12408861", "url": "https://glygen.org/publication/PubMed/12408861" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000001745", "url": "https://www.yeastgenome.org/locus/S000001745" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36131-1" }, { "uniprot_canonical_ac": "P36132-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 386, "chemical_mass": 42748.0, "gene_names": "KAE1;KAE1", "protein_name": "tRNA N6-adenosine threonylcarbamoyltransferase", "disease": [ { "disease_id": "DOID:0060879", "name": "primary hypomagnesemia", "description": "A metal metabolism disorder characterized by very low serum magnesium levels often with secondary hypocalcemia with onset typically in the first months of life.", "url": "https://disease-ontology.org/term/DOID:0060879", "evidence": [ { "id": "0060879", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060879" } ], "weight": 0.0 }, { "disease_id": "DOID:0080245", "name": "Galloway-Mowat syndrome 3", "description": "A Galloway-Mowat syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the OSGEP gene on chromosome 14q11.", "url": "https://disease-ontology.org/term/DOID:0080245", "evidence": [ { "id": "0080245", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080245" } ], "weight": 0.0 }, { "disease_id": "DOID:576", "name": "proteinuria", "description": "A kidney disease that is characterized by the presence of excess proteins in the urine.", "url": "https://disease-ontology.org/term/DOID:576", "evidence": [ { "id": "576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:576" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "nucleotidase activity", "id": "GO:0008252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008252", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "tRNA N(6)-L-threonylcarbamoyladenine synthase activity", "id": "GO:0061711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061711", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "EKC/KEOPS complex", "id": "GO:0000408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000408", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "maintenance of translational fidelity", "id": "GO:1990145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990145", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "tRNA threonylcarbamoyladenosine modification", "id": "GO:0002949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002949", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "telomere maintenance via recombination", "id": "GO:0000722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000722", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" }, { "name": "tRNA threonylcarbamoyladenosine metabolic process", "id": "GO:0070525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070525", "evidence": [ { "database": "UniProtKB", "id": "P36132", "url": "https://www.uniprot.org/uniprotkb/P36132" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36132-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Thr64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 64, "start_aa": "Thr", "end_pos": 64, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr64", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36132", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36132" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001746", "url": "https://www.yeastgenome.org/locus/S000001746" } ] } ] } ], "record_id": "P36132-1" }, { "uniprot_canonical_ac": "P36135-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 365, "chemical_mass": 36955.0, "gene_names": "UTH1;UTH1", "protein_name": "Probable secreted beta-glucosidase UTH1", "disease": [], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "pmid": "" } ], "biological_process": [ { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "pmid": "" }, { "name": "polysaccharide catabolic process", "id": "GO:0000272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000272", "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "pmid": "" }, { "name": "division septum assembly", "id": "GO:0000917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000917", "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "pmid": "" }, { "name": "fungal-type cell wall biogenesis", "id": "GO:0009272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009272", "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "pmid": "" }, { "name": "fungal-type cell wall organization", "id": "GO:0031505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031505", "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity, acting on glycosyl bonds", "id": "GO:0016798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016798", "evidence": [ { "database": "UniProtKB", "id": "P36135", "url": "https://www.uniprot.org/uniprotkb/P36135" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P36135-1" }, { "uniprot_canonical_ac": "P36136-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 271, "chemical_mass": 31022.0, "gene_names": "SHB17;SHB17", "protein_name": "Sedoheptulose 1,7-bisphosphatase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" } ], "pmid": "" }, { "name": "sedoheptulose-bisphosphatase activity", "id": "GO:0050278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050278", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" } ], "pmid": "" } ], "biological_process": [ { "name": "ribose phosphate biosynthetic process", "id": "GO:0046390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046390", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36136-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Ser207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001751", "url": "https://www.yeastgenome.org/locus/S000001751" }, { "database": "iPTMnet", "id": "P36136", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36136" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001751", "url": "https://www.yeastgenome.org/locus/S000001751" }, { "database": "iPTMnet", "id": "P36136", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36136" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001751", "url": "https://www.yeastgenome.org/locus/S000001751" }, { "database": "iPTMnet", "id": "P36136", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36136" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36136", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36136" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Thr43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001751", "url": "https://www.yeastgenome.org/locus/S000001751" }, { "database": "iPTMnet", "id": "P36136", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36136" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001751", "url": "https://www.yeastgenome.org/locus/S000001751" }, { "database": "iPTMnet", "id": "P36136", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36136" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Thr64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001751", "url": "https://www.yeastgenome.org/locus/S000001751" }, { "database": "iPTMnet", "id": "P36136", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36136" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001751", "url": "https://www.yeastgenome.org/locus/S000001751" }, { "database": "iPTMnet", "id": "P36136", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36136" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to low activity and reduced substrate affinity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Tyr102", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Impairs catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Arg12", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Trp131", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Leads to reduced substrate affinity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "13", "end_pos": "13", "site_lbl": "His13", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Impairs catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Thr16", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Impairs catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "176", "end_pos": "176", "site_lbl": "His176", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Impairs catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "178", "end_pos": "178", "site_lbl": "His178", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Leads to low activity and reduced substrate affinity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Arg181", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Leads to reduced substrate affinity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to reduced substrate affinity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Tyr24", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Leads to low activity and reduced substrate affinity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Arg69", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Leads to reduced substrate affinity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] }, { "uniprot_canonical_ac": "P36136-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Glu99", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Impairs catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P36136", "url": "https://www.uniprot.org/uniprotkb/P36136" }, { "database": "PubMed", "id": "20427268", "url": "https://glygen.org/publication/PubMed/20427268" } ] } ] } ], "record_id": "P36136-1" }, { "uniprot_canonical_ac": "P36143-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36143", "url": "https://www.uniprot.org/uniprotkb/P36143" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 616, "chemical_mass": 69724.0, "gene_names": "GLG1;GLG1", "protein_name": "Glycogenin-1", "disease": [ { "disease_id": "DOID:0050579", "name": "glycogen storage disease XV", "description": "A glycogen storage disease characterized by muscle weakness and cardiac abnormalities caused and has_material_basis_in mutation in the GYG1 gene that encodes glycogenin-1.", "url": "https://disease-ontology.org/term/DOID:0050579", "evidence": [ { "id": "0050579", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050579" } ], "weight": 0.0 }, { "disease_id": "DOID:2747", "name": "glycogen storage disease", "description": "A glycogen metabolism disorder that has_material_basis_in enzymes deficiencies necessary in the processing of glycogen synthesis or breakdown within muscles, liver, and other cell types.", "url": "https://disease-ontology.org/term/DOID:2747", "evidence": [ { "id": "2747", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2747" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "glycogenin glucosyltransferase activity", "id": "GO:0008466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008466", "evidence": [ { "database": "UniProtKB", "id": "P36143", "url": "https://www.uniprot.org/uniprotkb/P36143" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P36143", "url": "https://www.uniprot.org/uniprotkb/P36143" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36143", "url": "https://www.uniprot.org/uniprotkb/P36143" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "P36143", "url": "https://www.uniprot.org/uniprotkb/P36143" } ], "pmid": "" } ], "biological_process": [ { "name": "glycogen biosynthetic process", "id": "GO:0005978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005978", "evidence": [ { "database": "UniProtKB", "id": "P36143", "url": "https://www.uniprot.org/uniprotkb/P36143" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36143-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Tyr230", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-glucosylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "Y", "relation": "attached", "comment": "O-linked (Glc...) tyrosine;O-glucosylation", "icn3d_view": {}, "start_pos": 230, "start_aa": "Tyr", "end_pos": 230, "end_aa": "Tyr", "residue": "Tyr", "site_lbl": "Tyr230", "evidence": [ { "id": "P36143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36143#ptm_processing" } ] } ], "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Eliminates glycogen accumulation; when associated with F-598.", "evidence": [ { "database": "UniProtKB", "id": "P36143", "url": "https://www.uniprot.org/uniprotkb/P36143" }, { "database": "PubMed", "id": "8900126", "url": "https://glygen.org/publication/PubMed/8900126" } ] } ] }, { "uniprot_canonical_ac": "P36143-1", "start_pos": "598", "end_pos": "598", "site_lbl": "Tyr598", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-glucosylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "Y", "relation": "attached", "comment": "O-linked (Glc...) tyrosine;O-glucosylation", "icn3d_view": {}, "start_pos": 598, "start_aa": "Tyr", "end_pos": 598, "end_aa": "Tyr", "residue": "Tyr", "site_lbl": "Tyr598", "evidence": [ { "id": "P36143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36143#ptm_processing" } ] } ], "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Eliminates glycogen accumulation; when associated with F-230.", "evidence": [ { "database": "UniProtKB", "id": "P36143", "url": "https://www.uniprot.org/uniprotkb/P36143" }, { "database": "PubMed", "id": "8900126", "url": "https://glygen.org/publication/PubMed/8900126" } ] } ] }, { "uniprot_canonical_ac": "P36143-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Ser477", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001766", "url": "https://www.yeastgenome.org/locus/S000001766" }, { "database": "iPTMnet", "id": "P36143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36143" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36143-1" }, { "uniprot_canonical_ac": "P36146-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 502, "chemical_mass": 59351.0, "gene_names": "LAS1;LAS1", "protein_name": "Protein LAS1", "disease": [ { "disease_id": "DOID:0060814", "name": "Wilson-Turner syndrome", "description": "A syndromic X-linked intellectual disability characterized by intellectual disability, truncal obesity, gynecomastia, hypogonadism, dysmorphic facial features, and short stature that has_material_basis_in hemizygous mutation in the LAS1L gene on chromosome Xq12.", "url": "https://disease-ontology.org/term/DOID:0060814", "evidence": [ { "id": "0060814", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060814" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" }, { "name": "Las1 complex", "id": "GO:0090730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090730", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" } ], "molecular_function": [ { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" } ], "biological_process": [ { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" }, { "name": "cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000448", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "P36146", "url": "https://www.uniprot.org/uniprotkb/P36146" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36146-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36146" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001771", "url": "https://www.yeastgenome.org/locus/S000001771" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36146-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Ser244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001771", "url": "https://www.yeastgenome.org/locus/S000001771" }, { "database": "iPTMnet", "id": "P36146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36146" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P36146-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Ser245", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001771", "url": "https://www.yeastgenome.org/locus/S000001771" }, { "database": "iPTMnet", "id": "P36146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36146" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P36146-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Ser436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001771", "url": "https://www.yeastgenome.org/locus/S000001771" }, { "database": "iPTMnet", "id": "P36146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36146" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36146-1", "start_pos": "444", "end_pos": "444", "site_lbl": "Ser444", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36146" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001771", "url": "https://www.yeastgenome.org/locus/S000001771" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36146-1", "start_pos": "467", "end_pos": "467", "site_lbl": "Ser467", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001771", "url": "https://www.yeastgenome.org/locus/S000001771" }, { "database": "iPTMnet", "id": "P36146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36146" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36146-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Thr483", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001771", "url": "https://www.yeastgenome.org/locus/S000001771" }, { "database": "iPTMnet", "id": "P36146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36146" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P36146-1" }, { "uniprot_canonical_ac": "P36148-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 743, "chemical_mass": 83645.0, "gene_names": "GPT2;GAT1;GPT2", "protein_name": "Glycerol-3-phosphate O-acyltransferase 2", "disease": [], "molecular_function": [ { "name": "glycerone-phosphate O-acyltransferase activity", "id": "GO:0016287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016287", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ], "pmid": "" }, { "name": "glycerol-3-phosphate O-acyltransferase activity", "id": "GO:0004366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004366", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ], "pmid": "" }, { "name": "regulation of triglyceride metabolic process", "id": "GO:0090207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090207", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ], "pmid": "" }, { "name": "CDP-diacylglycerol biosynthetic process", "id": "GO:0016024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016024", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36148-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "631", "end_pos": "631", "site_lbl": "Ser631", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Ser632", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "636", "end_pos": "636", "site_lbl": "Ser636", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "637", "end_pos": "637", "site_lbl": "Ser637", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "642", "end_pos": "642", "site_lbl": "Ser642", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Ser647", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "649", "end_pos": "649", "site_lbl": "Ser649", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "651", "end_pos": "651", "site_lbl": "Ser651", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "654", "end_pos": "654", "site_lbl": "Ser654", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "657", "end_pos": "657", "site_lbl": "Ser657", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "660", "end_pos": "660", "site_lbl": "Ser660", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "664", "end_pos": "664", "site_lbl": "Ser664", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "31421179", "url": "https://glygen.org/publication/PubMed/31421179" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "In GPT2-3A; increases the enzyme activity of GPT2; when associated with A-668 and A-671.", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "668", "end_pos": "668", "site_lbl": "Ser668", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "31421179", "url": "https://glygen.org/publication/PubMed/31421179" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "In GPT2-3A; increases the enzyme activity of GPT2; when associated with A-664 and A-671.", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "671", "end_pos": "671", "site_lbl": "Ser671", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "31421179", "url": "https://glygen.org/publication/PubMed/31421179" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "In GPT2-3A; increases the enzyme activity of GPT2; when associated with A-664 and A-668.", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "673", "end_pos": "673", "site_lbl": "Thr673", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "688", "end_pos": "688", "site_lbl": "Ser688", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "692", "end_pos": "692", "site_lbl": "Thr692", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "693", "end_pos": "693", "site_lbl": "Ser693", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36148", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36148" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001775", "url": "https://www.yeastgenome.org/locus/S000001775" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36148-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Gly262", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In GAT1-TTA1; abolishes both GAT and DHAPAT activities.", "evidence": [ { "database": "UniProtKB", "id": "P36148", "url": "https://www.uniprot.org/uniprotkb/P36148" }, { "database": "PubMed", "id": "11544256", "url": "https://glygen.org/publication/PubMed/11544256" } ] } ] } ], "record_id": "P36148-1" }, { "uniprot_canonical_ac": "P36149-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 193, "chemical_mass": 22129.0, "gene_names": "BET3;BET3", "protein_name": "Trafficking protein particle complex subunit BET3", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "TRAPPIII protein complex", "id": "GO:1990072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990072", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "TRAPPI protein complex", "id": "GO:1990070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990070", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "cis-Golgi network membrane", "id": "GO:0033106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033106", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "TRAPP complex", "id": "GO:0030008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030008", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "TRAPPII protein complex", "id": "GO:1990071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990071", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" } ], "biological_process": [ { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36149-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001776", "url": "https://www.yeastgenome.org/locus/S000001776" }, { "database": "iPTMnet", "id": "P36149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36149-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001776", "url": "https://www.yeastgenome.org/locus/S000001776" }, { "database": "iPTMnet", "id": "P36149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36149-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Cys80", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Loss of palmitoylation.", "evidence": [ { "database": "UniProtKB", "id": "P36149", "url": "https://www.uniprot.org/uniprotkb/P36149" }, { "database": "PubMed", "id": "15692564", "url": "https://glygen.org/publication/PubMed/15692564" } ] } ] } ], "record_id": "P36149-1" }, { "uniprot_canonical_ac": "P36156-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 370, "chemical_mass": 43274.0, "gene_names": "ECM4;ECM4;GTO2", "protein_name": "Glutathione S-transferase omega-like 2", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" } ], "pmid": "" }, { "name": "glutathione dehydrogenase (ascorbate) activity", "id": "GO:0045174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045174", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" } ], "pmid": "" } ], "biological_process": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36156-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001784", "url": "https://www.yeastgenome.org/locus/S000001784" }, { "database": "iPTMnet", "id": "P36156", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36156" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36156-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001784", "url": "https://www.yeastgenome.org/locus/S000001784" }, { "database": "iPTMnet", "id": "P36156", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36156" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36156-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Ser115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001784", "url": "https://www.yeastgenome.org/locus/S000001784" }, { "database": "iPTMnet", "id": "P36156", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36156" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36156-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001784", "url": "https://www.yeastgenome.org/locus/S000001784" }, { "database": "iPTMnet", "id": "P36156", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36156" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36156-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Glu173", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "No effect on thiol transferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" }, { "database": "PubMed", "id": "16709151", "url": "https://glygen.org/publication/PubMed/16709151" } ] }, { "sequence_org": "E", "sequence_mut": "D", "comment": "No effect on thiol transferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" }, { "database": "PubMed", "id": "16709151", "url": "https://glygen.org/publication/PubMed/16709151" } ] } ] }, { "uniprot_canonical_ac": "P36156-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Ser174", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on thiol transferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" }, { "database": "PubMed", "id": "16709151", "url": "https://glygen.org/publication/PubMed/16709151" } ] } ] }, { "uniprot_canonical_ac": "P36156-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Leu246", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "No effect on thiol transferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" }, { "database": "PubMed", "id": "16709151", "url": "https://glygen.org/publication/PubMed/16709151" } ] } ] }, { "uniprot_canonical_ac": "P36156-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Gly280", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "L", "comment": "No effect on thiol transferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" }, { "database": "PubMed", "id": "16709151", "url": "https://glygen.org/publication/PubMed/16709151" } ] } ] }, { "uniprot_canonical_ac": "P36156-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Asp287", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "G", "comment": "Abolishes thiol transferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" }, { "database": "PubMed", "id": "16709151", "url": "https://glygen.org/publication/PubMed/16709151" } ] } ] }, { "uniprot_canonical_ac": "P36156-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Cys46", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Completely inactive as thiol transferase. No activity recovered against 1-chloro-2,4-dinitrobenzene (CDNB).", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" }, { "database": "PubMed", "id": "16709151", "url": "https://glygen.org/publication/PubMed/16709151" } ] }, { "sequence_org": "C", "sequence_mut": "Y", "comment": "Completely inactive as thiol transferase. No activity recovered against 1-chloro-2,4-dinitrobenzene (CDNB).", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" }, { "database": "PubMed", "id": "16709151", "url": "https://glygen.org/publication/PubMed/16709151" } ] } ] }, { "uniprot_canonical_ac": "P36156-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Arg51", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on thiol transferase activity. No effect on thiol transferase activity; when associated with D-173.", "evidence": [ { "database": "UniProtKB", "id": "P36156", "url": "https://www.uniprot.org/uniprotkb/P36156" }, { "database": "PubMed", "id": "16709151", "url": "https://glygen.org/publication/PubMed/16709151" } ] } ] } ], "record_id": "P36156-1" }, { "uniprot_canonical_ac": "P36159-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36159", "url": "https://www.uniprot.org/uniprotkb/P36159" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 838, "chemical_mass": 96816.0, "gene_names": "TRZ1;TRZ1", "protein_name": "Ribonuclease Z", "disease": [ { "disease_id": "DOID:0060536", "name": "mitochondrial complex I deficiency", "description": "A mitochondrial metabolism disease characterized by a wide range of manifestations including marked and often fatal lactic acidosis, cardiomyopathy, leukoencephalopathy, pure myopathy and hepatopathy with tubulopathy. Among the numerous clinical phenotypes observed are Leigh syndrome, Leber hereditary optic neuropathy and MELAS syndrome. It can have material basis in mutations in multiple different genes, both nuclear-encoded and mitochondrial-encoded.", "url": "https://disease-ontology.org/term/DOID:0060536", "evidence": [ { "id": "0060536", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060536" } ], "weight": 0.0 }, { "disease_id": "DOID:0111496", "name": "combined oxidative phosphorylation deficiency 17", "description": "A combined oxidative phosphorylation deficiency characterized by onset in the first years of life of severe hypertrophic cardiomyopathy that has_material_basis_in homozygous or compound heterozygous mutation in the ELAC2 gene on chromosome 17p12.", "url": "https://disease-ontology.org/term/DOID:0111496", "evidence": [ { "id": "0111496", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111496" } ], "weight": 0.0 }, { "disease_id": "DOID:0111753", "name": "infantile hypertrophic cardiomyopathy", "description": "A hypertrophic cardiomyopathy characterized by isolated hypertrophic cardiomyopathy and congestive heart failure that has_material_basis_in mutation in the overlapping mitochondrial genes MTATP6 and MTATP8.", "url": "https://disease-ontology.org/term/DOID:0111753", "evidence": [ { "id": "0111753", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111753" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36159", "url": "https://www.uniprot.org/uniprotkb/P36159" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36159", "url": "https://www.uniprot.org/uniprotkb/P36159" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36159", "url": "https://www.uniprot.org/uniprotkb/P36159" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P36159", "url": "https://www.uniprot.org/uniprotkb/P36159" } ], "pmid": "" }, { "name": "3'-tRNA processing endoribonuclease activity", "id": "GO:0042781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042781", "evidence": [ { "database": "UniProtKB", "id": "P36159", "url": "https://www.uniprot.org/uniprotkb/P36159" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA 3'-end processing", "id": "GO:0042780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042780", "evidence": [ { "database": "UniProtKB", "id": "P36159", "url": "https://www.uniprot.org/uniprotkb/P36159" } ], "pmid": "" }, { "name": "mitochondrial tRNA 3'-end processing", "id": "GO:1990180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990180", "evidence": [ { "database": "UniProtKB", "id": "P36159", "url": "https://www.uniprot.org/uniprotkb/P36159" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36159-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001787", "url": "https://www.yeastgenome.org/locus/S000001787" }, { "database": "iPTMnet", "id": "P36159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36159" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36159-1", "start_pos": "366", "end_pos": "366", "site_lbl": "Thr366", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001787", "url": "https://www.yeastgenome.org/locus/S000001787" }, { "database": "iPTMnet", "id": "P36159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36159" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36159-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001787", "url": "https://www.yeastgenome.org/locus/S000001787" }, { "database": "iPTMnet", "id": "P36159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36159" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36159-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001787", "url": "https://www.yeastgenome.org/locus/S000001787" }, { "database": "iPTMnet", "id": "P36159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36159" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36159-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Ser551", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36159" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001787", "url": "https://www.yeastgenome.org/locus/S000001787" } ] } ] }, { "uniprot_canonical_ac": "P36159-1", "start_pos": "824", "end_pos": "824", "site_lbl": "Ser824", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36159", "url": "https://www.uniprot.org/uniprotkb/P36159" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P36159", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36159" }, { "database": "SGD", "id": "S000001787", "url": "https://www.yeastgenome.org/locus/S000001787" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36159-1" }, { "uniprot_canonical_ac": "P36161-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1157, "chemical_mass": 133321.0, "gene_names": "NUP133;NUP133;RAT3;YKR402", "protein_name": "Nucleoporin NUP133", "disease": [ { "disease_id": "DOID:0060364", "name": "Galloway-Mowat syndrome 1", "description": "A Galloway-Mowat syndrome that has_material_basis_in homozygous mutation in the WDR73 gene on chromosome 15q25.", "url": "https://disease-ontology.org/term/DOID:0060364", "evidence": [ { "id": "0060364", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060364" } ], "weight": 0.0 }, { "disease_id": "DOID:0080393", "name": "nephrotic syndrome type 18", "description": "A familial nephrotic syndrome that has_material_basis_in by homozygous or compound heterozygous mutation in the NUP133 gene on chromosome 1q42.", "url": "https://disease-ontology.org/term/DOID:0080393", "evidence": [ { "id": "0080393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080393" } ], "weight": 0.0 }, { "disease_id": "DOID:0080694", "name": "Galloway-Mowat syndrome", "description": "A syndrome that is characterized by developmental delay, progressive microcephaly, cerebral and cerebellar atrophy with extrapyramidal involvement, and optic atrophy.", "url": "https://disease-ontology.org/term/DOID:0080694", "evidence": [ { "id": "0080694", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080694" } ], "weight": 0.0 } ], "biological_process": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "tRNA export from nucleus", "id": "GO:0006409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006409", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "mRNA export from nucleus in response to heat stress", "id": "GO:0031990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031990", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000973", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "telomere tethering at nuclear periphery", "id": "GO:0034398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034398", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000972", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "nuclear pore localization", "id": "GO:0051664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051664", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "silent mating-type cassette heterochromatin formation", "id": "GO:0030466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030466", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore outer ring", "id": "GO:0031080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "P36161", "url": "https://www.uniprot.org/uniprotkb/P36161" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36161-1", "start_pos": "1051", "end_pos": "1051", "site_lbl": "Ser1051", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Ser435", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "619", "end_pos": "619", "site_lbl": "Ser619", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "916", "end_pos": "916", "site_lbl": "Ser916", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36161-1", "start_pos": "918", "end_pos": "918", "site_lbl": "Ser918", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001790", "url": "https://www.yeastgenome.org/locus/S000001790" }, { "database": "iPTMnet", "id": "P36161", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36161" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36161-1" }, { "uniprot_canonical_ac": "P36162-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 133, "chemical_mass": 15072.0, "gene_names": "DAD2;DAD2;HSK1;YKR403", "protein_name": "DASH complex subunit DAD2", "disease": [], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" }, { "name": "mitotic spindle midzone", "id": "GO:1990023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990023", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" }, { "name": "DASH complex", "id": "GO:0042729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042729", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" }, { "name": "mitotic spindle pole body", "id": "GO:0044732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044732", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" } ], "biological_process": [ { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" }, { "name": "positive regulation of microtubule polymerization", "id": "GO:0031116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031116", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" }, { "name": "positive regulation of attachment of spindle microtubules to kinetochore", "id": "GO:0051987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051987", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" }, { "name": "mitotic sister chromatid biorientation", "id": "GO:1990758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990758", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" }, { "name": "protein transport along microtubule to mitotic spindle pole body", "id": "GO:1990976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990976", "evidence": [ { "database": "UniProtKB", "id": "P36162", "url": "https://www.uniprot.org/uniprotkb/P36162" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P36162-1" }, { "uniprot_canonical_ac": "P36165-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 910, "chemical_mass": 102717.0, "gene_names": "TGL4;STC1;TGL4;YKR409", "protein_name": "Triacylglycerol lipase 4", "disease": [], "molecular_function": [ { "name": "sterol ester esterase activity", "id": "GO:0004771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004771", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" } ], "pmid": "" }, { "name": "lysophosphatidic acid acyltransferase activity", "id": "GO:0042171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042171", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" } ], "pmid": "" } ], "cellular_component": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" } ], "pmid": "" } ], "biological_process": [ { "name": "triglyceride catabolic process", "id": "GO:0019433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019433", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" } ], "pmid": "" }, { "name": "triglyceride mobilization", "id": "GO:0006642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006642", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" } ], "pmid": "" }, { "name": "cell budding", "id": "GO:0007114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007114", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36165-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Ser472", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "648", "end_pos": "648", "site_lbl": "Ser648", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "673", "end_pos": "673", "site_lbl": "Thr673", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "675", "end_pos": "675", "site_lbl": "Thr675", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "19150427", "url": "https://glygen.org/publication/PubMed/19150427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "19150427", "url": "https://glygen.org/publication/PubMed/19150427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19150427", "url": "https://glygen.org/publication/PubMed/19150427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "E", "comment": "Highly stimulates TGA lipolysis.", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" }, { "database": "PubMed", "id": "19150427", "url": "https://glygen.org/publication/PubMed/19150427" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "677", "end_pos": "677", "site_lbl": "Thr677", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Ser684", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "708", "end_pos": "708", "site_lbl": "Ser708", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Ser713", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Ser715", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "721", "end_pos": "721", "site_lbl": "Tyr721", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "722", "end_pos": "722", "site_lbl": "Ser722", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "725", "end_pos": "725", "site_lbl": "Ser725", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "727", "end_pos": "727", "site_lbl": "Ser727", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "737", "end_pos": "737", "site_lbl": "Ser737", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "739", "end_pos": "739", "site_lbl": "Thr739", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "749", "end_pos": "749", "site_lbl": "Ser749", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "751", "end_pos": "751", "site_lbl": "Ser751", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "753", "end_pos": "753", "site_lbl": "Ser753", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "756", "end_pos": "756", "site_lbl": "Ser756", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "758", "end_pos": "758", "site_lbl": "Thr758", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "781", "end_pos": "781", "site_lbl": "Ser781", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "836", "end_pos": "836", "site_lbl": "Ser836", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "877", "end_pos": "877", "site_lbl": "Ser877", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "890", "end_pos": "890", "site_lbl": "Ser890", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36165", "url": "https://www.uniprot.org/uniprotkb/P36165" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19150427", "url": "https://glygen.org/publication/PubMed/19150427" }, { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "894", "end_pos": "894", "site_lbl": "Ser894", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "897", "end_pos": "897", "site_lbl": "Ser897", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "898", "end_pos": "898", "site_lbl": "Ser898", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "904", "end_pos": "904", "site_lbl": "Ser904", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P36165-1", "start_pos": "909", "end_pos": "909", "site_lbl": "Thr909", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001797", "url": "https://www.yeastgenome.org/locus/S000001797" }, { "database": "iPTMnet", "id": "P36165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36165-1" }, { "uniprot_canonical_ac": "P36170-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36170", "url": "https://www.uniprot.org/uniprotkb/P36170" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1169, "chemical_mass": 122165.0, "gene_names": "FLO10;FLO10", "protein_name": "Flocculation protein FLO10", "disease": [], "cellular_component": [ { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P36170", "url": "https://www.uniprot.org/uniprotkb/P36170" } ], "pmid": "" }, { "name": "fungal-type cell wall", "id": "GO:0009277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009277", "evidence": [ { "database": "UniProtKB", "id": "P36170", "url": "https://www.uniprot.org/uniprotkb/P36170" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "P36170", "url": "https://www.uniprot.org/uniprotkb/P36170" } ], "pmid": "" } ], "molecular_function": [ { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "P36170", "url": "https://www.uniprot.org/uniprotkb/P36170" } ], "pmid": "" } ], "biological_process": [ { "name": "flocculation", "id": "GO:0000128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000128", "evidence": [ { "database": "UniProtKB", "id": "P36170", "url": "https://www.uniprot.org/uniprotkb/P36170" } ], "pmid": "" }, { "name": "invasive growth in response to glucose limitation", "id": "GO:0001403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001403", "evidence": [ { "database": "UniProtKB", "id": "P36170", "url": "https://www.uniprot.org/uniprotkb/P36170" } ], "pmid": "" }, { "name": "filamentous growth of a population of unicellular organisms", "id": "GO:0044182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044182", "evidence": [ { "database": "UniProtKB", "id": "P36170", "url": "https://www.uniprot.org/uniprotkb/P36170" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36170-1", "start_pos": "1092", "end_pos": "1092", "site_lbl": "Asn1092", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1092, "start_aa": "Asn", "end_pos": 1092, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1092", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "1099", "end_pos": "1099", "site_lbl": "Asn1099", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1099, "start_aa": "Asn", "end_pos": 1099, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1099", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Asn122", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 122, "start_aa": "Asn", "end_pos": 122, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn122", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Asn157", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 157, "start_aa": "Asn", "end_pos": 157, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn157", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Asn279", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 279, "start_aa": "Asn", "end_pos": 279, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn279", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Asn389", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 389, "start_aa": "Asn", "end_pos": 389, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn389", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Asn452", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 452, "start_aa": "Asn", "end_pos": 452, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn452", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Asn515", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 515, "start_aa": "Asn", "end_pos": 515, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn515", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "578", "end_pos": "578", "site_lbl": "Asn578", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 578, "start_aa": "Asn", "end_pos": 578, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn578", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "656", "end_pos": "656", "site_lbl": "Asn656", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 656, "start_aa": "Asn", "end_pos": 656, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn656", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "686", "end_pos": "686", "site_lbl": "Asn686", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 686, "start_aa": "Asn", "end_pos": 686, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn686", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "856", "end_pos": "856", "site_lbl": "Thr856", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 856, "start_aa": "Thr", "end_pos": 856, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr856", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P36170-1", "start_pos": "879", "end_pos": "879", "site_lbl": "Asn879", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 879, "start_aa": "Asn", "end_pos": 879, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn879", "evidence": [ { "id": "P36170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P36170#ptm_processing" } ] } ] } ], "record_id": "P36170-1" }, { "uniprot_canonical_ac": "P36224-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 373, "chemical_mass": 43607.0, "gene_names": "JNM1;INS1;JNM1;PAC3", "protein_name": "Nuclear migration protein JNM1", "disease": [ { "disease_id": "DOID:0050890", "name": "synucleinopathy", "description": "A neurodegenerative disease that is characterized by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells.", "url": "https://disease-ontology.org/term/DOID:0050890", "evidence": [ { "id": "0050890", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050890" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "pmid": "" }, { "name": "dynactin complex", "id": "GO:0005869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005869", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36224-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004908", "url": "https://www.yeastgenome.org/locus/S000004908" }, { "database": "iPTMnet", "id": "P36224", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36224" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36224-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36224", "url": "https://www.uniprot.org/uniprotkb/P36224" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36224", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36224" }, { "database": "SGD", "id": "S000004908", "url": "https://www.yeastgenome.org/locus/S000004908" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P36224-1" }, { "uniprot_canonical_ac": "P36421-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 394, "chemical_mass": 44020.0, "gene_names": "TYS1;G7522;MGM104;TTS1;TYS1", "protein_name": "Tyrosine--tRNA ligase, cytoplasmic", "disease": [ { "disease_id": "DOID:0110199", "name": "Charcot-Marie-Tooth disease dominant intermediate C", "description": "A Charcot-Marie-Tooth disease intermediate type that has_material_basis_in heterozygous mutation in the YARS gene on chromosome 1p35.", "url": "https://disease-ontology.org/term/DOID:0110199", "evidence": [ { "id": "0110199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110199" } ], "weight": 0.0 }, { "disease_id": "DOID:070355", "name": "multisystem proteinopathy", "description": "A motor neuron disease that has_material_basis_in some inheritance and affects muscle, bone, and the nervous system.", "url": "https://disease-ontology.org/term/DOID:070355", "evidence": [ { "id": "070355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:070355" } ], "weight": 0.0 }, { "disease_id": "DOID:10595", "name": "Charcot-Marie-Tooth disease", "description": "A neuromuscular disease that is characterized by a slowly progressive degeneration of the muscles of the foot, lower leg, hand and forearm.", "url": "https://disease-ontology.org/term/DOID:10595", "evidence": [ { "id": "10595", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10595" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:870", "name": "neuropathy", "description": "A nervous system disease that is located_in nerves or nerve cells.", "url": "https://disease-ontology.org/term/DOID:870", "evidence": [ { "id": "870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:870" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "sequence-specific mRNA binding", "id": "GO:1990825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990825", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" } ], "pmid": "" }, { "name": "tyrosine-tRNA ligase activity", "id": "GO:0004831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004831", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" } ], "pmid": "" } ], "biological_process": [ { "name": "tyrosyl-tRNA aminoacylation", "id": "GO:0006437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006437", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36421-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Ser111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003417", "url": "https://www.yeastgenome.org/locus/S000003417" }, { "database": "iPTMnet", "id": "P36421", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36421" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003417", "url": "https://www.yeastgenome.org/locus/S000003417" }, { "database": "iPTMnet", "id": "P36421", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36421" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36421", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36421" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003417", "url": "https://www.yeastgenome.org/locus/S000003417" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36421", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36421" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Ser318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003417", "url": "https://www.yeastgenome.org/locus/S000003417" }, { "database": "iPTMnet", "id": "P36421", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36421" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Ser351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003417", "url": "https://www.yeastgenome.org/locus/S000003417" }, { "database": "iPTMnet", "id": "P36421", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36421" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Thr359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P36421", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36421" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003417", "url": "https://www.yeastgenome.org/locus/S000003417" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Ser363", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003417", "url": "https://www.yeastgenome.org/locus/S000003417" }, { "database": "iPTMnet", "id": "P36421", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36421" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Pro171", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "T", "comment": "Decreases cell population growth.", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" }, { "database": "PubMed", "id": "36307205", "url": "https://glygen.org/publication/PubMed/36307205" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Asp321", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "Y", "comment": "Inviable.", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" }, { "database": "PubMed", "id": "36307205", "url": "https://glygen.org/publication/PubMed/36307205" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Tyr43", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "G", "comment": "Decreases catalytic activity for L-tyrosine 400-fold, but allows the utilization of 3-iodo-L-tyrosine and other 3-modified tyrosines as substrates.", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" }, { "database": "PubMed", "id": "11530018", "url": "https://glygen.org/publication/PubMed/11530018" } ] } ] }, { "uniprot_canonical_ac": "P36421-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Gly45", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "Inviable.", "evidence": [ { "database": "UniProtKB", "id": "P36421", "url": "https://www.uniprot.org/uniprotkb/P36421" }, { "database": "PubMed", "id": "36307205", "url": "https://glygen.org/publication/PubMed/36307205" } ] } ] } ], "record_id": "P36421-1" }, { "uniprot_canonical_ac": "P36531-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36531", "url": "https://www.uniprot.org/uniprotkb/P36531" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 177, "chemical_mass": 20091.0, "gene_names": "MRPL36;MRPL36;YBR0918;bL31m", "protein_name": "Large ribosomal subunit protein bL31m", "disease": [], "cellular_component": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "P36531", "url": "https://www.uniprot.org/uniprotkb/P36531" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36531", "url": "https://www.uniprot.org/uniprotkb/P36531" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P36531", "url": "https://www.uniprot.org/uniprotkb/P36531" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P36531", "url": "https://www.uniprot.org/uniprotkb/P36531" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "P36531", "url": "https://www.uniprot.org/uniprotkb/P36531" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P36531-1" }, { "uniprot_canonical_ac": "P36775-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1133, "chemical_mass": 127112.0, "gene_names": "PIM1;LON;PIM1;YBL0440", "protein_name": "Lon protease homolog, mitochondrial", "disease": [ { "disease_id": "DOID:0111274", "name": "CODAS syndrome", "description": "A syndrome characterized by developmental delay, and cerebral, ocular, dental, auricular, and skeletal anomalies that has_material_basis_in homozygous or compound heterozygous mutation in LONP1 on 19p13.3.", "url": "https://disease-ontology.org/term/DOID:0111274", "evidence": [ { "id": "0111274", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111274" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitochondrial respiratory chain complex assembly", "id": "GO:0033108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033108", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "response to heat", "id": "GO:0009408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009408", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "regulation of mitochondrial DNA metabolic process", "id": "GO:1901858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901858", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "protein quality control for misfolded or incompletely synthesized proteins", "id": "GO:0006515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006515", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "mitochondrial DNA metabolic process", "id": "GO:0032042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032042", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "chaperone-mediated protein complex assembly", "id": "GO:0051131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051131", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "oxidation-dependent protein catabolic process", "id": "GO:0070407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070407", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "mitochondrial protein quality control", "id": "GO:0141164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141164", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "ATP-dependent peptidase activity", "id": "GO:0004176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004176", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P36775-1", "start_pos": "1036", "end_pos": "1036", "site_lbl": "Thr1036", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1036, "start_aa": "Thr", "end_pos": 1036, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1036", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P36775-1", "start_pos": "787", "end_pos": "787", "site_lbl": "Ser787", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P36775", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36775" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P36775-1", "start_pos": "842", "end_pos": "842", "site_lbl": "Ser842", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000118", "url": "https://www.yeastgenome.org/locus/S000000118" }, { "database": "iPTMnet", "id": "P36775", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36775" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36775-1", "start_pos": "846", "end_pos": "846", "site_lbl": "Ser846", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000118", "url": "https://www.yeastgenome.org/locus/S000000118" }, { "database": "iPTMnet", "id": "P36775", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36775" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36775-1", "start_pos": "850", "end_pos": "850", "site_lbl": "Ser850", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000118", "url": "https://www.yeastgenome.org/locus/S000000118" }, { "database": "iPTMnet", "id": "P36775", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36775" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36775-1", "start_pos": "902", "end_pos": "902", "site_lbl": "Ser902", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000118", "url": "https://www.yeastgenome.org/locus/S000000118" }, { "database": "iPTMnet", "id": "P36775", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36775" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P36775-1", "start_pos": "974", "end_pos": "974", "site_lbl": "Ser974", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000118", "url": "https://www.yeastgenome.org/locus/S000000118" }, { "database": "iPTMnet", "id": "P36775", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36775" }, { "database": "PubMed", "id": "36269765", "url": "https://glygen.org/publication/PubMed/36269765" } ] } ] }, { "uniprot_canonical_ac": "P36775-1", "start_pos": "1015", "end_pos": "1015", "site_lbl": "Ser1015", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes peptidase activity.", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" }, { "database": "PubMed", "id": "35143841", "url": "https://glygen.org/publication/PubMed/35143841" }, { "database": "PubMed", "id": "9405361", "url": "https://glygen.org/publication/PubMed/9405361" }, { "database": "PubMed", "id": "8810243", "url": "https://glygen.org/publication/PubMed/8810243" } ] } ] }, { "uniprot_canonical_ac": "P36775-1", "start_pos": "638", "end_pos": "638", "site_lbl": "Lys638", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "N", "comment": "Abolishes ATP-binding.", "evidence": [ { "database": "UniProtKB", "id": "P36775", "url": "https://www.uniprot.org/uniprotkb/P36775" }, { "database": "PubMed", "id": "8810243", "url": "https://glygen.org/publication/PubMed/8810243" }, { "database": "PubMed", "id": "9405361", "url": "https://glygen.org/publication/PubMed/9405361" } ] } ] } ], "record_id": "P36775-1" }, { "uniprot_canonical_ac": "P37012-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 569, "chemical_mass": 63089.0, "gene_names": "PGM2;GA-5;GAL5;PGM2;YM9718.04C", "protein_name": "Phosphoglucomutase 2", "disease": [ { "disease_id": "DOID:0080570", "name": "congenital disorder of glycosylation It", "description": "A congenital disorder of glycosylation I that is characterized by a wide range of clinical manifestations, most commonly presenting with bifid uvula with or without cleft palate at birth, associated with growth delay, hepatopathy with elevated aminotransferase serum levels, myopathy (including exercise-related fatigue, exercise intolerance, muscle weakness), intermittent hypoglycemia, and dilated cardiomyopathy and/or cardiac arrest, due to decreased phosphoglucomutase 1 enzyme activity and has_material_basis_in homozygous or compound heterozygous mutation in the PGM1 gene on chromosome 1p31.", "url": "https://disease-ontology.org/term/DOID:0080570", "evidence": [ { "id": "0080570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080570" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:3307", "name": "teratoma", "description": "A germ cell and embryonal cancer that is an encapsulated tumor with tissue or organ components resembling normal derivatives of all three germ layers.", "url": "https://disease-ontology.org/term/DOID:3307", "evidence": [ { "id": "3307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3307" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "phosphoglucomutase activity", "id": "GO:0004614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004614", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "glycogen biosynthetic process", "id": "GO:0005978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005978", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "glucose 1-phosphate metabolic process", "id": "GO:0019255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019255", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "intracellular monoatomic cation homeostasis", "id": "GO:0030003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030003", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "galactose catabolic process", "id": "GO:0019388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019388", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "UDP-alpha-D-glucose metabolic process", "id": "GO:0006011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006011", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "glucose 6-phosphate metabolic process", "id": "GO:0051156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051156", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" }, { "name": "trehalose biosynthetic process", "id": "GO:0005992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005992", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37012-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Thr111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37012" }, { "database": "SGD", "id": "S000004711", "url": "https://www.yeastgenome.org/locus/S000004711" } ] } ] }, { "uniprot_canonical_ac": "P37012-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Thr117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37012" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004711", "url": "https://www.yeastgenome.org/locus/S000004711" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37012-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Ser119", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37012", "url": "https://www.uniprot.org/uniprotkb/P37012" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37012" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004711", "url": "https://www.yeastgenome.org/locus/S000004711" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37012-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Thr20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004711", "url": "https://www.yeastgenome.org/locus/S000004711" }, { "database": "iPTMnet", "id": "P37012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37012" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37012-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004711", "url": "https://www.yeastgenome.org/locus/S000004711" }, { "database": "iPTMnet", "id": "P37012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37012" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37012-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004711", "url": "https://www.yeastgenome.org/locus/S000004711" }, { "database": "iPTMnet", "id": "P37012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37012" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37012-1", "start_pos": "380", "end_pos": "380", "site_lbl": "Ser380", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004711", "url": "https://www.yeastgenome.org/locus/S000004711" }, { "database": "iPTMnet", "id": "P37012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37012" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37012-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Ser461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004711", "url": "https://www.yeastgenome.org/locus/S000004711" }, { "database": "iPTMnet", "id": "P37012", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37012" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P37012-1" }, { "uniprot_canonical_ac": "P37020-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 779, "chemical_mass": 87592.0, "gene_names": "GEF1;CLCY1;CLC;GEF1;J1616", "protein_name": "Anion/proton exchange transporter GEF1", "disease": [ { "disease_id": "DOID:0050699", "name": "Dent disease", "description": "A renal tubular transport disease that is characterized by tubular proteinuria, hypercalciuria, calcium nephrolithiasis, nephrocalcinosis and chronic kidney failure.", "url": "https://disease-ontology.org/term/DOID:0050699", "evidence": [ { "id": "0050699", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050699" } ], "weight": 0.0 }, { "disease_id": "DOID:0080353", "name": "X-linked recessive hypophosphatemic rickets", "description": "A rickets that has_material_basis_in mutation in the CLCN5 gene on chromosome Xp11.22.", "url": "https://disease-ontology.org/term/DOID:0080353", "evidence": [ { "id": "0080353", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080353" } ], "weight": 0.0 }, { "disease_id": "DOID:0081453", "name": "Dent disease 1", "description": "A Dent disease that is characterized by manifestations of complex proximal tubule dysfunction with low-molecular-weight proteinuria, hypercalciuria, nephrolithiasis, nephrocalcinosis, and progressive renal failure and that has_material_basis_in mutation in the CLCN5 gene on chromosome Xp11. Extra-renal involvement is absent.", "url": "https://disease-ontology.org/term/DOID:0081453", "evidence": [ { "id": "0081453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081453" } ], "weight": 0.0 }, { "disease_id": "DOID:0110731", "name": "neuronal ceroid lipofuscinosis 3", "description": "A neuronal ceroid lipofuscinosis that is characterized by juvenile-onset of progressive dementia, seizures, and progressive visual failure and an ultrastructural pattern of lipopigment with a 'fingerprint' profile and has_material_basis_in homozygous or compound heterozygous mutation in the CLN3 gene on chromosome 16p11.", "url": "https://disease-ontology.org/term/DOID:0110731", "evidence": [ { "id": "0110731", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110731" } ], "weight": 0.0 }, { "disease_id": "DOID:0111798", "name": "X-linked nephrolithiasis type I", "description": "A renal tubular transport disease characterized by proximal renal tubular reabsorptive failure, hypercalciuria, nephrolithiasis, and renal insufficiency with absence of rickets that has_material_basis_in hemizygous or homozygous mutation in the CLCN5 gene on chromosome Xp11.23.", "url": "https://disease-ontology.org/term/DOID:0111798", "evidence": [ { "id": "0111798", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111798" } ], "weight": 0.0 }, { "disease_id": "DOID:0111815", "name": "low molecular weight proteinuria with hypercalciuric nephrocalcinosis", "description": "A Dent disease characterized by elevated levels of low molecular weight proteins in the urine, hypercalciuria, and nephrocalcinosis that has_material_basis_in hemizygous or homozygous mutation in the CLCN5 gene on chromosome Xp11.22.", "url": "https://disease-ontology.org/term/DOID:0111815", "evidence": [ { "id": "0111815", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111815" } ], "weight": 0.0 }, { "disease_id": "DOID:0112060", "name": "Raynaud-Claes syndrome", "description": "A syndromic X-linked intellectual disability characterized by borderline to severe intellectual disability, impaired language development, and variable additional features including; behavioral problems, psychiatric disorders, seizures, progressive ataxia, brain abnormalities, and facial dysmorphisms that has_material_basis_in heterozygous or hemizygous mutation in the CLCN4 gene on chromosome Xp22.2.", "url": "https://disease-ontology.org/term/DOID:0112060", "evidence": [ { "id": "0112060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112060" } ], "weight": 0.0 }, { "disease_id": "DOID:13533", "name": "osteopetrosis", "description": "An osteosclerosis that has_material_basis_in lack of bone resorption which results_in abnormally hard and brittle bones.", "url": "https://disease-ontology.org/term/DOID:13533", "evidence": [ { "id": "13533", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13533" } ], "weight": 0.0 }, { "disease_id": "DOID:447", "name": "renal tubular transport disease", "description": "", "url": "https://disease-ontology.org/term/DOID:447", "evidence": [ { "id": "447", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:447" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "Golgi medial cisterna", "id": "GO:0005797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005797", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular copper ion homeostasis", "id": "GO:0006878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006878", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" }, { "name": "regulation of iron ion transport", "id": "GO:0034756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034756", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" } ], "molecular_function": [ { "name": "voltage-gated chloride channel activity", "id": "GO:0005247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005247", "evidence": [ { "database": "UniProtKB", "id": "P37020", "url": "https://www.uniprot.org/uniprotkb/P37020" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37020-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Thr263", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 263, "start_aa": "Thr", "end_pos": 263, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr263", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P37020-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003801", "url": "https://www.yeastgenome.org/locus/S000003801" }, { "database": "iPTMnet", "id": "P37020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37020" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P37020-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003801", "url": "https://www.yeastgenome.org/locus/S000003801" }, { "database": "iPTMnet", "id": "P37020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37020" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P37020-1", "start_pos": "442", "end_pos": "442", "site_lbl": "Thr442", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003801", "url": "https://www.yeastgenome.org/locus/S000003801" }, { "database": "iPTMnet", "id": "P37020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37020" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37020-1", "start_pos": "443", "end_pos": "443", "site_lbl": "Ser443", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003801", "url": "https://www.yeastgenome.org/locus/S000003801" }, { "database": "iPTMnet", "id": "P37020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37020" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37020-1", "start_pos": "448", "end_pos": "448", "site_lbl": "Thr448", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003801", "url": "https://www.yeastgenome.org/locus/S000003801" }, { "database": "iPTMnet", "id": "P37020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37020" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37020-1", "start_pos": "619", "end_pos": "619", "site_lbl": "Ser619", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003801", "url": "https://www.yeastgenome.org/locus/S000003801" }, { "database": "iPTMnet", "id": "P37020", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37020" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P37020-1" }, { "uniprot_canonical_ac": "P37254-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37254", "url": "https://www.uniprot.org/uniprotkb/P37254" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 787, "chemical_mass": 88544.0, "gene_names": "ABZ1;ABZ1;N3286", "protein_name": "Aminodeoxychorismate synthase", "disease": [], "biological_process": [ { "name": "tetrahydrofolate biosynthetic process", "id": "GO:0046654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046654", "evidence": [ { "database": "UniProtKB", "id": "P37254", "url": "https://www.uniprot.org/uniprotkb/P37254" } ], "pmid": "" }, { "name": "4-aminobenzoate biosynthetic process", "id": "GO:0008153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008153", "evidence": [ { "database": "UniProtKB", "id": "P37254", "url": "https://www.uniprot.org/uniprotkb/P37254" } ], "pmid": "" }, { "name": "folic acid biosynthetic process", "id": "GO:0046656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046656", "evidence": [ { "database": "UniProtKB", "id": "P37254", "url": "https://www.uniprot.org/uniprotkb/P37254" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P37254", "url": "https://www.uniprot.org/uniprotkb/P37254" } ], "pmid": "" } ], "molecular_function": [ { "name": "4-amino-4-deoxychorismate synthase activity", "id": "GO:0046820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046820", "evidence": [ { "database": "UniProtKB", "id": "P37254", "url": "https://www.uniprot.org/uniprotkb/P37254" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37254-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005316", "url": "https://www.yeastgenome.org/locus/S000005316" }, { "database": "iPTMnet", "id": "P37254", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37254" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37254-1", "start_pos": "685", "end_pos": "685", "site_lbl": "Ser685", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37254", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37254" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005316", "url": "https://www.yeastgenome.org/locus/S000005316" } ] } ] } ], "record_id": "P37254-1" }, { "uniprot_canonical_ac": "P37291-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 469, "chemical_mass": 52218.0, "gene_names": "SHM2;L2156;SHM2;SHMT2", "protein_name": "Serine hydroxymethyltransferase, cytosolic", "disease": [ { "disease_id": "DOID:0070543", "name": "neurodevelopmental disorder with cardiomyopathy, spasticity, and brain abnormalities", "description": "An mitochondrial metabolism disease characterized by global neurodevelopmental delay, severely impaired intellectual development, poor overall growth, spasticity of the lower limbs resulting in gait difficulties, and progressive hypertrophic cardiomyopathy or cardiac developmental anomalies that has_material_basis_in homozygous or compound heterozygous mutation in the SHMT2 gene on chromosome 12q13.3.", "url": "https://disease-ontology.org/term/DOID:0070543", "evidence": [ { "id": "0070543", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070543" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" }, { "name": "one-carbon metabolic process", "id": "GO:0006730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" }, { "name": "tetrahydrofolate interconversion", "id": "GO:0035999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035999", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" }, { "name": "tetrahydrofolate metabolic process", "id": "GO:0046653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046653", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" }, { "name": "glycine biosynthetic process from serine", "id": "GO:0019264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019264", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" }, { "name": "glycine hydroxymethyltransferase activity", "id": "GO:0004372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004372", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37291-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Ser152", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Thr156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Tyr157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Thr20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Ser379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Ser385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Ser429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37291", "url": "https://www.uniprot.org/uniprotkb/P37291" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37291-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Thr98", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004048", "url": "https://www.yeastgenome.org/locus/S000004048" }, { "database": "iPTMnet", "id": "P37291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37291" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P37291-1" }, { "uniprot_canonical_ac": "P37292-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37292", "url": "https://www.uniprot.org/uniprotkb/P37292" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 490, "chemical_mass": 53686.0, "gene_names": "SHM1;SHM1;SHMT1;TMP3;YBR1732", "protein_name": "Serine hydroxymethyltransferase, mitochondrial", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P37292", "url": "https://www.uniprot.org/uniprotkb/P37292" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "P37292", "url": "https://www.uniprot.org/uniprotkb/P37292" } ], "pmid": "" }, { "name": "glycine hydroxymethyltransferase activity", "id": "GO:0004372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004372", "evidence": [ { "database": "UniProtKB", "id": "P37292", "url": "https://www.uniprot.org/uniprotkb/P37292" } ], "pmid": "" } ], "biological_process": [ { "name": "one-carbon metabolic process", "id": "GO:0006730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730", "evidence": [ { "database": "UniProtKB", "id": "P37292", "url": "https://www.uniprot.org/uniprotkb/P37292" } ], "pmid": "" }, { "name": "tetrahydrofolate interconversion", "id": "GO:0035999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035999", "evidence": [ { "database": "UniProtKB", "id": "P37292", "url": "https://www.uniprot.org/uniprotkb/P37292" } ], "pmid": "" }, { "name": "tetrahydrofolate metabolic process", "id": "GO:0046653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046653", "evidence": [ { "database": "UniProtKB", "id": "P37292", "url": "https://www.uniprot.org/uniprotkb/P37292" } ], "pmid": "" }, { "name": "glycine biosynthetic process from serine", "id": "GO:0019264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019264", "evidence": [ { "database": "UniProtKB", "id": "P37292", "url": "https://www.uniprot.org/uniprotkb/P37292" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37292-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Ser164", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Thr166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Ser169", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Thr210", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Ser385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Ser401", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37292-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Ser406", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000467", "url": "https://www.yeastgenome.org/locus/S000000467" }, { "database": "iPTMnet", "id": "P37292", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37292" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P37292-1" }, { "uniprot_canonical_ac": "P37296-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 890, "chemical_mass": 101661.0, "gene_names": "STV1;STV1;YM9796.07", "protein_name": "V-type proton ATPase subunit a, Golgi isoform", "disease": [ { "disease_id": "DOID:0061166", "name": "autosomal recessive distal renal tubular acidosis 3 with or without sensorineural hearing loss", "description": "A renal tubular transport disease characterized by the failure of the kidney to produce an appropriately acid urine in the presence of systemic metabolic acidosis or after acid loading, due to failure of hydrogen ion secretion or bicarbonate reabsorption in the distal nephron that has_material_basis_in homozygous mutation in the ATP6N1B gene on chromosome 7q34.", "url": "https://disease-ontology.org/term/DOID:0061166", "evidence": [ { "id": "0061166", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061166" } ], "weight": 0.0 }, { "disease_id": "DOID:0070134", "name": "autosomal recessive cutis laxa type IIA", "description": "An autosomal recessive cutis laxa type II classic type that has_material_basis_in homozygous or compound heterozygous mutations in the ATP6V0A2 gene on chromosome 12q24.", "url": "https://disease-ontology.org/term/DOID:0070134", "evidence": [ { "id": "0070134", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070134" } ], "weight": 0.0 }, { "disease_id": "DOID:0070390", "name": "developmental and epileptic encephalopathy 104", "description": "A developmental and epileptic encephalopathy characterized by developmental delay in the first few months of life and drug-resistant focal and generalized tonic-clonic seizures that has_material_basis_in heterozygous mutation in the ATP6V0A1 on chromosome 17q21.", "url": "https://disease-ontology.org/term/DOID:0070390", "evidence": [ { "id": "0070390", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070390" } ], "weight": 0.0 }, { "disease_id": "DOID:0110942", "name": "autosomal recessive osteopetrosis 1", "description": "An osteopetrosis characterized by autosomal recessive inheritance that has_material_basis_in homozygous or compound heterozygous mutation in the TCIRG1 gene on chromosome 11q13.2.", "url": "https://disease-ontology.org/term/DOID:0110942", "evidence": [ { "id": "0110942", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110942" } ], "weight": 0.0 }, { "disease_id": "DOID:0112171", "name": "wrinkly skin syndrome", "description": "A syndrome characterized by sagging or wrinkly skin, reduced skin elasticity, delayed closure of the fontanel, typically mild developmental delay, and variable other skeletal, neurological and facial features that has_material_basis_in homozygous or compound heterozygous mutation in the ATP6V0A2 gene on chromosome 12q24.31.", "url": "https://disease-ontology.org/term/DOID:0112171", "evidence": [ { "id": "0112171", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112171" } ], "weight": 0.0 }, { "disease_id": "DOID:11836", "name": "clubfoot", "description": "A bone development disease where one or both are inclined inwards, axially rotated outwards, and pointing downwards with concomitant soft tissue abnormalities.", "url": "https://disease-ontology.org/term/DOID:11836", "evidence": [ { "id": "11836", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11836" } ], "weight": 0.0 }, { "disease_id": "DOID:14219", "name": "renal tubular acidosis", "description": "A renal tubular transport disease characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic acidosis.", "url": "https://disease-ontology.org/term/DOID:14219", "evidence": [ { "id": "14219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14219" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase complex", "id": "GO:0016471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016471", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V0 domain", "id": "GO:0000220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000220", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" } ], "biological_process": [ { "name": "endosomal lumen acidification", "id": "GO:0048388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048388", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" }, { "name": "Golgi lumen acidification", "id": "GO:0061795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061795", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37296-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Thr172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37296" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004658", "url": "https://www.yeastgenome.org/locus/S000004658" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37296-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004658", "url": "https://www.yeastgenome.org/locus/S000004658" }, { "database": "iPTMnet", "id": "P37296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37296" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37296-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004658", "url": "https://www.yeastgenome.org/locus/S000004658" }, { "database": "iPTMnet", "id": "P37296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37296" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37296-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Thr219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004658", "url": "https://www.yeastgenome.org/locus/S000004658" }, { "database": "iPTMnet", "id": "P37296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37296" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37296-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Ser223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37296" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004658", "url": "https://www.yeastgenome.org/locus/S000004658" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37296-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Ser228", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37296", "url": "https://www.uniprot.org/uniprotkb/P37296" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37296" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004658", "url": "https://www.yeastgenome.org/locus/S000004658" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37296-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Ser551", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37296" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P37296-1", "start_pos": "735", "end_pos": "735", "site_lbl": "Ser735", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004658", "url": "https://www.yeastgenome.org/locus/S000004658" }, { "database": "iPTMnet", "id": "P37296", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37296" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P37296-1" }, { "uniprot_canonical_ac": "P37297-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1900, "chemical_mass": 214607.0, "gene_names": "STT4;L2142.4;STT4", "protein_name": "Phosphatidylinositol 4-kinase STT4", "disease": [ { "disease_id": "DOID:0060413", "name": "chromosome 22q11.2 deletion syndrome, distal", "description": "A chromosomal deletion syndrome that has_material_basis_in deletion of the chromosome 22q11.2 region, distinct from DiGeorge syndrome and velocardiofacial syndrome.", "url": "https://disease-ontology.org/term/DOID:0060413", "evidence": [ { "id": "0060413", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060413" } ], "weight": 0.0 }, { "disease_id": "DOID:0112347", "name": "hereditary spastic paraplegia 84", "description": "A hereditary spastic paraplegia characterized by onset in the first 2 decades of life of slowly progressive walking difficulties due to lower limb weakness, stiffness, and spasticity that has_material_basis_in homozygous or compound heterozygous mutation in the PI4KA gene on chromosome 22q11.21.", "url": "https://disease-ontology.org/term/DOID:0112347", "evidence": [ { "id": "0112347", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112347" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "1-phosphatidylinositol 4-kinase activity", "id": "GO:0004430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004430", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" } ], "biological_process": [ { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "phosphatidylinositol-mediated signaling", "id": "GO:0048015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "autophagosome-lysosome fusion", "id": "GO:0061909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061909", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "regulation of fungal-type cell wall organization", "id": "GO:0060237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060237", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" }, { "name": "microlipophagy", "id": "GO:0140504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140504", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37297-1", "start_pos": "1014", "end_pos": "1014", "site_lbl": "Thr1014", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004296", "url": "https://www.yeastgenome.org/locus/S000004296" }, { "database": "iPTMnet", "id": "P37297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37297-1", "start_pos": "459", "end_pos": "459", "site_lbl": "Ser459", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37297", "url": "https://www.uniprot.org/uniprotkb/P37297" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P37297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37297" }, { "database": "SGD", "id": "S000004296", "url": "https://www.yeastgenome.org/locus/S000004296" } ] } ] }, { "uniprot_canonical_ac": "P37297-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Thr470", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37297" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004296", "url": "https://www.yeastgenome.org/locus/S000004296" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37297-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Thr472", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004296", "url": "https://www.yeastgenome.org/locus/S000004296" }, { "database": "iPTMnet", "id": "P37297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37297" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37297-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Ser473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37297" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004296", "url": "https://www.yeastgenome.org/locus/S000004296" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37297-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Ser487", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004296", "url": "https://www.yeastgenome.org/locus/S000004296" }, { "database": "iPTMnet", "id": "P37297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37297-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Ser488", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004296", "url": "https://www.yeastgenome.org/locus/S000004296" }, { "database": "iPTMnet", "id": "P37297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37297-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004296", "url": "https://www.yeastgenome.org/locus/S000004296" }, { "database": "iPTMnet", "id": "P37297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37297-1", "start_pos": "513", "end_pos": "513", "site_lbl": "Ser513", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004296", "url": "https://www.yeastgenome.org/locus/S000004296" }, { "database": "iPTMnet", "id": "P37297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37297-1", "start_pos": "930", "end_pos": "930", "site_lbl": "Ser930", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37297" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004296", "url": "https://www.yeastgenome.org/locus/S000004296" } ] } ] } ], "record_id": "P37297-1" }, { "uniprot_canonical_ac": "P37298-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 181, "chemical_mass": 20249.0, "gene_names": "SDH4;ACN18;SDH4;YD9395.11", "protein_name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "disease": [ { "disease_id": "DOID:0050773", "name": "paraganglioma", "description": "A pheochromocytoma that arises in extraadrenal sympathetic ganglia.", "url": "https://disease-ontology.org/term/DOID:0050773", "evidence": [ { "id": "0050773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050773" } ], "weight": 0.0 }, { "disease_id": "DOID:0060537", "name": "mitochondrial complex II deficiency", "description": "A mitochondrial metabolism disease characterized by a highly variable phenotype. Some patients have multisystem involvement of the brain, heart, muscle, liver, and kidneys resulting in death in infancy, whereas others have only isolated cardiac or muscle involvement with onset in adulthood and normal cognition. It has_material_basis_in homozygous or compound heterozygous mutation in the nuclear-encoded SDHA gene on chromosome 5p, the nuclear-encoded SDHAF1 gene on chromosome 19q, or the nuclear-encoded SDHD gene on chromosome 11q23.", "url": "https://disease-ontology.org/term/DOID:0060537", "evidence": [ { "id": "0060537", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060537" } ], "weight": 0.0 }, { "disease_id": "DOID:0061216", "name": "pheochromocytoma/paraganglioma syndrome 1", "description": "A paraganglioma characterized by the development of neuroendocrine tumors, usually in adulthood that has material_basis_in heterozygous mutation in the SDHD gene.", "url": "https://disease-ontology.org/term/DOID:0061216", "evidence": [ { "id": "0061216", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061216" } ], "weight": 0.0 }, { "disease_id": "DOID:0080533", "name": "Carney-Stratakis syndrome", "description": "A syndrome that is characterized by the presence of multicentric paragangliomas and multifocal gastrointestinal stromal sarcoma tumors.", "url": "https://disease-ontology.org/term/DOID:0080533", "evidence": [ { "id": "0080533", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080533" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" } ], "pmid": "" }, { "name": "respiratory chain complex II (succinate dehydrogenase)", "id": "GO:0045273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045273", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" } ], "pmid": "" }, { "name": "mitochondrial electron transport, succinate to ubiquinone", "id": "GO:0006121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006121", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" } ], "pmid": "" }, { "name": "cellular respiration", "id": "GO:0045333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045333", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" } ], "pmid": "" }, { "name": "ubiquinone binding", "id": "GO:0048039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048039", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37298-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Thr18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37298" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P37298-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Thr20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37298", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37298" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P37298-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Phe100", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "V", "comment": "Impairs respiratory growth and reduces quinone reductase activity.", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" }, { "database": "PubMed", "id": "11279023", "url": "https://glygen.org/publication/PubMed/11279023" } ] } ] }, { "uniprot_canonical_ac": "P37298-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Ser102", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Impairs respiratory growth and reduces quinone reductase activity.", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" }, { "database": "PubMed", "id": "11279023", "url": "https://glygen.org/publication/PubMed/11279023" } ] } ] }, { "uniprot_canonical_ac": "P37298-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Cys109", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Decreases SDH cytochrome b content.", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" }, { "database": "PubMed", "id": "14672930", "url": "https://glygen.org/publication/PubMed/14672930" } ] } ] }, { "uniprot_canonical_ac": "P37298-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Tyr120", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "C", "comment": "Abolishes quinone reductase activity. Little effect on complex assembly.", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" }, { "database": "PubMed", "id": "17208193", "url": "https://glygen.org/publication/PubMed/17208193" } ] } ] }, { "uniprot_canonical_ac": "P37298-1", "start_pos": "130", "end_pos": "130", "site_lbl": "His130", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "L", "comment": "Reduces SDHFAD content. Probably impairs complex assembly.", "evidence": [ { "database": "UniProtKB", "id": "P37298", "url": "https://www.uniprot.org/uniprotkb/P37298" }, { "database": "PubMed", "id": "11279023", "url": "https://glygen.org/publication/PubMed/11279023" } ] } ] } ], "record_id": "P37298-1" }, { "uniprot_canonical_ac": "P37303-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37303", "url": "https://www.uniprot.org/uniprotkb/P37303" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 387, "chemical_mass": 42815.0, "gene_names": "GLY1;GLY1;SYGP-ORF34", "protein_name": "Low specificity L-threonine aldolase", "disease": [], "biological_process": [ { "name": "glycine biosynthetic process", "id": "GO:0006545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006545", "evidence": [ { "database": "UniProtKB", "id": "P37303", "url": "https://www.uniprot.org/uniprotkb/P37303" } ], "pmid": "" }, { "name": "L-threonine catabolic process", "id": "GO:0006567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006567", "evidence": [ { "database": "UniProtKB", "id": "P37303", "url": "https://www.uniprot.org/uniprotkb/P37303" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P37303", "url": "https://www.uniprot.org/uniprotkb/P37303" } ], "pmid": "" } ], "molecular_function": [ { "name": "L-allo-threonine aldolase activity", "id": "GO:0008732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008732", "evidence": [ { "database": "UniProtKB", "id": "P37303", "url": "https://www.uniprot.org/uniprotkb/P37303" } ], "pmid": "" }, { "name": "threonine aldolase activity", "id": "GO:0004793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004793", "evidence": [ { "database": "UniProtKB", "id": "P37303", "url": "https://www.uniprot.org/uniprotkb/P37303" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37303-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Tyr10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Ser132", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Ser271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "345", "end_pos": "345", "site_lbl": "Ser345", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Thr362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Tyr365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37303", "url": "https://www.uniprot.org/uniprotkb/P37303" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Ser369", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37303", "url": "https://www.uniprot.org/uniprotkb/P37303" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Thr370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37303", "url": "https://www.uniprot.org/uniprotkb/P37303" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37303-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Tyr385", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000772", "url": "https://www.yeastgenome.org/locus/S000000772" }, { "database": "iPTMnet", "id": "P37303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37303" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P37303-1" }, { "uniprot_canonical_ac": "P37370-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 817, "chemical_mass": 82594.0, "gene_names": "VRP1;END5;L8300.13;MDP2;VRP1;YLR337W", "protein_name": "Verprolin", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "pmid": "" }, { "name": "positive regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:2000601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000601", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "pmid": "" }, { "name": "actin cortical patch localization", "id": "GO:0051666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051666", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "pmid": "" }, { "name": "bipolar cellular bud site selection", "id": "GO:0007121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007121", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "pmid": "" } ], "cellular_component": [ { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "pmid": "" }, { "name": "incipient cellular bud site", "id": "GO:0000131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000131", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37370-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Asn109", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 109, "start_aa": "Asn", "end_pos": 109, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn109", "evidence": [ { "id": "P37370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37370#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "212", "end_pos": "212", "site_lbl": "Asn212", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 212, "start_aa": "Asn", "end_pos": 212, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn212", "evidence": [ { "id": "P37370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37370#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Thr244", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 244, "start_aa": "Thr", "end_pos": 244, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr244", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Thr246", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 246, "start_aa": "Thr", "end_pos": 246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Ser262", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 262, "start_aa": "Ser", "end_pos": 262, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser262", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Ser265", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 265, "start_aa": "Ser", "end_pos": 265, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser265", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 266, "start_aa": "Ser", "end_pos": 266, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser266", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Ser293", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 293, "start_aa": "Ser", "end_pos": 293, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser293", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Ser294", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 294, "start_aa": "Ser", "end_pos": 294, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser294", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Asn337", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 337, "start_aa": "Asn", "end_pos": 337, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn337", "evidence": [ { "id": "P37370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37370#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Ser361", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 361, "start_aa": "Ser", "end_pos": 361, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser361", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 362, "start_aa": "Ser", "end_pos": 362, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser362", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Ser364", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 364, "start_aa": "Ser", "end_pos": 364, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser364", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Ser367", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 367, "start_aa": "Ser", "end_pos": 367, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser367", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Thr376", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 376, "start_aa": "Thr", "end_pos": 376, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr376", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Asn383", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 383, "start_aa": "Asn", "end_pos": 383, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn383", "evidence": [ { "id": "P37370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37370#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "384", "end_pos": "384", "site_lbl": "Thr384", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 384, "start_aa": "Thr", "end_pos": 384, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr384", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "385", "end_pos": "385", "site_lbl": "Thr385", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 385, "start_aa": "Thr", "end_pos": 385, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr385", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "386", "end_pos": "386", "site_lbl": "Ser386", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 386, "start_aa": "Ser", "end_pos": 386, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser386", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Thr471", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 471, "start_aa": "Thr", "end_pos": 471, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr471", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 53, "start_aa": "Ser", "end_pos": 53, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser53", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Thr585", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 585, "start_aa": "Thr", "end_pos": 585, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr585", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Ser63", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 63, "start_aa": "Ser", "end_pos": 63, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser63", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 64, "start_aa": "Ser", "end_pos": 64, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser64", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Ser66", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 66, "start_aa": "Ser", "end_pos": 66, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser66", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Ser68", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 68, "start_aa": "Ser", "end_pos": 68, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser68", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 69, "start_aa": "Ser", "end_pos": 69, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser69", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 73, "start_aa": "Ser", "end_pos": 73, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser73", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Ser74", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 74, "start_aa": "Ser", "end_pos": 74, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser74", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P37370", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P37370" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "784", "end_pos": "784", "site_lbl": "Asn784", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 784, "start_aa": "Asn", "end_pos": 784, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn784", "evidence": [ { "id": "P37370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37370#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "796", "end_pos": "796", "site_lbl": "Asn796", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 796, "start_aa": "Asn", "end_pos": 796, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn796", "evidence": [ { "id": "P37370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37370#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Ser210", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Ser211", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Thr257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Thr365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "462", "end_pos": "462", "site_lbl": "Ser462", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Ser463", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "464", "end_pos": "464", "site_lbl": "Ser464", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Ser466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "467", "end_pos": "467", "site_lbl": "Ser467", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "519", "end_pos": "519", "site_lbl": "Ser519", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "522", "end_pos": "522", "site_lbl": "Ser522", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "524", "end_pos": "524", "site_lbl": "Ser524", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "651", "end_pos": "651", "site_lbl": "Ser651", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "695", "end_pos": "695", "site_lbl": "Ser695", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "701", "end_pos": "701", "site_lbl": "Thr701", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "703", "end_pos": "703", "site_lbl": "Ser703", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "709", "end_pos": "709", "site_lbl": "Ser709", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "711", "end_pos": "711", "site_lbl": "Ser711", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "712", "end_pos": "712", "site_lbl": "Thr712", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Thr715", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "717", "end_pos": "717", "site_lbl": "Thr717", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "718", "end_pos": "718", "site_lbl": "Ser718", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "720", "end_pos": "720", "site_lbl": "Ser720", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "21725298", "url": "https://glygen.org/publication/PubMed/21725298" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "722", "end_pos": "722", "site_lbl": "Ser722", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "731", "end_pos": "731", "site_lbl": "Ser731", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "735", "end_pos": "735", "site_lbl": "Ser735", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "736", "end_pos": "736", "site_lbl": "Thr736", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "756", "end_pos": "756", "site_lbl": "Thr756", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "760", "end_pos": "760", "site_lbl": "Ser760", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37370-1", "start_pos": "762", "end_pos": "762", "site_lbl": "Ser762", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37370", "url": "https://www.uniprot.org/uniprotkb/P37370" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P37370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37370" }, { "database": "SGD", "id": "S000004329", "url": "https://www.yeastgenome.org/locus/S000004329" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P37370-1" }, { "uniprot_canonical_ac": "P37838-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P37838", "url": "https://www.uniprot.org/uniprotkb/P37838" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 685, "chemical_mass": 77825.0, "gene_names": "NOP4;NOP4;NOP77", "protein_name": "Nucleolar protein 4", "disease": [ { "disease_id": "DOID:0112244", "name": "alopecia, neurologic defects, and endocrinopathy syndrome", "description": "A syndrome characterized by alopecia, neurologic defects, and endocrinopathy that has_material_basis_in homozygous or compound heterozygous mutation in the RBM28 gene on chromosome 7q32.1.", "url": "https://disease-ontology.org/term/DOID:0112244", "evidence": [ { "id": "0112244", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112244" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P37838", "url": "https://www.uniprot.org/uniprotkb/P37838" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P37838", "url": "https://www.uniprot.org/uniprotkb/P37838" } ], "pmid": "" }, { "name": "large ribosomal subunit rRNA binding", "id": "GO:0070180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070180", "evidence": [ { "database": "UniProtKB", "id": "P37838", "url": "https://www.uniprot.org/uniprotkb/P37838" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P37838", "url": "https://www.uniprot.org/uniprotkb/P37838" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P37838", "url": "https://www.uniprot.org/uniprotkb/P37838" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P37838", "url": "https://www.uniprot.org/uniprotkb/P37838" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "P37838", "url": "https://www.uniprot.org/uniprotkb/P37838" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P37838-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Ser111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Thr118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Thr173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Ser247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37838", "url": "https://www.uniprot.org/uniprotkb/P37838" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Thr379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P37838", "url": "https://www.uniprot.org/uniprotkb/P37838" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "444", "end_pos": "444", "site_lbl": "Tyr444", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "656", "end_pos": "656", "site_lbl": "Thr656", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P37838-1", "start_pos": "657", "end_pos": "657", "site_lbl": "Thr657", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005964", "url": "https://www.yeastgenome.org/locus/S000005964" }, { "database": "iPTMnet", "id": "P37838", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P37838" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P37838-1" }, { "uniprot_canonical_ac": "P38009-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38009", "url": "https://www.uniprot.org/uniprotkb/P38009" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 592, "chemical_mass": 65263.0, "gene_names": "ADE17;ADE17;YM8564.02C", "protein_name": "Bifunctional purine biosynthesis protein ADE17", "disease": [ { "disease_id": "DOID:653", "name": "purine-pyrimidine metabolic disorder", "description": "An inherited metabolic disorder involving dysfunction of purine and pyrimidine metabolism.", "url": "https://disease-ontology.org/term/DOID:653", "evidence": [ { "id": "653", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:653" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38009", "url": "https://www.uniprot.org/uniprotkb/P38009" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38009", "url": "https://www.uniprot.org/uniprotkb/P38009" } ], "pmid": "" } ], "biological_process": [ { "name": "purine nucleotide biosynthetic process", "id": "GO:0006164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006164", "evidence": [ { "database": "UniProtKB", "id": "P38009", "url": "https://www.uniprot.org/uniprotkb/P38009" } ], "pmid": "" }, { "name": "'de novo' IMP biosynthetic process", "id": "GO:0006189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006189", "evidence": [ { "database": "UniProtKB", "id": "P38009", "url": "https://www.uniprot.org/uniprotkb/P38009" } ], "pmid": "" } ], "molecular_function": [ { "name": "IMP cyclohydrolase activity", "id": "GO:0003937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003937", "evidence": [ { "database": "UniProtKB", "id": "P38009", "url": "https://www.uniprot.org/uniprotkb/P38009" } ], "pmid": "" }, { "name": "phosphoribosylaminoimidazolecarboxamide formyltransferase activity", "id": "GO:0004643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004643", "evidence": [ { "database": "UniProtKB", "id": "P38009", "url": "https://www.uniprot.org/uniprotkb/P38009" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38009-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Tyr13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004727", "url": "https://www.yeastgenome.org/locus/S000004727" }, { "database": "iPTMnet", "id": "P38009", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38009" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38009-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004727", "url": "https://www.yeastgenome.org/locus/S000004727" }, { "database": "iPTMnet", "id": "P38009", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38009" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38009-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Ser429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004727", "url": "https://www.yeastgenome.org/locus/S000004727" }, { "database": "iPTMnet", "id": "P38009", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38009" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38009-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Tyr434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004727", "url": "https://www.yeastgenome.org/locus/S000004727" }, { "database": "iPTMnet", "id": "P38009", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38009" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P38009-1", "start_pos": "520", "end_pos": "520", "site_lbl": "Thr520", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004727", "url": "https://www.yeastgenome.org/locus/S000004727" }, { "database": "iPTMnet", "id": "P38009", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38009" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38009-1", "start_pos": "565", "end_pos": "565", "site_lbl": "Ser565", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004727", "url": "https://www.yeastgenome.org/locus/S000004727" }, { "database": "iPTMnet", "id": "P38009", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38009" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38009-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004727", "url": "https://www.yeastgenome.org/locus/S000004727" }, { "database": "iPTMnet", "id": "P38009", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38009" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38009-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38009", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38009" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004727", "url": "https://www.yeastgenome.org/locus/S000004727" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38009-1" }, { "uniprot_canonical_ac": "P38011-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 319, "chemical_mass": 34805.0, "gene_names": "ASC1;ASC1;ASU9;CPC2;NAD1;YM9718.15C", "protein_name": "Small ribosomal subunit protein RACK1", "disease": [ { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 } ], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "nonfunctional rRNA decay", "id": "GO:0070651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070651", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "maintenance of translational fidelity", "id": "GO:1990145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990145", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "mRNA destabilization", "id": "GO:0061157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061157", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "ribosome-associated ubiquitin-dependent protein catabolic process", "id": "GO:1990116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990116", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "regulation of amino acid metabolic process", "id": "GO:0006521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006521", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "negative regulation of translational frameshifting", "id": "GO:2001125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001125", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "negative regulation of glucose mediated signaling pathway", "id": "GO:1902660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902660", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase C binding", "id": "GO:0005080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005080", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "translation regulator activity", "id": "GO:0045182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045182", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" }, { "name": "GDP-dissociation inhibitor activity", "id": "GO:0005092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005092", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38011-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Tyr100", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Thr12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Ser152", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Ser166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Thr168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Tyr250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Ser282", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Thr300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Thr48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Thr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Thr96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38011", "url": "https://www.uniprot.org/uniprotkb/P38011" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38011-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Thr99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38011", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38011" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000004722", "url": "https://www.yeastgenome.org/locus/S000004722" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38011-1" }, { "uniprot_canonical_ac": "P38013-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 176, "chemical_mass": 19115.0, "gene_names": "AHP1;AHP1;L2916;L9354.5", "protein_name": "Peroxiredoxin AHP1", "disease": [ { "disease_id": "DOID:10459", "name": "common cold", "description": "An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus.", "url": "https://disease-ontology.org/term/DOID:10459", "evidence": [ { "id": "10459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10459" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "pmid": "" }, { "name": "hydrogen peroxide catabolic process", "id": "GO:0042744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042744", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "pmid": "" }, { "name": "response to metal ion", "id": "GO:0010038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010038", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "pmid": "" } ], "molecular_function": [ { "name": "thioredoxin peroxidase activity", "id": "GO:0008379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008379", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38013-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Thr109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Tyr14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Thr165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Ser168", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Thr36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Ser40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Thr52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004099", "url": "https://www.yeastgenome.org/locus/S000004099" }, { "database": "iPTMnet", "id": "P38013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38013" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Cys120", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on tert-butyl hydroperoxide consumption.", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" }, { "database": "PubMed", "id": "22474296", "url": "https://glygen.org/publication/PubMed/22474296" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Cys31", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes catalytic activity, but does not impact URM1 conjugation.", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" }, { "database": "PubMed", "id": "22474296", "url": "https://glygen.org/publication/PubMed/22474296" }, { "database": "PubMed", "id": "32004955", "url": "https://glygen.org/publication/PubMed/32004955" }, { "database": "PubMed", "id": "36102610", "url": "https://glygen.org/publication/PubMed/36102610" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Lys32", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Prevents urmylation of AHP1.", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" }, { "database": "PubMed", "id": "21209336", "url": "https://glygen.org/publication/PubMed/21209336" } ] } ] }, { "uniprot_canonical_ac": "P38013-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Cys62", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes catalytic activity, and completely abolishes URM1 conjugation.", "evidence": [ { "database": "UniProtKB", "id": "P38013", "url": "https://www.uniprot.org/uniprotkb/P38013" }, { "database": "PubMed", "id": "22474296", "url": "https://glygen.org/publication/PubMed/22474296" }, { "database": "PubMed", "id": "32004955", "url": "https://glygen.org/publication/PubMed/32004955" }, { "database": "PubMed", "id": "36102610", "url": "https://glygen.org/publication/PubMed/36102610" } ] } ] } ], "record_id": "P38013-1" }, { "uniprot_canonical_ac": "P38041-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 980, "chemical_mass": 109295.0, "gene_names": "BOI1;BOB1;BOI1;GIN7;YBL0717", "protein_name": "BEM1-interacting protein 1", "disease": [], "biological_process": [ { "name": "septum digestion after cytokinesis", "id": "GO:0000920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000920", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "receptor recycling", "id": "GO:0001881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001881", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "vesicle fusion to plasma membrane", "id": "GO:0099500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099500", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "budding cell apical bud growth", "id": "GO:0007118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007118", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" } ], "molecular_function": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "site of polarized growth", "id": "GO:0030427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030427", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "cellular bud", "id": "GO:0005933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005933", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38041-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 104, "start_aa": "Ser", "end_pos": 104, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser104", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 106, "start_aa": "Ser", "end_pos": 106, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser106", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38041", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38041" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Ser128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Ser149", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Thr151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Thr158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Thr166", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Ser194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Thr207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Ser209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Ser213", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Ser214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "332", "end_pos": "332", "site_lbl": "Ser332", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Ser340", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Ser347", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Ser348", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Ser349", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Thr351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Thr352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Ser358", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Ser402", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Tyr403", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Ser405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Ser412", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "414", "end_pos": "414", "site_lbl": "Ser414", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Thr431", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "453", "end_pos": "453", "site_lbl": "Ser453", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Ser471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Ser473", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "485", "end_pos": "485", "site_lbl": "Ser485", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "488", "end_pos": "488", "site_lbl": "Thr488", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "491", "end_pos": "491", "site_lbl": "Thr491", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Ser494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Thr506", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Ser507", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "514", "end_pos": "514", "site_lbl": "Ser514", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Thr523", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "525", "end_pos": "525", "site_lbl": "Ser525", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "527", "end_pos": "527", "site_lbl": "Ser527", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "528", "end_pos": "528", "site_lbl": "Ser528", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "537", "end_pos": "537", "site_lbl": "Ser537", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "540", "end_pos": "540", "site_lbl": "Ser540", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Ser544", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "545", "end_pos": "545", "site_lbl": "Ser545", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Ser564", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "578", "end_pos": "578", "site_lbl": "Ser578", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "589", "end_pos": "589", "site_lbl": "Ser589", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "590", "end_pos": "590", "site_lbl": "Ser590", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "593", "end_pos": "593", "site_lbl": "Ser593", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Ser596", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "597", "end_pos": "597", "site_lbl": "Ser597", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Ser599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Ser601", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Thr604", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "605", "end_pos": "605", "site_lbl": "Ser605", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "607", "end_pos": "607", "site_lbl": "Thr607", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Thr610", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "622", "end_pos": "622", "site_lbl": "Ser622", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "624", "end_pos": "624", "site_lbl": "Ser624", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Ser626", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "634", "end_pos": "634", "site_lbl": "Ser634", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "636", "end_pos": "636", "site_lbl": "Ser636", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "637", "end_pos": "637", "site_lbl": "Tyr637", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Ser640", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "644", "end_pos": "644", "site_lbl": "Ser644", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Thr647", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "28265048", "url": "https://glygen.org/publication/PubMed/28265048" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "648", "end_pos": "648", "site_lbl": "Ser648", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Thr652", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "653", "end_pos": "653", "site_lbl": "Ser653", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "655", "end_pos": "655", "site_lbl": "Ser655", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "659", "end_pos": "659", "site_lbl": "Ser659", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "661", "end_pos": "661", "site_lbl": "Ser661", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "668", "end_pos": "668", "site_lbl": "Ser668", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "670", "end_pos": "670", "site_lbl": "Thr670", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "672", "end_pos": "672", "site_lbl": "Thr672", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "673", "end_pos": "673", "site_lbl": "Ser673", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "674", "end_pos": "674", "site_lbl": "Ser674", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "681", "end_pos": "681", "site_lbl": "Ser681", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Ser684", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "720", "end_pos": "720", "site_lbl": "Ser720", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "725", "end_pos": "725", "site_lbl": "Ser725", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "729", "end_pos": "729", "site_lbl": "Ser729", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "735", "end_pos": "735", "site_lbl": "Ser735", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "737", "end_pos": "737", "site_lbl": "Ser737", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "762", "end_pos": "762", "site_lbl": "Thr762", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "767", "end_pos": "767", "site_lbl": "Ser767", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Ser86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Thr88", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "919", "end_pos": "919", "site_lbl": "Thr919", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "967", "end_pos": "967", "site_lbl": "Tyr967", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000181", "url": "https://www.yeastgenome.org/locus/S000000181" }, { "database": "iPTMnet", "id": "P38041", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38041" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "785", "end_pos": "785", "site_lbl": "Lys785", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "Affects the binding to phospholipids and impairs localization to the bud, but does not affect the localization to the neck.", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "12097146", "url": "https://glygen.org/publication/PubMed/12097146" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "786", "end_pos": "786", "site_lbl": "Lys786", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Affects the binding to phospholipids and impairs localization to the bud, but does not affect the localization to the neck.", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "12097146", "url": "https://glygen.org/publication/PubMed/12097146" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "793", "end_pos": "793", "site_lbl": "Thr793", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Affects the binding to phospholipids and impairs localization to the bud, but does not affect the localization to the neck.", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "12097146", "url": "https://glygen.org/publication/PubMed/12097146" } ] } ] }, { "uniprot_canonical_ac": "P38041-1", "start_pos": "795", "end_pos": "795", "site_lbl": "Lys795", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "Affects the binding to phospholipids and impairs localization to the bud, but does not affect the localization to the neck.", "evidence": [ { "database": "UniProtKB", "id": "P38041", "url": "https://www.uniprot.org/uniprotkb/P38041" }, { "database": "PubMed", "id": "12097146", "url": "https://glygen.org/publication/PubMed/12097146" } ] } ] } ], "record_id": "P38041-1" }, { "uniprot_canonical_ac": "P38042-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 758, "chemical_mass": 85396.0, "gene_names": "CDC27;APC3;CDC27;SNB1;YBL0718", "protein_name": "Anaphase-promoting complex subunit CDC27", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "pmid": "" }, { "name": "regulation of meiotic cell cycle", "id": "GO:0051445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051445", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38042-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Ser215", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 215, "start_aa": "Ser", "end_pos": 215, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser215", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38042", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38042" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 217, "start_aa": "Ser", "end_pos": 217, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser217", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38042", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38042" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 224, "start_aa": "Ser", "end_pos": 224, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser224", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38042", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38042" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 225, "start_aa": "Ser", "end_pos": 225, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser225", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38042", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38042" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Ser228", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 228, "start_aa": "Ser", "end_pos": 228, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser228", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38042", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38042" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 230, "start_aa": "Ser", "end_pos": 230, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser230", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38042", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38042" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Ser232", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 232, "start_aa": "Ser", "end_pos": 232, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser232", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38042", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38042" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000180", "url": "https://www.yeastgenome.org/locus/S000000180" }, { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-304; A-328; A-351 and A-397.", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Thr302", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000180", "url": "https://www.yeastgenome.org/locus/S000000180" }, { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Thr304", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000180", "url": "https://www.yeastgenome.org/locus/S000000180" }, { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-267; A-304; A-351 and A-397.", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Ser328", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000180", "url": "https://www.yeastgenome.org/locus/S000000180" }, { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-267; A-304; A-328 and A-397.", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000180", "url": "https://www.yeastgenome.org/locus/S000000180" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Thr351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000180", "url": "https://www.yeastgenome.org/locus/S000000180" }, { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-267; A-304; A-328 and A-304.", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000180", "url": "https://www.yeastgenome.org/locus/S000000180" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Thr397", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000180", "url": "https://www.yeastgenome.org/locus/S000000180" }, { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes phosphorylation; when associated with A-304; A-328; A-351 and A-397.", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" }, { "database": "PubMed", "id": "10871279", "url": "https://glygen.org/publication/PubMed/10871279" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Ser404", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000180", "url": "https://www.yeastgenome.org/locus/S000000180" }, { "database": "iPTMnet", "id": "P38042", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38042" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Gly613", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In CDC27-633; G2/M cell cycle arrest at 35 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" }, { "database": "PubMed", "id": "1819514", "url": "https://glygen.org/publication/PubMed/1819514" } ] } ] }, { "uniprot_canonical_ac": "P38042-1", "start_pos": "614", "end_pos": "614", "site_lbl": "Leu614", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "GL", "comment": "Abolishes interaction with CDC23.", "evidence": [ { "database": "UniProtKB", "id": "P38042", "url": "https://www.uniprot.org/uniprotkb/P38042" }, { "database": "PubMed", "id": "7925276", "url": "https://glygen.org/publication/PubMed/7925276" } ] } ] } ], "record_id": "P38042-1" }, { "uniprot_canonical_ac": "P38063-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38063", "url": "https://www.uniprot.org/uniprotkb/P38063" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 326, "chemical_mass": 35720.0, "gene_names": "PRS4;PRPS4;PRS4;YBL0619", "protein_name": "Ribose-phosphate pyrophosphokinase 4", "disease": [ { "disease_id": "DOID:0050647", "name": "Arts syndrome", "description": "An X-linked disease that is characterized by profound congenital sensorineural hearing impairment, early-onset hypotonia, delayed motor development, mild to moderate intellectual disability, ataxia, and increased risk of infection and has_material_basis_in mutations of the PRPS1 gene.", "url": "https://disease-ontology.org/term/DOID:0050647", "evidence": [ { "id": "0050647", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050647" } ], "weight": 0.0 }, { "disease_id": "DOID:0110210", "name": "Charcot-Marie-Tooth disease X-linked recessive 5", "description": "A Charcot-Marie-Tooth disease X-linked that has_material_basis_in loss-of-function mutation in the PRPS1 gene on chromosome Xq22.", "url": "https://disease-ontology.org/term/DOID:0110210", "evidence": [ { "id": "0110210", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110210" } ], "weight": 0.0 }, { "disease_id": "DOID:0111260", "name": "phosphoribosylpyrophosphate synthetase superactivity", "description": "An inherited metabolic disorder characterized by increased synthesis of phosphoribosylpyrophosphate resulting in increased production of uric acid and purine that has_material_basis_in X-linked recessive inheritance of mutations in PRPS1 on Xq22.3 that result in increased activity of the gene. The mild form of the disease has late-juvenile or early adult onset while the more severe form has infantile or early-childhood onset.", "url": "https://disease-ontology.org/term/DOID:0111260", "evidence": [ { "id": "0111260", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111260" } ], "weight": 0.0 }, { "disease_id": "DOID:0111739", "name": "X-linked deafness 1", "description": "An X-linked nonsyndromic deafness characterized by congenital profound sensorineural hearing loss in males and mild to moderate high-frequency hearing loss in heterozygous females that has_material_basis_in mutation in the PRPS1 gene on chromosome Xq22.3.", "url": "https://disease-ontology.org/term/DOID:0111739", "evidence": [ { "id": "0111739", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111739" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:13189", "name": "gout", "description": "An arthritis that has_material_basis_in uric acid crystal deposits located_in joint.", "url": "https://disease-ontology.org/term/DOID:13189", "evidence": [ { "id": "13189", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13189" } ], "weight": 0.0 }, { "disease_id": "DOID:8501", "name": "fundus dystrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:8501", "evidence": [ { "id": "8501", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8501" } ], "weight": 0.0 }, { "disease_id": "DOID:9409", "name": "diabetes insipidus", "description": "A kidney disease that is characterized by polydipsia and polyuria with a dilute urine having a specific gravity less than 1.010, hypernatremia, and dehydration.", "url": "https://disease-ontology.org/term/DOID:9409", "evidence": [ { "id": "9409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9409" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ribose phosphate diphosphokinase complex", "id": "GO:0002189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002189", "evidence": [ { "database": "UniProtKB", "id": "P38063", "url": "https://www.uniprot.org/uniprotkb/P38063" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38063", "url": "https://www.uniprot.org/uniprotkb/P38063" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P38063", "url": "https://www.uniprot.org/uniprotkb/P38063" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38063", "url": "https://www.uniprot.org/uniprotkb/P38063" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "P38063", "url": "https://www.uniprot.org/uniprotkb/P38063" } ], "pmid": "" }, { "name": "ribose phosphate diphosphokinase activity", "id": "GO:0004749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004749", "evidence": [ { "database": "UniProtKB", "id": "P38063", "url": "https://www.uniprot.org/uniprotkb/P38063" } ], "pmid": "" } ], "biological_process": [ { "name": "ribonucleoside monophosphate biosynthetic process", "id": "GO:0009156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009156", "evidence": [ { "database": "UniProtKB", "id": "P38063", "url": "https://www.uniprot.org/uniprotkb/P38063" } ], "pmid": "" }, { "name": "5-phosphoribose 1-diphosphate biosynthetic process", "id": "GO:0006015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006015", "evidence": [ { "database": "UniProtKB", "id": "P38063", "url": "https://www.uniprot.org/uniprotkb/P38063" } ], "pmid": "" }, { "name": "purine nucleotide biosynthetic process", "id": "GO:0006164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006164", "evidence": [ { "database": "UniProtKB", "id": "P38063", "url": "https://www.uniprot.org/uniprotkb/P38063" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38063-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000164", "url": "https://www.yeastgenome.org/locus/S000000164" }, { "database": "iPTMnet", "id": "P38063", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38063" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38063-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000164", "url": "https://www.yeastgenome.org/locus/S000000164" }, { "database": "iPTMnet", "id": "P38063", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38063" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38063-1" }, { "uniprot_canonical_ac": "P38069-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38069", "url": "https://www.uniprot.org/uniprotkb/P38069" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 597, "chemical_mass": 67774.0, "gene_names": "MNN2;CRV4;LDB8;MNN2;TTP1;YBR0220", "protein_name": "Alpha-1,2-mannosyltransferase MNN2", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P38069", "url": "https://www.uniprot.org/uniprotkb/P38069" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P38069", "url": "https://www.uniprot.org/uniprotkb/P38069" } ], "pmid": "" } ], "biological_process": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "P38069", "url": "https://www.uniprot.org/uniprotkb/P38069" } ], "pmid": "" }, { "name": "mannan biosynthetic process", "id": "GO:0046354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046354", "evidence": [ { "database": "UniProtKB", "id": "P38069", "url": "https://www.uniprot.org/uniprotkb/P38069" } ], "pmid": "" } ], "molecular_function": [ { "name": "alpha-1,2-mannosyltransferase activity", "id": "GO:0000026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000026", "evidence": [ { "database": "UniProtKB", "id": "P38069", "url": "https://www.uniprot.org/uniprotkb/P38069" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38069-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Asn34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 34, "start_aa": "Asn", "end_pos": 34, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn34", "evidence": [ { "id": "P38069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38069#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38069-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Asn363", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 363, "start_aa": "Asn", "end_pos": 363, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn363", "evidence": [ { "id": "P38069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38069#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38069-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Asn473", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 473, "start_aa": "Asn", "end_pos": 473, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn473", "evidence": [ { "id": "P38069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38069#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38069-1", "start_pos": "570", "end_pos": "570", "site_lbl": "Thr570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000219", "url": "https://www.yeastgenome.org/locus/S000000219" }, { "database": "iPTMnet", "id": "P38069", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38069" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38069-1" }, { "uniprot_canonical_ac": "P38070-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 525, "chemical_mass": 59591.0, "gene_names": "YPK3;YBR0312;YPK3", "protein_name": "Serine/threonine-protein kinase YPK3", "disease": [ { "disease_id": "DOID:0050668", "name": "alcohol-related birth defects", "description": "A fetal alcohol spectrum disorder that results in damage to organs, bones, or muscles due to prenatal alcohol exposure.", "url": "https://disease-ontology.org/term/DOID:0050668", "evidence": [ { "id": "0050668", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050668" } ], "weight": 0.0 }, { "disease_id": "DOID:0112019", "name": "non-syndromic X-linked intellectual disability 19", "description": "A non-syndromic X-linked intellectual disability characterized by mild to moderate intellectual disability that has_material_basis_in hemizygous or heterozygous mutation in the RPS6KA3 gene on chromosome Xp22.12.", "url": "https://disease-ontology.org/term/DOID:0112019", "evidence": [ { "id": "0112019", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112019" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:2018", "name": "hyperinsulinism", "description": "", "url": "https://disease-ontology.org/term/DOID:2018", "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3783", "name": "Coffin-Lowry syndrome", "description": "A syndrome that is characterized by skeletal malformations, growth retardation, hearing deficit, paroxysmal movement disorders, and cognitive impairment in affected males and some carrier females, and has_material_basis_in mutation in the RSK2 gene on chromosome Xp22.", "url": "https://disease-ontology.org/term/DOID:3783", "evidence": [ { "id": "3783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3783" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 }, { "disease_id": "DOID:898", "name": "autosomal dominant polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal dominant fashion.", "url": "https://disease-ontology.org/term/DOID:898", "evidence": [ { "id": "898", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:898" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" } ], "pmid": "" } ], "biological_process": [ { "name": "protein autophosphorylation", "id": "GO:0046777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" } ], "pmid": "" }, { "name": "peptidyl-serine phosphorylation", "id": "GO:0018105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018105", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" } ], "pmid": "" }, { "name": "TORC1 signaling", "id": "GO:0038202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038202", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38070-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Thr107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Tyr320", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Ser321", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" }, { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Thr490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "501", "end_pos": "501", "site_lbl": "Ser501", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "505", "end_pos": "505", "site_lbl": "Ser505", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "513", "end_pos": "513", "site_lbl": "Ser513", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "25767889", "url": "https://glygen.org/publication/PubMed/25767889" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "517", "end_pos": "517", "site_lbl": "Ser517", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "519", "end_pos": "519", "site_lbl": "Ser519", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Thr82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38070", "url": "https://www.uniprot.org/uniprotkb/P38070" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38070-1", "start_pos": "94", "end_pos": "94", "site_lbl": "Ser94", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000232", "url": "https://www.yeastgenome.org/locus/S000000232" }, { "database": "iPTMnet", "id": "P38070", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38070" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P38070-1" }, { "uniprot_canonical_ac": "P38071-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38071", "url": "https://www.uniprot.org/uniprotkb/P38071" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 380, "chemical_mass": 42067.0, "gene_names": "ETR1;ETR1;MRF1';MRF1;YBR0310", "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "disease": [ { "disease_id": "DOID:0081419", "name": "childhood-onset dystonia with optic atrophy and basal ganglia abnormalities", "description": "A dystonia that is characterized by characterized by onset of involuntary movements in the first decade of life and that has_material_basis_in homozygous or compound heterozygous mutation in the MECR gene on chromosome 1p35. Optic atrophy develops around the same time or slightly later.", "url": "https://disease-ontology.org/term/DOID:0081419", "evidence": [ { "id": "0081419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081419" } ], "weight": 0.0 }, { "disease_id": "DOID:0111756", "name": "Leber hereditary optic neuropathy with demyelinating disease of CNS", "description": "A Leber plus disease characterized by Leber hereditary optic neuropathy and demyelination in the central nervous system.", "url": "https://disease-ontology.org/term/DOID:0111756", "evidence": [ { "id": "0111756", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111756" } ], "weight": 0.0 }, { "disease_id": "DOID:5723", "name": "optic atrophy", "description": "An optic nerve disease that is characterized the death of the retinal ganglion cell axons that comprise the optic nerve.", "url": "https://disease-ontology.org/term/DOID:5723", "evidence": [ { "id": "5723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5723" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P38071", "url": "https://www.uniprot.org/uniprotkb/P38071" } ], "pmid": "" }, { "name": "enoyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0141148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141148", "evidence": [ { "database": "UniProtKB", "id": "P38071", "url": "https://www.uniprot.org/uniprotkb/P38071" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P38071", "url": "https://www.uniprot.org/uniprotkb/P38071" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P38071", "url": "https://www.uniprot.org/uniprotkb/P38071" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "P38071", "url": "https://www.uniprot.org/uniprotkb/P38071" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "P38071", "url": "https://www.uniprot.org/uniprotkb/P38071" } ], "pmid": "" }, { "name": "aerobic respiration", "id": "GO:0009060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009060", "evidence": [ { "database": "UniProtKB", "id": "P38071", "url": "https://www.uniprot.org/uniprotkb/P38071" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38071-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38071" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000230", "url": "https://www.yeastgenome.org/locus/S000000230" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38071-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000230", "url": "https://www.yeastgenome.org/locus/S000000230" }, { "database": "iPTMnet", "id": "P38071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38071" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38071-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000230", "url": "https://www.yeastgenome.org/locus/S000000230" }, { "database": "iPTMnet", "id": "P38071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38071" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38071-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000230", "url": "https://www.yeastgenome.org/locus/S000000230" }, { "database": "iPTMnet", "id": "P38071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38071" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38071-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Thr295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000230", "url": "https://www.yeastgenome.org/locus/S000000230" }, { "database": "iPTMnet", "id": "P38071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38071" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38071-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Ser296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000230", "url": "https://www.yeastgenome.org/locus/S000000230" }, { "database": "iPTMnet", "id": "P38071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38071" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38071-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Ser339", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38071", "url": "https://www.uniprot.org/uniprotkb/P38071" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38071" }, { "database": "SGD", "id": "S000000230", "url": "https://www.yeastgenome.org/locus/S000000230" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38071-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Thr43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000230", "url": "https://www.yeastgenome.org/locus/S000000230" }, { "database": "iPTMnet", "id": "P38071", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38071" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38071-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Tyr73", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "N", "comment": "0.1% of catalytic activity. No specific ARS1 binding.", "evidence": [ { "database": "UniProtKB", "id": "P38071", "url": "https://www.uniprot.org/uniprotkb/P38071" }, { "database": "PubMed", "id": "12614607", "url": "https://glygen.org/publication/PubMed/12614607" } ] } ] } ], "record_id": "P38071-1" }, { "uniprot_canonical_ac": "P38075-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38075", "url": "https://www.uniprot.org/uniprotkb/P38075" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 228, "chemical_mass": 26908.0, "gene_names": "PDX3;PDX3;YBR0321", "protein_name": "Pyridoxamine 5'-phosphate oxidase", "disease": [ { "disease_id": "DOID:0111329", "name": "pyridoxamine 5'-phosphate oxidase deficiency", "description": "A vitamin metabolic disorder characterized by vitamin B6 deficienc resulting in neonatal-onset of severe seizures that can be controlled with pyridoxal 5'-phosphate treatment that has_material_basis_in homozygous or compound heterozygous mutation in PNPO on 17q21.32.", "url": "https://disease-ontology.org/term/DOID:0111329", "evidence": [ { "id": "0111329", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111329" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "P38075", "url": "https://www.uniprot.org/uniprotkb/P38075" } ], "pmid": "" } ], "molecular_function": [ { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "P38075", "url": "https://www.uniprot.org/uniprotkb/P38075" } ], "pmid": "" }, { "name": "pyridoxamine phosphate oxidase activity", "id": "GO:0004733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004733", "evidence": [ { "database": "UniProtKB", "id": "P38075", "url": "https://www.uniprot.org/uniprotkb/P38075" } ], "pmid": "" } ], "biological_process": [ { "name": "pyridoxine biosynthetic process", "id": "GO:0008615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008615", "evidence": [ { "database": "UniProtKB", "id": "P38075", "url": "https://www.uniprot.org/uniprotkb/P38075" } ], "pmid": "" }, { "name": "pyridoxal 5'-phosphate salvage", "id": "GO:0009443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009443", "evidence": [ { "database": "UniProtKB", "id": "P38075", "url": "https://www.uniprot.org/uniprotkb/P38075" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38075-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Ser144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000239", "url": "https://www.yeastgenome.org/locus/S000000239" }, { "database": "iPTMnet", "id": "P38075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38075" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38075-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000239", "url": "https://www.yeastgenome.org/locus/S000000239" }, { "database": "iPTMnet", "id": "P38075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38075" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38075-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Ser154", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000239", "url": "https://www.yeastgenome.org/locus/S000000239" }, { "database": "iPTMnet", "id": "P38075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38075" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38075-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Thr216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000239", "url": "https://www.yeastgenome.org/locus/S000000239" }, { "database": "iPTMnet", "id": "P38075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38075" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38075-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000239", "url": "https://www.yeastgenome.org/locus/S000000239" }, { "database": "iPTMnet", "id": "P38075", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38075" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38075-1" }, { "uniprot_canonical_ac": "P38077-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38077", "url": "https://www.uniprot.org/uniprotkb/P38077" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 311, "chemical_mass": 34351.0, "gene_names": "ATP3;ATP3a;ATP3b;ATP3;YBR0408", "protein_name": "ATP synthase subunit gamma, mitochondrial", "disease": [ { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P38077", "url": "https://www.uniprot.org/uniprotkb/P38077" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P38077", "url": "https://www.uniprot.org/uniprotkb/P38077" } ], "pmid": "" }, { "name": "proton-transporting ATP synthase complex", "id": "GO:0045259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045259", "evidence": [ { "database": "UniProtKB", "id": "P38077", "url": "https://www.uniprot.org/uniprotkb/P38077" } ], "pmid": "" } ], "biological_process": [ { "name": "proton motive force-driven ATP synthesis", "id": "GO:0015986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015986", "evidence": [ { "database": "UniProtKB", "id": "P38077", "url": "https://www.uniprot.org/uniprotkb/P38077" } ], "pmid": "" } ], "molecular_function": [ { "name": "proton-transporting ATP synthase activity, rotational mechanism", "id": "GO:0046933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046933", "evidence": [ { "database": "UniProtKB", "id": "P38077", "url": "https://www.uniprot.org/uniprotkb/P38077" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38077-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Ser122", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000243", "url": "https://www.yeastgenome.org/locus/S000000243" }, { "database": "iPTMnet", "id": "P38077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38077-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000243", "url": "https://www.yeastgenome.org/locus/S000000243" }, { "database": "iPTMnet", "id": "P38077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38077" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P38077-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Ser185", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000243", "url": "https://www.yeastgenome.org/locus/S000000243" }, { "database": "iPTMnet", "id": "P38077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38077" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P38077-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Ser224", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000243", "url": "https://www.yeastgenome.org/locus/S000000243" }, { "database": "iPTMnet", "id": "P38077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38077-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000243", "url": "https://www.yeastgenome.org/locus/S000000243" }, { "database": "iPTMnet", "id": "P38077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38077-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000243", "url": "https://www.yeastgenome.org/locus/S000000243" }, { "database": "iPTMnet", "id": "P38077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38077" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38077-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000243", "url": "https://www.yeastgenome.org/locus/S000000243" }, { "database": "iPTMnet", "id": "P38077", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38077" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38077-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ala273", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "V", "comment": "Lower activity.", "evidence": [ { "database": "UniProtKB", "id": "P38077", "url": "https://www.uniprot.org/uniprotkb/P38077" }, { "database": "PubMed", "id": "7929329", "url": "https://glygen.org/publication/PubMed/7929329" } ] } ] }, { "uniprot_canonical_ac": "P38077-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Thr297", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "In ATP3-5; dominant suppressor of the slow-growth phenotype of yme1 strains lacking mitochondrial DNA.", "evidence": [ { "database": "UniProtKB", "id": "P38077", "url": "https://www.uniprot.org/uniprotkb/P38077" }, { "database": "PubMed", "id": "7498726", "url": "https://glygen.org/publication/PubMed/7498726" } ] } ] }, { "uniprot_canonical_ac": "P38077-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Ile303", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "T", "comment": "In ATP3-1; dominant suppressor of the slow-growth phenotype of yme1 strains lacking mitochondrial DNA.", "evidence": [ { "database": "UniProtKB", "id": "P38077", "url": "https://www.uniprot.org/uniprotkb/P38077" }, { "database": "PubMed", "id": "7498726", "url": "https://glygen.org/publication/PubMed/7498726" } ] } ] } ], "record_id": "P38077-1" }, { "uniprot_canonical_ac": "P38080-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1108, "chemical_mass": 123989.0, "gene_names": "AKL1;AKL1;YBR0519", "protein_name": "Serine/threonine-protein kinase AKL1", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" }, { "name": "prospore membrane", "id": "GO:0005628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005628", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" }, { "name": "actin cortical patch assembly", "id": "GO:0000147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000147", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" }, { "name": "negative regulation of clathrin-dependent endocytosis", "id": "GO:1900186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900186", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38080-1", "start_pos": "1001", "end_pos": "1001", "site_lbl": "Ser1001", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1001, "start_aa": "Ser", "end_pos": 1001, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1001", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1048", "end_pos": "1048", "site_lbl": "Ser1048", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1048, "start_aa": "Ser", "end_pos": 1048, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1048", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "12872131", "url": "https://glygen.org/publication/PubMed/12872131" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1050", "end_pos": "1050", "site_lbl": "Ser1050", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1050, "start_aa": "Ser", "end_pos": 1050, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1050", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1051", "end_pos": "1051", "site_lbl": "Ser1051", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1051, "start_aa": "Ser", "end_pos": 1051, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1051", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "12872131", "url": "https://glygen.org/publication/PubMed/12872131" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1055", "end_pos": "1055", "site_lbl": "Ser1055", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1055, "start_aa": "Ser", "end_pos": 1055, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1055", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1057", "end_pos": "1057", "site_lbl": "Ser1057", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1057, "start_aa": "Ser", "end_pos": 1057, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1057", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1060", "end_pos": "1060", "site_lbl": "Ser1060", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1060, "start_aa": "Ser", "end_pos": 1060, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1060", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1085", "end_pos": "1085", "site_lbl": "Ser1085", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1085, "start_aa": "Ser", "end_pos": 1085, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1085", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1086", "end_pos": "1086", "site_lbl": "Ser1086", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1086, "start_aa": "Ser", "end_pos": 1086, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1086", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1088", "end_pos": "1088", "site_lbl": "Ser1088", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1088, "start_aa": "Ser", "end_pos": 1088, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1088", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1089", "end_pos": "1089", "site_lbl": "Ser1089", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1089, "start_aa": "Ser", "end_pos": 1089, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1089", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1090", "end_pos": "1090", "site_lbl": "Ser1090", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1090, "start_aa": "Ser", "end_pos": 1090, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1090", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1093", "end_pos": "1093", "site_lbl": "Ser1093", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1093, "start_aa": "Ser", "end_pos": 1093, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1093", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "997", "end_pos": "997", "site_lbl": "Ser997", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 997, "start_aa": "Ser", "end_pos": 997, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser997", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38080", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38080" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1002", "end_pos": "1002", "site_lbl": "Thr1002", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1011", "end_pos": "1011", "site_lbl": "Ser1011", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1012", "end_pos": "1012", "site_lbl": "Thr1012", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1053", "end_pos": "1053", "site_lbl": "Thr1053", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1072", "end_pos": "1072", "site_lbl": "Ser1072", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "28069741", "url": "https://glygen.org/publication/PubMed/28069741" }, { "database": "PubMed", "id": "29895620", "url": "https://glygen.org/publication/PubMed/29895620" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1099", "end_pos": "1099", "site_lbl": "Ser1099", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "1106", "end_pos": "1106", "site_lbl": "Ser1106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Ser403", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Ser407", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "422", "end_pos": "422", "site_lbl": "Ser422", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Ser430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Ser434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Ser435", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "446", "end_pos": "446", "site_lbl": "Thr446", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Ser458", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "465", "end_pos": "465", "site_lbl": "Ser465", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Thr471", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Ser479", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "485", "end_pos": "485", "site_lbl": "Thr485", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "486", "end_pos": "486", "site_lbl": "Tyr486", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Ser495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "496", "end_pos": "496", "site_lbl": "Ser496", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "501", "end_pos": "501", "site_lbl": "Ser501", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Ser504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "509", "end_pos": "509", "site_lbl": "Thr509", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "511", "end_pos": "511", "site_lbl": "Ser511", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Ser518", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "520", "end_pos": "520", "site_lbl": "Ser520", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "521", "end_pos": "521", "site_lbl": "Ser521", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Ser523", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "524", "end_pos": "524", "site_lbl": "Ser524", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Ser531", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "532", "end_pos": "532", "site_lbl": "Thr532", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "533", "end_pos": "533", "site_lbl": "Ser533", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Thr538", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "541", "end_pos": "541", "site_lbl": "Ser541", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "561", "end_pos": "561", "site_lbl": "Ser561", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "572", "end_pos": "572", "site_lbl": "Tyr572", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "574", "end_pos": "574", "site_lbl": "Ser574", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Thr575", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "603", "end_pos": "603", "site_lbl": "Thr603", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "605", "end_pos": "605", "site_lbl": "Thr605", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "637", "end_pos": "637", "site_lbl": "Ser637", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "763", "end_pos": "763", "site_lbl": "Thr763", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "801", "end_pos": "801", "site_lbl": "Ser801", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "815", "end_pos": "815", "site_lbl": "Thr815", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "829", "end_pos": "829", "site_lbl": "Ser829", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "846", "end_pos": "846", "site_lbl": "Ser846", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "853", "end_pos": "853", "site_lbl": "Ser853", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "863", "end_pos": "863", "site_lbl": "Ser863", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "865", "end_pos": "865", "site_lbl": "Ser865", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "867", "end_pos": "867", "site_lbl": "Ser867", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "879", "end_pos": "879", "site_lbl": "Ser879", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "884", "end_pos": "884", "site_lbl": "Ser884", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "891", "end_pos": "891", "site_lbl": "Ser891", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "904", "end_pos": "904", "site_lbl": "Ser904", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "950", "end_pos": "950", "site_lbl": "Ser950", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "953", "end_pos": "953", "site_lbl": "Ser953", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "960", "end_pos": "960", "site_lbl": "Ser960", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38080", "url": "https://www.uniprot.org/uniprotkb/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "28069741", "url": "https://glygen.org/publication/PubMed/28069741" }, { "database": "PubMed", "id": "29895620", "url": "https://glygen.org/publication/PubMed/29895620" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "971", "end_pos": "971", "site_lbl": "Ser971", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "972", "end_pos": "972", "site_lbl": "Ser972", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "974", "end_pos": "974", "site_lbl": "Thr974", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38080-1", "start_pos": "985", "end_pos": "985", "site_lbl": "Ser985", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38080" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000263", "url": "https://www.yeastgenome.org/locus/S000000263" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P38080-1" }, { "uniprot_canonical_ac": "P38084-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 609, "chemical_mass": 67769.0, "gene_names": "BAP2;BAP2;YBR0629", "protein_name": "Leu/Val/Ile amino-acid permease", "disease": [ { "disease_id": "DOID:0110374", "name": "retinitis pigmentosa 68", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the SLC7A14 gene on chromosome 3q26.", "url": "https://disease-ontology.org/term/DOID:0110374", "evidence": [ { "id": "0110374", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110374" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 }, { "disease_id": "DOID:1432", "name": "blindness", "description": "An eye disease characterized by a lack or loss of vision.", "url": "https://disease-ontology.org/term/DOID:1432", "evidence": [ { "id": "1432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1432" } ], "weight": 0.0 } ], "biological_process": [ { "name": "L-leucine import across plasma membrane", "id": "GO:1903801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903801", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" } ], "pmid": "" }, { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" } ], "pmid": "" } ], "molecular_function": [ { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" } ], "pmid": "" }, { "name": "L-phenylalanine transmembrane transporter activity", "id": "GO:0015192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015192", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38084-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Thr111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Thr15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Ser21", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Ser35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Ser599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38084", "url": "https://www.uniprot.org/uniprotkb/P38084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Thr86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38084-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000272", "url": "https://www.yeastgenome.org/locus/S000000272" }, { "database": "iPTMnet", "id": "P38084", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38084" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38084-1" }, { "uniprot_canonical_ac": "P38085-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 619, "chemical_mass": 68758.0, "gene_names": "TAT1;TAP1;TAT1;VAP1;YBR0710", "protein_name": "Valine/tyrosine/tryptophan amino-acid permease 1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" }, { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" }, { "name": "tryptophan transport", "id": "GO:0015827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015827", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" }, { "name": "tyrosine transport", "id": "GO:0015828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015828", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" } ], "molecular_function": [ { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" }, { "name": "low-affinity tryptophan transmembrane transporter activity", "id": "GO:0022893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022893", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38085-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "17", "end_pos": "17", "site_lbl": "Tyr17", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Thr35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Thr37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Thr47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Ser577", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "579", "end_pos": "579", "site_lbl": "Thr579", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "593", "end_pos": "593", "site_lbl": "Tyr593", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Ser596", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "598", "end_pos": "598", "site_lbl": "Ser598", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Ser599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "605", "end_pos": "605", "site_lbl": "Ser605", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Ser80", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Ser84", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38085", "url": "https://www.uniprot.org/uniprotkb/P38085" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000273", "url": "https://www.yeastgenome.org/locus/S000000273" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38085-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Thr91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38085" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] } ], "record_id": "P38085-1" }, { "uniprot_canonical_ac": "P38086-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 958, "chemical_mass": 107946.0, "gene_names": "RDH54;RDH54;TID1;YBR0715", "protein_name": "DNA repair and recombination protein RDH54", "disease": [ { "disease_id": "DOID:0060060", "name": "non-Hodgkin lymphoma", "description": "A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma.", "url": "https://disease-ontology.org/term/DOID:0060060", "evidence": [ { "id": "0060060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060060" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "DNA translocase activity", "id": "GO:0015616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015616", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "DNA geometric change", "id": "GO:0032392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032392", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "heteroduplex formation", "id": "GO:0030491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030491", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" }, { "name": "meiotic sister chromatid segregation", "id": "GO:0045144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045144", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38086-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Ser124", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" }, { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Ser199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" }, { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Thr206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" }, { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" }, { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" }, { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "653", "end_pos": "653", "site_lbl": "Ser653", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" }, { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Ser85", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" }, { "database": "PubMed", "id": "19917248", "url": "https://glygen.org/publication/PubMed/19917248" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "880", "end_pos": "880", "site_lbl": "Ser880", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "885", "end_pos": "885", "site_lbl": "Thr885", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" }, { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "886", "end_pos": "886", "site_lbl": "Ser886", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" }, { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000277", "url": "https://www.yeastgenome.org/locus/S000000277" }, { "database": "iPTMnet", "id": "P38086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38086" }, { "database": "PubMed", "id": "19917248", "url": "https://glygen.org/publication/PubMed/19917248" } ] } ] }, { "uniprot_canonical_ac": "P38086-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Lys352", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "1%-2% of the ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P38086", "url": "https://www.uniprot.org/uniprotkb/P38086" }, { "database": "PubMed", "id": "10970884", "url": "https://glygen.org/publication/PubMed/10970884" } ] } ] } ], "record_id": "P38086-1" }, { "uniprot_canonical_ac": "P38088-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 690, "chemical_mass": 78184.0, "gene_names": "GRS1;GRS1;YBR0917", "protein_name": "Glycine--tRNA ligase 1, mitochondrial", "disease": [ { "disease_id": "DOID:0050539", "name": "Charcot-Marie-Tooth disease type 2", "description": "A Charcot-Marie-Tooth disease characterized by abnormalities in the axon of the peripheral nerve cell.", "url": "https://disease-ontology.org/term/DOID:0050539", "evidence": [ { "id": "0050539", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050539" } ], "weight": 0.0 }, { "disease_id": "DOID:0110164", "name": "Charcot-Marie-Tooth disease type 2D", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in mutation in the GARS1 gene.", "url": "https://disease-ontology.org/term/DOID:0110164", "evidence": [ { "id": "0110164", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110164" } ], "weight": 0.0 }, { "disease_id": "DOID:0111203", "name": "autosomal dominant distal hereditary motor neuronopathy 5", "description": "An autosomal dominant distal hereditary motor neuronopathy that is characterized by onset of distal muscle weakness and atrophy predominantly affecting the upper limbs in the first few decades of life and that has_material_basis_in heterozygous mutation in the GARS gene on chromosome 7p14.", "url": "https://disease-ontology.org/term/DOID:0111203", "evidence": [ { "id": "0111203", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111203" } ], "weight": 0.0 }, { "disease_id": "DOID:10595", "name": "Charcot-Marie-Tooth disease", "description": "A neuromuscular disease that is characterized by a slowly progressive degeneration of the muscles of the foot, lower leg, hand and forearm.", "url": "https://disease-ontology.org/term/DOID:10595", "evidence": [ { "id": "10595", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10595" } ], "weight": 0.0 }, { "disease_id": "DOID:12377", "name": "spinal muscular atrophy", "description": "A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy.", "url": "https://disease-ontology.org/term/DOID:12377", "evidence": [ { "id": "12377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12377" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "sequence-specific mRNA binding", "id": "GO:1990825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990825", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" }, { "name": "glycine-tRNA ligase activity", "id": "GO:0004820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004820", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" }, { "name": "ATP:ATP adenylyltransferase activity", "id": "GO:0141192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141192", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" } ], "biological_process": [ { "name": "diadenosine tetraphosphate biosynthetic process", "id": "GO:0015966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015966", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" }, { "name": "DNA-templated transcription termination", "id": "GO:0006353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006353", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" }, { "name": "mitochondrial glycyl-tRNA aminoacylation", "id": "GO:0070150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070150", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" }, { "name": "glycyl-tRNA aminoacylation", "id": "GO:0006426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006426", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38088-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Thr223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Ser226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Thr271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Ser277", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Ser287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Ser351", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "378", "end_pos": "378", "site_lbl": "Ser378", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Ser426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "476", "end_pos": "476", "site_lbl": "Ser476", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "482", "end_pos": "482", "site_lbl": "Ser482", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "528", "end_pos": "528", "site_lbl": "Ser528", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "558", "end_pos": "558", "site_lbl": "Ser558", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "561", "end_pos": "561", "site_lbl": "Ser561", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "608", "end_pos": "608", "site_lbl": "Ser608", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Tyr613", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "636", "end_pos": "636", "site_lbl": "Ser636", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "651", "end_pos": "651", "site_lbl": "Ser651", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "689", "end_pos": "689", "site_lbl": "Thr689", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38088", "url": "https://www.uniprot.org/uniprotkb/P38088" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38088-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000325", "url": "https://www.yeastgenome.org/locus/S000000325" }, { "database": "iPTMnet", "id": "P38088", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38088" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38088-1" }, { "uniprot_canonical_ac": "P38090-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38090", "url": "https://www.uniprot.org/uniprotkb/P38090" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 596, "chemical_mass": 67262.0, "gene_names": "AGP2;AGP2;YBR1007", "protein_name": "General amino acid permease AGP2", "disease": [ { "disease_id": "DOID:0110374", "name": "retinitis pigmentosa 68", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the SLC7A14 gene on chromosome 3q26.", "url": "https://disease-ontology.org/term/DOID:0110374", "evidence": [ { "id": "0110374", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110374" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P38090", "url": "https://www.uniprot.org/uniprotkb/P38090" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38090", "url": "https://www.uniprot.org/uniprotkb/P38090" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P38090", "url": "https://www.uniprot.org/uniprotkb/P38090" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P38090", "url": "https://www.uniprot.org/uniprotkb/P38090" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P38090", "url": "https://www.uniprot.org/uniprotkb/P38090" } ], "pmid": "" } ], "molecular_function": [ { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "P38090", "url": "https://www.uniprot.org/uniprotkb/P38090" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "P38090", "url": "https://www.uniprot.org/uniprotkb/P38090" } ], "pmid": "" }, { "name": "positive regulation of polyamine transmembrane transport", "id": "GO:1902269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902269", "evidence": [ { "database": "UniProtKB", "id": "P38090", "url": "https://www.uniprot.org/uniprotkb/P38090" } ], "pmid": "" }, { "name": "positive regulation of (R)-carnitine transmembrane transport", "id": "GO:1902274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902274", "evidence": [ { "database": "UniProtKB", "id": "P38090", "url": "https://www.uniprot.org/uniprotkb/P38090" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38090-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000336", "url": "https://www.yeastgenome.org/locus/S000000336" }, { "database": "iPTMnet", "id": "P38090", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38090" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38090-1" }, { "uniprot_canonical_ac": "P38109-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 508, "chemical_mass": 57639.0, "gene_names": "ATG42;ATG42;YBR1015", "protein_name": "Vacuolar serine-type carboxypeptidase ATG42", "disease": [ { "disease_id": "DOID:0061236", "name": "brain small vessel disease 6 with leukoencephalopathy", "description": "A brain small vessel disease characterized by central nervous system manifestations, including migraine, stroke, transient movement disorders, gait disturbance, and progressive cognitive decline that has_material_basis_in heterozygous mutation in the CTSA gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0061236", "evidence": [ { "id": "0061236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061236" } ], "weight": 0.0 }, { "disease_id": "DOID:0080540", "name": "galactosialidosis", "description": "A lysosomal storage disease that is characterized by combined deficiency of beta-galactosidase and neuraminidase that has_material_basis_in homozygous or compound heterozygous mutation in the CTSA gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0080540", "evidence": [ { "id": "0080540", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080540" } ], "weight": 0.0 }, { "disease_id": "DOID:3211", "name": "lysosomal storage disease", "description": "An inherited metabolic disorder that involve an abnormal accumulation of substances inside the lysosome resulting from defects in lysosomal function.", "url": "https://disease-ontology.org/term/DOID:3211", "evidence": [ { "id": "3211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3211" } ], "weight": 0.0 } ], "biological_process": [ { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" } ], "pmid": "" }, { "name": "zymogen activation", "id": "GO:0031638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031638", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" } ], "pmid": "" }, { "name": "phytochelatin biosynthetic process", "id": "GO:0046938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046938", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" } ], "pmid": "" } ], "molecular_function": [ { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" } ], "pmid": "" }, { "name": "serine-type carboxypeptidase activity", "id": "GO:0004185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004185", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" } ], "pmid": "" } ], "cellular_component": [ { "name": "vacuolar lumen", "id": "GO:0005775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005775", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" } ], "pmid": "" }, { "name": "fungal-type vacuole lumen", "id": "GO:0000328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000328", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38109-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Asn163", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 163, "start_aa": "Asn", "end_pos": 163, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn163", "evidence": [ { "id": "P38109", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38109#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" }, { "id": "29514932", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29514932" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Reduces the glycolation level.", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" }, { "database": "PubMed", "id": "29514932", "url": "https://glygen.org/publication/PubMed/29514932" } ] } ] }, { "uniprot_canonical_ac": "P38109-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Asn242", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 242, "start_aa": "Asn", "end_pos": 242, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn242", "evidence": [ { "id": "P38109", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38109#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" }, { "id": "29514932", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29514932" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Reduces the glycolation level.", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" }, { "database": "PubMed", "id": "29514932", "url": "https://glygen.org/publication/PubMed/29514932" } ] } ] }, { "uniprot_canonical_ac": "P38109-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Asn339", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 339, "start_aa": "Asn", "end_pos": 339, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn339", "evidence": [ { "id": "P38109", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38109#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P38109-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Asn371", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 371, "start_aa": "Asn", "end_pos": 371, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn371", "evidence": [ { "id": "P38109", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38109#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "P38109-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Leads to partial block in enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" }, { "database": "PubMed", "id": "29514932", "url": "https://glygen.org/publication/PubMed/29514932" } ] } ] }, { "uniprot_canonical_ac": "P38109-1", "start_pos": "415", "end_pos": "415", "site_lbl": "Asp415", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Leads to partial block in enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" }, { "database": "PubMed", "id": "29514932", "url": "https://glygen.org/publication/PubMed/29514932" } ] } ] }, { "uniprot_canonical_ac": "P38109-1", "start_pos": "474", "end_pos": "474", "site_lbl": "His474", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Leads to partial block in enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "P38109", "url": "https://www.uniprot.org/uniprotkb/P38109" }, { "database": "PubMed", "id": "29514932", "url": "https://glygen.org/publication/PubMed/29514932" } ] } ] } ], "record_id": "P38109-1" }, { "uniprot_canonical_ac": "P38110-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 2787, "chemical_mass": 321524.0, "gene_names": "TEL1;TEL1;YBL0706", "protein_name": "Serine/threonine-protein kinase TEL1", "disease": [ { "disease_id": "DOID:0050671", "name": "female breast cancer", "description": "A breast cancer that develops from breast tissue in females.", "url": "https://disease-ontology.org/term/DOID:0050671", "evidence": [ { "id": "0050671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050671" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0060058", "name": "lymphoma", "description": "A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs.", "url": "https://disease-ontology.org/term/DOID:0060058", "evidence": [ { "id": "0060058", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060058" } ], "weight": 0.0 }, { "disease_id": "DOID:0060071", "name": "pre-malignant neoplasm", "description": "A disease of cellular proliferation that results in abnormal growths in the body, which do not invade or destroy the surrounding tissue but, given enough time, will transform into a cancer.", "url": "https://disease-ontology.org/term/DOID:0060071", "evidence": [ { "id": "0060071", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060071" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1240", "name": "leukemia", "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.", "url": "https://disease-ontology.org/term/DOID:1240", "evidence": [ { "id": "1240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1240" } ], "weight": 0.0 }, { "disease_id": "DOID:12704", "name": "ataxia telangiectasia", "description": "An autosomal recessive cerebellar ataxia that is characterized by cerebellar ataxia, telangiectases, immune defects, and a predisposition to malignancy and that has_material_basis_in homozygous or compound heterozygous mutation in the ATM gene on chromosome 11q22.", "url": "https://disease-ontology.org/term/DOID:12704", "evidence": [ { "id": "12704", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12704" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:14566", "name": "disease of cellular proliferation", "description": "A disease that is characterized by abnormally rapid cell division.", "url": "https://disease-ontology.org/term/DOID:14566", "evidence": [ { "id": "14566", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14566" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3969", "name": "papillary thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer and arises from the follicular cells of the thyroid gland.", "url": "https://disease-ontology.org/term/DOID:3969", "evidence": [ { "id": "3969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3969" } ], "weight": 0.0 }, { "disease_id": "DOID:5223", "name": "infertility", "description": "", "url": "https://disease-ontology.org/term/DOID:5223", "evidence": [ { "id": "5223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5223" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:8634", "name": "prostate carcinoma in situ", "description": "An in situ carcinoma that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:8634", "evidence": [ { "id": "8634", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8634" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 }, { "disease_id": "DOID:9655", "name": "oral mucosa leukoplakia", "description": "A mouth disease that is characterized by a white patch or plaque that develops in the oral cavity and is strongly associated with smoking.", "url": "https://disease-ontology.org/term/DOID:9655", "evidence": [ { "id": "9655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9655" } ], "weight": 0.0 }, { "disease_id": "DOID:9669", "name": "senile cataract", "description": "A cataract that is characterized by thickening and loss of transparency of the lens with age progression, caused by a multifactorial etiology related to aging.", "url": "https://disease-ontology.org/term/DOID:9669", "evidence": [ { "id": "9669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9669" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "signal transduction in response to DNA damage", "id": "GO:0042770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042770", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38110-1", "start_pos": "1804", "end_pos": "1804", "site_lbl": "Thr1804", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000184", "url": "https://www.yeastgenome.org/locus/S000000184" }, { "database": "iPTMnet", "id": "P38110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38110" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38110-1", "start_pos": "689", "end_pos": "689", "site_lbl": "Ser689", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38110" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38110-1", "start_pos": "690", "end_pos": "690", "site_lbl": "Ser690", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38110", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38110" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38110-1", "start_pos": "1319", "end_pos": "1319", "site_lbl": "Glu1319", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "In TEL1-11; short telomere phenotype and impairs DNA-damage checkpoint function at 37 degrees Celsius.", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" }, { "database": "PubMed", "id": "16228207", "url": "https://glygen.org/publication/PubMed/16228207" } ] } ] }, { "uniprot_canonical_ac": "P38110-1", "start_pos": "2616", "end_pos": "2616", "site_lbl": "Asn2616", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "K", "comment": "Short telomere phenotype in vivo and impairs kinase activity in vitro; when associated with D-2611-2612-A and E-2631.", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" }, { "database": "PubMed", "id": "11095737", "url": "https://glygen.org/publication/PubMed/11095737" }, { "database": "PubMed", "id": "7671310", "url": "https://glygen.org/publication/PubMed/7671310" } ] } ] }, { "uniprot_canonical_ac": "P38110-1", "start_pos": "2631", "end_pos": "2631", "site_lbl": "Asp2631", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "Short telomere phenotype in vivo and impairs kinase activity in vitro; when associated with D-2611-2612-A and K-2616.", "evidence": [ { "database": "UniProtKB", "id": "P38110", "url": "https://www.uniprot.org/uniprotkb/P38110" }, { "database": "PubMed", "id": "11095737", "url": "https://glygen.org/publication/PubMed/11095737" }, { "database": "PubMed", "id": "7671310", "url": "https://glygen.org/publication/PubMed/7671310" } ] } ] } ], "record_id": "P38110-1" }, { "uniprot_canonical_ac": "P38111-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 2368, "chemical_mass": 273342.0, "gene_names": "MEC1;ESR1;MEC1;RAD31;SAD3;YBR1012", "protein_name": "Serine/threonine-protein kinase MEC1", "disease": [ { "disease_id": "DOID:0050569", "name": "Seckel syndrome", "description": "A syndrome characterized by intrauterine growth retardation and postnatal dwarfism with microcephaly and intellectual disability.", "url": "https://disease-ontology.org/term/DOID:0050569", "evidence": [ { "id": "0050569", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050569" } ], "weight": 0.0 }, { "disease_id": "DOID:0060060", "name": "non-Hodgkin lymphoma", "description": "A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma.", "url": "https://disease-ontology.org/term/DOID:0060060", "evidence": [ { "id": "0060060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060060" } ], "weight": 0.0 }, { "disease_id": "DOID:0070007", "name": "Seckel syndrome 1", "description": "A Seckel syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the ATR gene on chromosome 3q23.", "url": "https://disease-ontology.org/term/DOID:0070007", "evidence": [ { "id": "0070007", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070007" } ], "weight": 0.0 }, { "disease_id": "DOID:0080202", "name": "adenoid cystic carcinoma", "description": "An adenocarcinoma that is characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells.", "url": "https://disease-ontology.org/term/DOID:0080202", "evidence": [ { "id": "0080202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080202" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12704", "name": "ataxia telangiectasia", "description": "An autosomal recessive cerebellar ataxia that is characterized by cerebellar ataxia, telangiectases, immune defects, and a predisposition to malignancy and that has_material_basis_in homozygous or compound heterozygous mutation in the ATM gene on chromosome 11q22.", "url": "https://disease-ontology.org/term/DOID:12704", "evidence": [ { "id": "12704", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12704" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "signal transduction in response to DNA damage", "id": "GO:0042770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042770", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated DNA replication", "id": "GO:2000105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000105", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "telomere maintenance via recombination", "id": "GO:0000722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000722", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" }, { "name": "regulation of double-strand break repair", "id": "GO:2000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000779", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38111-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Tyr117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000340", "url": "https://www.yeastgenome.org/locus/S000000340" }, { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "1964", "end_pos": "1964", "site_lbl": "Ser1964", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000340", "url": "https://www.yeastgenome.org/locus/S000000340" }, { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "31340146", "url": "https://glygen.org/publication/PubMed/31340146" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "1991", "end_pos": "1991", "site_lbl": "Ser1991", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000340", "url": "https://www.yeastgenome.org/locus/S000000340" }, { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "34569643", "url": "https://glygen.org/publication/PubMed/34569643" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "1994", "end_pos": "1994", "site_lbl": "Ser1994", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000340", "url": "https://www.yeastgenome.org/locus/S000000340" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Thr336", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "14595109", "url": "https://glygen.org/publication/PubMed/14595109" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Ser36", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000340", "url": "https://www.yeastgenome.org/locus/S000000340" }, { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "378", "end_pos": "378", "site_lbl": "Ser378", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "20061370", "url": "https://glygen.org/publication/PubMed/20061370" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000340", "url": "https://www.yeastgenome.org/locus/S000000340" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Ser38", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000340", "url": "https://www.yeastgenome.org/locus/S000000340" }, { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Thr73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000340", "url": "https://www.yeastgenome.org/locus/S000000340" }, { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "990", "end_pos": "990", "site_lbl": "Ser990", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000340", "url": "https://www.yeastgenome.org/locus/S000000340" }, { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "994", "end_pos": "994", "site_lbl": "Thr994", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000340", "url": "https://www.yeastgenome.org/locus/S000000340" }, { "database": "iPTMnet", "id": "P38111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38111" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "1179", "end_pos": "1179", "site_lbl": "Phe1179", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "S", "comment": "In MEC1-100; impairs both the G1/S and intra-S damage checkpoints but not the G2/M damage checkpoint; when associated with S-1700.", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" }, { "database": "PubMed", "id": "11359899", "url": "https://glygen.org/publication/PubMed/11359899" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "1700", "end_pos": "1700", "site_lbl": "Asn1700", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "S", "comment": "In MEC1-100; impairs both the G1/S and intra-S damage checkpoints but not the G2/M damage checkpoint; when associated with S-1179.", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" }, { "database": "PubMed", "id": "11359899", "url": "https://glygen.org/publication/PubMed/11359899" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "2224", "end_pos": "2224", "site_lbl": "Asp2224", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Impairs kinase activity; when associated with K-2229.", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" }, { "database": "PubMed", "id": "11359899", "url": "https://glygen.org/publication/PubMed/11359899" }, { "database": "PubMed", "id": "11095737", "url": "https://glygen.org/publication/PubMed/11095737" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "2229", "end_pos": "2229", "site_lbl": "Asn2229", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "K", "comment": "Impairs kinase activity; when associated with A-2224.", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" }, { "database": "PubMed", "id": "11095737", "url": "https://glygen.org/publication/PubMed/11095737" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "2243", "end_pos": "2243", "site_lbl": "Asp2243", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "Impairs kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" }, { "database": "PubMed", "id": "11359899", "url": "https://glygen.org/publication/PubMed/11359899" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Val225", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "G", "comment": "In MEC1-101; impairs both the G1/S and intra-S damage checkpoints but not the G2/M damage checkpoint; when associated with P-552 and S-781.", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" }, { "database": "PubMed", "id": "11359899", "url": "https://glygen.org/publication/PubMed/11359899" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "552", "end_pos": "552", "site_lbl": "Ser552", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "P", "comment": "In MEC1-101; impairs both the G1/S and intra-S damage checkpoints but not the G2/M damage checkpoint; when associated with S-225 and S-781.", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" }, { "database": "PubMed", "id": "11359899", "url": "https://glygen.org/publication/PubMed/11359899" } ] } ] }, { "uniprot_canonical_ac": "P38111-1", "start_pos": "781", "end_pos": "781", "site_lbl": "Leu781", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "In MEC1-101; impairs both the G1/S and intra-S damage checkpoints but not the G2/M damage checkpoint; when associated with S-225 and P-552.", "evidence": [ { "database": "UniProtKB", "id": "P38111", "url": "https://www.uniprot.org/uniprotkb/P38111" }, { "database": "PubMed", "id": "11359899", "url": "https://glygen.org/publication/PubMed/11359899" } ] } ] } ], "record_id": "P38111-1" }, { "uniprot_canonical_ac": "P38112-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 773, "chemical_mass": 87048.0, "gene_names": "MAK5;MAK5;YBR1119", "protein_name": "ATP-dependent RNA helicase MAK5", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000466", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38112-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Thr135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Tyr296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Ser436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Ser575", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "584", "end_pos": "584", "site_lbl": "Ser584", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "657", "end_pos": "657", "site_lbl": "Ser657", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "678", "end_pos": "678", "site_lbl": "Ser678", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Ser684", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "686", "end_pos": "686", "site_lbl": "Ser686", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "688", "end_pos": "688", "site_lbl": "Ser688", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Ser752", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Ser86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "93", "end_pos": "93", "site_lbl": "Ser93", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Ser97", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000346", "url": "https://www.yeastgenome.org/locus/S000000346" }, { "database": "iPTMnet", "id": "P38112", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38112" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38112-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Gly218", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Delays the appearance and decreases the level of 25S rRNA.", "evidence": [ { "database": "UniProtKB", "id": "P38112", "url": "https://www.uniprot.org/uniprotkb/P38112" }, { "database": "PubMed", "id": "13680366", "url": "https://glygen.org/publication/PubMed/13680366" } ] } ] } ], "record_id": "P38112-1" }, { "uniprot_canonical_ac": "P38115-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38115", "url": "https://www.uniprot.org/uniprotkb/P38115" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 344, "chemical_mass": 38884.0, "gene_names": "ARA1;ARA1;YBR1127", "protein_name": "D-arabinose dehydrogenase [NAD(P)+] heavy chain", "disease": [ { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:11612", "name": "polycystic ovary syndrome", "description": "An ovarian dysfunction that is characterized by hyperandrogenism, polycystic ovaries, hirsutism, oligomenorrhea or amenorrhea, anovulation and excessive body weight.", "url": "https://disease-ontology.org/term/DOID:11612", "evidence": [ { "id": "11612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11612" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:4500", "name": "hypokalemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4500", "evidence": [ { "id": "4500", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4500" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 }, { "disease_id": "DOID:9870", "name": "galactosemia", "description": "A carbohydrate metabolic disorder that involves a defect in galactose metabolism resulting in toxic levels of galactose 1-phosphate in various tissues.", "url": "https://disease-ontology.org/term/DOID:9870", "evidence": [ { "id": "9870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9870" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38115", "url": "https://www.uniprot.org/uniprotkb/P38115" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "P38115", "url": "https://www.uniprot.org/uniprotkb/P38115" } ], "pmid": "" }, { "name": "acetoin metabolic process", "id": "GO:0045149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045149", "evidence": [ { "database": "UniProtKB", "id": "P38115", "url": "https://www.uniprot.org/uniprotkb/P38115" } ], "pmid": "" } ], "molecular_function": [ { "name": "aldose reductase (NADPH) activity", "id": "GO:0004032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004032", "evidence": [ { "database": "UniProtKB", "id": "P38115", "url": "https://www.uniprot.org/uniprotkb/P38115" } ], "pmid": "" }, { "name": "D-arabinose 1-dehydrogenase [NAD(P)+] activity", "id": "GO:0045290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045290", "evidence": [ { "database": "UniProtKB", "id": "P38115", "url": "https://www.uniprot.org/uniprotkb/P38115" } ], "pmid": "" }, { "name": "D-arabinose 1-dehydrogenase (NAD+) activity", "id": "GO:0047816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047816", "evidence": [ { "database": "UniProtKB", "id": "P38115", "url": "https://www.uniprot.org/uniprotkb/P38115" } ], "pmid": "" }, { "name": "D-arabinose 1-dehydrogenase (NADP+) activity", "id": "GO:0106271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106271", "evidence": [ { "database": "UniProtKB", "id": "P38115", "url": "https://www.uniprot.org/uniprotkb/P38115" } ], "pmid": "" }, { "name": "diacetyl reductase ((S)-acetoin forming) (NAD+) activity", "id": "GO:0052588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052588", "evidence": [ { "database": "UniProtKB", "id": "P38115", "url": "https://www.uniprot.org/uniprotkb/P38115" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38115-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000353", "url": "https://www.yeastgenome.org/locus/S000000353" }, { "database": "iPTMnet", "id": "P38115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38115-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Thr151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38115", "url": "https://www.uniprot.org/uniprotkb/P38115" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38115" }, { "database": "SGD", "id": "S000000353", "url": "https://www.yeastgenome.org/locus/S000000353" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38115-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Ser293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000353", "url": "https://www.yeastgenome.org/locus/S000000353" }, { "database": "iPTMnet", "id": "P38115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38115-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Ser294", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38115" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000353", "url": "https://www.yeastgenome.org/locus/S000000353" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38115-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Ser295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000353", "url": "https://www.yeastgenome.org/locus/S000000353" }, { "database": "iPTMnet", "id": "P38115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38115-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38115" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38115-1", "start_pos": "333", "end_pos": "333", "site_lbl": "Thr333", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000353", "url": "https://www.yeastgenome.org/locus/S000000353" }, { "database": "iPTMnet", "id": "P38115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38115-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Ser7", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000353", "url": "https://www.yeastgenome.org/locus/S000000353" }, { "database": "iPTMnet", "id": "P38115", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38115" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38115-1" }, { "uniprot_canonical_ac": "P38116-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 183, "chemical_mass": 20434.0, "gene_names": "ARL1;ARF3;ARL1;DLP2;YBR1216", "protein_name": "ADP-ribosylation factor-like protein 1", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "protein localization to Golgi apparatus", "id": "GO:0034067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034067", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "protein-containing complex localization", "id": "GO:0031503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031503", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P38116", "url": "https://www.uniprot.org/uniprotkb/P38116" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38116-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000368", "url": "https://www.yeastgenome.org/locus/S000000368" }, { "database": "iPTMnet", "id": "P38116", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38116" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38116-1" }, { "uniprot_canonical_ac": "P38128-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 452, "chemical_mass": 49414.0, "gene_names": "SMP1;SMP1;YBR1245", "protein_name": "Transcription factor SMP1", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0070050", "name": "neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language", "description": "An autosomal dominant intellectual developmental disorder that is characterized by global developmental delay with hypotonia, poor motor development with limited walking, impaired intellectual development with poor or absent speech, and behavioral abnormalities and that has_material_basis_in an autosomal dominant mutation of the MEF2C gene on chromosome 5q14.3.", "url": "https://disease-ontology.org/term/DOID:0070050", "evidence": [ { "id": "0070050", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070050" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding, bending", "id": "GO:0008301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008301", "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "pmid": "" }, { "name": "cellular response to osmotic stress", "id": "GO:0071470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071470", "evidence": [ { "database": "UniProtKB", "id": "P38128", "url": "https://www.uniprot.org/uniprotkb/P38128" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38128-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Ser348", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38128" }, { "database": "PubMed", "id": "12482976", "url": "https://glygen.org/publication/PubMed/12482976" }, { "database": "SGD", "id": "S000000386", "url": "https://www.yeastgenome.org/locus/S000000386" } ] } ] }, { "uniprot_canonical_ac": "P38128-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Ser353", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000386", "url": "https://www.yeastgenome.org/locus/S000000386" }, { "database": "iPTMnet", "id": "P38128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38128" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38128-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Thr355", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000386", "url": "https://www.yeastgenome.org/locus/S000000386" }, { "database": "iPTMnet", "id": "P38128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38128" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38128-1", "start_pos": "357", "end_pos": "357", "site_lbl": "Ser357", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38128" }, { "database": "PubMed", "id": "12482976", "url": "https://glygen.org/publication/PubMed/12482976" }, { "database": "SGD", "id": "S000000386", "url": "https://www.yeastgenome.org/locus/S000000386" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38128-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Thr365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38128" }, { "database": "PubMed", "id": "12482976", "url": "https://glygen.org/publication/PubMed/12482976" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000386", "url": "https://www.yeastgenome.org/locus/S000000386" } ] } ] }, { "uniprot_canonical_ac": "P38128-1", "start_pos": "375", "end_pos": "375", "site_lbl": "Ser375", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38128" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38128-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Ser376", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38128" }, { "database": "PubMed", "id": "12482976", "url": "https://glygen.org/publication/PubMed/12482976" }, { "database": "SGD", "id": "S000000386", "url": "https://www.yeastgenome.org/locus/S000000386" } ] } ] }, { "uniprot_canonical_ac": "P38128-1", "start_pos": "425", "end_pos": "425", "site_lbl": "Ser425", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000386", "url": "https://www.yeastgenome.org/locus/S000000386" }, { "database": "iPTMnet", "id": "P38128", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38128" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P38128-1" }, { "uniprot_canonical_ac": "P38130-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 404, "chemical_mass": 47482.0, "gene_names": "KTR3;KTR3;YBR1445", "protein_name": "Probable mannosyltransferase KTR3", "disease": [], "biological_process": [ { "name": "cell wall mannoprotein biosynthetic process", "id": "GO:0000032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000032", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" }, { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" } ], "molecular_function": [ { "name": "alpha-1,2-mannosyltransferase activity", "id": "GO:0000026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000026", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" }, { "name": "mannosyltransferase activity", "id": "GO:0000030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000030", "evidence": [ { "database": "UniProtKB", "id": "P38130", "url": "https://www.uniprot.org/uniprotkb/P38130" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38130-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000409", "url": "https://www.yeastgenome.org/locus/S000000409" }, { "database": "iPTMnet", "id": "P38130", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38130" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38130-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000409", "url": "https://www.yeastgenome.org/locus/S000000409" }, { "database": "iPTMnet", "id": "P38130", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38130" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P38130-1" }, { "uniprot_canonical_ac": "P38137-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38137", "url": "https://www.uniprot.org/uniprotkb/P38137" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 543, "chemical_mass": 60489.0, "gene_names": "PCS60;AAE3;FAT2;PCS60;YBR1512", "protein_name": "Oxalate--CoA ligase", "disease": [ { "disease_id": "DOID:0111263", "name": "combined malonic and methylmalonic acidemia", "description": "An organic acidemia characterized by elevated levels of methylmalonic acid and malonic acid in body fluids typically resulting in developmental delay and failure to thrive in children and neurological symptoms in adults that has_material_basis_in homozygous or compound heterozygous mutation in ACSF3 on 16q24.3.", "url": "https://disease-ontology.org/term/DOID:0111263", "evidence": [ { "id": "0111263", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111263" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P38137", "url": "https://www.uniprot.org/uniprotkb/P38137" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38137", "url": "https://www.uniprot.org/uniprotkb/P38137" } ], "pmid": "" }, { "name": "medium-chain fatty acid-CoA ligase activity", "id": "GO:0031956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031956", "evidence": [ { "database": "UniProtKB", "id": "P38137", "url": "https://www.uniprot.org/uniprotkb/P38137" } ], "pmid": "" }, { "name": "oxalate-CoA ligase activity", "id": "GO:0050203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050203", "evidence": [ { "database": "UniProtKB", "id": "P38137", "url": "https://www.uniprot.org/uniprotkb/P38137" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38137", "url": "https://www.uniprot.org/uniprotkb/P38137" } ], "pmid": "" }, { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "P38137", "url": "https://www.uniprot.org/uniprotkb/P38137" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "P38137", "url": "https://www.uniprot.org/uniprotkb/P38137" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "P38137", "url": "https://www.uniprot.org/uniprotkb/P38137" } ], "pmid": "" }, { "name": "oxalate catabolic process", "id": "GO:0033611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033611", "evidence": [ { "database": "UniProtKB", "id": "P38137", "url": "https://www.uniprot.org/uniprotkb/P38137" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P38137-1" }, { "uniprot_canonical_ac": "P38138-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 954, "chemical_mass": 110266.0, "gene_names": "ROT2;GLS2;ROT2;YBR1526", "protein_name": "Glucosidase 2 subunit alpha", "disease": [ { "disease_id": "DOID:0050770", "name": "polycystic liver disease", "description": "A liver disease that is characterized by the presence of multiple cysts located_in the liver.", "url": "https://disease-ontology.org/term/DOID:0050770", "evidence": [ { "id": "0050770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050770" } ], "weight": 0.0 }, { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:0110860", "name": "polycystic kidney disease 3", "description": "A autosomal dominant polycystic kidney disease that has_material_basis_in autosomal dominant inheritance of mutation in the GANAB gene on chromosome 11q12.3.", "url": "https://disease-ontology.org/term/DOID:0110860", "evidence": [ { "id": "0110860", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110860" } ], "weight": 0.0 } ], "biological_process": [ { "name": "polysaccharide biosynthetic process", "id": "GO:0000271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000271", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" }, { "name": "fungal-type cell wall beta-glucan biosynthetic process", "id": "GO:0070880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070880", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" }, { "name": "glucosidase II complex", "id": "GO:0017177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017177", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" }, { "name": "glucan 1,3-alpha-glucosidase activity", "id": "GO:0033919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033919", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" }, { "name": "alpha-glucosidase activity", "id": "GO:0090599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090599", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" }, { "name": "Glc2Man9GlcNAc2 oligosaccharide glucosidase activity", "id": "GO:0106407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106407", "evidence": [ { "database": "UniProtKB", "id": "P38138", "url": "https://www.uniprot.org/uniprotkb/P38138" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38138-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Asn114", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 114, "start_aa": "Asn", "end_pos": 114, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn114", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Asn126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 126, "start_aa": "Asn", "end_pos": 126, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn126", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Asn142", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 142, "start_aa": "Asn", "end_pos": 142, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn142", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Asn173", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 173, "start_aa": "Asn", "end_pos": 173, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn173", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "345", "end_pos": "345", "site_lbl": "Asn345", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 345, "start_aa": "Asn", "end_pos": 345, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn345", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "652", "end_pos": "652", "site_lbl": "Thr652", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 652, "start_aa": "Thr", "end_pos": 652, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr652", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "783", "end_pos": "783", "site_lbl": "Asn783", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 783, "start_aa": "Asn", "end_pos": 783, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn783", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "791", "end_pos": "791", "site_lbl": "Asn791", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 791, "start_aa": "Asn", "end_pos": 791, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn791", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "867", "end_pos": "867", "site_lbl": "Asn867", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 867, "start_aa": "Asn", "end_pos": 867, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn867", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "880", "end_pos": "880", "site_lbl": "Asn880", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 880, "start_aa": "Asn", "end_pos": 880, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn880", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "907", "end_pos": "907", "site_lbl": "Asn907", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 907, "start_aa": "Asn", "end_pos": 907, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn907", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "941", "end_pos": "941", "site_lbl": "Asn941", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 941, "start_aa": "Asn", "end_pos": 941, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn941", "evidence": [ { "id": "P38138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38138#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38138-1", "start_pos": "793", "end_pos": "793", "site_lbl": "Ser793", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000433", "url": "https://www.yeastgenome.org/locus/S000000433" }, { "database": "iPTMnet", "id": "P38138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38138" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P38138-1" }, { "uniprot_canonical_ac": "P38139-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 375, "chemical_mass": 43287.0, "gene_names": "LDH1;LDH1;YBR1444", "protein_name": "Lipid droplet hydrolase 1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity, acting on ester bonds", "id": "GO:0016788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" } ], "pmid": "" }, { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" } ], "pmid": "" }, { "name": "acylglycerol catabolic process", "id": "GO:0046464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046464", "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38139-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Ser14", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000408", "url": "https://www.yeastgenome.org/locus/S000000408" }, { "database": "iPTMnet", "id": "P38139", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38139" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38139-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes serine hydrolase activity.", "evidence": [ { "database": "UniProtKB", "id": "P38139", "url": "https://www.uniprot.org/uniprotkb/P38139" }, { "database": "PubMed", "id": "21478434", "url": "https://glygen.org/publication/PubMed/21478434" } ] } ] } ], "record_id": "P38139-1" }, { "uniprot_canonical_ac": "P38140-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 529, "chemical_mass": 60311.0, "gene_names": "ERT1;ERT1;YBR1622", "protein_name": "Transcription activator of gluconeogenesis ERT1", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "positive regulation of gluconeogenesis", "id": "GO:0045722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045722", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "carbon catabolite repression of transcription", "id": "GO:0045013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045013", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "carbon catabolite activation of transcription", "id": "GO:0045991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045991", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38140", "url": "https://www.uniprot.org/uniprotkb/P38140" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38140-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Tyr105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000443", "url": "https://www.yeastgenome.org/locus/S000000443" }, { "database": "iPTMnet", "id": "P38140", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38140" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38140-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000443", "url": "https://www.yeastgenome.org/locus/S000000443" }, { "database": "iPTMnet", "id": "P38140", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38140" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38140-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Ser112", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000443", "url": "https://www.yeastgenome.org/locus/S000000443" }, { "database": "iPTMnet", "id": "P38140", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38140" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38140-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000443", "url": "https://www.yeastgenome.org/locus/S000000443" }, { "database": "iPTMnet", "id": "P38140", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38140" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38140-1" }, { "uniprot_canonical_ac": "P38143-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 162, "chemical_mass": 18406.0, "gene_names": "GPX2;AMI1;GPX2;YBR1632", "protein_name": "Glutathione peroxidase-like peroxiredoxin 2", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0112298", "name": "spondylometaphyseal dysplasia Sedaghatian type", "description": "A spondylometaphyseal dysplasia characterized by neonatal lethality, severe metaphyseal chondrodysplasia with mild limb shortening, platyspondyly, delayed epiphyseal ossification, irregular iliac crests, pulmonary hemorrhage, severe hypotonia and cardiorespiratory problems that has_material_basis_in homozygous or compound heterozygous mutation in the GPX4 gene on chromosome 19p13.3.", "url": "https://disease-ontology.org/term/DOID:0112298", "evidence": [ { "id": "0112298", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112298" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" } ], "pmid": "" } ], "molecular_function": [ { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" } ], "pmid": "" }, { "name": "phospholipid-hydroperoxide glutathione peroxidase activity", "id": "GO:0047066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047066", "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" } ], "pmid": "" }, { "name": "thioredoxin-dependent peroxiredoxin activity", "id": "GO:0140824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140824", "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38143-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38143" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P38143-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000448", "url": "https://www.yeastgenome.org/locus/S000000448" }, { "database": "iPTMnet", "id": "P38143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38143" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38143-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Thr2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38143" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000448", "url": "https://www.yeastgenome.org/locus/S000000448" } ] } ] }, { "uniprot_canonical_ac": "P38143-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38143" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000448", "url": "https://www.yeastgenome.org/locus/S000000448" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38143-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Ser75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000448", "url": "https://www.yeastgenome.org/locus/S000000448" }, { "database": "iPTMnet", "id": "P38143", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38143" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38143-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Cys37", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Prevents oxidation of the protein.", "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" }, { "database": "PubMed", "id": "16251189", "url": "https://glygen.org/publication/PubMed/16251189" } ] } ] }, { "uniprot_canonical_ac": "P38143-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Cys83", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Prevents oxidation of the protein.", "evidence": [ { "database": "UniProtKB", "id": "P38143", "url": "https://www.uniprot.org/uniprotkb/P38143" }, { "database": "PubMed", "id": "16251189", "url": "https://glygen.org/publication/PubMed/16251189" } ] } ] } ], "record_id": "P38143-1" }, { "uniprot_canonical_ac": "P38144-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1129, "chemical_mass": 131102.0, "gene_names": "ISW1;ISW1;SGN2;YBR1633", "protein_name": "ISWI chromatin-remodeling complex ATPase ISW1", "disease": [ { "disease_id": "DOID:331", "name": "central nervous system disease", "description": "A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system.", "url": "https://disease-ontology.org/term/DOID:331", "evidence": [ { "id": "331", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:331" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of RNA export from nucleus", "id": "GO:0046832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046832", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "response to heat", "id": "GO:0009408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009408", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "negative regulation of IRE1-mediated unfolded protein response", "id": "GO:1903895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903895", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "sister chromatid cohesion", "id": "GO:0007062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007062", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "termination of RNA polymerase I transcription", "id": "GO:0006363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006363", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "termination of RNA polymerase II transcription", "id": "GO:0006369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006369", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "DNA-templated transcription elongation", "id": "GO:0006354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006354", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": "GO:1902275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902275", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "regulation of transcriptional start site selection at RNA polymerase II promoter", "id": "GO:0001178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001178", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "rDNA binding", "id": "GO:0000182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000182", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "nucleosome array spacer activity", "id": "GO:0140750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140750", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "Isw1a complex", "id": "GO:0036436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036436", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "Isw1b complex", "id": "GO:0036437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036437", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" }, { "name": "nucleolar chromatin", "id": "GO:0030874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030874", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38144-1", "start_pos": "792", "end_pos": "792", "site_lbl": "Thr792", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 792, "start_aa": "Thr", "end_pos": 792, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr792", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "825", "end_pos": "825", "site_lbl": "Thr825", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 825, "start_aa": "Thr", "end_pos": 825, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr825", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38144", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38144" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "1038", "end_pos": "1038", "site_lbl": "Thr1038", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "1089", "end_pos": "1089", "site_lbl": "Thr1089", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "1101", "end_pos": "1101", "site_lbl": "Ser1101", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "1109", "end_pos": "1109", "site_lbl": "Thr1109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "1110", "end_pos": "1110", "site_lbl": "Ser1110", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "1114", "end_pos": "1114", "site_lbl": "Thr1114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "1127", "end_pos": "1127", "site_lbl": "Thr1127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "1128", "end_pos": "1128", "site_lbl": "Thr1128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "415", "end_pos": "415", "site_lbl": "Ser415", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Tyr430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Ser455", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "673", "end_pos": "673", "site_lbl": "Ser673", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "685", "end_pos": "685", "site_lbl": "Ser685", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "687", "end_pos": "687", "site_lbl": "Thr687", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "688", "end_pos": "688", "site_lbl": "Ser688", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "689", "end_pos": "689", "site_lbl": "Thr689", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "691", "end_pos": "691", "site_lbl": "Ser691", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "694", "end_pos": "694", "site_lbl": "Thr694", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "699", "end_pos": "699", "site_lbl": "Ser699", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "721", "end_pos": "721", "site_lbl": "Ser721", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "760", "end_pos": "760", "site_lbl": "Ser760", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "780", "end_pos": "780", "site_lbl": "Tyr780", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "781", "end_pos": "781", "site_lbl": "Tyr781", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "791", "end_pos": "791", "site_lbl": "Ser791", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "831", "end_pos": "831", "site_lbl": "Tyr831", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "846", "end_pos": "846", "site_lbl": "Ser846", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "865", "end_pos": "865", "site_lbl": "Ser865", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000449", "url": "https://www.yeastgenome.org/locus/S000000449" }, { "database": "iPTMnet", "id": "P38144", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38144" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38144-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Lys227", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Abolishes ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "P38144", "url": "https://www.uniprot.org/uniprotkb/P38144" }, { "database": "PubMed", "id": "10090725", "url": "https://glygen.org/publication/PubMed/10090725" } ] } ] } ], "record_id": "P38144-1" }, { "uniprot_canonical_ac": "P38146-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 199, "chemical_mass": 21834.0, "gene_names": "YPT10;YBR1733;YPT10", "protein_name": "GTP-binding protein YPT10", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" }, { "name": "guanyl nucleotide binding", "id": "GO:0019001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019001", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "P38146", "url": "https://www.uniprot.org/uniprotkb/P38146" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38146-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000468", "url": "https://www.yeastgenome.org/locus/S000000468" }, { "database": "iPTMnet", "id": "P38146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38146" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38146-1" }, { "uniprot_canonical_ac": "P38149-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 878, "chemical_mass": 98071.0, "gene_names": "DUG2;DUG2;YBR2018", "protein_name": "Probable di- and tripeptidase DUG2", "disease": [], "biological_process": [ { "name": "glutathione catabolic process", "id": "GO:0006751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006751", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" }, { "name": "glutathione hydrolase complex", "id": "GO:0061672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061672", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" } ], "molecular_function": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" }, { "name": "omega peptidase activity", "id": "GO:0008242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008242", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" }, { "name": "dipeptidase activity", "id": "GO:0016805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016805", "evidence": [ { "database": "UniProtKB", "id": "P38149", "url": "https://www.uniprot.org/uniprotkb/P38149" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38149-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000485", "url": "https://www.yeastgenome.org/locus/S000000485" }, { "database": "iPTMnet", "id": "P38149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38149-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000485", "url": "https://www.yeastgenome.org/locus/S000000485" }, { "database": "iPTMnet", "id": "P38149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38149" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38149-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38149", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38149" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000485", "url": "https://www.yeastgenome.org/locus/S000000485" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38149-1" }, { "uniprot_canonical_ac": "P38153-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38153", "url": "https://www.uniprot.org/uniprotkb/P38153" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 483, "chemical_mass": 54837.0, "gene_names": "APM3;APM3;YBR2035;YKS6", "protein_name": "AP-3 complex subunit mu", "disease": [], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P38153", "url": "https://www.uniprot.org/uniprotkb/P38153" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P38153", "url": "https://www.uniprot.org/uniprotkb/P38153" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P38153", "url": "https://www.uniprot.org/uniprotkb/P38153" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "P38153", "url": "https://www.uniprot.org/uniprotkb/P38153" } ], "pmid": "" } ], "cellular_component": [ { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P38153", "url": "https://www.uniprot.org/uniprotkb/P38153" } ], "pmid": "" }, { "name": "AP-3 adaptor complex", "id": "GO:0030123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030123", "evidence": [ { "database": "UniProtKB", "id": "P38153", "url": "https://www.uniprot.org/uniprotkb/P38153" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "P38153", "url": "https://www.uniprot.org/uniprotkb/P38153" } ], "pmid": "" } ], "molecular_function": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "P38153", "url": "https://www.uniprot.org/uniprotkb/P38153" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38153-1", "start_pos": "153", "end_pos": "153", "site_lbl": "Ser153", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000492", "url": "https://www.yeastgenome.org/locus/S000000492" }, { "database": "iPTMnet", "id": "P38153", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38153" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38153-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38153", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38153" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000492", "url": "https://www.yeastgenome.org/locus/S000000492" } ] } ] }, { "uniprot_canonical_ac": "P38153-1", "start_pos": "459", "end_pos": "459", "site_lbl": "Thr459", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38153", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38153" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000492", "url": "https://www.yeastgenome.org/locus/S000000492" } ] } ] } ], "record_id": "P38153-1" }, { "uniprot_canonical_ac": "P38165-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 486, "chemical_mass": 54140.0, "gene_names": "RTG3;RTG3;YBL0810", "protein_name": "Retrograde regulation protein 3", "disease": [ { "disease_id": "DOID:0090002", "name": "Tietz syndrome", "description": "A syndrome that is characterized by congenital profound bilateral sensorineural hearing loss and generalized albino-like hypopigmentation of skin, eyes and hair that has_material_basis_in mutation in the MITF gene on chromosome 3p13.", "url": "https://disease-ontology.org/term/DOID:0090002", "evidence": [ { "id": "0090002", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090002" } ], "weight": 0.0 }, { "disease_id": "DOID:0090100", "name": "ocular albinism with sensorineural deafness", "description": "An ocular albinism that is characterized by deafness and vestibular dysfunction and has_material_basis_in digenic inheritance of a mutation in the transcription factor gene MITF on chromosome 3p13 and in the tyrosinase TYR gene on chromosome 11q14.3 that MITF regulates.", "url": "https://disease-ontology.org/term/DOID:0090100", "evidence": [ { "id": "0090100", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090100" } ], "weight": 0.0 }, { "disease_id": "DOID:0110948", "name": "Waardenburg syndrome type 1", "description": "A Waardenburg syndrome characterized by autosomal dominant inheritance of congenital deafness, pigmentation anomalies of eyes, hair, and skin,and dystopia canthorum that has_material_basis_in heterozygous mutation in the PAX3 gene on chromosome 2q36.", "url": "https://disease-ontology.org/term/DOID:0110948", "evidence": [ { "id": "0110948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110948" } ], "weight": 0.0 }, { "disease_id": "DOID:0110950", "name": "Waardenburg syndrome type 2A", "description": "A Waardenburg syndrome characterized by pigmentary abnormalities of the hair, skin, and eyes, congenital sensorineural hearing loss, and absence of lateral displacement of the inner canthus of each eye that has_material_basis_in heterozygous mutation in the MITF gene on chromosome 3p13.", "url": "https://disease-ontology.org/term/DOID:0110950", "evidence": [ { "id": "0110950", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110950" } ], "weight": 0.0 }, { "disease_id": "DOID:13533", "name": "osteopetrosis", "description": "An osteosclerosis that has_material_basis_in lack of bone resorption which results_in abnormally hard and brittle bones.", "url": "https://disease-ontology.org/term/DOID:13533", "evidence": [ { "id": "13533", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13533" } ], "weight": 0.0 }, { "disease_id": "DOID:14021", "name": "Tietze's syndrome", "description": "A cartilage disease that is characterized by localized tenderness and non-suppurative swelling, typically associated with the 2nd or 3rd costal cartilages unilaterally caused by inflammation of one or more of the costal cartilages and that has symptom anterior chest pain.", "url": "https://disease-ontology.org/term/DOID:14021", "evidence": [ { "id": "14021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14021" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:3211", "name": "lysosomal storage disease", "description": "An inherited metabolic disorder that involve an abnormal accumulation of substances inside the lysosome resulting from defects in lysosomal function.", "url": "https://disease-ontology.org/term/DOID:3211", "evidence": [ { "id": "3211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3211" } ], "weight": 0.0 }, { "disease_id": "DOID:4997", "name": "Camurati-Engelmann disease", "description": "An osteosclerosis characterized by the cortical thickening of the diaphyses of the long bones.", "url": "https://disease-ontology.org/term/DOID:4997", "evidence": [ { "id": "4997", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4997" } ], "weight": 0.0 }, { "disease_id": "DOID:6846", "name": "familial melanoma", "description": "", "url": "https://disease-ontology.org/term/DOID:6846", "evidence": [ { "id": "6846", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6846" } ], "weight": 0.0 }, { "disease_id": "DOID:9258", "name": "Waardenburg syndrome", "description": "A syndrome characterized by varying degrees of deafness, minor defects in structures arising from the neural crest and pigmentation anomalies of the hair, the skin and/or the iris of both eyes.", "url": "https://disease-ontology.org/term/DOID:9258", "evidence": [ { "id": "9258", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9258" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cellular response to oleic acid", "id": "GO:0071400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071400", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "peroxisome fission", "id": "GO:0016559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016559", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "mitochondria-nucleus signaling pathway", "id": "GO:0031930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031930", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38165-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38165", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38165" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 113, "start_aa": "Ser", "end_pos": 113, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser113", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38165", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38165" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Thr120", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 120, "start_aa": "Thr", "end_pos": 120, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr120", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38165", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38165" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Ser123", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 123, "start_aa": "Ser", "end_pos": 123, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser123", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38165", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38165" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 125, "start_aa": "Ser", "end_pos": 125, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser125", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38165", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38165" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Ser126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 126, "start_aa": "Ser", "end_pos": 126, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser126", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38165", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38165" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "134", "end_pos": "134", "site_lbl": "Ser134", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 134, "start_aa": "Ser", "end_pos": 134, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser134", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38165", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38165" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 135, "start_aa": "Ser", "end_pos": 135, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser135", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38165", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38165" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 137, "start_aa": "Ser", "end_pos": 137, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser137", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38165", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38165" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 142, "start_aa": "Ser", "end_pos": 142, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser142", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38165", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38165" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Tyr136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Tyr140", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Thr150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Thr197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "22956768", "url": "https://glygen.org/publication/PubMed/22956768" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Tyr221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Ser222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22956768", "url": "https://glygen.org/publication/PubMed/22956768" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Ser227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "22956768", "url": "https://glygen.org/publication/PubMed/22956768" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Ser230", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Ser231", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Ser236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "240", "end_pos": "240", "site_lbl": "Ser240", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Ser241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Thr249", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "22956768", "url": "https://glygen.org/publication/PubMed/22956768" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Thr255", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Ser258", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Thr262", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Thr278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Ser279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Ser371", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Ser376", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "22956768", "url": "https://glygen.org/publication/PubMed/22956768" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Ser394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "455", "end_pos": "455", "site_lbl": "Ser455", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "479", "end_pos": "479", "site_lbl": "Tyr479", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "485", "end_pos": "485", "site_lbl": "Ser485", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Thr69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Ser72", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Ser81", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38165", "url": "https://www.uniprot.org/uniprotkb/P38165" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Ser87", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P38165-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Tyr96", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000199", "url": "https://www.yeastgenome.org/locus/S000000199" }, { "database": "iPTMnet", "id": "P38165", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38165" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P38165-1" }, { "uniprot_canonical_ac": "P38193-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38193", "url": "https://www.uniprot.org/uniprotkb/P38193" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 441, "chemical_mass": 50655.0, "gene_names": "PSY4;HSM6;HTP3;PSY4;YBL0402", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "disease": [], "biological_process": [ { "name": "meiotic recombination checkpoint signaling", "id": "GO:0051598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051598", "evidence": [ { "database": "UniProtKB", "id": "P38193", "url": "https://www.uniprot.org/uniprotkb/P38193" } ], "pmid": "" }, { "name": "negative regulation of DNA damage checkpoint", "id": "GO:2000002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000002", "evidence": [ { "database": "UniProtKB", "id": "P38193", "url": "https://www.uniprot.org/uniprotkb/P38193" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38193", "url": "https://www.uniprot.org/uniprotkb/P38193" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38193", "url": "https://www.uniprot.org/uniprotkb/P38193" } ], "pmid": "" }, { "name": "protein phosphatase 4 complex", "id": "GO:0030289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030289", "evidence": [ { "database": "UniProtKB", "id": "P38193", "url": "https://www.uniprot.org/uniprotkb/P38193" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "P38193", "url": "https://www.uniprot.org/uniprotkb/P38193" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38193-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Ser165", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Ser189", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Ser263", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Thr293", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Thr320", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826" }, { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "PubMed", "id": "35977012", "url": "https://glygen.org/publication/PubMed/35977012" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Tyr334", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Ser337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "35977012", "url": "https://glygen.org/publication/PubMed/35977012" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Ser339", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Thr347", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38193", "url": "https://www.uniprot.org/uniprotkb/P38193" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "35977012", "url": "https://glygen.org/publication/PubMed/35977012" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Ser360", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Ser364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "35977012", "url": "https://glygen.org/publication/PubMed/35977012" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "381", "end_pos": "381", "site_lbl": "Ser381", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Ser382", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "409", "end_pos": "409", "site_lbl": "Ser409", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "35977012", "url": "https://glygen.org/publication/PubMed/35977012" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "411", "end_pos": "411", "site_lbl": "Ser411", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "413", "end_pos": "413", "site_lbl": "Ser413", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "414", "end_pos": "414", "site_lbl": "Ser414", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "415", "end_pos": "415", "site_lbl": "Ser415", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P38110-1", "kinase_gene_name": "TEL1", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "P38111-1", "kinase_gene_name": "MEC1", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20190278", "url": "https://glygen.org/publication/PubMed/20190278" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "433", "end_pos": "433", "site_lbl": "Ser433", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38193-1", "start_pos": "434", "end_pos": "434", "site_lbl": "Ser434", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "evidence": [ { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000142", "url": "https://www.yeastgenome.org/locus/S000000142" }, { "database": "iPTMnet", "id": "P38193", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38193" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "35977012", "url": "https://glygen.org/publication/PubMed/35977012" } ] } ] } ], "record_id": "P38193-1" }, { "uniprot_canonical_ac": "P38210-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38210", "url": "https://www.uniprot.org/uniprotkb/P38210" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 180, "chemical_mass": 19792.0, "gene_names": "LDB7;LDB7;RSC14;YBL0322", "protein_name": "Chromatin structure-remodeling complex protein RSC14", "disease": [], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "P38210", "url": "https://www.uniprot.org/uniprotkb/P38210" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "P38210", "url": "https://www.uniprot.org/uniprotkb/P38210" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "P38210", "url": "https://www.uniprot.org/uniprotkb/P38210" } ], "pmid": "" } ], "cellular_component": [ { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P38210", "url": "https://www.uniprot.org/uniprotkb/P38210" } ], "pmid": "" }, { "name": "RSC-type complex", "id": "GO:0016586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016586", "evidence": [ { "database": "UniProtKB", "id": "P38210", "url": "https://www.uniprot.org/uniprotkb/P38210" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38210-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Ser142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000102", "url": "https://www.yeastgenome.org/locus/S000000102" }, { "database": "iPTMnet", "id": "P38210", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38210" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38210-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000102", "url": "https://www.yeastgenome.org/locus/S000000102" }, { "database": "iPTMnet", "id": "P38210", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38210" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38210-1" }, { "uniprot_canonical_ac": "P38217-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 918, "chemical_mass": 103681.0, "gene_names": "KAP104;KAP104;YBR0224", "protein_name": "Importin subunit beta-2", "disease": [ { "disease_id": "DOID:0081262", "name": "intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies", "description": "An autosomal dominant intellectual developmental disorder that is characterized by global developmental delay with impaired intellectual development and poor or absent speech, hypotonia, ophthalmologic abnormalities, and nonspecific dysmorphic features, and that has_material_basis_in heterozygous mutation in the TNPO2 gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0081262", "evidence": [ { "id": "0081262", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081262" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" } ], "biological_process": [ { "name": "exit from mitosis", "id": "GO:0010458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010458", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" } ], "molecular_function": [ { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "P38217", "url": "https://www.uniprot.org/uniprotkb/P38217" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P38217-1" }, { "uniprot_canonical_ac": "P38251-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 354, "chemical_mass": 39942.0, "gene_names": "RFC5;RFC5;YBR0810", "protein_name": "Replication factor C subunit 5", "disease": [], "biological_process": [ { "name": "leading strand elongation", "id": "GO:0006272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006272", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" }, { "name": "sister chromatid cohesion", "id": "GO:0007062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007062", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" }, { "name": "Ctf18 RFC-like complex", "id": "GO:0031390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031390", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" }, { "name": "Elg1 RFC-like complex", "id": "GO:0031391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031391", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" }, { "name": "DNA replication factor C complex", "id": "GO:0005663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005663", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" }, { "name": "Rad17 RFC-like complex", "id": "GO:0031389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031389", "evidence": [ { "database": "UniProtKB", "id": "P38251", "url": "https://www.uniprot.org/uniprotkb/P38251" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38251-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38251" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38251-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Tyr8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38251" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] } ], "record_id": "P38251-1" }, { "uniprot_canonical_ac": "P38255-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 430, "chemical_mass": 48629.0, "gene_names": "RXT2;RAF60;RXT2;YBR0822", "protein_name": "Transcriptional regulatory protein RXT2", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "negative regulation of rDNA heterochromatin formation", "id": "GO:0061188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061188", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "conjugation with cellular fusion", "id": "GO:0000747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000747", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "invasive growth in response to glucose limitation", "id": "GO:0001403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001403", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "negative regulation of silent mating-type cassette heterochromatin formation", "id": "GO:0061186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061186", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "positive regulation of invasive growth in response to glucose limitation", "id": "GO:2000219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000219", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "Rpd3L-Expanded complex", "id": "GO:0070210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070210", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" }, { "name": "Rpd3L complex", "id": "GO:0033698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033698", "evidence": [ { "database": "UniProtKB", "id": "P38255", "url": "https://www.uniprot.org/uniprotkb/P38255" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38255-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38255" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000299", "url": "https://www.yeastgenome.org/locus/S000000299" } ] } ] }, { "uniprot_canonical_ac": "P38255-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Thr144", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38255" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38255-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Thr167", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000299", "url": "https://www.yeastgenome.org/locus/S000000299" }, { "database": "iPTMnet", "id": "P38255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38255" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38255-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000299", "url": "https://www.yeastgenome.org/locus/S000000299" }, { "database": "iPTMnet", "id": "P38255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38255" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38255-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000299", "url": "https://www.yeastgenome.org/locus/S000000299" }, { "database": "iPTMnet", "id": "P38255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38255" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38255-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000299", "url": "https://www.yeastgenome.org/locus/S000000299" }, { "database": "iPTMnet", "id": "P38255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38255" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38255-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Ser249", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38255" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000299", "url": "https://www.yeastgenome.org/locus/S000000299" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38255-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38255" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000299", "url": "https://www.yeastgenome.org/locus/S000000299" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38255-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Ser396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000299", "url": "https://www.yeastgenome.org/locus/S000000299" }, { "database": "iPTMnet", "id": "P38255", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38255" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38255-1" }, { "uniprot_canonical_ac": "P38266-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 947, "chemical_mass": 103863.0, "gene_names": "AIM3;AIM3;YBR0901", "protein_name": "Altered inheritance of mitochondria protein 3", "disease": [], "cellular_component": [ { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" } ], "pmid": "" } ], "biological_process": [ { "name": "barbed-end actin filament capping", "id": "GO:0051016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051016", "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" } ], "pmid": "" }, { "name": "actin cortical patch assembly", "id": "GO:0000147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000147", "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38266-1", "start_pos": "470", "end_pos": "470", "site_lbl": "Thr470", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 470, "start_aa": "Thr", "end_pos": 470, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr470", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Thr471", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 471, "start_aa": "Thr", "end_pos": 471, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr471", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "472", "end_pos": "472", "site_lbl": "Ser472", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 472, "start_aa": "Ser", "end_pos": 472, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser472", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "473", "end_pos": "473", "site_lbl": "Ser473", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 473, "start_aa": "Ser", "end_pos": 473, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser473", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "476", "end_pos": "476", "site_lbl": "Ser476", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 476, "start_aa": "Ser", "end_pos": 476, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser476", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "631", "end_pos": "631", "site_lbl": "Ser631", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 631, "start_aa": "Ser", "end_pos": 631, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser631", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "636", "end_pos": "636", "site_lbl": "Ser636", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 636, "start_aa": "Ser", "end_pos": 636, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser636", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Ser640", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 640, "start_aa": "Ser", "end_pos": 640, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser640", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "642", "end_pos": "642", "site_lbl": "Ser642", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 642, "start_aa": "Ser", "end_pos": 642, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser642", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "667", "end_pos": "667", "site_lbl": "Ser667", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 667, "start_aa": "Ser", "end_pos": 667, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser667", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "669", "end_pos": "669", "site_lbl": "Ser669", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 669, "start_aa": "Ser", "end_pos": 669, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser669", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "670", "end_pos": "670", "site_lbl": "Ser670", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 670, "start_aa": "Ser", "end_pos": 670, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser670", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "672", "end_pos": "672", "site_lbl": "Ser672", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 672, "start_aa": "Ser", "end_pos": 672, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser672", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "673", "end_pos": "673", "site_lbl": "Ser673", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 673, "start_aa": "Ser", "end_pos": 673, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser673", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "675", "end_pos": "675", "site_lbl": "Ser675", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 675, "start_aa": "Ser", "end_pos": 675, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser675", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "676", "end_pos": "676", "site_lbl": "Ser676", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 676, "start_aa": "Ser", "end_pos": 676, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser676", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "729", "end_pos": "729", "site_lbl": "Thr729", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 729, "start_aa": "Thr", "end_pos": 729, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr729", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "746", "end_pos": "746", "site_lbl": "Ser746", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 746, "start_aa": "Ser", "end_pos": 746, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser746", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "750", "end_pos": "750", "site_lbl": "Ser750", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 750, "start_aa": "Ser", "end_pos": 750, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser750", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "751", "end_pos": "751", "site_lbl": "Ser751", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 751, "start_aa": "Ser", "end_pos": 751, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser751", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "760", "end_pos": "760", "site_lbl": "Ser760", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 760, "start_aa": "Ser", "end_pos": 760, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser760", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "766", "end_pos": "766", "site_lbl": "Ser766", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 766, "start_aa": "Ser", "end_pos": 766, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser766", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "767", "end_pos": "767", "site_lbl": "Ser767", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 767, "start_aa": "Ser", "end_pos": 767, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser767", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "773", "end_pos": "773", "site_lbl": "Ser773", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 773, "start_aa": "Ser", "end_pos": 773, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser773", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "915", "end_pos": "915", "site_lbl": "Ser915", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 915, "start_aa": "Ser", "end_pos": 915, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser915", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "919", "end_pos": "919", "site_lbl": "Ser919", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 919, "start_aa": "Ser", "end_pos": 919, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser919", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38266", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38266" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Ser463", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "482", "end_pos": "482", "site_lbl": "Ser482", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "486", "end_pos": "486", "site_lbl": "Thr486", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Ser57", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "608", "end_pos": "608", "site_lbl": "Ser608", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "678", "end_pos": "678", "site_lbl": "Thr678", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "709", "end_pos": "709", "site_lbl": "Ser709", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "721", "end_pos": "721", "site_lbl": "Ser721", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "790", "end_pos": "790", "site_lbl": "Ser790", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "801", "end_pos": "801", "site_lbl": "Thr801", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "805", "end_pos": "805", "site_lbl": "Thr805", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "826", "end_pos": "826", "site_lbl": "Thr826", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "842", "end_pos": "842", "site_lbl": "Ser842", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "843", "end_pos": "843", "site_lbl": "Ser843", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "847", "end_pos": "847", "site_lbl": "Ser847", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "855", "end_pos": "855", "site_lbl": "Ser855", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "857", "end_pos": "857", "site_lbl": "Ser857", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "859", "end_pos": "859", "site_lbl": "Ser859", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "861", "end_pos": "861", "site_lbl": "Thr861", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38266", "url": "https://www.uniprot.org/uniprotkb/P38266" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "868", "end_pos": "868", "site_lbl": "Ser868", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38266-1", "start_pos": "914", "end_pos": "914", "site_lbl": "Tyr914", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38266", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38266" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000312", "url": "https://www.yeastgenome.org/locus/S000000312" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38266-1" }, { "uniprot_canonical_ac": "P38272-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 425, "chemical_mass": 47417.0, "gene_names": "SHE3;SHE3;YBR1005", "protein_name": "SWI5-dependent HO expression protein 3", "disease": [], "molecular_function": [ { "name": "sequence-specific mRNA binding", "id": "GO:1990825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990825", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" } ], "pmid": "" }, { "name": "cellular bud tip", "id": "GO:0005934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005934", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" } ], "pmid": "" }, { "name": "mating type switching", "id": "GO:0007533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007533", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" } ], "pmid": "" }, { "name": "endoplasmic reticulum inheritance", "id": "GO:0048309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048309", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38272-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "217", "end_pos": "217", "site_lbl": "Ser217", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Ser223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "233", "end_pos": "233", "site_lbl": "Ser233", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Thr237", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Ser239", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Ser27", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Thr295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Ser299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Ser306", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Ser307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Thr30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Ser343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "19429778", "url": "https://glygen.org/publication/PubMed/19429778" }, { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "E", "comment": "Prevents correct localization of ASH1 mRNA; when associated with E-361.", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" }, { "database": "PubMed", "id": "19429778", "url": "https://glygen.org/publication/PubMed/19429778" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Thr346", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Ser348", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "19429778", "url": "https://glygen.org/publication/PubMed/19429778" }, { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "E", "comment": "Prevents correct localization of ASH1 mRNA.", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" }, { "database": "PubMed", "id": "19429778", "url": "https://glygen.org/publication/PubMed/19429778" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Ser361", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "19429778", "url": "https://glygen.org/publication/PubMed/19429778" }, { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "E", "comment": "Prevents correct localization of ASH1 mRNA; when associated with E-343.", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" }, { "database": "PubMed", "id": "19429778", "url": "https://glygen.org/publication/PubMed/19429778" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Thr370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Ser372", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Thr383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "386", "end_pos": "386", "site_lbl": "Thr386", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Ser392", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Thr393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Ser394", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38272", "url": "https://www.uniprot.org/uniprotkb/P38272" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Thr396", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Ser398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Ser417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Thr59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Thr64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Thr65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38272-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000334", "url": "https://www.yeastgenome.org/locus/S000000334" }, { "database": "iPTMnet", "id": "P38272", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38272" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38272-1" }, { "uniprot_canonical_ac": "P38274-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 827, "chemical_mass": 95153.0, "gene_names": "HSL7;HSL7;YBR1008", "protein_name": "Protein arginine N-methyltransferase HSL7", "disease": [ { "disease_id": "DOID:0060250", "name": "idiopathic scoliosis", "description": "A scoliosis with no known cause.", "url": "https://disease-ontology.org/term/DOID:0060250", "evidence": [ { "id": "0060250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060250" } ], "weight": 0.0 }, { "disease_id": "DOID:2696", "name": "Leydig cell tumor", "description": "A sex cord-gonadal stromal tumor that secretes testosterone characterized by excessive proliferation of Leydig cells located_in ovary or testicle.", "url": "https://disease-ontology.org/term/DOID:2696", "evidence": [ { "id": "2696", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2696" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:4440", "name": "seminoma", "description": "A germinoma that has_material_basis_in cells that make sperm and eggs.", "url": "https://disease-ontology.org/term/DOID:4440", "evidence": [ { "id": "4440", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4440" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "cellular bud neck septin ring", "id": "GO:0000144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000144", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "outer plaque of spindle pole body", "id": "GO:0005824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005824", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "cellular bud neck", "id": "GO:0005935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005935", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "cellular bud neck septin collar", "id": "GO:0032174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032174", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "positive regulation of mitotic nuclear division", "id": "GO:0045840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045840", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "protein-arginine omega-N monomethyltransferase activity", "id": "GO:0035241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035241", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" }, { "name": "protein-arginine omega-N symmetric methyltransferase activity", "id": "GO:0035243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035243", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38274-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "315", "end_pos": "315", "site_lbl": "Ser315", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Ser317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Ser327", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Ser343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "24440502", "url": "https://glygen.org/publication/PubMed/24440502" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "611", "end_pos": "611", "site_lbl": "Ser611", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "614", "end_pos": "614", "site_lbl": "Thr614", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "618", "end_pos": "618", "site_lbl": "Thr618", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "702", "end_pos": "702", "site_lbl": "Ser702", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "705", "end_pos": "705", "site_lbl": "Thr705", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "708", "end_pos": "708", "site_lbl": "Thr708", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "718", "end_pos": "718", "site_lbl": "Ser718", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "720", "end_pos": "720", "site_lbl": "Thr720", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "753", "end_pos": "753", "site_lbl": "Ser753", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "11408575", "url": "https://glygen.org/publication/PubMed/11408575" }, { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "761", "end_pos": "761", "site_lbl": "Ser761", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "771", "end_pos": "771", "site_lbl": "Ser771", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "788", "end_pos": "788", "site_lbl": "Ser788", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000337", "url": "https://www.yeastgenome.org/locus/S000000337" }, { "database": "iPTMnet", "id": "P38274", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38274" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Gly387", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Almost completely abolishes catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" }, { "database": "PubMed", "id": "18515076", "url": "https://glygen.org/publication/PubMed/18515076" } ] }, { "sequence_org": "G", "sequence_mut": "V", "comment": "Completely abolishes catalytic activity; when associated with V-389.", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" }, { "database": "PubMed", "id": "18515076", "url": "https://glygen.org/publication/PubMed/18515076" } ] } ] }, { "uniprot_canonical_ac": "P38274-1", "start_pos": "389", "end_pos": "389", "site_lbl": "Gly389", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "V", "comment": "Completely abolishes catalytic activity; when associated with V-387.", "evidence": [ { "database": "UniProtKB", "id": "P38274", "url": "https://www.uniprot.org/uniprotkb/P38274" }, { "database": "PubMed", "id": "18515076", "url": "https://glygen.org/publication/PubMed/18515076" } ] } ] } ], "record_id": "P38274-1" }, { "uniprot_canonical_ac": "P38287-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 376, "chemical_mass": 44382.0, "gene_names": "CSH1;CSH1;YBR1212", "protein_name": "Mannosyl phosphorylinositol ceramide synthase CSH1", "disease": [], "cellular_component": [ { "name": "mannosyltransferase complex", "id": "GO:0031501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031501", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "pmid": "" }, { "name": "fungal-type vacuole", "id": "GO:0000324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000324", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "pmid": "" } ], "biological_process": [ { "name": "glycosphingolipid biosynthetic process", "id": "GO:0006688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006688", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "pmid": "" }, { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "pmid": "" }, { "name": "mannosyl diphosphorylinositol ceramide metabolic process", "id": "GO:0006676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006676", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "pmid": "" }, { "name": "mannosyl-inositol phosphorylceramide biosynthetic process", "id": "GO:0051999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051999", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "pmid": "" } ], "molecular_function": [ { "name": "mannosyltransferase activity", "id": "GO:0000030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000030", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "pmid": "" }, { "name": "inositol phosphorylceramide mannosyltransferase activity", "id": "GO:0103064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0103064", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38287-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Asn247", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "automatic_literature_mining", "site_category_dict": { "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 247, "start_aa": "Asn", "end_pos": 247, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn247", "evidence": [ { "id": "35713525", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35713525" }, { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "mining_tool": "GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "GlycoSiteMiner_1.0" } ] } ] }, { "uniprot_canonical_ac": "P38287-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Asn51", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "automatic_literature_mining", "site_category_dict": { "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Asn", "end_pos": 51, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn51", "evidence": [ { "id": "35713525", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35713525" }, { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "mining_tool": "GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "GlycoSiteMiner_1.0" } ] } ] }, { "uniprot_canonical_ac": "P38287-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Ser354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38287", "url": "https://www.uniprot.org/uniprotkb/P38287" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38287" }, { "database": "SGD", "id": "S000000365", "url": "https://www.yeastgenome.org/locus/S000000365" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38287-1" }, { "uniprot_canonical_ac": "P38297-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 855, "chemical_mass": 97808.0, "gene_names": "FZO1;FZO1;YBR1241", "protein_name": "Mitofusin FZO1", "disease": [ { "disease_id": "DOID:0050539", "name": "Charcot-Marie-Tooth disease type 2", "description": "A Charcot-Marie-Tooth disease characterized by abnormalities in the axon of the peripheral nerve cell.", "url": "https://disease-ontology.org/term/DOID:0050539", "evidence": [ { "id": "0050539", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050539" } ], "weight": 0.0 }, { "disease_id": "DOID:0080068", "name": "Charcot-Marie-Tooth disease type 6", "description": "A Charcot-Marie-Tooth disease that is characterized by early-onset optic atrophy resulting in progressive visual loss and peripheral axonal sensorimotor neuropathy with highly variable age at onset and severity.", "url": "https://disease-ontology.org/term/DOID:0080068", "evidence": [ { "id": "0080068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080068" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0110155", "name": "Charcot-Marie-Tooth disease type 2A2A", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in heterozygous mutation in the MFN2 gene on chromosome 1p36.22.", "url": "https://disease-ontology.org/term/DOID:0110155", "evidence": [ { "id": "0110155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110155" } ], "weight": 0.0 }, { "disease_id": "DOID:0111557", "name": "Charcot-Marie-Tooth disease type 2A2B", "description": "A Charcot-Marie-Tooth disease type 2 characterized by onset of peripheral neuropathy in the first years of life that has_material_basis_in homozygous or compound heterozygous mutation in the MFN2 gene on chromosome 1p36.22.", "url": "https://disease-ontology.org/term/DOID:0111557", "evidence": [ { "id": "0111557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111557" } ], "weight": 0.0 }, { "disease_id": "DOID:10595", "name": "Charcot-Marie-Tooth disease", "description": "A neuromuscular disease that is characterized by a slowly progressive degeneration of the muscles of the foot, lower leg, hand and forearm.", "url": "https://disease-ontology.org/term/DOID:10595", "evidence": [ { "id": "10595", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10595" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11394", "name": "adult respiratory distress syndrome", "description": "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.", "url": "https://disease-ontology.org/term/DOID:11394", "evidence": [ { "id": "11394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11394" } ], "weight": 0.0 }, { "disease_id": "DOID:11716", "name": "prediabetes syndrome", "description": "A glucose metabolism disease that is characterized by blood glucose levels are high, but not high enough to be classified as type 2 diabetes.", "url": "https://disease-ontology.org/term/DOID:11716", "evidence": [ { "id": "11716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11716" } ], "weight": 0.0 }, { "disease_id": "DOID:13001", "name": "carotid stenosis", "description": "", "url": "https://disease-ontology.org/term/DOID:13001", "evidence": [ { "id": "13001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13001" } ], "weight": 0.0 }, { "disease_id": "DOID:13711", "name": "dental fluorosis", "description": "A tooth disease characterized by enamel discoloration resulting from excess fluoride ingestion during tooth formation.", "url": "https://disease-ontology.org/term/DOID:13711", "evidence": [ { "id": "13711", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13711" } ], "weight": 0.0 }, { "disease_id": "DOID:14116", "name": "multiple symmetric lipomatosis", "description": "", "url": "https://disease-ontology.org/term/DOID:14116", "evidence": [ { "id": "14116", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14116" } ], "weight": 0.0 }, { "disease_id": "DOID:14557", "name": "primary pulmonary hypertension", "description": "A chronic pulmonary heart disease characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein, or pulmonary capillaries, among others, has symptoms shortness of breath, dizziness, fainting, leg swelling.", "url": "https://disease-ontology.org/term/DOID:14557", "evidence": [ { "id": "14557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14557" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.", "url": "https://disease-ontology.org/term/DOID:4483", "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6364", "name": "migraine", "description": "A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing.", "url": "https://disease-ontology.org/term/DOID:6364", "evidence": [ { "id": "6364", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6364" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" }, { "name": "peroxisome-mitochondrion membrane tether activity", "id": "GO:0160190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160190", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" }, { "name": "peroxisomal-mitochondrial contact site", "id": "GO:0160189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160189", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" }, { "name": "mitochondrion localization", "id": "GO:0051646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051646", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" }, { "name": "intracellular distribution of mitochondria", "id": "GO:0048312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048312", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" }, { "name": "mitochondrial outer membrane fusion", "id": "GO:1990626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990626", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" }, { "name": "mitochondrial inner membrane fusion", "id": "GO:1990627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990627", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38297-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000383", "url": "https://www.yeastgenome.org/locus/S000000383" }, { "database": "iPTMnet", "id": "P38297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000383", "url": "https://www.yeastgenome.org/locus/S000000383" }, { "database": "iPTMnet", "id": "P38297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38297" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Tyr436", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38297" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "437", "end_pos": "437", "site_lbl": "Ser437", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38297" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Ser438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38297" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Ser439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38297" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Ser78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000383", "url": "https://www.yeastgenome.org/locus/S000000383" }, { "database": "iPTMnet", "id": "P38297", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38297" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Val172", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "P", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Asp195", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "21385840", "url": "https://glygen.org/publication/PubMed/21385840" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Val196", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "M", "comment": "Leads to an unusual intermediate mitochondrial morphology described as disorganized tubules in which mitochondria are tubular, distorted, less branched, and poorly distributed throughout the cell.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "19812251", "url": "https://glygen.org/publication/PubMed/19812251" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Asn197", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "21385840", "url": "https://glygen.org/publication/PubMed/21385840" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Lys200", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Abolishes fusion function, MDM30-binding and MDM30-dependent ubiquitination. No effect on localization or interaction with UGO1.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" }, { "database": "PubMed", "id": "21502136", "url": "https://glygen.org/publication/PubMed/21502136" }, { "database": "PubMed", "id": "21385840", "url": "https://glygen.org/publication/PubMed/21385840" }, { "database": "PubMed", "id": "9786948", "url": "https://glygen.org/publication/PubMed/9786948" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] }, { "sequence_org": "K", "sequence_mut": "D", "comment": "Abolishes respiratory growth.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "N", "comment": "Abolishes fusion function, MDM30-binding and MDM30-dependent ubiquitination, but not localization to mitochondrial outer membrane.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" }, { "database": "PubMed", "id": "21502136", "url": "https://glygen.org/publication/PubMed/21502136" }, { "database": "PubMed", "id": "21385840", "url": "https://glygen.org/publication/PubMed/21385840" }, { "database": "PubMed", "id": "9786948", "url": "https://glygen.org/publication/PubMed/9786948" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Thr221", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes fusion function, MDM30-binding and MDM30-dependent ubiquitination, but not localization to mitochondrial outer membrane.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" }, { "database": "PubMed", "id": "21502136", "url": "https://glygen.org/publication/PubMed/21502136" }, { "database": "PubMed", "id": "21385840", "url": "https://glygen.org/publication/PubMed/21385840" }, { "database": "PubMed", "id": "9786948", "url": "https://glygen.org/publication/PubMed/9786948" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Asp313", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "K", "comment": "Abolishes respiratory growth.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Asp320", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of mitochondrial fusion.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "21385840", "url": "https://glygen.org/publication/PubMed/21385840" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "327", "end_pos": "327", "site_lbl": "Val327", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "T", "comment": "Impairs GTPHydrolysis and abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "19812251", "url": "https://glygen.org/publication/PubMed/19812251" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "335", "end_pos": "335", "site_lbl": "Asp335", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "K", "comment": "Abolishes respiratory growth. Restores respiratory growth; when associated with D-464.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Lys371", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "9786948", "url": "https://glygen.org/publication/PubMed/9786948" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Lys398", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Leads to accelerated proteolysis.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "23317502", "url": "https://glygen.org/publication/PubMed/23317502" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "464", "end_pos": "464", "site_lbl": "Lys464", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "D", "comment": "Abolishes respiratory growth. Restores respiratory growth; when associated with K-335.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "23317502", "url": "https://glygen.org/publication/PubMed/23317502" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Tyr490", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] }, { "sequence_org": "Y", "sequence_mut": "K", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] }, { "sequence_org": "Y", "sequence_mut": "P", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "501", "end_pos": "501", "site_lbl": "Leu501", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes fusion function; when associated with Ala-504.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Leu504", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes fusion function; when associated with Ala-501.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Leu518", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Asp523", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "H", "comment": "Abolishes respiratory growth. Restores respiratory growth; when associated with D-780.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "538", "end_pos": "538", "site_lbl": "Lys538", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "P", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "769", "end_pos": "769", "site_lbl": "Tyr769", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "P", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "773", "end_pos": "773", "site_lbl": "Leu773", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "780", "end_pos": "780", "site_lbl": "His780", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "D", "comment": "No effect. Restores respiratory growth; when associated with H-523.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "818", "end_pos": "818", "site_lbl": "Glu818", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] }, { "sequence_org": "E", "sequence_mut": "P", "comment": "Abolishes respiratory growth.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] }, { "sequence_org": "E", "sequence_mut": "R", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] } ] }, { "uniprot_canonical_ac": "P38297-1", "start_pos": "819", "end_pos": "819", "site_lbl": "Leu819", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] }, { "sequence_org": "L", "sequence_mut": "E", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] }, { "sequence_org": "L", "sequence_mut": "P", "comment": "Abolishes fusion function.", "evidence": [ { "database": "UniProtKB", "id": "P38297", "url": "https://www.uniprot.org/uniprotkb/P38297" }, { "database": "PubMed", "id": "16624808", "url": "https://glygen.org/publication/PubMed/16624808" }, { "database": "PubMed", "id": "28860650", "url": "https://glygen.org/publication/PubMed/28860650" } ] } ] } ], "record_id": "P38297-1" }, { "uniprot_canonical_ac": "P38302-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38302", "url": "https://www.uniprot.org/uniprotkb/P38302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 140, "chemical_mass": 15970.0, "gene_names": "NTC20;NTC20;SNT384;YBR1316", "protein_name": "Pre-mRNA-splicing factor NTC20", "disease": [], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "P38302", "url": "https://www.uniprot.org/uniprotkb/P38302" } ], "pmid": "" } ], "cellular_component": [ { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "P38302", "url": "https://www.uniprot.org/uniprotkb/P38302" } ], "pmid": "" }, { "name": "Prp19 complex", "id": "GO:0000974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000974", "evidence": [ { "database": "UniProtKB", "id": "P38302", "url": "https://www.uniprot.org/uniprotkb/P38302" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38302-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38302", "url": "https://www.uniprot.org/uniprotkb/P38302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38302" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000392", "url": "https://www.yeastgenome.org/locus/S000000392" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38302-1" }, { "uniprot_canonical_ac": "P38310-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 465, "chemical_mass": 51420.0, "gene_names": "FTH1;FTH1;YBR1446", "protein_name": "Iron transporter FTH1", "disease": [], "biological_process": [ { "name": "iron ion transmembrane transport", "id": "GO:0034755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034755", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "pmid": "" }, { "name": "high-affinity iron permease complex", "id": "GO:0033573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033573", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "pmid": "" } ], "molecular_function": [ { "name": "ferrous iron transmembrane transporter activity", "id": "GO:0015093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015093", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "pmid": "" }, { "name": "iron ion transmembrane transporter activity", "id": "GO:0005381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005381", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38310-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000411", "url": "https://www.yeastgenome.org/locus/S000000411" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Ser287", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "421", "end_pos": "421", "site_lbl": "Ser421", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000411", "url": "https://www.yeastgenome.org/locus/S000000411" }, { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Ser439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000411", "url": "https://www.yeastgenome.org/locus/S000000411" }, { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "440", "end_pos": "440", "site_lbl": "Thr440", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000411", "url": "https://www.yeastgenome.org/locus/S000000411" }, { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Ser441", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000411", "url": "https://www.yeastgenome.org/locus/S000000411" }, { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "445", "end_pos": "445", "site_lbl": "Ser445", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000411", "url": "https://www.yeastgenome.org/locus/S000000411" }, { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "449", "end_pos": "449", "site_lbl": "Ser449", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000411", "url": "https://www.yeastgenome.org/locus/S000000411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000411", "url": "https://www.yeastgenome.org/locus/S000000411" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "453", "end_pos": "453", "site_lbl": "Ser453", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38310", "url": "https://www.uniprot.org/uniprotkb/P38310" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "SGD", "id": "S000000411", "url": "https://www.yeastgenome.org/locus/S000000411" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38310-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Ser463", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000411", "url": "https://www.yeastgenome.org/locus/S000000411" }, { "database": "iPTMnet", "id": "P38310", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38310" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P38310-1" }, { "uniprot_canonical_ac": "P38328-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38328", "url": "https://www.uniprot.org/uniprotkb/P38328" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 384, "chemical_mass": 42475.0, "gene_names": "ARC40;ARC40;YBR1532", "protein_name": "Actin-related protein 2/3 complex subunit 1", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0112004", "name": "immunodeficiency 71", "description": "A combined immunodeficiency characterized by thrombocytopenia, impaired neutrophil and T-cell chemotaxis, impaired T-cell activation, and onset in infancy or early childhood of recurrent infections and inflammatory features that has_material_basis_in homozygous or compound heterozygous mutation in the ARPC1B gene on chromosome 7q22.1.", "url": "https://disease-ontology.org/term/DOID:0112004", "evidence": [ { "id": "0112004", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112004" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:4029", "name": "gastritis", "description": "A stomach disease that is an inflammation of the lining of the stomach.", "url": "https://disease-ontology.org/term/DOID:4029", "evidence": [ { "id": "4029", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4029" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "P38328", "url": "https://www.uniprot.org/uniprotkb/P38328" } ], "pmid": "" }, { "name": "Arp2/3 protein complex", "id": "GO:0005885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005885", "evidence": [ { "database": "UniProtKB", "id": "P38328", "url": "https://www.uniprot.org/uniprotkb/P38328" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P38328", "url": "https://www.uniprot.org/uniprotkb/P38328" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "P38328", "url": "https://www.uniprot.org/uniprotkb/P38328" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "P38328", "url": "https://www.uniprot.org/uniprotkb/P38328" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:2000601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000601", "evidence": [ { "database": "UniProtKB", "id": "P38328", "url": "https://www.uniprot.org/uniprotkb/P38328" } ], "pmid": "" }, { "name": "Arp2/3 complex-mediated actin nucleation", "id": "GO:0034314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314", "evidence": [ { "database": "UniProtKB", "id": "P38328", "url": "https://www.uniprot.org/uniprotkb/P38328" } ], "pmid": "" }, { "name": "actin nucleation", "id": "GO:0045010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045010", "evidence": [ { "database": "UniProtKB", "id": "P38328", "url": "https://www.uniprot.org/uniprotkb/P38328" } ], "pmid": "" }, { "name": "actin cortical patch organization", "id": "GO:0044396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044396", "evidence": [ { "database": "UniProtKB", "id": "P38328", "url": "https://www.uniprot.org/uniprotkb/P38328" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38328-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Ser10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000438", "url": "https://www.yeastgenome.org/locus/S000000438" }, { "database": "iPTMnet", "id": "P38328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38328" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38328-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000438", "url": "https://www.yeastgenome.org/locus/S000000438" }, { "database": "iPTMnet", "id": "P38328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38328" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38328-1", "start_pos": "323", "end_pos": "323", "site_lbl": "Thr323", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000438", "url": "https://www.yeastgenome.org/locus/S000000438" }, { "database": "iPTMnet", "id": "P38328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38328" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38328-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000438", "url": "https://www.yeastgenome.org/locus/S000000438" }, { "database": "iPTMnet", "id": "P38328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38328" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38328-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000438", "url": "https://www.yeastgenome.org/locus/S000000438" }, { "database": "iPTMnet", "id": "P38328", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38328" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38328-1" }, { "uniprot_canonical_ac": "P38334-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 175, "chemical_mass": 19700.0, "gene_names": "TRS20;TRS20;YBR1722", "protein_name": "Trafficking protein particle complex subunit 20", "disease": [ { "disease_id": "DOID:0080362", "name": "X-linked spondyloepiphyseal dysplasia tarda", "description": "A spondyloepiphyseal dysplasia that is characterized by impaired growth of bones of the spine and the ends of long bones in the arms and legs and has_material_basis_in mutation in the SEDL gene on chromosome Xp22.", "url": "https://disease-ontology.org/term/DOID:0080362", "evidence": [ { "id": "0080362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080362" } ], "weight": 0.0 }, { "disease_id": "DOID:14789", "name": "spondyloepiphyseal dysplasia congenita", "description": "A spondyloepiphyseal dysplasia characterized by disproportionate short stature (short trunk), abnormal epiphyses, and flattened vertebral bodies that has_material_basis_in heterozygous mutation in the COL2A1 gene on chromosome 12q13.11.", "url": "https://disease-ontology.org/term/DOID:14789", "evidence": [ { "id": "14789", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14789" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "TRAPPIII protein complex", "id": "GO:1990072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990072", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "TRAPPI protein complex", "id": "GO:1990070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990070", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "TRAPP complex", "id": "GO:0030008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030008", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "TRAPPII protein complex", "id": "GO:1990071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990071", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" } ], "biological_process": [ { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "P38334", "url": "https://www.uniprot.org/uniprotkb/P38334" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38334-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Ser158", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000458", "url": "https://www.yeastgenome.org/locus/S000000458" }, { "database": "iPTMnet", "id": "P38334", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38334" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38334-1" }, { "uniprot_canonical_ac": "P38353-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 490, "chemical_mass": 53312.0, "gene_names": "SSH1;SSH1;YBR2020", "protein_name": "Sec sixty-one protein homolog", "disease": [ { "disease_id": "DOID:0050590", "name": "severe congenital neutropenia", "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.", "url": "https://disease-ontology.org/term/DOID:0050590", "evidence": [ { "id": "0050590", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050590" } ], "weight": 0.0 }, { "disease_id": "DOID:0061120", "name": "autosomal dominant tubulointerstitial kidney disease 5", "description": "An autosomal dominant tubulointerstitial kidney disease characterized by the onset of progressive chronic renal disease in the first decades of life that has_material_basis_in heterozygous mutation in the SEC61A1 gene on chromosome 3q21.", "url": "https://disease-ontology.org/term/DOID:0061120", "evidence": [ { "id": "0061120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061120" } ], "weight": 0.0 }, { "disease_id": "DOID:12177", "name": "common variable immunodeficiency", "description": "An agammaglobulinemia that is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells and that results in insufficient production of antibodies needed to respond to exposure of pathogens.", "url": "https://disease-ontology.org/term/DOID:12177", "evidence": [ { "id": "12177", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12177" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "pmid": "" }, { "name": "Sec61 translocon complex", "id": "GO:0005784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005784", "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "pmid": "" }, { "name": "Ssh1 translocon complex", "id": "GO:0071261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071261", "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "pmid": "" } ], "molecular_function": [ { "name": "signal sequence binding", "id": "GO:0005048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005048", "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "pmid": "" }, { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "pmid": "" } ], "biological_process": [ { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "pmid": "" }, { "name": "post-translational protein targeting to membrane, translocation", "id": "GO:0031204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031204", "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, translocation", "id": "GO:0006616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006616", "evidence": [ { "database": "UniProtKB", "id": "P38353", "url": "https://www.uniprot.org/uniprotkb/P38353" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P38353-1" }, { "uniprot_canonical_ac": "P38426-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1054, "chemical_mass": 118835.0, "gene_names": "TPS3;TPS3;YM8156.03C", "protein_name": "Trehalose synthase complex regulatory subunit TPS3", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" } ], "pmid": "" }, { "name": "alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)", "id": "GO:0005946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005946", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" } ], "pmid": "" }, { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" } ], "pmid": "" } ], "biological_process": [ { "name": "trehalose biosynthetic process", "id": "GO:0005992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005992", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38426-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 148, "start_aa": "Ser", "end_pos": 148, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser148", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Ser150", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 150, "start_aa": "Ser", "end_pos": 150, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser150", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Ser154", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 154, "start_aa": "Ser", "end_pos": 154, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser154", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 156, "start_aa": "Ser", "end_pos": 156, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser156", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 157, "start_aa": "Ser", "end_pos": 157, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser157", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Ser159", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 159, "start_aa": "Ser", "end_pos": 159, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser159", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 161, "start_aa": "Ser", "end_pos": 161, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser161", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 195, "start_aa": "Ser", "end_pos": 195, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser195", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Ser202", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 202, "start_aa": "Ser", "end_pos": 202, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser202", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 235, "start_aa": "Ser", "end_pos": 235, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser235", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "237", "end_pos": "237", "site_lbl": "Ser237", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 237, "start_aa": "Ser", "end_pos": 237, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser237", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Thr238", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 238, "start_aa": "Thr", "end_pos": 238, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr238", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 242, "start_aa": "Ser", "end_pos": 242, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser242", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Ser243", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 243, "start_aa": "Ser", "end_pos": 243, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser243", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Ser246", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 246, "start_aa": "Ser", "end_pos": 246, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser246", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Ser247", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 247, "start_aa": "Ser", "end_pos": 247, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser247", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Ser248", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 248, "start_aa": "Ser", "end_pos": 248, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser248", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "249", "end_pos": "249", "site_lbl": "Ser249", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 249, "start_aa": "Ser", "end_pos": 249, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser249", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Ser51", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 51, "start_aa": "Ser", "end_pos": 51, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser51", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 52, "start_aa": "Ser", "end_pos": 52, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser52", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 53, "start_aa": "Ser", "end_pos": 53, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser53", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Thr55", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 56, "start_aa": "Ser", "end_pos": 56, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser56", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 58, "start_aa": "Ser", "end_pos": 58, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser58", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Ser59", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 59, "start_aa": "Ser", "end_pos": 59, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser59", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "973", "end_pos": "973", "site_lbl": "Ser973", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 973, "start_aa": "Ser", "end_pos": 973, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser973", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "974", "end_pos": "974", "site_lbl": "Ser974", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 974, "start_aa": "Ser", "end_pos": 974, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser974", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "975", "end_pos": "975", "site_lbl": "Ser975", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 975, "start_aa": "Ser", "end_pos": 975, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser975", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "977", "end_pos": "977", "site_lbl": "Ser977", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 977, "start_aa": "Ser", "end_pos": 977, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser977", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38426", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38426" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Thr199", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Tyr253", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Ser254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Thr265", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Ser273", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Ser292", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Ser300", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Ser305", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Tyr61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "700", "end_pos": "700", "site_lbl": "Thr700", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "732", "end_pos": "732", "site_lbl": "Ser732", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Ser82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "957", "end_pos": "957", "site_lbl": "Ser957", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "960", "end_pos": "960", "site_lbl": "Ser960", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38426", "url": "https://www.uniprot.org/uniprotkb/P38426" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "962", "end_pos": "962", "site_lbl": "Thr962", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "965", "end_pos": "965", "site_lbl": "Ser965", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "968", "end_pos": "968", "site_lbl": "Ser968", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "970", "end_pos": "970", "site_lbl": "Ser970", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38426-1", "start_pos": "972", "end_pos": "972", "site_lbl": "Thr972", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38426", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38426" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004874", "url": "https://www.yeastgenome.org/locus/S000004874" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P38426-1" }, { "uniprot_canonical_ac": "P38427-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1098, "chemical_mass": 123018.0, "gene_names": "TSL1;TSL1", "protein_name": "Trehalose synthase complex regulatory subunit TSL1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" } ], "pmid": "" }, { "name": "alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)", "id": "GO:0005946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005946", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" } ], "pmid": "" } ], "molecular_function": [ { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" } ], "pmid": "" } ], "biological_process": [ { "name": "trehalose biosynthetic process", "id": "GO:0005992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005992", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38427-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 181, "start_aa": "Ser", "end_pos": 181, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser181", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38427", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38427" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 186, "start_aa": "Ser", "end_pos": 186, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser186", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38427", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38427" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Ser192", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 192, "start_aa": "Ser", "end_pos": 192, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser192", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38427", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38427" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Ser195", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 195, "start_aa": "Ser", "end_pos": 195, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser195", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38427", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38427" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 216, "start_aa": "Ser", "end_pos": 216, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser216", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38427", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38427" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 220, "start_aa": "Ser", "end_pos": 220, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser220", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38427", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38427" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "1025", "end_pos": "1025", "site_lbl": "Ser1025", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "1042", "end_pos": "1042", "site_lbl": "Ser1042", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "1043", "end_pos": "1043", "site_lbl": "Ser1043", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "1058", "end_pos": "1058", "site_lbl": "Ser1058", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "1075", "end_pos": "1075", "site_lbl": "Ser1075", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "1076", "end_pos": "1076", "site_lbl": "Thr1076", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Thr111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Thr115", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Ser129", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "23273919", "url": "https://glygen.org/publication/PubMed/23273919" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Ser155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "157", "end_pos": "157", "site_lbl": "Ser157", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Ser161", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Thr191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Thr247", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Thr251", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Ser253", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Ser266", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Ser283", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Ser288", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "303", "end_pos": "303", "site_lbl": "Ser303", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "323", "end_pos": "323", "site_lbl": "Ser323", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Ser336", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Ser337", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "49", "end_pos": "49", "site_lbl": "Ser49", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Ser56", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Ser640", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ser77", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23273919", "url": "https://glygen.org/publication/PubMed/23273919" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "815", "end_pos": "815", "site_lbl": "Thr815", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38427", "url": "https://www.uniprot.org/uniprotkb/P38427" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "817", "end_pos": "817", "site_lbl": "Thr817", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38427-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Ser86", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004566", "url": "https://www.yeastgenome.org/locus/S000004566" }, { "database": "iPTMnet", "id": "P38427", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38427" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38427-1" }, { "uniprot_canonical_ac": "P38623-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 610, "chemical_mass": 68062.0, "gene_names": "RCK2;CLK1;CMK3;L9672.6;RCK2", "protein_name": "Serine/threonine-protein kinase RCK2", "disease": [ { "disease_id": "DOID:0061033", "name": "autosomal dominant intellectual developmental disorder 59", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the CAMK2G gene on chromosome 10q22.", "url": "https://disease-ontology.org/term/DOID:0061033", "evidence": [ { "id": "0061033", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061033" } ], "weight": 0.0 }, { "disease_id": "DOID:0080228", "name": "autosomal dominant intellectual developmental disorder 53", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the CAMK2A gene on chromosome 5q32.", "url": "https://disease-ontology.org/term/DOID:0080228", "evidence": [ { "id": "0080228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080228" } ], "weight": 0.0 }, { "disease_id": "DOID:0080230", "name": "autosomal dominant intellectual developmental disorder 54", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the CAMK2B gene on chromosome 7p13.", "url": "https://disease-ontology.org/term/DOID:0080230", "evidence": [ { "id": "0080230", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080230" } ], "weight": 0.0 }, { "disease_id": "DOID:0081224", "name": "autosomal recessive intellectual developmental disorder 63", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the CAMK2A gene on chromosome 5q32.", "url": "https://disease-ontology.org/term/DOID:0081224", "evidence": [ { "id": "0081224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081224" } ], "weight": 0.0 }, { "disease_id": "DOID:10273", "name": "heart conduction disease", "description": "A cardiovascular system disease that involves the heart's electrical conduction system.", "url": "https://disease-ontology.org/term/DOID:10273", "evidence": [ { "id": "10273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10273" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:3069", "name": "malignant astrocytoma", "description": "A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord.", "url": "https://disease-ontology.org/term/DOID:3069", "evidence": [ { "id": "3069", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3069" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 } ], "biological_process": [ { "name": "osmosensory signaling pathway", "id": "GO:0007231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007231", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "pmid": "" }, { "name": "regulation of meiotic nuclear division", "id": "GO:0040020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040020", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38623-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Thr601", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 601, "start_aa": "Thr", "end_pos": 601, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr601", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Ser22", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Ser33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Thr35", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "379", "end_pos": "379", "site_lbl": "Thr379", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "11344302", "url": "https://glygen.org/publication/PubMed/11344302" }, { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Thr44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Ser50", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Ser515", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "516", "end_pos": "516", "site_lbl": "Ser516", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "520", "end_pos": "520", "site_lbl": "Ser520", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38623", "url": "https://www.uniprot.org/uniprotkb/P38623" }, { "database": "PubMed", "id": "10805732", "url": "https://glygen.org/publication/PubMed/10805732" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "11344302", "url": "https://glygen.org/publication/PubMed/11344302" }, { "database": "PubMed", "id": "14735355", "url": "https://glygen.org/publication/PubMed/14735355" }, { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Ser564", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "605", "end_pos": "605", "site_lbl": "Ser605", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38623-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004238", "url": "https://www.yeastgenome.org/locus/S000004238" }, { "database": "iPTMnet", "id": "P38623", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38623" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38623-1" }, { "uniprot_canonical_ac": "P38629-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 340, "chemical_mass": 38204.0, "gene_names": "RFC3;N0533;RFC3", "protein_name": "Replication factor C subunit 3", "disease": [ { "disease_id": "DOID:1928", "name": "Williams-Beuren syndrome", "description": "A syndrome that is characterized by mild to moderate intellectual disability, a broad forehead, a short nose with a broad tip, full cheeks, and a wide mouth with full lips and difficulty with visual-spatial tasks and has_material_basis_in hemizygous deletion of 1.5 to 1.8 Mb on chromosome 7q11.23.", "url": "https://disease-ontology.org/term/DOID:1928", "evidence": [ { "id": "1928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1928" } ], "weight": 0.0 } ], "biological_process": [ { "name": "leading strand elongation", "id": "GO:0006272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006272", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "mismatch repair", "id": "GO:0006298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006298", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "Ctf18 RFC-like complex", "id": "GO:0031390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031390", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "Elg1 RFC-like complex", "id": "GO:0031391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031391", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "DNA replication factor C complex", "id": "GO:0005663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005663", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" }, { "name": "Rad17 RFC-like complex", "id": "GO:0031389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031389", "evidence": [ { "database": "UniProtKB", "id": "P38629", "url": "https://www.uniprot.org/uniprotkb/P38629" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38629-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Ser201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005234", "url": "https://www.yeastgenome.org/locus/S000005234" }, { "database": "iPTMnet", "id": "P38629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38629" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38629-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005234", "url": "https://www.yeastgenome.org/locus/S000005234" }, { "database": "iPTMnet", "id": "P38629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38629" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38629-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005234", "url": "https://www.yeastgenome.org/locus/S000005234" }, { "database": "iPTMnet", "id": "P38629", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38629" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38629-1" }, { "uniprot_canonical_ac": "P38633-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 127, "chemical_mass": 14741.0, "gene_names": "SOH1;G2864;MED31;SOH1", "protein_name": "Mediator of RNA polymerase II transcription subunit 31", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" }, { "name": "meiotic gene conversion", "id": "GO:0006311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006311", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "P38633", "url": "https://www.uniprot.org/uniprotkb/P38633" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38633-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Thr11", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11, "start_aa": "Thr", "end_pos": 11, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003095", "url": "https://www.yeastgenome.org/locus/S000003095" }, { "database": "iPTMnet", "id": "P38633", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38633" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38633-1" }, { "uniprot_canonical_ac": "P38689-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38689", "url": "https://www.uniprot.org/uniprotkb/P38689" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 320, "chemical_mass": 35124.0, "gene_names": "PRS3;PRPS3;PRS3", "protein_name": "Ribose-phosphate pyrophosphokinase 3", "disease": [ { "disease_id": "DOID:0050647", "name": "Arts syndrome", "description": "An X-linked disease that is characterized by profound congenital sensorineural hearing impairment, early-onset hypotonia, delayed motor development, mild to moderate intellectual disability, ataxia, and increased risk of infection and has_material_basis_in mutations of the PRPS1 gene.", "url": "https://disease-ontology.org/term/DOID:0050647", "evidence": [ { "id": "0050647", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050647" } ], "weight": 0.0 }, { "disease_id": "DOID:0110210", "name": "Charcot-Marie-Tooth disease X-linked recessive 5", "description": "A Charcot-Marie-Tooth disease X-linked that has_material_basis_in loss-of-function mutation in the PRPS1 gene on chromosome Xq22.", "url": "https://disease-ontology.org/term/DOID:0110210", "evidence": [ { "id": "0110210", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110210" } ], "weight": 0.0 }, { "disease_id": "DOID:0111260", "name": "phosphoribosylpyrophosphate synthetase superactivity", "description": "An inherited metabolic disorder characterized by increased synthesis of phosphoribosylpyrophosphate resulting in increased production of uric acid and purine that has_material_basis_in X-linked recessive inheritance of mutations in PRPS1 on Xq22.3 that result in increased activity of the gene. The mild form of the disease has late-juvenile or early adult onset while the more severe form has infantile or early-childhood onset.", "url": "https://disease-ontology.org/term/DOID:0111260", "evidence": [ { "id": "0111260", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111260" } ], "weight": 0.0 }, { "disease_id": "DOID:0111739", "name": "X-linked deafness 1", "description": "An X-linked nonsyndromic deafness characterized by congenital profound sensorineural hearing loss in males and mild to moderate high-frequency hearing loss in heterozygous females that has_material_basis_in mutation in the PRPS1 gene on chromosome Xq22.3.", "url": "https://disease-ontology.org/term/DOID:0111739", "evidence": [ { "id": "0111739", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111739" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:13189", "name": "gout", "description": "An arthritis that has_material_basis_in uric acid crystal deposits located_in joint.", "url": "https://disease-ontology.org/term/DOID:13189", "evidence": [ { "id": "13189", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13189" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ribose phosphate diphosphokinase complex", "id": "GO:0002189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002189", "evidence": [ { "database": "UniProtKB", "id": "P38689", "url": "https://www.uniprot.org/uniprotkb/P38689" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38689", "url": "https://www.uniprot.org/uniprotkb/P38689" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "P38689", "url": "https://www.uniprot.org/uniprotkb/P38689" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38689", "url": "https://www.uniprot.org/uniprotkb/P38689" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "P38689", "url": "https://www.uniprot.org/uniprotkb/P38689" } ], "pmid": "" }, { "name": "ribose phosphate diphosphokinase activity", "id": "GO:0004749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004749", "evidence": [ { "database": "UniProtKB", "id": "P38689", "url": "https://www.uniprot.org/uniprotkb/P38689" } ], "pmid": "" } ], "biological_process": [ { "name": "ribonucleoside monophosphate biosynthetic process", "id": "GO:0009156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009156", "evidence": [ { "database": "UniProtKB", "id": "P38689", "url": "https://www.uniprot.org/uniprotkb/P38689" } ], "pmid": "" }, { "name": "5-phosphoribose 1-diphosphate biosynthetic process", "id": "GO:0006015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006015", "evidence": [ { "database": "UniProtKB", "id": "P38689", "url": "https://www.uniprot.org/uniprotkb/P38689" } ], "pmid": "" }, { "name": "purine nucleotide biosynthetic process", "id": "GO:0006164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006164", "evidence": [ { "database": "UniProtKB", "id": "P38689", "url": "https://www.uniprot.org/uniprotkb/P38689" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38689-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Ser310", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001003", "url": "https://www.yeastgenome.org/locus/S000001003" }, { "database": "iPTMnet", "id": "P38689", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38689" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38689-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Ser312", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001003", "url": "https://www.yeastgenome.org/locus/S000001003" }, { "database": "iPTMnet", "id": "P38689", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38689" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38689-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Tyr313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001003", "url": "https://www.yeastgenome.org/locus/S000001003" }, { "database": "iPTMnet", "id": "P38689", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38689" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38689-1" }, { "uniprot_canonical_ac": "P38691-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1029, "chemical_mass": 117082.0, "gene_names": "KSP1;KSP1", "protein_name": "Serine/threonine-protein kinase KSP1", "disease": [], "biological_process": [ { "name": "regulation of translation in response to stress", "id": "GO:0043555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043555", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "TOR signaling", "id": "GO:0031929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031929", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "negative regulation of macroautophagy", "id": "GO:0016242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016242", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "regulation of filamentous growth", "id": "GO:0010570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010570", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "regulation of pseudohyphal growth", "id": "GO:2000220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000220", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38691-1", "start_pos": "784", "end_pos": "784", "site_lbl": "Ser784", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 784, "start_aa": "Ser", "end_pos": 784, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser784", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38691", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38691" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "787", "end_pos": "787", "site_lbl": "Ser787", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 787, "start_aa": "Ser", "end_pos": 787, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser787", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38691", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38691" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "788", "end_pos": "788", "site_lbl": "Ser788", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 788, "start_aa": "Ser", "end_pos": 788, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser788", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38691", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38691" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "795", "end_pos": "795", "site_lbl": "Ser795", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 795, "start_aa": "Ser", "end_pos": 795, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser795", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38691", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38691" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "796", "end_pos": "796", "site_lbl": "Ser796", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 796, "start_aa": "Ser", "end_pos": 796, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser796", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P38691", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P38691" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "1005", "end_pos": "1005", "site_lbl": "Thr1005", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "1006", "end_pos": "1006", "site_lbl": "Ser1006", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "1014", "end_pos": "1014", "site_lbl": "Ser1014", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Ser117", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Ser121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "416", "end_pos": "416", "site_lbl": "Ser416", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Ser419", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Ser426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "476", "end_pos": "476", "site_lbl": "Ser476", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Ser487", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "501", "end_pos": "501", "site_lbl": "Thr501", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Thr504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "526", "end_pos": "526", "site_lbl": "Thr526", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Ser529", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "29438499", "url": "https://glygen.org/publication/PubMed/29438499" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Ser539", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "552", "end_pos": "552", "site_lbl": "Tyr552", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "559", "end_pos": "559", "site_lbl": "Ser559", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "565", "end_pos": "565", "site_lbl": "Ser565", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Ser575", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "576", "end_pos": "576", "site_lbl": "Tyr576", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "591", "end_pos": "591", "site_lbl": "Ser591", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "22447937", "url": "https://glygen.org/publication/PubMed/22447937" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "592", "end_pos": "592", "site_lbl": "Ser592", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "593", "end_pos": "593", "site_lbl": "Ser593", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "594", "end_pos": "594", "site_lbl": "Ser594", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "595", "end_pos": "595", "site_lbl": "Tyr595", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Thr596", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Ser599", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "602", "end_pos": "602", "site_lbl": "Ser602", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "615", "end_pos": "615", "site_lbl": "Ser615", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "624", "end_pos": "624", "site_lbl": "Ser624", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "29438499", "url": "https://glygen.org/publication/PubMed/29438499" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "22447937", "url": "https://glygen.org/publication/PubMed/22447937" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Thr626", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "627", "end_pos": "627", "site_lbl": "Thr627", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "631", "end_pos": "631", "site_lbl": "Ser631", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "635", "end_pos": "635", "site_lbl": "Tyr635", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "646", "end_pos": "646", "site_lbl": "Ser646", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "657", "end_pos": "657", "site_lbl": "Ser657", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "658", "end_pos": "658", "site_lbl": "Thr658", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "814", "end_pos": "814", "site_lbl": "Ser814", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "PubMed", "id": "29438499", "url": "https://glygen.org/publication/PubMed/29438499" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "815", "end_pos": "815", "site_lbl": "Ser815", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "817", "end_pos": "817", "site_lbl": "Ser817", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "827", "end_pos": "827", "site_lbl": "Ser827", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "22447937", "url": "https://glygen.org/publication/PubMed/22447937" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "845", "end_pos": "845", "site_lbl": "Ser845", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "850", "end_pos": "850", "site_lbl": "Thr850", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "871", "end_pos": "871", "site_lbl": "Ser871", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "883", "end_pos": "883", "site_lbl": "Ser883", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "884", "end_pos": "884", "site_lbl": "Ser884", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38691", "url": "https://www.uniprot.org/uniprotkb/P38691" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "22447937", "url": "https://glygen.org/publication/PubMed/22447937" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "888", "end_pos": "888", "site_lbl": "Ser888", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "902", "end_pos": "902", "site_lbl": "Ser902", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "903", "end_pos": "903", "site_lbl": "Ser903", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "908", "end_pos": "908", "site_lbl": "Ser908", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "909", "end_pos": "909", "site_lbl": "Ser909", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "954", "end_pos": "954", "site_lbl": "Ser954", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "969", "end_pos": "969", "site_lbl": "Ser969", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "970", "end_pos": "970", "site_lbl": "Ser970", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "971", "end_pos": "971", "site_lbl": "Ser971", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "972", "end_pos": "972", "site_lbl": "Thr972", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "973", "end_pos": "973", "site_lbl": "Ser973", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38691-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Ser99", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38691", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38691" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001124", "url": "https://www.yeastgenome.org/locus/S000001124" } ] } ] } ], "record_id": "P38691-1" }, { "uniprot_canonical_ac": "P38696-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 384, "chemical_mass": 42995.0, "gene_names": "ARP1;ACT3;ACT5;ARP1", "protein_name": "Centractin", "disease": [ { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "pmid": "" }, { "name": "dynactin complex", "id": "GO:0005869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005869", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "pmid": "" }, { "name": "mitotic spindle orientation checkpoint signaling", "id": "GO:0031578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031578", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38696-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Glu133", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Lethal. Strongly reduces interaction with JNM1; when associated with A-136.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Asp136", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Lethal. Strongly reduces interaction with JNM1; when associated with A-133.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Asp162", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduces spindle formation. Reduces nuclear migration in mitosis; when associated with A-165.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Glu165", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Reduces spindle formation. Reduces nuclear migration in mitosis; when associated with A-162.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Arg185", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Temperature-sensitive. Strongly reduces interaction with JNM1; when associated with A-187.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Asp187", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Temperature-sensitive. Strongly reduces interaction with JNM1; when associated with A-185.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Arg219", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Lethal; when associated with 214-A--A-216.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Lys251", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Lethal and dominant cold-sensitive. Reduces nuclear migration in mitosis; when associated with A-254.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Asp254", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Lethal and dominant cold-sensitive. Reduces nuclear migration in mitosis; when associated with A-251.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Arg266", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Lethal. Reduces spindle formation. Reduces nuclear migration in mitosis; when associated with A-269.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Glu269", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Lethal. Reduces spindle formation. Reduces nuclear migration in mitosis; when associated with A-266.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Lys294", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Reduces nuclear migration in mitosis; when associated with A-296 and A-298.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Asp296", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduces nuclear migration in mitosis; when associated with A-294 and A-298.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Asp298", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduces nuclear migration in mitosis; when associated with A-294 and A-296.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Asp2", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Temperature-sensitive; when associated with A-6.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "326", "end_pos": "326", "site_lbl": "Asp326", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Temperature-sensitive. Reduces nuclear migration in mitosis. Strongly reduces interaction with JNM1; when associated with A-328.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Glu328", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Temperature-sensitive. Reduces nuclear migration in mitosis. Strongly reduces interaction with JNM1; when associated with A-326.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Lys336", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Strongly reduces interaction with JNM1; when associated with A-338.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Lys338", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Strongly reduces interaction with JNM1; when associated with A-336.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Lys369", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Lethal. Strongly reduces interaction with JNM1; when associated with A-371.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Asp371", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "AA", "comment": "Reduces nuclear migration in mitosis; when associated with 368-A-A-369.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] }, { "sequence_org": "D", "sequence_mut": "A", "comment": "Lethal. Strongly reduces interaction with JNM1; when associated with A-369.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "378", "end_pos": "378", "site_lbl": "Arg378", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Temperature-sensitive. Reduces nuclear migration in mitosis. Strongly reduces interaction with JNM1; when associated with 374-A-A-375.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Lys46", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Strongly reduces interaction with JNM1. Reduces nuclear migration in mitosis; when associated with 48-A-A-49.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Asp6", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Temperature-sensitive; when associated with A-2.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "15975903", "url": "https://glygen.org/publication/PubMed/15975903" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Lys73", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Reduces spindle formation; when associated with A-75.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Arg75", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces spindle formation; when associated with A-73.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" } ] } ] }, { "uniprot_canonical_ac": "P38696-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Asp87", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduces spindle formation. Reduces nuclear migration in mitosis; when associated with 84-A-A-85.", "evidence": [ { "database": "UniProtKB", "id": "P38696", "url": "https://www.uniprot.org/uniprotkb/P38696" }, { "database": "PubMed", "id": "16415535", "url": "https://glygen.org/publication/PubMed/16415535" } ] } ] } ], "record_id": "P38696-1" }, { "uniprot_canonical_ac": "P38700-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 605, "chemical_mass": 69990.0, "gene_names": "APM2;APM2", "protein_name": "Adaptin medium chain homolog APM2", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" }, { "name": "vesicle targeting, trans-Golgi to endosome", "id": "GO:0048203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048203", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" } ], "molecular_function": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38700-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Thr551", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 551, "start_aa": "Thr", "end_pos": 551, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr551", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P38700-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Ser352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001011", "url": "https://www.yeastgenome.org/locus/S000001011" }, { "database": "iPTMnet", "id": "P38700", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38700" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38700-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Phe273", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Leads to sensitivity to sertraline, when associated with S-275.", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" }, { "database": "PubMed", "id": "26658609", "url": "https://glygen.org/publication/PubMed/26658609" } ] } ] }, { "uniprot_canonical_ac": "P38700-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Asp275", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "S", "comment": "Leads to sensitivity to sertraline, when associated with A-273.", "evidence": [ { "database": "UniProtKB", "id": "P38700", "url": "https://www.uniprot.org/uniprotkb/P38700" }, { "database": "PubMed", "id": "26658609", "url": "https://glygen.org/publication/PubMed/26658609" } ] } ] } ], "record_id": "P38700-1" }, { "uniprot_canonical_ac": "P38703-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38703", "url": "https://www.uniprot.org/uniprotkb/P38703" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 411, "chemical_mass": 48455.0, "gene_names": "LAG1;LAG1", "protein_name": "Ceramide synthase LAG1", "disease": [ { "disease_id": "DOID:0060718", "name": "autosomal recessive congenital ichthyosis 9", "description": "An autosomal recessive congenital ichthyosis characterized by fine erythrodermic scales, palmoplantar hyperlinearity, thick orthohyperkeratosis, hypergranulosis, moderate acanthosis and mild alopecia that has_material_basis_in homozygous mutation in the CERS3 gene on chromosome 15q26.", "url": "https://disease-ontology.org/term/DOID:0060718", "evidence": [ { "id": "0060718", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060718" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P38703", "url": "https://www.uniprot.org/uniprotkb/P38703" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P38703", "url": "https://www.uniprot.org/uniprotkb/P38703" } ], "pmid": "" }, { "name": "acyl-CoA ceramide synthase complex", "id": "GO:0061576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061576", "evidence": [ { "database": "UniProtKB", "id": "P38703", "url": "https://www.uniprot.org/uniprotkb/P38703" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "P38703", "url": "https://www.uniprot.org/uniprotkb/P38703" } ], "pmid": "" } ], "molecular_function": [ { "name": "sphingosine N-acyltransferase activity", "id": "GO:0050291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050291", "evidence": [ { "database": "UniProtKB", "id": "P38703", "url": "https://www.uniprot.org/uniprotkb/P38703" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38703-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Asn103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 103, "start_aa": "Asn", "end_pos": 103, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn103", "evidence": [ { "id": "P38703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38703#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P38703-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38703", "url": "https://www.uniprot.org/uniprotkb/P38703" }, { "database": "PubMed", "id": "34492164", "url": "https://glygen.org/publication/PubMed/34492164" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38703" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000995", "url": "https://www.yeastgenome.org/locus/S000000995" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38703-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Ser24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38703", "url": "https://www.uniprot.org/uniprotkb/P38703" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "34492164", "url": "https://glygen.org/publication/PubMed/34492164" }, { "database": "iPTMnet", "id": "P38703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38703" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000995", "url": "https://www.yeastgenome.org/locus/S000000995" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38703-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000995", "url": "https://www.yeastgenome.org/locus/S000000995" }, { "database": "iPTMnet", "id": "P38703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38703" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38703-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38703" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000995", "url": "https://www.yeastgenome.org/locus/S000000995" } ] } ] }, { "uniprot_canonical_ac": "P38703-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000000995", "url": "https://www.yeastgenome.org/locus/S000000995" }, { "database": "iPTMnet", "id": "P38703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38703" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38703-1" }, { "uniprot_canonical_ac": "P38713-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 996, "chemical_mass": 113760.0, "gene_names": "OSH3;OSH3", "protein_name": "Oxysterol-binding protein homolog 3", "disease": [ { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "cortical endoplasmic reticulum", "id": "GO:0032541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032541", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "maintenance of cell polarity", "id": "GO:0030011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030011", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "ER to Golgi ceramide transport", "id": "GO:0035621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035621", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "sterol transport", "id": "GO:0015918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015918", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "karyogamy involved in conjugation with cellular fusion", "id": "GO:0000742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000742", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "invasive growth in response to glucose limitation", "id": "GO:0001403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001403", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "pseudohyphal growth", "id": "GO:0007124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007124", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "sterol binding", "id": "GO:0032934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032934", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" }, { "name": "sterol transfer activity", "id": "GO:0120015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120015", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38713-1", "start_pos": "766", "end_pos": "766", "site_lbl": "Thr766", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 766, "start_aa": "Thr", "end_pos": 766, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr766", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Ser106", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Tyr107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Ser108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "109", "end_pos": "109", "site_lbl": "Ser109", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Ser111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Ser190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Ser193", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Thr197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Thr203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Ser206", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Thr208", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Ser209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Thr210", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "323", "end_pos": "323", "site_lbl": "Thr323", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Ser324", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Thr325", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Ser343", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Ser344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Thr352", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Thr354", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Thr356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Ser359", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "362", "end_pos": "362", "site_lbl": "Ser362", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "422", "end_pos": "422", "site_lbl": "Thr422", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Ser424", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Ser426", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "427", "end_pos": "427", "site_lbl": "Ser427", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Thr430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "446", "end_pos": "446", "site_lbl": "Ser446", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "449", "end_pos": "449", "site_lbl": "Ser449", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Ser452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Ser504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Ser52", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "532", "end_pos": "532", "site_lbl": "Thr532", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "543", "end_pos": "543", "site_lbl": "Thr543", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "561", "end_pos": "561", "site_lbl": "Ser561", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "573", "end_pos": "573", "site_lbl": "Ser573", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "582", "end_pos": "582", "site_lbl": "Ser582", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "603", "end_pos": "603", "site_lbl": "Thr603", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "605", "end_pos": "605", "site_lbl": "Ser605", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38713", "url": "https://www.uniprot.org/uniprotkb/P38713" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "608", "end_pos": "608", "site_lbl": "Ser608", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "609", "end_pos": "609", "site_lbl": "Ser609", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Thr610", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "612", "end_pos": "612", "site_lbl": "Thr612", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Thr62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Thr67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Thr68", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Ser76", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" }, { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38713-1", "start_pos": "830", "end_pos": "830", "site_lbl": "Ser830", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38713", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38713" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001115", "url": "https://www.yeastgenome.org/locus/S000001115" } ] } ] } ], "record_id": "P38713-1" }, { "uniprot_canonical_ac": "P38719-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 431, "chemical_mass": 47878.0, "gene_names": "DBP8;DBP8", "protein_name": "ATP-dependent RNA helicase DBP8", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" } ], "biological_process": [ { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38719-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Asp155", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Decreases ATPase activity in vitro.", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" }, { "database": "PubMed", "id": "16772403", "url": "https://glygen.org/publication/PubMed/16772403" } ] } ] }, { "uniprot_canonical_ac": "P38719-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Lys52", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Decreases ATPase activity in vitro.", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" }, { "database": "PubMed", "id": "16772403", "url": "https://glygen.org/publication/PubMed/16772403" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Decreases ATPase activity in vitro.", "evidence": [ { "database": "UniProtKB", "id": "P38719", "url": "https://www.uniprot.org/uniprotkb/P38719" }, { "database": "PubMed", "id": "16772403", "url": "https://glygen.org/publication/PubMed/16772403" } ] } ] } ], "record_id": "P38719-1" }, { "uniprot_canonical_ac": "P38759-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38759", "url": "https://www.uniprot.org/uniprotkb/P38759" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 282, "chemical_mass": 31013.0, "gene_names": "VPS29;PEP11;VPS29;VPT6;VTP6", "protein_name": "Vacuolar protein sorting-associated protein 29", "disease": [], "cellular_component": [ { "name": "retromer, cargo-selective complex", "id": "GO:0030906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030906", "evidence": [ { "database": "UniProtKB", "id": "P38759", "url": "https://www.uniprot.org/uniprotkb/P38759" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "P38759", "url": "https://www.uniprot.org/uniprotkb/P38759" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38759", "url": "https://www.uniprot.org/uniprotkb/P38759" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "P38759", "url": "https://www.uniprot.org/uniprotkb/P38759" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "P38759", "url": "https://www.uniprot.org/uniprotkb/P38759" } ], "pmid": "" }, { "name": "CROP complex", "id": "GO:0170071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170071", "evidence": [ { "database": "UniProtKB", "id": "P38759", "url": "https://www.uniprot.org/uniprotkb/P38759" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P38759", "url": "https://www.uniprot.org/uniprotkb/P38759" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "P38759", "url": "https://www.uniprot.org/uniprotkb/P38759" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "P38759", "url": "https://www.uniprot.org/uniprotkb/P38759" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38759-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001054", "url": "https://www.yeastgenome.org/locus/S000001054" }, { "database": "iPTMnet", "id": "P38759", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38759" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38759-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001054", "url": "https://www.yeastgenome.org/locus/S000001054" }, { "database": "iPTMnet", "id": "P38759", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38759" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38759-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38759", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38759" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001054", "url": "https://www.yeastgenome.org/locus/S000001054" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38759-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001054", "url": "https://www.yeastgenome.org/locus/S000001054" }, { "database": "iPTMnet", "id": "P38759", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38759" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38759-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38759", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38759" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001054", "url": "https://www.yeastgenome.org/locus/S000001054" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38759-1", "start_pos": "207", "end_pos": "207", "site_lbl": "Thr207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001054", "url": "https://www.yeastgenome.org/locus/S000001054" }, { "database": "iPTMnet", "id": "P38759", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38759" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38759-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Ser238", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001054", "url": "https://www.yeastgenome.org/locus/S000001054" }, { "database": "iPTMnet", "id": "P38759", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38759" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38759-1" }, { "uniprot_canonical_ac": "P38764-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 993, "chemical_mass": 109492.0, "gene_names": "RPN1;HRD2;NAS1;RPD1;RPN1", "protein_name": "26S proteasome regulatory subunit RPN1", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "proteasome storage granule", "id": "GO:0034515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034515", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "pmid": "" }, { "name": "proteasome regulatory particle, base subcomplex", "id": "GO:0008540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008540", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "pmid": "" }, { "name": "regulation of protein catabolic process", "id": "GO:0042176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042176", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38764-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Thr11", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Thr177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Ser178", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Ser182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Thr190", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Ser191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Ser196", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Ser19", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "27821475", "url": "https://glygen.org/publication/PubMed/27821475" }, { "database": "PubMed", "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Thr24", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Ser296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Thr349", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Ser360", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Ser39", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Ser61", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Ser62", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "640", "end_pos": "640", "site_lbl": "Thr640", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "645", "end_pos": "645", "site_lbl": "Thr645", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Ser647", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "649", "end_pos": "649", "site_lbl": "Ser649", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "695", "end_pos": "695", "site_lbl": "Ser695", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38764", "url": "https://www.uniprot.org/uniprotkb/P38764" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "703", "end_pos": "703", "site_lbl": "Ser703", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "952", "end_pos": "952", "site_lbl": "Ser952", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "953", "end_pos": "953", "site_lbl": "Thr953", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38764-1", "start_pos": "989", "end_pos": "989", "site_lbl": "Tyr989", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001069", "url": "https://www.yeastgenome.org/locus/S000001069" }, { "database": "iPTMnet", "id": "P38764", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38764" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ] } ], "record_id": "P38764-1" }, { "uniprot_canonical_ac": "P38782-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 295, "chemical_mass": 32819.0, "gene_names": "MED6;MED6;MTR32", "protein_name": "Mediator of RNA polymerase II transcription subunit 6", "disease": [], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38782-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38782", "url": "https://www.uniprot.org/uniprotkb/P38782" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38782", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38782" }, { "database": "SGD", "id": "S000001100", "url": "https://www.yeastgenome.org/locus/S000001100" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38782-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Thr253", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001100", "url": "https://www.yeastgenome.org/locus/S000001100" }, { "database": "iPTMnet", "id": "P38782", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38782" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38782-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Thr256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38782", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38782" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001100", "url": "https://www.yeastgenome.org/locus/S000001100" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38782-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Thr260", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001100", "url": "https://www.yeastgenome.org/locus/S000001100" }, { "database": "iPTMnet", "id": "P38782", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38782" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P38782-1" }, { "uniprot_canonical_ac": "P38788-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 538, "chemical_mass": 58238.0, "gene_names": "SSZ1;PDR13;SSZ1", "protein_name": "Ribosome-associated complex subunit SSZ1", "disease": [], "biological_process": [ { "name": "'de novo' cotranslational protein folding", "id": "GO:0051083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051083", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "translational frameshifting", "id": "GO:0006452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006452", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38788-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Ser104", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Ser120", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "155", "end_pos": "155", "site_lbl": "Thr155", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Ser204", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Ser377", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Thr405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "429", "end_pos": "429", "site_lbl": "Thr429", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "430", "end_pos": "430", "site_lbl": "Ser430", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Thr438", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Thr461", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Ser477", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "480", "end_pos": "480", "site_lbl": "Ser480", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "493", "end_pos": "493", "site_lbl": "Thr493", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "524", "end_pos": "524", "site_lbl": "Thr524", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001106", "url": "https://www.yeastgenome.org/locus/S000001106" }, { "database": "iPTMnet", "id": "P38788", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38788" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38788-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Ser295", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "F", "comment": "Increases readthrough in translation termination.", "evidence": [ { "database": "UniProtKB", "id": "P38788", "url": "https://www.uniprot.org/uniprotkb/P38788" }, { "database": "PubMed", "id": "15456889", "url": "https://glygen.org/publication/PubMed/15456889" } ] } ] } ], "record_id": "P38788-1" }, { "uniprot_canonical_ac": "P38789-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38789", "url": "https://www.uniprot.org/uniprotkb/P38789" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 453, "chemical_mass": 51764.0, "gene_names": "SSF1;SSF1", "protein_name": "Ribosome biogenesis protein SSF1", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P38789", "url": "https://www.uniprot.org/uniprotkb/P38789" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P38789", "url": "https://www.uniprot.org/uniprotkb/P38789" } ], "pmid": "" } ], "molecular_function": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "P38789", "url": "https://www.uniprot.org/uniprotkb/P38789" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "P38789", "url": "https://www.uniprot.org/uniprotkb/P38789" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "P38789", "url": "https://www.uniprot.org/uniprotkb/P38789" } ], "pmid": "" }, { "name": "regulation of cell size", "id": "GO:0008361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008361", "evidence": [ { "database": "UniProtKB", "id": "P38789", "url": "https://www.uniprot.org/uniprotkb/P38789" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38789-1", "start_pos": "106", "end_pos": "106", "site_lbl": "Thr106", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 106, "start_aa": "Thr", "end_pos": 106, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr106", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P38789-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Thr15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001108", "url": "https://www.yeastgenome.org/locus/S000001108" }, { "database": "iPTMnet", "id": "P38789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38789" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38789-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Tyr254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001108", "url": "https://www.yeastgenome.org/locus/S000001108" }, { "database": "iPTMnet", "id": "P38789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38789" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38789-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Ser256", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001108", "url": "https://www.yeastgenome.org/locus/S000001108" }, { "database": "iPTMnet", "id": "P38789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38789" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38789-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Thr301", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38789", "url": "https://www.uniprot.org/uniprotkb/P38789" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38789", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38789" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001108", "url": "https://www.yeastgenome.org/locus/S000001108" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38789-1" }, { "uniprot_canonical_ac": "P38811-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 3744, "chemical_mass": 433180.0, "gene_names": "TRA1;TRA1", "protein_name": "SAGA complex/NuA4 acetyltransferase complex subunit TRA1", "disease": [ { "disease_id": "DOID:0050564", "name": "autosomal dominant nonsyndromic deafness", "description": "A nonsyndromic deafness characterized by an autosomal dominant inheritance mode.", "url": "https://disease-ontology.org/term/DOID:0050564", "evidence": [ { "id": "0050564", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050564" } ], "weight": 0.0 }, { "disease_id": "DOID:0112166", "name": "autosomal dominant nonsyndromic deafness 75", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in heterozygous mutation in the TRRAP gene on chromosome 7q22.1.", "url": "https://disease-ontology.org/term/DOID:0112166", "evidence": [ { "id": "0112166", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112166" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" }, { "name": "SLIK (SAGA-like) complex", "id": "GO:0046695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046695", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" }, { "name": "TTT Hsp90 cochaperone complex", "id": "GO:0110078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110078", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" }, { "name": "DNA repair-dependent chromatin remodeling", "id": "GO:0140861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140861", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38811-1", "start_pos": "994", "end_pos": "994", "site_lbl": "Thr994", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 994, "start_aa": "Thr", "end_pos": 994, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr994", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "1022", "end_pos": "1022", "site_lbl": "Thr1022", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "1029", "end_pos": "1029", "site_lbl": "Thr1029", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "1225", "end_pos": "1225", "site_lbl": "Ser1225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "1226", "end_pos": "1226", "site_lbl": "Ser1226", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "1227", "end_pos": "1227", "site_lbl": "Ser1227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "1297", "end_pos": "1297", "site_lbl": "Ser1297", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "12", "end_pos": "12", "site_lbl": "Ser12", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "1466", "end_pos": "1466", "site_lbl": "Ser1466", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Ser172", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "2053", "end_pos": "2053", "site_lbl": "Thr2053", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "2055", "end_pos": "2055", "site_lbl": "Ser2055", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "2062", "end_pos": "2062", "site_lbl": "Ser2062", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "2064", "end_pos": "2064", "site_lbl": "Ser2064", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "23", "end_pos": "23", "site_lbl": "Ser23", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "2788", "end_pos": "2788", "site_lbl": "Thr2788", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "3440", "end_pos": "3440", "site_lbl": "Ser3440", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "3452", "end_pos": "3452", "site_lbl": "Ser3452", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Ser542", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P38811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38811" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001141", "url": "https://www.yeastgenome.org/locus/S000001141" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Leu241", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "In TRA1-2; when associated with L-604; R-2733; P-3145; S-3222 and G-3302. Defects in its ability to interact with acidic activators.", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" }, { "database": "PubMed", "id": "11423663", "url": "https://glygen.org/publication/PubMed/11423663" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "2733", "end_pos": "2733", "site_lbl": "Trp2733", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "R", "comment": "In TRA1-2; when associated with S-241; L-604; P-3145; S-3222 and G-3302. Defects in its ability to interact with acidic activators.", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" }, { "database": "PubMed", "id": "11423663", "url": "https://glygen.org/publication/PubMed/11423663" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "3145", "end_pos": "3145", "site_lbl": "Ser3145", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "P", "comment": "In TRA1-2; when associated with S-241; L-604; R-2733; S-3222 and G-3302. Defects in its ability to interact with acidic activators.", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" }, { "database": "PubMed", "id": "11423663", "url": "https://glygen.org/publication/PubMed/11423663" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "3222", "end_pos": "3222", "site_lbl": "Leu3222", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "In TRA1-2; when associated with S-241; L-604; R-2733; P-3145 and G-3302. Defects in its ability to interact with acidic activators.", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" }, { "database": "PubMed", "id": "11423663", "url": "https://glygen.org/publication/PubMed/11423663" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "3302", "end_pos": "3302", "site_lbl": "Asp3302", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "G", "comment": "In TRA1-2; when associated with S-241; L-604; R-2733; P-3145 and S-3222. Defects in its ability to interact with acidic activators.", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" }, { "database": "PubMed", "id": "11423663", "url": "https://glygen.org/publication/PubMed/11423663" } ] } ] }, { "uniprot_canonical_ac": "P38811-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Phe604", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "L", "comment": "In TRA1-2; when associated with S-241; R-2733; P-3145; S-3222 and G-3302. Defects in its ability to interact with acidic activators.", "evidence": [ { "database": "UniProtKB", "id": "P38811", "url": "https://www.uniprot.org/uniprotkb/P38811" }, { "database": "PubMed", "id": "11423663", "url": "https://glygen.org/publication/PubMed/11423663" } ] } ] } ], "record_id": "P38811-1" }, { "uniprot_canonical_ac": "P38873-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1557, "chemical_mass": 177609.0, "gene_names": "KOG1;H9998.14;KOG1;LAS24", "protein_name": "Target of rapamycin complex 1 subunit KOG1", "disease": [ { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "TORC1 complex", "id": "GO:0031931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031931", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" } ], "biological_process": [ { "name": "response to nutrient", "id": "GO:0007584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007584", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "TOR signaling", "id": "GO:0031929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031929", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "P38873", "url": "https://www.uniprot.org/uniprotkb/P38873" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38873-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Thr256", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 256, "start_aa": "Thr", "end_pos": 256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr256", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ] }, { "uniprot_canonical_ac": "P38873-1", "start_pos": "1031", "end_pos": "1031", "site_lbl": "Ser1031", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38873" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ] }, { "uniprot_canonical_ac": "P38873-1", "start_pos": "1032", "end_pos": "1032", "site_lbl": "Ser1032", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001229", "url": "https://www.yeastgenome.org/locus/S000001229" }, { "database": "iPTMnet", "id": "P38873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38873-1", "start_pos": "1045", "end_pos": "1045", "site_lbl": "Ser1045", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001229", "url": "https://www.yeastgenome.org/locus/S000001229" }, { "database": "iPTMnet", "id": "P38873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38873-1", "start_pos": "478", "end_pos": "478", "site_lbl": "Ser478", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38873" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000001229", "url": "https://www.yeastgenome.org/locus/S000001229" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38873-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Thr481", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38873" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000001229", "url": "https://www.yeastgenome.org/locus/S000001229" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38873-1", "start_pos": "491", "end_pos": "491", "site_lbl": "Ser491", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38873" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "26439012", "url": "https://glygen.org/publication/PubMed/26439012" }, { "database": "PubMed", "id": "33853774", "url": "https://glygen.org/publication/PubMed/33853774" }, { "database": "SGD", "id": "S000001229", "url": "https://www.yeastgenome.org/locus/S000001229" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38873-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Thr492", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38873" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001229", "url": "https://www.yeastgenome.org/locus/S000001229" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P38873-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Ser494", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38873" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "26439012", "url": "https://glygen.org/publication/PubMed/26439012" }, { "database": "PubMed", "id": "33853774", "url": "https://glygen.org/publication/PubMed/33853774" }, { "database": "SGD", "id": "S000001229", "url": "https://www.yeastgenome.org/locus/S000001229" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38873-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Ser503", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001229", "url": "https://www.yeastgenome.org/locus/S000001229" }, { "database": "iPTMnet", "id": "P38873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38873" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] } ], "record_id": "P38873-1" }, { "uniprot_canonical_ac": "P38886-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38886", "url": "https://www.uniprot.org/uniprotkb/P38886" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 268, "chemical_mass": 29747.0, "gene_names": "RPN10;MCB1;RPN10;SUN1", "protein_name": "26S proteasome regulatory subunit RPN10", "disease": [], "molecular_function": [ { "name": "K48-linked polyubiquitin modification-dependent protein binding", "id": "GO:0036435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036435", "evidence": [ { "database": "UniProtKB", "id": "P38886", "url": "https://www.uniprot.org/uniprotkb/P38886" } ], "pmid": "" }, { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "P38886", "url": "https://www.uniprot.org/uniprotkb/P38886" } ], "pmid": "" } ], "cellular_component": [ { "name": "proteasome regulatory particle, base subcomplex", "id": "GO:0008540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008540", "evidence": [ { "database": "UniProtKB", "id": "P38886", "url": "https://www.uniprot.org/uniprotkb/P38886" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38886", "url": "https://www.uniprot.org/uniprotkb/P38886" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38886", "url": "https://www.uniprot.org/uniprotkb/P38886" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "P38886", "url": "https://www.uniprot.org/uniprotkb/P38886" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "P38886", "url": "https://www.uniprot.org/uniprotkb/P38886" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "P38886", "url": "https://www.uniprot.org/uniprotkb/P38886" } ], "pmid": "" }, { "name": "proteasome assembly", "id": "GO:0043248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043248", "evidence": [ { "database": "UniProtKB", "id": "P38886", "url": "https://www.uniprot.org/uniprotkb/P38886" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38886-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Ser116", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001243", "url": "https://www.yeastgenome.org/locus/S000001243" }, { "database": "iPTMnet", "id": "P38886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38886" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ] }, { "uniprot_canonical_ac": "P38886-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001243", "url": "https://www.yeastgenome.org/locus/S000001243" }, { "database": "iPTMnet", "id": "P38886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38886-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Ser209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001243", "url": "https://www.yeastgenome.org/locus/S000001243" }, { "database": "iPTMnet", "id": "P38886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38886" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38886-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001243", "url": "https://www.yeastgenome.org/locus/S000001243" }, { "database": "iPTMnet", "id": "P38886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38886" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38886-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Ser259", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38886" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000001243", "url": "https://www.yeastgenome.org/locus/S000001243" }, { "database": "PubMed", "id": "20486117", "url": "https://glygen.org/publication/PubMed/20486117" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38886-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001243", "url": "https://www.yeastgenome.org/locus/S000001243" }, { "database": "iPTMnet", "id": "P38886", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38886" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38886-1" }, { "uniprot_canonical_ac": "P38932-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 577, "chemical_mass": 67017.0, "gene_names": "VPS45;STT10;VPL28;VPS45", "protein_name": "Vacuolar protein sorting-associated protein 45", "disease": [ { "disease_id": "DOID:0112132", "name": "severe congenital neutropenia 5", "description": "A severe congenital neutropenia characterized by neutropenia and neutrophil dysfunction, a lack of response to G-CSF, life-threatening infections, bone marrow fibrosis, and renal extramedullary hematopoiesis that has_material_basis_in homozygous or compound heterozygous mutation in the VPS45 gene on chromosome 1q21.2.", "url": "https://disease-ontology.org/term/DOID:0112132", "evidence": [ { "id": "0112132", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112132" } ], "weight": 0.0 } ], "biological_process": [ { "name": "Golgi vesicle fusion to target membrane", "id": "GO:0048210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048210", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "vacuole organization", "id": "GO:0007033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007033", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "vacuole inheritance", "id": "GO:0000011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000011", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "cytoplasm to vacuole targeting by the Cvt pathway", "id": "GO:0032258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032258", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "positive regulation of SNARE complex assembly", "id": "GO:0035543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035543", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "P38932", "url": "https://www.uniprot.org/uniprotkb/P38932" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38932-1", "start_pos": "572", "end_pos": "572", "site_lbl": "Ser572", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38932", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38932" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ] } ], "record_id": "P38932-1" }, { "uniprot_canonical_ac": "P38960-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 494, "chemical_mass": 57511.0, "gene_names": "STN1;D4456;STN1;YD8554.15", "protein_name": "Protein STN1", "disease": [], "biological_process": [ { "name": "telomere capping", "id": "GO:0016233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016233", "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" } ], "pmid": "" }, { "name": "negative regulation of telomere maintenance via telomerase", "id": "GO:0032211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032211", "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" } ], "pmid": "" }, { "name": "regulation of telomere maintenance via telomerase", "id": "GO:0032210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032210", "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" } ], "pmid": "" } ], "molecular_function": [ { "name": "single-stranded telomeric DNA binding", "id": "GO:0043047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043047", "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" } ], "pmid": "" }, { "name": "translation elongation factor binding", "id": "GO:0061770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061770", "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" } ], "pmid": "" } ], "cellular_component": [ { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" } ], "pmid": "" }, { "name": "CST complex", "id": "GO:1990879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990879", "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38960-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Thr223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P38960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38960" }, { "database": "PubMed", "id": "24164896", "url": "https://glygen.org/publication/PubMed/24164896" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002489", "url": "https://www.yeastgenome.org/locus/S000002489" }, { "database": "iPTMnet", "id": "P38960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38960" }, { "database": "PubMed", "id": "24164896", "url": "https://glygen.org/publication/PubMed/24164896" } ] } ] }, { "uniprot_canonical_ac": "P38960-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Ser250", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "evidence": [ { "database": "iPTMnet", "id": "P38960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38960" }, { "database": "PubMed", "id": "24164896", "url": "https://glygen.org/publication/PubMed/24164896" } ] }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000002489", "url": "https://www.yeastgenome.org/locus/S000002489" }, { "database": "iPTMnet", "id": "P38960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38960" }, { "database": "PubMed", "id": "24164896", "url": "https://glygen.org/publication/PubMed/24164896" } ] } ] }, { "uniprot_canonical_ac": "P38960-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Ser283", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38960", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38960" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002489", "url": "https://www.yeastgenome.org/locus/S000002489" } ] } ] }, { "uniprot_canonical_ac": "P38960-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Asp397", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Modest telomere elongation phenotype.", "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" }, { "database": "PubMed", "id": "20008938", "url": "https://glygen.org/publication/PubMed/20008938" } ] } ] }, { "uniprot_canonical_ac": "P38960-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Trp466", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "E", "comment": "Elongated telomeres.", "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" }, { "database": "PubMed", "id": "20008938", "url": "https://glygen.org/publication/PubMed/20008938" } ] }, { "sequence_org": "W", "sequence_mut": "R", "comment": "Elongated telomeres and severe growth defects.", "evidence": [ { "database": "UniProtKB", "id": "P38960", "url": "https://www.uniprot.org/uniprotkb/P38960" }, { "database": "PubMed", "id": "20008938", "url": "https://glygen.org/publication/PubMed/20008938" } ] } ] } ], "record_id": "P38960-1" }, { "uniprot_canonical_ac": "P38989-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 1170, "chemical_mass": 133928.0, "gene_names": "SMC2;SMC2", "protein_name": "Structural maintenance of chromosomes protein 2", "disease": [ { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "minor groove of adenine-thymine-rich DNA binding", "id": "GO:0003680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003680", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "DNA secondary structure binding", "id": "GO:0000217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000217", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "condensed chromosome", "id": "GO:0000793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000793", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "condensin complex", "id": "GO:0000796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000796", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "mitotic chromosome condensation", "id": "GO:0007076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007076", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "chromosome condensation", "id": "GO:0030261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030261", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "rDNA chromatin condensation", "id": "GO:0070550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070550", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "tRNA gene clustering", "id": "GO:0070058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070058", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" }, { "name": "negative regulation of meiotic DNA double-strand break formation", "id": "GO:1903342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903342", "evidence": [ { "database": "UniProtKB", "id": "P38989", "url": "https://www.uniprot.org/uniprotkb/P38989" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P38989-1", "start_pos": "1085", "end_pos": "1085", "site_lbl": "Ser1085", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P38989", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38989" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001927", "url": "https://www.yeastgenome.org/locus/S000001927" } ] } ] }, { "uniprot_canonical_ac": "P38989-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Ser313", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001927", "url": "https://www.yeastgenome.org/locus/S000001927" }, { "database": "iPTMnet", "id": "P38989", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38989" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38989-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Thr317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001927", "url": "https://www.yeastgenome.org/locus/S000001927" }, { "database": "iPTMnet", "id": "P38989", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38989" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38989-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Ser318", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001927", "url": "https://www.yeastgenome.org/locus/S000001927" }, { "database": "iPTMnet", "id": "P38989", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38989" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38989-1", "start_pos": "719", "end_pos": "719", "site_lbl": "Ser719", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001927", "url": "https://www.yeastgenome.org/locus/S000001927" }, { "database": "iPTMnet", "id": "P38989", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38989" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38989-1", "start_pos": "724", "end_pos": "724", "site_lbl": "Ser724", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001927", "url": "https://www.yeastgenome.org/locus/S000001927" }, { "database": "iPTMnet", "id": "P38989", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38989" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P38989-1", "start_pos": "812", "end_pos": "812", "site_lbl": "Ser812", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001927", "url": "https://www.yeastgenome.org/locus/S000001927" }, { "database": "iPTMnet", "id": "P38989", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P38989" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P38989-1" }, { "uniprot_canonical_ac": "P39013-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 349, "chemical_mass": 40297.0, "gene_names": "END3;END3;N2307", "protein_name": "Actin cytoskeleton-regulatory complex protein END3", "disease": [ { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "actin cortical patch", "id": "GO:0030479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030479", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "mating projection tip", "id": "GO:0043332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043332", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "actin cytoskeleton-regulatory complex", "id": "GO:1990964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990964", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "ascospore wall assembly", "id": "GO:0030476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030476", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P39013-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005028", "url": "https://www.yeastgenome.org/locus/S000005028" }, { "database": "iPTMnet", "id": "P39013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39013" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39013-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Ser269", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005028", "url": "https://www.yeastgenome.org/locus/S000005028" }, { "database": "iPTMnet", "id": "P39013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39013" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39013-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Tyr274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39013" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005028", "url": "https://www.yeastgenome.org/locus/S000005028" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39013-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Ser276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39013", "url": "https://www.uniprot.org/uniprotkb/P39013" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P39013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39013" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005028", "url": "https://www.yeastgenome.org/locus/S000005028" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39013-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Thr278", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005028", "url": "https://www.yeastgenome.org/locus/S000005028" }, { "database": "iPTMnet", "id": "P39013", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39013" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] } ], "record_id": "P39013-1" }, { "uniprot_canonical_ac": "P39014-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 640, "chemical_mass": 72835.0, "gene_names": "MET30;MET30;ZRG11", "protein_name": "F-box protein MET30", "disease": [], "biological_process": [ { "name": "response to arsenic-containing substance", "id": "GO:0046685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046685", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "response to cadmium ion", "id": "GO:0046686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046686", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "methionine biosynthetic process", "id": "GO:0009086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009086", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "cysteine biosynthetic process", "id": "GO:0019344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019344", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "nuclear SCF ubiquitin ligase complex", "id": "GO:0043224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043224", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" }, { "name": "molecular sensor activity", "id": "GO:0140299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140299", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P39014-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39014", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39014" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "24648496", "url": "https://glygen.org/publication/PubMed/24648496" }, { "database": "SGD", "id": "S000001308", "url": "https://www.yeastgenome.org/locus/S000001308" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Thr107", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001308", "url": "https://www.yeastgenome.org/locus/S000001308" }, { "database": "iPTMnet", "id": "P39014", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39014" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Thr307", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001308", "url": "https://www.yeastgenome.org/locus/S000001308" }, { "database": "iPTMnet", "id": "P39014", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39014" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Thr45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39014", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39014" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001308", "url": "https://www.yeastgenome.org/locus/S000001308" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Ser47", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39014", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39014" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "24648496", "url": "https://glygen.org/publication/PubMed/24648496" }, { "database": "SGD", "id": "S000001308", "url": "https://www.yeastgenome.org/locus/S000001308" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Ser48", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39014", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39014" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001308", "url": "https://www.yeastgenome.org/locus/S000001308" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Ser67", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P39014", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39014" }, { "database": "SGD", "id": "S000001308", "url": "https://www.yeastgenome.org/locus/S000001308" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Ser69", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39014", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39014" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001308", "url": "https://www.yeastgenome.org/locus/S000001308" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Ser70", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39014", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39014" }, { "database": "PubMed", "id": "24648496", "url": "https://glygen.org/publication/PubMed/24648496" }, { "database": "SGD", "id": "S000001308", "url": "https://www.yeastgenome.org/locus/S000001308" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000001308", "url": "https://www.yeastgenome.org/locus/S000001308" }, { "database": "iPTMnet", "id": "P39014", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39014" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Leu187", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Strongly reduces nuclear localization; inhibits interaction with SKP1/CBF3D.", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" }, { "database": "PubMed", "id": "14660673", "url": "https://glygen.org/publication/PubMed/14660673" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Glu190", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Strongly reduces nuclear localization; inhibits interaction with SKP1/CBF3D.", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" }, { "database": "PubMed", "id": "14660673", "url": "https://glygen.org/publication/PubMed/14660673" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "386", "end_pos": "386", "site_lbl": "Leu386", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Inactivates MET30 and prevents MET4 interaction; when associated with A-425 and A-467.", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" }, { "database": "PubMed", "id": "15883825", "url": "https://glygen.org/publication/PubMed/15883825" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "425", "end_pos": "425", "site_lbl": "Asn425", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Inactivates MET30 and prevents MET4 interaction; when associated with D-530 or D-386 and A-467.", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" }, { "database": "PubMed", "id": "15883825", "url": "https://glygen.org/publication/PubMed/15883825" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "467", "end_pos": "467", "site_lbl": "Gln467", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Inactivates MET30 and prevents MET4 interaction; when associated with D-386 and A-425.", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" }, { "database": "PubMed", "id": "15883825", "url": "https://glygen.org/publication/PubMed/15883825" } ] } ] }, { "uniprot_canonical_ac": "P39014-1", "start_pos": "530", "end_pos": "530", "site_lbl": "Leu530", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Inactivates MET30 and prevents MET4 interaction; when associated with A-425.", "evidence": [ { "database": "UniProtKB", "id": "P39014", "url": "https://www.uniprot.org/uniprotkb/P39014" }, { "database": "PubMed", "id": "15883825", "url": "https://glygen.org/publication/PubMed/15883825" } ] } ] } ], "record_id": "P39014-1" }, { "uniprot_canonical_ac": "P39015-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 273, "chemical_mass": 29995.0, "gene_names": "STM1;L9634.1;MPT4;STM1;STO1", "protein_name": "Suppressor protein STM1", "disease": [], "molecular_function": [ { "name": "triplex DNA binding", "id": "GO:0045142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045142", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "translation repressor activity", "id": "GO:0030371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030371", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "translation elongation factor binding", "id": "GO:0061770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061770", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "TOR signaling", "id": "GO:0031929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031929", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "translational elongation", "id": "GO:0006414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006414", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "regulation of translational initiation in response to stress", "id": "GO:0043558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043558", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" }, { "name": "ribosome hibernation", "id": "GO:0141014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141014", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P39015-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Thr146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Ser150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Thr181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "36691768", "url": "https://glygen.org/publication/PubMed/36691768" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Tyr187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Thr191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Thr218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "36691768", "url": "https://glygen.org/publication/PubMed/36691768" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Ser229", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Thr248", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Thr252", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Ser254", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Thr257", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Ser267", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Ser271", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Thr30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "36691768", "url": "https://glygen.org/publication/PubMed/36691768" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" }, { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "36691768", "url": "https://glygen.org/publication/PubMed/36691768" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Ser45", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" }, { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "36691768", "url": "https://glygen.org/publication/PubMed/36691768" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "36691768", "url": "https://glygen.org/publication/PubMed/36691768" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39015", "url": "https://www.uniprot.org/uniprotkb/P39015" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "36691768", "url": "https://glygen.org/publication/PubMed/36691768" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Ser79", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Thr81", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Thr82", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] }, { "uniprot_canonical_ac": "P39015-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Ser95", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000004140", "url": "https://www.yeastgenome.org/locus/S000004140" }, { "database": "iPTMnet", "id": "P39015", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39015" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ] } ], "record_id": "P39015-1" }, { "uniprot_canonical_ac": "P39016-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 859, "chemical_mass": 95422.0, "gene_names": "MPT5;BIC834;HTR1;MPT5;PUF5;UTH4", "protein_name": "Suppressor protein MPT5", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" } ], "pmid": "" } ], "biological_process": [ { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" } ], "pmid": "" }, { "name": "negative regulation of translational initiation", "id": "GO:0045947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045947", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900153", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" } ], "pmid": "" }, { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" } ], "pmid": "" }, { "name": "regulation of G1 to G0 transition", "id": "GO:1903450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903450", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P39016-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Thr167", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 167, "start_aa": "Thr", "end_pos": 167, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr167", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 176, "start_aa": "Ser", "end_pos": 176, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser176", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P39016", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P39016" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Ser178", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 178, "start_aa": "Ser", "end_pos": 178, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser178", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P39016", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P39016" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 183, "start_aa": "Ser", "end_pos": 183, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser183", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P39016", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P39016" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "47", "end_pos": "47", "site_lbl": "Thr47", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 47, "start_aa": "Thr", "end_pos": 47, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr47", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "834", "end_pos": "834", "site_lbl": "Ser834", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 834, "start_aa": "Ser", "end_pos": 834, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser834", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P39016", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P39016" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Thr143", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "148", "end_pos": "148", "site_lbl": "Ser148", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Ser150", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ser156", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Ser163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "607", "end_pos": "607", "site_lbl": "Ser607", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "614", "end_pos": "614", "site_lbl": "Ser614", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "662", "end_pos": "662", "site_lbl": "Ser662", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "672", "end_pos": "672", "site_lbl": "Ser672", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "674", "end_pos": "674", "site_lbl": "Ser674", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "675", "end_pos": "675", "site_lbl": "Ser675", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "677", "end_pos": "677", "site_lbl": "Thr677", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "684", "end_pos": "684", "site_lbl": "Tyr684", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "692", "end_pos": "692", "site_lbl": "Ser692", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "725", "end_pos": "725", "site_lbl": "Ser725", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "743", "end_pos": "743", "site_lbl": "Ser743", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "749", "end_pos": "749", "site_lbl": "Ser749", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "751", "end_pos": "751", "site_lbl": "Ser751", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Ser752", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "753", "end_pos": "753", "site_lbl": "Ser753", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "756", "end_pos": "756", "site_lbl": "Thr756", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "820", "end_pos": "820", "site_lbl": "Ser820", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" } ] } ] }, { "uniprot_canonical_ac": "P39016-1", "start_pos": "838", "end_pos": "838", "site_lbl": "Ser838", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39016", "url": "https://www.uniprot.org/uniprotkb/P39016" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P39016", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39016" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003146", "url": "https://www.yeastgenome.org/locus/S000003146" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P39016-1" }, { "uniprot_canonical_ac": "P39103-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P39103", "url": "https://www.uniprot.org/uniprotkb/P39103" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 70, "chemical_mass": 7959.0, "gene_names": "COX14;COX14;YM4987.06C", "protein_name": "Cytochrome c oxidase assembly protein COX14", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P39103", "url": "https://www.uniprot.org/uniprotkb/P39103" } ], "pmid": "" }, { "name": "mitochondrial envelope", "id": "GO:0005740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005740", "evidence": [ { "database": "UniProtKB", "id": "P39103", "url": "https://www.uniprot.org/uniprotkb/P39103" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P39103", "url": "https://www.uniprot.org/uniprotkb/P39103" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "P39103", "url": "https://www.uniprot.org/uniprotkb/P39103" } ], "pmid": "" } ], "biological_process": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "P39103", "url": "https://www.uniprot.org/uniprotkb/P39103" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "P39103", "url": "https://www.uniprot.org/uniprotkb/P39103" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial translation", "id": "GO:0070130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070130", "evidence": [ { "database": "UniProtKB", "id": "P39103", "url": "https://www.uniprot.org/uniprotkb/P39103" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P39103-1" }, { "uniprot_canonical_ac": "P39111-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P39111", "url": "https://www.uniprot.org/uniprotkb/P39111" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 118, "chemical_mass": 13461.0, "gene_names": "VMA7;VMA7", "protein_name": "V-type proton ATPase subunit F", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P39111", "url": "https://www.uniprot.org/uniprotkb/P39111" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P39111", "url": "https://www.uniprot.org/uniprotkb/P39111" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V1 domain", "id": "GO:0000221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000221", "evidence": [ { "database": "UniProtKB", "id": "P39111", "url": "https://www.uniprot.org/uniprotkb/P39111" } ], "pmid": "" }, { "name": "fungal-type vacuole membrane", "id": "GO:0000329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000329", "evidence": [ { "database": "UniProtKB", "id": "P39111", "url": "https://www.uniprot.org/uniprotkb/P39111" } ], "pmid": "" } ], "biological_process": [ { "name": "endosomal lumen acidification", "id": "GO:0048388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048388", "evidence": [ { "database": "UniProtKB", "id": "P39111", "url": "https://www.uniprot.org/uniprotkb/P39111" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "P39111", "url": "https://www.uniprot.org/uniprotkb/P39111" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "P39111", "url": "https://www.uniprot.org/uniprotkb/P39111" } ], "pmid": "" }, { "name": "Golgi lumen acidification", "id": "GO:0061795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061795", "evidence": [ { "database": "UniProtKB", "id": "P39111", "url": "https://www.uniprot.org/uniprotkb/P39111" } ], "pmid": "" } ], "molecular_function": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "P39111", "url": "https://www.uniprot.org/uniprotkb/P39111" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P39111-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Thr29", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003252", "url": "https://www.yeastgenome.org/locus/S000003252" }, { "database": "iPTMnet", "id": "P39111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39111" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39111-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Ser83", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000003252", "url": "https://www.yeastgenome.org/locus/S000003252" }, { "database": "iPTMnet", "id": "P39111", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39111" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P39111-1" }, { "uniprot_canonical_ac": "P39683-1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "length": 429, "chemical_mass": 49019.0, "gene_names": "NPT1;NPT1", "protein_name": "Nicotinate phosphoribosyltransferase", "disease": [], "biological_process": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ], "pmid": "" }, { "name": "rDNA heterochromatin formation", "id": "GO:0000183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000183", "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ], "pmid": "" }, { "name": "nicotinate nucleotide salvage", "id": "GO:0019358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019358", "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ], "pmid": "" }, { "name": "NAD+ biosynthetic process via the salvage pathway", "id": "GO:0034355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034355", "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ], "pmid": "" } ], "molecular_function": [ { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ], "pmid": "" }, { "name": "nicotinate phosphoribosyltransferase activity", "id": "GO:0004516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004516", "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P39683-1", "start_pos": "232", "end_pos": "232", "site_lbl": "His232", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P39683", "url": "https://www.uniprot.org/uniprotkb/P39683" } ] } ] }, { "uniprot_canonical_ac": "P39683-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Ser297", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005735", "url": "https://www.yeastgenome.org/locus/S000005735" }, { "database": "iPTMnet", "id": "P39683", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39683" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39683-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Ser329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005735", "url": "https://www.yeastgenome.org/locus/S000005735" }, { "database": "iPTMnet", "id": "P39683", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39683" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39683-1", "start_pos": "365", "end_pos": "365", "site_lbl": "Ser365", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005735", "url": "https://www.yeastgenome.org/locus/S000005735" }, { "database": "iPTMnet", "id": "P39683", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39683" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39683-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Ser371", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005735", "url": "https://www.yeastgenome.org/locus/S000005735" }, { "database": "iPTMnet", "id": "P39683", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39683" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39683-1", "start_pos": "418", "end_pos": "418", "site_lbl": "Ser418", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005735", "url": "https://www.yeastgenome.org/locus/S000005735" }, { "database": "iPTMnet", "id": "P39683", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39683" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39683-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "iPTMnet", "id": "P39683", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39683" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005735", "url": "https://www.yeastgenome.org/locus/S000005735" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] }, { "uniprot_canonical_ac": "P39683-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005735", "url": "https://www.yeastgenome.org/locus/S000005735" }, { "database": "iPTMnet", "id": "P39683", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39683" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ] }, { "uniprot_canonical_ac": "P39683-1", "start_pos": "91", "end_pos": "91", "site_lbl": "Ser91", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "SGD", "id": "S000005735", "url": "https://www.yeastgenome.org/locus/S000005735" }, { "database": "iPTMnet", "id": "P39683", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P39683" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ] } ], "record_id": "P39683-1" } ]